DE69114006D1 - Zusammensetzungen und verfahren für die kontrollierte freisetzung von löslichen wirkstoffen. - Google Patents

Zusammensetzungen und verfahren für die kontrollierte freisetzung von löslichen wirkstoffen.

Info

Publication number
DE69114006D1
DE69114006D1 DE69114006T DE69114006T DE69114006D1 DE 69114006 D1 DE69114006 D1 DE 69114006D1 DE 69114006 T DE69114006 T DE 69114006T DE 69114006 T DE69114006 T DE 69114006T DE 69114006 D1 DE69114006 D1 DE 69114006D1
Authority
DE
Germany
Prior art keywords
compositions
methods
controlled release
active substances
soluble active
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69114006T
Other languages
English (en)
Other versions
DE69114006T2 (de
Inventor
Robert Eury
Rajesh Patel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Heron Therapeutics LLC
Original Assignee
Advanced Polymer Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Advanced Polymer Systems Inc filed Critical Advanced Polymer Systems Inc
Publication of DE69114006D1 publication Critical patent/DE69114006D1/de
Application granted granted Critical
Publication of DE69114006T2 publication Critical patent/DE69114006T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
DE69114006T 1990-06-20 1991-06-17 Zusammensetzungen und verfahren für die kontrollierte freisetzung von löslichen wirkstoffen. Expired - Fee Related DE69114006T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54111190A 1990-06-20 1990-06-20
PCT/US1991/004313 WO1991019483A1 (en) 1990-06-20 1991-06-17 Compositions and methods for the controlled release of soluble active substances

Publications (2)

Publication Number Publication Date
DE69114006D1 true DE69114006D1 (de) 1995-11-23
DE69114006T2 DE69114006T2 (de) 1996-05-02

Family

ID=24158219

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69114006T Expired - Fee Related DE69114006T2 (de) 1990-06-20 1991-06-17 Zusammensetzungen und verfahren für die kontrollierte freisetzung von löslichen wirkstoffen.

Country Status (7)

Country Link
US (1) US5316774A (de)
EP (1) EP0533799B1 (de)
JP (1) JP3286315B2 (de)
AU (1) AU8050791A (de)
DE (1) DE69114006T2 (de)
HK (1) HK1007108A1 (de)
WO (1) WO1991019483A1 (de)

Families Citing this family (78)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5874091A (en) * 1990-09-27 1999-02-23 L'oreal Cosmetic composition comprising a dispersion of lipid vesicles as well as melanin pigments
US5981719A (en) 1993-03-09 1999-11-09 Epic Therapeutics, Inc. Macromolecular microparticles and methods of production and use
US6090925A (en) 1993-03-09 2000-07-18 Epic Therapeutics, Inc. Macromolecular microparticles and methods of production and use
FR2717388B1 (fr) * 1994-03-21 1996-11-22 Synthelabo Formes galéniques à libération prolongée du chlorhydrate d'alfuzosine.
AT403988B (de) * 1994-05-18 1998-07-27 Lannacher Heilmittel Festes orales retardpräparat
US5583162A (en) * 1994-06-06 1996-12-10 Biopore Corporation Polymeric microbeads and method of preparation
US5849327A (en) * 1994-07-29 1998-12-15 Advanced Polymer Systems, Inc. Delivery of drugs to the lower gastrointestinal tract
GB2292079B (en) * 1994-08-12 1998-07-15 Flexpharm Ltd Coated prednisolone preparation for the treatment of inflamatory bowel disease
US5830967A (en) * 1994-10-24 1998-11-03 Amcol International Corporation Process for producing an oil and water adsorbent polymer capable of entrapping solid particles and liquids and the product thereof
US6107429A (en) * 1994-10-24 2000-08-22 Amcol International Corporation Process for producing an oil and water adsorbent polymer capable of entrapping solid particles and liquids and the product thereof
US5837790A (en) * 1994-10-24 1998-11-17 Amcol International Corporation Precipitation polymerization process for producing an oil adsorbent polymer capable of entrapping solid particles and liquids and the product thereof
US5712358A (en) * 1995-06-07 1998-01-27 Amcol International Corporation Process for producing an oil sorbent copolymer and the product thereof
ATE206043T1 (de) * 1996-01-16 2001-10-15 Advanced Polymer Systems Inc Örtliche arzneistoffabgabe in tieferen magendarmtraktabschnitten
US5773031A (en) * 1996-02-27 1998-06-30 L. Perrigo Company Acetaminophen sustained-release formulation
SE9604124D0 (sv) 1996-11-12 1996-11-12 Pharmacia & Upjohn Ab Compact member, method of manufacturing and use thereof
JP2001503766A (ja) * 1996-11-12 2001-03-21 フアーマシア・アンド・アツプジヨン・アー・ベー 複数の多孔質セルロースマトリクス（ｐｃｍ）を含むコンパクト部材、その製造および使用方法
US6048908A (en) * 1997-06-27 2000-04-11 Biopore Corporation Hydrophilic polymeric material
US6585933B1 (en) 1999-05-03 2003-07-01 Betzdearborn, Inc. Method and composition for inhibiting corrosion in aqueous systems
US6918765B1 (en) 1999-01-25 2005-07-19 Dentsply Research & Development Corp. Hydrogel dental adhesive composition, product, system, method and dispenser
MXPA01007463A (es) 1999-01-29 2002-06-04 Losan Pharma Gmbh Composiciones farmaceuticas.
US20020004502A1 (en) * 2000-01-05 2002-01-10 Redmond H. Paul Treatment of inflammatory bowel disease
US6491953B1 (en) * 2000-01-07 2002-12-10 Amcol International Corporation Controlled release compositions and method
US6465425B1 (en) 2000-02-10 2002-10-15 Alkermes Controlled Therapeutics, Inc. Microencapsulation and sustained release of biologically active acid-stable or free sulfhydryl-containing proteins
MXPA03001406A (es) 2000-08-15 2004-05-04 Surmodics Inc Matriz de incorporacion de medicamento.
US20030152630A1 (en) * 2001-05-11 2003-08-14 Ng Steven Y. PEG-POE, PEG-POE-PEG, and POE-PEG-POE block copolymers
US6590059B2 (en) * 2001-05-11 2003-07-08 Ap Pharma, Inc. Bioerodible polyorthoesters from dioxolane-based diketene acetals
US20050244498A1 (en) * 2001-09-14 2005-11-03 Biovail Laboratories, Inc. Modified-release compositions of at least one form of venlafaxine
US6524606B1 (en) * 2001-11-16 2003-02-25 Ap Pharma, Inc. Bioerodible polyorthoesters containing amine groups
AU2002352988A1 (en) * 2001-11-30 2003-06-17 Bristol-Myers Squibb Company Pipette configurations and arrays thereof for measuring cellular electrical properties
CA2822457C (en) 2001-12-14 2016-03-08 The University Of Wyoming Methods and compositions for controlled resease of drugs
US8133501B2 (en) 2002-02-08 2012-03-13 Boston Scientific Scimed, Inc. Implantable or insertable medical devices for controlled drug delivery
US8685427B2 (en) * 2002-07-31 2014-04-01 Boston Scientific Scimed, Inc. Controlled drug delivery
US7094369B2 (en) * 2002-03-29 2006-08-22 Scimed Life Systems, Inc. Processes for manufacturing polymeric microspheres
US7462366B2 (en) 2002-03-29 2008-12-09 Boston Scientific Scimed, Inc. Drug delivery particle
US7098252B2 (en) * 2002-04-01 2006-08-29 Rohm And Haas Company Preparation of macroreticular polymers
WO2003105917A2 (en) 2002-06-12 2003-12-24 Scimed Life Systems, Inc. Bulking agents
US8920826B2 (en) * 2002-07-31 2014-12-30 Boston Scientific Scimed, Inc. Medical imaging reference devices
US7842377B2 (en) 2003-08-08 2010-11-30 Boston Scientific Scimed, Inc. Porous polymeric particle comprising polyvinyl alcohol and having interior to surface porosity-gradient
US8012454B2 (en) * 2002-08-30 2011-09-06 Boston Scientific Scimed, Inc. Embolization
US20040062778A1 (en) * 2002-09-26 2004-04-01 Adi Shefer Surface dissolution and/or bulk erosion controlled release compositions and devices
WO2004037305A1 (en) 2002-10-21 2004-05-06 Allegiance Corporation Coating composition for skin-contacting surface of elastomeric articles and articles containing the same
US7883490B2 (en) 2002-10-23 2011-02-08 Boston Scientific Scimed, Inc. Mixing and delivery of therapeutic compositions
US7670627B2 (en) * 2002-12-09 2010-03-02 Salvona Ip Llc pH triggered targeted controlled release systems for the delivery of pharmaceutical active ingredients
JP4170106B2 (ja) * 2003-02-04 2008-10-22 花王株式会社 多孔性粒子及び化粧料
US7976823B2 (en) * 2003-08-29 2011-07-12 Boston Scientific Scimed, Inc. Ferromagnetic particles and methods
US7901770B2 (en) * 2003-11-04 2011-03-08 Boston Scientific Scimed, Inc. Embolic compositions
CA2556753C (en) * 2004-02-20 2014-11-25 Lifescape Biosciences Incorporated Compositions and methods for sleep regulation
US20050208134A1 (en) * 2004-02-25 2005-09-22 Shlomo Magdassi Biocompatible polymeric beads and use thereof
US7736671B2 (en) * 2004-03-02 2010-06-15 Boston Scientific Scimed, Inc. Embolization
US20040224019A1 (en) * 2004-03-03 2004-11-11 Adi Shefer Oral controlled release system for targeted drug delivery into the cell and its nucleus for gene therapy, DNA vaccination, and administration of gene based drugs
US8173176B2 (en) 2004-03-30 2012-05-08 Boston Scientific Scimed, Inc. Embolization
US20050265955A1 (en) * 2004-05-28 2005-12-01 Mallinckrodt Inc. Sustained release preparations
US7311861B2 (en) * 2004-06-01 2007-12-25 Boston Scientific Scimed, Inc. Embolization
US8425550B2 (en) * 2004-12-01 2013-04-23 Boston Scientific Scimed, Inc. Embolic coils
WO2006065991A2 (en) * 2004-12-17 2006-06-22 Dr. Reddy's Laboratories Ltd. Dispersion for delivering active agents
US7727555B2 (en) 2005-03-02 2010-06-01 Boston Scientific Scimed, Inc. Particles
US7858183B2 (en) 2005-03-02 2010-12-28 Boston Scientific Scimed, Inc. Particles
US7963287B2 (en) 2005-04-28 2011-06-21 Boston Scientific Scimed, Inc. Tissue-treatment methods
US8053000B2 (en) 2005-06-07 2011-11-08 Dr. Reddy's Laboratories Limited Compositions for drug delivery
US9463426B2 (en) 2005-06-24 2016-10-11 Boston Scientific Scimed, Inc. Methods and systems for coating particles
WO2007011972A2 (en) * 2005-07-19 2007-01-25 Inverseon, Inc. Improved pharmacokinetic profile of beta-adrenergic inverse agonists for the treatment of pulmonary airway diseases
US8007509B2 (en) 2005-10-12 2011-08-30 Boston Scientific Scimed, Inc. Coil assemblies, components and methods
US8152839B2 (en) 2005-12-19 2012-04-10 Boston Scientific Scimed, Inc. Embolic coils
US8101197B2 (en) 2005-12-19 2012-01-24 Stryker Corporation Forming coils
US7947368B2 (en) 2005-12-21 2011-05-24 Boston Scientific Scimed, Inc. Block copolymer particles
US20080020023A1 (en) * 2006-07-20 2008-01-24 Shiping Wang Nonaqueous coating composition for elastomeric articles and articles containing the same
US8414927B2 (en) 2006-11-03 2013-04-09 Boston Scientific Scimed, Inc. Cross-linked polymer particles
US20110223297A1 (en) * 2010-03-12 2011-09-15 Pepsico., Inc. Anti-Caking Agent for Flavored Products
US20140348936A1 (en) * 2011-12-16 2014-11-27 Celanese Eva Performance Polymers, Inc. Gastroretentive controlled release vehicles that include ethylene copolymers, ethyl celluloses, and/or thermoplastic polyurethanes
KR102246242B1 (ko) * 2013-05-17 2021-04-28 쓰리엠 이노베이티브 프로퍼티즈 컴파니 중합체 복합 입자로부터의 생물 활성제의 방출
US9422411B2 (en) 2013-05-17 2016-08-23 3M Innovative Properties Company Reaction mixture, porous particles and methods of making
WO2015092602A1 (en) 2013-12-17 2015-06-25 Ranbaxy Laboratories Limited Topical pharmaceutical composition of a retinoid
WO2016053830A1 (en) 2014-10-01 2016-04-07 3M Innovative Properties Company Articles including fibrous substrates and porous polymeric particles and methods of making same
CA2936740C (en) 2014-10-31 2017-10-10 Purdue Pharma Methods and compositions particularly for treatment of attention deficit disorder
EP3426290A1 (de) * 2016-03-07 2019-01-16 GlaxoSmithKline Biologicals SA Wirkstofffreisetzungspartikel
EP3448923B1 (de) * 2016-04-25 2021-03-17 3M Innovative Properties Company Kompositpartikel zur härtung von epoxidharzzusammensetzungen und unter verwendung der partikel hergestellte härtbare und gehärtete epoxidharzzusammensetzungen
CN111315381A (zh) * 2017-11-02 2020-06-19 石原产业株式会社 缓释性医药组合物
US10722473B2 (en) 2018-11-19 2020-07-28 Purdue Pharma L.P. Methods and compositions particularly for treatment of attention deficit disorder

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4221871A (en) * 1970-12-16 1980-09-09 Rohm And Haas Company Reticular crosslinked monovinylidene N-heterocyclic copolymer
US3991017A (en) * 1973-12-20 1976-11-09 Rohm And Haas Company Ion exchange resins derived from hybrid copolymers
DE2908794C2 (de) * 1978-03-09 1984-09-13 Japan Atomic Energy Research Institute, Tokio/Tokyo Verfahren zur Herstellung eines eine physiologisch aktive Substanz enthaltenden Polymerpräparates
CA1236023A (en) * 1984-07-18 1988-05-03 Yegnaswami Raghunathan Controlled release pharmaceutical preparations
US4772475A (en) * 1985-03-08 1988-09-20 Yamanouchi Pharmaceutical Co., Ltd. Controlled-release multiple units pharmaceutical formulation
US4692462A (en) * 1985-03-18 1987-09-08 Menley & James Laboratories, Ltd. Compositions and method of controlling transdermal penetration of topical and systemic agents
US4575539A (en) * 1985-06-03 1986-03-11 E. R. Squibb & Sons, Inc. Drug delivery systems including novel interpenetrating polymer networks and method
US4690825A (en) * 1985-10-04 1987-09-01 Advanced Polymer Systems, Inc. Method for delivering an active ingredient by controlled time release utilizing a novel delivery vehicle which can be prepared by a process utilizing the active ingredient as a porogen
US4788055A (en) * 1985-12-09 1988-11-29 Ciba-Geigy Corporation Resinate sustained release dextromethorphan composition
US4940556A (en) * 1986-01-30 1990-07-10 Syntex (U.S.A.) Inc. Method of preparing long acting formulation
ZA886284B (en) * 1987-08-31 1990-04-25 Advanced Polymer Systems Inc Controlled release formulations
US4806360A (en) * 1987-10-23 1989-02-21 Advanced Polymer Systems Synthetic melanin aggregates
US4963369A (en) * 1989-01-19 1990-10-16 Wm. Wrigley Jr. Co. Gum composition containing dispersed porous beads containing active chewing gum ingredients and method

Also Published As

Publication number Publication date
WO1991019483A1 (en) 1991-12-26
EP0533799A4 (en) 1993-04-28
JP3286315B2 (ja) 2002-05-27
US5316774A (en) 1994-05-31
AU8050791A (en) 1992-01-07
DE69114006T2 (de) 1996-05-02
EP0533799A1 (de) 1993-03-31
EP0533799B1 (de) 1995-10-18
HK1007108A1 (en) 1999-04-01
JPH05507494A (ja) 1993-10-28

Similar Documents

Publication Publication Date Title
DE69114006D1 (de) Zusammensetzungen und verfahren für die kontrollierte freisetzung von löslichen wirkstoffen.
DE68918142T2 (de) Zusammensetzungen und Verfahren zur kontrollierten Freisetzung von Duftstoffen.
ATE112963T1 (de) Gewebeentzusammensetzung und verfahren.
DE69011220D1 (de) Kraftfahrzeug-Überzugsmassen und Verfahren.
DE59001092D1 (de) Polypropylenwachs und verfahren zu seiner herstellung.
DE3851913T2 (de) Superabsorbierende Zusammensetzung und Verfahren.
DE68909712D1 (de) Biomedizinisches Material und Verfahren zu seiner Herstellung.
DE3880515D1 (de) Granuliertes mittel fuer wiederkaeuer und verfahren zu dessen herstellung.
DE68905448T2 (de) Siliziumpulver und Verfahren zu seiner Herstellung.
DE69013581D1 (de) Verfahren und einrichtung für die ununterbrochene herstellung absorbierender körper.
DE3883326D1 (de) Poroeser film, verfahren zu seiner herstellung und absorbierende sanitaere gegenstaende.
DE3786891T2 (de) Sehr weicher Spinnvliesstoff und Verfahren zur Herstellung desselben.
DE3882461D1 (de) Retroreflektierendes ueberzugsmittel und zusammensetzung zu seiner herstellung.
DE3775294D1 (de) Implantatwerkstoff und verfahren zu seiner herstellung.
DE69017348T2 (de) Thyristor und Verfahren zu dessen Herstellung.
DE69022926D1 (de) Virtuelle Mikrophonanlage und dafür bestimmtes Verfahren.
DE3887128D1 (de) Konservierungsmaterial und Verfahren zu seiner Herstellung.
DE58903737D1 (de) Flaechenlager und verfahren zu seiner herstellung.
DE3874732D1 (de) Weisses deodorierungsmittel und verfahren zu seiner herstellung.
DE69108766T2 (de) Aerosol Mischungsvorrichtung und Verfahren.
ATE85184T1 (de) Pestizide zusammensetzungen und verfahren.
NL7904856A (nl) Staal en werkwijze voor de bereiding van staal.
DE3775012D1 (de) Oberflaechenaktives mittel und verfahren zur dessen herstellung.
DE3774542D1 (de) Halbleiterlaser und verfahren zu seiner herstellung.
DE69016882D1 (de) Entwickler und Verfahren zu seiner Herstellung.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee