DE69523040D1 - Verfahren zur acridinium - markierung von mikropartikeln und anwendung in einem messinstrument - Google Patents
Verfahren zur acridinium - markierung von mikropartikeln und anwendung in einem messinstrumentInfo
- Publication number
- DE69523040D1 DE69523040D1 DE69523040T DE69523040T DE69523040D1 DE 69523040 D1 DE69523040 D1 DE 69523040D1 DE 69523040 T DE69523040 T DE 69523040T DE 69523040 T DE69523040 T DE 69523040T DE 69523040 D1 DE69523040 D1 DE 69523040D1
- Authority
- DE
- Germany
- Prior art keywords
- microparticle
- acridinium
- methods
- proteinaceous compound
- carboximide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000011859 microparticle Substances 0.000 title abstract 6
- 238000000034 method Methods 0.000 title abstract 5
- DZBUGLKDJFMEHC-UHFFFAOYSA-O acridine;hydron Chemical compound C1=CC=CC2=CC3=CC=CC=C3[NH+]=C21 DZBUGLKDJFMEHC-UHFFFAOYSA-O 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- WLLGXSLBOPFWQV-UHFFFAOYSA-N MGK 264 Chemical compound C1=CC2CC1C1C2C(=O)N(CC(CC)CCCC)C1=O WLLGXSLBOPFWQV-UHFFFAOYSA-N 0.000 abstract 2
- 238000010168 coupling process Methods 0.000 abstract 2
- ITMCEJHCFYSIIV-UHFFFAOYSA-M triflate Chemical compound [O-]S(=O)(=O)C(F)(F)F ITMCEJHCFYSIIV-UHFFFAOYSA-M 0.000 abstract 2
- DZBUGLKDJFMEHC-UHFFFAOYSA-N acridine Chemical class C1=CC=CC2=CC3=CC=CC=C3N=C21 DZBUGLKDJFMEHC-UHFFFAOYSA-N 0.000 abstract 1
- 230000001745 anti-biotin effect Effects 0.000 abstract 1
- 239000011248 coating agent Substances 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- 230000008878 coupling Effects 0.000 abstract 1
- 238000005859 coupling reaction Methods 0.000 abstract 1
- 239000012528 membrane Substances 0.000 abstract 1
- 239000011148 porous material Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/196,536 US5468649A (en) | 1994-02-15 | 1994-02-15 | Process for labeling acridinium to microparticles and application in an instrument |
PCT/US1995/001527 WO1995022059A1 (en) | 1994-02-15 | 1995-02-06 | Process for labelling acridinium to microparticles and application in an instrument |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69523040D1 true DE69523040D1 (de) | 2001-11-08 |
DE69523040T2 DE69523040T2 (de) | 2002-06-27 |
Family
ID=22725805
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69523040T Expired - Fee Related DE69523040T2 (de) | 1994-02-15 | 1995-02-06 | Verfahren zur acridinium - markierung von mikropartikeln und anwendung in einem messinstrument |
Country Status (9)
Country | Link |
---|---|
US (1) | US5468649A (de) |
EP (1) | EP0745223B1 (de) |
JP (1) | JP3580821B2 (de) |
AT (1) | ATE206523T1 (de) |
AU (1) | AU1744395A (de) |
CA (1) | CA2179310A1 (de) |
DE (1) | DE69523040T2 (de) |
ES (1) | ES2165907T3 (de) |
WO (1) | WO1995022059A1 (de) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1996022533A1 (en) * | 1995-01-18 | 1996-07-25 | First Medical, Inc. | Method for immobilizing haptens on a test article |
US5650334A (en) * | 1995-08-31 | 1997-07-22 | First Medical, Inc. | Fluorescent labelling compositions and methods for their use |
DE69737883T2 (de) | 1996-04-25 | 2008-03-06 | Bioarray Solutions Ltd. | Licht-regulierte, elektrokinetische zusammensetzung von partikeln an oberflächen |
US7262063B2 (en) | 2001-06-21 | 2007-08-28 | Bio Array Solutions, Ltd. | Directed assembly of functional heterostructures |
JP4377689B2 (ja) | 2001-10-15 | 2009-12-02 | バイオアレイ ソリューションズ リミテッド | 同時尋問及び酵素仲介検出による多型遺伝子座の複合分析 |
US6723851B2 (en) | 2001-10-31 | 2004-04-20 | Quest Diagnostics Investment Incorporated | Chemiluminescent compounds and use thereof |
US7872804B2 (en) | 2002-08-20 | 2011-01-18 | Illumina, Inc. | Encoded particle having a grating with variations in the refractive index |
US7900836B2 (en) | 2002-08-20 | 2011-03-08 | Illumina, Inc. | Optical reader system for substrates having an optically readable code |
US7619819B2 (en) | 2002-08-20 | 2009-11-17 | Illumina, Inc. | Method and apparatus for drug product tracking using encoded optical identification elements |
EP1535241A1 (de) | 2002-08-20 | 2005-06-01 | Cyvera Corporation | Auf einem beugungsgitter basierendes optisches identifikationselement |
US7923260B2 (en) | 2002-08-20 | 2011-04-12 | Illumina, Inc. | Method of reading encoded particles |
US7164533B2 (en) | 2003-01-22 | 2007-01-16 | Cyvera Corporation | Hybrid random bead/chip based microarray |
US7441703B2 (en) | 2002-08-20 | 2008-10-28 | Illumina, Inc. | Optical reader for diffraction grating-based encoded optical identification elements |
