DE602006012327D1 - Mittel zur funktionalen wiederherstellung eines geschädigten nervensystems - Google Patents

Mittel zur funktionalen wiederherstellung eines geschädigten nervensystems

Info

Publication number
DE602006012327D1
DE602006012327D1 DE602006012327T DE602006012327T DE602006012327D1 DE 602006012327 D1 DE602006012327 D1 DE 602006012327D1 DE 602006012327 T DE602006012327 T DE 602006012327T DE 602006012327 T DE602006012327 T DE 602006012327T DE 602006012327 D1 DE602006012327 D1 DE 602006012327D1
Authority
DE
Germany
Prior art keywords
nervous system
functional restoration
damaged nervous
microelectrodes
bridging
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602006012327T
Other languages
English (en)
Inventor
Carmen Bartic
Jean-Pierre Kruth
Bart Nuttin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KU Leuven Research and Development
Original Assignee
KU Leuven Research and Development
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0513460A external-priority patent/GB0513460D0/en
Priority claimed from GB0513684A external-priority patent/GB0513684D0/en
Application filed by KU Leuven Research and Development filed Critical KU Leuven Research and Development
Publication of DE602006012327D1 publication Critical patent/DE602006012327D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/40Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4058Detecting, measuring or recording for evaluating the nervous system for evaluating the central nervous system
    • A61B5/4064Evaluating the brain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36103Neuro-rehabilitation; Repair or reorganisation of neural tissue, e.g. after stroke
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00Nanotechnology for materials or surface science, e.g. nanocomposites
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/40Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4058Detecting, measuring or recording for evaluating the nervous system for evaluating the central nervous system
    • A61B5/407Evaluating the spinal cord
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/50Clinical applications
    • A61B6/506Clinical applications involving diagnosis of nerves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/05Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0526Head electrodes
    • A61N1/0529Electrodes for brain stimulation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/05Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0526Head electrodes
    • A61N1/0529Electrodes for brain stimulation
    • A61N1/0531Brain cortex electrodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/05Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0551Spinal or peripheral nerve electrodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36007Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of urogenital or gastrointestinal organs, e.g. for incontinence control
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B33ADDITIVE MANUFACTURING TECHNOLOGY
    • B33YADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y50/00Data acquisition or data processing for additive manufacturing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B33ADDITIVE MANUFACTURING TECHNOLOGY
    • B33YADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y80/00Products made by additive manufacturing

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pathology (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nanotechnology (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physiology (AREA)
  • Composite Materials (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • General Physics & Mathematics (AREA)
  • Materials Engineering (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Rehabilitation Therapy (AREA)
  • Psychology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Electrotherapy Devices (AREA)
  • Prostheses (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Laying Of Electric Cables Or Lines Outside (AREA)
  • Exchange Systems With Centralized Control (AREA)
  • Earth Drilling (AREA)
DE602006012327T 2005-07-01 2006-07-03 Mittel zur funktionalen wiederherstellung eines geschädigten nervensystems Active DE602006012327D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0513460A GB0513460D0 (en) 2005-07-01 2005-07-01 Functional restoration of the damaged nervous system
GB0513684A GB0513684D0 (en) 2005-07-05 2005-07-05 Functional restoration of the damaged nervous system
PCT/BE2006/000077 WO2007003019A2 (en) 2005-07-01 2006-07-03 Means for functional restoration of a damaged nervous system

Publications (1)

Publication Number Publication Date
DE602006012327D1 true DE602006012327D1 (de) 2010-04-01

Family

ID=37240989

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602006012327T Active DE602006012327D1 (de) 2005-07-01 2006-07-03 Mittel zur funktionalen wiederherstellung eines geschädigten nervensystems

Country Status (8)

Country Link
US (1) US7991465B2 (de)
EP (1) EP1909890B1 (de)
JP (1) JP4880681B2 (de)
AT (1) ATE457773T1 (de)
CA (1) CA2613694A1 (de)
DE (1) DE602006012327D1 (de)
DK (1) DK1909890T3 (de)
WO (1) WO2007003019A2 (de)

Families Citing this family (90)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2748056A1 (en) 2006-12-15 2008-06-19 Nasophlex B.V. Resuscitation device and method for resuscitation
WO2008107822A1 (en) * 2007-03-02 2008-09-12 Koninklijke Philips Electronics N.V. Electrode system for deep brain stimulation
DE102007029364A1 (de) * 2007-06-26 2009-01-02 Siemens Ag Verfahren zum Bestimmen eines Zugangs zu einem Areal von einem Gehirn
JP5126710B2 (ja) * 2007-08-22 2013-01-23 国立大学法人大阪大学 頭蓋内電極構造体およびその製造方法
NL2001694C2 (en) 2008-06-18 2009-12-22 Nasophlex B V Ear stimulator for producing a stimulation signal to an ear.
NL2001697C2 (en) 2008-06-18 2009-12-22 Nasophlex B V Nose stimulator for producing a stimulation signal to a nose.
NL2001695C2 (en) * 2008-06-18 2009-12-22 Kerphos B V An electronic system for producing a stimulation signal to the human body.
NL2001698C2 (en) 2008-06-18 2009-12-22 Nasophlex B V Cardioverter / defibrillator.
BRPI0920821B8 (pt) 2008-10-01 2021-06-22 Hua Sherwin sistema para estabilização de osso e parafuso para uso na estabilização de ossos
JP5646492B2 (ja) 2008-10-07 2014-12-24 エムシー10 インコーポレイテッドMc10,Inc. 伸縮可能な集積回路およびセンサアレイを有する装置
US8389862B2 (en) 2008-10-07 2013-03-05 Mc10, Inc. Extremely stretchable electronics
US8097926B2 (en) 2008-10-07 2012-01-17 Mc10, Inc. Systems, methods, and devices having stretchable integrated circuitry for sensing and delivering therapy
US8372726B2 (en) 2008-10-07 2013-02-12 Mc10, Inc. Methods and applications of non-planar imaging arrays
US8886334B2 (en) 2008-10-07 2014-11-11 Mc10, Inc. Systems, methods, and devices using stretchable or flexible electronics for medical applications
US9123614B2 (en) 2008-10-07 2015-09-01 Mc10, Inc. Methods and applications of non-planar imaging arrays
WO2010048189A2 (en) 2008-10-20 2010-04-29 IMDS, Inc. Systems and methods for cerebrospinal fluid repair
EP2184263A1 (de) 2008-11-06 2010-05-12 Unilever N.V. Wasseraufbereitungsvorrichtung
EP2378956A4 (de) * 2008-12-11 2017-12-27 Mc10, Inc. Systeme, verfahren und vorrichtungen mit dehnbarer oder biegsamer elektronik für medizinische anwendungen
US9723122B2 (en) 2009-10-01 2017-08-01 Mc10, Inc. Protective cases with integrated electronics
EP2353636A1 (de) * 2010-02-05 2011-08-10 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Neurologische Schnittstellensonde
US8718792B2 (en) * 2010-02-19 2014-05-06 Neuron Networks Restored, Llc System and method of repairing of neural networks
WO2011107917A1 (en) 2010-03-01 2011-09-09 Koninklijke Philips Electronics N.V. Method and system for determining settings for deep brain stimulation
KR101837481B1 (ko) * 2010-03-17 2018-03-13 더 보드 오브 트러스티즈 오브 더 유니버시티 오브 일리노이 생체흡수성 기판 상 이식가능한 바이오의료 장치
DE102010020610A1 (de) * 2010-05-14 2011-11-17 Siemens Aktiengesellschaft Strahlendetektor und Verfahren zur Herstellung eines Strahlendetektors
US11813454B2 (en) 2010-11-11 2023-11-14 IINN, Inc. Methods of bypassing neurological damage through motor nerve root stimulation
WO2012094346A2 (en) 2011-01-03 2012-07-12 The Regents Of The University Of California High density epidural stimulation for facilitation of locomotion, posture, voluntary movement, and recovery of autonomic, sexual, vasomotor, and cognitive function after neurological injury
JP2014508581A (ja) 2011-01-21 2014-04-10 カリフォルニア インスティテュート オブ テクノロジー 脊髄刺激のためのパリレンベースのマイクロ電極アレイインプラント
CN107361741B (zh) 2011-03-24 2021-03-09 加利福尼亚理工学院 神经刺激器装置
JP5771437B2 (ja) * 2011-04-26 2015-08-26 学校法人同志社 生体装着用電極
EP2712491B1 (de) 2011-05-27 2019-12-04 Mc10, Inc. Flexible elektronische struktur
WO2013022853A1 (en) 2011-08-05 2013-02-14 Mc10, Inc. Catheter balloon methods and apparatus employing sensing elements
US9757050B2 (en) 2011-08-05 2017-09-12 Mc10, Inc. Catheter balloon employing force sensing elements
WO2013052180A2 (en) 2011-10-05 2013-04-11 University Of Kansas Methods and associated neural prosthetic devices for bridging brain areas to improve function
CA2864473C (en) 2011-11-11 2021-10-19 The Regents Of The University Of California Transcutaneous spinal cord stimulation: noninvasive tool for activation of locomotor circuitry
US10092750B2 (en) 2011-11-11 2018-10-09 Neuroenabling Technologies, Inc. Transcutaneous neuromodulation system and methods of using same
KR20140098780A (ko) 2011-11-11 2014-08-08 뉴로이네이블링 테크놀로지스, 인크. 운동, 감각, 자율적, 성적, 혈관운동 및 인식 기능의 복원을 가능하게 하기 위한 비침습성 신경조절 디바이스
US9226402B2 (en) 2012-06-11 2015-12-29 Mc10, Inc. Strain isolation structures for stretchable electronics
JP2015521894A (ja) 2012-07-05 2015-08-03 エムシー10 インコーポレイテッドMc10,Inc. 流量センシングを含むカテーテルデバイス
US9295842B2 (en) 2012-07-05 2016-03-29 Mc10, Inc. Catheter or guidewire device including flow sensing and use thereof
US9171794B2 (en) 2012-10-09 2015-10-27 Mc10, Inc. Embedding thin chips in polymer
JP2016500869A (ja) 2012-10-09 2016-01-14 エムシー10 インコーポレイテッドMc10,Inc. 衣類と一体化されたコンフォーマル電子回路
EP3878507A1 (de) 2013-03-15 2021-09-15 The Regents Of The University Of California Transkutane elektrische stimulation an mehreren stellen des rückenmarks zur bewegungserleichterung
US9919146B2 (en) 2013-05-01 2018-03-20 Sherwin Hua Methods and systems for intraventricular brain stimulation
US9706647B2 (en) 2013-05-14 2017-07-11 Mc10, Inc. Conformal electronics including nested serpentine interconnects
US9372123B2 (en) 2013-08-05 2016-06-21 Mc10, Inc. Flexible temperature sensor including conformable electronics
WO2015048563A2 (en) 2013-09-27 2015-04-02 The Regents Of The University Of California Engaging the cervical spinal cord circuitry to re-enable volitional control of hand function in tetraplegic subjects
JP2016532468A (ja) 2013-10-07 2016-10-20 エムシー10 インコーポレイテッドMc10,Inc. 検知および分析のためのコンフォーマルセンサシステム
US9949691B2 (en) 2013-11-22 2018-04-24 Mc10, Inc. Conformal sensor systems for sensing and analysis of cardiac activity
CN105874606B (zh) 2014-01-06 2021-01-12 Mc10股份有限公司 包封适形电子系统和器件及其制作和使用方法
US20150217120A1 (en) 2014-01-13 2015-08-06 Mandheerej Nandra Neuromodulation systems and methods of using same
EP3114911B1 (de) 2014-03-04 2023-05-03 Medidata Solutions, Inc. Flexibles mehrteiliges verkapselungsgehäuse für elektronische vorrichtungen
CA2952633C (en) 2014-06-20 2018-03-06 Velo3D, Inc. Apparatuses, systems and methods for three-dimensional printing
CA2958924C (en) 2014-08-21 2023-09-12 The Regents Of The University Of California Regulation of autonomic control of bladder voiding after a complete spinal cord injury
WO2016033369A1 (en) 2014-08-27 2016-03-03 The Regents Of The University Of California Multi-electrode array for spinal cord epidural stimulation
US9899330B2 (en) 2014-10-03 2018-02-20 Mc10, Inc. Flexible electronic circuits with embedded integrated circuit die
US10297572B2 (en) 2014-10-06 2019-05-21 Mc10, Inc. Discrete flexible interconnects for modules of integrated circuits
USD781270S1 (en) 2014-10-15 2017-03-14 Mc10, Inc. Electronic device having antenna
WO2016126795A1 (en) * 2015-02-03 2016-08-11 Children's Medical Center Corporation Detecting nerve damage using diffusion tensor imaging
EP3258837A4 (de) 2015-02-20 2018-10-10 Mc10, Inc. Automatische erkennung und konfiguration von am körper tragbaren vorrichtungen auf basis von status, position und/oder ausrichtung am körper
US10398343B2 (en) 2015-03-02 2019-09-03 Mc10, Inc. Perspiration sensor
WO2017015000A1 (en) 2015-07-17 2017-01-26 Mc10, Inc. Conductive stiffener, method of making a conductive stiffener, and conductive adhesive and encapsulation layers
WO2017031129A1 (en) 2015-08-19 2017-02-23 Mc10, Inc. Wearable heat flux devices and methods of use
WO2017035512A1 (en) 2015-08-26 2017-03-02 The Regents Of The University Of California Concerted use of noninvasive neuromodulation device with exoskeleton to enable voluntary movement and greater muscle activation when stepping in a chronically paralyzed subject
WO2017059215A1 (en) 2015-10-01 2017-04-06 Mc10, Inc. Method and system for interacting with a virtual environment
WO2017062508A1 (en) 2015-10-05 2017-04-13 Mc10, Inc. Method and System for Neuromodulation and Stimulation
US11097122B2 (en) 2015-11-04 2021-08-24 The Regents Of The University Of California Magnetic stimulation of the spinal cord to restore control of bladder and/or bowel
US10065270B2 (en) 2015-11-06 2018-09-04 Velo3D, Inc. Three-dimensional printing in real time
WO2017100695A1 (en) 2015-12-10 2017-06-15 Velo3D, Inc. Skillful three-dimensional printing
JP6979963B2 (ja) 2016-02-18 2021-12-15 ヴェロ・スリー・ディー・インコーポレイテッド 正確な3次元印刷
WO2017147053A1 (en) 2016-02-22 2017-08-31 Mc10, Inc. System, device, and method for coupled hub and sensor node on-body acquisition of sensor information
US10277386B2 (en) 2016-02-22 2019-04-30 Mc10, Inc. System, devices, and method for on-body data and power transmission
WO2017184705A1 (en) 2016-04-19 2017-10-26 Mc10, Inc. Method and system for measuring perspiration
WO2018005439A1 (en) 2016-06-29 2018-01-04 Velo3D, Inc. Three-dimensional printing and three-dimensional printers
US11691343B2 (en) 2016-06-29 2023-07-04 Velo3D, Inc. Three-dimensional printing and three-dimensional printers
US20210290949A1 (en) * 2016-07-28 2021-09-23 Galvani Bioelectronics Limited Nerve cuffs, methods of fabricating the same and methods of use
US10447347B2 (en) 2016-08-12 2019-10-15 Mc10, Inc. Wireless charger and high speed data off-loader
WO2018128695A2 (en) 2016-11-07 2018-07-12 Velo3D, Inc. Gas flow in three-dimensional printing
US20180186082A1 (en) 2017-01-05 2018-07-05 Velo3D, Inc. Optics in three-dimensional printing
US10315252B2 (en) 2017-03-02 2019-06-11 Velo3D, Inc. Three-dimensional printing of three-dimensional objects
US10449696B2 (en) 2017-03-28 2019-10-22 Velo3D, Inc. Material manipulation in three-dimensional printing
EP3974021B1 (de) 2017-06-30 2023-06-14 ONWARD Medical N.V. System zur neuromodulierung
US11407034B2 (en) 2017-07-06 2022-08-09 OmniTek Technology Ltda. Selective laser melting system and method of using same
US10272525B1 (en) 2017-12-27 2019-04-30 Velo3D, Inc. Three-dimensional printing systems and methods of their use
US10144176B1 (en) 2018-01-15 2018-12-04 Velo3D, Inc. Three-dimensional printing systems and methods of their use
EP3653260A1 (de) 2018-11-13 2020-05-20 GTX medical B.V. Sensor in bekleidung von gliedmassen oder schuhwerk
DE18205821T1 (de) 2018-11-13 2020-12-24 Gtx Medical B.V. Steuerungssystem zur bewegungsrekonstruktion und/oder wiederherstellung für einen patienten
EP3695878B1 (de) 2019-02-12 2023-04-19 ONWARD Medical N.V. System zur neuromodulierung
CN110694169A (zh) * 2019-09-16 2020-01-17 浙江大学 基于运动意图诱发中枢神经系统微电刺激的运动功能障碍神经桥接系统
DE19211698T1 (de) 2019-11-27 2021-09-02 Onward Medical B.V. Neuromodulation system
US20220331565A1 (en) * 2021-04-14 2022-10-20 The Board Of Trustees Of The University Of Arkansas Patient specific medical balloon forming machine and system

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5262945A (en) 1991-08-09 1993-11-16 The United States Of America As Represented By The Department Of Health And Human Services Method for quantification of brain volume from magnetic resonance images
US6176874B1 (en) 1993-10-18 2001-01-23 Masschusetts Institute Of Technology Vascularized tissue regeneration matrices formed by solid free form fabrication techniques
US6327491B1 (en) * 1998-07-06 2001-12-04 Neutar, Llc Customized surgical fixture
AU5692599A (en) * 1998-08-26 2000-03-21 Dow Chemical Company, The Internal mold release for low density reaction injection molded polyurethane foam
US20020187350A1 (en) 2001-01-29 2002-12-12 Honeywell International Inc. Robust highly reflective optical construction
US7072436B2 (en) 2001-08-24 2006-07-04 The Board Of Trustees Of The Leland Stanford Junior University Volumetric computed tomography (VCT)
US6734096B2 (en) * 2002-01-17 2004-05-11 International Business Machines Corporation Fine-pitch device lithography using a sacrificial hardmask
WO2003061537A1 (en) * 2002-01-17 2003-07-31 Masachusetts Eye And Ear Infirmary Minimally invasive retinal prosthesis
US7012266B2 (en) * 2002-08-23 2006-03-14 Samsung Electronics Co., Ltd. MEMS-based two-dimensional e-beam nano lithography device and method for making the same
US7369900B2 (en) * 2004-05-08 2008-05-06 Bojan Zdravkovic Neural bridge devices and methods for restoring and modulating neural activity

Also Published As

Publication number Publication date
EP1909890A2 (de) 2008-04-16
US20080208268A1 (en) 2008-08-28
WO2007003019A2 (en) 2007-01-11
JP4880681B2 (ja) 2012-02-22
US7991465B2 (en) 2011-08-02
ATE457773T1 (de) 2010-03-15
DK1909890T3 (da) 2010-05-03
EP1909890B1 (de) 2010-02-17
JP2008546491A (ja) 2008-12-25
WO2007003019A3 (en) 2007-03-01
CA2613694A1 (en) 2007-01-11

Similar Documents

Publication Publication Date Title
DE602006012327D1 (de) Mittel zur funktionalen wiederherstellung eines geschädigten nervensystems
WO2010018275A8 (es) Método y sistema de estimulación craneal multisitio
WO2010031056A3 (en) Methods and compositions for modulating ire1, src, and abl activity
DK1718756T3 (da) Botulinumtoksinscreeningassays
WO2007133718A3 (en) Non-invasive acquisition of large nerve action potentials (naps) with closely spaced surface electrodes and reduced stimulus artifacts
EP1993440A4 (de) Systeme und verfahren zur unterscheidung und/oder identifikation von durch darauf ausgerichtete nerven angeregten gewebebereichen zu diagnose- und/oder behandlungszwecken
WO2009069134A3 (en) Functional analysis of neurophysiological data
ATE429645T1 (de) Verwendung von eph-rezeptor-inhibitoren zur behandlung neurodegenerativer krankheiten
WO2006002262A3 (en) Genes and pathways differentially expressed in bipolar disorder and/or major depressive disorder
ATE513581T1 (de) Portabler applikator zur kollagenstimulation
WO2007095151A3 (en) Nerve regeneration employing keratin biomaterials
WO2010034015A3 (en) Modulating the alternative complement pathway
DE602005024335D1 (de) Implantierbarer Biosensor und Verfahren zur Überwachung der Herztätigkeit
WO2005074655A3 (en) Materials and method for promotion of nerve regeneration
DE602006010400D1 (de) Olanzapin-analoga und verfahren zu ihrer verwendung
WO2008027379A3 (en) Indicators of sirtuin activity and methods of use thereof
EP1898950A4 (de) Galk1s als modifikatoren des pten/akt-wegs und verwendungsverfahren
DE602007008365D1 (de) Verfahren zur steigerung der lymphatischen funktion
WO2006009947A3 (en) Migfs as modifiers of the igf pathway and methods of use
ATE543429T1 (de) Verfahren zur bestimmung des sympathikus-tonus und messsystem dafür
MXPA05011157A (es) Nuevo metodo para modular la actividad relacionada a los huesos.
ATE494551T1 (de) C20orf23 als modifikator des igfr-wegs und verwendungsverfahren
ATE487692T1 (de) Verfahren und verbindungen zum nachweis von medizinischen erkrankungen
WO2005072475A3 (en) Itpks as modifiers of the igfr pathway and methods of use
WO2006099185A3 (en) Brsk1s as modifiers of the pten/akt pathway and methods of use

Legal Events

Date Code Title Description
8364 No opposition during term of opposition