DE3852140D1 - Produktion von Proteinen in aktiven Formen. - Google Patents
Produktion von Proteinen in aktiven Formen.Info
- Publication number
- DE3852140D1 DE3852140D1 DE3852140T DE3852140T DE3852140D1 DE 3852140 D1 DE3852140 D1 DE 3852140D1 DE 3852140 T DE3852140 T DE 3852140T DE 3852140 T DE3852140 T DE 3852140T DE 3852140 D1 DE3852140 D1 DE 3852140D1
- Authority
- DE
- Germany
- Prior art keywords
- protein
- proteins
- production
- rupturing
- active forms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormones [GH] (Somatotropin)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
- C07K1/1136—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by reversible modification of the secondary, tertiary or quarternary structure, e.g. using denaturating or stabilising agents
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AUPI046287 | 1987-02-20 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE3852140D1 true DE3852140D1 (de) | 1995-01-05 |
DE3852140T2 DE3852140T2 (de) | 1995-04-06 |
Family
ID=3772028
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE3852140T Expired - Fee Related DE3852140T2 (de) | 1987-02-20 | 1988-02-16 | Produktion von Proteinen in aktiven Formen. |
Country Status (10)
Country | Link |
---|---|
US (1) | US4966963A (de) |
EP (1) | EP0279619B1 (de) |
JP (1) | JPS63264598A (de) |
AT (1) | ATE114319T1 (de) |
AU (1) | AU612133B2 (de) |
CA (1) | CA1326106C (de) |
DE (1) | DE3852140T2 (de) |
ES (1) | ES2065906T3 (de) |
NZ (1) | NZ223559A (de) |
ZA (1) | ZA881067B (de) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU612133B2 (en) * | 1987-02-20 | 1991-07-04 | Natinco Nv | Production of proteins in active forms |
AU609824B2 (en) * | 1987-06-15 | 1991-05-09 | Southern Cross Biotech Pty Ltd. | Production of proteins in active forms |
JPH03500601A (ja) * | 1987-06-26 | 1991-02-14 | コモンウェルス サイエンティフィック アンド インダストリアル リサーチ オーガナイゼイション | ウィルス中和及び保護モノクローナル抗体により認識されるibdv vp2エピトープ |
US5136027A (en) * | 1989-05-02 | 1992-08-04 | Abbott Laboratories | Method for renaturing proteins in the presence of alkyl sulfate detergents |
US5101018A (en) * | 1989-06-12 | 1992-03-31 | International Minerals & Chemical Corp. | Method for recovering recombinant proteins |
ATE113060T1 (de) * | 1989-12-05 | 1994-11-15 | American Cyanamid Co | Methode zur auflösung und naturation von somatotropin unter verwendung von einer niedrigen harnstoffkonzentration. |
ES2119779T3 (es) * | 1990-09-05 | 1998-10-16 | Southern Cross Biotech Pty Ltd | Solubilizacion de proteinas en formas activas. |
US6566098B1 (en) * | 1990-09-14 | 2003-05-20 | The United States Of America As Represented By The Department Of Health And Human Services | DNA encoding truncated hepatocyte growth factor variants |
GB2281558B (en) * | 1993-09-07 | 1997-02-19 | Joseph Matthew Gaugas | Supplying sulphur to plants |
US5861372A (en) * | 1996-02-22 | 1999-01-19 | The Children's Medical Center Corporation | Aggregate angiostatin and method of use |
US6346510B1 (en) | 1995-10-23 | 2002-02-12 | The Children's Medical Center Corporation | Therapeutic antiangiogenic endostatin compositions |
US5840838A (en) * | 1996-02-29 | 1998-11-24 | University Of Kentucky Research Foundation | Process for enhancing the activity of amyloid β peptides |
US20030190307A1 (en) * | 1996-12-24 | 2003-10-09 | Biogen, Inc. | Stable liquid interferon formulations |
US6566583B1 (en) | 1997-06-04 | 2003-05-20 | Daniel Facciotti | Schizochytrium PKS genes |
DK2316475T3 (da) | 1998-08-06 | 2017-11-20 | Mountain View Pharmaceuticals Inc | Isoleret tetramer urikase |
US8148123B2 (en) | 2005-04-11 | 2012-04-03 | Savient Pharmaceuticals, Inc. | Methods for lowering elevated uric acid levels using intravenous injections of PEG-uricase |
LT3321359T (lt) | 2005-04-11 | 2021-05-10 | Horizon Pharma Rheumatology Llc | Urato oksidazės variantinės formos ir jų panaudojimas |
CN101194016B (zh) * | 2005-04-11 | 2012-09-05 | 萨文特医药公司 | 尿酸氧化酶的变体形式及其用途 |
US20080159976A1 (en) * | 2005-04-11 | 2008-07-03 | Jacob Hartman | Methods for lowering elevated uric acid levels using intravenous injections of PEG-uricase |
WO2006125452A1 (en) * | 2005-05-23 | 2006-11-30 | Universite De Geneve | Injectable superparamagnetic nanoparticles for treatment by hyperthermia and use for forming an hyperthermic implant |
PL2013225T3 (pl) * | 2006-04-12 | 2015-06-30 | Crealta Pharmaceuticals Llc | Oczyszczanie białek z zastosowaniem kationowego środka powierzchniowo czynnego |
EP2358909B1 (de) | 2008-11-17 | 2015-09-02 | Cornell University | System zur protokollierung von wechselwirkungen zwischen proteinen im bakteriellen periplasma |
WO2010151823A1 (en) | 2009-06-25 | 2010-12-29 | Savient Pharmaceuticals Inc. | Methods and kits for predicting infusion reaction risk and antibody-mediated loss of response by monitoring serum uric acid during pegylated uricase therapy |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2829089A1 (de) * | 1977-07-13 | 1979-02-01 | Sandoz Ag | Subunit-vakzine |
US4462940A (en) * | 1982-09-23 | 1984-07-31 | Cetus Corporation | Process for the recovery of human β-interferon-like polypeptides |
GR79124B (de) * | 1982-12-22 | 1984-10-02 | Genentech Inc | |
ES8800957A1 (es) * | 1985-02-22 | 1987-12-01 | Monsanto Co | Un metodo para la solubilizacion y renaturalizacion de proteina somatotropina |
US4731440A (en) * | 1985-02-22 | 1988-03-15 | Monsanto Company | Method of somatotropin solubilization using dimethylsulfone and naturation |
US4766224A (en) * | 1985-08-19 | 1988-08-23 | International Minerals & Chemical Corp. | Purification and activation of proteins from insoluble inclusion bodies |
AU597924B2 (en) * | 1985-12-11 | 1990-06-14 | Natinco Nv | Solubilization of protein aggregates |
AU612133B2 (en) * | 1987-02-20 | 1991-07-04 | Natinco Nv | Production of proteins in active forms |
AU607988B2 (en) * | 1987-04-21 | 1991-03-21 | Southern Cross Biotech Pty Ltd. | Production of proteins in active forms |
AU1763188A (en) * | 1987-06-15 | 1988-12-15 | Bunge (Australia) Pty Ltd | Recovery of proteins in active form |
-
1988
- 1988-02-08 AU AU11412/88A patent/AU612133B2/en not_active Ceased
- 1988-02-11 US US07/154,938 patent/US4966963A/en not_active Expired - Lifetime
- 1988-02-16 AT AT88301257T patent/ATE114319T1/de not_active IP Right Cessation
- 1988-02-16 DE DE3852140T patent/DE3852140T2/de not_active Expired - Fee Related
- 1988-02-16 ZA ZA881067A patent/ZA881067B/xx unknown
- 1988-02-16 ES ES88301257T patent/ES2065906T3/es not_active Expired - Lifetime
- 1988-02-16 EP EP88301257A patent/EP0279619B1/de not_active Expired - Lifetime
- 1988-02-16 CA CA000558944A patent/CA1326106C/en not_active Expired - Fee Related
- 1988-02-18 NZ NZ223559A patent/NZ223559A/xx unknown
- 1988-02-19 JP JP63037341A patent/JPS63264598A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
DE3852140T2 (de) | 1995-04-06 |
ATE114319T1 (de) | 1994-12-15 |
ZA881067B (en) | 1988-08-11 |
EP0279619B1 (de) | 1994-11-23 |
ES2065906T3 (es) | 1995-03-01 |
NZ223559A (en) | 1989-09-27 |
EP0279619A2 (de) | 1988-08-24 |
CA1326106C (en) | 1994-01-11 |
JPS63264598A (ja) | 1988-11-01 |
US4966963A (en) | 1990-10-30 |
AU612133B2 (en) | 1991-07-04 |
AU1141288A (en) | 1988-08-25 |
EP0279619A3 (en) | 1990-04-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: NANTINCO, NV, WILLENSTED, CURACAO, AN |
|
8339 | Ceased/non-payment of the annual fee |