DE602005018702D1 - Reaktor mit Muldenplatte - Google Patents

Reaktor mit Muldenplatte

Info

Publication number
DE602005018702D1
DE602005018702D1 DE602005018702T DE602005018702T DE602005018702D1 DE 602005018702 D1 DE602005018702 D1 DE 602005018702D1 DE 602005018702 T DE602005018702 T DE 602005018702T DE 602005018702 T DE602005018702 T DE 602005018702T DE 602005018702 D1 DE602005018702 D1 DE 602005018702D1
Authority
DE
Germany
Prior art keywords
well
temperature
level
well plate
wells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602005018702T
Other languages
English (en)
Inventor
David L Klein
Gregory Andronaco
Stephen G Boyer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Molecular Devices LLC
Original Assignee
MICRORERACTOR TECHNOLOGIES Inc
MICRORERACTOR TECHNOLOGIES Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MICRORERACTOR TECHNOLOGIES Inc, MICRORERACTOR TECHNOLOGIES Inc filed Critical MICRORERACTOR TECHNOLOGIES Inc
Publication of DE602005018702D1 publication Critical patent/DE602005018702D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/12—Well or multiwell plates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/38—Caps; Covers; Plugs; Pouring means
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/26—Means for regulation, monitoring, measurement or control, e.g. flow regulation of pH
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/34—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of gas
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/14—Process control and prevention of errors
    • B01L2200/143—Quality control, feedback systems
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/046—Function or devices integrated in the closure
    • B01L2300/049—Valves integrated in closure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0663—Whole sensors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0829—Multi-well plates; Microtitration plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/10—Means to control humidity and/or other gases
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1822—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using Peltier elements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1827—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using resistive heater
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • B01L3/50851—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates specially adapted for heating or cooling samples
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • B01L3/50853—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates with covers or lids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/20—Oxygen containing
    • Y10T436/207497—Molecular oxygen
    • Y10T436/209163—Dissolved or trace oxygen or oxygen content of a sealed environment
DE602005018702T 2004-02-11 2005-02-10 Reaktor mit Muldenplatte Active DE602005018702D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10/777,581 US7374725B2 (en) 2004-02-11 2004-02-11 Well plate reactor

Publications (1)

Publication Number Publication Date
DE602005018702D1 true DE602005018702D1 (de) 2010-02-25

Family

ID=34827521

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005018702T Active DE602005018702D1 (de) 2004-02-11 2005-02-10 Reaktor mit Muldenplatte

Country Status (5)

Country Link
US (4) US7374725B2 (de)
EP (1) EP1579914B1 (de)
AT (1) ATE454216T1 (de)
DE (1) DE602005018702D1 (de)
DK (1) DK1579914T3 (de)

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CA2552717C (en) * 2004-01-07 2011-11-29 Levtech, Inc. Mixing bag with integral sparger and sensor receiver
US7374725B2 (en) * 2004-02-11 2008-05-20 Gener8, Inc. Well plate reactor
US20060030037A1 (en) * 2004-05-28 2006-02-09 Victor Joseph Thermo-controllable high-density chips for multiplex analyses
US20100261288A1 (en) * 2005-06-13 2010-10-14 Fortebio, Inc. Tip tray assembly for optical sensors
US7851204B2 (en) * 2006-06-09 2010-12-14 Pall Microreactor Technologies, Inc. Closure for milliliter scale bioreactor
MX2009001371A (es) * 2006-08-10 2009-04-22 Allen C Barnes Metodo y dispositivo de pruebas biologicas portatil.
US9550185B2 (en) * 2006-11-09 2017-01-24 Asmag-Holding Gmbh Titer plate with thin-film-light sensor
US8252581B2 (en) 2007-01-22 2012-08-28 Wafergen, Inc. Apparatus for high throughput chemical reactions
US7733488B1 (en) * 2007-01-26 2010-06-08 Revolution Optics, Llc Compact multi-wavelength optical reader and method of acquiring optical data on clustered assay samples using differing-wavelength light sources
DE202007002538U1 (de) * 2007-02-21 2007-06-06 Krebs, Torsten Begasungsvorrichtung und -system
WO2008106515A1 (en) * 2007-02-27 2008-09-04 The Board Of Trustees Of The University Of Illinois Insert device for multiwell plate
FR2916451A1 (fr) * 2007-05-25 2008-11-28 Mhs Ind Soc Par Actions Simpli Systeme de culture de cellules biologiques
WO2008157382A1 (en) * 2007-06-15 2008-12-24 Wyeth Methods for measuring ph in a small-scale cell culture system and predicting performance of cells in a large-scale culture system
US9192932B2 (en) * 2007-06-20 2015-11-24 Labcyte Inc. Closures which contain reservoirs and allow acoustic ejection
KR100822672B1 (ko) * 2007-06-27 2008-04-17 (주)실리콘화일 이미지센서를 이용한 진단장치 및 그 제조방법
DE102008001322A1 (de) * 2008-04-22 2009-10-29 Linos Photonics Gmbh & Co. Kg System zur optischen Analyse von Probenarrays
FR2934371B1 (fr) * 2008-07-25 2012-06-08 Nanotec Solution Dispositif capteur de biomasse a usage unique, procede de realisation de ce dispositif et bioreacteur a usage unique integrant ce capteur
WO2010125665A1 (ja) * 2009-04-30 2010-11-04 エイブル株式会社 リアクター
US20130189772A1 (en) * 2010-04-30 2013-07-25 Seemab Shaikh Multiwell-plate reactor and system therefor
MX342127B (es) * 2011-05-16 2016-09-14 Kirkstall Ltd Camara de bioreactor.
US20140329332A1 (en) * 2011-11-22 2014-11-06 Luxcel Biosciences Ltd. Device and method for rapid assay of multiple biological samples for oxygen consumption
BR112014019298A2 (pt) * 2012-02-04 2021-01-19 Douglas Scientific Método e aparelho para análise rápida, de alta sensibilidade, de amostras de baixo volume de materiais biológicos
CN103920551B (zh) * 2014-04-29 2015-09-16 中国人民解放军第三军医大学第三附属医院 玻璃电极存储装置
DK3259602T3 (da) 2015-02-20 2021-02-15 Takara Bio Usa Inc Fremgangsmåde til hurtig nøjagtig dispensering, visualisering og analyse af enkeltceller
WO2016168445A1 (en) 2015-04-17 2016-10-20 Pion Inc. Apparatus and method for the assessment of concentration profiling and permeability rates
US10240118B2 (en) * 2015-04-30 2019-03-26 Mark Langley System for monitoring growth media
US10935497B2 (en) * 2015-07-30 2021-03-02 Hitachi High-Tech Corporation Detection device for luminescence analysis and automated analyzer
US9952122B2 (en) * 2015-08-03 2018-04-24 Palo Alto Research Center Incorporated Polysensing bioelectronic test plate
EP3239285B1 (de) * 2016-04-27 2019-01-30 Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen Vorrichtung zur ermittlung und überwachung der physiologischen zustände von mikrobiellen kulturen in jedem einzelnen mikrobioreaktor einer mikrotiterplatte
WO2018017892A1 (en) 2016-07-21 2018-01-25 Takara Bio Usa, Inc. Multi-z imaging and dispensing with multi-well devices
JP6868242B2 (ja) * 2017-03-01 2021-05-12 クアーズテック株式会社 細胞培養モジュール
DE102017107033A1 (de) * 2017-03-31 2018-11-22 Presens Precision Sensing Gmbh Vorrichtung, verfahren und system zur parallelisierten erfassung mindestens einer veränderlichen während eines biologisch / chemischen prozesses
US11298701B2 (en) 2018-11-26 2022-04-12 King Instrumentation Technologies Microtiter plate mixing control system
EP4334428A1 (de) * 2021-05-07 2024-03-13 Beckman Coulter, Inc. Ph-kontrolle in parallelen kulturbohrlöchern

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EP1000345B1 (de) * 1997-08-01 2003-05-07 PreSens Precision Sensing GmbH Verfahren und vorrichtung zur referenzierung von fluoreszenzintensitätssignalen
DE69903800T2 (de) * 1998-03-18 2003-10-02 Massachusetts Inst Technology Vaskularisierte perfundierte anordnungen für mikrogewebe und mikroorgane
WO2002014539A1 (en) * 2000-08-14 2002-02-21 University Of Maryland Baltimore County Bioreactor and bioprocessing technique
US7070740B1 (en) 2000-09-28 2006-07-04 Beckman Coulter, Inc. Method and apparatus for processing biomolecule arrays
US6635441B2 (en) * 2001-02-08 2003-10-21 Irm, Llc Multi-sample fermentor and method of using same
US20040077075A1 (en) 2002-05-01 2004-04-22 Massachusetts Institute Of Technology Microfermentors for rapid screening and analysis of biochemical processes
US7211224B2 (en) * 2002-05-23 2007-05-01 Millipore Corporation One piece filtration plate
CA2391641A1 (fr) * 2002-06-28 2003-12-28 Robert Longin Plateforme robotisee de cultures cellulaires en batteries de reacteurs miniaturises, equipee d'un systeme de mesure en temps reel de la turbidite cellulaire ou toutes autres proprietes optiques
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Also Published As

Publication number Publication date
US20080131972A1 (en) 2008-06-05
US7713486B2 (en) 2010-05-11
US7887766B2 (en) 2011-02-15
US20080118403A1 (en) 2008-05-22
DK1579914T3 (da) 2010-03-29
EP1579914A3 (de) 2006-04-19
EP1579914B1 (de) 2010-01-06
EP1579914A2 (de) 2005-09-28
US7374725B2 (en) 2008-05-20
US7718134B2 (en) 2010-05-18
ATE454216T1 (de) 2010-01-15
US20100184199A1 (en) 2010-07-22
US20050176155A1 (en) 2005-08-11

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