DE69233351D1 - Multimere der löslichen Formen der TNF-Rezeptoren, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen - Google Patents

Multimere der löslichen Formen der TNF-Rezeptoren, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen

Info

Publication number
DE69233351D1
DE69233351D1 DE69233351T DE69233351T DE69233351D1 DE 69233351 D1 DE69233351 D1 DE 69233351D1 DE 69233351 T DE69233351 T DE 69233351T DE 69233351 T DE69233351 T DE 69233351T DE 69233351 D1 DE69233351 D1 DE 69233351D1
Authority
DE
Germany
Prior art keywords
multimers
soluble forms
processes
preparation
pharmaceutical preparations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69233351T
Other languages
English (en)
Other versions
DE69233351T2 (de
Inventor
David Wallach
Cord Brakebusch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yeda Research and Development Co Ltd
Original Assignee
Yeda Research and Development Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11062796&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69233351(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Yeda Research and Development Co Ltd filed Critical Yeda Research and Development Co Ltd
Publication of DE69233351D1 publication Critical patent/DE69233351D1/de
Application granted granted Critical
Publication of DE69233351T2 publication Critical patent/DE69233351T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/525—Tumour necrosis factor [TNF]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7151—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for tumor necrosis factor [TNF], for lymphotoxin [LT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
DE69233351T 1991-08-07 1992-08-07 Multimere der löslichen Formen der TNF-Rezeptoren, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen Expired - Lifetime DE69233351T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL99120 1991-08-07
IL99120A IL99120A0 (en) 1991-08-07 1991-08-07 Multimers of the soluble forms of tnf receptors,their preparation and pharmaceutical compositions containing them

Publications (2)

Publication Number Publication Date
DE69233351D1 true DE69233351D1 (de) 2004-06-17
DE69233351T2 DE69233351T2 (de) 2005-05-04

Family

ID=11062796

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69233351T Expired - Lifetime DE69233351T2 (de) 1991-08-07 1992-08-07 Multimere der löslichen Formen der TNF-Rezeptoren, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen

Country Status (12)

Country Link
US (1) US5478925A (de)
EP (1) EP0526905B1 (de)
JP (1) JPH07145068A (de)
AT (1) ATE266724T1 (de)
AU (1) AU661008B2 (de)
CA (1) CA2075358C (de)
DE (1) DE69233351T2 (de)
DK (1) DK0526905T3 (de)
ES (1) ES2218518T3 (de)
IL (1) IL99120A0 (de)
PT (1) PT526905E (de)
ZA (1) ZA925904B (de)

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IL99120A0 (en) 1992-07-15
JPH07145068A (ja) 1995-06-06
DK0526905T3 (da) 2004-08-16
EP0526905A2 (de) 1993-02-10
AU661008B2 (en) 1995-07-13
EP0526905A3 (en) 1993-05-05
CA2075358A1 (en) 1993-02-08
US5478925A (en) 1995-12-26
AU2090992A (en) 1993-02-11
ATE266724T1 (de) 2004-05-15
EP0526905B1 (de) 2004-05-12
PT526905E (pt) 2004-09-30
ES2218518T3 (es) 2004-11-16
DE69233351T2 (de) 2005-05-04
ZA925904B (en) 1993-03-25

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