DE69622936T2 - Vermittler, geeignet für die elektrochemischr Regenierung von NADH, NADPH oder deren Analogen - Google Patents

Vermittler, geeignet für die elektrochemischr Regenierung von NADH, NADPH oder deren Analogen

Info

Publication number
DE69622936T2
DE69622936T2 DE69622936T DE69622936T DE69622936T2 DE 69622936 T2 DE69622936 T2 DE 69622936T2 DE 69622936 T DE69622936 T DE 69622936T DE 69622936 T DE69622936 T DE 69622936T DE 69622936 T2 DE69622936 T2 DE 69622936T2
Authority
DE
Germany
Prior art keywords
nadh
nadph
analogues
electrochemical regeneration
mediator suitable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69622936T
Other languages
English (en)
Other versions
DE69622936D1 (de
Inventor
Michael L Bloczynski
Paul F Corey
Yingping Deng
Alison J Murray
Metthew K Musho
Hans-Ulrich Siegmund
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Bayer Corp
Original Assignee
Bayer AG
Bayer Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG, Bayer Corp filed Critical Bayer AG
Publication of DE69622936D1 publication Critical patent/DE69622936D1/de
Application granted granted Critical
Publication of DE69622936T2 publication Critical patent/DE69622936T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/004—Enzyme electrodes mediator-assisted
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01M—PROCESSES OR MEANS, e.g. BATTERIES, FOR THE DIRECT CONVERSION OF CHEMICAL ENERGY INTO ELECTRICAL ENERGY
    • H01M4/00—Electrodes
    • H01M4/86—Inert electrodes with catalytic activity, e.g. for fuel cells
    • H01M4/90—Selection of catalytic material
    • H01M4/9008—Organic or organo-metallic compounds
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01M—PROCESSES OR MEANS, e.g. BATTERIES, FOR THE DIRECT CONVERSION OF CHEMICAL ENERGY INTO ELECTRICAL ENERGY
    • H01M8/00—Fuel cells; Manufacture thereof
    • H01M8/16—Biochemical fuel cells, i.e. cells in which microorganisms function as catalysts
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E60/00—Enabling technologies; Technologies with a potential or indirect contribution to GHG emissions mitigation
    • Y02E60/30—Hydrogen technology
    • Y02E60/50—Fuel cells
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/817—Enzyme or microbe electrode
DE69622936T 1995-06-06 1996-05-24 Vermittler, geeignet für die elektrochemischr Regenierung von NADH, NADPH oder deren Analogen Expired - Lifetime DE69622936T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/471,745 US5520786A (en) 1995-06-06 1995-06-06 Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof

Publications (2)

Publication Number Publication Date
DE69622936D1 DE69622936D1 (de) 2002-09-19
DE69622936T2 true DE69622936T2 (de) 2003-01-02

Family

ID=23872830

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69622936T Expired - Lifetime DE69622936T2 (de) 1995-06-06 1996-05-24 Vermittler, geeignet für die elektrochemischr Regenierung von NADH, NADPH oder deren Analogen

Country Status (6)

Country Link
US (1) US5520786A (de)
EP (1) EP0747984B1 (de)
JP (1) JP3831008B2 (de)
AU (1) AU692387B2 (de)
CA (1) CA2177753C (de)
DE (1) DE69622936T2 (de)

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EP1098193B1 (de) 1998-07-16 2005-12-21 Sapporo Immuno Diagnostic Laboratory Verfahren zum bestimmen von l-phenylalanin und ein l-phenylalaninsensor
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US20030113606A1 (en) * 2001-04-13 2003-06-19 Rosalyn Ritts Biocompatible membranes of block copolymers and fuel cells produced therewith
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US20030087141A1 (en) * 2001-04-13 2003-05-08 Sun Hoi-Cheong Steve Dual membrane fuel cell
US20030031911A1 (en) * 2001-04-13 2003-02-13 Rosalyn Ritts Biocompatible membranes and fuel cells produced therewith
EP1867732B1 (de) * 2001-09-14 2015-01-28 Bayer HealthCare LLC Reagenzien, Verfahren und Vorrichtungen zum Nachweis von Analyten
US7163616B2 (en) * 2001-09-14 2007-01-16 Bayer Corporation Reagents and methods for detecting analytes, and devices comprising reagents for detecting analytes
CA2466133A1 (en) * 2001-11-02 2003-05-15 Rice University Recycling system for manipulation of intracellular nadh availability
KR100483624B1 (ko) * 2002-11-01 2005-04-19 학교법인 건국대학교 환경 쇼크를 이용한 미생물 연료전지의 전류량 제어 방법
US7638228B2 (en) * 2002-11-27 2009-12-29 Saint Louis University Enzyme immobilization for use in biofuel cells and sensors
CA2455669A1 (en) * 2003-02-04 2004-08-04 Bayer Healthcare, Llc Method and test strip for determining glucose in blood
WO2005040407A1 (en) * 2003-10-24 2005-05-06 Bayer Healthcare Llc Enzymatic electrochemical biosensor
US8859151B2 (en) 2003-11-05 2014-10-14 St. Louis University Immobilized enzymes in biocathodes
US7244610B2 (en) * 2003-11-14 2007-07-17 Rice University Aerobic succinate production in bacteria
RU2006132051A (ru) * 2004-02-06 2008-03-20 БАЙЕР ХЕЛТКЭР ЭлЭлСи (US) Окисляемые соединения в качестве внутреннего стандарта для биосенсоров и способ их применения
CN101073000B (zh) * 2004-10-12 2012-01-11 拜尔健康护理有限责任公司 扩散阻挡层中的浓度测定
ATE530906T1 (de) * 2004-12-13 2011-11-15 Bayer Healthcare Llc Verfahren zur unterscheidung zwischen einen gemeinsamen analyten enthaltenden blut- und kontrollösungen
CA2603542C (en) 2005-04-08 2014-01-14 Bayer Healthcare Llc Oxidizable species as an internal reference in control solutions for biosensors
US8435773B2 (en) * 2005-05-10 2013-05-07 Board Of Trustees Of Michigan State University Customizable and renewable nanostructured interface for bioelectronic applications
US9406959B2 (en) * 2005-05-10 2016-08-02 Board Of Trustees Of Michigan State University Electrobiocatalytic reactors having reversible bioelectronic interfaces and methods and devices related thereto
AR054851A1 (es) 2005-07-20 2007-07-18 Bayer Healthcare Llc Amperometria regulada
US8404100B2 (en) 2005-09-30 2013-03-26 Bayer Healthcare Llc Gated voltammetry
WO2007084249A2 (en) 2005-11-02 2007-07-26 St.Louis University Direct electron transfer using enzymes in bioanodes, biocathodes, and biofuel cells
US20090176162A1 (en) * 2006-04-07 2009-07-09 Ivan Exnar Lithium rechargeable electrochemical cell
BRPI0717430A2 (pt) 2006-09-22 2013-11-12 Bayer Healthcare Llc Sistema de biossensor tendo estabilidade e desempenho de hematócritos maiores
EP2083674B1 (de) 2006-10-24 2018-03-07 Ascensia Diabetes Care Holdings AG Nachwirkungsstrommessung
CA2700507C (en) 2007-09-24 2018-05-29 Bayer Healthcare Llc Multi-region and potential test sensors, methods, and systems
WO2009076302A1 (en) * 2007-12-10 2009-06-18 Bayer Healthcare Llc Control markers for auto-detection of control solution and methods of use
EP2222866A1 (de) 2007-12-10 2010-09-01 Bayer HealthCare LLC Reagentien und verfahren zum nachweis von analyten
EP2229590B1 (de) 2007-12-10 2018-11-21 Ascensia Diabetes Care Holdings AG Verfahren zur herstellung eines 3-phenylimino-3h-phenothiazin- oder 3-phenylimino-3h-phenoxazin-mediators
US8252523B2 (en) 2007-12-10 2012-08-28 Bayer Healthcare Llc Porous particle reagent compositions
US8008037B2 (en) 2008-03-27 2011-08-30 Roche Diagnostics Operations, Inc. Matrix composition with alkylphenazine quaternary salt and a nitrosoaniline
US20090305317A1 (en) * 2008-06-05 2009-12-10 Brauer Jacob S User interface for testing device
US8679772B2 (en) * 2008-06-06 2014-03-25 Agency For Science, Technology And Research Immunoassay
WO2010006253A1 (en) 2008-07-10 2010-01-14 Bayer Healthcare Llc Systems and methods including amperometric and voltammetric duty cycles
EP2373805B1 (de) 2008-12-08 2015-11-04 Bayer HealthCare LLC Niedriggesamtsalz-reagenszusammensetzungen und systeme für biosensoren
WO2010141359A2 (en) * 2009-06-01 2010-12-09 Bayer Healthcare Llc Redox molecules and methods of making the same
JP5782044B2 (ja) 2009-11-10 2015-09-24 バイエル・ヘルスケア・エルエルシーＢａｙｅｒ ＨｅａｌｔｈＣａｒｅＬＬＣ バイオセンサ用の充填量不足認識システム
US20120252046A1 (en) 2009-12-17 2012-10-04 Bayer Healthcare Llc Transdermal systems, devices, and methods for biological analysis
US9354226B2 (en) 2009-12-17 2016-05-31 Ascensia Diabetes Care Holdings Ag Transdermal systems, devices, and methods to optically analyze an analyte
US9233788B2 (en) 2010-01-22 2016-01-12 Bayer Healthcare Llc Biosensor desiccant system having enhanced measurement performance
WO2011150155A1 (en) 2010-05-28 2011-12-01 Bayer Healthcare Llc Polymer bonded redox molecules and methods of making the same
WO2012040599A1 (en) 2010-09-23 2012-03-29 Bayer Healthcare Llc Radically polymerizable phenothiazine macromonomer for use in the coating of medical devices
TWI565943B (zh) 2011-07-22 2017-01-11 拜耳保健公司 具有增進測量性能之生物感測器乾燥劑系統
KR101355127B1 (ko) * 2011-09-30 2014-01-29 주식회사 아이센스 전기화학적 바이오센서용 산화환원반응 시약조성물 및 이를 포함하는 바이오센서
US20130284609A1 (en) * 2012-04-30 2013-10-31 Lifescan Scotland Limited Enzymatic electrochemical-based sensors with nad polymeric coenzyme
JP6427110B2 (ja) 2013-01-28 2018-11-21 エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト アスペルギルスニガー由来の新規グルコース酸化酵素
CN113058621B (zh) * 2019-12-12 2022-02-15 中国科学院大连化学物理研究所 还原型辅酶及其类似物再生催化剂以及制备方法、应用
AU2020410741B2 (en) 2019-12-26 2024-04-18 Sogang University Research & Business Development Foundation Novel organic electron transfer mediator and device comprising same

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US4490464A (en) * 1981-04-08 1984-12-25 Gorton Lo G Electrode for the electrochemical regeneration of coenzyme, a method of making said electrode, and the use thereof
GB8424709D0 (en) * 1984-10-01 1984-11-07 Minnesota Mining & Mfg Azine redox dyes and leuco azine dyes
US5192631A (en) * 1987-03-18 1993-03-09 Dai Nippon Insatsu Kabushiki Kaisha Variable electroconductivity material
IL102930A (en) * 1992-08-25 1997-03-18 Yissum Res Dev Co Electrobiochemical analytical method and electrodes
US5393615A (en) * 1994-02-03 1995-02-28 Miles Inc. Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof
JPH08304329A (ja) * 1995-05-09 1996-11-22 Kdk Corp 多孔性膜を使用したバイオセンサー、および該多孔性膜の 製造方法

Also Published As

Publication number Publication date
EP0747984A3 (de) 1997-07-16
DE69622936D1 (de) 2002-09-19
US5520786A (en) 1996-05-28
JP3831008B2 (ja) 2006-10-11
CA2177753A1 (en) 1996-12-07
AU692387B2 (en) 1998-06-04
CA2177753C (en) 2004-07-27
EP0747984A2 (de) 1996-12-11
AU5475096A (en) 1996-12-19
EP0747984B1 (de) 2002-08-14
JPH08334490A (ja) 1996-12-17

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