DE3587603D1 - Aus follikularer eierstockfluessigkeit isoliertes inhibin. - Google Patents

Aus follikularer eierstockfluessigkeit isoliertes inhibin.

Info

Publication number
DE3587603D1
DE3587603D1 DE85902422T DE3587603T DE3587603D1 DE 3587603 D1 DE3587603 D1 DE 3587603D1 DE 85902422 T DE85902422 T DE 85902422T DE 3587603 T DE3587603 T DE 3587603T DE 3587603 D1 DE3587603 D1 DE 3587603D1
Authority
DE
Germany
Prior art keywords
inhibin
protein
purified
isolated
subunits
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE85902422T
Other languages
English (en)
Other versions
DE3587603T2 (de
Inventor
David Milne-Robertson
Kretser David De
Milton Hearn
Henry Burger
John Findlay
Francis Morgan
Robert Forage
Richard Wettenhall
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Monash Medical Centre
St Vincents Institute of Medical Research
Biotech Australia Pty Ltd
Prince Henrys Institute of Medical Research
Original Assignee
Monash Medical Centre
St Vincents Institute of Medical Research
Biotech Australia Pty Ltd
Prince Henrys Institute of Medical Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Monash Medical Centre, St Vincents Institute of Medical Research, Biotech Australia Pty Ltd, Prince Henrys Institute of Medical Research filed Critical Monash Medical Centre
Publication of DE3587603D1 publication Critical patent/DE3587603D1/de
Application granted granted Critical
Publication of DE3587603T2 publication Critical patent/DE3587603T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/689Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/815Test for named compound or class of compounds
    • Y10S436/817Steroids or hormones
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/806Antigenic peptides or proteins
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827Proteins from mammals or birds
    • Y10S530/85Reproductive organs or embryos
DE85902422T 1984-06-08 1985-06-03 Aus follikularer eierstockflüssigkeit isoliertes inhibin. Expired - Lifetime DE3587603T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AUPG542784 1984-06-08
AUPH003185 1985-04-04

Publications (2)

Publication Number Publication Date
DE3587603D1 true DE3587603D1 (de) 1993-11-04
DE3587603T2 DE3587603T2 (de) 1994-02-10

Family

ID=25642809

Family Applications (1)

Application Number Title Priority Date Filing Date
DE85902422T Expired - Lifetime DE3587603T2 (de) 1984-06-08 1985-06-03 Aus follikularer eierstockflüssigkeit isoliertes inhibin.

Country Status (10)

Country Link
US (2) US5102807A (de)
EP (1) EP0185034B1 (de)
JP (2) JP2521707B2 (de)
AT (1) ATE95194T1 (de)
CA (1) CA1341617C (de)
DE (1) DE3587603T2 (de)
DK (1) DK171711B1 (de)
NO (1) NO176570C (de)
NZ (1) NZ212248A (de)
WO (1) WO1986000078A1 (de)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1341617C (en) * 1984-06-08 2011-06-28 Henry George Burger Inhibin isolated from ovarian follicular fluid
DE3650689T2 (de) 1985-04-18 1999-04-08 Biotech Australia Pty Ltd Rekombinantes inhibin
NZ231899A (en) * 1985-10-03 1991-07-26 Genentech Inc Human or porcine inhibin peptide compositions and dna encoding them
US5215893A (en) * 1985-10-03 1993-06-01 Genentech, Inc. Nucleic acid encoding the ba chain prodomains of inhibin and method for synthesizing polypeptides using such nucleic acid
US4798885A (en) * 1986-02-07 1989-01-17 Genentech, Inc. Compositions of hormonally active human and porcine inhibin containing an α chain and 62 chain
US5089396A (en) * 1985-10-03 1992-02-18 Genentech, Inc. Nucleic acid encoding β chain prodomains of inhibin and method for synthesizing polypeptides using such nucleic acid
US4864019A (en) * 1985-11-08 1989-09-05 The Salk Institute For Biological Studies Antibodies to inhibin and conjugates produced therefrom
ZA871844B (en) * 1986-03-13 1988-05-25 Biotechnology Pty Ltd Method of assay of inhibin
US5015729A (en) * 1986-06-24 1991-05-14 The Salk Institute For Biological Studies Ovine inhibin
US6150328A (en) * 1986-07-01 2000-11-21 Genetics Institute, Inc. BMP products
DE3853383T2 (de) * 1987-01-29 1995-07-27 Biotech Australia Pty Ltd Isolierung von einkettigen proteinen mit fsh unter- drückender aktivität aus follikularflüssigkeit.
US5032507A (en) * 1987-11-13 1991-07-16 The Salk Institute For Biological Studies Potentiation of erythropoiesis
EP0368992B1 (de) * 1988-05-31 1995-02-15 Biotechnology Australia Pty. Ltd. Wirkung von hormonen
AU638310B2 (en) * 1990-01-08 1993-06-24 Genentech Inc. Method for increasing fertility in females
DE4042408C2 (de) * 1990-01-08 1995-04-06 Stefan Heiden Verwendung von Inhibin- neutralisierenden Antikörpern
US5942220A (en) * 1990-03-16 1999-08-24 Chiron Corporation Inhibitor of cytokine activity and applications thereof
JP3504263B2 (ja) 1991-11-04 2004-03-08 ジェネティックス・インスチチュート・リミテッド・ライアビリティ・カンパニー 組み換え型骨形態形成蛋白ヘテロダイマー、組成物および使用法
US20080139474A1 (en) * 1991-11-04 2008-06-12 David Israel Recombinant bone morphogenetic protein heterodimers, compositions and methods of use
US5428011A (en) * 1992-06-16 1995-06-27 Procyon Biopharma, Inc. Pharmaceutical preparations for inhibiting tumours associated with prostate adenocarcinoma
DE69433530T2 (de) * 1993-05-12 2005-01-05 Genetics Institute, LLC, Cambridge Bmp-11 zusammensetzungen
US6291206B1 (en) * 1993-09-17 2001-09-18 Genetics Institute, Inc. BMP receptor proteins
ES2255059T3 (es) 1993-12-07 2006-06-16 Genetics Institute, Llc Bmp-12, bmp-13 y composiciones suyas inductoras de tendon.
US5725858A (en) * 1994-02-28 1998-03-10 Agritech Technologies, Ltd. Methods of enhancing production performance of birds comprising administration of heterologous protein comprising avian alpha-subunit inhibin protein
US5786179A (en) * 1994-02-28 1998-07-28 Agritech Technologies Ltd. Heterologous protein comprising avian alpha-subunit inhibin protein and methods of producing same
US20030171283A1 (en) * 1994-02-28 2003-09-11 Satterlee Daniel G. Inhibin compositions and methods of enhancing production performance
AUPO638897A0 (en) * 1997-04-23 1997-05-22 Monash University Modulation of cell growth and methods relating thereto
AU780982B2 (en) * 1997-04-23 2005-04-28 Monash University Inhibin modulation of cell growth
TW586934B (en) * 1997-05-19 2004-05-11 Sumitomo Pharma Immunopotentiating composition
US6727224B1 (en) * 1999-02-01 2004-04-27 Genetics Institute, Llc. Methods and compositions for healing and repair of articular cartilage
EP1223990B1 (de) 1999-10-15 2004-07-28 Genetics Institute, LLC Hyaluronsäure enthaltende zusammensetzungen zur abgabe osteogener proteine
CA2355334A1 (en) * 2000-10-16 2002-04-16 Procyon Biopharma Inc. Pharmaceutical preparations and methods for inhibiting tumors
US20030082233A1 (en) * 2000-12-01 2003-05-01 Lyons Karen M. Method and composition for modulating bone growth
TWI329129B (en) * 2001-02-08 2010-08-21 Wyeth Corp Modified and stabilized gdf propeptides and uses thereof
ATE393573T1 (de) * 2001-06-01 2008-05-15 Wyeth Corp Zusammensetzungen für die systemische verabreichung von sequenzen, die für knochenmorphogenese-proteinen kodieren
TWI267378B (en) * 2001-06-08 2006-12-01 Wyeth Corp Calcium phosphate delivery vehicles for osteoinductive proteins
US20050026833A1 (en) * 2001-11-08 2005-02-03 Rabbani Shafaat Ahmed PSP-94: use for treatment of hypercalcemia and bone metastasis
MXPA04011337A (es) * 2002-05-17 2005-07-01 Wyeth Corp Portadores de acido hialuronico solidos y susceptibles de ser inyectados para la liberacion de proteinas osteogenicas.
AU2003297254A1 (en) * 2002-11-07 2004-06-03 Agritech Technology, Ltd Novel compositions that enhance production performance in avians
CN1878565B (zh) * 2003-09-12 2011-01-12 惠氏公司 用于递送成骨蛋白的注射型磷酸钙固体小棒剂和糊剂
EP3336552A3 (de) 2010-11-29 2018-07-25 Mote Marine Laboratory, Inc. Bestimmung der geschlechtsmerkmale von fischen mittels peptidhormonen
BR102014005376A2 (pt) * 2014-03-07 2016-02-10 Ouro Fino Saúde Animal Ltda antígeno de inibina alfa, gene codificante de inibina alfa, gene codificante de proteína de fusão, processo de obtenção do antígeno de inibina alfa, composição antigênica, uso do antígeno de inibina alfa e uso da composição antigênica

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1007568A (en) * 1973-12-13 1977-03-29 Michael C. Attwell Bovine immunoglobulin isolation process
FR2361912A1 (fr) * 1976-08-19 1978-03-17 Merck & Co Inc Vaccin anti-fecondite a base de membrane pellucide solubilisee
US4409139A (en) * 1981-08-10 1983-10-11 The Salk Institute For Biological Studies Gonadostatin
US4423037A (en) * 1982-05-13 1983-12-27 The General Hospital Corporation Inhibitors of peptide hormone action
CA1341617C (en) * 1984-06-08 2011-06-28 Henry George Burger Inhibin isolated from ovarian follicular fluid
DE3650689T2 (de) * 1985-04-18 1999-04-08 Biotech Australia Pty Ltd Rekombinantes inhibin
US4624944A (en) * 1985-06-14 1986-11-25 The Regents Of The University Of California Human seminal alpha-inhibins
US4740587A (en) * 1985-07-18 1988-04-26 The Salk Institute For Biological Studies Inhibin and method of purifying same
US4798885A (en) * 1986-02-07 1989-01-17 Genentech, Inc. Compositions of hormonally active human and porcine inhibin containing an α chain and 62 chain
US4864019A (en) * 1985-11-08 1989-09-05 The Salk Institute For Biological Studies Antibodies to inhibin and conjugates produced therefrom
US4737578A (en) * 1986-02-10 1988-04-12 The Salk Institute For Biological Studies Human inhibin
EP0368992B1 (de) * 1988-05-31 1995-02-15 Biotechnology Australia Pty. Ltd. Wirkung von hormonen

Also Published As

Publication number Publication date
NO176570C (no) 1995-04-26
NO860427L (no) 1986-02-06
JP2521707B2 (ja) 1996-08-07
JPS61502399A (ja) 1986-10-23
ATE95194T1 (de) 1993-10-15
US5102807A (en) 1992-04-07
DE3587603T2 (de) 1994-02-10
CA1341617C (en) 2011-06-28
NZ212248A (en) 1991-05-28
DK60586A (da) 1986-02-07
US5364837A (en) 1994-11-15
JP2583030B2 (ja) 1997-02-19
DK171711B1 (da) 1997-04-01
DK60586D0 (da) 1986-02-07
EP0185034A4 (de) 1988-01-28
NO176570B (no) 1995-01-16
JPH0848636A (ja) 1996-02-20
EP0185034A1 (de) 1986-06-25
WO1986000078A1 (en) 1986-01-03
EP0185034B1 (de) 1993-09-29

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Legal Events

Date Code Title Description
8380 Miscellaneous part iii

Free format text: DIE PATENTINHABER LAUTEN RICHTIG: MONASH UNIVERSITY, CLAYTON, VICTORIA, AU PRINCE HENRY'S INSTITUTE OF MEDICAL RESEARCH, MELBOURNE, AU

8364 No opposition during term of opposition