DE69231228D1 - Neuartige polypeptide zur unterstützung der zellfixierung - Google Patents
Neuartige polypeptide zur unterstützung der zellfixierungInfo
- Publication number
- DE69231228D1 DE69231228D1 DE69231228T DE69231228T DE69231228D1 DE 69231228 D1 DE69231228 D1 DE 69231228D1 DE 69231228 T DE69231228 T DE 69231228T DE 69231228 T DE69231228 T DE 69231228T DE 69231228 D1 DE69231228 D1 DE 69231228D1
- Authority
- DE
- Germany
- Prior art keywords
- fibronectin
- polypeptides
- innovative
- cells
- binding site
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/75—Fibrinogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C07K2319/24—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a MBP (maltose binding protein)-tag
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/50—Fusion polypeptide containing protease site
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/61—Fusion polypeptide containing an enzyme fusion for detection (lacZ, luciferase)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/804,224 US5492890A (en) | 1990-12-03 | 1991-12-05 | Polypeptides for promoting cell attachment |
PCT/US1992/010511 WO1993011229A1 (en) | 1991-12-05 | 1992-12-04 | Novel polypeptides for promoting cell attachment |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69231228D1 true DE69231228D1 (de) | 2000-08-10 |
DE69231228T2 DE69231228T2 (de) | 2000-11-30 |
Family
ID=25188472
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69231228T Expired - Lifetime DE69231228T2 (de) | 1991-12-05 | 1992-12-04 | Neuartige polypeptide zur unterstützung der zellfixierung |
Country Status (12)
Country | Link |
---|---|
US (1) | US5492890A (de) |
EP (1) | EP0619839B1 (de) |
JP (2) | JP4272257B2 (de) |
AT (1) | ATE194382T1 (de) |
AU (1) | AU680607B2 (de) |
CA (1) | CA2125174C (de) |
DE (1) | DE69231228T2 (de) |
DK (1) | DK0619839T3 (de) |
ES (1) | ES2147558T3 (de) |
GR (1) | GR3034352T3 (de) |
PT (1) | PT619839E (de) |
WO (1) | WO1993011229A1 (de) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5770198A (en) * | 1988-05-18 | 1998-06-23 | The Research Foundation Of The State Of New York | Platelet-specific chimeric 7E3 immunoglobulin |
US5780303A (en) * | 1990-04-06 | 1998-07-14 | La Jolla Cancer Research Foundation | Method and composition for treating thrombosis |
US6017877A (en) * | 1990-04-06 | 2000-01-25 | La Jolla Cancer Research Foundation | Method and composition for treating thrombosis |
US6521594B1 (en) | 1990-04-06 | 2003-02-18 | La Jolla Cancer Research Foundation | Method and composition for treating thrombosis |
US5672585A (en) * | 1990-04-06 | 1997-09-30 | La Jolla Cancer Research Foundation | Method and composition for treating thrombosis |
US5645815A (en) * | 1991-02-08 | 1997-07-08 | Diatide, Inc. | Radiolabled compounds for thrombus imaging |
US5629291A (en) * | 1992-01-31 | 1997-05-13 | La Jolla Cancer Research Foundation | Methods of modulating fibronectin extracellular matrix assembly |
US5968476A (en) * | 1992-05-21 | 1999-10-19 | Diatide, Inc. | Technetium-99m labeled peptides for thrombus imaging |
US7083979B1 (en) * | 1994-03-25 | 2006-08-01 | Indiana University Foundation | Methods for enhanced retroviral-mediated gene transfer |
US5763270A (en) * | 1995-06-07 | 1998-06-09 | Genemedicine, Inc. | Plasmid for delivery of nucleic acids to cells and methods of use |
JP4365456B2 (ja) * | 1995-09-29 | 2009-11-18 | インディアナ・ユニバーシティ・リサーチ・アンド・テクノロジー・コーポレーション | ウイルス及び細胞結合部位を持つ分子を用いたウイルス媒介性dna導入を増強する方法 |
KR100353115B1 (ko) * | 1995-11-13 | 2003-01-06 | 다카라츠죠 가부시키가이샤 | 레트로바이러스를사용한표적세포내로의유전자도입방법 |
US6242587B1 (en) | 1996-10-02 | 2001-06-05 | The University Of North Carolina At Chapel Hill | DNA molecules encoding a calcium-integrin binding protein |
US6025150A (en) * | 1996-11-21 | 2000-02-15 | The Regents Of The University Of Michigan | Methods and compositions for wound healing |
US6001965A (en) * | 1996-11-21 | 1999-12-14 | The Regents Of The University Of Michigan | Anticancer compounds and methods |
WO1998022617A1 (en) * | 1996-11-21 | 1998-05-28 | The Regents Of The University Of Michigan | Invasion-inducing agents and invasion-inhibitors for use in wound healing and cancer |
US5840514A (en) * | 1996-11-21 | 1998-11-24 | The Regents Of The University Of Michigan | Methods of testing cancer and anticancer drugs |
US6331409B1 (en) | 1996-11-21 | 2001-12-18 | The Regents Of The University Of Michigan | Methods and compositions for wound healing |
AU3192299A (en) * | 1998-03-18 | 1999-10-11 | Wake Forest University | Improved implantable biomaterials, compositions and methods for their preparation and uses thereof |
CA2340595A1 (en) * | 1998-08-25 | 2000-03-02 | University Of Washington | Streptavidin mutants having secondary functional domains |
US20160287708A9 (en) * | 2000-03-15 | 2016-10-06 | Orbusneich Medical, Inc. | Progenitor Endothelial Cell Capturing with a Drug Eluting Implantable Medical Device |
US9522217B2 (en) * | 2000-03-15 | 2016-12-20 | Orbusneich Medical, Inc. | Medical device with coating for capturing genetically-altered cells and methods for using same |
US20050271701A1 (en) * | 2000-03-15 | 2005-12-08 | Orbus Medical Technologies, Inc. | Progenitor endothelial cell capturing with a drug eluting implantable medical device |
US7037332B2 (en) * | 2000-03-15 | 2006-05-02 | Orbus Medical Technologies, Inc. | Medical device with coating that promotes endothelial cell adherence |
US8460367B2 (en) * | 2000-03-15 | 2013-06-11 | Orbusneich Medical, Inc. | Progenitor endothelial cell capturing with a drug eluting implantable medical device |
US8088060B2 (en) * | 2000-03-15 | 2012-01-03 | Orbusneich Medical, Inc. | Progenitor endothelial cell capturing with a drug eluting implantable medical device |
US6864065B2 (en) * | 2000-11-08 | 2005-03-08 | Surface Logix, Inc. | Assays for monitoring cell motility in real-time |
US7033819B2 (en) | 2000-11-08 | 2006-04-25 | Surface Logix, Inc. | System for monitoring cell motility in real-time |
US6893851B2 (en) | 2000-11-08 | 2005-05-17 | Surface Logix, Inc. | Method for arraying biomolecules and for monitoring cell motility in real-time |
US6699665B1 (en) * | 2000-11-08 | 2004-03-02 | Surface Logix, Inc. | Multiple array system for integrating bioarrays |
US7374906B2 (en) | 2000-11-08 | 2008-05-20 | Surface Logix, Inc. | Biological assays using gradients formed in microfluidic systems |
US7033821B2 (en) * | 2000-11-08 | 2006-04-25 | Surface Logix, Inc. | Device for monitoring cell motility in real-time |
US6844184B2 (en) * | 2000-11-08 | 2005-01-18 | Surface Logix, Inc. | Device for arraying biomolecules and for monitoring cell motility in real-time |
US7326563B2 (en) | 2000-11-08 | 2008-02-05 | Surface Logix, Inc. | Device and method for monitoring leukocyte migration |
JP4590117B2 (ja) * | 2001-02-21 | 2010-12-01 | 森永製菓株式会社 | 免疫測定試薬 |
US20030082148A1 (en) * | 2001-10-31 | 2003-05-01 | Florian Ludwig | Methods and device compositions for the recruitment of cells to blood contacting surfaces in vivo |
US20060078535A1 (en) * | 2004-10-13 | 2006-04-13 | The Regents Of The University Of Michigan | Anticancer compounds and methods |
US8921516B2 (en) * | 2010-12-08 | 2014-12-30 | Corning Incorporated | Synthetic, defined fibronectin mimetic peptides and surfaces modified with the same |
CN111454350B (zh) * | 2020-06-01 | 2020-12-29 | 广东丸美生物技术股份有限公司 | 一种重组纤连蛋白突变体及其应用 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0114887B1 (de) * | 1982-08-04 | 1990-11-28 | La Jolla Cancer Research Foundation | Polypeptide |
US4792525A (en) * | 1982-08-04 | 1988-12-20 | La Jolla Cancer Research Foundation | Tetrapeptide |
US4578079A (en) * | 1982-08-04 | 1986-03-25 | La Jolla Cancer Research Foundation | Tetrapeptide |
US4980279A (en) * | 1986-04-15 | 1990-12-25 | Scripps Clinic And Research Foundation | Cellular fibronectin: polypeptides, anti-polypeptide antibodies and assay methods |
US5019646A (en) * | 1987-08-25 | 1991-05-28 | Regents Of The University Of Minnesota | Polypeptides with fibronectin activity |
JPH0829098B2 (ja) * | 1988-01-05 | 1996-03-27 | 寳酒造株式会社 | 細胞接着活性ポリペプチド |
US5773574A (en) * | 1990-12-03 | 1998-06-30 | The Scripps Research Institute | Polypeptides for promoting cell attachment |
AU1515392A (en) * | 1991-04-26 | 1992-10-29 | Mark Rossi | Method and apparatus for cane trash removal |
US5453489A (en) * | 1992-01-31 | 1995-09-26 | La Jolla Cancer Research Foundation | Polypeptide fragments of fibronectin which can modulate extracellular matrix assembly |
-
1991
- 1991-12-05 US US07/804,224 patent/US5492890A/en not_active Expired - Lifetime
-
1992
- 1992-12-04 DK DK93900897T patent/DK0619839T3/da active
- 1992-12-04 AT AT93900897T patent/ATE194382T1/de active
- 1992-12-04 DE DE69231228T patent/DE69231228T2/de not_active Expired - Lifetime
- 1992-12-04 EP EP93900897A patent/EP0619839B1/de not_active Expired - Lifetime
- 1992-12-04 CA CA002125174A patent/CA2125174C/en not_active Expired - Lifetime
- 1992-12-04 AU AU32408/93A patent/AU680607B2/en not_active Expired
- 1992-12-04 JP JP51037493A patent/JP4272257B2/ja not_active Expired - Lifetime
- 1992-12-04 PT PT93900897T patent/PT619839E/pt unknown
- 1992-12-04 ES ES93900897T patent/ES2147558T3/es not_active Expired - Lifetime
- 1992-12-04 WO PCT/US1992/010511 patent/WO1993011229A1/en active IP Right Grant
-
2000
- 2000-09-06 GR GR20000402040T patent/GR3034352T3/el unknown
-
2007
- 2007-07-25 JP JP2007193288A patent/JP2007312788A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
AU680607B2 (en) | 1997-08-07 |
EP0619839A1 (de) | 1994-10-19 |
EP0619839B1 (de) | 2000-07-05 |
WO1993011229A1 (en) | 1993-06-10 |
AU3240893A (en) | 1993-06-28 |
DE69231228T2 (de) | 2000-11-30 |
ATE194382T1 (de) | 2000-07-15 |
JP2007312788A (ja) | 2007-12-06 |
CA2125174A1 (en) | 1993-06-10 |
DK0619839T3 (da) | 2000-09-18 |
US5492890A (en) | 1996-02-20 |
ES2147558T3 (es) | 2000-09-16 |
EP0619839A4 (en) | 1995-09-20 |
GR3034352T3 (en) | 2000-12-29 |
PT619839E (pt) | 2000-10-31 |
JPH07504812A (ja) | 1995-06-01 |
CA2125174C (en) | 2007-04-10 |
JP4272257B2 (ja) | 2009-06-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |