DE69625920T2 - Expressionsnachweis durch hybridisierung an oligonukleotidarrays hoher belegungsdichte - Google Patents

Expressionsnachweis durch hybridisierung an oligonukleotidarrays hoher belegungsdichte

Info

Publication number: DE69625920T2
Authority: DE; Germany
Prior art keywords: nucleic acids; array; rna transcripts; oligonucleotide probes; oligonucleotid
Prior art date: 1995-09-15
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE69625920T

Other languages

English (en)

Other versions

DE69625920D1 (de

Inventor

J Lockhart

L Brown

Gordon Wong

Mark Chee

R Gingeras

P Mittmann

J Lipshutz

P Fodor

Chunwei Wang

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Affymetrix Inc

Original Assignee

Affymetrix Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-09-15

Filing date

1996-09-13

Publication date

2003-10-30

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24108589&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69625920(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1996-09-13 Application filed by Affymetrix Inc filed Critical Affymetrix Inc

2003-02-27 Publication of DE69625920D1 publication Critical patent/DE69625920D1/de

2003-10-30 Application granted granted Critical

2003-10-30 Publication of DE69625920T2 publication Critical patent/DE69625920T2/de

2016-09-14 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

238000001514 detection method Methods 0.000 title 1
238000009396 hybridization Methods 0.000 title 1
108020004707 nucleic acids Proteins 0.000 abstract 8
150000007523 nucleic acids Chemical class 0.000 abstract 8
102000039446 nucleic acids Human genes 0.000 abstract 8
108091034117 Oligonucleotide Proteins 0.000 abstract 4
108020005187 Oligonucleotide Probes Proteins 0.000 abstract 3
JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 abstract 3
238000000034 method Methods 0.000 abstract 3
239000002751 oligonucleotide probe Substances 0.000 abstract 3
239000000523 sample Substances 0.000 abstract 3
230000000295 complement effect Effects 0.000 abstract 2
108090000623 proteins and genes Proteins 0.000 abstract 2
238000012544 monitoring process Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
- G01N15/1433—

DE69625920T 1995-09-15 1996-09-13 Expressionsnachweis durch hybridisierung an oligonukleotidarrays hoher belegungsdichte Expired - Lifetime DE69625920T2 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/529,115 US6040138A (en)	1995-09-15	1995-09-15	Expression monitoring by hybridization to high density oligonucleotide arrays
PCT/US1996/014839 WO1997010365A1 (en)	1995-09-15	1996-09-13	Expression monitoring by hybridization to high density oligonucleotide arrays

Publications (2)

Publication Number	Publication Date
DE69625920D1 DE69625920D1 (de)	2003-02-27
DE69625920T2 true DE69625920T2 (de)	2003-10-30

Family

ID=24108589

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE69625920T Expired - Lifetime DE69625920T2 (de)	1995-09-15	1996-09-13	Expressionsnachweis durch hybridisierung an oligonukleotidarrays hoher belegungsdichte

Country Status (9)

Country	Link
US (6)	US6040138A (de)
EP (1)	EP0853679B1 (de)
JP (1)	JPH11512293A (de)
AT (1)	ATE231559T1 (de)
AU (1)	AU7073496A (de)
CA (1)	CA2232047A1 (de)
DE (1)	DE69625920T2 (de)
HK (1)	HK1015416A1 (de)
WO (1)	WO1997010365A1 (de)

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1995
- 1995-09-15 US US08/529,115 patent/US6040138A/en not_active Expired - Lifetime
1996
- 1996-09-13 DE DE69625920T patent/DE69625920T2/de not_active Expired - Lifetime
- 1996-09-13 EP EP96931598A patent/EP0853679B1/de not_active Revoked
- 1996-09-13 JP JP9512174A patent/JPH11512293A/ja not_active Withdrawn
- 1996-09-13 WO PCT/US1996/014839 patent/WO1997010365A1/en active IP Right Grant
- 1996-09-13 AT AT96931598T patent/ATE231559T1/de not_active IP Right Cessation
- 1996-09-13 AU AU70734/96A patent/AU7073496A/en not_active Abandoned
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1998
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- 1998-12-28 HK HK98115957A patent/HK1015416A1/xx not_active IP Right Cessation
2001
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2004
- 2004-11-23 US US10/998,518 patent/US20050158746A1/en not_active Abandoned
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Publication number	Publication date
US20050202500A1 (en)	2005-09-15
US20020012940A1 (en)	2002-01-31
CA2232047A1 (en)	1997-03-20
US20030215841A1 (en)	2003-11-20
EP0853679A1 (de)	1998-07-22
US6548257B2 (en)	2003-04-15
DE69625920D1 (de)	2003-02-27
US6410229B1 (en)	2002-06-25
US6040138A (en)	2000-03-21
US20050158746A1 (en)	2005-07-21
EP0853679B1 (de)	2003-01-22
AU7073496A (en)	1997-04-01
ATE231559T1 (de)	2003-02-15
JPH11512293A (ja)	1999-10-26
WO1997010365A1 (en)	1997-03-20
HK1015416A1 (en)	1999-10-15
US6927032B2 (en)	2005-08-09

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