US7901630B2 (en) | 2002-08-20 | 2011-03-08 | Illumina, Inc. | Diffraction grating-based encoded microparticle assay stick |
US7508608B2 (en) | 2004-11-17 | 2009-03-24 | Illumina, Inc. | Lithographically fabricated holographic optical identification element |
WO2004025563A1 (en) | 2002-09-12 | 2004-03-25 | Cyvera Corporation | Diffraction grating-based encoded micro-particles for multiplexed experiments |
AU2003278827A1 (en) | 2002-09-12 | 2004-04-30 | Cyvera Corp. | Method and apparatus for labelling using diffraction grating-based encoded optical identification elements |
AU2003267192A1 (en) | 2002-09-12 | 2004-04-30 | Cyvera Corporation | Method and apparatus for aligning elongated microbeads in order to interrogate the same |
US7092160B2 (en) | 2002-09-12 | 2006-08-15 | Illumina, Inc. | Method of manufacturing of diffraction grating-based optical identification element |
AU2003274979A1 (en) | 2002-09-12 | 2004-04-30 | Cyvera Corporation | Chemical synthesis using diffraction grating-based encoded optical elements |
US20100255603A9 (en) | 2002-09-12 | 2010-10-07 | Putnam Martin A | Method and apparatus for aligning microbeads in order to interrogate the same |
AU2003298655A1 (en) | 2002-11-15 | 2004-06-15 | Bioarray Solutions, Ltd. | Analysis, secure access to, and transmission of array images |
WO2005029705A2 (en) | 2003-09-18 | 2005-03-31 | Bioarray Solutions, Ltd. | Number coding for identification of subtypes of coded types of solid phase carriers |
NZ546072A (en) * | 2003-09-22 | 2009-08-28 | Bioarray Solutions Ltd | Surface immobilized polyelectrolyte with multiple functional groups capable of covalently bonding to biomolecules |
WO2005042763A2 (en) | 2003-10-28 | 2005-05-12 | Bioarray Solutions Ltd. | Optimization of gene expression analysis using immobilized capture probes |
US7433123B2 (en) | 2004-02-19 | 2008-10-07 | Illumina, Inc. | Optical identification element having non-waveguide photosensitive substrate with diffraction grating therein |
US7848889B2 (en) | 2004-08-02 | 2010-12-07 | Bioarray Solutions, Ltd. | Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification |
AU2005307746B2 (en) | 2004-11-16 | 2011-05-12 | Illumina, Inc. | And methods and apparatus for reading coded microbeads |
US7830575B2 (en) | 2006-04-10 | 2010-11-09 | Illumina, Inc. | Optical scanner with improved scan time |
US7858924B2 (en) * | 2006-12-12 | 2010-12-28 | Abbott Laboratories, Inc. | Device for use in normalizing readings on a testing machine |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4351824A (en) * | 1981-02-05 | 1982-09-28 | Icl Scientific | Polystyrene latex reagents, methods of preparation, and use in immunological procedures |
JPS6036962A (ja) * | 1983-08-09 | 1985-02-26 | Toray Ind Inc | 生物学的検査用微粒子 |
US4774189A (en) * | 1984-12-24 | 1988-09-27 | Flow Cytometry Standards Corp. | Fluorescent calibration microbeads simulating stained cells |
EP0273115B1 (de) * | 1986-10-22 | 1994-09-07 | Abbott Laboratories | Chemilumineszierende Acridinium- und Phenantridiniumsalze |
US5132242A (en) * | 1987-07-15 | 1992-07-21 | Cheung Sau W | Fluorescent microspheres and methods of using them |
US5089424A (en) * | 1988-06-14 | 1992-02-18 | Abbott Laboratories | Method and apparatus for heterogeneous chemiluminescence assay |
-
1994
- 1994-02-15 US US08/196,536 patent/US5468649A/en not_active Expired - Lifetime
-
1995
- 1995-02-06 AT AT95909496T patent/ATE206523T1/de not_active IP Right Cessation
- 1995-02-06 ES ES95909496T patent/ES2165907T3/es not_active Expired - Lifetime
- 1995-02-06 AU AU17443/95A patent/AU1744395A/en not_active Abandoned
- 1995-02-06 CA CA002179310A patent/CA2179310A1/en not_active Abandoned
- 1995-02-06 EP EP95909496A patent/EP0745223B1/de not_active Expired - Lifetime
- 1995-02-06 JP JP52128495A patent/JP3580821B2/ja not_active Expired - Fee Related
- 1995-02-06 DE DE69523040T patent/DE69523040T2/de not_active Expired - Fee Related
- 1995-02-06 WO PCT/US1995/001527 patent/WO1995022059A1/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
US5468649A (en) | 1995-11-21 |
EP0745223A1 (de) | 1996-12-04 |
WO1995022059A1 (en) | 1995-08-17 |
CA2179310A1 (en) | 1995-08-17 |
JPH09509253A (ja) | 1997-09-16 |
JP3580821B2 (ja) | 2004-10-27 |
EP0745223B1 (de) | 2001-10-04 |
AU1744395A (en) | 1995-08-29 |
DE69523040T2 (de) | 2002-06-27 |
ATE206523T1 (de) | 2001-10-15 |
ES2165907T3 (es) | 2002-04-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |