DE60311277D1 - Benzotriazabicyclische derivate und deren verwendung als beta-lactamaseinhibitoren und antibakterielle mittel - Google Patents

Benzotriazabicyclische derivate und deren verwendung als beta-lactamaseinhibitoren und antibakterielle mittel

Info

Publication number
DE60311277D1
DE60311277D1 DE60311277T DE60311277T DE60311277D1 DE 60311277 D1 DE60311277 D1 DE 60311277D1 DE 60311277 T DE60311277 T DE 60311277T DE 60311277 T DE60311277 T DE 60311277T DE 60311277 D1 DE60311277 D1 DE 60311277D1
Authority
DE
Germany
Prior art keywords
lactamaseinhibitors
benzotriazabicyclic
beta
derivatives
antibacterial agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60311277T
Other languages
English (en)
Other versions
DE60311277T2 (de
Inventor
Branislav Musicki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Aventis Pharma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma SA filed Critical Aventis Pharma SA
Publication of DE60311277D1 publication Critical patent/DE60311277D1/de
Application granted granted Critical
Publication of DE60311277T2 publication Critical patent/DE60311277T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/28—Cinnolines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/02—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 2
DE60311277T 2002-09-05 2003-09-04 Benzotriazabicyclische derivate und deren verwendung als beta-lactamaseinhibitoren und antibakterielle mittel Expired - Fee Related DE60311277T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0210957 2002-09-05
FR0210957A FR2844273B1 (fr) 2002-09-05 2002-09-05 Nouveaux composes heterocycliques, procede et intermediaires de preparation et utilisation comme medicament, notamment comme inhibiteurs de beta-lactamases et anti-bacteriens.
PCT/FR2003/002639 WO2004022563A1 (fr) 2002-09-05 2003-09-04 Derives benzotriazabibicycliques et son utilisation comme inhibiteurs de beta-lactamases et anti-bacteriens

Publications (2)

Publication Number Publication Date
DE60311277D1 true DE60311277D1 (de) 2007-03-08
DE60311277T2 DE60311277T2 (de) 2007-11-29

Family

ID=31725838

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60311277T Expired - Fee Related DE60311277T2 (de) 2002-09-05 2003-09-04 Benzotriazabicyclische derivate und deren verwendung als beta-lactamaseinhibitoren und antibakterielle mittel

Country Status (7)

Country Link
US (2) US7365071B2 (de)
EP (1) EP1537117B1 (de)
JP (1) JP2006501258A (de)
AU (1) AU2003278254A1 (de)
DE (1) DE60311277T2 (de)
FR (1) FR2844273B1 (de)
WO (1) WO2004022563A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2844273B1 (fr) 2002-09-05 2008-04-04 Aventis Pharma Sa Nouveaux composes heterocycliques, procede et intermediaires de preparation et utilisation comme medicament, notamment comme inhibiteurs de beta-lactamases et anti-bacteriens.
US7439253B2 (en) * 2002-12-06 2008-10-21 Novexel Heterocyclic compounds, their preparation and their use as medicaments, in particular as antibacterials and beta-lactamase inhibitors
US20110046101A1 (en) * 2008-03-17 2011-02-24 Dmitrienko Gary I Bate-lactamase inhibitors
FR2936798B1 (fr) 2008-10-03 2012-09-28 Novexel Nouveaux composes heterocycliques azotes, leur preparation et leur utilisation comme medicaments antibacteriens.
FR2937034B1 (fr) 2008-10-10 2012-11-23 Novexel Nouveaux composes heterocycliques azotes, leur preparation et leur utilisation comme medicaments antibacteriens
JP2013538567A (ja) * 2010-08-12 2013-10-17 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 抗菌化合物を同定するおよび抗生物質感受性を決定する方法
US9505761B2 (en) 2011-12-02 2016-11-29 Fedora Pharmaceuticals Inc. Bicyclic compounds and their use as antibacterial agents and beta-lactamase inhibitors
US8796257B2 (en) 2011-12-02 2014-08-05 Naeja Pharmaceutical Inc. Bicyclic compounds and their use as antibacterial agents and β-lactamase inhibitors
UA111925C2 (uk) 2012-12-11 2016-06-24 Федора Фармасьютікалз Інк. БІЦИКЛІЧНІ СПОЛУКИ ТА ЇХ ВИКОРИСТАННЯ ЯК АНТИБАКТЕРІАЛЬНИХ АГЕНТІВ ТА ІНГІБІТОРІВ β-ЛАКТАМАЗИ

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FR2676230B1 (fr) 1991-05-07 1993-08-27 Centre Nat Rech Scient Nouveaux derives de pyrrolo [1,4]-benzodiazepines, leur procede de preparation et medicaments les contenant.
JPH05339263A (ja) 1992-06-08 1993-12-21 Wakunaga Pharmaceut Co Ltd ジヒドロピリジン誘導体
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US5461637A (en) * 1994-03-16 1995-10-24 Micracor, Inc. High brightness, vertical cavity semiconductor lasers
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US5568574A (en) * 1995-06-12 1996-10-22 University Of Southern California Modulator-based photonic chip-to-chip interconnections for dense three-dimensional multichip module integration
SE9504618D0 (sv) 1995-12-22 1995-12-22 Astra Ab New Compounds
FR2749585B1 (fr) * 1996-06-11 1998-08-14 Hoechst Marion Roussel Inc Nouveaux derives aromatiques substitues par un ribose, leur procede de preparation et leur application comme medicaments
DE19627431A1 (de) 1996-07-08 1998-01-15 Bayer Ag Heterocyclisch kondensierte Pyridine
US5835517A (en) * 1996-10-04 1998-11-10 W. L. Gore & Associates, Inc. WDM multiplexer-demultiplexer using Fabry-Perot filter array
US5964121A (en) * 1997-02-05 1999-10-12 Eaton Corporation Automated transmission system power-down
TW527355B (en) 1997-07-02 2003-04-11 Bristol Myers Squibb Co Inhibitors of farnesyl protein transferase
JP3684778B2 (ja) * 1997-08-21 2005-08-17 富士ゼロックス株式会社 面発光型半導体レーザアレイ
US6197339B1 (en) 1997-09-30 2001-03-06 Pharmacia & Upjohn Company Sustained release tablet formulation to treat Parkinson's disease
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WO2000000479A1 (en) 1998-06-30 2000-01-06 Du Pont Pharmaceuticals Company 1,3-benzodiazepin-2-ones and 1,3-benzoxazepin-2-ones useful as hiv reverse transcriptase inhibitors
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CZ20011900A3 (cs) 1998-12-18 2002-02-13 Schering Corporation Látka, způsob léčby a farmaceutický přípravek tuto látku obsahující a jeho pouľití k inhibici farnesyl protein transferázy
FR2792320B1 (fr) * 1999-04-19 2003-05-09 Hoechst Marion Roussel Inc Nouveaux amides aromatiques substitues par un ribose, leur procede de preparation et leur application comme medicaments
CO5180550A1 (es) 1999-04-19 2002-07-30 Smithkline Beecham Corp Inhibidores de fab i
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JP2001141924A (ja) * 1999-11-16 2001-05-25 Matsushita Electric Ind Co Ltd 分波素子及び分波受光素子
EP1288216A1 (de) 2000-04-18 2003-03-05 Sumitomo Pharmaceuticals Company, Limited Tricyclische chinazolindione
FR2812635B1 (fr) * 2000-08-01 2002-10-11 Aventis Pharma Sa Nouveaux composes heterocycliques, preparation et utilisation comme medicaments notamment comme anti- bacteriens
ES2287256T3 (es) 2001-02-22 2007-12-16 School Of Pharmacy, University Of London Indolinas y tetrahidroquinolina como profarmacos para el tratamiento de tumores.
FR2825705B1 (fr) 2001-06-08 2005-05-20 Aventis Pharma Sa Nouveaux composes heterocycliques, leur preparation et leur utilisation comme medicaments, notamment comme anti-bacteriens
US20030031218A1 (en) * 2001-08-13 2003-02-13 Jang-Hun Yeh VCSEL structure and method of making same
FR2835186B1 (fr) 2002-01-28 2006-10-20 Aventis Pharma Sa Nouveaux composes heterocycliques, actifs comme inhibiteurs de beta-lactamases
FR2844273B1 (fr) * 2002-09-05 2008-04-04 Aventis Pharma Sa Nouveaux composes heterocycliques, procede et intermediaires de preparation et utilisation comme medicament, notamment comme inhibiteurs de beta-lactamases et anti-bacteriens.
US7439253B2 (en) * 2002-12-06 2008-10-21 Novexel Heterocyclic compounds, their preparation and their use as medicaments, in particular as antibacterials and beta-lactamase inhibitors
FR2848210B1 (fr) 2002-12-06 2007-10-19 Aventis Pharma Sa Nouveaux composes heterocycliques, leur preparation et leur utilisation comme medicaments, notamment comme anti-bacteriens et inhibiteurs de beta-lactamases

Also Published As

Publication number Publication date
JP2006501258A (ja) 2006-01-12
FR2844273A1 (fr) 2004-03-12
US7365071B2 (en) 2008-04-29
EP1537117B1 (de) 2007-01-17
US20070191312A1 (en) 2007-08-16
US20040097490A1 (en) 2004-05-20
AU2003278254A1 (en) 2004-03-29
WO2004022563A1 (fr) 2004-03-18
FR2844273B1 (fr) 2008-04-04
EP1537117A1 (de) 2005-06-08
DE60311277T2 (de) 2007-11-29

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Legal Events

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8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee