DE60028352D1 - Instrument zur herstellung von gewebe-arrays - Google Patents

Instrument zur herstellung von gewebe-arrays

Info

Publication number
DE60028352D1
DE60028352D1 DE60028352T DE60028352T DE60028352D1 DE 60028352 D1 DE60028352 D1 DE 60028352D1 DE 60028352 T DE60028352 T DE 60028352T DE 60028352 T DE60028352 T DE 60028352T DE 60028352 D1 DE60028352 D1 DE 60028352D1
Authority
DE
Germany
Prior art keywords
punch
instrument
platform
tissue arrays
punch platform
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60028352T
Other languages
English (en)
Other versions
DE60028352T2 (de
Inventor
B Leighton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BEECHER INSTR SILVER SPRINGS
Original Assignee
BEECHER INSTR SILVER SPRINGS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23001219&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60028352(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by BEECHER INSTR SILVER SPRINGS filed Critical BEECHER INSTR SILVER SPRINGS
Application granted granted Critical
Publication of DE60028352D1 publication Critical patent/DE60028352D1/de
Publication of DE60028352T2 publication Critical patent/DE60028352T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
    • G01N2001/2873—Cutting or cleaving
    • G01N2001/288—Filter punches
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/36—Embedding or analogous mounting of samples
    • G01N2001/368—Mounting multiple samples in one block, e.g. TMA [Tissue Microarrays]
DE60028352T 1999-03-05 2000-03-06 Instrument zur herstellung von gewebe-arrays Expired - Fee Related DE60028352T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US263304 1999-03-05
US09/263,304 US6103518A (en) 1999-03-05 1999-03-05 Instrument for constructing tissue arrays
PCT/US2000/005824 WO2000052132A1 (en) 1999-03-05 2000-03-06 Instrument for constructing tissue arrays

Publications (2)

Publication Number Publication Date
DE60028352D1 true DE60028352D1 (de) 2006-07-06
DE60028352T2 DE60028352T2 (de) 2007-03-29

Family

ID=23001219

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60028352T Expired - Fee Related DE60028352T2 (de) 1999-03-05 2000-03-06 Instrument zur herstellung von gewebe-arrays

Country Status (15)

Country Link
US (1) US6103518A (de)
EP (1) EP1161520B1 (de)
JP (1) JP2002537794A (de)
KR (1) KR100637036B1 (de)
CN (1) CN1255527C (de)
AT (1) ATE328064T1 (de)
AU (2) AU3709400A (de)
CA (1) CA2364458C (de)
DE (1) DE60028352T2 (de)
DK (1) DK1161520T3 (de)
ES (1) ES2262513T3 (de)
IL (1) IL145198A0 (de)
NZ (1) NZ514394A (de)
PT (1) PT1161520E (de)
WO (2) WO2000051812A1 (de)

Families Citing this family (97)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7285422B1 (en) 1997-01-23 2007-10-23 Sequenom, Inc. Systems and methods for preparing and analyzing low volume analyte array elements
US6699710B1 (en) * 1998-02-25 2004-03-02 The United States Of America As Represented By The Department Of Health And Human Services Tumor tissue microarrays for rapid molecular profiling
US20090111101A1 (en) * 1998-05-09 2009-04-30 Ikonisys, Inc. Automated Cancer Diagnostic Methods Using FISH
US6713309B1 (en) 1999-07-30 2004-03-30 Large Scale Proteomics Corporation Microarrays and their manufacture
JP2003510571A (ja) * 1999-09-24 2003-03-18 ジョナサン コヘン 組織試料中の分子標的の臨床的有用性を評価するための高処理量システム
WO2001031317A1 (en) * 1999-10-26 2001-05-03 Genometrix Genomics Incorporated Method and apparatus for selectively retrieving biological samples for processing
WO2001031333A1 (en) * 1999-10-26 2001-05-03 Genometrix Genomics Incorporated Process for requesting biological experiments and for the delivery of experimental information
DE10001136C2 (de) * 2000-01-13 2003-09-04 Michael Mengel Verfahren zur Herstellung von Materialblöcken mit multiplen Untersuchungsproben
WO2001098525A2 (en) * 2000-06-22 2001-12-27 Clinomics Laboratories, Inc. Frozen tissue microarrays and methods for using the same
US6890760B1 (en) * 2000-07-31 2005-05-10 Agilent Technologies, Inc. Array fabrication
CN1261745C (zh) 2000-08-15 2006-06-28 拜澳富斯毫微科学有限公司 纳米级分子阵列排布机
US20020168639A1 (en) * 2000-09-22 2002-11-14 Muraca Patrick J. Profile array substrates
WO2002055199A2 (en) 2000-10-30 2002-07-18 Sequenom Inc Method and apparatus for delivery of submicroliter volumes onto a substrate
WO2003050509A1 (en) * 2000-11-30 2003-06-19 Instrumedics Inc. A method for creating a frozen tissue array
US7027633B2 (en) * 2000-11-30 2006-04-11 Foran David J Collaborative diagnostic systems
US7171030B2 (en) * 2000-11-30 2007-01-30 University Of Medicine & Denistry Of New Jersey Systems for analyzing microtissue arrays
US7079673B2 (en) * 2002-02-05 2006-07-18 University Of Medicine & Denistry Of Nj Systems for analyzing microtissue arrays
US20030215936A1 (en) * 2000-12-13 2003-11-20 Olli Kallioniemi High-throughput tissue microarray technology and applications
US20040085443A1 (en) * 2000-12-13 2004-05-06 Kallioniemi Olli P Method and system for processing regions of interest for objects comprising biological material
US6416719B1 (en) * 2001-01-19 2002-07-09 Gilson, Inc. Plate locator for precision liquid handler
US6474181B2 (en) * 2001-01-24 2002-11-05 Gilson, Inc. Probe tip alignment for precision liquid handler
US6716619B1 (en) 2001-02-08 2004-04-06 Clinomics Biosciences, Inc. Stylet for use with tissue microarrayer and molds
US6534307B1 (en) 2001-02-08 2003-03-18 Clinomics Biosciences, Inc. Frozen tissue microarrayer
US20020150966A1 (en) * 2001-02-09 2002-10-17 Muraca Patrick J. Specimen-linked database
US6383801B1 (en) * 2001-03-19 2002-05-07 Beecher Instruments Double z-drive tissue array instrument
US6468783B1 (en) * 2001-04-09 2002-10-22 Beecher Instruments Punch-changing tissue array instrument
ES2298409T3 (es) * 2001-03-19 2008-05-16 Beecher Instruments Instrumento para la creacion de series de tejido.
US20020182647A1 (en) * 2001-04-30 2002-12-05 Emmert-Buck Michael R. Histoscreen method
US20030017446A1 (en) * 2001-07-20 2003-01-23 Ardais Corporation Instruments and methods for creating a tissue microarray
US6696271B2 (en) 2001-08-23 2004-02-24 The Regents Of The University Of California Frozen tissue microarray technology for analysis of RNA, DNA, and proteins
DE10147950C2 (de) * 2001-09-28 2003-12-04 Olympus Biosystems Gmbh Verfahren und Vorrichtung zur Extraktion von Zellmaterial aus einer Gewebeprobe
US20030087455A1 (en) * 2001-11-07 2003-05-08 Eggers Mitchell D Sample carrier system
US20030087425A1 (en) * 2001-11-07 2003-05-08 Eggers Mitchell D Sample carrier
US20030129755A1 (en) * 2001-11-07 2003-07-10 Genvault Corporation System and method of storing and retrieving storage elements
US7584240B2 (en) * 2001-11-07 2009-09-01 Genvault Corporation Automated biological sample archive for storage, retrieval and analysis of large numbers of samples for remote clients
US7142987B2 (en) * 2001-11-07 2006-11-28 Genvault Corporation Apparatus, system, and method of archival and retrieval of samples
US20030166274A1 (en) * 2001-11-15 2003-09-04 Hewitt Charles W. Three-dimensional matrix for producing living tissue equivalents
IL161976A0 (en) * 2001-11-20 2005-11-20 Genentech Inc Cell and tissue arrays and microarrays and methodsof use
US20040197897A1 (en) * 2002-03-19 2004-10-07 Leighton Stephen B. Tissue array instrument
US20030186353A1 (en) * 2002-04-02 2003-10-02 Page Erickson Microscopic precision construction of tissue array block
US20040126837A1 (en) * 2002-05-23 2004-07-01 Matthew Baker Pseudo-tissues and uses thereof
US20050037406A1 (en) * 2002-06-12 2005-02-17 De La Torre-Bueno Jose Methods and apparatus for analysis of a biological specimen
US7272252B2 (en) * 2002-06-12 2007-09-18 Clarient, Inc. Automated system for combining bright field and fluorescent microscopy
HU2464U (en) * 2002-06-25 2003-03-28 Szekeres Gyoergy Dr Hand instrument set for constructing tissue array
WO2004021248A2 (en) * 2002-08-28 2004-03-11 Applera Corporation Automated framework for the analysis of biological data
DE10239739B4 (de) * 2002-08-29 2006-05-11 Leica Mikrosysteme Gmbh Vorrichtung und Verfahren zur Durchführung von immunologischen Markierungstechniken für Gewebedünnschnitte
AT412239B (de) * 2002-10-31 2004-11-25 Oridis Biomed Forschungs Und E Verfahren und vorrichtung zur manipulation mit proben
AT412238B (de) * 2002-10-31 2004-11-25 Oridis Biomed Forschungs Und E Verfahren und vorrichtung zur manipulation mit proben
US7718442B2 (en) * 2002-11-22 2010-05-18 Genvault Corporation Sealed sample storage element system and method
US20100075858A1 (en) * 2003-04-29 2010-03-25 Genvault Corporation Biological bar code
WO2005040348A2 (en) * 2003-10-23 2005-05-06 Georgetown University Method for two- and three-dimensional microassembly of patterns and structures
DK2322278T3 (en) * 2003-10-24 2017-04-10 Aushon Biosystems Inc Apparatus and method for dispensing liquid, semi-solid and solid samples
DE602005016402D1 (de) * 2004-05-24 2009-10-15 Genvault Corp Stabile lagerung von protein und stabile lagerung von nukleinsäure in wiedergewinnbarer form
EP2444788A3 (de) 2004-06-18 2012-08-22 Covance, Inc. Feuchtigkeitsbarriere für einen Mikroarrayer
US20060041385A1 (en) * 2004-08-18 2006-02-23 Bauer Kenneth D Method of quantitating proteins and genes in cells using a combination of immunohistochemistry and in situ hybridization
US7854899B2 (en) * 2004-08-26 2010-12-21 The United States Of America As Represented By The Secretary Of Health And Human Services Template methods and devices for preparing sample arrays
CN101061383B (zh) * 2004-11-24 2012-08-22 李荣山 细胞块的制备方法
FR2878859B1 (fr) 2004-12-02 2007-03-23 Alphelys Sarl Dispositif de prelevement de carottes pour tissue array
DE102005005518A1 (de) * 2005-02-01 2006-08-10 Eberhard-Karls-Universität Tübingen Universitätsklinikum Einführvorrichtung für biologische Proben
US20060178833A1 (en) * 2005-02-04 2006-08-10 Bauer Kenneth D System for and method of providing diagnostic information through microscopic imaging
US7405056B2 (en) * 2005-03-02 2008-07-29 Edward Lam Tissue punch and tissue sample labeling methods and devices for microarray preparation, archiving and documentation
US7618809B2 (en) * 2005-03-23 2009-11-17 Gebing Ronald A Microarrayer with coaxial multiple punches
US20060269985A1 (en) * 2005-05-31 2006-11-30 Yasuhiko Kitayama Method for constructing array blocks, and tissue punching instrument and tissue blocks used therefor
US20070042340A1 (en) * 2005-08-19 2007-02-22 Juha Kononen Method and apparatus for protecting biological specimens
DE102005041782A1 (de) * 2005-09-01 2007-03-08 Leica Microsystems Nussloch Gmbh Vorrichtung zur Herstellung von Gewebearrays
DE102005041780A1 (de) * 2005-09-01 2007-03-08 Leica Microsystems Nussloch Gmbh Vorrichtung zur Herstellung von Gewebearrays
US7597846B2 (en) * 2005-09-01 2009-10-06 Leica Biosystems Nussloch Gmbh Apparatus for producing tissue arrays
DE102005041781A1 (de) * 2005-09-01 2007-03-08 Leica Microsystems Nussloch Gmbh Vorrichtung zur Herstellung von Gewebearrays
US20070091109A1 (en) * 2005-09-13 2007-04-26 Roscoe Atkinson Image quality
WO2007035984A1 (en) * 2005-09-29 2007-04-05 Oryx Holdings Pty Ltd Method and device for collection and transport of a biological sample
US20070251438A1 (en) * 2006-04-28 2007-11-01 Cheng Tien Int'l Corp. Adjustable punching device
WO2007149311A2 (en) * 2006-06-16 2007-12-27 Promega Corporation Biological sample processing apparatus
WO2008153879A1 (en) 2007-06-08 2008-12-18 Regan Spencer Fulton Method and apparatus for producing high-yield tissue microarray blocks
WO2009008843A1 (en) * 2007-07-10 2009-01-15 National University Of Singapore Apparatus for forming a tissue array
KR100816816B1 (ko) * 2007-09-14 2008-03-26 유니트마 주식회사 자동 조직미세배열 장치 및 그에 따른 제조방법
US20090180931A1 (en) 2007-09-17 2009-07-16 Sequenom, Inc. Integrated robotic sample transfer device
US7980148B2 (en) * 2007-11-30 2011-07-19 Syngenta Participations Ag Device for sampling plant material
WO2009155612A2 (en) * 2008-06-20 2009-12-23 Genvault Corporation Sample collection and storage devices and methods of use thereof
JP2012501681A (ja) * 2008-09-12 2012-01-26 ジェンボールト コーポレイション 生体分子の貯蔵および安定化のためのマトリックスおよび媒体
ES2321154B1 (es) * 2009-01-19 2010-01-25 Grifols, S.A. Dispositivo para la extraccion automatica de muestras de liquido de recipientes colectores y procedimiento para realizar dicha extraccion.
JP5652769B2 (ja) * 2009-10-30 2015-01-14 株式会社パソロジー研究所 組織アレイの製造装置
US8437874B2 (en) * 2010-02-26 2013-05-07 Syngenta Participations Ag Transfer station for plant material sampling and tracking system
JP5761732B2 (ja) * 2010-07-29 2015-08-12 サクラ精機株式会社 組織アレイの組織片形成方法及び組織アレイの組織片形成装置
DE102011075039A1 (de) 2011-04-29 2012-10-31 Hamilton Bonaduz Ag Stanzvorrichtung mit beleuchteter Aufnahmeplatte
DE102011075036A1 (de) 2011-04-29 2012-10-31 Hamilton Bonaduz Ag Stanzvorrichtung mit Greifeinheit
DE102011075037A1 (de) * 2011-04-29 2012-10-31 Hamilton Bonaduz Ag Stanzvorrichtung mit Aufnahmeplatte
DE102011075035A1 (de) * 2011-04-29 2012-10-31 Hamilton Bonaduz Ag Stanzvorrichtung mit modularem Stanzmittel
US9134202B2 (en) * 2012-01-26 2015-09-15 Cryoxtract Instruments, Llc Robotic end effector for frozen aliquotter and methods of taking a frozen aliquot from biological samples
CN104583754A (zh) 2012-06-22 2015-04-29 莱卡生物系统努斯洛赫有限责任公司 组织样本容器和方法
EP2864467B1 (de) 2012-06-22 2019-04-03 Leica Biosystems Nussloch GmbH Vorrichtung zum transport von biopsiegewebeproben
US9097629B2 (en) 2013-03-15 2015-08-04 Leica Biosystems Nussloch Gmbh Tissue cassette with retractable member
CA2845832C (en) 2013-03-15 2020-09-22 Leica Biosystems Nussloch Gmbh Tissue cassette with biasing element
US9052256B2 (en) 2013-03-15 2015-06-09 Leica Biosystems Nussloch Gmbh Method for processing and embedding tissue
JP6406005B2 (ja) * 2014-05-29 2018-10-17 三星ダイヤモンド工業株式会社 ツールホルダ及び溝加工装置
US11300486B1 (en) 2016-11-23 2022-04-12 Array Science, Llc Apparatus for producing high yield cores for use in a microarray block, method for using same
CN111073808B (zh) * 2020-03-03 2023-06-30 上海汇像信息技术有限公司 微生物检测培养皿涂布装置及涂布控制方法
EP4261522A1 (de) 2022-04-11 2023-10-18 Array Science, LLC Verfahren zur herstellung von kernen mit hoher ausbeute zur verwendung in einem mikroarrayblock

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2563343B1 (fr) * 1984-04-19 1986-06-13 Rhone Poulenc Sante Dispositif pour effectuer des prelevements dans des milieux semi-solides
US4979093A (en) * 1987-07-16 1990-12-18 Cavro Scientific Instruments XYZ positioner
US5355304A (en) * 1990-01-30 1994-10-11 Demoranville Victoria E Clinical laboratory work-flow system which semi-automates validated immunoassay and electrophoresis protocols
US5355439A (en) * 1991-08-05 1994-10-11 Bio Tek Instruments Method and apparatus for automated tissue assay
US5439649A (en) * 1993-09-29 1995-08-08 Biogenex Laboratories Automated staining apparatus
KR200327028Y1 (ko) * 2003-06-17 2003-09-19 장시창 인체조직검사기구

Also Published As

Publication number Publication date
KR100637036B1 (ko) 2006-10-20
PT1161520E (pt) 2006-07-31
AU753107B2 (en) 2002-10-10
CN1255527C (zh) 2006-05-10
DK1161520T3 (da) 2006-09-25
EP1161520A4 (de) 2004-11-24
EP1161520B1 (de) 2006-05-31
CA2364458A1 (en) 2000-09-08
AU3709400A (en) 2000-09-21
IL145198A0 (en) 2002-06-30
ES2262513T3 (es) 2006-12-01
ATE328064T1 (de) 2006-06-15
CA2364458C (en) 2009-06-02
EP1161520A1 (de) 2001-12-12
WO2000051812A1 (en) 2000-09-08
US6103518A (en) 2000-08-15
CN1347448A (zh) 2002-05-01
DE60028352T2 (de) 2007-03-29
WO2000052132A1 (en) 2000-09-08
NZ514394A (en) 2002-07-26
AU3726900A (en) 2000-09-21
KR20020010579A (ko) 2002-02-04
JP2002537794A (ja) 2002-11-12

Similar Documents

Publication Publication Date Title
DE60028352D1 (de) Instrument zur herstellung von gewebe-arrays
EP1752783A3 (de) Funkortungssystem
DE60141119D1 (de) Verfahren zur laserabscheidung
DE69017419T2 (de) Verfahren zur Herstellung einer Biegeeinrichtung, insbesondere für ein Endoskop oder einen chirurgischen Katheter.
EP1715384A3 (de) Lithografische Vorrichtung und Positionierungsvorrichtung
DE68900228D1 (de) Implantat fuer eine vorrichtung zur rueckgratsosteosynthese, insbesondere fuer die unfallchirurgie.
DE69019509T2 (de) Vorrichtung zur Positionierung einer Elektrode.
DE58907254D1 (de) Vorrichtung zur transösophagealen echokardiographie.
EP1672430A3 (de) Lithografische Vorrichtung, Analyseplatte, Baugruppe, Verfahren zur Messung eines Parameters eines Projektionssystems und Strukturierungsmittel
GB0321742D0 (en) Producing a logarithmic signal approximation with vairable precision
DE50007326D1 (de) Verfahren zur herstellung mikromechanischer strukturen
EP1508726A3 (de) Schalthebel
DE60100220D1 (de) Vorrichtung zur Herstellung eines Stanzmessers
DE69006942D1 (de) Schiefscheibenverdichter mit einer Vorrichtung zur Hubveränderung.
EP1582908A3 (de) Messgerät und Verfahren
EP1323484A3 (de) Metallrohr und Verfahren zu seiner Herstellung
US5862729A (en) Mechanical punch apparatus and method of using same
DK1370639T3 (da) Instrument til frembringelse af vævsarrays
EP1837705A3 (de) Lithografische Vorrichtung und Herstellungsverfahren dafür
DE69014680T2 (de) Einrichtung zur Stimmensynthese.
EP1486829A3 (de) Trägerplattensystem, Belichtungsanlage und Verfahren zur Herstellung einer Vorrichtung
EP1077361A3 (de) Verfahren und Vorrichtung zur Koördinatenmessung an einem Turbinenschaufel
EP1447863A3 (de) Ätzmaske
DE58902956D1 (de) Vorrichtung zur hubverstellung einer stanzpresse.
IT1311986B1 (it) Procedimento per la preparazione di monoesteri nitrici di compostidiidrossialchilici e diidrossicicloalchilici.

Legal Events

Date Code Title Description
8363 Opposition against the patent
8339 Ceased/non-payment of the annual fee