DE68929153D1 - Gerät zum Verabreichen von Medikamenten - Google Patents

Gerät zum Verabreichen von Medikamenten

Info

Publication number
DE68929153D1
DE68929153D1 DE68929153T DE68929153T DE68929153D1 DE 68929153 D1 DE68929153 D1 DE 68929153D1 DE 68929153 T DE68929153 T DE 68929153T DE 68929153 T DE68929153 T DE 68929153T DE 68929153 D1 DE68929153 D1 DE 68929153D1
Authority
DE
Germany
Prior art keywords
patient
housing
aerosolized
flow rate
volumetric flow
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68929153T
Other languages
English (en)
Other versions
DE68929153T2 (de
Inventor
Bart Joseph Zoltan
Beth Louise Laube
Iii George Kenneth Adams
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Johns Hopkins University
Original Assignee
Johns Hopkins University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johns Hopkins University filed Critical Johns Hopkins University
Application granted granted Critical
Publication of DE68929153D1 publication Critical patent/DE68929153D1/de
Publication of DE68929153T2 publication Critical patent/DE68929153T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0086—Inhalation chambers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0086—Inhalation chambers
    • A61M15/0088—Inhalation chambers with variable volume
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/20—Valves specially adapted to medical respiratory devices
    • A61M16/208—Non-controlled one-way valves, e.g. exhalation, check, pop-off non-rebreathing valves
DE68929153T 1988-09-30 1989-09-26 Gerät zum Verabreichen von Medikamenten Expired - Fee Related DE68929153T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07251454 US4926852B1 (en) 1986-06-23 1988-09-30 Medication delivery system phase one

Publications (2)

Publication Number Publication Date
DE68929153D1 true DE68929153D1 (de) 2000-03-09
DE68929153T2 DE68929153T2 (de) 2000-06-29

Family

ID=22952042

Family Applications (2)

Application Number Title Priority Date Filing Date
DE68929153T Expired - Fee Related DE68929153T2 (de) 1988-09-30 1989-09-26 Gerät zum Verabreichen von Medikamenten
DE68915380T Expired - Fee Related DE68915380T2 (de) 1988-09-30 1989-09-26 System zum Verabreichen von Medikamenten.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE68915380T Expired - Fee Related DE68915380T2 (de) 1988-09-30 1989-09-26 System zum Verabreichen von Medikamenten.

Country Status (8)

Country Link
US (1) US4926852B1 (de)
EP (2) EP0574038B1 (de)
JP (1) JP2930988B2 (de)
AT (2) ATE105718T1 (de)
CA (1) CA1327298C (de)
DE (2) DE68929153T2 (de)
ES (2) ES2142324T3 (de)
GR (1) GR3033066T3 (de)

Families Citing this family (145)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8908647D0 (en) * 1989-04-17 1989-06-01 Glaxo Group Ltd Device
US5239991A (en) * 1989-06-21 1993-08-31 Fisons Plc Disposable powder medicament inhalation device with peel-off cover
US5178138A (en) * 1990-09-11 1993-01-12 Walstrom Dennis R Drug delivery device
US5040527A (en) * 1990-12-18 1991-08-20 Healthscan Products Inc. Metered dose inhalation unit with slide means
US5404871A (en) * 1991-03-05 1995-04-11 Aradigm Delivery of aerosol medications for inspiration
JP3532204B2 (ja) * 1991-03-05 2004-05-31 アラダイム コーポレーション 流量計の圧力センサのドリフトオフセットを補正する方法および装置
US5394866A (en) * 1991-03-05 1995-03-07 Aradigm Corporation Automatic aerosol medication delivery system and methods
US5392768A (en) * 1991-03-05 1995-02-28 Aradigm Method and apparatus for releasing a controlled amount of aerosol medication over a selectable time interval
US5450336A (en) * 1991-03-05 1995-09-12 Aradigm Corporation Method for correcting the drift offset of a transducer
ATE359842T1 (de) * 1991-07-02 2007-05-15 Nektar Therapeutics Abgabevorrichtung für nebelförmige medikamente
US6681767B1 (en) 1991-07-02 2004-01-27 Nektar Therapeutics Method and device for delivering aerosolized medicaments
JPH05123398A (ja) * 1991-11-06 1993-05-21 Tsunemasa Kamiyama 咽喉保護吸入剤並びに吸入器具
US5297543A (en) * 1992-06-24 1994-03-29 Healthscan Products, Inc. Medication inhaler mixer
US6582728B1 (en) 1992-07-08 2003-06-24 Inhale Therapeutic Systems, Inc. Spray drying of macromolecules to produce inhaleable dry powders
US6509006B1 (en) 1992-07-08 2003-01-21 Inhale Therapeutic Systems, Inc. Devices compositions and methods for the pulmonary delivery of aerosolized medicaments
US6098620A (en) * 1993-01-29 2000-08-08 Aradigm Corporation Device for aerosolizing narcotics
US5934272A (en) * 1993-01-29 1999-08-10 Aradigm Corporation Device and method of creating aerosolized mist of respiratory drug
US5873358A (en) * 1993-01-29 1999-02-23 Aradigm Corporation Method of maintaining a diabetic patient's blood glucose level in a desired range
US6012450A (en) * 1993-01-29 2000-01-11 Aradigm Corporation Intrapulmonary delivery of hematopoietic drug
US5558085A (en) * 1993-01-29 1996-09-24 Aradigm Corporation Intrapulmonary delivery of peptide drugs
US5743250A (en) * 1993-01-29 1998-04-28 Aradigm Corporation Insulin delivery enhanced by coached breathing
US5672581A (en) * 1993-01-29 1997-09-30 Aradigm Corporation Method of administration of insulin
US5819726A (en) * 1993-01-29 1998-10-13 Aradigm Corporation Method for the delivery of aerosolized drugs to the lung for the treatment of respiratory disease
US5915378A (en) * 1993-01-29 1999-06-29 Aradigm Corporation Creating an aerosolized formulation of insulin
US5724957A (en) * 1993-01-29 1998-03-10 Aradigm Corporation Intrapulmonary delivery of narcotics
US6131567A (en) * 1993-01-29 2000-10-17 Aradigm Corporation Method of use of monomeric insulin as a means for improving the reproducibility of inhaled insulin
US5970973A (en) * 1993-01-29 1999-10-26 Aradigm Corporation Method of delivering insulin lispro
US5888477A (en) * 1993-01-29 1999-03-30 Aradigm Corporation Use of monomeric insulin as a means for improving the bioavailability of inhaled insulin
US6024090A (en) 1993-01-29 2000-02-15 Aradigm Corporation Method of treating a diabetic patient by aerosolized administration of insulin lispro
US7448375B2 (en) * 1993-01-29 2008-11-11 Aradigm Corporation Method of treating diabetes mellitus in a patient
US5318016A (en) * 1993-03-30 1994-06-07 We Pharmaceuticals, Inc. Inhalation device
US5497763A (en) * 1993-05-21 1996-03-12 Aradigm Corporation Disposable package for intrapulmonary delivery of aerosolized formulations
US5709202A (en) * 1993-05-21 1998-01-20 Aradigm Corporation Intrapulmonary delivery of aerosolized formulations
US6794357B1 (en) * 1993-06-24 2004-09-21 Astrazeneca Ab Compositions for inhalation
US5830853A (en) 1994-06-23 1998-11-03 Astra Aktiebolag Systemic administration of a therapeutic preparation
US20010003739A1 (en) * 1993-06-24 2001-06-14 Astrazeneca Ab Systemic administration of a therapeutic preparation
US6632456B1 (en) 1993-06-24 2003-10-14 Astrazeneca Ab Compositions for inhalation
US5752502A (en) * 1993-12-16 1998-05-19 King; Russell Wayne General purpose aerosol inhalation apparatus
US6051256A (en) * 1994-03-07 2000-04-18 Inhale Therapeutic Systems Dispersible macromolecule compositions and methods for their preparation and use
AU689217B2 (en) * 1994-03-07 1998-03-26 Novartis Ag Methods and compositions for pulmonary delivery of insulin
US5477849A (en) * 1994-05-31 1995-12-26 Fry; Stephen Spacer for medication inhaler
US6165976A (en) 1994-06-23 2000-12-26 Astra Aktiebolag Therapeutic preparation for inhalation
US5509404A (en) * 1994-07-11 1996-04-23 Aradigm Corporation Intrapulmonary drug delivery within therapeutically relevant inspiratory flow/volume values
US6290991B1 (en) 1994-12-02 2001-09-18 Quandrant Holdings Cambridge Limited Solid dose delivery vehicle and methods of making same
ES2302332T3 (es) 1994-09-21 2008-07-01 Nektar Therapeutics Aparato y metodos para dispersar medicamentos en polvo seco.
DE4438292C2 (de) * 1994-10-26 1999-07-22 Pari Gmbh Dosisgenaue Aerosolerzeugung für die Inhalationstherapie
EP1177807A3 (de) * 1994-10-28 2003-10-22 Aradigm Corporation Vorrichtung und Verfahren zum Herstellen von Aerosolnebel aus einem atmungserleichternden Arzneimittel
BR9510510A (pt) 1994-12-22 1998-07-07 Astra Ab Formulação em aerossol farmacêutica uso da mesma e processos para fabricação da mesma para tratamento de um paciente carente de terapia
US6524557B1 (en) * 1994-12-22 2003-02-25 Astrazeneca Ab Aerosol formulations of peptides and proteins
US5571246A (en) * 1995-02-16 1996-11-05 Alldredge; Andrew L. Collapsible metered dose inhaler
US5780014A (en) * 1995-04-14 1998-07-14 Inhale Therapeutic Systems Method and apparatus for pulmonary administration of dry powder alpha 1-antitrypsin
GB9510535D0 (en) * 1995-05-24 1995-07-19 Sovereign Surgical Ltd Improvements relating to respiratory appratus
US20030203036A1 (en) * 2000-03-17 2003-10-30 Gordon Marc S. Systems and processes for spray drying hydrophobic drugs with hydrophilic excipients
US6725859B1 (en) * 1997-01-22 2004-04-27 Charles River Laboratories Apparatus for delivering air-borne substances
GEP20043260B (en) * 1998-03-16 2004-06-25 Nectar Therapeutics Aerosolized Active Agent Delivery and Device for Realization Thereof
US6257233B1 (en) 1998-06-04 2001-07-10 Inhale Therapeutic Systems Dry powder dispersing apparatus and methods for their use
UA73924C2 (en) * 1998-10-09 2005-10-17 Nektar Therapeutics Device for delivering active agent formulation to lungs of human patient
US6234167B1 (en) 1998-10-14 2001-05-22 Chrysalis Technologies, Incorporated Aerosol generator and methods of making and using an aerosol generator
EP1196263A4 (de) 1998-11-16 2004-10-27 Aradigm Corp Herstellungsverfahren einer porösen membran mit einer einzelnen porenstruktur zur verabreichung von arzneistoffen in aerosolform
US6615826B1 (en) * 1999-02-26 2003-09-09 3M Innovative Properties Company Slow spray metered dose inhaler
AU5026100A (en) * 1999-05-20 2000-12-12 Scios Inc. Vascular endothelial growth factor dimers
DE60027714T3 (de) 1999-05-20 2008-01-24 Kos Life Sciences, Inc., Weston Zerstäubungssystem mit niedriger spraykraft und retention
JP2003507006A (ja) 1999-05-20 2003-02-25 サイオス，インコーポレーテッド 血管内皮増殖因子改変体
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
US6606992B1 (en) 1999-06-30 2003-08-19 Nektar Therapeutics Systems and methods for aerosolizing pharmaceutical formulations
US7305986B1 (en) 1999-07-23 2007-12-11 Mannkind Corporation Unit dose capsules for use in a dry powder inhaler
US7464706B2 (en) 1999-07-23 2008-12-16 Mannkind Corporation Unit dose cartridge and dry powder inhaler
DE19944208C1 (de) 1999-09-15 2001-09-06 Transmit Technologietransfer Kombinationsmundstück für Inhalationstherapiegeräte sauerstoffabhängiger Patienten
CN100341483C (zh) 2000-02-28 2007-10-10 维克丘拉有限公司 口服药物输递中或涉及口服药物输递的改进
WO2001074247A2 (en) 2000-04-03 2001-10-11 Iep Pharmaceutical Devices Inc. Method for measuring changes in the airways of humans and other mammals
MY136453A (en) * 2000-04-27 2008-10-31 Philip Morris Usa Inc "improved method and apparatus for generating an aerosol"
US6883516B2 (en) 2000-04-27 2005-04-26 Chrysalis Technologies Incorporated Method for generating an aerosol with a predetermined and/or substantially monodispersed particle size distribution
US6453900B1 (en) 2000-06-09 2002-09-24 Pulmonary Services, Inc. Inhaler device
US7575761B2 (en) * 2000-06-30 2009-08-18 Novartis Pharma Ag Spray drying process control of drying kinetics
US6701921B2 (en) 2000-12-22 2004-03-09 Chrysalis Technologies Incorporated Aerosol generator having heater in multilayered composite and method of use thereof
US6681998B2 (en) 2000-12-22 2004-01-27 Chrysalis Technologies Incorporated Aerosol generator having inductive heater and method of use thereof
US6501052B2 (en) 2000-12-22 2002-12-31 Chrysalis Technologies Incorporated Aerosol generator having multiple heating zones and methods of use thereof
US6799572B2 (en) 2000-12-22 2004-10-05 Chrysalis Technologies Incorporated Disposable aerosol generator system and methods for administering the aerosol
US6491233B2 (en) 2000-12-22 2002-12-10 Chrysalis Technologies Incorporated Vapor driven aerosol generator and method of use thereof
US7077130B2 (en) 2000-12-22 2006-07-18 Chrysalis Technologies Incorporated Disposable inhaler system
US6595204B2 (en) 2001-03-01 2003-07-22 Iep Pharmaceutical Devices Inc. Spacer for an inhaler
US6698422B2 (en) 2001-03-12 2004-03-02 Birdsong Medical Devices, Inc. Canister inhaler having a spacer and easy to operate lever mechanism and a flexible, elastic mouthpiece
US6523536B2 (en) * 2001-03-12 2003-02-25 Birdsong Medical Devices, Inc. Dual-canister inhaler having a spacer and easy to operate lever mechanism
AU2002254753C1 (en) 2001-05-01 2008-09-18 The Regents Of The University Of California Fusion molecules and methods for treatment of immune diseases
US7265208B2 (en) 2001-05-01 2007-09-04 The Regents Of The University Of California Fusion molecules and treatment of IgE-mediated allergic diseases
WO2003022332A2 (en) * 2001-09-06 2003-03-20 Microdose Technologies, Inc. Adaptors for inhalers to improve performance
US6568390B2 (en) 2001-09-21 2003-05-27 Chrysalis Technologies Incorporated Dual capillary fluid vaporizing device
US6640050B2 (en) 2001-09-21 2003-10-28 Chrysalis Technologies Incorporated Fluid vaporizing device having controlled temperature profile heater/capillary tube
US6681769B2 (en) 2001-12-06 2004-01-27 Crysalis Technologies Incorporated Aerosol generator having a multiple path heater arrangement and method of use thereof
US6804458B2 (en) 2001-12-06 2004-10-12 Chrysalis Technologies Incorporated Aerosol generator having heater arranged to vaporize fluid in fluid passage between bonded layers of laminate
US6701922B2 (en) 2001-12-20 2004-03-09 Chrysalis Technologies Incorporated Mouthpiece entrainment airflow control for aerosol generators
US6705316B2 (en) 2002-03-11 2004-03-16 Battelle Pulmonary Therapeutics, Inc. Pulmonary dosing system and method
WO2003080149A2 (en) 2002-03-20 2003-10-02 Mannkind Corporation Inhalation apparatus
GB0216562D0 (en) * 2002-04-25 2002-08-28 Bradford Particle Design Ltd Particulate materials
US9339459B2 (en) 2003-04-24 2016-05-17 Nektar Therapeutics Particulate materials
US7185651B2 (en) * 2002-06-18 2007-03-06 Nektar Therapeutics Flow regulator for aerosol drug delivery and methods
US20030236489A1 (en) 2002-06-21 2003-12-25 Baxter International, Inc. Method and apparatus for closed-loop flow control system
US7367334B2 (en) 2003-08-27 2008-05-06 Philip Morris Usa Inc. Fluid vaporizing device having controlled temperature profile heater/capillary tube
JP5078014B2 (ja) 2004-08-20 2012-11-21 マンカインド コーポレイション ジケトピペラジン合成の触媒反応
HUE026797T2 (en) 2004-08-23 2016-07-28 Mannkind Corp Diceto-piperazine salts for drug delivery
US7488804B2 (en) * 2005-02-02 2009-02-10 The Regents Of The University Of California Modified fusion molecules for treatment of allergic disease
CN101500482B (zh) * 2005-05-10 2012-06-20 恩斯拜尔保健公司 用于分析肺性能的方法和设备
SI2594272T1 (sl) 2005-05-18 2018-10-30 Horizon Orphan Llc Aerosolizirani fluorokinoloni in njih uporaba
US8546423B2 (en) * 2005-05-18 2013-10-01 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
KR20120060245A (ko) 2005-09-14 2012-06-11 맨카인드 코포레이션 활성제에 대한 결정질 미립자 표면의 친화력의 증가를 기반으로 하는 약물 제제화의 방법
EP2497484A3 (de) 2006-02-22 2012-11-07 MannKind Corporation Verfahren zur Verbesserung der pharmazeutischen Eigenschaften von Mikropartikeln mit Diketopiperazin und einem Wirkstoff
US8413651B2 (en) * 2007-04-06 2013-04-09 Becton, Dickinson And Company Disposable spacer for inhalation delivery of aerosolized drugs and vaccines
RU2480248C2 (ru) * 2007-06-15 2013-04-27 Бёрингер Ингельхайм Интернациональ Гмбх Ингалятор
EP2534957B1 (de) 2007-12-14 2015-05-27 AeroDesigns, Inc Abgabe von Aerosol-sprühbaren Produkten
JP5667041B2 (ja) * 2008-03-27 2015-02-12 マンカインド コーポレイション 乾燥粉末吸入システム
EP3281663B8 (de) 2008-06-13 2022-09-21 MannKind Corporation Atemluftbetriebener trockenpulverinhalator zur verabreichung von medikamenten
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
US9364619B2 (en) 2008-06-20 2016-06-14 Mannkind Corporation Interactive apparatus and method for real-time profiling of inhalation efforts
TWI494123B (zh) 2008-08-11 2015-08-01 Mannkind Corp 超快起作用胰島素之用途
PT2346509T (pt) * 2008-10-07 2020-08-05 Horizon Orphan Llc Inalação de levofloxacina para redução da inflamação pulmonar
PL2344129T3 (pl) 2008-10-07 2018-07-31 Horizon Orphan Llc Formulacje fluorochinolonu w aerozolu dla poprawy właściwości farmakokinetycznych
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
CA2754595C (en) 2009-03-11 2017-06-27 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
WO2010144789A2 (en) 2009-06-12 2010-12-16 Mannkind Corporation Diketopiperazine microparticles with defined specific surface areas
AU2010289326B2 (en) 2009-09-04 2015-09-24 Horizon Therapeutics U.S. Holding Llc Use of aerosolized levofloxacin for treating cystic fibrosis
CA2778698A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
AU2011271097B2 (en) 2010-06-21 2014-11-27 Mannkind Corporation Dry powder drug delivery system and methods
USD742503S1 (en) 2011-01-12 2015-11-03 Vectura Gmbh Mobile inhaler device
EP4059499A1 (de) 2011-01-31 2022-09-21 Avalyn Pharma Inc. Aerosolförmige pirfenidon- und pyridonanalogverbindungen und verwendungen davon
CN105667994B (zh) 2011-04-01 2018-04-06 曼金德公司 用于药物药盒的泡罩包装
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
KR20140095483A (ko) 2011-10-24 2014-08-01 맨카인드 코포레이션 통증을 치료하기 위한 방법 및 조성물
DK2872205T3 (en) 2012-07-12 2017-02-27 Mannkind Corp DRY POWDER FORMAL ADMINISTRATION SYSTEM
WO2014066856A1 (en) 2012-10-26 2014-05-01 Mannkind Corporation Inhalable influenza vaccine compositions and methods
KR102499439B1 (ko) 2013-03-15 2023-02-13 맨카인드 코포레이션 미세결정성 디케토피페라진 조성물 및 방법
USD732659S1 (en) 2013-03-26 2015-06-23 Pediatric Innovations USA, LLC Car-shaped nasal device
USD732658S1 (en) 2013-03-26 2015-06-23 Pediatric Innovations USA, LLC Nasal device with airplane wings
WO2015010092A1 (en) 2013-07-18 2015-01-22 Mannkind Corporation Heat-stable dry powder pharmaceutical compositions and methods
EP3027026A4 (de) 2013-07-31 2017-05-03 Windward Pharma, Inc. Aerosoltyrosinkinasehemmer-verbindungen und verwendungen davon
JP2016530930A (ja) 2013-08-05 2016-10-06 マンカインド コーポレイション 通気装置及び方法
CA2936330C (en) 2014-01-10 2023-01-03 Genoa Pharmaceuticals Inc. Aerosol pirfenidone and pyridone analog compounds and uses thereof
US10478570B2 (en) 2014-01-30 2019-11-19 Dualams, Inc. Medication delivery apparatus and accompanying system for the application of local anesthetics to a treatment site and method for use of same
WO2015148905A1 (en) 2014-03-28 2015-10-01 Mannkind Corporation Use of ultrarapid acting insulin
US8961992B1 (en) 2014-04-02 2015-02-24 Tunitas Therapeutics, Inc. Epsigam fusion protein
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
US10933208B2 (en) * 2016-11-14 2021-03-02 Vandana M. Krishna Asthma inhaler accessory
CN109464741B (zh) * 2018-12-17 2021-03-12 张淑玲 一种妇产科临床用喷射式上药装置
USD978327S1 (en) * 2021-05-07 2023-02-14 Iris Call Carlton Inhaler
WO2022240897A1 (en) 2021-05-10 2022-11-17 Sepelo Therapeutics, Llc Pharmaceutical composition comprising delafloxacin for administration into the lung
WO2023028364A1 (en) 2021-08-27 2023-03-02 Sepelo Therapeutics, Llc Targeted compositions and uses therof

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2406997A (en) * 1946-08-27 1946-09-03 Harold E Curry Atomizer
US2944546A (en) * 1954-08-24 1960-07-12 Z And W Mfg Corp Portable respirators for anesthesia and other purposes
US2788784A (en) * 1955-08-23 1957-04-16 Herbert M Birch Means for administering medication orally into the respiratory organs
US4484577A (en) * 1981-07-23 1984-11-27 Key Pharmaceuticals, Inc. Drug delivery method and inhalation device therefor
GB2110543B (en) * 1981-12-04 1985-08-07 Univ Southampton Inhalers
US4612926A (en) * 1982-07-23 1986-09-23 Battelle Development Corporation Dual-range aspirator device
US4534343A (en) * 1984-01-27 1985-08-13 Trutek Research, Inc. Metered dose inhaler
US4796614A (en) * 1987-02-26 1989-01-10 Trutek Research, Inc. Collapsible inhalation valve
DE3843056A1 (de) * 1987-12-23 1989-07-06 Mazda Motor Anordnung zur motorleistungssteuerung

Also Published As

Publication number Publication date
EP0361845A3 (de) 1991-07-03
EP0574038B1 (de) 2000-02-02
ATE105718T1 (de) 1994-06-15
GR3033066T3 (en) 2000-08-31
CA1327298C (en) 1994-03-01
US4926852B1 (en) 1995-05-23
EP0574038A3 (de) 1994-01-19
DE68915380T2 (de) 1994-09-01
DE68929153T2 (de) 2000-06-29
EP0574038A2 (de) 1993-12-15
ATE189404T1 (de) 2000-02-15
JPH02237572A (ja) 1990-09-20
ES2142324T3 (es) 2000-04-16
DE68915380D1 (de) 1994-06-23
JP2930988B2 (ja) 1999-08-09
EP0361845B1 (de) 1994-05-18
US4926852A (en) 1990-05-22
EP0361845A2 (de) 1990-04-04
ES2052926T3 (es) 1994-07-16

Similar Documents

Publication Publication Date Title
US4926852B1 (en) Medication delivery system phase one
ES2051371T3 (es) Inhalador de aerosoles.
US5355872A (en) Low flow rate nebulizer apparatus and method of nebulization
EP0592540B1 (de) Verfahren und vorrichtung zum abgeben von medikamenten in aerosolform
US5752502A (en) General purpose aerosol inhalation apparatus
US5186166A (en) Powder nebulizer apparatus and method of nebulization
FI911738A (fi) Anordning foer administrering av pulverformiga medicinska aemnen.
DK0983103T3 (da) Indretning til indgivelse af en medicinsk aerosol via lungen
EP0251443A3 (de) Vorrichtung zur Verabreichung von Medikamenten
GB1526303A (en) Device for the inhalation of medicaments

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee