DE60027542D1 - Methoden zur herstellung immunologischer reagentien positionsspezifisch für phosphorylierungen - Google Patents

Methoden zur herstellung immunologischer reagentien positionsspezifisch für phosphorylierungen

Info

Publication number
DE60027542D1
DE60027542D1 DE60027542T DE60027542T DE60027542D1 DE 60027542 D1 DE60027542 D1 DE 60027542D1 DE 60027542 T DE60027542 T DE 60027542T DE 60027542 T DE60027542 T DE 60027542T DE 60027542 D1 DE60027542 D1 DE 60027542D1
Authority
DE
Germany
Prior art keywords
mimetic
linkage
polypeptide
produce
specific
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60027542T
Other languages
English (en)
Other versions
DE60027542T2 (de
Inventor
W Anderson
Ettore Appella
Kazuyasu Sakaguchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
US Department of Health and Human Services
Brookhaven Science Associates LLC
Original Assignee
US Department of Health and Human Services
Brookhaven Science Associates LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by US Department of Health and Human Services, Brookhaven Science Associates LLC filed Critical US Department of Health and Human Services
Application granted granted Critical
Publication of DE60027542D1 publication Critical patent/DE60027542D1/de
Publication of DE60027542T2 publication Critical patent/DE60027542T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
DE60027542T 1999-01-25 2000-01-25 Methoden zur herstellung immunologischer reagentien positionsspezifisch für phosphorylierungen Expired - Lifetime DE60027542T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US236415 1999-01-25
US09/236,415 US6309863B1 (en) 1999-01-25 1999-01-25 Methods for generating phosphorylation site-specific immunological reagents
PCT/US2000/001796 WO2000043422A1 (en) 1999-01-25 2000-01-25 Methods for generating phosphorylation site-specific immunological reagents

Publications (2)

Publication Number Publication Date
DE60027542D1 true DE60027542D1 (de) 2006-06-01
DE60027542T2 DE60027542T2 (de) 2007-05-03

Family

ID=22889404

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60027542T Expired - Lifetime DE60027542T2 (de) 1999-01-25 2000-01-25 Methoden zur herstellung immunologischer reagentien positionsspezifisch für phosphorylierungen

Country Status (16)

Country Link
US (1) US6309863B1 (de)
EP (1) EP1147137B9 (de)
JP (1) JP3891542B2 (de)
AT (1) ATE324382T1 (de)
AU (1) AU767969B2 (de)
BR (1) BR0008977A (de)
CA (1) CA2360511C (de)
DE (1) DE60027542T2 (de)
HU (1) HUP0105309A3 (de)
IL (2) IL144471A0 (de)
MX (1) MXPA01007323A (de)
NO (1) NO20013636L (de)
NZ (1) NZ512868A (de)
UA (1) UA73109C2 (de)
WO (1) WO2000043422A1 (de)
ZA (1) ZA200105520B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030162230A1 (en) 2000-09-27 2003-08-28 Reagan Kevin J. Method for quantifying phosphokinase activity on proteins
WO2003057238A1 (en) * 2001-12-28 2003-07-17 Oregon Health & Science University Agents that recognize src when phosphorylated at serine 17
US7452676B2 (en) * 2003-01-16 2008-11-18 Uti Limited Partnership Monoclonal antibodies to RNA binding protein GW182
EP1972639A3 (de) * 2007-03-07 2008-12-03 Cell Signaling Technology, Inc. Reagenzien zur Erkennung von Proteinphosphorylierung in Karzinom-Signalwegen
CA2719247C (en) * 2008-03-25 2017-03-21 The Regents Of The University Of Michigan Ikki inhibitor therapies and screening methods, and related ikki diagnostics
US8445706B2 (en) * 2008-09-05 2013-05-21 Board Of Trustees Of Northern Illinois University Unnatural amino acids capable of covalently modifying protein phosphatases and their use as general and specific inhibitors and probes
EP2576614A4 (de) * 2010-05-24 2013-11-13 Phosimmune Inc Klasse-i-mhc-phosphopeptide für krebs-immuntherapie und -diagnose
US10245255B2 (en) 2011-02-14 2019-04-02 The Regents Of The University Of Michigan Compositions and methods for the treatment of obesity and related disorders
EP2854842A4 (de) 2012-05-25 2016-11-02 Agenus Inc Identifizierung von mhc-klasse-i-phosphopeptidantigenen von brustkrebs mittels shla-technologie und komplementärer anreicherungsstrategien
EP3718556A3 (de) 2012-08-31 2020-12-30 University Of Virginia Patent Foundation Zielpeptide für immuntherapie und diagnostik
EP2892544A4 (de) 2012-09-05 2016-11-02 Univ Virginia Patent Found Target-peptide für therapie und diagnostik von kolorektalkarzinomen
WO2014179734A1 (en) 2013-05-02 2014-11-06 The Regents Of The University Of Michigan Deuterated amlexanox
US10214536B2 (en) 2016-01-29 2019-02-26 The Regents Of The University Of Michigan Amlexanox analogs
CN106046047B (zh) * 2016-05-26 2018-10-02 清华大学 制备磷酸化丝氨酸膦酸模拟物的方法
US20230212271A1 (en) * 2021-09-27 2023-07-06 Abbratech Inc. Compositions and methods for linear and conformational site-specific antibodies and methods of making the same

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4543439A (en) * 1982-12-13 1985-09-24 Massachusetts Institute Of Technology Production and use of monoclonal antibodies to phosphotyrosine-containing proteins
DE4009848A1 (de) * 1990-03-27 1991-10-02 Boehringer Mannheim Gmbh Verfahren zum nachweis von phosphoryliertes tyrosin enthaltenden proteinen
CA2117913C (en) * 1992-04-10 2006-05-09 Richard J. Epstein Activation-state-specific phosphoprotein immunodetection
WO1994018324A2 (en) * 1993-02-12 1994-08-18 The Salk Institute For Biological Studies Phospho-specific antibodies against transcription factors, more specifically against a creb derived peptide
US6495356B1 (en) * 1999-11-30 2002-12-17 The Regents Of The University Of California Beryllofluoride analogues of acyl phosphate polypeptides

Also Published As

Publication number Publication date
JP3891542B2 (ja) 2007-03-14
EP1147137A4 (de) 2004-12-29
EP1147137B1 (de) 2006-04-26
WO2000043422A1 (en) 2000-07-27
EP1147137B9 (de) 2006-11-02
IL144471A0 (en) 2002-05-23
BR0008977A (pt) 2002-02-13
CA2360511A1 (en) 2000-07-27
IL144471A (en) 2006-06-11
MXPA01007323A (es) 2002-06-04
AU767969B2 (en) 2003-11-27
JP2003517451A (ja) 2003-05-27
UA73109C2 (en) 2005-06-15
CA2360511C (en) 2012-04-10
DE60027542T2 (de) 2007-05-03
EP1147137A1 (de) 2001-10-24
HUP0105309A2 (hu) 2002-04-29
ZA200105520B (en) 2002-01-17
ATE324382T1 (de) 2006-05-15
NZ512868A (en) 2003-11-28
NO20013636D0 (no) 2001-07-24
US6309863B1 (en) 2001-10-30
HUP0105309A3 (en) 2004-09-28
NO20013636L (no) 2001-09-19
AU3582800A (en) 2000-08-07

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