DE60328496D1 - Fluorinierte chlorin und bacteriochlorin photosensitizer für fotodynamische therapie - Google Patents

Fluorinierte chlorin und bacteriochlorin photosensitizer für fotodynamische therapie

Info

Publication number
DE60328496D1
DE60328496D1 DE60328496T DE60328496T DE60328496D1 DE 60328496 D1 DE60328496 D1 DE 60328496D1 DE 60328496 T DE60328496 T DE 60328496T DE 60328496 T DE60328496 T DE 60328496T DE 60328496 D1 DE60328496 D1 DE 60328496D1
Authority
DE
Germany
Prior art keywords
fotodynamische
fluorinierte
bacteriochlorin
therapie
chlorin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60328496T
Other languages
English (en)
Inventor
Ravindra K Pandey
William R Potter
Thomas J Dougherty
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Health Research Inc
Original Assignee
Health Research Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Health Research Inc filed Critical Health Research Inc
Application granted granted Critical
Publication of DE60328496D1 publication Critical patent/DE60328496D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0076—PDT with expanded (metallo)porphyrins, i.e. having more than 20 ring atoms, e.g. texaphyrins, sapphyrins, hexaphyrins, pentaphyrins, porphocyanines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B47/00—Porphines; Azaporphines
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B69/00—Dyes not provided for by a single group of this subclass
    • C09B69/10—Polymeric dyes; Reaction products of dyes with monomers or with macromolecular compounds
    • C09B69/108—Polymeric dyes; Reaction products of dyes with monomers or with macromolecular compounds containing a phthalocyanine dye
DE60328496T 2002-06-27 2003-06-27 Fluorinierte chlorin und bacteriochlorin photosensitizer für fotodynamische therapie Expired - Lifetime DE60328496D1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39247302P 2002-06-27 2002-06-27
PCT/US2003/020427 WO2004002476A2 (en) 2002-06-27 2003-06-27 Fluorinated chlorin and bacteriochlorin photosensitizers for photodynamic therapy

Publications (1)

Publication Number Publication Date
DE60328496D1 true DE60328496D1 (en) 2009-09-03

Family

ID=30000878

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60328496T Expired - Lifetime DE60328496D1 (en) 2002-06-27 2003-06-27 Fluorinierte chlorin und bacteriochlorin photosensitizer für fotodynamische therapie

Country Status (6)

Country Link
US (5) US7166719B2 (de)
EP (1) EP1517684B1 (de)
AU (1) AU2003248747A1 (de)
CA (1) CA2490692A1 (de)
DE (1) DE60328496D1 (de)
WO (1) WO2004002476A2 (de)

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