DE3680379D1 - Streulicht/fluoreszenzlicht trennender buendelteiler in einem durchflusszytometer. - Google Patents

Streulicht/fluoreszenzlicht trennender buendelteiler in einem durchflusszytometer.

Info

Publication number
DE3680379D1
DE3680379D1 DE8686101016T DE3680379T DE3680379D1 DE 3680379 D1 DE3680379 D1 DE 3680379D1 DE 8686101016 T DE8686101016 T DE 8686101016T DE 3680379 T DE3680379 T DE 3680379T DE 3680379 D1 DE3680379 D1 DE 3680379D1
Authority
DE
Germany
Prior art keywords
light
bunch
divider
disconnecting
flow cytometer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8686101016T
Other languages
English (en)
Inventor
Vernon Chupp
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Becton Dickinson and Co
Original Assignee
Becton Dickinson and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson and Co filed Critical Becton Dickinson and Co
Application granted granted Critical
Publication of DE3680379D1 publication Critical patent/DE3680379D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Electro-optical investigation, e.g. flow cytometers
    • G01N15/1434—Electro-optical investigation, e.g. flow cytometers using an analyser being characterised by its optical arrangement
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B27/00—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
    • G02B27/10—Beam splitting or combining systems
    • G02B27/14—Beam splitting or combining systems operating by reflection only
    • G02B27/144—Beam splitting or combining systems operating by reflection only using partially transparent surfaces without spectral selectivity
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B27/00—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
    • G02B27/10—Beam splitting or combining systems
    • G02B27/14—Beam splitting or combining systems operating by reflection only
    • G02B27/145—Beam splitting or combining systems operating by reflection only having sequential partially reflecting surfaces
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Electro-optical investigation, e.g. flow cytometers
    • G01N15/1456—Electro-optical investigation, e.g. flow cytometers without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459—Electro-optical investigation, e.g. flow cytometers without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
DE8686101016T 1985-05-10 1986-01-25 Streulicht/fluoreszenzlicht trennender buendelteiler in einem durchflusszytometer. Expired - Lifetime DE3680379D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/732,765 US4662742A (en) 1985-05-10 1985-05-10 Scatter/fluorescene beam splitter in a flow cytometry apparatus

Publications (1)

Publication Number Publication Date
DE3680379D1 true DE3680379D1 (de) 1991-08-29

Family

ID=24944863

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686101016T Expired - Lifetime DE3680379D1 (de) 1985-05-10 1986-01-25 Streulicht/fluoreszenzlicht trennender buendelteiler in einem durchflusszytometer.

Country Status (5)

Country Link
US (1) US4662742A (de)
EP (1) EP0200851B1 (de)
JP (1) JPS61260144A (de)
DE (1) DE3680379D1 (de)
MY (1) MY102062A (de)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8601000A (nl) * 1986-04-21 1987-11-16 Jan Greve T H Twente Afdeling Het gebruik van gepolariseerd licht in stromingscytometrie.
JPH06100596B2 (ja) * 1986-09-10 1994-12-12 東亜医用電子株式会社 フロ−サイトメトリ−による白血球の分類方法
JPS63196854A (ja) * 1987-02-10 1988-08-15 Toa Medical Electronics Co Ltd リンパ球亜群の測定方法およびその装置
JPS63246641A (ja) * 1987-04-01 1988-10-13 Ajinomoto Co Inc 蛍光分析計
US4983038A (en) * 1987-04-08 1991-01-08 Hitachi, Ltd. Sheath flow type flow-cell device
US5408307A (en) * 1988-07-11 1995-04-18 Omron Tateisi Electronics Co. Cell analyzer
US5275787A (en) * 1989-10-04 1994-01-04 Canon Kabushiki Kaisha Apparatus for separating or measuring particles to be examined in a sample fluid
US5224058A (en) * 1990-05-01 1993-06-29 Becton, Dickinson And Company Method for data transformation
EP0574508B1 (de) * 1991-02-22 1997-11-12 Coulter Corporation Verfahren und vorrichtung zum reihensichten mikroskopischer zellen unter verwendung von techniken zur streuung polarisierten lichts
JP3213334B2 (ja) * 1991-05-14 2001-10-02 シスメックス株式会社 尿中の細胞分析装置
JPH0589028U (ja) * 1992-05-08 1993-12-03 株式会社ゼクセル 内外気切換ドアの駆動力伝達機構
NO932088L (no) * 1993-06-08 1995-01-05 Oddbjoern Gjelsnes Anordning for anvendelse ved væskeströmscytometri
US5489977A (en) * 1993-08-11 1996-02-06 Texaco Inc. Photomeric means for monitoring solids and fluorescent material in waste water using a falling stream water sampler
US5671046A (en) * 1996-07-01 1997-09-23 Particle Measuring Systems, Inc. Device and method for optically detecting particles in a free liquid stream
US6819411B1 (en) 1997-01-31 2004-11-16 Xy, Inc. Optical apparatus
US6710871B1 (en) 1997-06-09 2004-03-23 Guava Technologies, Inc. Method and apparatus for detecting microparticles in fluid samples
US6149867A (en) 1997-12-31 2000-11-21 Xy, Inc. Sheath fluids and collection systems for sex-specific cytometer sorting of sperm
US6067157A (en) * 1998-10-09 2000-05-23 University Of Washington Dual large angle light scattering detection
US6473171B1 (en) 1999-01-15 2002-10-29 Coors Brewing Company Biocompatible apparatus for ultrasensitive and rapid detection of contaminants in liquids
US6249341B1 (en) * 1999-01-25 2001-06-19 Amnis Corporation Imaging and analyzing parameters of small moving objects such as cells
US20060257884A1 (en) * 2004-05-20 2006-11-16 Amnis Corporation Methods for preparing and analyzing cells having chromosomal abnormalities
US7450229B2 (en) * 1999-01-25 2008-11-11 Amnis Corporation Methods for analyzing inter-cellular phenomena
US8885913B2 (en) 1999-01-25 2014-11-11 Amnis Corporation Detection of circulating tumor cells using imaging flow cytometry
US8131053B2 (en) * 1999-01-25 2012-03-06 Amnis Corporation Detection of circulating tumor cells using imaging flow cytometry
US8406498B2 (en) 1999-01-25 2013-03-26 Amnis Corporation Blood and cell analysis using an imaging flow cytometer
US7208265B1 (en) 1999-11-24 2007-04-24 Xy, Inc. Method of cryopreserving selected sperm cells
AU2002213157A1 (en) 2000-10-12 2002-04-22 Amnis Corporation System and method for high numeric aperture imaging systems
WO2002043574A2 (en) 2000-11-29 2002-06-06 Xy, Inc. System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations
US7713687B2 (en) * 2000-11-29 2010-05-11 Xy, Inc. System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations
JP4595067B2 (ja) * 2002-08-01 2010-12-08 エックスワイ，エルエルシー 低圧精子細胞分離システム
US8486618B2 (en) 2002-08-01 2013-07-16 Xy, Llc Heterogeneous inseminate system
JP2005535346A (ja) 2002-08-15 2005-11-24 エックスワイ，インコーポレイテッド 高分解能フローサイトメーター
US7169548B2 (en) 2002-09-13 2007-01-30 Xy, Inc. Sperm cell processing and preservation systems
BRPI0408857B1 (pt) 2003-03-28 2018-09-11 Inguran Llc aparelho, métodos e processos para separar partículas e para prover esperma de animal separado por sexo
AU2004242121B2 (en) * 2003-05-15 2010-06-24 Xy, Llc. Efficient haploid cell sorting for flow cytometer systems
US8953866B2 (en) 2004-03-16 2015-02-10 Amnis Corporation Method for imaging and differential analysis of cells
ATE538138T1 (de) 2004-03-16 2012-01-15 Amnis Corp Auf bildlicher darstellung beruhende quantifizierung molekularer translokation
US8103080B2 (en) * 2004-03-16 2012-01-24 Amnis Corporation Method for imaging and differential analysis of cells
BRPI0509485A (pt) 2004-03-29 2007-09-11 Monsanto Technology Llc suspensões de esperma para uso em inseminação
EP2269617B1 (de) 2004-07-22 2016-04-27 Inguran, LLC Spermasuspensionen zur Sortierung in X- oder Y-Chromosomen-tragende angereicherte Populationen
US7612871B2 (en) * 2004-09-01 2009-11-03 Honeywell International Inc Frequency-multiplexed detection of multiple wavelength light for flow cytometry
WO2007067999A2 (en) * 2005-12-09 2007-06-14 Amnis Corporation Extended depth of field imaging for high speed object analysis
WO2007121179A2 (en) * 2006-04-11 2007-10-25 Guava Technologies, Inc. Asymmetric capillary for capillary-flow cytometers
US7847923B2 (en) * 2006-09-29 2010-12-07 Millipore Corporation Differentiation of flow cytometry pulses and applications
EP2232231A4 (de) 2007-12-04 2015-12-02 Particle Measuring Syst Nichtorthogonale partikelnachweissysteme und -verfahren
WO2009088492A1 (en) * 2008-01-04 2009-07-16 The Government Of The United States Of America, As Represented By The Secretary Of The Navy Naval Optical separator and method for separating particles suspended in a fluid
US8928881B2 (en) 2009-01-23 2015-01-06 University Of Washington Cytometer with automatic continuous alignment correction
US8451524B2 (en) * 2009-09-29 2013-05-28 Amnis Corporation Modifying the output of a laser to achieve a flat top in the laser's Gaussian beam intensity profile
GB2474235B (en) * 2009-10-06 2013-09-25 Uh Ventures Ltd A low cost apparatus and method for the detection of a fluid- borne particle
US8589851B2 (en) * 2009-12-15 2013-11-19 Memoir Systems, Inc. Intelligent memory system compiler
US8817115B1 (en) 2010-05-05 2014-08-26 Amnis Corporation Spatial alignment of image data from a multichannel detector using a reference image
EP3589196A4 (de) * 2017-03-01 2020-12-23 University of Maryland, College Park Zellklassifizierung auf der basis der mechanischen signatur des zellkerns
EP4314253A2 (de) 2021-03-25 2024-02-07 Iovance Biotherapeutics, Inc. Verfahren und zusammensetzungen für t-zell-kokulturpotenztests und verwendung mit zelltherapieprodukten

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3603689A (en) * 1969-10-13 1971-09-07 Us Air Force Scanning scattered light photometer
US3704933A (en) * 1971-05-04 1972-12-05 Itek Corp See-through readout of electro-optic medium
JPS5068688A (de) * 1973-10-19 1975-06-09
US3901602A (en) * 1974-05-13 1975-08-26 Us Commerce Light scattering method and apparatus for the chemical characterization of particulate matter
JPS55106340A (en) * 1979-02-09 1980-08-15 Toshiba Corp Grain size measuring device
FR2476839A1 (fr) * 1980-02-25 1981-08-28 Anvar Procede de determination du diametre d'une particule en suspension dans un fluide par utilisation d'un rayonnement electromagnetique coherent
JPS5766342A (en) * 1980-04-28 1982-04-22 Agency Of Ind Science & Technol Optical measuring method for suspension particles in medium
JPS5721042A (en) * 1980-07-15 1982-02-03 Mitsubishi Electric Corp Self-retrieval current limiting device
GB2097144A (en) * 1981-03-23 1982-10-27 Tno New method for identifying algae in water samples and apparatus for use in that method
JPS5979834A (ja) * 1982-10-29 1984-05-09 Japan Spectroscopic Co 微小粒子分離装置
JPS59176649A (ja) * 1983-03-28 1984-10-06 Shimadzu Corp 粒子分析装置

Also Published As

Publication number Publication date
JPS61260144A (ja) 1986-11-18
EP0200851A2 (de) 1986-11-12
EP0200851B1 (de) 1991-07-24
JPH0544621B2 (de) 1993-07-06
US4662742A (en) 1987-05-05
EP0200851A3 (en) 1988-05-04
MY102062A (en) 1992-03-31

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