DE3886140T2 - Device and method for diluting and mixing liquid samples. - Google Patents

Device and method for diluting and mixing liquid samples.

Info

Publication number
DE3886140T2
DE3886140T2 DE3886140T DE3886140T DE3886140T2 DE 3886140 T2 DE3886140 T2 DE 3886140T2 DE 3886140 T DE3886140 T DE 3886140T DE 3886140 T DE3886140 T DE 3886140T DE 3886140 T2 DE3886140 T2 DE 3886140T2
Authority
DE
Germany
Prior art keywords
diluting
liquid samples
mixing liquid
samples
mixing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE3886140T
Other languages
German (de)
Other versions
DE3886140D1 (en
Inventor
Ian Gibbons
Robert S Hillman
Channing R Robertson
Michael M Gorin
Michael E Cobb
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics Corp
Original Assignee
Biotrack Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/090,026 external-priority patent/US4868129A/en
Priority claimed from US07/117,791 external-priority patent/US5077017A/en
Application filed by Biotrack Inc filed Critical Biotrack Inc
Publication of DE3886140D1 publication Critical patent/DE3886140D1/en
Application granted granted Critical
Publication of DE3886140T2 publication Critical patent/DE3886140T2/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/38—Diluting, dispersing or mixing samples
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/45—Magnetic mixers; Mixers with magnetically driven stirrers
    • B01F33/452—Magnetic mixers; Mixers with magnetically driven stirrers using independent floating stirring elements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/80—Forming a predetermined ratio of the substances to be mixed
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/02—Food
    • G01N33/04—Dairy products
DE3886140T 1987-08-27 1988-08-26 Device and method for diluting and mixing liquid samples. Expired - Fee Related DE3886140T2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/090,026 US4868129A (en) 1987-08-27 1987-08-27 Apparatus and method for dilution and mixing of liquid samples
US07/117,791 US5077017A (en) 1987-11-05 1987-11-05 Integrated serial dilution and mixing cartridge

Publications (2)

Publication Number Publication Date
DE3886140D1 DE3886140D1 (en) 1994-01-20
DE3886140T2 true DE3886140T2 (en) 1994-05-19

Family

ID=26781444

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3886140T Expired - Fee Related DE3886140T2 (en) 1987-08-27 1988-08-26 Device and method for diluting and mixing liquid samples.

Country Status (6)

Country Link
EP (1) EP0305210B1 (en)
JP (1) JPH0756492B2 (en)
AU (1) AU615208B2 (en)
CA (1) CA1333850C (en)
DE (1) DE3886140T2 (en)
ES (1) ES2049254T3 (en)

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US5104813A (en) * 1989-04-13 1992-04-14 Biotrack, Inc. Dilution and mixing cartridge
US5225163A (en) * 1989-08-18 1993-07-06 Angenics, Inc. Reaction apparatus employing gravitational flow
WO1991002589A1 (en) * 1989-08-18 1991-03-07 Cambridge Bioscience Corporation Reaction apparatus and method employing gravitational flow
US5230866A (en) * 1991-03-01 1993-07-27 Biotrack, Inc. Capillary stop-flow junction having improved stability against accidental fluid flow
EP0501796A3 (en) * 1991-03-01 1993-10-06 Biotrack, Inc. Capillary stop-flow junction having improved stability against accidental fluid flow
EP1577010A3 (en) * 1995-12-05 2005-11-16 Tecan Trading AG Microsystem platform and its use
ATE291225T1 (en) * 1995-12-05 2005-04-15 Gamera Bioscience Corp DEVICE AND METHOD FOR MOVING FLUID USING CENTRIFUGAL ACCELERATION IN AUTOMATIC LABORATORY TREATMENT
US6709869B2 (en) 1995-12-18 2004-03-23 Tecan Trading Ag Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system
US6143248A (en) * 1996-08-12 2000-11-07 Gamera Bioscience Corp. Capillary microvalve
WO1998028623A1 (en) 1996-12-20 1998-07-02 Gamera Bioscience Corporation An affinity binding-based system for detecting particulates in a fluid
US6632399B1 (en) 1998-05-22 2003-10-14 Tecan Trading Ag Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system for performing biological fluid assays
US6063589A (en) 1997-05-23 2000-05-16 Gamera Bioscience Corporation Devices and methods for using centripetal acceleration to drive fluid movement on a microfluidics system
WO1999009394A1 (en) 1997-08-15 1999-02-25 Alexion Pharmaceuticals, Inc. Apparatus for performing assays at reaction sites
SE9803734D0 (en) * 1998-10-30 1998-10-30 Amersham Pharm Biotech Ab Liquid handling system
US6193471B1 (en) * 1999-06-30 2001-02-27 Perseptive Biosystems, Inc. Pneumatic control of formation and transport of small volume liquid samples
AU1763401A (en) * 1999-11-15 2001-05-30 I-Stat Corporation Apparatus and method for assaying coagulation in fluid samples
DE10057895B4 (en) * 2000-11-22 2009-06-18 peS Gesellschaft für medizinische Diagnosesysteme mbH Apparatus and method for sample preparation of liquid samples
US7429354B2 (en) 2001-03-19 2008-09-30 Gyros Patent Ab Structural units that define fluidic functions
US6919058B2 (en) 2001-08-28 2005-07-19 Gyros Ab Retaining microfluidic microcavity and other microfluidic structures
EP1483052B1 (en) 2001-08-28 2010-12-22 Gyros Patent Ab Retaining microfluidic microcavity and other microfluidic structures
WO2003072254A1 (en) * 2002-02-22 2003-09-04 Nanostream, Inc. Ratiometric dilution devices and methods
JP4210783B2 (en) 2002-09-26 2009-01-21 アークレイ株式会社 Analysis tool
DE102004022423A1 (en) * 2004-05-06 2005-12-15 Siemens Ag microfluidic
JP2007003414A (en) * 2005-06-24 2007-01-11 Arkray Inc Cartridge for analyzer
JP4660662B2 (en) * 2005-09-06 2011-03-30 アークレイ株式会社 cartridge
JP4797619B2 (en) * 2005-12-22 2011-10-19 東レ株式会社 Analysis chip and analysis method of test substance
JP5241209B2 (en) * 2007-11-26 2013-07-17 株式会社日立ハイテクノロジーズ Sample pretreatment device and sample analysis method
US9040285B2 (en) 2008-12-18 2015-05-26 Koninklijkle Philips N.V. Sensing device for sensing a fluid
JP5888885B2 (en) * 2010-06-23 2016-03-22 アークレイ株式会社 Measuring apparatus, measuring method, measuring program, and measuring system
CN104813170B (en) * 2012-11-15 2017-11-24 安捷伦科技有限公司 Sample to assignable dilution rate dilutes
JP5833716B1 (en) * 2014-07-24 2015-12-16 日本電信電話株式会社 Blood coagulation test method and flow channel chip for blood coagulation test
CN109415722A (en) 2016-01-29 2019-03-01 普瑞珍生物系统公司 Isotachophoresis for nucleic acid purification
AU2018312570B2 (en) 2017-08-02 2024-01-11 Purigen Biosystems, Inc. Systems, devices, and methods for isotachophoresis
WO2019168835A1 (en) * 2018-02-27 2019-09-06 CytoChip, Inc. Devices and methods for sample analysis with serial dilution
CN108393105B (en) * 2018-04-20 2023-08-25 华南师范大学 Microfluidic chip, control system and control method thereof
WO2020149067A1 (en) * 2019-01-17 2020-07-23 日本分光株式会社 Static mixer

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE330624B (en) * 1965-09-02 1970-11-23 Medicinskkemiska Lab Calab Ab
US3799742A (en) * 1971-12-20 1974-03-26 C Coleman Miniaturized integrated analytical test container
US3869068A (en) * 1974-06-06 1975-03-04 Hyperion Inc Diluter probe assembly
US4426451A (en) * 1981-01-28 1984-01-17 Eastman Kodak Company Multi-zoned reaction vessel having pressure-actuatable control means between zones
US4503012A (en) * 1983-04-19 1985-03-05 American Monitor Corporation Reagent dispensing system
FI834387A0 (en) * 1983-11-30 1983-11-30 Labsystems Oy FOERFARANDE FOER UTSPAEDNING AV VAETSKEPROV

Also Published As

Publication number Publication date
CA1333850C (en) 1995-01-10
AU615208B2 (en) 1991-09-26
EP0305210A3 (en) 1989-10-11
JPH01257268A (en) 1989-10-13
ES2049254T3 (en) 1994-04-16
EP0305210B1 (en) 1993-12-08
DE3886140D1 (en) 1994-01-20
JPH0756492B2 (en) 1995-06-14
AU2163988A (en) 1989-03-02
EP0305210A2 (en) 1989-03-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: ROCHE DIAGNOSTICS CORP., INDIANAPOLIS, IND., US

8339 Ceased/non-payment of the annual fee