DE69131797T2 - Systeme und verfahren zum gleichzeitigen entfernen von freien und gebundenen verunreinigungen aus flüssigkeiten, wie blut, mit hilfe einer photoaktiven therapie sowie zellseparationstechniken - Google Patents
Systeme und verfahren zum gleichzeitigen entfernen von freien und gebundenen verunreinigungen aus flüssigkeiten, wie blut, mit hilfe einer photoaktiven therapie sowie zellseparationstechnikenInfo
- Publication number
- DE69131797T2 DE69131797T2 DE69131797T DE69131797T DE69131797T2 DE 69131797 T2 DE69131797 T2 DE 69131797T2 DE 69131797 T DE69131797 T DE 69131797T DE 69131797 T DE69131797 T DE 69131797T DE 69131797 T2 DE69131797 T2 DE 69131797T2
- Authority
- DE
- Germany
- Prior art keywords
- tied
- liquids
- impurities
- aid
- blood
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
- A61L2/022—Filtration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
- A61L2/08—Radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0209—Multiple bag systems for separating or storing blood components
- A61M1/0218—Multiple bag systems for separating or storing blood components with filters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3681—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3681—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
- A61M1/3683—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation using photoactive agents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/08—Processes employing the direct application of electric or wave energy, or particle radiation; Apparatus therefor
- B01J19/12—Processes employing the direct application of electric or wave energy, or particle radiation; Apparatus therefor employing electromagnetic waves
- B01J19/122—Incoherent waves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3679—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by absorption
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/04—Liquids
- A61M2202/0413—Blood
- A61M2202/0439—White blood cells; Leucocytes
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US63086490A | 1990-12-20 | 1990-12-20 | |
PCT/US1991/009710 WO1992011059A1 (en) | 1990-12-20 | 1991-12-20 | Systems and methods for simultaneously removing free and entrained contaminants in fluids like blood using photoactive therapy and cellular separation techniques |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69131797D1 DE69131797D1 (de) | 1999-12-30 |
DE69131797T2 true DE69131797T2 (de) | 2000-06-29 |
Family
ID=24528866
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69131797T Expired - Fee Related DE69131797T2 (de) | 1990-12-20 | 1991-12-20 | Systeme und verfahren zum gleichzeitigen entfernen von freien und gebundenen verunreinigungen aus flüssigkeiten, wie blut, mit hilfe einer photoaktiven therapie sowie zellseparationstechniken |
Country Status (7)
Country | Link |
---|---|
US (1) | US5536238A (de) |
EP (1) | EP0516839B1 (de) |
JP (1) | JP3051998B2 (de) |
AU (1) | AU648631B2 (de) |
CA (1) | CA2074830C (de) |
DE (1) | DE69131797T2 (de) |
WO (1) | WO1992011059A1 (de) |
Families Citing this family (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2074806A1 (en) * | 1990-12-20 | 1992-06-21 | Ludwig Wolf Jr. | Systems for eradicating contaminants in fluids |
US5935092A (en) * | 1990-12-20 | 1999-08-10 | Baxter International Inc. | Systems and methods for removing free and entrained contaminants in plasma |
ZA919934B (en) * | 1990-12-20 | 1992-09-30 | Baxter Int | Systems and methods for eradicating contaminants using photoactive materials in fluids like blood using discrete sources of radiation |
US5690835A (en) | 1991-12-23 | 1997-11-25 | Baxter International Inc. | Systems and methods for on line collection of cellular blood components that assure donor comfort |
US5547591A (en) * | 1993-06-01 | 1996-08-20 | Asahi Medical Co., Ltd. | Method for separating a blood material into blood components by centrifugation, and centrifugal apparatus |
FR2712493B1 (fr) * | 1993-11-16 | 1996-01-19 | Centre Nat Rech Scient | Utilisation de photosensibilisateurs dérivés du noyau phorbine pour la décontamination du sang infecté par des parasites et/ou des virus. |
US5660731A (en) * | 1994-11-08 | 1997-08-26 | Pall Corporation | Filter for separating photoactive agent |
US5628727A (en) * | 1995-08-15 | 1997-05-13 | Hakky; Said I. | Extracorporeal virioncidal apparatus |
US5865785A (en) * | 1996-02-23 | 1999-02-02 | Baxter International Inc. | Systems and methods for on line finishing of cellular blood products like platelets harvested for therapeutic purposes |
EP0793970A1 (de) * | 1996-03-08 | 1997-09-10 | Rotkreuzstiftung Zentrallaboratorium Blutspendedienst Srk | Photodynamische Inaktivierung von Viren |
US6190855B1 (en) * | 1996-10-28 | 2001-02-20 | Baxter International Inc. | Systems and methods for removing viral agents from blood |
US6168718B1 (en) | 1996-11-08 | 2001-01-02 | Pall Corporation | Method for purifying blood plasma and apparatus suitable therefor |
US5922278A (en) * | 1996-11-19 | 1999-07-13 | Baxter International Inc. | Method and apparatus for inactivating contaminants in biological fluid |
US6190609B1 (en) | 1996-11-19 | 2001-02-20 | Baxter International Inc. | Methods and apparatus for inactivating contaminants in biological fluid |
US5954971A (en) * | 1997-01-07 | 1999-09-21 | Haemonetics Corporation | Pumped-filter blood-processing apparatus and methods |
US6258577B1 (en) | 1998-07-21 | 2001-07-10 | Gambro, Inc. | Method and apparatus for inactivation of biological contaminants using endogenous alloxazine or isoalloxazine photosensitizers |
US20030215784A1 (en) * | 1998-07-21 | 2003-11-20 | Dumont Larry Joe | Method and apparatus for inactivation of biological contaminants using photosensitizers |
US6277337B1 (en) | 1998-07-21 | 2001-08-21 | Gambro, Inc. | Method and apparatus for inactivation of biological contaminants using photosensitizers |
US6058876A (en) * | 1998-09-17 | 2000-05-09 | Keene; Douglas | Blood type-specific safety labeling system for patients and blood products |
US7445756B2 (en) * | 1999-06-03 | 2008-11-04 | Fenwal, Inc. | Fluid processing sets and organizers for the same |
US7068361B2 (en) * | 1999-06-03 | 2006-06-27 | Baxter International | Apparatus, systems and methods for processing and treating a biological fluid with light |
US7025877B1 (en) * | 1999-06-03 | 2006-04-11 | Baxter International Inc. | Processing set for processing and treating a biological fluid |
US6565802B1 (en) | 1999-06-03 | 2003-05-20 | Baxter International Inc. | Apparatus, systems and methods for processing and treating a biological fluid with light |
US7220747B2 (en) * | 1999-07-20 | 2007-05-22 | Gambro, Inc. | Method for preventing damage to or rejuvenating a cellular blood component using mitochondrial enhancer |
US7651474B2 (en) | 1999-10-01 | 2010-01-26 | Caridianbct, Inc. | Method and apparatus for leukoreduction of red blood cells |
US6268120B1 (en) | 1999-10-19 | 2001-07-31 | Gambro, Inc. | Isoalloxazine derivatives to neutralize biological contaminants |
US7985588B2 (en) | 2000-06-02 | 2011-07-26 | Caridianbct Biotechnologies, Llc | Induction of and maintenance of nucleic acid damage in pathogens using riboflavin and light |
TW590780B (en) | 2000-06-02 | 2004-06-11 | Gambro Inc | Additive solutions containing riboflavin |
US7648699B2 (en) | 2000-06-02 | 2010-01-19 | Caridianbct Biotechnologies, Llc | Preventing transfusion related complications in a recipient of a blood transfusion |
US9044523B2 (en) | 2000-06-15 | 2015-06-02 | Terumo Bct, Inc. | Reduction of contaminants in blood and blood products using photosensitizers and peak wavelengths of light |
US20030228564A1 (en) * | 2001-05-30 | 2003-12-11 | Edrich Richard Alan | Nitric oxide in a pathogen inactivation process |
US7264608B2 (en) * | 2001-12-05 | 2007-09-04 | Fenwal, Inc. | Manual processing systems and methods for providing blood components conditioned for pathogen inactivation |
US7052606B2 (en) * | 2001-12-10 | 2006-05-30 | Gambro, Inc. | Methods and apparatus for leukoreduction of red blood cells |
US6994790B2 (en) * | 2002-02-01 | 2006-02-07 | Gambro, Inc. | Whole blood collection and processing method |
US20050026111A1 (en) * | 2003-07-31 | 2005-02-03 | George Nikolov | Sterilizable lower mandibular tooth extraction forceps |
US20060183076A1 (en) * | 2003-02-24 | 2006-08-17 | George Nikolov | Sterilizable lower mandibular tooth extraction forceps |
US20060183077A1 (en) * | 2003-02-24 | 2006-08-17 | George Nikolov | Brush and sterilizable tooth extraction forceps |
US20050080373A1 (en) * | 2003-10-09 | 2005-04-14 | Xiaoling Wang | Apparatus and a method for treating blood related illnesses |
US20050137517A1 (en) * | 2003-12-19 | 2005-06-23 | Baxter International Inc. | Processing systems and methods for providing leukocyte-reduced blood components conditioned for pathogen inactivation |
JP4899040B2 (ja) * | 2005-07-01 | 2012-03-21 | 国立大学法人 岡山大学 | ビリルビン変性器及びビリルビン透析装置 |
EP1933899A1 (de) * | 2005-10-05 | 2008-06-25 | Gambro BCT, Inc. | Verfahren und gerät für die leukoreduktion von roten blutkörperchen |
CN101868255A (zh) * | 2007-08-01 | 2010-10-20 | 科安比司特生物技术有限责任公司 | 全血的病原体灭活 |
WO2009026073A1 (en) * | 2007-08-22 | 2009-02-26 | Caridianbct Biotechnologies, Llc | Prevention of transfusion related acute lung injury using riboflavin and light |
US8835104B2 (en) | 2007-12-20 | 2014-09-16 | Fenwal, Inc. | Medium and methods for the storage of platelets |
AU2012240016B2 (en) | 2011-04-07 | 2016-11-10 | Fenwal, Inc. | Automated methods and systems for providing platelet concentrates with reduced residual plasma volumes and storage media for such platelet concentrates |
Family Cites Families (37)
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US2308516A (en) * | 1939-05-01 | 1943-01-19 | Emmet K Knott | Method and means for irradiating blood |
US3462361A (en) * | 1965-05-14 | 1969-08-19 | Milwaukee Blood Center Inc | Method and apparatus for treating blood |
US4181128A (en) * | 1975-11-28 | 1980-01-01 | Massachusetts Institute Of Technology | Virus inactivation applicator and the like |
US4305390A (en) * | 1975-11-28 | 1981-12-15 | Massachusetts Institute Of Technology | Method for generating oxygen in an excited electronic state and inactivation of microorganisms |
US4398906A (en) * | 1979-12-11 | 1983-08-16 | Frederic A. Bourke, Jr. | Method for externally treating the blood |
US4428744A (en) * | 1979-12-11 | 1984-01-31 | Frederic A. Bourke, Jr. | Method and system for externally treating the blood |
US4321919A (en) * | 1979-12-11 | 1982-03-30 | Leukocyte Research, Inc. | Method and system for externally treating human blood |
US4612007A (en) * | 1981-06-16 | 1986-09-16 | Edelson Richard Leslie | Method and system for externally treating the blood |
US4456512A (en) * | 1982-03-10 | 1984-06-26 | The Dow Chemical Company | Photochemical reactor and method |
US4596657A (en) * | 1982-06-04 | 1986-06-24 | Miles Laboratories, Inc. | Blood bag system with integral filtering means |
US4649151A (en) * | 1982-09-27 | 1987-03-10 | Health Research, Inc. | Drugs comprising porphyrins |
US4613322A (en) * | 1982-12-08 | 1986-09-23 | Edelson Richard Leslie | Method and system for externally treating the blood |
US4684521A (en) * | 1982-12-08 | 1987-08-04 | Frederic A. Bourke, Jr. | Method and system for externally treating the blood |
US4683889A (en) * | 1983-03-29 | 1987-08-04 | Frederic A. Bourke, Jr. | Method and system for externally treating the blood |
US4727027A (en) * | 1983-05-02 | 1988-02-23 | Diamond Scientific Co. | Photochemical decontamination treatment of whole blood or blood components |
CA1253115A (en) * | 1983-09-29 | 1989-04-25 | Extracorporeal Medical Specialties, Inc. | Apparatus and methods for treating cells with radiation |
US4705498A (en) * | 1984-10-29 | 1987-11-10 | Mcneilab, Inc. | Disposable temperature probe for photoactivation patient treatment system |
US4737140A (en) * | 1984-10-29 | 1988-04-12 | Mcneilab, Inc. | Irradiation chamber for photoactivation patient treatment system |
US4708715A (en) * | 1984-10-29 | 1987-11-24 | Mcneilab, Inc. | Light array assembly for photoactivation patient treatment system |
US4573962A (en) * | 1984-10-29 | 1986-03-04 | Extracorporeal Medical Specialties, Inc. | Cassette drawer assembly for photoactivation patient treatment system |
US4683989A (en) * | 1986-02-14 | 1987-08-04 | Westinghouse Electric Corp. | Elevator communication controller |
US4787883A (en) * | 1986-03-10 | 1988-11-29 | Kroyer K K K | Extracorporal thermo-therapy device and method for curing diseases |
US4769131A (en) * | 1986-05-09 | 1988-09-06 | Pure Water Technologies | Ultraviolet radiation purification system |
JPS63111886A (ja) * | 1986-10-29 | 1988-05-17 | 呉羽化学工業株式会社 | 光ダイオ−ドを用いた癌治療装置 |
US4775625A (en) * | 1986-11-21 | 1988-10-04 | The Medical College Of Wisconsin, Inc. | Inactivating enveloped viruses with a merocyanine dye |
US4838852A (en) * | 1987-03-27 | 1989-06-13 | Therakos, Inc. | Active specific immune suppression |
US4878891A (en) * | 1987-06-25 | 1989-11-07 | Baylor Research Foundation | Method for eradicating infectious biological contaminants in body tissues |
US5032241A (en) * | 1987-09-04 | 1991-07-16 | Nutech Energy Systems Inc. | Fluid purification |
US4915638A (en) * | 1988-04-29 | 1990-04-10 | Anthony Domian | Protective enclosure for electrical outlets |
US4950225A (en) * | 1988-09-22 | 1990-08-21 | American Immuno Tech, Inc. | Method for extracorporeal blood shear treatment |
US5078673A (en) * | 1988-11-14 | 1992-01-07 | Neorx Corporation | Selective removal of radiolabeled antibodies |
US4921473A (en) * | 1989-02-02 | 1990-05-01 | Therakos, Inc. | Multicomponent fluid separation and irradiation system |
US4983307A (en) * | 1989-08-02 | 1991-01-08 | Serres Naturtek Greenhouses Inc. | Method for sterilizing liquids by ultraviolet radiation |
US4997577A (en) * | 1989-12-20 | 1991-03-05 | Baxter International Inc. | Systems and methods for removing undesired matter from blood cells |
US5069885A (en) * | 1990-04-23 | 1991-12-03 | Ritchie David G | Photocatalytic fluid purification apparatus having helical nontransparent substrate |
CA2074806A1 (en) * | 1990-12-20 | 1992-06-21 | Ludwig Wolf Jr. | Systems for eradicating contaminants in fluids |
ZA919934B (en) * | 1990-12-20 | 1992-09-30 | Baxter Int | Systems and methods for eradicating contaminants using photoactive materials in fluids like blood using discrete sources of radiation |
-
1991
- 1991-12-20 EP EP92904266A patent/EP0516839B1/de not_active Expired - Lifetime
- 1991-12-20 AU AU91799/91A patent/AU648631B2/en not_active Ceased
- 1991-12-20 JP JP04504392A patent/JP3051998B2/ja not_active Expired - Lifetime
- 1991-12-20 CA CA002074830A patent/CA2074830C/en not_active Expired - Fee Related
- 1991-12-20 WO PCT/US1991/009710 patent/WO1992011059A1/en active IP Right Grant
- 1991-12-20 DE DE69131797T patent/DE69131797T2/de not_active Expired - Fee Related
-
1994
- 1994-08-11 US US08/289,175 patent/US5536238A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JP3051998B2 (ja) | 2000-06-12 |
US5536238A (en) | 1996-07-16 |
JPH05505133A (ja) | 1993-08-05 |
DE69131797D1 (de) | 1999-12-30 |
WO1992011059A1 (en) | 1992-07-09 |
CA2074830A1 (en) | 1992-06-21 |
EP0516839A4 (en) | 1993-09-15 |
CA2074830C (en) | 1999-03-02 |
AU9179991A (en) | 1992-07-22 |
EP0516839A1 (de) | 1992-12-09 |
EP0516839B1 (de) | 1999-11-24 |
AU648631B2 (en) | 1994-04-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |