DE60113095D1 - Oberflächen entmineralisiertes osteoimplantat und verfahren zu seiner herstellung - Google Patents

Oberflächen entmineralisiertes osteoimplantat und verfahren zu seiner herstellung

Info

Publication number
DE60113095D1
DE60113095D1 DE60113095T DE60113095T DE60113095D1 DE 60113095 D1 DE60113095 D1 DE 60113095D1 DE 60113095 T DE60113095 T DE 60113095T DE 60113095 T DE60113095 T DE 60113095T DE 60113095 D1 DE60113095 D1 DE 60113095D1
Authority
DE
Germany
Prior art keywords
entmineralized
plantate
production
eastern oil
eastern
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60113095T
Other languages
English (en)
Other versions
DE60113095T2 (de
Inventor
T Edwards
A Shimp
Michele Diegmann
M Boyce
L Scarborough
L Russell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Osteotech Inc
Original Assignee
Osteotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Osteotech Inc filed Critical Osteotech Inc
Application granted granted Critical
Publication of DE60113095D1 publication Critical patent/DE60113095D1/de
Publication of DE60113095T2 publication Critical patent/DE60113095T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3608Bone, e.g. demineralised bone matrix [DBM], bone powder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3641Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
    • A61L27/3645Connective tissue
    • A61L27/365Bones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/02Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
DE60113095T 2000-05-12 2001-05-14 Oberflächen entmineralisiertes osteoimplantat und verfahren zu seiner herstellung Expired - Lifetime DE60113095T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US20406900P 2000-05-12 2000-05-12
US204069P 2000-05-12
US22105600P 2000-07-27 2000-07-27
US221056P 2000-07-27
PCT/US2001/015599 WO2001087369A2 (en) 2000-05-12 2001-05-14 Osteoimplant and method for making same

Publications (2)

Publication Number Publication Date
DE60113095D1 true DE60113095D1 (de) 2005-10-06
DE60113095T2 DE60113095T2 (de) 2006-05-18

Family

ID=26899150

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60113095T Expired - Lifetime DE60113095T2 (de) 2000-05-12 2001-05-14 Oberflächen entmineralisiertes osteoimplantat und verfahren zu seiner herstellung

Country Status (7)

Country Link
US (2) US7179299B2 (de)
EP (1) EP1280564B1 (de)
AU (1) AU6158901A (de)
CA (1) CA2409479A1 (de)
DE (1) DE60113095T2 (de)
ES (1) ES2247113T3 (de)
WO (1) WO2001087369A2 (de)

Families Citing this family (85)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2438033A1 (en) * 2001-02-14 2002-08-22 Osteotech, Inc. Implant derived from bone
AU2002366381A1 (en) * 2001-12-18 2003-06-30 Ebi, L.P. Spinal implants
WO2003061653A1 (en) * 2002-01-22 2003-07-31 Pfizer Limited 3-(imidazolyl)-2-aminopropanoic acids for use as tafi-a inhibitors for the treatment of thrombotic diseases
US7744597B2 (en) 2002-06-26 2010-06-29 Lifenet Health Device and process for producing fiber products and fiber products produced thereby
JP2006501884A (ja) * 2002-08-12 2006-01-19 オステオテック,インコーポレイテッド 骨−ポリマー複合材料の合成
US20050251267A1 (en) * 2004-05-04 2005-11-10 John Winterbottom Cell permeable structural implant
EP1589962B1 (de) 2003-02-04 2015-04-08 Warsaw Orthopedic, Inc. Polyurethane für knochenimplantate
US7985414B2 (en) * 2003-02-04 2011-07-26 Warsaw Orthopedic, Inc. Polyurethanes for osteoimplants
WO2004084742A1 (en) * 2003-03-24 2004-10-07 Theken Surgical Llc Spinal implant adjustment device
US20050222687A1 (en) * 2004-04-02 2005-10-06 Gordana Vunjak-Novakovic Cartilage implant assembly and method for implantation
US7067123B2 (en) * 2003-04-29 2006-06-27 Musculoskeletal Transplant Foundation Glue for cartilage repair
US20050064042A1 (en) * 2003-04-29 2005-03-24 Musculoskeletal Transplant Foundation Cartilage implant plug with fibrin glue and method for implantation
US7494811B2 (en) * 2003-05-01 2009-02-24 Lifenet Health In vitro growth of tissues suitable to the formation of bone and bone forming tissue formed thereby
US7901457B2 (en) * 2003-05-16 2011-03-08 Musculoskeletal Transplant Foundation Cartilage allograft plug
US7488348B2 (en) * 2003-05-16 2009-02-10 Musculoskeletal Transplant Foundation Cartilage allograft plug
US20090291112A1 (en) * 2003-05-16 2009-11-26 Truncale Katherine G Allograft osteochondral plug combined with cartilage particle mixture
EP1701672A4 (de) * 2003-12-19 2011-04-27 Osteotech Inc Aus gewebe erhaltenes maschengeflecht für die orthopädische regeneration
EP1701729B1 (de) * 2003-12-31 2018-05-02 Warsaw Orthopedic, Inc. Verbesserte knochenmatrixzusammensetzungen und verfahren
US20070231788A1 (en) * 2003-12-31 2007-10-04 Keyvan Behnam Method for In Vitro Assay of Demineralized Bone Matrix
US8012210B2 (en) * 2004-01-16 2011-09-06 Warsaw Orthopedic, Inc. Implant frames for use with settable materials and related methods of use
US20060015184A1 (en) * 2004-01-30 2006-01-19 John Winterbottom Stacking implants for spinal fusion
WO2005097004A2 (en) * 2004-03-26 2005-10-20 Synthes (U.S.A.) Allograft implant
US8697139B2 (en) 2004-09-21 2014-04-15 Frank M. Phillips Method of intervertebral disc treatment using articular chondrocyte cells
US7837740B2 (en) 2007-01-24 2010-11-23 Musculoskeletal Transplant Foundation Two piece cancellous construct for cartilage repair
US20080220044A1 (en) * 2007-03-06 2008-09-11 Semler Eric J Cancellous construct with support ring for repair of osteochondral defects
EP1819375A2 (de) 2004-12-08 2007-08-22 Interpore Spine Ltd. Komposit mit kontinuierlicher phase für die muskel-skelett-reparatur
US20070038303A1 (en) * 2006-08-15 2007-02-15 Ebi, L.P. Foot/ankle implant and associated method
US8535357B2 (en) 2004-12-09 2013-09-17 Biomet Sports Medicine, Llc Continuous phase compositions for ACL repair
AU2006236548A1 (en) 2005-04-15 2006-10-26 Musculoskeletal Transplant Foundation Vertebral disc repair
US7815926B2 (en) * 2005-07-11 2010-10-19 Musculoskeletal Transplant Foundation Implant for articular cartilage repair
EP1926459B1 (de) 2005-09-19 2015-01-07 Histogenics Corporation Zellunterstützende matrix mit eng definierter, gleichmässig senkrecht und nicht zufällig organisierter porosität und porendichte und verfahren zur herstellung davon
CA2627907C (en) 2005-11-01 2014-06-17 Osteotech, Inc. Osteoinductive composition comprising osteoinductive factors recovered from mineralized bone and a carrier
US20070162132A1 (en) 2005-12-23 2007-07-12 Dominique Messerli Flexible elongated chain implant and method of supporting body tissue with same
AU2007207495A1 (en) 2006-01-19 2007-07-26 Warsaw Orthopedic, Inc. Porous osteoimplant
CA2637616A1 (en) * 2006-01-19 2007-07-26 Osteotech, Inc. Injectable and moldable bone substitute materials
EP2076220A2 (de) 2006-07-25 2009-07-08 Musculoskeletal Transplant Foundation Verkapselte entmineralisierte spongiosagewebeformen für bandscheibenkernaugmentation, wiederherstellung oder ersatz sowie implantierverfahren
US8435551B2 (en) * 2007-03-06 2013-05-07 Musculoskeletal Transplant Foundation Cancellous construct with support ring for repair of osteochondral defects
US20080294270A1 (en) * 2007-05-24 2008-11-27 Zimmer Orthobiologics, Inc. Differentially processed tissue and processing methods thereof
US9554920B2 (en) 2007-06-15 2017-01-31 Warsaw Orthopedic, Inc. Bone matrix compositions having nanoscale textured surfaces
CA2690457C (en) 2007-06-15 2018-02-20 Osteotech, Inc. Bone matrix compositions and methods
WO2008157492A2 (en) 2007-06-15 2008-12-24 Osteotech, Inc. Osteoinductive demineralized cancellous bone
AU2008265852B2 (en) 2007-06-15 2014-04-17 Warsaw Orthopedic, Inc. Method of treating tissue
US9358113B2 (en) * 2007-07-10 2016-06-07 Warsaw Orthopedic, Inc. Delivery system
US20110054408A1 (en) * 2007-07-10 2011-03-03 Guobao Wei Delivery systems, devices, tools, and methods of use
US9138509B2 (en) * 2007-09-14 2015-09-22 Musculoskeletal Transplant Foundation Composition for filling bone defects
ES2446544T3 (es) * 2007-10-19 2014-03-10 Warsaw Orthopedic, Inc. Composiciones de matrices óseas desmineralizadas y métodos
EP2224884A2 (de) * 2007-12-05 2010-09-08 Musculoskeletal Transplant Foundation Spongiosa-implantat zur knorpelreparatur
WO2009111069A1 (en) 2008-03-05 2009-09-11 Musculoskeletal Transplant Foundation Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles
US8333804B1 (en) 2008-03-27 2012-12-18 Spinelogik, Inc. Intervertebral fusion device and method of use
US8313528B1 (en) 2008-03-27 2012-11-20 Spinelogik, Inc. Intervertebral fusion device and method of use
CN102036612B (zh) * 2008-03-28 2014-08-06 骨科技术公司 用于整形外科应用的骨锚
WO2012134540A2 (en) 2010-10-22 2012-10-04 Vanderbilt University Injectable synthetic pur composite
CA2745038A1 (en) * 2008-10-30 2010-05-27 Osteotech, Inc. Bone/polyurethane composites and methods thereof
US20100274355A1 (en) * 2009-01-21 2010-10-28 Mcguire David A Bone-tendon-bone assembly with cancellous allograft bone block having cortical end portion
WO2010093950A1 (en) 2009-02-12 2010-08-19 Osteotech, Inc. Delivery system cartridge
US9427324B1 (en) * 2010-02-22 2016-08-30 Spinelogik, Inc. Intervertebral fusion device and method of use
US10130736B1 (en) 2010-05-14 2018-11-20 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US9352003B1 (en) 2010-05-14 2016-05-31 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US8343229B2 (en) 2010-07-16 2013-01-01 Ebi, Llc Textured bone block implants
US8435305B2 (en) 2010-08-31 2013-05-07 Zimmer, Inc. Osteochondral graft delivery device and uses thereof
US9358122B2 (en) 2011-01-07 2016-06-07 K2M, Inc. Interbody spacer
US9149365B2 (en) 2013-03-05 2015-10-06 Globus Medical, Inc. Low profile plate
US9539109B2 (en) 2011-09-16 2017-01-10 Globus Medical, Inc. Low profile plate
US10881526B2 (en) 2011-09-16 2021-01-05 Globus Medical, Inc. Low profile plate
US9848994B2 (en) 2011-09-16 2017-12-26 Globus Medical, Inc. Low profile plate
US9770340B2 (en) 2011-09-16 2017-09-26 Globus Medical, Inc. Multi-piece intervertebral implants
US8961606B2 (en) 2011-09-16 2015-02-24 Globus Medical, Inc. Multi-piece intervertebral implants
US9204975B2 (en) 2011-09-16 2015-12-08 Globus Medical, Inc. Multi-piece intervertebral implants
US9398960B2 (en) 2011-09-16 2016-07-26 Globus Medical, Inc. Multi-piece intervertebral implants
US9681959B2 (en) 2011-09-16 2017-06-20 Globus Medical, Inc. Low profile plate
US10245155B2 (en) 2011-09-16 2019-04-02 Globus Medical, Inc. Low profile plate
US9237957B2 (en) 2011-09-16 2016-01-19 Globus Medical, Inc. Low profile plate
US9554914B2 (en) * 2011-12-12 2017-01-31 Wright Medical Technology, Inc. Fusion implant
US9968455B2 (en) * 2012-04-27 2018-05-15 Howmedica Osteonics Corp. Multiple component bone void filling implant
US9585764B2 (en) * 2012-07-26 2017-03-07 Warsaw Orthopedic, Inc. Bone implant device
US9345589B2 (en) * 2013-12-19 2016-05-24 Ilion Medical, Inc. Bone implants for orthopedic procedures and corresponding methods
US20150366668A1 (en) * 2014-06-23 2015-12-24 Community Blood Center Cellular-scale surface modification for increased osteogenic protein expression
US10077420B2 (en) 2014-12-02 2018-09-18 Histogenics Corporation Cell and tissue culture container
WO2016187413A1 (en) 2015-05-21 2016-11-24 Musculoskeletal Transplant Foundation Modified demineralized cortical bone fibers
US20170312079A1 (en) * 2016-04-28 2017-11-02 Warsaw Orthopedic, Inc. Mechanically entangled demineralized bone fibers
CN109923947B (zh) * 2016-11-09 2022-04-05 昭和电工材料株式会社 印刷线路板及半导体封装体
US11452608B2 (en) 2017-04-05 2022-09-27 Globus Medical, Inc. Decoupled spacer and plate and method of installing the same
US10376385B2 (en) 2017-04-05 2019-08-13 Globus Medical, Inc. Decoupled spacer and plate and method of installing the same
WO2021076245A1 (en) 2019-10-18 2021-04-22 Sparta Biopharma LLC Connective tissue to bone interface scaffolds
US20230364304A1 (en) 2020-08-24 2023-11-16 Sparta Biopharma LLC Methods of forming bone interface scaffolds

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5061286A (en) * 1989-08-18 1991-10-29 Osteotech, Inc. Osteoprosthetic implant
US5290558A (en) * 1989-09-21 1994-03-01 Osteotech, Inc. Flowable demineralized bone powder composition and its use in bone repair
US6652592B1 (en) * 1997-10-27 2003-11-25 Regeneration Technologies, Inc. Segmentally demineralized bone implant
US6090998A (en) * 1997-10-27 2000-07-18 University Of Florida Segmentally demineralized bone implant
US5899939A (en) * 1998-01-21 1999-05-04 Osteotech, Inc. Bone-derived implant for load-supporting applications
US6123731A (en) * 1998-02-06 2000-09-26 Osteotech, Inc. Osteoimplant and method for its manufacture
US6458375B1 (en) * 1998-02-27 2002-10-01 Musculoskeletal Transplant Foundation Malleable paste with allograft bone reinforcement for filling bone defects
US6200347B1 (en) * 1999-01-05 2001-03-13 Lifenet Composite bone graft, method of making and using same
US6206923B1 (en) * 1999-01-08 2001-03-27 Sdgi Holdings, Inc. Flexible implant using partially demineralized bone
US6277149B1 (en) * 1999-06-08 2001-08-21 Osteotech, Inc. Ramp-shaped intervertebral implant
US6436101B1 (en) * 1999-10-13 2002-08-20 James S. Hamada Rasp for use in spine surgery
US6340477B1 (en) * 2000-04-27 2002-01-22 Lifenet Bone matrix composition and methods for making and using same
US6638310B2 (en) * 2000-07-26 2003-10-28 Osteotech, Inc. Intervertebral spacer and implant insertion instrumentation
US6652593B2 (en) * 2001-02-28 2003-11-25 Synthes (Usa) Demineralized bone implants
AU2002340306A1 (en) * 2001-10-30 2003-05-12 Osteotech, Inc. Bone implant and insertion tools

Also Published As

Publication number Publication date
DE60113095T2 (de) 2006-05-18
US20030144743A1 (en) 2003-07-31
WO2001087369A3 (en) 2002-07-04
EP1280564B1 (de) 2005-08-31
ES2247113T3 (es) 2006-03-01
AU6158901A (en) 2001-11-26
US7662184B2 (en) 2010-02-16
EP1280564A2 (de) 2003-02-05
WO2001087369A2 (en) 2001-11-22
US20070168030A1 (en) 2007-07-19
CA2409479A1 (en) 2001-11-22
US7179299B2 (en) 2007-02-20

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