US5656211A
(en)
*
|
1989-12-22 |
1997-08-12 |
Imarx Pharmaceutical Corp. |
Apparatus and method for making gas-filled vesicles of optimal size
|
US6088613A
(en)
|
1989-12-22 |
2000-07-11 |
Imarx Pharmaceutical Corp. |
Method of magnetic resonance focused surgical and therapeutic ultrasound
|
US5585112A
(en)
|
1989-12-22 |
1996-12-17 |
Imarx Pharmaceutical Corp. |
Method of preparing gas and gaseous precursor-filled microspheres
|
US5776429A
(en)
|
1989-12-22 |
1998-07-07 |
Imarx Pharmaceutical Corp. |
Method of preparing gas-filled microspheres using a lyophilized lipids
|
US5469854A
(en)
|
1989-12-22 |
1995-11-28 |
Imarx Pharmaceutical Corp. |
Methods of preparing gas-filled liposomes
|
US5305757A
(en)
|
1989-12-22 |
1994-04-26 |
Unger Evan C |
Gas filled liposomes and their use as ultrasonic contrast agents
|
US6001335A
(en)
|
1989-12-22 |
1999-12-14 |
Imarx Pharmaceutical Corp. |
Contrasting agents for ultrasonic imaging and methods for preparing the same
|
US20020150539A1
(en)
*
|
1989-12-22 |
2002-10-17 |
Unger Evan C. |
Ultrasound imaging and treatment
|
US5580575A
(en)
|
1989-12-22 |
1996-12-03 |
Imarx Pharmaceutical Corp. |
Therapeutic drug delivery systems
|
US6146657A
(en)
|
1989-12-22 |
2000-11-14 |
Imarx Pharmaceutical Corp. |
Gas-filled lipid spheres for use in diagnostic and therapeutic applications
|
US5705187A
(en)
|
1989-12-22 |
1998-01-06 |
Imarx Pharmaceutical Corp. |
Compositions of lipids and stabilizing materials
|
US5733572A
(en)
|
1989-12-22 |
1998-03-31 |
Imarx Pharmaceutical Corp. |
Gas and gaseous precursor filled microspheres as topical and subcutaneous delivery vehicles
|
US6551576B1
(en)
|
1989-12-22 |
2003-04-22 |
Bristol-Myers Squibb Medical Imaging, Inc. |
Container with multi-phase composition for use in diagnostic and therapeutic applications
|
US5542935A
(en)
|
1989-12-22 |
1996-08-06 |
Imarx Pharmaceutical Corp. |
Therapeutic delivery systems related applications
|
US5922304A
(en)
|
1989-12-22 |
1999-07-13 |
Imarx Pharmaceutical Corp. |
Gaseous precursor filled microspheres as magnetic resonance imaging contrast agents
|
US20010024638A1
(en)
*
|
1992-11-02 |
2001-09-27 |
Michel Schneider |
Stable microbubble suspensions as enhancement agents for ultrasound echography and dry formulations thereof
|
GB9106673D0
(en)
*
|
1991-03-28 |
1991-05-15 |
Hafslund Nycomed As |
Improvements in or relating to contrast agents
|
US5874062A
(en)
|
1991-04-05 |
1999-02-23 |
Imarx Pharmaceutical Corp. |
Methods of computed tomography using perfluorocarbon gaseous filled microspheres as contrast agents
|
US5205290A
(en)
|
1991-04-05 |
1993-04-27 |
Unger Evan C |
Low density microspheres and their use as contrast agents for computed tomography
|
MX9205298A
(es)
*
|
1991-09-17 |
1993-05-01 |
Steven Carl Quay |
Medios gaseosos de contraste de ultrasonido y metodo para seleccionar gases para usarse como medios de contraste de ultrasonido
|
IL108416A
(en)
|
1993-01-25 |
1998-10-30 |
Sonus Pharma Inc |
Colloids with phase difference as contrast ultrasound agents
|
US5798091A
(en)
|
1993-07-30 |
1998-08-25 |
Alliance Pharmaceutical Corp. |
Stabilized gas emulsion containing phospholipid for ultrasound contrast enhancement
|
DK0711179T3
(da)
|
1993-07-30 |
2005-02-14 |
Imcor Pharmaceutical Co |
Stabiliserede sammensætninger med mikrobobler til ultralyd
|
US7083572B2
(en)
*
|
1993-11-30 |
2006-08-01 |
Bristol-Myers Squibb Medical Imaging, Inc. |
Therapeutic delivery systems
|
US5736121A
(en)
|
1994-05-23 |
1998-04-07 |
Imarx Pharmaceutical Corp. |
Stabilized homogenous suspensions as computed tomography contrast agents
|
FR2721510B1
(fr)
*
|
1994-06-22 |
1996-07-26 |
Rhone Poulenc Rorer Sa |
Nanoparticules filtrables dans des conditions stériles.
|
US5876697A
(en)
*
|
1994-08-04 |
1999-03-02 |
Gakko Houjin Toin Gakuen |
Method for the production of microbubble-type ultrasonic contrast agent using fatty acid surfactants
|
CA2199864C
(en)
*
|
1994-09-16 |
2006-06-20 |
Seth A. Foerster |
Methods and devices for defining and marking tissue
|
US5540909A
(en)
*
|
1994-09-28 |
1996-07-30 |
Alliance Pharmaceutical Corp. |
Harmonic ultrasound imaging with microbubbles
|
US5767112A
(en)
*
|
1994-10-21 |
1998-06-16 |
Poli Industria Chimica, S.P.A. |
Muscle relaxant pharmaceutical compositions
|
US6743779B1
(en)
|
1994-11-29 |
2004-06-01 |
Imarx Pharmaceutical Corp. |
Methods for delivering compounds into a cell
|
US5830430A
(en)
|
1995-02-21 |
1998-11-03 |
Imarx Pharmaceutical Corp. |
Cationic lipids and the use thereof
|
US5997898A
(en)
|
1995-06-06 |
1999-12-07 |
Imarx Pharmaceutical Corp. |
Stabilized compositions of fluorinated amphiphiles for methods of therapeutic delivery
|
US6420549B1
(en)
|
1995-06-06 |
2002-07-16 |
Isis Pharmaceuticals, Inc. |
Oligonucleotide analogs having modified dimers
|
US5897851A
(en)
*
|
1995-06-07 |
1999-04-27 |
Sonus Pharmaceuticals, Inc. |
Nucleation and activation of a liquid-in-liquid emulsion for use in ultrasound imaging
|
US6521211B1
(en)
*
|
1995-06-07 |
2003-02-18 |
Bristol-Myers Squibb Medical Imaging, Inc. |
Methods of imaging and treatment with targeted compositions
|
US6231834B1
(en)
|
1995-06-07 |
2001-05-15 |
Imarx Pharmaceutical Corp. |
Methods for ultrasound imaging involving the use of a contrast agent and multiple images and processing of same
|
US5606973A
(en)
*
|
1995-06-07 |
1997-03-04 |
Molecular Biosystems, Inc. |
Liquid core microdroplets for ultrasound imaging
|
US5804162A
(en)
|
1995-06-07 |
1998-09-08 |
Alliance Pharmaceutical Corp. |
Gas emulsions stabilized with fluorinated ethers having low Ostwald coefficients
|
US6033645A
(en)
|
1996-06-19 |
2000-03-07 |
Unger; Evan C. |
Methods for diagnostic imaging by regulating the administration rate of a contrast agent
|
US6139819A
(en)
|
1995-06-07 |
2000-10-31 |
Imarx Pharmaceutical Corp. |
Targeted contrast agents for diagnostic and therapeutic use
|
US5855911A
(en)
*
|
1995-08-29 |
1999-01-05 |
Board Of Regents, The University Of Texas System |
Liposomal phosphodiester, phosphorothioate, and P-ethoxy oligonucleotides
|
ATE345682T1
(de)
|
1996-05-01 |
2006-12-15 |
Imarx Pharmaceutical Corp |
In vitro verfahren zum einbringen von nukleinsäuren in eine zelle
|
US7812149B2
(en)
|
1996-06-06 |
2010-10-12 |
Isis Pharmaceuticals, Inc. |
2′-Fluoro substituted oligomeric compounds and compositions for use in gene modulations
|
US5898031A
(en)
|
1996-06-06 |
1999-04-27 |
Isis Pharmaceuticals, Inc. |
Oligoribonucleotides for cleaving RNA
|
US9096636B2
(en)
|
1996-06-06 |
2015-08-04 |
Isis Pharmaceuticals, Inc. |
Chimeric oligomeric compounds and their use in gene modulation
|
US6414139B1
(en)
|
1996-09-03 |
2002-07-02 |
Imarx Therapeutics, Inc. |
Silicon amphiphilic compounds and the use thereof
|
US5846517A
(en)
|
1996-09-11 |
1998-12-08 |
Imarx Pharmaceutical Corp. |
Methods for diagnostic imaging using a renal contrast agent and a vasodilator
|
DE69737915T2
(de)
*
|
1996-09-11 |
2008-03-13 |
Bristol-Myers Squibb Medical Imaging, Inc. |
Verfahren zur diagnostischen Bilderzeugung der Nierenregion unter Verwendung eines Kontrastmittels und eines Vasodilators
|
WO1998013024A2
(en)
*
|
1996-09-27 |
1998-04-02 |
Hyal Pharmaceutical Corporation |
Hyaluronic drug delivery system
|
US6120751A
(en)
|
1997-03-21 |
2000-09-19 |
Imarx Pharmaceutical Corp. |
Charged lipids and uses for the same
|
US6143276A
(en)
|
1997-03-21 |
2000-11-07 |
Imarx Pharmaceutical Corp. |
Methods for delivering bioactive agents to regions of elevated temperatures
|
US6090800A
(en)
|
1997-05-06 |
2000-07-18 |
Imarx Pharmaceutical Corp. |
Lipid soluble steroid prodrugs
|
US5962015A
(en)
*
|
1997-05-02 |
1999-10-05 |
Kobo Products S.A.R.L. |
Stabilized liposomes
|
US20020039594A1
(en)
*
|
1997-05-13 |
2002-04-04 |
Evan C. Unger |
Solid porous matrices and methods of making and using the same
|
US6416740B1
(en)
|
1997-05-13 |
2002-07-09 |
Bristol-Myers Squibb Medical Imaging, Inc. |
Acoustically active drug delivery systems
|
GB9717589D0
(en)
*
|
1997-08-19 |
1997-10-22 |
Nycomed Imaging As |
Improvements in or relating to contrast agents
|
AU766783B2
(en)
*
|
1997-08-19 |
2003-10-23 |
Philipp Lang |
Ultrasonic transmission films and devices, particularly for hygienic transducer surfaces
|
US6548047B1
(en)
|
1997-09-15 |
2003-04-15 |
Bristol-Myers Squibb Medical Imaging, Inc. |
Thermal preactivation of gaseous precursor filled compositions
|
US6050943A
(en)
|
1997-10-14 |
2000-04-18 |
Guided Therapy Systems, Inc. |
Imaging, therapy, and temperature monitoring ultrasonic system
|
US6623430B1
(en)
|
1997-10-14 |
2003-09-23 |
Guided Therapy Systems, Inc. |
Method and apparatus for safety delivering medicants to a region of tissue using imaging, therapy and temperature monitoring ultrasonic system
|
US6270464B1
(en)
|
1998-06-22 |
2001-08-07 |
Artemis Medical, Inc. |
Biopsy localization method and device
|
US6123923A
(en)
|
1997-12-18 |
2000-09-26 |
Imarx Pharmaceutical Corp. |
Optoacoustic contrast agents and methods for their use
|
US6375980B1
(en)
*
|
1998-01-08 |
2002-04-23 |
Research Development Foundation |
Stabilization of lipid:DNA formulations during nebulization
|
US20010003580A1
(en)
|
1998-01-14 |
2001-06-14 |
Poh K. Hui |
Preparation of a lipid blend and a phospholipid suspension containing the lipid blend
|
US6395253B2
(en)
*
|
1998-04-23 |
2002-05-28 |
The Regents Of The University Of Michigan |
Microspheres containing condensed polyanionic bioactive agents and methods for their production
|
US7387772B1
(en)
|
1999-06-22 |
2008-06-17 |
Immunimedics, Inc. |
Chimeric, human and humanized anti-CSAP monoclonal antibodies
|
US6962702B2
(en)
*
|
1998-06-22 |
2005-11-08 |
Immunomedics Inc. |
Production and use of novel peptide-based agents for use with bi-specific antibodies
|
US7405320B2
(en)
|
1998-06-22 |
2008-07-29 |
Immunomedics, Inc. |
Therapeutic and diagnostic conjugates for use with multispecific antibodies
|
US7138103B2
(en)
*
|
1998-06-22 |
2006-11-21 |
Immunomedics, Inc. |
Use of bi-specific antibodies for pre-targeting diagnosis and therapy
|
US7833528B2
(en)
*
|
1998-06-22 |
2010-11-16 |
Immunomedics, Inc. |
Use of multispecific, non-covalent complexes for targeted delivery of therapeutics
|
US6077709A
(en)
|
1998-09-29 |
2000-06-20 |
Isis Pharmaceuticals Inc. |
Antisense modulation of Survivin expression
|
DE19906832C2
(de)
*
|
1999-02-18 |
2003-06-26 |
Dlw Ag |
Kontinuierliches Verfahren zur Herstellung eines vernetzten Bindemittels auf Basis ungesättigter Fettsäuren und/oder Fettsäureester, das Bindemittel sowie seine Verwendung
|
US7098192B2
(en)
|
1999-04-08 |
2006-08-29 |
Isis Pharmaceuticals, Inc. |
Antisense oligonucleotide modulation of STAT3 expression
|
US6572840B1
(en)
|
1999-07-28 |
2003-06-03 |
Bristol-Myers Squibb Pharma Company |
Stable microbubbles comprised of a perfluoropropane encapsulated lipid moiety for use as an ultrasound contrast agent
|
CA2385528C
(en)
|
1999-10-01 |
2013-12-10 |
Immunogen, Inc. |
Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
|
US6261840B1
(en)
|
2000-01-18 |
2001-07-17 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of PTP1B expression
|
US20020055479A1
(en)
|
2000-01-18 |
2002-05-09 |
Cowsert Lex M. |
Antisense modulation of PTP1B expression
|
DE60139112D1
(de)
*
|
2000-03-06 |
2009-08-13 |
Boston Scient Ltd |
Unter ultralschall sichtbare embolisierende substanzen
|
US6680172B1
(en)
|
2000-05-16 |
2004-01-20 |
Regents Of The University Of Michigan |
Treatments and markers for cancers of the central nervous system
|
EP2279757A3
(de)
|
2000-06-02 |
2011-08-03 |
Bracco Suisse SA |
Arzneimitteln zum Targeting von Endothelzellen
|
US7914453B2
(en)
|
2000-12-28 |
2011-03-29 |
Ardent Sound, Inc. |
Visual imaging system for ultrasonic probe
|
US20020185558A1
(en)
*
|
2001-06-12 |
2002-12-12 |
Lemanczyk Stephen M. |
Method of milling pharmaceutical preparation
|
US7803915B2
(en)
|
2001-06-20 |
2010-09-28 |
Genentech, Inc. |
Antibody compositions for the diagnosis and treatment of tumor
|
EP1992643A3
(de)
|
2001-06-20 |
2008-12-10 |
Genentech, Inc. |
Zusammensetzungen und Verfahren zur Behandlung und Diagnose von Tumoren
|
CA2790034A1
(en)
|
2001-06-21 |
2003-01-03 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of superoxide dismutase 1, soluble expression
|
JP3713561B2
(ja)
*
|
2001-06-26 |
2005-11-09 |
独立行政法人科学技術振興機構 |
有機液体による高配向整列カーボンナノチューブの合成方法及びその合成装置
|
US7425545B2
(en)
|
2001-07-25 |
2008-09-16 |
Isis Pharmaceuticals, Inc. |
Modulation of C-reactive protein expression
|
US6964950B2
(en)
|
2001-07-25 |
2005-11-15 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of C-reactive protein expression
|
US20030096772A1
(en)
|
2001-07-30 |
2003-05-22 |
Crooke Rosanne M. |
Antisense modulation of acyl CoA cholesterol acyltransferase-2 expression
|
US7407943B2
(en)
|
2001-08-01 |
2008-08-05 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of apolipoprotein B expression
|
US7227014B2
(en)
|
2001-08-07 |
2007-06-05 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of apolipoprotein (a) expression
|
US20030044354A1
(en)
*
|
2001-08-16 |
2003-03-06 |
Carpenter Alan P. |
Gas microsphere liposome composites for ultrasound imaging and ultrasound stimulated drug release
|
WO2003024392A2
(en)
|
2001-09-18 |
2003-03-27 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
US6750019B2
(en)
|
2001-10-09 |
2004-06-15 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of insulin-like growth factor binding protein 5 expression
|
NZ566396A
(en)
|
2001-10-09 |
2009-07-31 |
Isis Pharmaceuticals Inc |
Antisense modulation of insulin-like growth factor binding protein 5 expressions
|
WO2003088808A2
(en)
|
2002-04-16 |
2003-10-30 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
IL161733A0
(en)
|
2001-11-02 |
2005-11-20 |
Insert Therapeutics Inc |
Methods and compositions for therapeutic use of rna interference
|
US20030096774A1
(en)
*
|
2001-11-21 |
2003-05-22 |
Igor Gonda |
Compositions of nucleic acids and cationic aminoglycosides and methods of using and preparing the same
|
US6965025B2
(en)
|
2001-12-10 |
2005-11-15 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of connective tissue growth factor expression
|
US20030147812A1
(en)
*
|
2001-12-11 |
2003-08-07 |
Friedrich Ueberle |
Device and methods for initiating chemical reactions and for the targeted delivery of drugs or other agents
|
EP1575571A4
(de)
|
2002-01-02 |
2008-06-25 |
Genentech Inc |
Zusammensetzungen und verfahren zur diagnose und behandlung eines tumors
|
US7211240B2
(en)
|
2002-03-01 |
2007-05-01 |
Bracco International B.V. |
Multivalent constructs for therapeutic and diagnostic applications
|
EP1587944A4
(de)
|
2002-03-01 |
2007-03-21 |
Dyax Corp |
Kdr und vegf/kdr-bindende peptide und ihre diagnostische und therapeutische veranwendung bei der diagnose und therapie
|
US7794693B2
(en)
|
2002-03-01 |
2010-09-14 |
Bracco International B.V. |
Targeting vector-phospholipid conjugates
|
US7261876B2
(en)
|
2002-03-01 |
2007-08-28 |
Bracco International Bv |
Multivalent constructs for therapeutic and diagnostic applications
|
JP2006514915A
(ja)
|
2002-03-01 |
2006-05-18 |
ダイアックス、コープ |
Kdrおよびvegf/kdr結合ペプチドならびに診断および治療におけるその使用
|
US7666979B2
(en)
|
2002-03-01 |
2010-02-23 |
Bracco International B.V. |
Methods for preparing multivalent constructs for therapeutic and diagnostic applications and methods of preparing the same
|
US8623822B2
(en)
|
2002-03-01 |
2014-01-07 |
Bracco Suisse Sa |
KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy
|
US7985402B2
(en)
|
2002-03-01 |
2011-07-26 |
Bracco Suisse Sa |
Targeting vector-phospholipid conjugates
|
US20030180712A1
(en)
|
2002-03-20 |
2003-09-25 |
Biostratum Ab |
Inhibition of the beta3 subunit of L-type Ca2+ channels
|
US7131997B2
(en)
*
|
2002-03-29 |
2006-11-07 |
Scimed Life Systems, Inc. |
Tissue treatment
|
US7462366B2
(en)
*
|
2002-03-29 |
2008-12-09 |
Boston Scientific Scimed, Inc. |
Drug delivery particle
|
US7094369B2
(en)
*
|
2002-03-29 |
2006-08-22 |
Scimed Life Systems, Inc. |
Processes for manufacturing polymeric microspheres
|
AU2003223451A1
(en)
*
|
2002-04-03 |
2003-10-20 |
Jackie R. See |
Methods for ultrasonic imaging and treating diseased tissues
|
DE10214983A1
(de)
*
|
2002-04-04 |
2004-04-08 |
TransMIT Gesellschaft für Technologietransfer mbH |
Vernebelbare Liposomen und ihre Verwendung zur pulmonalen Applikation von Wirkstoffen
|
US7053134B2
(en)
*
|
2002-04-04 |
2006-05-30 |
Scimed Life Systems, Inc. |
Forming a chemically cross-linked particle of a desired shape and diameter
|
US7199107B2
(en)
|
2002-05-23 |
2007-04-03 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of kinesin-like 1 expression
|
US20040076582A1
(en)
*
|
2002-08-30 |
2004-04-22 |
Dimatteo Kristian |
Agent delivery particle
|
US7449236B2
(en)
*
|
2002-08-09 |
2008-11-11 |
Boston Scientific Scimed, Inc. |
Porous polymeric particle comprising polyvinyl alcohol and having interior to surface porosity-gradient
|
US7842377B2
(en)
*
|
2003-08-08 |
2010-11-30 |
Boston Scientific Scimed, Inc. |
Porous polymeric particle comprising polyvinyl alcohol and having interior to surface porosity-gradient
|
US8012454B2
(en)
|
2002-08-30 |
2011-09-06 |
Boston Scientific Scimed, Inc. |
Embolization
|
EP1537208A1
(de)
|
2002-09-13 |
2005-06-08 |
Replicor, Inc. |
Nicht-sequenzkomplementäre antivirale oligonukleotide
|
WO2004031350A2
(en)
|
2002-09-26 |
2004-04-15 |
Amgen, Inc. |
Modulation of forkhead box o1a expression
|
US7588825B2
(en)
*
|
2002-10-23 |
2009-09-15 |
Boston Scientific Scimed, Inc. |
Embolic compositions
|
US7883490B2
(en)
|
2002-10-23 |
2011-02-08 |
Boston Scientific Scimed, Inc. |
Mixing and delivery of therapeutic compositions
|
US20040093056A1
(en)
|
2002-10-26 |
2004-05-13 |
Johnson Lianw M. |
Medical appliance delivery apparatus and method of use
|
CA2504720C
(en)
|
2002-11-05 |
2013-12-24 |
Isis Pharmaceuticals, Inc. |
Chimeric oligomeric compounds and their use in gene modulation
|
WO2004044139A2
(en)
|
2002-11-05 |
2004-05-27 |
Isis Parmaceuticals, Inc. |
Modified oligonucleotides for use in rna interference
|
CA2505801A1
(en)
|
2002-11-13 |
2004-05-27 |
Rosanne Crooke |
Antisense modulation of apolipoprotein b expression
|
DK1569695T3
(da)
|
2002-11-13 |
2013-08-05 |
Genzyme Corp |
Antisense-modulering af apolipoprotein-b-ekspression
|
US7144999B2
(en)
|
2002-11-23 |
2006-12-05 |
Isis Pharmaceuticals, Inc. |
Modulation of hypoxia-inducible factor 1 alpha expression
|
NZ541637A
(en)
|
2003-02-11 |
2008-07-31 |
Antisense Therapeutics Pty Ltd |
Modulation of insulin like growth factor I receptor
|
US7803781B2
(en)
|
2003-02-28 |
2010-09-28 |
Isis Pharmaceuticals, Inc. |
Modulation of growth hormone receptor expression and insulin-like growth factor expression
|
SI2949658T1
(sl)
|
2003-03-03 |
2018-10-30 |
Dyax Corp. |
Peptidi, ki specifično vežejo HGF receptor (cMet) in njihove uporabe
|
US20040185559A1
(en)
|
2003-03-21 |
2004-09-23 |
Isis Pharmaceuticals Inc. |
Modulation of diacylglycerol acyltransferase 1 expression
|
US7637934B2
(en)
*
|
2003-03-31 |
2009-12-29 |
Merit Medical Systems, Inc. |
Medical appliance optical delivery and deployment apparatus and method
|
US7598227B2
(en)
|
2003-04-16 |
2009-10-06 |
Isis Pharmaceuticals Inc. |
Modulation of apolipoprotein C-III expression
|
AU2004231740A1
(en)
*
|
2003-04-17 |
2004-11-04 |
The Trustees Of Columbia University In The City Ofnew York |
Desmoglein 4 is a novel gene involved in hair growth
|
US7399853B2
(en)
|
2003-04-28 |
2008-07-15 |
Isis Pharmaceuticals |
Modulation of glucagon receptor expression
|
CN1984921B
(zh)
|
2003-06-03 |
2010-06-16 |
Isis药物公司 |
存活蛋白表达的调节
|
CA2533701A1
(en)
|
2003-07-31 |
2005-02-17 |
Isis Pharmaceuticals, Inc. |
Oligomeric compounds and compositions for use in modulation of small non-coding rnas
|
US7825235B2
(en)
|
2003-08-18 |
2010-11-02 |
Isis Pharmaceuticals, Inc. |
Modulation of diacylglycerol acyltransferase 2 expression
|
US7358226B2
(en)
*
|
2003-08-27 |
2008-04-15 |
The Regents Of The University Of California |
Ultrasonic concentration of drug delivery capsules
|
US7976823B2
(en)
|
2003-08-29 |
2011-07-12 |
Boston Scientific Scimed, Inc. |
Ferromagnetic particles and methods
|
EP1673108A4
(de)
*
|
2003-09-09 |
2009-06-03 |
Point Biomedical Corp |
Verfahren und zusammensetzungen für die ultraschalldarstellung von apoptose
|
US7906125B2
(en)
*
|
2003-09-18 |
2011-03-15 |
Boston Scientific Scimed, Inc. |
Solid or semi-solid therapeutic formulations
|
EP1668130A2
(de)
|
2003-09-18 |
2006-06-14 |
Isis Pharmaceuticals, Inc. |
Modulation der eif4e-expression
|
ES2437491T3
(es)
|
2003-10-10 |
2014-01-10 |
Alchemia Oncology Pty Limited |
Modulación de la síntesis y degradación de hialuronano en el tratamiento de enfermedad
|
US20050191653A1
(en)
|
2003-11-03 |
2005-09-01 |
Freier Susan M. |
Modulation of SGLT2 expression
|
US7901770B2
(en)
|
2003-11-04 |
2011-03-08 |
Boston Scientific Scimed, Inc. |
Embolic compositions
|
EP1689432B1
(de)
|
2003-11-17 |
2009-12-30 |
Genentech, Inc. |
Zusammensetzungen und verfahren zur behandlung von tumoren hämatopoetischen ursprungs
|
EP2363480A3
(de)
|
2004-01-20 |
2015-10-07 |
Isis Pharmaceuticals, Inc. |
Modulierung der Glukokortikoid-Rezeptor-Expression
|
US7468431B2
(en)
|
2004-01-22 |
2008-12-23 |
Isis Pharmaceuticals, Inc. |
Modulation of eIF4E-BP2 expression
|
US7736671B2
(en)
|
2004-03-02 |
2010-06-15 |
Boston Scientific Scimed, Inc. |
Embolization
|
US8569474B2
(en)
|
2004-03-09 |
2013-10-29 |
Isis Pharmaceuticals, Inc. |
Double stranded constructs comprising one or more short strands hybridized to a longer strand
|
WO2005089268A2
(en)
|
2004-03-15 |
2005-09-29 |
Isis Pharmaceuticals, Inc. |
Compositions and methods for optimizing cleavage of rna by rnase h
|
US7770455B2
(en)
*
|
2004-03-16 |
2010-08-10 |
Tribo Flow Separations, Llc |
Instruments, related systems, and methods for monitoring or controlling foaming
|
JP5184077B2
(ja)
*
|
2004-03-26 |
2013-04-17 |
キュリス,インコーポレイテッド |
ヘッジホッグシグナリングのrna干渉モジュレーター及びその利用
|
US8173176B2
(en)
|
2004-03-30 |
2012-05-08 |
Boston Scientific Scimed, Inc. |
Embolization
|
US20050244869A1
(en)
|
2004-04-05 |
2005-11-03 |
Brown-Driver Vickie L |
Modulation of transthyretin expression
|
US20050238870A1
(en)
*
|
2004-04-22 |
2005-10-27 |
Marcia Buiser |
Embolization
|
US7311861B2
(en)
|
2004-06-01 |
2007-12-25 |
Boston Scientific Scimed, Inc. |
Embolization
|
US8394947B2
(en)
|
2004-06-03 |
2013-03-12 |
Isis Pharmaceuticals, Inc. |
Positionally modified siRNA constructs
|
US8012457B2
(en)
|
2004-06-04 |
2011-09-06 |
Acusphere, Inc. |
Ultrasound contrast agent dosage formulation
|
US7884086B2
(en)
|
2004-09-08 |
2011-02-08 |
Isis Pharmaceuticals, Inc. |
Conjugates for use in hepatocyte free uptake assays
|
US9011336B2
(en)
|
2004-09-16 |
2015-04-21 |
Guided Therapy Systems, Llc |
Method and system for combined energy therapy profile
|
US7393325B2
(en)
|
2004-09-16 |
2008-07-01 |
Guided Therapy Systems, L.L.C. |
Method and system for ultrasound treatment with a multi-directional transducer
|
US7824348B2
(en)
|
2004-09-16 |
2010-11-02 |
Guided Therapy Systems, L.L.C. |
System and method for variable depth ultrasound treatment
|
US8535228B2
(en)
|
2004-10-06 |
2013-09-17 |
Guided Therapy Systems, Llc |
Method and system for noninvasive face lifts and deep tissue tightening
|
US10864385B2
(en)
|
2004-09-24 |
2020-12-15 |
Guided Therapy Systems, Llc |
Rejuvenating skin by heating tissue for cosmetic treatment of the face and body
|
US8444562B2
(en)
|
2004-10-06 |
2013-05-21 |
Guided Therapy Systems, Llc |
System and method for treating muscle, tendon, ligament and cartilage tissue
|
US20120165668A1
(en)
|
2010-08-02 |
2012-06-28 |
Guided Therapy Systems, Llc |
Systems and methods for treating acute and/or chronic injuries in soft tissue
|
JP5101288B2
(ja)
|
2004-10-05 |
2012-12-19 |
カリフォルニア インスティテュート オブ テクノロジー |
アプタマー調節される核酸及びその利用
|
US11883688B2
(en)
|
2004-10-06 |
2024-01-30 |
Guided Therapy Systems, Llc |
Energy based fat reduction
|
US8663112B2
(en)
|
2004-10-06 |
2014-03-04 |
Guided Therapy Systems, Llc |
Methods and systems for fat reduction and/or cellulite treatment
|
US7758524B2
(en)
|
2004-10-06 |
2010-07-20 |
Guided Therapy Systems, L.L.C. |
Method and system for ultra-high frequency ultrasound treatment
|
KR20130080477A
(ko)
|
2004-10-06 |
2013-07-12 |
가이디드 테라피 시스템스, 엘.엘.씨. |
초음파 치료 시스템
|
US9827449B2
(en)
|
2004-10-06 |
2017-11-28 |
Guided Therapy Systems, L.L.C. |
Systems for treating skin laxity
|
KR101328103B1
(ko)
|
2004-10-06 |
2013-11-13 |
가이디드 테라피 시스템스, 엘.엘.씨. |
비침습적 미용 증진 방법 및 시스템
|
US11235179B2
(en)
|
2004-10-06 |
2022-02-01 |
Guided Therapy Systems, Llc |
Energy based skin gland treatment
|
US8690779B2
(en)
|
2004-10-06 |
2014-04-08 |
Guided Therapy Systems, Llc |
Noninvasive aesthetic treatment for tightening tissue
|
US9694212B2
(en)
|
2004-10-06 |
2017-07-04 |
Guided Therapy Systems, Llc |
Method and system for ultrasound treatment of skin
|
US8133180B2
(en)
|
2004-10-06 |
2012-03-13 |
Guided Therapy Systems, L.L.C. |
Method and system for treating cellulite
|
US20060111744A1
(en)
|
2004-10-13 |
2006-05-25 |
Guided Therapy Systems, L.L.C. |
Method and system for treatment of sweat glands
|
US11724133B2
(en)
|
2004-10-07 |
2023-08-15 |
Guided Therapy Systems, Llc |
Ultrasound probe for treatment of skin
|
US11207548B2
(en)
|
2004-10-07 |
2021-12-28 |
Guided Therapy Systems, L.L.C. |
Ultrasound probe for treating skin laxity
|
US8425550B2
(en)
|
2004-12-01 |
2013-04-23 |
Boston Scientific Scimed, Inc. |
Embolic coils
|
CA2596506C
(en)
|
2005-02-09 |
2021-04-06 |
Avi Biopharma, Inc. |
Antisense composition and method for treating muscle atrophy
|
WO2006086771A2
(en)
*
|
2005-02-11 |
2006-08-17 |
Whatman, Inc. |
Devices and methods for handling and processing punches
|
US7858183B2
(en)
|
2005-03-02 |
2010-12-28 |
Boston Scientific Scimed, Inc. |
Particles
|
US7727555B2
(en)
|
2005-03-02 |
2010-06-01 |
Boston Scientific Scimed, Inc. |
Particles
|
CN101175769A
(zh)
|
2005-03-10 |
2008-05-07 |
健泰科生物技术公司 |
用于调控血管完整性的方法和组合物
|
ES2381201T3
(es)
|
2005-03-31 |
2012-05-24 |
Calando Pharmaceuticals, Inc. |
Inhibidores de la subunidad 2 de la ribonucleótido-reductasa y utilizaciones de los mismos
|
JP4695188B2
(ja)
|
2005-04-25 |
2011-06-08 |
アーデント サウンド, インコーポレイテッド |
コンピュータ周辺機器の安全性を向上させるための方法および装置
|
US7963287B2
(en)
|
2005-04-28 |
2011-06-21 |
Boston Scientific Scimed, Inc. |
Tissue-treatment methods
|
US20070004973A1
(en)
*
|
2005-06-15 |
2007-01-04 |
Tan Sharon M L |
Tissue treatment methods
|
US9463426B2
(en)
|
2005-06-24 |
2016-10-11 |
Boston Scientific Scimed, Inc. |
Methods and systems for coating particles
|
US20070083219A1
(en)
*
|
2005-10-12 |
2007-04-12 |
Buiser Marcia S |
Embolic coil introducer sheath locking mechanisms
|
US8007509B2
(en)
|
2005-10-12 |
2011-08-30 |
Boston Scientific Scimed, Inc. |
Coil assemblies, components and methods
|
US8257338B2
(en)
*
|
2006-10-27 |
2012-09-04 |
Artenga, Inc. |
Medical microbubble generation
|
WO2007062380A2
(en)
|
2005-11-21 |
2007-05-31 |
Isis Pharmaceuticals, Inc. |
Modulation of eif4e-bp2 expression
|
US8101197B2
(en)
|
2005-12-19 |
2012-01-24 |
Stryker Corporation |
Forming coils
|
US20070142859A1
(en)
*
|
2005-12-19 |
2007-06-21 |
Boston Scientific Scimed, Inc. |
Embolic coils
|
US8152839B2
(en)
|
2005-12-19 |
2012-04-10 |
Boston Scientific Scimed, Inc. |
Embolic coils
|
US7947368B2
(en)
|
2005-12-21 |
2011-05-24 |
Boston Scientific Scimed, Inc. |
Block copolymer particles
|
US20070142560A1
(en)
*
|
2005-12-21 |
2007-06-21 |
Young-Ho Song |
Block copolymer particles
|
US7501179B2
(en)
*
|
2005-12-21 |
2009-03-10 |
Boston Scientific Scimed, Inc. |
Block copolymer particles
|
EP3210633B1
(de)
|
2006-01-26 |
2019-06-19 |
Ionis Pharmaceuticals, Inc. |
Zusammensetzungen und deren verwendungen in bezug auf huntingtin
|
EP2614839A3
(de)
|
2006-04-05 |
2015-01-28 |
Genentech, Inc. |
Verfahren zur Verwendung von BOC/CDO zur Modulation der Hedgehog-Signalisierung
|
WO2007125173A2
(en)
|
2006-05-03 |
2007-11-08 |
Baltic Technology Development, Ltd. |
Antisense agents combining strongly bound base - modified oligonucleotide and artificial nuclease
|
US20070299461A1
(en)
*
|
2006-06-21 |
2007-12-27 |
Boston Scientific Scimed, Inc. |
Embolic coils and related components, systems, and methods
|
WO2008011473A2
(en)
|
2006-07-19 |
2008-01-24 |
Isis Pharmaceuticals, Inc. |
Compositions and their uses directed to hbxip
|
US9566454B2
(en)
|
2006-09-18 |
2017-02-14 |
Guided Therapy Systems, Llc |
Method and sysem for non-ablative acne treatment and prevention
|
US8414927B2
(en)
|
2006-11-03 |
2013-04-09 |
Boston Scientific Scimed, Inc. |
Cross-linked polymer particles
|
US8158595B2
(en)
|
2006-11-09 |
2012-04-17 |
California Institute Of Technology |
Modular aptamer-regulated ribozymes
|
US20080145658A1
(en)
*
|
2006-12-15 |
2008-06-19 |
Boston Scientific Scimed, Inc. |
Freeze Thaw Methods For Making Polymer Particles
|
EP2118118B1
(de)
*
|
2007-01-19 |
2017-09-27 |
Exiqon A/S |
Vermittelte zelluläre verabreichung von lna-oligonukleotiden
|
WO2008094945A2
(en)
|
2007-01-29 |
2008-08-07 |
Isis Pharmaceuticals, Inc. |
Compounds and methods for modulating protein expression
|
WO2009045469A2
(en)
|
2007-10-02 |
2009-04-09 |
Amgen Inc. |
Increasing erythropoietin using nucleic acids hybridizable to micro-rna and precursors thereof
|
US7875431B2
(en)
|
2007-02-22 |
2011-01-25 |
Genentech, Inc. |
Methods for detecting inflammatory bowel disease
|
US8178483B2
(en)
*
|
2007-03-30 |
2012-05-15 |
Colgate-Palmolive Company |
Polymeric encapsulates having a quaternary ammonium salt and methods for producing the same
|
TWI526233B
(zh)
|
2007-05-07 |
2016-03-21 |
指導治療系統股份有限公司 |
利用聲波能量調製藥劑輸送及效能之系統
|
US20150174388A1
(en)
|
2007-05-07 |
2015-06-25 |
Guided Therapy Systems, Llc |
Methods and Systems for Ultrasound Assisted Delivery of a Medicant to Tissue
|
WO2009011855A2
(en)
*
|
2007-07-16 |
2009-01-22 |
California Institute Of Technology |
Selection of nucleic acid-based sensor domains within nucleic acid switch platform
|
US8367815B2
(en)
*
|
2007-08-28 |
2013-02-05 |
California Institute Of Technology |
Modular polynucleotides for ligand-controlled regulatory systems
|
US20120165387A1
(en)
|
2007-08-28 |
2012-06-28 |
Smolke Christina D |
General composition framework for ligand-controlled RNA regulatory systems
|
US20090069870A1
(en)
*
|
2007-09-07 |
2009-03-12 |
Steven Haase |
Ionic foot bath array
|
US8865667B2
(en)
*
|
2007-09-12 |
2014-10-21 |
California Institute Of Technology |
Higher-order cellular information processing devices
|
EP2200652B1
(de)
*
|
2007-09-27 |
2018-03-21 |
Children's Medical Center Corporation |
Mikrobläschen und sauerstoffabgabe-verfahren
|
US9029524B2
(en)
*
|
2007-12-10 |
2015-05-12 |
California Institute Of Technology |
Signal activated RNA interference
|
WO2009083972A2
(en)
*
|
2008-01-03 |
2009-07-09 |
Do-Coop Technologies Ltd. |
Compositions and methods for enhancing the activity of podophyllotoxin
|
US8114983B2
(en)
|
2008-04-04 |
2012-02-14 |
Calando Pharmaceuticals, Inc. |
Compositions and use of EPAS1 inhibitors
|
CA3206234A1
(en)
|
2008-06-06 |
2009-12-10 |
Ulthera, Inc. |
A system and method for cosmetic treatment and imaging
|
WO2010008582A2
(en)
|
2008-07-18 |
2010-01-21 |
Rxi Pharmaceuticals Corporation |
Phagocytic cell drug delivery system
|
US20120034157A1
(en)
*
|
2010-08-03 |
2012-02-09 |
Searete Llc, A Limited Liability Corporation Of The State Of Delaware |
Artificial cells
|
EP3081648A1
(de)
|
2008-08-25 |
2016-10-19 |
Excaliard Pharmaceuticals, Inc. |
Gegen den bindegewebe-wachstumsfaktor gerichtete antisense-oligonukleotide und verwendungen davon
|
US10138485B2
(en)
|
2008-09-22 |
2018-11-27 |
Rxi Pharmaceuticals Corporation |
Neutral nanotransporters
|
GB0821180D0
(en)
*
|
2008-11-20 |
2008-12-24 |
Surgicaledge Systems Ltd |
Apparatus and method of fluid delivery
|
ES2629630T3
(es)
|
2008-12-04 |
2017-08-11 |
Curna, Inc. |
Tratamiento de enfermedades relacionadas con eritropoyetina (EPO) mediante inhibición del transcrito antisentido natural a EPO
|
US20110294870A1
(en)
|
2008-12-04 |
2011-12-01 |
Opko Curna, Llc |
Treatment of tumor suppressor gene related diseases by inhibition of natural antisense transcript to the gene
|
CN102307997B
(zh)
|
2008-12-04 |
2018-03-30 |
库尔纳公司 |
通过抑制针对沉默调节蛋白1的天然反义转录物来治疗沉默调节蛋白1(sirt1)相关的疾病
|
WO2010078536A1
(en)
|
2009-01-05 |
2010-07-08 |
Rxi Pharmaceuticals Corporation |
Inhibition of pcsk9 through rnai
|
CN102439149B
(zh)
|
2009-02-12 |
2018-01-02 |
库尔纳公司 |
通过抑制针对胶质细胞衍生神经营养因子(gdnf)的天然反义转录物来治疗gdnf相关的疾病
|
ES2762610T3
(es)
|
2009-02-12 |
2020-05-25 |
Curna Inc |
Tratamiento de enfermedades relacionadas con el factor neurotrófico derivado de cerebro (BDNF) por inhibición de transcrito antisentido natural para BDNF
|
US8329882B2
(en)
|
2009-02-18 |
2012-12-11 |
California Institute Of Technology |
Genetic control of mammalian cells with synthetic RNA regulatory systems
|
ES2845644T3
(es)
|
2009-03-04 |
2021-07-27 |
Curna Inc |
Tratamiento de enfermedades relacionadas con sirtuina1 (SIRT1) mediante inhibición del transcrito del antisentido natural a sirtuina 1
|
MX2011009751A
(es)
|
2009-03-16 |
2011-09-29 |
Opko Curna Llc |
Tratamiento de enfermedades relacionadas con factor nuclear (eritroide derivado 2) tipo 2 (nrf2) por inhibicion del transcrito antisentido natural a nrf2.
|
WO2010107740A2
(en)
|
2009-03-17 |
2010-09-23 |
Curna, Inc. |
Treatment of delta-like 1 homolog (dlk1) related diseases by inhibition of natural antisense transcript to dlk1
|
US9145555B2
(en)
|
2009-04-02 |
2015-09-29 |
California Institute Of Technology |
Integrated—ligand-responsive microRNAs
|
EP3524275A1
(de)
|
2009-04-22 |
2019-08-14 |
Massachusetts Institute Of Technology |
Angeborene immununterdrückung ermöglicht die wiederholte verabreichung von langen rna-molekülen
|
EP2424987B1
(de)
|
2009-05-01 |
2017-11-15 |
CuRNA, Inc. |
Behandlung von hämoglobin (hbf / hbg) verwandten krankheiten durch die inhibition des natürlichen antisense transcripts zu hbf / hbg
|
CN102459596B
(zh)
|
2009-05-06 |
2016-09-07 |
库尔纳公司 |
通过针对脂质转运和代谢基因的天然反义转录物的抑制治疗脂质转运和代谢基因相关疾病
|
JP6250930B2
(ja)
|
2009-05-06 |
2017-12-20 |
クルナ・インコーポレーテッド |
トリステトラプロリン(ttp)に対する天然アンチセンス転写物の抑制によるttp関連疾患の治療
|
CN102575251B
(zh)
|
2009-05-18 |
2018-12-04 |
库尔纳公司 |
通过抑制针对重编程因子的天然反义转录物来治疗重编程因子相关的疾病
|
KR101703695B1
(ko)
|
2009-05-22 |
2017-02-08 |
큐알엔에이, 인크. |
전사 인자 e3(tfe3)에 대한 천연 안티센스 전사체의 억제에 의해 tfe3 및 인슐린 수용체 기질 2(irs2)의 치료
|
CN103221541B
(zh)
|
2009-05-28 |
2017-03-01 |
库尔纳公司 |
通过抑制抗病毒基因的天然反义转录物来治疗抗病毒基因相关疾病
|
WO2010148050A2
(en)
|
2009-06-16 |
2010-12-23 |
Curna, Inc. |
Treatment of collagen gene related diseases by inhibition of natural antisense transcript to a collagen gene
|
KR101702689B1
(ko)
|
2009-06-16 |
2017-02-06 |
큐알엔에이, 인크. |
Pon1에 대한 천연 안티센스 전사체의 억제에 의한 파라옥소나제 1(pon1) 관련된 질환의 치료
|
CA2765889A1
(en)
|
2009-06-24 |
2010-12-29 |
Opko Curna, Llc |
Treatment of tumor necrosis factor receptor 2 (tnfr2) related diseases by inhibition of natural antisense transcript to tnfr2
|
CA2765815A1
(en)
|
2009-06-26 |
2010-12-29 |
Opko Curna, Llc |
Treatment of down syndrome gene related diseases by inhibition of natural antisense transcript to a down syndrome gene
|
DE102009031274A1
(de)
|
2009-06-30 |
2011-01-13 |
Justus-Liebig-Universität Giessen |
Liposomen zur pulmonalen Applikation
|
US9234199B2
(en)
|
2009-08-05 |
2016-01-12 |
Curna, Inc. |
Treatment of insulin gene (INS) related diseases by inhibition of natural antisense transcript to an insulin gene (INS)
|
CN102482671B
(zh)
|
2009-08-25 |
2017-12-01 |
库尔纳公司 |
通过抑制‘含有iq模体的gtp酶激活蛋白’(iqgap)的天然反义转录物而治疗iqgap相关疾病
|
JP5771366B2
(ja)
*
|
2009-09-02 |
2015-08-26 |
株式会社バイオメッドコア |
リポソーム製造装置及び方法
|
US9321823B2
(en)
|
2009-09-02 |
2016-04-26 |
Genentech, Inc. |
Mutant smoothened and methods of using the same
|
WO2011029094A2
(en)
|
2009-09-04 |
2011-03-10 |
The University Of North Carolina At Chapel Hill |
Systems, methods, and computer readable media for high- frequency contrast imaging and image-guided therapeutics
|
CA2780741C
(en)
|
2009-10-12 |
2023-04-04 |
Smith Holdings, Llc |
Methods and compositions for modulating gene expression using oligonucleotide based drugs administered in vivo or in vitro
|
NL2003660C2
(en)
*
|
2009-10-16 |
2011-04-19 |
Giskit B V |
Composition and method for medical imaging of body cavities.
|
BR112012009409A2
(pt)
|
2009-10-22 |
2017-02-21 |
Genentech Inc |
método de identificação de uma substância inibidora, molécula antagonista, ácido nucleico isolado, vetor, célula hospedeira, método para fabricar a molécula, composição, artigo de fabricação, método de inibição de uma atividade biológica, método de tratamento de uma condição patológica, método para detectar msp em uma amostra e método para detectar hepsina em uma amostra
|
US20120244169A1
(en)
|
2009-11-06 |
2012-09-27 |
Fibrogen, Inc. |
Treatment for Radiation-Induced Disorders
|
US8715186B2
(en)
|
2009-11-24 |
2014-05-06 |
Guided Therapy Systems, Llc |
Methods and systems for generating thermal bubbles for improved ultrasound imaging and therapy
|
AR079217A1
(es)
|
2009-11-30 |
2012-01-04 |
Genentech Inc |
Composiciones y metodos para el diagnostico y el tratamiento de tumores
|
MX2012006580A
(es)
|
2009-12-11 |
2012-09-28 |
Genecode As |
Metodo para facilitar la sobrevivencia de celulas neurales usando mimeticos de ligandos (gfl) de la familia gdnf o activadores de la ruta de señalizacion de ret.
|
ES2661813T3
(es)
|
2009-12-16 |
2018-04-04 |
Curna, Inc. |
Tratamiento de enfermedades relacionadas con la peptidasa del factor de transcripción de membrana, sitio 1 (mbtps1) mediante inhibición del transcrito antisentido natural al gen mbtps1
|
US9068183B2
(en)
|
2009-12-23 |
2015-06-30 |
Curna, Inc. |
Treatment of uncoupling protein 2 (UCP2) related diseases by inhibition of natural antisense transcript to UCP2
|
CA2782373C
(en)
|
2009-12-23 |
2019-03-26 |
Opko Curna, Llc |
Treatment of hepatocyte growth factor (hgf) related diseases by inhibition of natural antisense transcript to hgf
|
WO2011090740A2
(en)
|
2009-12-29 |
2011-07-28 |
Opko Curna, Llc |
Treatment of nuclear respiratory factor 1 (nrf1) related diseases by inhibition of natural antisense transcript to nrf1
|
ES2585829T3
(es)
|
2009-12-29 |
2016-10-10 |
Curna, Inc. |
Tratamiento de las enfermedades relacionadas con la proteína tumoral 63 (p63) por inhibición de transcripción antisentido natural a p63
|
KR101878501B1
(ko)
|
2010-01-04 |
2018-08-07 |
큐알엔에이, 인크. |
인터페론 조절 인자 8 (irf8)에 대한 자연 안티센스 전사체의 저해에 의한 인터페론 조절 인자 8 (irf8) 관련된 질환의 치료
|
EP2521785B1
(de)
|
2010-01-06 |
2022-03-09 |
CuRNA, Inc. |
Inhibition des natürlichen antisense-transkripts des pankreasentwicklungsgens zur verwendung in der behandlung von pankreatischen entwicklungsgenbezogenen krankheiten
|
DK2524039T3
(en)
|
2010-01-11 |
2018-03-12 |
Curna Inc |
TREATMENT OF GENDER HORMON-BINDING GLOBULIN (SHBG) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENCE TRANSCRIPTS TO SHBG
|
US8883739B2
(en)
|
2010-01-19 |
2014-11-11 |
The Trustees Of Columbia University In The City Of New York |
Osteocalcin as a treatment for male reproductive disorders
|
CN102782135A
(zh)
|
2010-01-25 |
2012-11-14 |
库尔纳公司 |
通过抑制rna酶h1的天然反义转录物而治疗rna酶h1相关疾病
|
CN102844435B
(zh)
|
2010-02-22 |
2017-05-10 |
库尔纳公司 |
通过抑制吡咯啉‑5‑羧酸还原酶1(pycr1)的天然反义转录物而治疗pycr1相关疾病
|
MX2012009215A
(es)
|
2010-02-23 |
2012-11-23 |
Genentech Inc |
Composiciones y metodos para el diagnostico y tratamiento de tumores.
|
RU2610661C2
(ru)
|
2010-04-09 |
2017-02-14 |
Курна, Инк. |
Лечение заболеваний, связанных с фактором роста фибробластов 21 (fgf21), путем ингибирования природного антисмыслового транскрипта к fgf21
|
JP5735488B2
(ja)
*
|
2010-04-09 |
2015-06-17 |
株式会社日立製作所 |
超音波診断治療装置
|
WO2011139917A1
(en)
|
2010-04-29 |
2011-11-10 |
Isis Pharmaceuticals, Inc. |
Modulation of transthyretin expression
|
CN107988228B
(zh)
|
2010-05-03 |
2022-01-25 |
库尔纳公司 |
通过抑制沉默调节蛋白(sirt)的天然反义转录物而治疗沉默调节蛋白(sirt)相关疾病
|
MA34291B1
(fr)
|
2010-05-03 |
2013-06-01 |
Genentech Inc |
Compositions et méthodes de diagnostic et de traitement d'une tumeur
|
JP5866106B2
(ja)
|
2010-05-12 |
2016-02-17 |
コロンビア ユニヴァーシティ |
インスリンを産生し分泌する腸内分泌細胞の製造方法
|
TWI531370B
(zh)
|
2010-05-14 |
2016-05-01 |
可娜公司 |
藉由抑制par4天然反股轉錄本治療par4相關疾病
|
US8895528B2
(en)
|
2010-05-26 |
2014-11-25 |
Curna, Inc. |
Treatment of atonal homolog 1 (ATOH1) related diseases by inhibition of natural antisense transcript to ATOH1
|
JP5807221B2
(ja)
*
|
2010-06-28 |
2015-11-10 |
アユミ工業株式会社 |
接合構造体製造方法および加熱溶融処理方法ならびにこれらのシステム
|
CN103068982B
(zh)
|
2010-07-14 |
2017-06-09 |
库尔纳公司 |
通过抑制盘状大同系物(dlg)的天然反义转录物而治疗dlg相关疾病
|
US9504446B2
(en)
|
2010-08-02 |
2016-11-29 |
Guided Therapy Systems, Llc |
Systems and methods for coupling an ultrasound source to tissue
|
WO2012047968A2
(en)
|
2010-10-05 |
2012-04-12 |
Genentech, Inc. |
Mutant smoothened and methods of using the same
|
EP2625274B1
(de)
|
2010-10-06 |
2017-07-19 |
CuRNA, Inc. |
Behandlung sialidase-4-(neu4)-vermittelter erkrankungen durch hemmung des natürlichen antisense-transkripts gegen neu4
|
WO2012048335A2
(en)
|
2010-10-08 |
2012-04-12 |
The University Of North Carolina At Chapel Hill |
Formulation of acoustically activatable particles having low vaporization energy and methods for using same
|
CA2815212A1
(en)
|
2010-10-22 |
2012-04-26 |
Curna, Inc. |
Treatment of alpha-l-iduronidase (idua) related diseases by inhibition of natural antisense transcript to idua
|
JP6073795B2
(ja)
|
2010-10-27 |
2017-02-01 |
カッパーアールエヌエー,インコーポレイテッド |
インターフェロン関連発生制御因子1(ifrd1)への天然アンチセンス転写物の阻害によるifrd1関連疾患の治療
|
WO2012061811A2
(en)
|
2010-11-05 |
2012-05-10 |
Fibrogen, Inc. |
Treatment method for lung remodeling diseases
|
US8857438B2
(en)
|
2010-11-08 |
2014-10-14 |
Ulthera, Inc. |
Devices and methods for acoustic shielding
|
CN103459599B
(zh)
|
2010-11-23 |
2017-06-16 |
库尔纳公司 |
通过抑制nanog的天然反义转录物而治疗nanog相关疾病
|
WO2012106508A1
(en)
|
2011-02-02 |
2012-08-09 |
Pfizer Inc. |
Method of treating keloids or hypertrophic scars using antisense compounds targeting connective tissue growth factor (ctgf)
|
WO2012109495A1
(en)
|
2011-02-09 |
2012-08-16 |
Metabolic Solutions Development Company, Llc |
Cellular targets of thiazolidinediones
|
AU2012242642A1
(en)
|
2011-04-13 |
2013-05-02 |
Ionis Pharmaceuticals, Inc. |
Antisense modulation of PTP1B expression
|
JP6188686B2
(ja)
|
2011-06-09 |
2017-08-30 |
カッパーアールエヌエー,インコーポレイテッド |
フラタキシン(fxn)への天然アンチセンス転写物の阻害によるfxn関連疾患の治療
|
CN103597074A
(zh)
|
2011-06-16 |
2014-02-19 |
Isis制药公司 |
成纤维细胞生长因子受体4表达的反义调节
|
WO2013009784A2
(en)
|
2011-07-10 |
2013-01-17 |
Guided Therapy Systems, Llc |
Systems and method for accelerating healing of implanted material and/or native tissue
|
WO2013012641A1
(en)
|
2011-07-11 |
2013-01-24 |
Guided Therapy Systems, Llc |
Systems and methods for coupling an ultrasound source to tissue
|
CN103814132B
(zh)
|
2011-09-20 |
2018-06-05 |
苏州瑞博生物技术有限公司 |
Gcgr表达的反义调节
|
US20130085139A1
(en)
|
2011-10-04 |
2013-04-04 |
Royal Holloway And Bedford New College |
Oligomers
|
CN103906838A
(zh)
|
2011-10-25 |
2014-07-02 |
Isis制药公司 |
Gccr表达的反义调节
|
US20150031750A1
(en)
|
2012-03-15 |
2015-01-29 |
The Scripps Research Institute |
Treatment of brain derived neurotrophic factor (bdnf) related diseases by inhibition of natural antisense transcript to bdnf
|
US10357450B2
(en)
|
2012-04-06 |
2019-07-23 |
Children's Medical Center Corporation |
Process for forming microbubbles with high oxygen content and uses thereof
|
US9263663B2
(en)
|
2012-04-13 |
2016-02-16 |
Ardent Sound, Inc. |
Method of making thick film transducer arrays
|
EP2844362B1
(de)
|
2012-04-30 |
2020-02-26 |
Ge Healthcare As |
Verfahren zum füllen eines behälters mit einer aufschäumbaren zusammensetzung
|
WO2014041179A1
(en)
|
2012-09-17 |
2014-03-20 |
Chemedest Ltd. |
Treatment of peripheral neuropathy using gfr(alpha)3 type receptor agonists
|
US9510802B2
(en)
|
2012-09-21 |
2016-12-06 |
Guided Therapy Systems, Llc |
Reflective ultrasound technology for dermatological treatments
|
WO2014055832A1
(en)
|
2012-10-04 |
2014-04-10 |
The University Of North Carolina At Chapel Hill |
Methods and systems for using encapsulated microbubbles to process biological samples
|
CN204017181U
(zh)
|
2013-03-08 |
2014-12-17 |
奥赛拉公司 |
美学成像与处理系统、多焦点处理系统和执行美容过程的系统
|
WO2014146022A2
(en)
|
2013-03-15 |
2014-09-18 |
Guided Therapy Systems Llc |
Ultrasound treatment device and methods of use
|
WO2014152497A2
(en)
|
2013-03-15 |
2014-09-25 |
The Trustees Of Columbia University In The City Of New York |
Osteocalcin as a treatment for cognitive disorders
|
WO2014144364A1
(en)
|
2013-03-15 |
2014-09-18 |
Children's Medical Center Corporation |
Gas-filled stabilized particles and methods of use
|
CA2918787A1
(en)
|
2013-06-13 |
2014-12-18 |
George Tachas |
Combination therapy
|
US20150197534A1
(en)
|
2013-09-05 |
2015-07-16 |
Sarepta Therapeutics, Inc. |
Antisense-induced exon2 inclusion in acid alpha-glucosidase
|
WO2015042466A2
(en)
|
2013-09-19 |
2015-03-26 |
The United States Of America, As Represented By The Secretary, Department Of Health & Human Services |
Compositions and methods for inhibiting jc virus (jcv)
|
WO2015116902A1
(en)
|
2014-01-31 |
2015-08-06 |
Genentech, Inc. |
G-protein coupled receptors in hedgehog signaling
|
WO2015120075A2
(en)
|
2014-02-04 |
2015-08-13 |
Genentech, Inc. |
Mutant smoothened and methods of using the same
|
WO2015160708A1
(en)
|
2014-04-18 |
2015-10-22 |
Ulthera, Inc. |
Band transducer ultrasound therapy
|
CA2985344A1
(en)
|
2014-06-26 |
2015-12-30 |
The Trustees Of Columbia University In The City Of New York |
Inhibition of serotonin expression in gut enteroendocrine cells results in conversion to insulin-positive cells
|
WO2016033424A1
(en)
|
2014-08-29 |
2016-03-03 |
Genzyme Corporation |
Methods for the prevention and treatment of major adverse cardiovascular events using compounds that modulate apolipoprotein b
|
WO2016081728A1
(en)
|
2014-11-19 |
2016-05-26 |
The Trustees Of Columbia University In The City Of New York |
Osteocalcin as a treatment for frailty associated with aging
|
JP6373749B2
(ja)
*
|
2014-12-19 |
2018-08-15 |
富士フイルム株式会社 |
リポソームの製造方法及びリポソーム製造装置
|
MX2017008721A
(es)
|
2014-12-31 |
2017-11-17 |
Lantheus Medical Imaging Inc |
Composiciones de microesferas de gas encapsulado en lipidos y metodos relacionados.
|
MA41795A
(fr)
|
2015-03-18 |
2018-01-23 |
Sarepta Therapeutics Inc |
Exclusion d'un exon induite par des composés antisens dans la myostatine
|
CN107580489B
(zh)
*
|
2015-03-26 |
2020-10-16 |
因内博注射剂公司 |
加压气体驱动的药剂转移和再悬浮设备和方法
|
EP3851531A1
(de)
|
2015-06-01 |
2021-07-21 |
Sarepta Therapeutics, Inc. |
Antisense-induzierte exonexklusion in typ-vii-kollagen
|
US9867974B2
(en)
*
|
2015-06-01 |
2018-01-16 |
Wisconsin Alumni Research Foundation |
Microfluidic device for multiplexed point source administration of compounds
|
US10954300B2
(en)
|
2015-09-28 |
2021-03-23 |
The Trustees Of Columbia University In The City Of New York |
Use of pentoxifylline with immune checkpoint-blockade therapies for the treatment of melanoma
|
JP2018530560A
(ja)
|
2015-10-09 |
2018-10-18 |
サレプタ セラピューティクス, インコーポレイテッド |
デュシェンヌ型筋ジストロフィーおよび関連障害の処置のための組成物および方法
|
EP3370734B1
(de)
|
2015-11-05 |
2023-01-04 |
Children's Hospital Los Angeles |
Antisense-oligo zur verwendung bei der behandlung von akuter myeloischer leukämie
|
PL3405294T3
(pl)
|
2016-01-18 |
2023-05-08 |
Ulthera, Inc. |
Kompaktowe urządzenie ultradźwiękowe posiadające pierścieniowy zestaw ultradźwiękowy obwodowo połączony elektrycznie z elastyczną płytką drukowaną
|
CA3019952A1
(en)
|
2016-02-04 |
2017-08-10 |
Curis, Inc. |
Mutant smoothened and methods of using the same
|
KR102522059B1
(ko)
|
2016-04-18 |
2023-04-14 |
사렙타 쎄러퓨틱스 인코퍼레이티드 |
안티센스 올리고머, 및 산성 알파-글루코시다제 유전자와 연관된 질환을 치료하기 위한 이의 사용 방법
|
KR20180133527A
(ko)
|
2016-05-04 |
2018-12-14 |
랜티우스 메디컬 이메징, 인크. |
초음파 조영제의 제조 방법 및 장치
|
US9789210B1
(en)
|
2016-07-06 |
2017-10-17 |
Lantheus Medical Imaging, Inc. |
Methods for making ultrasound contrast agents
|
IL293809B2
(en)
|
2016-08-16 |
2023-09-01 |
Ulthera Inc |
Systems and methods for cosmetic treatment of the skin using ultrasound
|
US11147890B2
(en)
|
2017-02-28 |
2021-10-19 |
Children's Medical Center Corporation |
Stimuli-responsive particles encapsulating a gas and methods of use
|
US10994025B2
(en)
|
2017-05-12 |
2021-05-04 |
Massachusetts Institute Of Technology |
Argonaute protein-double stranded RNA complexes and uses related thereto
|
WO2019079637A2
(en)
|
2017-10-18 |
2019-04-25 |
Sarepta Therapeutics, Inc. |
ANTISENSE OLIGOMERIC COMPOUNDS
|
WO2019164836A1
(en)
|
2018-02-20 |
2019-08-29 |
Ulthera, Inc. |
Systems and methods for combined cosmetic treatment of cellulite with ultrasound
|
US20210155959A1
(en)
|
2018-04-06 |
2021-05-27 |
Children's Medical Center Corporation |
Compositions and methods for somatic cell reprogramming and modulating imprinting
|
CN109231614B
(zh)
*
|
2018-10-30 |
2024-03-29 |
常州市第二人民医院 |
一种医用超声耦合剂废液循环再利用设备
|
AU2022261124A1
(en)
|
2021-04-22 |
2023-10-05 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for treating cancer
|