DE69019481T2 - Aminosäurederivate. - Google Patents

Aminosäurederivate.

Info

Publication number
DE69019481T2
DE69019481T2 DE69019481T DE69019481T DE69019481T2 DE 69019481 T2 DE69019481 T2 DE 69019481T2 DE 69019481 T DE69019481 T DE 69019481T DE 69019481 T DE69019481 T DE 69019481T DE 69019481 T2 DE69019481 T2 DE 69019481T2
Authority
DE
Germany
Prior art keywords
amino acid
acid derivatives
quinolylcarbonyl
prophylaxis
medicaments
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69019481T
Other languages
English (en)
Other versions
DE69019481D1 (de
Inventor
Joseph Armstrong Martin
Sally Redshaw
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of DE69019481D1 publication Critical patent/DE69019481D1/de
Publication of DE69019481T2 publication Critical patent/DE69019481T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/021—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)n-C(=0)-, n being 5 or 6; for n > 6, classification in C07K5/06 - C07K5/10, according to the moiety having normal peptide bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
DE69019481T 1989-12-11 1990-12-10 Aminosäurederivate. Expired - Lifetime DE69019481T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB898927913A GB8927913D0 (en) 1989-12-11 1989-12-11 Amino acid derivatives
SG120493A SG120493G (en) 1989-12-11 1993-11-02 N-tert-Butyl-decahydro-2(3-amino-2-hydroxy-4-phenyl-butyl) isoquinoline-3-carboxamide and asparaginyl derivatives thereof

Publications (2)

Publication Number Publication Date
DE69019481D1 DE69019481D1 (de) 1995-06-22
DE69019481T2 true DE69019481T2 (de) 1995-11-09

Family

ID=26296345

Family Applications (2)

Application Number Title Priority Date Filing Date
DE1996175051 Active DE19675051I2 (de) 1989-12-11 1990-12-10 Aminosaeurederivate
DE69019481T Expired - Lifetime DE69019481T2 (de) 1989-12-11 1990-12-10 Aminosäurederivate.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE1996175051 Active DE19675051I2 (de) 1989-12-11 1990-12-10 Aminosaeurederivate

Country Status (48)

Country Link
US (1) US5196438A (de)
EP (1) EP0432695B1 (de)
JP (1) JP2807093B2 (de)
KR (1) KR970005912B1 (de)
CN (2) CN1066329C (de)
AT (1) ATE122661T1 (de)
AU (1) AU634319B2 (de)
BG (1) BG51452A3 (de)
BR (1) BR9006264A (de)
CA (1) CA2030433C (de)
CU (1) CU22305A3 (de)
CZ (1) CZ280558B6 (de)
DE (2) DE19675051I2 (de)
DK (1) DK0432695T3 (de)
DZ (1) DZ1467A1 (de)
EG (1) EG19722A (de)
ES (1) ES2072959T3 (de)
FI (2) FI100883B (de)
GB (2) GB8927913D0 (de)
GR (1) GR3017114T3 (de)
HK (1) HK129093A (de)
HR (1) HRP930341B1 (de)
HU (2) HU207298B (de)
ID (1) ID1018B (de)
IE (1) IE67523B1 (de)
IL (1) IL96550A (de)
IN (1) IN172553B (de)
IS (1) IS1803B (de)
LT (1) LT3682B (de)
LU (1) LU90014I2 (de)
LV (1) LV5738B4 (de)
MA (1) MA22014A1 (de)
MC (1) MC2195A1 (de)
MT (1) MTP1075B (de)
MW (1) MW8890A1 (de)
MX (1) MX173630B (de)
NL (1) NL970013I2 (de)
NO (1) NO176566C (de)
OA (1) OA09334A (de)
PL (1) PL165225B1 (de)
PT (1) PT96145B (de)
RO (1) RO107942B1 (de)
RU (1) RU2071470C1 (de)
SG (1) SG120493G (de)
SI (1) SI9012315B (de)
SK (1) SK576590A3 (de)
ZA (1) ZA909743B (de)
ZW (1) ZW17490A1 (de)

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FI973895A (fi) 1997-10-06
CN1066329C (zh) 2001-05-30
PT96145A (pt) 1991-09-30
FI905983A0 (fi) 1990-12-04
OA09334A (fr) 1992-09-15
HU207298B (en) 1993-03-29
NO176566B (no) 1995-01-16
CN1138983A (zh) 1997-01-01
LT3682B (en) 1996-01-25
NL970013I2 (nl) 1997-09-01
EP0432695A2 (de) 1991-06-19
FI973895A0 (fi) 1997-10-06
IS1803B (is) 2002-02-26
GR3017114T3 (en) 1995-11-30
LU90014I2 (fr) 1997-01-31
ES2072959T3 (es) 1995-08-01
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BG51452A3 (en) 1993-05-14
KR970005912B1 (en) 1997-04-22
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ID1018B (id) 1996-10-18
SK280249B6 (sk) 1999-10-08
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MC2195A1 (fr) 1992-10-05
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