DE69121885D1 - Durch körperliche aktivität gesteuerte vorrichtung zur iontophoretischen verabreichung von medikamenten - Google Patents

Durch körperliche aktivität gesteuerte vorrichtung zur iontophoretischen verabreichung von medikamenten

Info

Publication number
DE69121885D1
DE69121885D1 DE69121885T DE69121885T DE69121885D1 DE 69121885 D1 DE69121885 D1 DE 69121885D1 DE 69121885 T DE69121885 T DE 69121885T DE 69121885 T DE69121885 T DE 69121885T DE 69121885 D1 DE69121885 D1 DE 69121885D1
Authority
DE
Germany
Prior art keywords
physical activity
iontophoretic administration
drugs controlled
drugs
controlled
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69121885T
Other languages
English (en)
Other versions
DE69121885T2 (de
Inventor
Gary Lattin
Rama Padmanabhan
Michael Grace
Paul Sorenson
Joseph Phipps
Larry Mcnichols
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Priority claimed from PCT/US1991/002160 external-priority patent/WO1991015261A1/en
Publication of DE69121885D1 publication Critical patent/DE69121885D1/de
Application granted granted Critical
Publication of DE69121885T2 publication Critical patent/DE69121885T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0428Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432Anode and cathode
    • A61N1/044Shape of the electrode
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0428Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0448Drug reservoir
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/325Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
DE69121885T 1990-03-30 1991-03-29 Durch körperliche aktivität gesteuerte vorrichtung zur iontophoretischen verabreichung von medikamenten Expired - Lifetime DE69121885T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US50242290A 1990-03-30 1990-03-30
US07/671,267 US5213568A (en) 1990-03-30 1991-03-18 Activity controlled electrotransport drug delivery device
PCT/US1991/002160 WO1991015261A1 (en) 1990-03-30 1991-03-29 Activity controlled electrotransport drug delivery device

Publications (2)

Publication Number Publication Date
DE69121885D1 true DE69121885D1 (de) 1996-10-10
DE69121885T2 DE69121885T2 (de) 1997-03-20

Family

ID=27054150

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69121885T Expired - Lifetime DE69121885T2 (de) 1990-03-30 1991-03-29 Durch körperliche aktivität gesteuerte vorrichtung zur iontophoretischen verabreichung von medikamenten

Country Status (8)

Country Link
US (1) US5213568A (de)
EP (1) EP0522062B1 (de)
JP (1) JP3300953B2 (de)
AT (1) ATE142116T1 (de)
AU (1) AU649439B2 (de)
CA (1) CA2079007C (de)
DE (1) DE69121885T2 (de)
FI (1) FI111131B (de)

Families Citing this family (103)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5499967A (en) * 1992-02-27 1996-03-19 Societe Anonyme Dite: Laboratoires D'hygiene Societe Anonyme Dite: Et De Dietetique (L.H.D.) Transdermal drug delivery device with waveshape generator
US5427585A (en) * 1993-03-29 1995-06-27 Bettinger; David S. On-demand iontophoretic system
US5508030A (en) * 1993-08-05 1996-04-16 Bierman; Howard R. Creating new capillary blood pools for practicing bidirectional medicine
US5635204A (en) * 1994-03-04 1997-06-03 Montefiore Medical Center Method for transdermal induction of anesthesia, analgesia or sedation
US7027859B1 (en) 1994-09-26 2006-04-11 Alza Corporation Electrotransport delivery device having improved safety and reduced abuse potential
IE960312A1 (en) * 1995-06-02 1996-12-11 Alza Corp An electrotransport delivery device with voltage boosting¹circuit
SE9601528D0 (sv) 1996-04-23 1996-04-23 Pharmacia Ab Transdermally administered dextromethorphan as antitissue agent
US6047208A (en) * 1997-08-27 2000-04-04 Becton, Dickinson And Company Iontophoretic controller
ATE373957T1 (de) 1997-10-09 2007-10-15 Univ Emory Verfahren und vorrichtung zur transdermalen verabreichung von lithium
JP2002508228A (ja) 1997-12-16 2002-03-19 アルザ・コーポレーション 調整された投与を維持する人為的負荷を備えた調整器
ES2281940T3 (es) 1997-12-17 2007-10-01 Alza Corporation Iontoforesis con ajuste programado de la corriente electrica.
US6200264B1 (en) 1998-08-06 2001-03-13 Medtronic Inc. Ambulatory recorder having wireless data transfer with a multi-plane lens
US6141574A (en) * 1998-08-06 2000-10-31 Medtronic, Inc. Ambulatory recorder having sliding period switches
US6128520A (en) * 1998-08-06 2000-10-03 Medtronic, Inc. Ambulatory recorder having volatile and non-volatile memories
US6154668A (en) * 1998-08-06 2000-11-28 Medtronics Inc. Ambulatory recorder having a real time and non-real time processors
US6142938A (en) * 1998-08-06 2000-11-07 Medtronic Inc. Ambulatory data recorder having ergonomically shaped housing
US6077223A (en) * 1998-08-06 2000-06-20 Medtronic, Inc. Ambulatory recorder having control screen to present dual interface for dual users
US6014578A (en) * 1998-08-06 2000-01-11 Meotronic, Inc. Ambulatory recorder having method of configuring size of data subject to loss in volatile memory
US6115622A (en) * 1998-08-06 2000-09-05 Medtronic, Inc. Ambulatory recorder having enhanced sampling technique
US6119029A (en) * 1998-08-06 2000-09-12 Medtronic, Inc. Ambulatory recorder having splash resistant sensor ports
EP1109594B1 (de) 1998-08-31 2004-10-27 Johnson & Johnson Consumer Companies, Inc. Elektrotransportvorrichtung mit klingen
US6245013B1 (en) 1998-12-14 2001-06-12 Medtronic, Inc. Ambulatory recorder having synchronized communication between two processors
WO2000062857A1 (en) * 1999-04-16 2000-10-26 Johnson & Johnson Consumer Companies, Inc. Electrotransport delivery system comprising internal sensors
US6516749B1 (en) * 1999-06-18 2003-02-11 Salasoft, Inc. Apparatus for the delivery to an animal of a beneficial agent
US6890553B1 (en) 1999-07-08 2005-05-10 Johnson & Johnson Consumer Companies, Inc. Exothermic topical delivery device
AU6076200A (en) 1999-07-08 2001-01-30 Johnson & Johnson Consumer Companies, Inc. Exothermic bandage
US7113821B1 (en) 1999-08-25 2006-09-26 Johnson & Johnson Consumer Companies, Inc. Tissue electroperforation for enhanced drug delivery
US7133717B2 (en) * 1999-08-25 2006-11-07 Johnson & Johnson Consumer Companies, Inc. Tissue electroperforation for enhanced drug delivery and diagnostic sampling
US6512950B2 (en) 2000-02-18 2003-01-28 University Of Utah Research Foundation Methods for delivering agents using alternating current
AU2001241483A1 (en) 2000-02-18 2001-08-27 University Of Utah Research Foundation Methods for extracting substances using alternating current
US7404815B2 (en) * 2000-05-01 2008-07-29 Lifescan, Inc. Tissue ablation by shear force for sampling biological fluids and delivering active agents
US7137975B2 (en) * 2001-02-13 2006-11-21 Aciont, Inc. Method for increasing the battery life of an alternating current iontophoresis device using a barrier-modifying agent
AU2002363106B2 (en) * 2001-10-24 2008-04-24 Power Paper Ltd. Device and method for controlled delivery of active substance into the skin
US6638241B2 (en) * 2002-01-03 2003-10-28 Israel Yerushalmy Apparatus for treating bruxism
US10173008B2 (en) 2002-01-29 2019-01-08 Baxter International Inc. System and method for communicating with a dialysis machine through a network
US8775196B2 (en) 2002-01-29 2014-07-08 Baxter International Inc. System and method for notification and escalation of medical data
US8234128B2 (en) 2002-04-30 2012-07-31 Baxter International, Inc. System and method for verifying medical device operational parameters
US7596407B2 (en) 2004-03-26 2009-09-29 Solvay Pharmaceuticals, B.V. Transdermal iontophoretic delivery of piperazinyl-2(3H)-benzoxazolone compounds
EP1595542A1 (de) * 2004-03-26 2005-11-16 Solvay Pharmaceuticals B.V. Transdermale iontophoretische Verabreichung von Piperazinyl-2(3H)-benzoxazolon-Verbindungen
US7519409B2 (en) * 2005-12-29 2009-04-14 Medtronic, Inc. Implantable cell/tissue-based biosensing device
EP1998829B1 (de) 2006-03-14 2011-02-09 University Of Southern California Mems-Vorrichtung zur Wirkstofffreisetzung
JP5241714B2 (ja) 2006-07-07 2013-07-17 プロテウス デジタル ヘルス, インコーポレイテッド スマートな非経口送達システム
US8622991B2 (en) * 2007-03-19 2014-01-07 Insuline Medical Ltd. Method and device for drug delivery
WO2009081262A1 (en) 2007-12-18 2009-07-02 Insuline Medical Ltd. Drug delivery device with sensor for closed-loop operation
US9220837B2 (en) 2007-03-19 2015-12-29 Insuline Medical Ltd. Method and device for drug delivery
MX2009010000A (es) 2007-03-19 2010-03-17 Insuline Medical Ltd Dispositivo para el suministro de farmaco.
US9125979B2 (en) 2007-10-25 2015-09-08 Proteus Digital Health, Inc. Fluid transfer port information system
WO2009067463A1 (en) 2007-11-19 2009-05-28 Proteus Biomedical, Inc. Body-associated fluid transport structure evaluation devices
EP2666510B1 (de) 2007-12-20 2017-10-18 University Of Southern California Vorrichtung zur kontrollierten Abgabe von Therapeutika
US8862223B2 (en) * 2008-01-18 2014-10-14 Activatek, Inc. Active transdermal medicament patch and circuit board for same
US20110160640A1 (en) * 2008-01-18 2011-06-30 Yanaki Jamal S Operation management of active transdermal medicament patch
US8337404B2 (en) 2010-10-01 2012-12-25 Flint Hills Scientific, Llc Detecting, quantifying, and/or classifying seizures using multimodal data
US8382667B2 (en) 2010-10-01 2013-02-26 Flint Hills Scientific, Llc Detecting, quantifying, and/or classifying seizures using multimodal data
US8571643B2 (en) 2010-09-16 2013-10-29 Flint Hills Scientific, Llc Detecting or validating a detection of a state change from a template of heart rate derivative shape or heart beat wave complex
US9333297B2 (en) 2008-05-08 2016-05-10 Minipumps, Llc Drug-delivery pump with intelligent control
US8231609B2 (en) 2008-05-08 2012-07-31 Minipumps, Llc Drug-delivery pumps and methods of manufacture
CN104353150A (zh) 2008-05-08 2015-02-18 迷你泵有限责任公司 可植入泵和用于可植入泵的插管
US8057679B2 (en) 2008-07-09 2011-11-15 Baxter International Inc. Dialysis system having trending and alert generation
US10089443B2 (en) 2012-05-15 2018-10-02 Baxter International Inc. Home medical device systems and methods for therapy prescription and tracking, servicing and inventory
US8554579B2 (en) 2008-10-13 2013-10-08 Fht, Inc. Management, reporting and benchmarking of medication preparation
BRPI0916125A2 (pt) 2008-11-07 2015-11-03 Insuline Medical Ltd "dispositivo de tratamento"
US9041541B2 (en) 2010-01-28 2015-05-26 Seventh Sense Biosystems, Inc. Monitoring or feedback systems and methods
US20120277629A1 (en) 2011-04-29 2012-11-01 Seventh Sense Biosystems, Inc. Systems and methods for collection and/or manipulation of blood spots or other bodily fluids
EP2408372B1 (de) 2009-03-02 2019-01-09 Seventh Sense Biosystems, Inc. Vorrichtungen im zusammenhang mit der entnahme von blutproben
US20110105951A1 (en) * 2009-10-30 2011-05-05 Seventh Sense Biosystems, Inc. Systems and methods for treating, sanitizing, and/or shielding the skin or devices applied to the skin
US20110105952A1 (en) * 2009-10-30 2011-05-05 Seventh Sense Biosystems, Inc. Relatively small devices applied to the skin, modular systems, and methods of use thereof
US9295417B2 (en) 2011-04-29 2016-03-29 Seventh Sense Biosystems, Inc. Systems and methods for collecting fluid from a subject
WO2012018486A2 (en) 2010-07-26 2012-02-09 Seventh Sense Biosystems, Inc. Rapid delivery and/or receiving of fluids
US9033898B2 (en) 2010-06-23 2015-05-19 Seventh Sense Biosystems, Inc. Sampling devices and methods involving relatively little pain
EP2467797B1 (de) 2009-08-18 2017-07-19 MiniPumps, LLC Elektrolytische arzneimittelverabreichungspumpe mit adaptiver steuerung
US20110060280A1 (en) * 2009-09-04 2011-03-10 Sean Caffey Adhesive skin patch with pump for subcutaneous drug delivery
CN102905612A (zh) 2010-02-01 2013-01-30 普罗秋斯数字健康公司 双腕式数据采集系统
JP5841951B2 (ja) 2010-02-01 2016-01-13 プロテウス デジタル ヘルス, インコーポレイテッド データ収集システム
US8562536B2 (en) 2010-04-29 2013-10-22 Flint Hills Scientific, Llc Algorithm for detecting a seizure from cardiac data
US8649871B2 (en) 2010-04-29 2014-02-11 Cyberonics, Inc. Validity test adaptive constraint modification for cardiac data used for detection of state changes
US8831732B2 (en) 2010-04-29 2014-09-09 Cyberonics, Inc. Method, apparatus and system for validating and quantifying cardiac beat data quality
US20120016308A1 (en) 2010-07-16 2012-01-19 Seventh Sense Biosystems, Inc. Low-pressure packaging for fluid devices
US8641646B2 (en) 2010-07-30 2014-02-04 Cyberonics, Inc. Seizure detection using coordinate data
US20120039809A1 (en) 2010-08-13 2012-02-16 Seventh Sense Biosystems, Inc. Systems and techniques for monitoring subjects
US8684921B2 (en) 2010-10-01 2014-04-01 Flint Hills Scientific Llc Detecting, assessing and managing epilepsy using a multi-variate, metric-based classification analysis
WO2012064802A1 (en) 2010-11-09 2012-05-18 Seventh Sense Biosystems, Inc. Systems and interfaces for blood sampling
US8827930B2 (en) * 2011-01-10 2014-09-09 Bioguidance Llc System and method for patient monitoring
US9504390B2 (en) 2011-03-04 2016-11-29 Globalfoundries Inc. Detecting, assessing and managing a risk of death in epilepsy
US8428709B1 (en) * 2012-06-11 2013-04-23 Incline Therapeutics, Inc. Current control for electrotransport drug delivery
US8428708B1 (en) 2012-05-21 2013-04-23 Incline Therapeutics, Inc. Self-test for analgesic product
US8725239B2 (en) 2011-04-25 2014-05-13 Cyberonics, Inc. Identifying seizures using heart rate decrease
US9402550B2 (en) 2011-04-29 2016-08-02 Cybertronics, Inc. Dynamic heart rate threshold for neurological event detection
US20130158468A1 (en) 2011-12-19 2013-06-20 Seventh Sense Biosystems, Inc. Delivering and/or receiving material with respect to a subject surface
ES2597081T3 (es) 2011-04-29 2017-01-13 Seventh Sense Biosystems, Inc. Entrega y/o recepción de fluidos
US9681836B2 (en) 2012-04-23 2017-06-20 Cyberonics, Inc. Methods, systems and apparatuses for detecting seizure and non-seizure states
US10448839B2 (en) 2012-04-23 2019-10-22 Livanova Usa, Inc. Methods, systems and apparatuses for detecting increased risk of sudden death
KR20150048816A (ko) 2012-08-31 2015-05-07 백스터 코포레이션 잉글우드 약제 요청서 집행 시스템 및 방법
KR101974258B1 (ko) 2012-10-26 2019-04-30 백스터 코포레이션 잉글우드 의료 투여분 조제 시스템을 위한 개선된 이미지 취득
US9375079B2 (en) 2012-10-26 2016-06-28 Baxter Corporation Englewood Work station for medical dose preparation system
US10220211B2 (en) 2013-01-22 2019-03-05 Livanova Usa, Inc. Methods and systems to diagnose depression
KR20160009541A (ko) * 2013-03-15 2016-01-26 프로메데온 파마, 엘엘씨 화합물의 경피전달 장치, 시스템, 및 방법
JP2017525032A (ja) 2014-06-30 2017-08-31 バクスター・コーポレーション・イングルウッドBaxter Corporation Englewood 管理された医療情報交換
US11107574B2 (en) 2014-09-30 2021-08-31 Baxter Corporation Englewood Management of medication preparation with formulary management
US11575673B2 (en) 2014-09-30 2023-02-07 Baxter Corporation Englewood Central user management in a distributed healthcare information management system
WO2016090091A1 (en) 2014-12-05 2016-06-09 Baxter Corporation Englewood Dose preparation data analytics
SG11201707114XA (en) 2015-03-03 2017-09-28 Baxter Corp Englewood Pharmacy workflow management with integrated alerts
WO2016207206A1 (en) 2015-06-25 2016-12-29 Gambro Lundia Ab Medical device system and method having a distributed database
KR102476516B1 (ko) 2016-12-21 2022-12-09 감브로 룬디아 아베 외부 도메인을 지원하는 안전한 클러스터 도메인을 구비한 정보 기술 인프라를 포함하는 의료 장치 시스템

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3618601A (en) * 1969-10-16 1971-11-09 Thatcher W Richardson Iontophoresis unit
US4146029A (en) * 1974-04-23 1979-03-27 Ellinwood Jr Everett H Self-powered implanted programmable medication system and method
GB1553289A (en) * 1975-05-23 1979-09-26 Bacchelli S Instrument for measuring body resistance
US4141359A (en) * 1976-08-16 1979-02-27 University Of Utah Epidermal iontophoresis device
US4292968A (en) * 1979-11-26 1981-10-06 Sybron Corporation Electric supply for ion therapy
US4406658A (en) * 1981-03-06 1983-09-27 Medtronic, Inc. Iontophoretic device with reversible polarity
US4428378A (en) * 1981-11-19 1984-01-31 Medtronic, Inc. Rate adaptive pacer
US4704119A (en) * 1983-02-03 1987-11-03 Alza Corporation Method comprising transdermal and buccal treatment of angina
US4639244A (en) * 1983-05-03 1987-01-27 Nabil I. Rizk Implantable electrophoretic pump for ionic drugs and associated methods
US4808152A (en) * 1983-08-18 1989-02-28 Drug Delivery Systems Inc. System and method for controlling rate of electrokinetic delivery of a drug
FR2562800A1 (fr) * 1984-04-11 1985-10-18 Fournier Laboratoires Dispositif pour l'administration percutanee de medicaments
US4702732A (en) * 1984-12-24 1987-10-27 Trustees Of Boston University Electrodes, electrode assemblies, methods, and systems for tissue stimulation and transdermal delivery of pharmacologically active ligands
US4860751A (en) * 1985-02-04 1989-08-29 Cordis Corporation Activity sensor for pacemaker control
ATE80048T1 (de) * 1985-06-10 1992-09-15 Drug Delivery Systems Inc Programmierbare kontrolle und bausystem eines verabreichungsgeraetes fuer transdermische arzneien.
US4886489A (en) * 1986-03-19 1989-12-12 Jacobsen Stephen C Flow-through methods and apparatus for iontophoresis application of medicaments at a controlled pH
US4725263A (en) * 1986-07-31 1988-02-16 Medtronic, Inc. Programmable constant current source transdermal drug delivery system
US4822334A (en) * 1986-12-04 1989-04-18 Robert Tapper Electrical dosimetry control system
WO1988008729A1 (en) * 1987-05-15 1988-11-17 Newman Martin H Iontophoresis drug delivery system
AU615188B2 (en) * 1987-05-28 1991-09-26 Drug Delivery Systems Inc. Pulsating transdermal drug delivery system
JPS6456060A (en) * 1987-08-27 1989-03-02 Hayashibara Takeshi Low frequency medical treatment device
US4942883A (en) * 1987-09-29 1990-07-24 Newman Martin H Drug delivery device

Also Published As

Publication number Publication date
AU649439B2 (en) 1994-05-26
CA2079007A1 (en) 1991-10-01
CA2079007C (en) 2001-08-07
FI924376A0 (fi) 1992-09-29
FI111131B (fi) 2003-06-13
EP0522062B1 (de) 1996-09-04
DE69121885T2 (de) 1997-03-20
US5213568A (en) 1993-05-25
JP3300953B2 (ja) 2002-07-08
FI924376A (fi) 1992-09-29
AU7586891A (en) 1991-10-30
ATE142116T1 (de) 1996-09-15
JPH05508558A (ja) 1993-12-02
EP0522062A1 (de) 1993-01-13

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