DE3852116T2 - Herstellung von Proteinen in aktiver Form. - Google Patents

Herstellung von Proteinen in aktiver Form.

Info

Publication number
DE3852116T2
DE3852116T2 DE3852116T DE3852116T DE3852116T2 DE 3852116 T2 DE3852116 T2 DE 3852116T2 DE 3852116 T DE3852116 T DE 3852116T DE 3852116 T DE3852116 T DE 3852116T DE 3852116 T2 DE3852116 T2 DE 3852116T2
Authority
DE
Germany
Prior art keywords
proteins
production
host cells
active form
source
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE3852116T
Other languages
English (en)
Other versions
DE3852116D1 (de
Inventor
Joseph John Patroni Jo Patroni
Malcolm Roy Brandon Ma Brandon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Southern Cross Biotech Pty Ltd
Original Assignee
Southern Cross Biotech Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Southern Cross Biotech Pty Ltd filed Critical Southern Cross Biotech Pty Ltd
Publication of DE3852116D1 publication Critical patent/DE3852116D1/de
Application granted granted Critical
Publication of DE3852116T2 publication Critical patent/DE3852116T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/06—Lysis of microorganisms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormones [GH] (Somatotropin)
DE3852116T 1987-06-15 1988-06-14 Herstellung von Proteinen in aktiver Form. Expired - Fee Related DE3852116T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AUPI247287 1987-06-15

Publications (2)

Publication Number Publication Date
DE3852116D1 DE3852116D1 (de) 1994-12-22
DE3852116T2 true DE3852116T2 (de) 1995-03-30

Family

ID=3772234

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3852116T Expired - Fee Related DE3852116T2 (de) 1987-06-15 1988-06-14 Herstellung von Proteinen in aktiver Form.

Country Status (14)

Country Link
US (1) US4992531A (de)
JP (1) JPS6447389A (de)
KR (1) KR0126767B1 (de)
CN (1) CN1032425C (de)
AT (1) ATE114156T1 (de)
AU (1) AU609824B2 (de)
CA (1) CA1305284C (de)
DE (1) DE3852116T2 (de)
DK (1) DK322188A (de)
ES (1) ES2065911T3 (de)
IE (1) IE66334B1 (de)
NO (1) NO882635L (de)
NZ (1) NZ225032A (de)
ZA (1) ZA884212B (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU607988B2 (en) * 1987-04-21 1991-03-21 Southern Cross Biotech Pty Ltd. Production of proteins in active forms
EP0295859B1 (de) * 1987-06-15 1994-11-17 Southern Cross Biotech Pty.Ltd. Herstellung von Proteinen in aktiver Form
US5102989A (en) * 1991-03-15 1992-04-07 Merck & Co., Inc. Method of stabilizing recombinant hepatitis B virus surface proteins from recombinant host cells
US5252216A (en) * 1992-03-24 1993-10-12 Smithkline Beecham Corporation Protein purification
JPH0774232B2 (ja) * 1992-08-31 1995-08-09 農林水産省食品総合研究所長 界面活性剤を用いたタンパク質の新規な精製法
JP3279362B2 (ja) * 1992-10-05 2002-04-30 井上 聰一 糖尿病判定方法及び糖尿病判定装置
JP3319812B2 (ja) * 1993-04-05 2002-09-03 井上 聰一 リウマチ判定方法及びリウマチ判定装置
US20030190307A1 (en) * 1996-12-24 2003-10-09 Biogen, Inc. Stable liquid interferon formulations
US7153943B2 (en) * 1997-07-14 2006-12-26 Bolder Biotechnology, Inc. Derivatives of growth hormone and related proteins, and methods of use thereof
DK2158923T3 (da) 1998-08-06 2013-03-25 Mountain View Pharmaceuticals Peg-uratoxidase-konjugater og anvendelse deraf
ES2290142T3 (es) * 2000-05-16 2008-02-16 Bolder Biotechnology, Inc. Metodos para replegamiento de proteinas que contiene residuos de cisteina libre.
ATE513838T1 (de) 2002-09-20 2011-07-15 Promega Corp Auf lumineszenz basierende verfahren und sonden zur messung der cytochrom-p450-aktivität
WO2004042003A2 (en) * 2002-11-01 2004-05-21 Promega Corporation Cell lysis compositions, methods of use, apparatus, and kit
DE10309691B4 (de) 2003-02-28 2018-10-04 Hans-Knöll-Institut für Naturstoff-Forschung e.V. Gewinnung von löslichen Proteinen aus der Biomasse rekombinanter Mikroorganismen
US20040180445A1 (en) * 2003-03-12 2004-09-16 Domanico Michael J. Methods and compositions for purification of nucleic acid from a host cell
US8188224B2 (en) 2005-04-11 2012-05-29 Savient Pharmaceuticals, Inc. Variant forms of urate oxidase and use thereof
CZ2007700A3 (cs) 2005-04-11 2008-02-27 Savient Pharmaceuticals, Inc. Variantní forma urátoxidázy a její použití
US20080159976A1 (en) * 2005-04-11 2008-07-03 Jacob Hartman Methods for lowering elevated uric acid levels using intravenous injections of PEG-uricase
US8148123B2 (en) 2005-04-11 2012-04-03 Savient Pharmaceuticals, Inc. Methods for lowering elevated uric acid levels using intravenous injections of PEG-uricase
JP2008545665A (ja) * 2005-05-23 2008-12-18 ユニベルシテ ドゥ ジュネーブ 高体温による処置のための注入可能な超常磁性ナノ粒子および高体温インプラントを形成するための使用
WO2006130551A2 (en) * 2005-05-31 2006-12-07 Promega Corporation Luminogenic and fluorogenic compounds and methods to detect molecules or conditions
KR101288027B1 (ko) 2006-04-12 2013-07-22 새비언트 파마수티컬즈 인크. 양이온 계면활성제를 이용한 단백질 정제 방법
EP2102355B1 (de) 2006-12-14 2016-03-02 Bolder Biotechnology, Inc. Proteine und peptide mit langer wirkung sowie verfahren zu ihrer herstellung und verwendung
WO2010021686A1 (en) * 2008-08-18 2010-02-25 Promega Corporation Luminogenic compounds and methods to detect cytochrome p450 3a enzymes
GB0901434D0 (en) * 2009-01-29 2009-03-11 Univ Strathclyde Ballast water treatment system
CN102803954A (zh) 2009-06-25 2012-11-28 萨文特制药公司 通过监测peg化尿酸酶治疗期间的血清尿酸预测输液反应风险和抗体介导的响应丧失的方法和试剂盒
CN102905690B (zh) * 2010-05-21 2016-03-30 西门子医疗保健诊断公司 两性离子试剂
CN102965317A (zh) * 2012-11-27 2013-03-13 江南大学 一种产牛磺酸菌株的筛选方法及用该菌株发酵法生产牛磺酸
EP3099683B1 (de) 2014-01-29 2020-08-05 Promega Corporation Chinonmaskierte sonden als markierungsreagenzien für zellaufnahmemessungen
US10131898B2 (en) * 2014-07-22 2018-11-20 Bio-Rad Laboratories, Inc. Buffers for use with polymerases

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4476049A (en) * 1983-09-20 1984-10-09 Hoffmann-La Roche Inc. Method for the extraction of immune interferon
US4677196A (en) * 1985-09-06 1987-06-30 International Minerals & Chemical Corp. Purification and activation of proteins from insoluble inclusion bodies
US4681761A (en) * 1985-10-24 1987-07-21 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University Major iron-regulated protein of Neisseria gonorrhoeae and its use as vaccine
AU597924B2 (en) * 1985-12-11 1990-06-14 Natinco Nv Solubilization of protein aggregates
AU612133B2 (en) * 1987-02-20 1991-07-04 Natinco Nv Production of proteins in active forms
AU607988B2 (en) * 1987-04-21 1991-03-21 Southern Cross Biotech Pty Ltd. Production of proteins in active forms

Also Published As

Publication number Publication date
KR0126767B1 (ko) 1997-12-29
NO882635D0 (no) 1988-06-15
ES2065911T3 (es) 1995-03-01
JPS6447389A (en) 1989-02-21
DE3852116D1 (de) 1994-12-22
KR900000380A (ko) 1990-01-30
CN88103725A (zh) 1988-12-28
IE881815L (en) 1988-12-15
IE66334B1 (en) 1995-12-27
AU1763288A (en) 1988-12-15
US4992531A (en) 1991-02-12
ZA884212B (en) 1989-03-29
CN1032425C (zh) 1996-07-31
AU609824B2 (en) 1991-05-09
CA1305284C (en) 1992-07-14
NZ225032A (en) 1991-02-26
DK322188D0 (da) 1988-06-14
NO882635L (no) 1988-12-19
DK322188A (da) 1988-12-17
ATE114156T1 (de) 1994-12-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee