DE69105106D1 - Im wasser schnell suspendierbare pharmazeutische zusammensetzung. - Google Patents

Im wasser schnell suspendierbare pharmazeutische zusammensetzung.

Info

Publication number
DE69105106D1
DE69105106D1 DE69105106T DE69105106T DE69105106D1 DE 69105106 D1 DE69105106 D1 DE 69105106D1 DE 69105106 T DE69105106 T DE 69105106T DE 69105106 T DE69105106 T DE 69105106T DE 69105106 D1 DE69105106 D1 DE 69105106D1
Authority
DE
Germany
Prior art keywords
pct
drug
pharmaceutical composition
water
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69105106T
Other languages
English (en)
Other versions
DE69105106T2 (de
Inventor
Marco Zema
Luigi Mapelli
Marco Marconi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Adare Pharmaceuticals SRL
Original Assignee
Eurand International SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eurand International SpA filed Critical Eurand International SpA
Publication of DE69105106D1 publication Critical patent/DE69105106D1/de
Application granted granted Critical
Publication of DE69105106T2 publication Critical patent/DE69105106T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F02—COMBUSTION ENGINES; HOT-GAS OR COMBUSTION-PRODUCT ENGINE PLANTS
    • F02B—INTERNAL-COMBUSTION PISTON ENGINES; COMBUSTION ENGINES IN GENERAL
    • F02B2275/00—Other engines, components or details, not provided for in other groups of this subclass
    • F02B2275/14—Direct injection into combustion chamber

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Plant Substances (AREA)
DE69105106T 1990-07-11 1991-07-04 Im wasser schnell suspendierbare pharmazeutische zusammensetzung. Expired - Fee Related DE69105106T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT02090890A IT1246350B (it) 1990-07-11 1990-07-11 Metodo per ottenere una rapida sospensione in acqua di farmaci insolubili
PCT/EP1991/001268 WO1992000731A1 (en) 1990-07-11 1991-07-04 Pharmaceutical composition for rapid suspension in water

Publications (2)

Publication Number Publication Date
DE69105106D1 true DE69105106D1 (de) 1994-12-15
DE69105106T2 DE69105106T2 (de) 1995-04-27

Family

ID=11173904

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69105106T Expired - Fee Related DE69105106T2 (de) 1990-07-11 1991-07-04 Im wasser schnell suspendierbare pharmazeutische zusammensetzung.

Country Status (16)

Country Link
US (1) US5306506A (de)
EP (1) EP0491910B1 (de)
JP (1) JP2552785B2 (de)
KR (1) KR100209175B1 (de)
AT (1) ATE113832T1 (de)
AU (1) AU640253B2 (de)
CA (1) CA2046679C (de)
DE (1) DE69105106T2 (de)
DK (1) DK0491910T3 (de)
ES (1) ES2064112T3 (de)
IE (1) IE66048B1 (de)
IT (1) IT1246350B (de)
NZ (1) NZ238901A (de)
PT (1) PT98272B (de)
WO (1) WO1992000731A1 (de)
ZA (1) ZA915284B (de)

Families Citing this family (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0662320T3 (da) * 1991-08-30 2001-09-24 Showa Pharm Chem Ind Tør gelsammensætning
US6582728B1 (en) * 1992-07-08 2003-06-24 Inhale Therapeutic Systems, Inc. Spray drying of macromolecules to produce inhaleable dry powders
US6673335B1 (en) * 1992-07-08 2004-01-06 Nektar Therapeutics Compositions and methods for the pulmonary delivery of aerosolized medicaments
DE69332105T2 (de) * 1992-09-29 2003-03-06 Inhale Therapeutic Systems San Pulmonale abgabe von aktiven fragmenten des parathormons
ES2091654T3 (es) * 1993-04-15 1996-11-01 Gergely Gerhard Sistema efervescente que contiene un ingrediente activo farmaceutico sensible a alcalis y/o metales, y procedimiento para su produccion.
DK0642784T3 (da) * 1993-09-07 1999-11-22 Gergely Gerhard Bruseblanding med alkalisalte eller lysinater af uopløseligt eller tungtopløseligt aktivstof
FR2712809B1 (fr) * 1993-11-26 1996-04-12 Union Pharma Scient Appl Nouvelle composition pharmaceutique destinée à la préparation d'une poudre stable contenant, à titre d'ingrédient actif, une association d'acide acétylsalicylique et de métoclopramide.
MX9603936A (es) * 1994-03-07 1997-05-31 Inhale Therapeutic Syst Metodos y composiciones para el suministro pulmonar de insulina.
US20030113273A1 (en) * 1996-06-17 2003-06-19 Patton John S. Methods and compositions for pulmonary delivery of insulin
DE69514403T2 (de) * 1994-04-11 2004-01-15 Dsm Nv Stabile Natamycin-Suspensionen
AU696387B2 (en) * 1994-05-18 1998-09-10 Inhale Therapeutic Systems, Inc. Methods and compositions for the dry powder formulation of interferons
WO1995033490A1 (en) * 1994-06-02 1995-12-14 Enzon, Inc. Method of solubilizing substantially water insoluble materials
US6586006B2 (en) 1994-08-04 2003-07-01 Elan Drug Delivery Limited Solid delivery systems for controlled release of molecules incorporated therein and methods of making same
US6290991B1 (en) * 1994-12-02 2001-09-18 Quandrant Holdings Cambridge Limited Solid dose delivery vehicle and methods of making same
AU3570495A (en) 1994-09-22 1996-04-09 Quadrant Holdings Cambridge Limited Compositions for use in rehydration and nutrition during athletic exercise and methods of making same
US5639475A (en) * 1995-02-03 1997-06-17 Eurand America, Incorporated Effervescent microcapsules
BE1009380A3 (nl) * 1995-03-14 1997-03-04 Universiteit Gent Lab Voor Far Stabiliserend samenstelling voor suspensie.
US6964771B1 (en) * 1995-06-07 2005-11-15 Elan Drug Delivery Limited Method for stably incorporating substances within dry, foamed glass matrices
US5560928A (en) * 1995-06-23 1996-10-01 Defelice; Stephen L. Nutritional and/or dietary composition and method of using the same
US5958455A (en) * 1996-02-09 1999-09-28 Quadrant Holdings Cambridge Ltd Oral solid dosage forms, methods of making same and compositions thereof
US5762961A (en) * 1996-02-09 1998-06-09 Quadrant Holdings Cambridge Ltd. Rapidly soluble oral solid dosage forms, methods of making same, and compositions thereof
US6632648B1 (en) * 1996-05-14 2003-10-14 Elan Drug Delivery Limited Methods of terminal sterilization of fibrinogen
US5712310A (en) * 1996-06-14 1998-01-27 Alpharma Uspd, Inc. Suspension of substantially water-insoluble drugs and methods of their manufacture
FR2753097A1 (fr) * 1996-09-11 1998-03-13 Barrau Francois Gel aqueux ou hydroalcoolique extemporane a viscosite controlee
GB2318511A (en) * 1996-10-23 1998-04-29 Eurand Int Process for the preparation of a pharmaceutical composition for rapid suspension in water
US6468782B1 (en) * 1996-12-05 2002-10-22 Quadrant Healthcare (Uk) Limited Methods of preserving prokaryotic cells and compositions obtained thereby
US20030035778A1 (en) * 1997-07-14 2003-02-20 Robert Platz Methods and compositions for the dry powder formulation of interferon
IN186245B (de) 1997-09-19 2001-07-14 Ranbaxy Lab Ltd
US6309623B1 (en) * 1997-09-29 2001-10-30 Inhale Therapeutic Systems, Inc. Stabilized preparations for use in metered dose inhalers
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6565885B1 (en) 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
NZ333474A (en) 1998-01-02 1999-06-29 Mcneil Ppc Inc A chewable tablet containing ibuprofen, fumaric acid and a non hydrocolloid binder e.g. a wax or a fat
US6432448B1 (en) 1999-02-08 2002-08-13 Fmc Corporation Edible coating composition
US6723342B1 (en) 1999-02-08 2004-04-20 Fmc Corporation Edible coating composition
US6500462B1 (en) * 1999-10-29 2002-12-31 Fmc Corporation Edible MCC/PGA coating composition
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
US8404217B2 (en) 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
AU6124601A (en) 2000-05-10 2001-11-20 Alliance Pharmaceutical Corporation Phospholipid-based powders for drug delivery
IL136899A0 (en) * 2000-06-20 2001-06-14 Caretec Ltd Microcapsules containing arginine and the different uses thereof
IT1319655B1 (it) 2000-11-15 2003-10-23 Eurand Int Microsfere di enzimi pancreatici con elevata stabilita' e relativometodo di preparazione.
BR0115585A (pt) 2000-11-28 2005-12-13 Fmc Corp Composições de revestimento de pronta liberação, endurecìvel, comestìvel, seca e, úmida, forma de dosagem sólida, e, método para revestir uma forma de dosagem sólida farmacêutica ou veterinária, confeito, semente, ração animal, fertilizante, comprimido de pesticida ou alimento
US6932861B2 (en) * 2000-11-28 2005-08-23 Fmc Corporation Edible PGA coating composition
US9700866B2 (en) 2000-12-22 2017-07-11 Baxter International Inc. Surfactant systems for delivery of organic compounds
US8067032B2 (en) 2000-12-22 2011-11-29 Baxter International Inc. Method for preparing submicron particles of antineoplastic agents
TWI327474B (en) 2001-04-06 2010-07-21 Neochemir Inc Kit for preparation of carbon dioxide agent for external use.
CA2461349C (en) 2001-09-26 2011-11-29 Baxter International Inc. Preparation of submicron sized nanoparticles via dispersion and solvent or liquid phase removal
US20060003012A9 (en) 2001-09-26 2006-01-05 Sean Brynjelsen Preparation of submicron solid particle suspensions by sonication of multiphase systems
JP2005514393A (ja) 2001-12-19 2005-05-19 ネクター セラピューティクス アミノグリコシドの肺への供給
ITMI20022358A1 (it) * 2002-11-07 2004-05-08 Bsd Bioscience Dev Snc Composizioni farmaceutiche effervescenti per la realizzazione di sospensioni non convenzionali.
US20040170686A1 (en) * 2003-01-31 2004-09-02 Fredrickson Jennifer K. Suspension vehicle for coated drug particles
US20040191326A1 (en) * 2003-03-31 2004-09-30 Reo Joseph P. Taste-masking vehicle for coated oxazolidinone particles
US20050095320A1 (en) * 2003-10-29 2005-05-05 Richard Botteri [An Isotonic Sports Drink for Female Athletes Fortified with Iron, Calcium and Essential Vitamins for Use in Rehydration and Nutrition During Execise and Competition]
US20050100636A1 (en) * 2003-11-10 2005-05-12 Megan Botteri [A Low-Calorie Sports Drink For Physically Active Women That is Fortified with Iron, Calcium and Essential Vitamins for Use in Rehydration and Replacing Electrolytes Lost During Periods of Physical Activity]
US20060134210A1 (en) * 2004-12-22 2006-06-22 Astrazeneca Ab Solid dosage form comprising proton pump inhibitor and suspension made thereof
US20070031342A1 (en) * 2005-06-22 2007-02-08 Nektar Therapeutics Sustained release microparticles for pulmonary delivery
PL2079445T3 (pl) * 2007-02-20 2016-04-29 Allergan Pharmaceuticals Int Ltd Stabilne kompozycje enzymów trawiennych
US10087493B2 (en) 2008-03-07 2018-10-02 Aptalis Pharma Canada Ulc Method for detecting infectious parvovirus in pharmaceutical preparations
US7782646B2 (en) * 2008-06-30 2010-08-24 International Business Machines Corporation High density content addressable memory using phase change devices
KR101968457B1 (ko) 2010-10-01 2019-04-11 앨러간 파마슈티컬스 인터내셔널 리미티드 장용 코팅된 저 강도 췌장 리파제 제제
RU2016119726A (ru) 2011-08-08 2018-11-02 Апталис Фарма Лтд. Способ проведения теста на растворение твердых композиций, содержащих пищеварительные ферменты
KR101383908B1 (ko) 2012-10-29 2014-04-10 씨앤텍 주식회사 이산화탄소를 피부에 공급하는 팩과 그 제조방법
JP5993336B2 (ja) * 2013-04-26 2016-09-14 株式会社メディオン・リサーチ・ラボラトリーズ 二酸化炭素経皮・経粘膜吸収用組成物
US10184121B2 (en) 2013-06-28 2019-01-22 Allergan Pharmaceuticals International Limited Methods for removing viral contaminants from pancreatic extracts
ES2784227T3 (es) 2013-08-09 2020-09-23 Allergan Pharmaceuticals Int Ltd Composición de enzimas digestivos adecuada para la administración entérica
US10836837B2 (en) 2015-11-26 2020-11-17 Novozymes A/S Wet milling process

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2125577A (en) * 1936-09-10 1938-08-02 Matsumae Akiyoshi Auxiliary medical agent and method of preparing the same
US3928252A (en) * 1971-12-10 1975-12-23 Adolph S Ltd Thickened food
DE3440288A1 (de) * 1984-11-05 1986-05-07 Gergely, Gerhard, Dr.-Ing., Wien Pharmazeutische zubereitung mit einem gehalt an mindestens einer schleimhautreizenden substanz oder dergleichen, insbesondere profen, sowie verfahren zu ihrer herstellung
IT1183574B (it) * 1985-05-08 1987-10-22 Eurand Spa Metodo per ottenere una sospensione estemporanea omogenea di microcapsule
GB8528195D0 (en) * 1985-11-15 1985-12-18 Boots Co Plc Therapeutic compositions

Also Published As

Publication number Publication date
JPH05501421A (ja) 1993-03-18
PT98272A (pt) 1992-05-29
ES2064112T3 (es) 1995-01-16
IE66048B1 (en) 1995-12-13
IT9020908A1 (it) 1992-01-11
ATE113832T1 (de) 1994-11-15
KR920702215A (ko) 1992-09-03
NZ238901A (en) 1992-08-26
CA2046679A1 (en) 1992-01-12
ZA915284B (en) 1993-03-31
IE912382A1 (en) 1992-01-15
AU8183391A (en) 1992-02-04
JP2552785B2 (ja) 1996-11-13
WO1992000731A1 (en) 1992-01-23
IT9020908A0 (it) 1990-07-11
KR100209175B1 (ko) 1999-07-15
CA2046679C (en) 2001-11-20
PT98272B (pt) 1999-01-29
DE69105106T2 (de) 1995-04-27
AU640253B2 (en) 1993-08-19
US5306506A (en) 1994-04-26
EP0491910A1 (de) 1992-07-01
IT1246350B (it) 1994-11-17
DK0491910T3 (da) 1995-01-09
EP0491910B1 (de) 1994-11-09

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee