DE69721006D1 - Verwendung des modifizierten eigenen blutes zur behandlung von autoimmunerkrankungen - Google Patents
Verwendung des modifizierten eigenen blutes zur behandlung von autoimmunerkrankungenInfo
- Publication number
- DE69721006D1 DE69721006D1 DE69721006T DE69721006T DE69721006D1 DE 69721006 D1 DE69721006 D1 DE 69721006D1 DE 69721006 T DE69721006 T DE 69721006T DE 69721006 T DE69721006 T DE 69721006T DE 69721006 D1 DE69721006 D1 DE 69721006D1
- Authority
- DE
- Germany
- Prior art keywords
- blood
- autoimmune diseases
- modified
- treatment
- aliquot
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 210000004369 blood Anatomy 0.000 title abstract 3
- 239000008280 blood Substances 0.000 title abstract 3
- 208000023275 Autoimmune disease Diseases 0.000 title abstract 2
- 229960005486 vaccine Drugs 0.000 abstract 2
- 102000002812 Heat-Shock Proteins Human genes 0.000 abstract 1
- 108010004889 Heat-Shock Proteins Proteins 0.000 abstract 1
- 230000001363 autoimmune Effects 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 230000003247 decreasing effect Effects 0.000 abstract 1
- 210000000265 leukocyte Anatomy 0.000 abstract 1
- 210000004698 lymphocyte Anatomy 0.000 abstract 1
- 239000007800 oxidant agent Substances 0.000 abstract 1
- 230000005855 radiation Effects 0.000 abstract 1
- 206010039073 rheumatoid arthritis Diseases 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3681—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/40—Peroxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/10—Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person
- A61K41/17—Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person by ultraviolet [UV] or infrared [IR] light, X-rays or gamma rays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3681—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
- A61M1/3683—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation using photoactive agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/32—Oxygenators without membranes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/02—Gases
- A61M2202/0216—Ozone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/02—Gases
- A61M2202/0266—Nitrogen (N)
- A61M2202/0275—Nitric oxide [NO]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/05—General characteristics of the apparatus combined with other kinds of therapy
- A61M2205/051—General characteristics of the apparatus combined with other kinds of therapy with radiation therapy
- A61M2205/053—General characteristics of the apparatus combined with other kinds of therapy with radiation therapy ultraviolet
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/81—Drug, bio-affecting and body treating compositions involving autoimmunity, allergy, immediate hypersensitivity, delayed hypersensitivity, immunosuppression, immunotolerance, or anergy
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9617611 | 1996-08-22 | ||
GBGB9617611.0A GB9617611D0 (en) | 1996-08-22 | 1996-08-22 | Treatment of autoimmune disease |
US754348 | 1996-11-22 | ||
US08/754,348 US5980954A (en) | 1992-02-07 | 1996-11-22 | Treatment of autoimmune diseases |
PCT/CA1997/000564 WO1998007436A1 (en) | 1996-08-22 | 1997-08-11 | Treatment of autoimmune diseases |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69721006D1 true DE69721006D1 (de) | 2003-05-22 |
DE69721006T2 DE69721006T2 (de) | 2004-01-22 |
Family
ID=26309905
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69721006T Expired - Fee Related DE69721006T2 (de) | 1996-08-22 | 1997-08-11 | Verwendung des modifizierten eigenen blutes zur behandlung von autoimmunerkrankungen |
Country Status (12)
Country | Link |
---|---|
US (2) | US5980954A (de) |
EP (1) | EP0920322B9 (de) |
JP (1) | JP3883013B2 (de) |
AT (1) | ATE237339T1 (de) |
AU (1) | AU724265B2 (de) |
CA (1) | CA2263911C (de) |
DE (1) | DE69721006T2 (de) |
DK (1) | DK0920322T3 (de) |
ES (1) | ES2199367T3 (de) |
NZ (1) | NZ334635A (de) |
PT (1) | PT920322E (de) |
WO (1) | WO1998007436A1 (de) |
Families Citing this family (57)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9617611D0 (en) * | 1996-08-22 | 1996-10-02 | Vasogen Inc | Treatment of autoimmune disease |
US6669965B2 (en) * | 1992-02-07 | 2003-12-30 | Vasogen Ireland Limited | Method of treating atherosclerosis |
US5980954A (en) | 1992-02-07 | 1999-11-09 | Vasogen Ireland Limited | Treatment of autoimmune diseases |
US6066489A (en) | 1996-08-30 | 2000-05-23 | Arrow International, Inc. | Method for treating blood borne viral pathogens such as immunodeficiency virus |
CA2206180A1 (en) * | 1997-05-27 | 1998-11-27 | Vasogen Inc. | Treatment of chronic post-traumatic pain syndromes |
AU741181B2 (en) * | 1997-09-12 | 2001-11-22 | Centre De Recherche Du Centre Hospitalier De L'universite De Montreal | Treatment of stress and preconditioning against stress |
CA2244554A1 (en) * | 1998-07-30 | 2000-01-30 | Vasogen Inc. | Inhibition of graft versus host disease |
WO2000029003A2 (en) * | 1998-11-13 | 2000-05-25 | Vasogen Ireland Limited | Method for preventing and reversing atherosclerosis in mammals |
US6264646B1 (en) | 1998-11-13 | 2001-07-24 | Vasogen Ireland Limited | Method for preventing and reversing atherosclerosis in mammals |
WO2000041705A1 (en) * | 1999-01-12 | 2000-07-20 | Vasogen Ireland Limited | Pre-conditioning against cell death |
CA2269364A1 (en) * | 1999-04-19 | 2000-10-19 | Vasogen Ireland Limited | Treatment of inflammatory and allergic disorders |
CA2271190A1 (en) * | 1999-05-06 | 2000-11-06 | Vasogen Ireland Limited | Improved method for treating mammals with modified mammalian blood |
CA2381730A1 (en) * | 1999-09-16 | 2001-03-22 | Vasogen Ireland Limited | Apparatus and process for conditioning mammalian blood |
JP2003510284A (ja) * | 1999-09-24 | 2003-03-18 | バソジェン アイルランド リミテッド | アテローム性動脈硬化症の処置のための併用療法 |
CA2296997A1 (en) * | 2000-01-18 | 2001-07-18 | Vasogen Ireland Limited | Treatment of congestive heart failure |
CA2297448A1 (en) * | 2000-01-28 | 2001-07-28 | Vasogen Inc. | Improved inhibition of graft versus host disease |
US6800300B1 (en) | 2000-03-31 | 2004-10-05 | Vasogen Ireland Limited | Method for treating autoimmune and alloimmune diseases |
WO2001079555A2 (en) * | 2000-04-14 | 2001-10-25 | Millennium Pharmaceuticals, Inc. | Roles of jak/stat family members in tolerance induction |
US6970740B2 (en) * | 2000-04-19 | 2005-11-29 | Clemson University | UVC rediation therapy for leukemia |
US6585676B1 (en) * | 2000-04-19 | 2003-07-01 | Clemson University | UVC radiation therapy for chronic lymphocytic leukemia |
CA2308105A1 (en) * | 2000-05-11 | 2001-11-11 | Vasogen Ireland Limited | Treatment of il-10 deficiencies |
CA2309417A1 (en) * | 2000-05-25 | 2001-11-25 | Anthony E. Bolton | Apoptotic entities for use in treatment of endothelium dysfunction disorders |
CA2309518A1 (en) * | 2000-05-25 | 2001-11-25 | Vasogen Ireland Limited | Apoptotic entities for use in treatment of t-cell-mediated and inflammatory disorders |
CA2309424A1 (en) * | 2000-05-25 | 2001-11-25 | Vasogen Ireland Limited | Apoptotic entities for use in treatment of neurodegenerative and other neurological disorders |
CA2324199A1 (en) * | 2000-10-25 | 2002-04-25 | Vasogen Ireland Limited | Chronic lymphocytic leukemia treatment |
US20020090360A1 (en) * | 2000-12-05 | 2002-07-11 | Bolton Anthony E. | Inflammatory cytokine secretion inhibition |
CA2327631A1 (en) * | 2000-12-05 | 2002-06-05 | Vasogen Ireland Limited | Inflammatory cytokine secretion inhibition |
CA2327630A1 (en) * | 2000-12-05 | 2002-06-05 | Vasogen Ireland Limited | Transforming growth factor regulation |
CA2333494A1 (en) * | 2001-02-01 | 2002-08-01 | Vasogen Ireland Limited | Blood brain barrier modulation |
US7122208B2 (en) * | 2001-04-06 | 2006-10-17 | Vasogen Ireland Limited | Compositions containing apoptotic entities |
EP1990055A3 (de) * | 2001-11-29 | 2011-11-16 | Therakos, Inc. | Verfahren zur Vorbehandlung einer Person durch extrakorporale Photopherese und/oder apoptotische Zellen |
US20050244298A1 (en) * | 2002-04-10 | 2005-11-03 | Smith Eldon R | Electrocardiographic aspects of chf treatment |
JP3927922B2 (ja) * | 2003-05-21 | 2007-06-13 | Ykk株式会社 | スライドファスナー用スプリング体及び同スプリング体が装着されたスライダー |
US7368542B2 (en) | 2003-06-09 | 2008-05-06 | Redox-Reactive Reagents Llc | Method of altering the binding specificity of plasma proteins by oxidation-reduction reactions |
US7892751B2 (en) * | 2003-06-09 | 2011-02-22 | Redox-Reactive Reagents Llc | Method of detecting or diagnosing of a neurodegenerative disease or condition |
US9557325B2 (en) * | 2003-06-09 | 2017-01-31 | Redox-Reactive Reagents Llc | Method of altering the binding specificity of proteins by oxidation-reduction reactions |
US20050189302A1 (en) * | 2003-07-31 | 2005-09-01 | Latino Joseph S. | Viral inactivation using ozone |
US20100316727A1 (en) * | 2003-07-31 | 2010-12-16 | Latino Joseph S | Treatment of inflammatory disorders with ozone |
US7736494B2 (en) * | 2003-07-31 | 2010-06-15 | Acquisci, Inc. | Ozone delivery system including a variable pitch gas-fluid contact device |
US20100316730A1 (en) * | 2003-07-31 | 2010-12-16 | Latino Joseph S | Treatment of cardiovascular diseases with ozone |
US20100318014A1 (en) * | 2003-07-31 | 2010-12-16 | Latino Joseph S | Treatment of acute ischemic brain stroke with ozone |
WO2005025712A2 (en) * | 2003-07-31 | 2005-03-24 | Lipidviro Tech | Viral inactivation using ozone |
TR201816556T4 (tr) * | 2004-04-02 | 2018-11-21 | Swedish Orphan Biovitrum Ab Publ | Il-1ra agregasyonunun azaltilmasina yöneli̇k yöntemler |
WO2006115509A2 (en) * | 2004-06-24 | 2006-11-02 | Novartis Vaccines And Diagnostics Inc. | Small molecule immunopotentiators and assays for their detection |
WO2006007710A2 (en) * | 2004-07-20 | 2006-01-26 | Vasogen Ireland Limited | Acute inflammatory condition treatment |
US20060210644A1 (en) * | 2004-12-16 | 2006-09-21 | Bruce Levin | Materials, methods, and devices for treatment of arthropathies and spondylopathies |
US20090232834A1 (en) * | 2005-07-18 | 2009-09-17 | Al-Harbi Saleh A | Methods and Agents to Treat Autoimmune Diseases |
US8518649B2 (en) * | 2007-04-04 | 2013-08-27 | {hacek over (S)}árka O. Southern | Systems and methods for analyzing persistent homeostatic perturbations |
US8951561B2 (en) * | 2007-08-06 | 2015-02-10 | Duke University | Methods and systems for treating cell proliferation disorders using plasmonics enhanced photospectral therapy (PEPST) and exciton-plasmon enhanced phototherapy (EPEP) |
US9358292B2 (en) | 2007-04-08 | 2016-06-07 | Immunolight, Llc | Methods and systems for treating cell proliferation disorders |
WO2015195896A1 (en) | 2014-06-19 | 2015-12-23 | Immunolight, Llc | Methods and systems for treating cell proliferation disorders with psoralen derivatives |
US20090104212A1 (en) * | 2007-08-06 | 2009-04-23 | Immunolight | Methods and systems for treating cell proliferation disorders using two-photon simultaneous absorption |
KR101322247B1 (ko) * | 2007-09-06 | 2013-10-25 | 삼성전자주식회사 | 진공청소기용 흡입브러시 및 그 높이조절방법 |
CA3095369C (en) | 2008-04-04 | 2023-09-26 | Immunolight, Llc | Non-invasive systems and methods for in-situ photobiomodulation |
EP2729175B1 (de) | 2011-07-08 | 2021-12-01 | Duke University | System zur lichtstimulation in einem medium |
ITMI20131667A1 (it) * | 2013-10-09 | 2015-04-10 | Ind Paolo Gobbi Frattini | Metodo per pre-trattare le cellule ematiche prima della separazione. |
WO2015112850A2 (en) | 2014-01-23 | 2015-07-30 | Wenle Xia | Use of psoralen derivatives and combination therapy for treatment of cell proliferation disorders |
Family Cites Families (31)
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DE1068428C2 (de) | 1957-05-21 | 1960-04-21 | Hermann Dr Med Jentjens | Verfahren und Einrichtung zur Herstellung von oxygeniertrm Blut |
US3715430A (en) * | 1969-08-04 | 1973-02-06 | E Ryan | Purified oxygen gas containing ozone and higher oxygen polymers |
US3925344A (en) | 1973-04-11 | 1975-12-09 | Community Blood Council | Plasma protein substitute |
US4061736A (en) | 1975-02-02 | 1977-12-06 | Alza Corporation | Pharmaceutically acceptable intramolecularly cross-linked, stromal-free hemoglobin |
US4473496A (en) | 1981-09-14 | 1984-09-25 | The United States Of America As Represented By The Secretary Of The Army | Intramolecularly crosslinked hemoglobin |
JPS58198466A (ja) | 1982-05-12 | 1983-11-18 | Teijin Ltd | 5−チアプロスタグランジン類およびその製造法 |
FR2528848A1 (fr) | 1982-06-16 | 1983-12-23 | Sanofi Sa | Nouveau derive de thieno-pyridone, son procede de preparation et son application therapeutique |
US4613322A (en) * | 1982-12-08 | 1986-09-23 | Edelson Richard Leslie | Method and system for externally treating the blood |
US4529719A (en) | 1983-05-04 | 1985-07-16 | Tye Ross W | Modified crosslinked stroma-free tetrameric hemoglobin |
US4695647A (en) | 1984-03-22 | 1987-09-22 | Drug Science Foundation | Aromatic derivatives of 13-azaprostanoic acid |
US4659726A (en) | 1984-04-19 | 1987-04-21 | Kanebo, Ltd. | Novel 4,5-Bis (4-methoxyphenyl)-2-(pyrrol-2-yl) thiazoles and pharmaceutical composition containing the same |
US4600531A (en) | 1984-06-27 | 1986-07-15 | University Of Iowa Research Foundation | Production of alpha-alpha cross-linked hemoglobins in high yield |
DD249143A3 (de) * | 1985-03-20 | 1987-09-02 | Ilmenau Tech Hochschule | Vorrichtung zur physiologisch-therapeutisch wirksamen optischen bestrahlung koerpereigenen venenblutes |
US4584130A (en) | 1985-03-29 | 1986-04-22 | University Of Maryland | Intramolecularly cross-linked hemoglobin and method of preparation |
US4632980A (en) * | 1985-04-03 | 1986-12-30 | Immunologics | Ozone decontamination of blood and blood products |
US5194590A (en) | 1986-06-20 | 1993-03-16 | Northfield Laboratories, Inc. | Acellular red blood cell substitute |
US4826811A (en) | 1986-06-20 | 1989-05-02 | Northfield Laboratories, Inc. | Acellular red blood cell substitute |
DE8704467U1 (de) * | 1987-01-15 | 1988-05-26 | Quarzlampenfabrik Dr.-Ing. Felix W. Mueller Gmbh & Co Kg, 4300 Essen, De | |
US4838852A (en) * | 1987-03-27 | 1989-06-13 | Therakos, Inc. | Active specific immune suppression |
GB8710598D0 (en) | 1987-05-05 | 1987-06-10 | Star Medical Diagnostics Ltd | Hemoglobin based blood substitute |
GB8711614D0 (en) | 1987-05-16 | 1987-06-24 | Medical Res Council | Proteins |
EP0339924B1 (de) * | 1988-04-29 | 1995-03-29 | Medizone International, Inc. | Vorrichtung für die gesteuerte Generierung und Verabreichung von Ozon |
US4983637A (en) | 1988-06-24 | 1991-01-08 | Stephen Herman | Method for treating viral infection of HIV |
WO1992010198A1 (en) * | 1990-12-06 | 1992-06-25 | Johnson & Johnson Research Pty Limited | Immunotherapeutic agents, compositions and methods |
US5250665A (en) | 1991-05-31 | 1993-10-05 | The University Of Toronto Innovations Foundation | Specifically β-β cross-linked hemoglobins and method of preparation |
US5591457A (en) | 1992-02-07 | 1997-01-07 | Vasogen Inc | Method of inhibiting the aggregation of blood platelets and stimulating the immune systems of a human |
AU3506293A (en) | 1992-02-07 | 1993-09-03 | Anthony Ernest Bolton | Method of inhibiting the aggregation of blood platelets |
US5980954A (en) | 1992-02-07 | 1999-11-09 | Vasogen Ireland Limited | Treatment of autoimmune diseases |
AU681999B2 (en) | 1992-02-07 | 1997-09-18 | Vasogen Ireland Limited | Method of increasing the concentration of nitric oxide in blood |
NZ306395A (en) | 1995-05-05 | 2000-02-28 | Vasogen Inc | Treatment of blood to remove symptoms of vascular disorders by elevation of temperature, ultraviolet radiation or treatment with an oxidative environment |
US6264646B1 (en) | 1998-11-13 | 2001-07-24 | Vasogen Ireland Limited | Method for preventing and reversing atherosclerosis in mammals |
-
1996
- 1996-11-22 US US08/754,348 patent/US5980954A/en not_active Expired - Fee Related
-
1997
- 1997-08-11 JP JP51019398A patent/JP3883013B2/ja not_active Expired - Fee Related
- 1997-08-11 AU AU38442/97A patent/AU724265B2/en not_active Ceased
- 1997-08-11 AT AT97935400T patent/ATE237339T1/de not_active IP Right Cessation
- 1997-08-11 EP EP97935400A patent/EP0920322B9/de not_active Expired - Lifetime
- 1997-08-11 DK DK97935400T patent/DK0920322T3/da active
- 1997-08-11 DE DE69721006T patent/DE69721006T2/de not_active Expired - Fee Related
- 1997-08-11 WO PCT/CA1997/000564 patent/WO1998007436A1/en active IP Right Grant
- 1997-08-11 PT PT97935400T patent/PT920322E/pt unknown
- 1997-08-11 NZ NZ334635A patent/NZ334635A/xx unknown
- 1997-08-11 CA CA002263911A patent/CA2263911C/en not_active Expired - Fee Related
- 1997-08-11 ES ES97935400T patent/ES2199367T3/es not_active Expired - Lifetime
-
1999
- 1999-01-05 US US09/225,353 patent/US6569467B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
NZ334635A (en) | 2000-08-25 |
AU724265B2 (en) | 2000-09-14 |
EP0920322B9 (de) | 2003-10-29 |
WO1998007436A1 (en) | 1998-02-26 |
DE69721006T2 (de) | 2004-01-22 |
CA2263911C (en) | 2007-01-16 |
AU3844297A (en) | 1998-03-06 |
JP3883013B2 (ja) | 2007-02-21 |
PT920322E (pt) | 2003-11-28 |
US5980954A (en) | 1999-11-09 |
US6569467B1 (en) | 2003-05-27 |
EP0920322B1 (de) | 2003-04-16 |
JP2000517302A (ja) | 2000-12-26 |
EP0920322A1 (de) | 1999-06-09 |
CA2263911A1 (en) | 1998-02-26 |
ATE237339T1 (de) | 2003-05-15 |
DK0920322T3 (da) | 2003-08-04 |
ES2199367T3 (es) | 2004-02-16 |
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