DE69220808D1 - Vorrichtung zur verabreichung von heilmitteln - Google Patents

Vorrichtung zur verabreichung von heilmitteln

Info

Publication number
DE69220808D1
DE69220808D1 DE69220808T DE69220808T DE69220808D1 DE 69220808 D1 DE69220808 D1 DE 69220808D1 DE 69220808 T DE69220808 T DE 69220808T DE 69220808 T DE69220808 T DE 69220808T DE 69220808 D1 DE69220808 D1 DE 69220808D1
Authority
DE
Germany
Prior art keywords
drug
electrode
pct
skin
reservoir
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69220808T
Other languages
English (en)
Other versions
DE69220808T2 (de
Inventor
John Corish
Owen Ignatius Corrigan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Elan Pharma International Ltd
Original Assignee
Elan Corp PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elan Corp PLC filed Critical Elan Corp PLC
Application granted granted Critical
Publication of DE69220808D1 publication Critical patent/DE69220808D1/de
Publication of DE69220808T2 publication Critical patent/DE69220808T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/20Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A61N1/303Constructional details

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Electrotherapy Devices (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69220808T 1991-11-13 1992-11-10 Vorrichtung zur verabreichung von heilmitteln Expired - Lifetime DE69220808T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IE394191 1991-11-13
PCT/IE1992/000021 WO1993009842A1 (en) 1991-11-13 1992-11-10 Drug delivery device

Publications (2)

Publication Number Publication Date
DE69220808D1 true DE69220808D1 (de) 1997-08-14
DE69220808T2 DE69220808T2 (de) 1998-01-02

Family

ID=11039234

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69220808T Expired - Lifetime DE69220808T2 (de) 1991-11-13 1992-11-10 Vorrichtung zur verabreichung von heilmitteln

Country Status (11)

Country Link
US (1) US5533995A (de)
EP (1) EP0612258B1 (de)
JP (1) JP3456994B2 (de)
AT (1) ATE155045T1 (de)
AU (1) AU664214B2 (de)
CA (1) CA2123428A1 (de)
DE (1) DE69220808T2 (de)
IL (1) IL103711A (de)
NZ (1) NZ245091A (de)
WO (1) WO1993009842A1 (de)
ZA (1) ZA928689B (de)

Families Citing this family (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995025562A1 (en) * 1992-06-02 1995-09-28 Alza Corporation Electrotransport drug delivery device
SE501638C2 (sv) * 1993-08-17 1995-04-03 Perimed Ab Anordning för jontoforetisk administrering, innefattande minst en laser-dopplerprobe, samt användning av anordningen
KR0134151B1 (ko) * 1994-05-23 1998-04-14 이형도 인슐린 패치
FR2726769B1 (fr) * 1994-11-16 1997-01-31 Lhd Lab Hygiene Dietetique Dispositif ionophoretique d'administration transdermique de medicaments et ensemble jetable formant partie d'un tel dispositif
US5866629A (en) * 1995-12-05 1999-02-02 The University Of Toronto Innovations Foundation Dental and medical primer formulations containing tissue infiltrating agents
US7070590B1 (en) * 1996-07-02 2006-07-04 Massachusetts Institute Of Technology Microchip drug delivery devices
US6797276B1 (en) 1996-11-14 2004-09-28 The United States Of America As Represented By The Secretary Of The Army Use of penetration enhancers and barrier disruption agents to enhance the transcutaneous immune response
US5980898A (en) 1996-11-14 1999-11-09 The United States Of America As Represented By The U.S. Army Medical Research & Material Command Adjuvant for transcutaneous immunization
US20060002949A1 (en) 1996-11-14 2006-01-05 Army Govt. Of The Usa, As Rep. By Secretary Of The Office Of The Command Judge Advocate, Hq Usamrmc. Transcutaneous immunization without heterologous adjuvant
US5971722A (en) * 1997-09-05 1999-10-26 Baxter International Inc Electrochemical syringe pump having a sealed storage reservoir for a charge transfer medium
US6757560B1 (en) * 1999-04-09 2004-06-29 Novosis Pharma Ag Transdermal delivery system (TDS) with electrode network
WO2000061184A2 (en) * 1999-04-08 2000-10-19 Glenn Gregory M Dry formulation for transcutaneous immunization
EP1229901B1 (de) * 1999-11-17 2009-03-18 Boston Scientific Limited Miniaturisierte vorrichtungen zur abgabe von molekülen in einer trägerflüssigkeit
ATE323470T1 (de) * 1999-12-10 2006-05-15 Massachusetts Inst Technology Mikrochip-arzneistoffverabreichungssysteme und herstellungsverfahren
ATE499988T1 (de) * 2000-03-02 2011-03-15 Microchips Inc Mikromechanische geräte und verfahren zur speicherung und zur selektiven exposition von chemikalien
EP1339312B1 (de) * 2000-10-10 2006-01-04 Microchips, Inc. Mikrochip-reservoir-vorrichtungen mit drahtloser übertragung von energie und daten
CA2432438C (en) 2001-01-09 2011-04-26 Microchips, Inc. Flexible microchip devices for ophthalmic and other applications
ES2310201T3 (es) 2001-02-13 2009-01-01 Government Of The United States Of America, As Represented By The Secretary Of The Army Vacuna para inmunizacion transcutanea contra la diarrea de los viajeros.
RU2290216C2 (ru) * 2001-04-04 2006-12-27 Алза Корпорейшн Устройство для трансдермального электротранспортного введения, содержащее резервуар с противомикробной совместимой композицией
AU2002326304A1 (en) * 2001-05-31 2002-12-16 Massachusetts Institute Of Technology Microchip devices with improved reservoir opening
ATE285756T1 (de) * 2001-06-28 2005-01-15 Microchips Inc Verfahren zum hermetischen versiegeln von mikrochip-reservoir-vorrichtungen
US7429258B2 (en) * 2001-10-26 2008-09-30 Massachusetts Institute Of Technology Microneedle transport device
US7115108B2 (en) * 2002-04-02 2006-10-03 Becton, Dickinson And Company Method and device for intradermally delivering a substance
US6975902B2 (en) * 2002-06-28 2005-12-13 Alza Corporation Reservoir and a series of related reservoirs for use in an electrotransport drug delivery device and devices comprised thereof
WO2004071487A2 (en) * 2002-08-16 2004-08-26 Microchips, Inc. Controlled release device and method
WO2004026281A2 (en) * 2002-09-23 2004-04-01 Microchips, Inc. Micro-reservoir osmotic release systems and microtube array device
CA2506129C (en) 2002-11-15 2015-02-17 Idenix (Cayman) Limited 2'-branched nucleosides and flaviviridae mutation
DE50307646D1 (de) * 2003-03-12 2007-08-23 Novosis Ag Transdermales Wirkstoffverabreichungssystem mit Elektrodenraster
US20050055014A1 (en) * 2003-08-04 2005-03-10 Coppeta Jonathan R. Methods for accelerated release of material from a reservoir device
WO2005041767A2 (en) * 2003-11-03 2005-05-12 Microchips, Inc. Medical device for sensing glucose
IL159273A0 (en) * 2003-12-09 2004-06-01 Transpharma Medical Ltd Transdermal delivery system for sustained release of polypeptides
PL1729746T3 (pl) * 2004-03-19 2010-03-31 Mcneil Ab Środki do przezskórnego podawania nikotyny
US20050267440A1 (en) * 2004-06-01 2005-12-01 Herman Stephen J Devices and methods for measuring and enhancing drug or analyte transport to/from medical implant
US20080280973A1 (en) * 2004-06-28 2008-11-13 Wender Paul A Laulimalide Analogues as Therapeutic Agents
WO2006015299A2 (en) * 2004-07-30 2006-02-09 Microchips, Inc. Multi-reservoir device for transdermal drug delivery and sensing
WO2006026768A1 (en) * 2004-09-01 2006-03-09 Microchips, Inc. Multi-cap reservoir devices for controlled release or exposure of reservoir contents
US7413846B2 (en) * 2004-11-15 2008-08-19 Microchips, Inc. Fabrication methods and structures for micro-reservoir devices
US7488316B2 (en) * 2005-01-25 2009-02-10 Microchips, Inc. Control of drug release by transient modification of local microenvironments
US20080076975A1 (en) * 2005-01-25 2008-03-27 Microchips, Inc. Method and implantable device with reservoir array for pre-clinical in vivo testing
DE602006017807D1 (de) * 2005-02-11 2010-12-09 Massachusetts Inst Technology Oberflächeninjizierungsvorrichtung
US7833189B2 (en) * 2005-02-11 2010-11-16 Massachusetts Institute Of Technology Controlled needle-free transport
US20060258986A1 (en) * 2005-02-11 2006-11-16 Hunter Ian W Controlled needle-free transport
WO2007058966A1 (en) * 2005-11-11 2007-05-24 Massachusetts Institute Of Technology Controlled needle-free eye injector
US20070275035A1 (en) * 2006-05-24 2007-11-29 Microchips, Inc. Minimally Invasive Medical Implant Devices for Controlled Drug Delivery
EP2077877B1 (de) * 2006-09-01 2019-12-11 Massachusetts Institute of Technology Nadelfreies injektionsgerät mit automatischer ladbarkeit
WO2009000262A1 (de) * 2007-06-25 2008-12-31 Acino Ag Elektrophoretisches transdermales applikationssystem
US8398583B2 (en) 2008-07-09 2013-03-19 Massachusetts Institute Of Technology Method and apparatus for extraction of a sample from a sample source
EP2401027B1 (de) 2009-02-26 2017-11-01 The University of North Carolina At Chapel Hill Interventionelles arzneimittelabgabesystem
US8758271B2 (en) 2009-09-01 2014-06-24 Massachusetts Institute Of Technology Nonlinear system identification techniques and devices for discovering dynamic and static tissue properties
WO2011075535A1 (en) 2009-12-15 2011-06-23 Massachusetts Institute Of Technology Plaque removal and differentiation of tooth and gum
DE102010024558B4 (de) 2010-06-22 2016-04-21 Amw Gmbh Transdermales therapeutisches System mit Elektroden
CN104185420B (zh) 2011-11-30 2017-06-09 埃默里大学 用于治疗或预防逆转录病毒和其它病毒感染的抗病毒jak抑制剂
EP2874693A1 (de) 2012-07-20 2015-05-27 Grünenthal GmbH Durch ein elektrisches feld unterstützte verabreichung von tapentadol
CA2942078C (en) 2014-03-14 2023-03-14 The University Of North Carolina At Chapel Hill Small molecules for inhibiting male fertility
KR101887088B1 (ko) * 2017-02-28 2018-08-09 (주)강앤박메디컬 무 바늘 용액 주입 장치 및 이를 이용한 무 바늘 용액 주입 방법
EP3600263B1 (de) 2017-03-24 2024-01-03 E Ink Corporation Mikrozellensysteme zur abgabe von aktiven molekülen
WO2018175829A1 (en) 2017-03-24 2018-09-27 E Ink California, Llc Microcell delivery systems including charged or magnetic particles for regulating rate of administration of actives
CN111295182A (zh) 2017-11-14 2020-06-16 伊英克加利福尼亚有限责任公司 包括多孔导电电极层的电泳活性物质递送系统
US11938214B2 (en) 2019-11-27 2024-03-26 E Ink Corporation Benefit agent delivery system comprising microcells having an electrically eroding sealing layer
EP4236926A1 (de) 2020-10-29 2023-09-06 E Ink California, LLC Mikrozellensysteme zur abgabe von vorteilhaften mitteln
CN116507322A (zh) 2020-10-29 2023-07-28 伊英克加利福尼亚有限责任公司 用于递送亲水活性分子的微单元系统

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3923426A (en) * 1974-08-15 1975-12-02 Alza Corp Electroosmotic pump and fluid dispenser including same
US4639244A (en) * 1983-05-03 1987-01-27 Nabil I. Rizk Implantable electrophoretic pump for ionic drugs and associated methods
US4722726A (en) * 1986-02-12 1988-02-02 Key Pharmaceuticals, Inc. Method and apparatus for iontophoretic drug delivery
US4731049A (en) * 1987-01-30 1988-03-15 Ionics, Incorporated Cell for electrically controlled transdermal drug delivery
US4942883A (en) * 1987-09-29 1990-07-24 Newman Martin H Drug delivery device
US4943435A (en) * 1987-10-05 1990-07-24 Pharmetrix Corporation Prolonged activity nicotine patch
CA2001446C (en) * 1988-10-28 2000-08-01 Joseph Bradley Phipps Iontophoresis electrode
US5041107A (en) * 1989-10-06 1991-08-20 Cardiac Pacemakers, Inc. Electrically controllable, non-occluding, body implantable drug delivery system
IT1244030B (it) * 1989-12-21 1994-06-28 Elan Corp Plc Dispostitivo in due parti per la somministrazione controllata di un ingrediente
US5156591A (en) * 1990-12-13 1992-10-20 S. I. Scientific Innovations Ltd. Skin electrode construction and transdermal drug delivery device utilizing same
IL97099A0 (en) * 1991-01-30 1992-03-29 Scient Innovations Ltd Infusion pump with safety means controlling the electrolytic cell
US5356632A (en) * 1991-09-12 1994-10-18 S.I. Scientific Innovations Ltd. Transdermal drug delivery device

Also Published As

Publication number Publication date
CA2123428A1 (en) 1993-05-27
AU664214B2 (en) 1995-11-09
JP3456994B2 (ja) 2003-10-14
JPH07500991A (ja) 1995-02-02
NZ245091A (en) 1994-03-25
AU2909992A (en) 1993-06-15
WO1993009842A1 (en) 1993-05-27
IL103711A (en) 1997-02-18
EP0612258B1 (de) 1997-07-09
DE69220808T2 (de) 1998-01-02
ZA928689B (en) 1993-05-10
US5533995A (en) 1996-07-09
EP0612258A1 (de) 1994-08-31
ATE155045T1 (de) 1997-07-15
IL103711A0 (en) 1993-04-04

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: ELAN PHARMA INTERNATIONAL LTD., ATHLONE, WESTM, IE

R071 Expiry of right

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