DE69622936D1 - Vermittler, geeignet für die elektrochemischr Regenierung von NADH, NADPH oder deren Analogen - Google Patents

Vermittler, geeignet für die elektrochemischr Regenierung von NADH, NADPH oder deren Analogen

Info

Publication number
DE69622936D1
DE69622936D1 DE69622936T DE69622936T DE69622936D1 DE 69622936 D1 DE69622936 D1 DE 69622936D1 DE 69622936 T DE69622936 T DE 69622936T DE 69622936 T DE69622936 T DE 69622936T DE 69622936 D1 DE69622936 D1 DE 69622936D1
Authority
DE
Germany
Prior art keywords
nadh
nadph
analogs
electrochemical regeneration
electrochemical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69622936T
Other languages
English (en)
Other versions
DE69622936T2 (de
Inventor
Michael L Bloczynski
Paul F Corey
Yingping Deng
Alison J Murray
Metthew K Musho
Hans-Ulrich Siegmund
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Bayer Corp
Original Assignee
Bayer AG
Bayer Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG, Bayer Corp filed Critical Bayer AG
Application granted granted Critical
Publication of DE69622936D1 publication Critical patent/DE69622936D1/de
Publication of DE69622936T2 publication Critical patent/DE69622936T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001Enzyme electrodes
    • C12Q1/004Enzyme electrodes mediator-assisted
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01MPROCESSES OR MEANS, e.g. BATTERIES, FOR THE DIRECT CONVERSION OF CHEMICAL ENERGY INTO ELECTRICAL ENERGY
    • H01M4/00Electrodes
    • H01M4/86Inert electrodes with catalytic activity, e.g. for fuel cells
    • H01M4/90Selection of catalytic material
    • H01M4/9008Organic or organo-metallic compounds
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01MPROCESSES OR MEANS, e.g. BATTERIES, FOR THE DIRECT CONVERSION OF CHEMICAL ENERGY INTO ELECTRICAL ENERGY
    • H01M8/00Fuel cells; Manufacture thereof
    • H01M8/16Biochemical fuel cells, i.e. cells in which microorganisms function as catalysts
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02EREDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E60/00Enabling technologies; Technologies with a potential or indirect contribution to GHG emissions mitigation
    • Y02E60/30Hydrogen technology
    • Y02E60/50Fuel cells
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/817Enzyme or microbe electrode
DE69622936T 1995-06-06 1996-05-24 Vermittler, geeignet für die elektrochemischr Regenierung von NADH, NADPH oder deren Analogen Expired - Lifetime DE69622936T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/471,745 US5520786A (en) 1995-06-06 1995-06-06 Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof

Publications (2)

Publication Number Publication Date
DE69622936D1 true DE69622936D1 (de) 2002-09-19
DE69622936T2 DE69622936T2 (de) 2003-01-02

Family

ID=23872830

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69622936T Expired - Lifetime DE69622936T2 (de) 1995-06-06 1996-05-24 Vermittler, geeignet für die elektrochemischr Regenierung von NADH, NADPH oder deren Analogen

Country Status (6)

Country Link
US (1) US5520786A (de)
EP (1) EP0747984B1 (de)
JP (1) JP3831008B2 (de)
AU (1) AU692387B2 (de)
CA (1) CA2177753C (de)
DE (1) DE69622936T2 (de)

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EP1098193B1 (de) 1998-07-16 2005-12-21 Sapporo Immuno Diagnostic Laboratory Verfahren zum bestimmen von l-phenylalanin und ein l-phenylalaninsensor
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US20030113606A1 (en) * 2001-04-13 2003-06-19 Rosalyn Ritts Biocompatible membranes of block copolymers and fuel cells produced therewith
US20030129469A1 (en) * 2001-04-13 2003-07-10 Sun Hoi-Cheong Steve Fuel cell with fuel concentrate metering
US20030049511A1 (en) * 2001-04-13 2003-03-13 Rosalyn Ritts Stabilized biocompatible membranes of block copolymers and fuel cells produced therewith
US20030031911A1 (en) * 2001-04-13 2003-02-13 Rosalyn Ritts Biocompatible membranes and fuel cells produced therewith
US7163616B2 (en) * 2001-09-14 2007-01-16 Bayer Corporation Reagents and methods for detecting analytes, and devices comprising reagents for detecting analytes
EP1867732B1 (de) * 2001-09-14 2015-01-28 Bayer HealthCare LLC Reagenzien, Verfahren und Vorrichtungen zum Nachweis von Analyten
EP1483378B1 (de) * 2001-11-02 2013-01-02 Rice University Recycling-system zur manipulation intrazellulärer nadh-verfügbarkeit
KR100483624B1 (ko) * 2002-11-01 2005-04-19 학교법인 건국대학교 환경 쇼크를 이용한 미생물 연료전지의 전류량 제어 방법
US7638228B2 (en) 2002-11-27 2009-12-29 Saint Louis University Enzyme immobilization for use in biofuel cells and sensors
CA2455669A1 (en) * 2003-02-04 2004-08-04 Bayer Healthcare, Llc Method and test strip for determining glucose in blood
CA2543010A1 (en) 2003-10-24 2005-05-06 Bayer Healthcare Llc Enzymatic electrochemical biosensor
US8859151B2 (en) 2003-11-05 2014-10-14 St. Louis University Immobilized enzymes in biocathodes
US7244610B2 (en) * 2003-11-14 2007-07-17 Rice University Aerobic succinate production in bacteria
BRPI0507376A (pt) * 2004-02-06 2007-07-10 Bayer Healthcare Llc espécie oxidável como uma referência interna para biossensores e método de uso
WO2006042304A1 (en) * 2004-10-12 2006-04-20 Bayer Healthcare Llc Concentration determination in a diffusion barrier layer
CN101076728A (zh) * 2004-12-13 2007-11-21 拜尔保健有限公司 区分含有共同的分析物的血液和对照溶液的方法
CN102778487B (zh) 2005-04-08 2015-02-18 拜尔保健有限公司 作为用于生物传感器的对照溶液的内部参考的可氧化的物质
US9406959B2 (en) * 2005-05-10 2016-08-02 Board Of Trustees Of Michigan State University Electrobiocatalytic reactors having reversible bioelectronic interfaces and methods and devices related thereto
US8435773B2 (en) * 2005-05-10 2013-05-07 Board Of Trustees Of Michigan State University Customizable and renewable nanostructured interface for bioelectronic applications
AU2006272909B2 (en) 2005-07-20 2013-02-07 Bayer Healthcare Llc Gated amperometry
KR101477815B1 (ko) 2005-09-30 2015-01-02 바이엘 헬스케어 엘엘씨 게이트형 전압 전류 측정법
WO2007084249A2 (en) 2005-11-02 2007-07-26 St.Louis University Direct electron transfer using enzymes in bioanodes, biocathodes, and biofuel cells
EP2360758B1 (de) * 2006-04-07 2014-02-26 Dow Global Technologies LLC Wiederaufladbare elektrochemische lithiumzelle
EP3543348B1 (de) 2006-09-22 2020-11-18 Ascensia Diabetes Care Holdings AG Biosensorsystem mit verbesserter stabilität und hämatokrit-ausführung
BRPI0717620A2 (pt) 2006-10-24 2013-10-22 Bayer Healthcare Llc Amperometria de decaimento transitório
EP3660499A1 (de) 2007-09-24 2020-06-03 Ascensia Diabetes Care Holdings AG Mehrteilige und potentialtestsensoren, verfahren und systeme
US20090145775A1 (en) 2007-12-10 2009-06-11 Bayer Healthcare Llc Reagents and methods for detecting analytes
WO2009076302A1 (en) 2007-12-10 2009-06-18 Bayer Healthcare Llc Control markers for auto-detection of control solution and methods of use
ES2664574T3 (es) 2007-12-10 2018-04-20 Ascensia Diabetes Care Holdings Ag Composiciones reactivas de partículas porosas, dispositivos y métodos para biosensores
WO2009076268A1 (en) 2007-12-10 2009-06-18 Bayer Healthcare Llc Process of making 3-phenylimino-3h-phenothiazine or 3-phenylimino-3h-phenoxazine mediator
US8008037B2 (en) 2008-03-27 2011-08-30 Roche Diagnostics Operations, Inc. Matrix composition with alkylphenazine quaternary salt and a nitrosoaniline
US20090305317A1 (en) * 2008-06-05 2009-12-10 Brauer Jacob S User interface for testing device
WO2009148406A1 (en) * 2008-06-06 2009-12-10 Agency For Science Technology And Research Immunoassay
US8262899B2 (en) 2008-07-10 2012-09-11 Bayer Healthcare Llc Systems and methods including amperometric and voltammetric duty cycles
ES2555215T3 (es) 2008-12-08 2015-12-29 Bayer Healthcare Llc Composiciones de reactivo de bajo contenido salino total y sistemas para biosensores
US8283347B2 (en) * 2009-06-01 2012-10-09 Bayer Healthcare Llc Redox molecules and methods of making the same
EP2499483B1 (de) 2009-11-10 2021-03-17 Ascensia Diabetes Care Holdings AG Verfahren und Biosensor zur Berurteilung des Volumens einer Blutprobe
WO2011075575A1 (en) 2009-12-17 2011-06-23 Bayer Healthcare Llc Transdermal systems, devices, and methods to optically analyze an analyte
WO2011084607A1 (en) 2009-12-17 2011-07-14 Bayer Healthcare Llc Transdermal systems, devices, and methods for biological analysis
US9233788B2 (en) 2010-01-22 2016-01-12 Bayer Healthcare Llc Biosensor desiccant system having enhanced measurement performance
US8742063B2 (en) 2010-05-28 2014-06-03 Bayer Healthcare Llc Polymer bonded redox molecules and methods of making the same
US8877344B2 (en) 2010-09-23 2014-11-04 Bayer Healthcare Llc Radically polymerizable phenothiazine macromonomer for use in the coating of medical devices
TWI565943B (zh) 2011-07-22 2017-01-11 拜耳保健公司 具有增進測量性能之生物感測器乾燥劑系統
KR101355127B1 (ko) * 2011-09-30 2014-01-29 주식회사 아이센스 전기화학적 바이오센서용 산화환원반응 시약조성물 및 이를 포함하는 바이오센서
US20130284609A1 (en) * 2012-04-30 2013-10-31 Lifescan Scotland Limited Enzymatic electrochemical-based sensors with nad polymeric coenzyme
WO2014114810A1 (en) 2013-01-28 2014-07-31 Roche Diagnostics Gmbh Novel glucose oxidases derived from aspergillus niger
CN113058621B (zh) * 2019-12-12 2022-02-15 中国科学院大连化学物理研究所 还原型辅酶及其类似物再生催化剂以及制备方法、应用
JP7411094B2 (ja) 2019-12-26 2024-01-10 アイセンス,インコーポレーテッド 新規な有機電子伝達媒介体およびこれを含む装置

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0076266B1 (de) * 1981-04-08 1988-11-09 GORTON, Lo Elektrode zum elektrochemischen regenerieren von koenzymen, verfahren zur herstellung dieser elektrode sowie deren verwendung
GB8424709D0 (en) * 1984-10-01 1984-11-07 Minnesota Mining & Mfg Azine redox dyes and leuco azine dyes
US5192631A (en) * 1987-03-18 1993-03-09 Dai Nippon Insatsu Kabushiki Kaisha Variable electroconductivity material
IL102930A (en) * 1992-08-25 1997-03-18 Yissum Res Dev Co Electrobiochemical analytical method and electrodes
US5393615A (en) * 1994-02-03 1995-02-28 Miles Inc. Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof
JPH08304329A (ja) * 1995-05-09 1996-11-22 Kdk Corp 多孔性膜を使用したバイオセンサー、および該多孔性膜の 製造方法

Also Published As

Publication number Publication date
DE69622936T2 (de) 2003-01-02
CA2177753A1 (en) 1996-12-07
EP0747984A3 (de) 1997-07-16
EP0747984A2 (de) 1996-12-11
JPH08334490A (ja) 1996-12-17
AU692387B2 (en) 1998-06-04
JP3831008B2 (ja) 2006-10-11
US5520786A (en) 1996-05-28
CA2177753C (en) 2004-07-27
AU5475096A (en) 1996-12-19
EP0747984B1 (de) 2002-08-14

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