EP1113804A2
(de)
*
|
1998-09-17 |
2001-07-11 |
Akesis Pharmaceuticals, Inc. |
Kombinationen des chroms oder des vanadiums mit antidiabetika für glukosemetabolismusstörungen
|
US6376549B1
(en)
*
|
1998-09-17 |
2002-04-23 |
Akesis Pharmaceuticals, Inc. |
Metforimin-containing compositions for the treatment of diabetes
|
DE19940130A1
(de)
*
|
1999-08-24 |
2001-03-01 |
Probiodrug Ges Fuer Arzneim |
Neue Effektoren der Dipeptidyl Peptidase IV zur topischen Anwendung
|
WO2001034594A1
(en)
*
|
1999-11-12 |
2001-05-17 |
Guilford Pharmaceuticals, Inc. |
Dipeptidyl peptidase iv inhibitors and methods of making and using dipeptidyl peptidase iv inhibitors
|
US20040152745A1
(en)
*
|
1999-11-12 |
2004-08-05 |
Guilford Pharmaceuticals, Inc. |
Dipeptidyl peptidase IV inhibitors and methods of making and using dipeptidyl peptidase IV inhibitors
|
GB9928330D0
(en)
*
|
1999-11-30 |
2000-01-26 |
Ferring Bv |
Novel antidiabetic agents
|
SG149676A1
(en)
*
|
1999-12-23 |
2009-02-27 |
Novartis Ag |
Use of hypoglycemic agent for treating impaired glucose metabolism
|
US6380398B2
(en)
|
2000-01-04 |
2002-04-30 |
Novo Nordisk A/S |
Therapeutically active and selective heterocyclic compounds that are inhibitors of the enzyme DPP-IV
|
US20080076811A1
(en)
*
|
2000-01-21 |
2008-03-27 |
Bork Balkan |
Combinations comprising depeptidypeptidase-iv inhibitors and antidiabetic agents
|
ES2436610T3
(es)
*
|
2000-01-21 |
2014-01-03 |
Novartis Ag |
Combinaciones que contienen inhibidores de la dipeptidilpeptidasa-IV y agentes antidiabéticos
|
EP1254113A1
(de)
*
|
2000-01-24 |
2002-11-06 |
Novo Nordisk A/S |
N-substituierte 2-cyanopyrrole und -pyrroline die inhibitoren des enzyms ddp-ivsind
|
US6395767B2
(en)
|
2000-03-10 |
2002-05-28 |
Bristol-Myers Squibb Company |
Cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV and method
|
US6432969B1
(en)
|
2000-06-13 |
2002-08-13 |
Novartis Ag |
N-(substituted glycyl)-2 cyanopyrrolidines, pharmaceutical compositions containing them and their use in inhibiting dipeptidyl peptidase-IV
|
MXPA02012272A
(es)
|
2000-07-04 |
2003-04-25 |
Novo Nordisk As |
Compuestos heterociclicos que son inhibidores de la enzima dipeptidilpeptidasa-iv.
|
AR033390A1
(es)
|
2000-08-22 |
2003-12-17 |
Novartis Ag |
Una composicion farmaceutica que comprende un antagonista del receptor at1 y un potenciador de la secrecion de insulina, el uso de dicha composicion para la fabricacion de un medicamento y un kit de partes
|
US20060089389A1
(en)
|
2000-08-22 |
2006-04-27 |
Malcolm Allison |
Combination
|
US20080249016A1
(en)
*
|
2000-09-18 |
2008-10-09 |
Sanos Bioscience A/S |
Use of GLP-2 in a combination treatment for bone-related disorders
|
DE60134251D1
(de)
|
2000-09-18 |
2008-07-10 |
Sanos Bioscience As |
Verwendung von glp-2-peptiden
|
US7371721B2
(en)
*
|
2000-09-18 |
2008-05-13 |
Sanos Bioscience A/S |
Use of GLP-2 and related compounds for the treatment, prevention, diagnosis, and prognosis of bone-related disorders and calcium homeostasis related syndromes
|
US20070135345A1
(en)
*
|
2000-09-18 |
2007-06-14 |
Henriksen Dennis B |
Use of GLP-2 for the treatment or prevention, of bone-related disorders
|
KR100526091B1
(ko)
|
2000-10-06 |
2005-11-08 |
다나베 세이야꾸 가부시키가이샤 |
지방족 질소 함유 오원환 화합물
|
UA74023C2
(en)
*
|
2000-11-10 |
2005-10-17 |
Taisho Pharmaceutical Co Ltd |
Cyanopyrrolidine derivatives
|
TWI243162B
(en)
*
|
2000-11-10 |
2005-11-11 |
Taisho Pharmaceutical Co Ltd |
Cyanopyrrolidine derivatives
|
JPWO2002051836A1
(ja)
*
|
2000-12-27 |
2004-04-22 |
協和醗酵工業株式会社 |
ジペプチジルペプチダーゼ−iv阻害剤
|
GB0109146D0
(en)
*
|
2001-04-11 |
2001-05-30 |
Ferring Bv |
Treatment of type 2 diabetes
|
US20030060494A1
(en)
*
|
2001-05-18 |
2003-03-27 |
Nobuyuki Yasuda |
Pharmaceutical use of N-carbamoylazole derivatives
|
CA2450579A1
(en)
|
2001-06-20 |
2003-01-03 |
Merck & Co., Inc. |
Dipeptidyl peptidase inhibitors for the treatment of diabetes
|
JP2005500308A
(ja)
|
2001-06-20 |
2005-01-06 |
メルク エンド カムパニー インコーポレーテッド |
糖尿病を治療するためのジペプチジルペプチダーゼ阻害剤
|
ATE370943T1
(de)
|
2001-06-27 |
2007-09-15 |
Smithkline Beecham Corp |
Fluoropyrrolidine als dipeptidyl-peptidase inhibitoren
|
JP4300108B2
(ja)
*
|
2001-06-27 |
2009-07-22 |
スミスクライン ビーチャム コーポレーション |
ジペプチジルペプチダーゼ阻害剤としてのピロリジン類
|
IL158923A0
(en)
|
2001-06-27 |
2004-05-12 |
Smithkline Beecham Corp |
Fluoropyrrolidines as dipeptidyl peptidase inhibitors
|
US6709651B2
(en)
*
|
2001-07-03 |
2004-03-23 |
B.M.R.A. Corporation B.V. |
Treatment of substance P-related disorders
|
UA74912C2
(en)
|
2001-07-06 |
2006-02-15 |
Merck & Co Inc |
Beta-aminotetrahydroimidazo-(1,2-a)-pyrazines and tetratriazolo-(4,3-a)-pyrazines as inhibitors of dipeptylpeptidase for the treatment or prevention of diabetes
|
US6861440B2
(en)
|
2001-10-26 |
2005-03-01 |
Hoffmann-La Roche Inc. |
DPP IV inhibitors
|
CA2464995A1
(en)
*
|
2001-10-31 |
2003-05-08 |
Novartis Ag |
Methods to treat diabetes and related conditions based on polymorphisms in the tcf1 gene
|
US20050101638A1
(en)
*
|
2002-11-08 |
2005-05-12 |
Webb Randy L. |
Combination of organic compounds
|
US20030135663A1
(en)
*
|
2002-01-16 |
2003-07-17 |
Sun Microsystems, Inc. |
Method, system, and program for including device parameters from a device driver in a configuration file
|
PL371678A1
(en)
|
2002-02-13 |
2005-06-27 |
F.Hoffmann-La Roche Ag |
Novel pyridin- and pyrimidin-derivatives
|
CA2474460C
(en)
|
2002-02-13 |
2009-12-22 |
F. Hoffmann-La Roche Ag |
Pyridine- and quinoline-derivatives
|
US7074798B2
(en)
|
2002-02-25 |
2006-07-11 |
Eisai Co., Ltd |
Xanthine derivative and DPPIV inhibitor
|
AU2003225916A1
(en)
*
|
2002-03-25 |
2003-10-13 |
Merck & Co., Inc. |
Beta-amino heterocyclic dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
|
DK1513519T3
(da)
*
|
2002-06-03 |
2009-06-02 |
Novartis Ag |
Anvendelse af substituerede cyanopyrrolidiner til behandling af hyperlipidæmi
|
US6710040B1
(en)
*
|
2002-06-04 |
2004-03-23 |
Pfizer Inc. |
Fluorinated cyclic amides as dipeptidyl peptidase IV inhibitors
|
JP2004026678A
(ja)
*
|
2002-06-24 |
2004-01-29 |
Microbial Chem Res Found |
2型糖尿病治療剤
|
WO2004007446A1
(ja)
*
|
2002-07-10 |
2004-01-22 |
Yamanouchi Pharmaceutical Co., Ltd. |
新規なアゼチジン誘導体又はその塩
|
WO2004007468A1
(en)
|
2002-07-15 |
2004-01-22 |
Merck & Co., Inc. |
Piperidino pyrimidine dipeptidyl peptidase inhibitors for the treatment of diabetes
|
TW200401635A
(en)
*
|
2002-07-23 |
2004-02-01 |
Yamanouchi Pharma Co Ltd |
2-Cyano-4-fluoropyrrolidine derivative or salt thereof
|
US7407955B2
(en)
|
2002-08-21 |
2008-08-05 |
Boehringer Ingelheim Pharma Gmbh & Co., Kg |
8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
|
KR101072236B1
(ko)
*
|
2002-09-19 |
2011-10-12 |
아보트 러보러터리즈 |
디펩티딜 펩티다제-iv(dpp-iv)의 억제제로서의약제학적 조성물
|
WO2004032836A2
(en)
*
|
2002-10-07 |
2004-04-22 |
Merck & Co., Inc. |
Antidiabetic beta-amino heterocylcic dipeptidyl peptidase inhibitors
|
JP4352001B2
(ja)
*
|
2002-10-18 |
2009-10-28 |
メルク エンド カムパニー インコーポレーテッド |
糖尿病の治療または予防のためのベータ−アミノ複素環式ジペプチジルペプチダーゼ阻害剤
|
RU2005117383A
(ru)
|
2002-11-07 |
2006-01-20 |
Мерк энд Ко., Инк. (US) |
Производные фенилаланина в качестве ингибиторов дипептидилпептидазы для лечения или профилактики диабета
|
CA2508487A1
(en)
*
|
2002-12-04 |
2004-06-17 |
Merck & Co., Inc. |
Phenylalanine derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
|
JP4504924B2
(ja)
*
|
2002-12-20 |
2010-07-14 |
メルク・シャープ・エンド・ドーム・コーポレイション |
糖尿病の治療および予防のためのジペプチジルペプチダーゼ阻害薬としての3−アミノ−4−フェニルブタン酸誘導体
|
EP1599468B1
(de)
|
2003-01-14 |
2007-10-03 |
Arena Pharmaceuticals, Inc. |
1,2,3-trisubstituierte aryl- und heteroarylderivate als modulatoren des metabolismus zur vorbeugung und behandlung von metabolismus-bedingten krankheiten wie diabetes oder hyperglykämie
|
US7265128B2
(en)
|
2003-01-17 |
2007-09-04 |
Merck & Co., Inc. |
3-amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
|
US7388019B2
(en)
|
2003-01-31 |
2008-06-17 |
Merck & Co., Inc. |
3-amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
|
CN1894234A
(zh)
|
2003-03-25 |
2007-01-10 |
武田药品工业株式会社 |
二肽基肽酶抑制剂
|
AR044019A1
(es)
*
|
2003-04-16 |
2005-08-24 |
Novartis Ag |
Proceso para la preparacion de 2-cianopirrolidinas n-sustituidas
|
GB0308854D0
(en)
*
|
2003-04-16 |
2003-05-21 |
Novartis Ag |
Organic compounds
|
CA2524531A1
(en)
*
|
2003-05-14 |
2004-12-02 |
Merck And Co., Inc. |
3-amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
|
EP1625122A1
(de)
|
2003-05-14 |
2006-02-15 |
Takeda San Diego, Inc. |
Dipeptidylpeptidase-hemmer
|
CA2526770A1
(en)
*
|
2003-06-06 |
2004-12-23 |
Merck & Co., Inc. |
Fused indoles as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
|
CA2527806A1
(en)
*
|
2003-06-17 |
2004-12-29 |
Merck & Co., Inc. |
Cyclohexylglycine derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
|
DE602004030244D1
(de)
|
2003-06-20 |
2011-01-05 |
Hoffmann La Roche |
Itoren
|
MXPA05013734A
(es)
|
2003-06-20 |
2006-03-08 |
Hoffmann La Roche |
Hexahidropiroisoquinolinas como inhibidores de dpp-iv.
|
DE602004018503D1
(de)
|
2003-07-31 |
2009-01-29 |
Merck & Co Inc |
Hexahydrodiazepinone als inhibitoren des dipeptidylpeptidase-iv zur behandlung bzw. prävention von diabetes
|
US6995183B2
(en)
|
2003-08-01 |
2006-02-07 |
Bristol Myers Squibb Company |
Adamantylglycine-based inhibitors of dipeptidyl peptidase IV and methods
|
US7169926B1
(en)
|
2003-08-13 |
2007-01-30 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors
|
US7678909B1
(en)
|
2003-08-13 |
2010-03-16 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors
|
MXPA06001601A
(es)
|
2003-08-13 |
2006-08-25 |
Takeda Pharmaceutical |
Derivados de 4-pirimidona y su uso como inhibidores de dipeptidilpeptidasa.
|
WO2005026148A1
(en)
|
2003-09-08 |
2005-03-24 |
Takeda San Diego, Inc. |
Dipeptidyl peptidase inhibitors
|
WO2005025554A2
(en)
*
|
2003-09-09 |
2005-03-24 |
Japan Tobacco Inc. |
Dipeptidyl peptidase iv inhibitor
|
WO2005033099A2
(en)
*
|
2003-10-03 |
2005-04-14 |
Glenmark Pharmaceuticals Ltd. |
Novel dipeptidyl peptidase iv inhibitors; processes for their preparation and compositions thereof
|
EP1680120A2
(de)
*
|
2003-11-03 |
2006-07-19 |
Probiodrug AG |
Zusammenstellungen zur behandlung von neuronalen erkrankungen
|
US7238683B2
(en)
*
|
2003-11-04 |
2007-07-03 |
Merck & Co., Inc. |
Fused phenylalanine derivatives as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
|
US7767828B2
(en)
*
|
2003-11-12 |
2010-08-03 |
Phenomix Corporation |
Methyl and ethyl substituted pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
|
US7576121B2
(en)
*
|
2003-11-12 |
2009-08-18 |
Phenomix Corporation |
Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
|
EP1997533B8
(de)
*
|
2003-11-12 |
2014-10-29 |
Sino-Med International Alliance, Inc. |
Heterocyclische Boronsäureverbindungen, Dipeptidylpeptidase IV Inhibitoren
|
US7317109B2
(en)
|
2003-11-12 |
2008-01-08 |
Phenomix Corporation |
Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
|
KR20140089408A
(ko)
|
2003-11-17 |
2014-07-14 |
노파르티스 아게 |
디펩티딜 펩티다제 ⅳ 억제제의 용도
|
PT1715893E
(pt)
*
|
2004-01-20 |
2009-10-20 |
Novartis Pharma Ag |
Formulação para compressão directa e processos
|
KR101130433B1
(ko)
*
|
2004-02-05 |
2012-03-27 |
교린 세이야꾸 가부시키 가이샤 |
비시클로에스테르 유도체
|
US7501426B2
(en)
|
2004-02-18 |
2009-03-10 |
Boehringer Ingelheim International Gmbh |
8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions
|
EP1717225A4
(de)
*
|
2004-02-18 |
2009-10-21 |
Kyorin Seiyaku Kk |
Bicyclische amidderivate
|
EP1732550A2
(de)
*
|
2004-02-20 |
2006-12-20 |
Novartis AG |
Dpp-iv-inhibitoren zur behandlung neurodegenerativer und kognitiver erkrankungen
|
EP1719757B1
(de)
*
|
2004-02-27 |
2013-10-09 |
Kyorin Pharmaceutical Co., Ltd. |
Bicycloderivate
|
CN1942186B
(zh)
*
|
2004-03-09 |
2010-10-06 |
国家卫生研究院 |
吡咯烷化合物
|
US7732446B1
(en)
|
2004-03-11 |
2010-06-08 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors
|
CN102079743B
(zh)
|
2004-03-15 |
2020-08-25 |
武田药品工业株式会社 |
二肽基肽酶抑制剂
|
TW200604167A
(en)
*
|
2004-04-27 |
2006-02-01 |
Astellas Pharma Inc |
Pyrrolidine derivatives
|
WO2005108382A1
(en)
|
2004-05-04 |
2005-11-17 |
Merck & Co., Inc. |
1,2,4-oxadiazole derivatives as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
|
WO2005116029A1
(en)
*
|
2004-05-18 |
2005-12-08 |
Merck & Co., Inc. |
Cyclohexylalanine derivatives as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
|
US7935723B2
(en)
*
|
2004-06-04 |
2011-05-03 |
Novartis Pharma Ag |
Use of organic compounds
|
WO2005118555A1
(en)
|
2004-06-04 |
2005-12-15 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors
|
EP1778220A1
(de)
|
2004-07-12 |
2007-05-02 |
Phenomix Corporation |
Eingezwängte cyano-verbindungen
|
WO2006019965A2
(en)
|
2004-07-16 |
2006-02-23 |
Takeda San Diego, Inc. |
Dipeptidyl peptidase inhibitors
|
JP2008507541A
(ja)
*
|
2004-07-23 |
2008-03-13 |
ロイヤルティ,スーザン・マリー |
ペプチダーゼ阻害剤
|
TW200608967A
(en)
|
2004-07-29 |
2006-03-16 |
Sankyo Co |
Pharmaceutical compositions containing with diabetic agent
|
PE20060652A1
(es)
|
2004-08-27 |
2006-08-11 |
Novartis Ag |
Composiciones farmaceuticas de liberacion inmediata que comprenden granulos de fusion
|
EA013463B1
(ru)
|
2004-10-12 |
2010-04-30 |
ГЛЕНМАРК ФАРМАСЬЮТИКАЛС Эс.Эй. |
Новые ингибиторы дипептидилпептидазы iv, содержащие их фармацевтические композиции, способ их получения и способ лечения с их применением
|
MX2007004934A
(es)
*
|
2004-10-25 |
2007-06-12 |
Novartis Ag |
Combinacion de inhibidor de dpp-iv, anti-diabetico de ppar, y metformina.
|
DE102004054054A1
(de)
|
2004-11-05 |
2006-05-11 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine
|
US7411093B2
(en)
|
2004-12-20 |
2008-08-12 |
Hoffman-La Roche Inc. |
Aminocycloalkanes as DPP-IV inhibitors
|
KR100904829B1
(ko)
|
2004-12-20 |
2009-06-25 |
에프. 호프만-라 로슈 아게 |
4-아미노피페리딘 유도체
|
WO2006068978A2
(en)
|
2004-12-21 |
2006-06-29 |
Takeda Pharmaceutial Company Limited |
Dipeptidyl peptidase inhibitors
|
DOP2006000008A
(es)
|
2005-01-10 |
2006-08-31 |
Arena Pharm Inc |
Terapia combinada para el tratamiento de la diabetes y afecciones relacionadas y para el tratamiento de afecciones que mejoran mediante un incremento de la concentración sanguínea de glp-1
|
GT200600008A
(es)
*
|
2005-01-18 |
2006-08-09 |
|
Formulacion de compresion directa y proceso
|
JP2008024592A
(ja)
*
|
2005-01-28 |
2008-02-07 |
Taisho Pharmaceut Co Ltd |
シアノピロリジン誘導体含有固形製剤用組成物、それを含有する固形製剤及びその製造方法
|
WO2006090244A1
(en)
*
|
2005-02-22 |
2006-08-31 |
Glenmark Pharmaceuticals S.A. |
New adamantane derivatives as dipeptidyl, peptidase iv inhibitors, processes for their preparation, and pharmaceutical compositions containing them
|
TWI357902B
(en)
|
2005-04-01 |
2012-02-11 |
Lg Life Science Ltd |
Dipeptidyl peptidase-iv inhibiting compounds, meth
|
AU2006239929B2
(en)
*
|
2005-04-22 |
2011-11-03 |
Alantos Pharmaceuticals Holding, Inc. |
Dipeptidyl peptidase-IV inhibitors
|
US7825139B2
(en)
|
2005-05-25 |
2010-11-02 |
Forest Laboratories Holdings Limited (BM) |
Compounds and methods for selective inhibition of dipeptidyl peptidase-IV
|
AU2006255097B2
(en)
|
2005-06-06 |
2012-02-09 |
Georgetown University |
Compositions and methods for lipo modeling
|
MY152185A
(en)
|
2005-06-10 |
2014-08-29 |
Novartis Ag |
Modified release 1-[(3-hydroxy-adamant-1-ylamino)-acetyl]-pyrrolidine-2(s)-carbonitrile formulation
|
EP1912706A4
(de)
*
|
2005-06-17 |
2009-05-27 |
Aurigene Discovery Technologie |
Neue 5-substituierte indol-derivate als dipeptidyl-peptidase iv (dpp-iv) hemmer
|
KR20080028422A
(ko)
*
|
2005-07-12 |
2008-03-31 |
노파르티스 아게 |
Dpp-iv 억제제 및 칸나비노이드 cb1 수용체길항제의 배합물
|
DE102005035891A1
(de)
|
2005-07-30 |
2007-02-08 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
8-(3-Amino-piperidin-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
|
BRPI0614610A2
(pt)
*
|
2005-08-04 |
2011-04-05 |
Novartis Ag |
compostos
|
GT200600381A
(es)
|
2005-08-25 |
2007-03-28 |
|
Compuestos organicos
|
WO2007033350A1
(en)
|
2005-09-14 |
2007-03-22 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors for treating diabetes
|
EP1924567B1
(de)
|
2005-09-16 |
2012-08-22 |
Takeda Pharmaceutical Company Limited |
Verfahren zur herstellung von pyrimidindionderivaten
|
JOP20180109A1
(ar)
*
|
2005-09-29 |
2019-01-30 |
Novartis Ag |
تركيبة جديدة
|
TW200738266A
(en)
*
|
2005-09-29 |
2007-10-16 |
Sankyo Co |
Pharmaceutical agent containing insulin resistance improving agent
|
CN101365476A
(zh)
*
|
2005-10-07 |
2009-02-11 |
瓦拉塔药品公司 |
Dpp-iv抑制剂和胃泌素化合物的联合使用
|
GB0526291D0
(en)
|
2005-12-23 |
2006-02-01 |
Prosidion Ltd |
Therapeutic method
|
US20090054512A1
(en)
*
|
2006-01-06 |
2009-02-26 |
Foley James E |
Use of organic compounds
|
CN101395131B
(zh)
|
2006-03-08 |
2012-11-14 |
杏林制药株式会社 |
氨基乙酰基吡咯烷甲腈衍生物的制备方法及其制备中间体
|
AU2007227202B2
(en)
|
2006-03-21 |
2013-08-22 |
Amylin Pharmaceuticals, Llc |
Peptide-peptidase inhibitor conjugates and methods of using same
|
WO2007112347A1
(en)
|
2006-03-28 |
2007-10-04 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors
|
EP2004601B1
(de)
*
|
2006-04-03 |
2011-03-02 |
Matrix Laboratories Limited |
Neue dipeptidylpeptidase-iv-inhibitoren und verfahren zur ihrer herstellung und pharmazeutische zusammensetzung, die diese enthalten
|
DE602007012845D1
(de)
*
|
2006-04-03 |
2011-04-14 |
Matrix Lab Ltd |
Neue dipeptidylpeptidase-iv-inhibitoren und verfahren zur ihrer herstellung und pharmazeutische zusammensetzung, die diese enthalten
|
AR060406A1
(es)
|
2006-04-11 |
2008-06-11 |
Arena Pharm Inc |
Metodos para usar el receptor gpr119 en la identificacion de compuestos utiles para aumentar la masa osea en un individuo
|
PE20071221A1
(es)
|
2006-04-11 |
2007-12-14 |
Arena Pharm Inc |
Agonistas del receptor gpr119 en metodos para aumentar la masa osea y para tratar la osteoporosis y otras afecciones caracterizadas por masa osea baja, y la terapia combinada relacionada a estos agonistas
|
EP1852108A1
(de)
|
2006-05-04 |
2007-11-07 |
Boehringer Ingelheim Pharma GmbH & Co.KG |
Zusammensetzungen von DPP-IV-Inhibitoren
|
PE20080251A1
(es)
|
2006-05-04 |
2008-04-25 |
Boehringer Ingelheim Int |
Usos de inhibidores de dpp iv
|
MX2008014024A
(es)
|
2006-05-04 |
2008-11-14 |
Boehringer Ingelheim Int |
Formas poliformas.
|
JP2009538356A
(ja)
|
2006-05-26 |
2009-11-05 |
アミリン・ファーマシューティカルズ,インコーポレイテッド |
鬱血性心不全の治療のための組成物および方法
|
US20100179131A1
(en)
|
2006-09-07 |
2010-07-15 |
Nycomed Gmbh |
Combination treatment for diabetes mellitus
|
CA2663279C
(en)
*
|
2006-09-13 |
2016-05-17 |
Takeda Pharmaceutical Company Limited |
Use of 2-6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2h-pyrimidin-1-ylmethyl-4-fluoro-benzonitrile for treating diabetes, cancer, autoimmune disorders and hiv infection
|
US8324383B2
(en)
|
2006-09-13 |
2012-12-04 |
Takeda Pharmaceutical Company Limited |
Methods of making polymorphs of benzoate salt of 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-benzonitrile
|
TW200838536A
(en)
|
2006-11-29 |
2008-10-01 |
Takeda Pharmaceutical |
Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor
|
WO2008084383A2
(en)
*
|
2007-01-10 |
2008-07-17 |
Medichem, S.A. |
Process for preparing vildagliptin
|
US8093236B2
(en)
|
2007-03-13 |
2012-01-10 |
Takeda Pharmaceuticals Company Limited |
Weekly administration of dipeptidyl peptidase inhibitors
|
US20080064701A1
(en)
*
|
2007-04-24 |
2008-03-13 |
Ramesh Sesha |
Anti-diabetic combinations
|
JPWO2008114857A1
(ja)
|
2007-03-22 |
2010-07-08 |
杏林製薬株式会社 |
アミノアセチルピロリジンカルボニトリル誘導体の製造方法
|
EP2143443B1
(de)
|
2007-04-03 |
2014-11-19 |
Mitsubishi Tanabe Pharma Corporation |
Eine kombination eines dipeptidyl-peptidase-iv-inhibitors und eines süssstoffs zur behandlung der adipositas
|
DE102007022007A1
(de)
*
|
2007-05-08 |
2008-11-13 |
Schebo Biotech Ag |
Neuartike Pharmazeutika, Verfahren zu ihrer Herstellung und ihre Verwendung in der Prophylaxe und Therapie von ZNS-Erkrankungen und Diabetes
|
PT2152663E
(pt)
|
2007-06-04 |
2014-06-03 |
Univ Ben Gurion |
Compostos de triarilo e composições que compreendem os mesmos
|
CL2008002427A1
(es)
|
2007-08-16 |
2009-09-11 |
Boehringer Ingelheim Int |
Composicion farmaceutica que comprende 1-cloro-4-(b-d-glucopiranos-1-il)-2-[4-((s)-tetrahidrofurano-3-iloxi)bencil]-benceno combinado con 1-[(4-metilquinazolin-2-il)metil]-3-metil-7-(2-butin-1-il)-8-(3-(r)-aminopiperidin-1-il)xantina; y su uso para tratar diabetes mellitus tipo 2.
|
US20110112069A1
(en)
*
|
2007-08-17 |
2011-05-12 |
Boehringer Ingelheim International Gmbh |
Purin derivatives for use in the treatment of fab-related diseases
|
WO2009037719A1
(en)
*
|
2007-09-21 |
2009-03-26 |
Lupin Limited |
Novel compounds as dipeptidyl peptidase iv (dpp iv) inhibitors
|
US20090082420A1
(en)
*
|
2007-09-25 |
2009-03-26 |
Protia, Llc |
Deuterium-enriched vildagliptin
|
US8598314B2
(en)
*
|
2007-09-27 |
2013-12-03 |
Amylin Pharmaceuticals, Llc |
Peptide-peptidase-inhibitor conjugates and methods of making and using same
|
PT2247602E
(pt)
*
|
2007-11-30 |
2013-07-10 |
Novartis Ag |
Derivados de adamantil o-glucuronido como inibidores da dipeptidilpeptidase iv para o tratamento de diabetes
|
JP2011506421A
(ja)
*
|
2007-12-12 |
2011-03-03 |
アストラゼネカ・アクチエボラーグ |
ペプチジルニトリル類およびジペプチジルペプチダーゼi阻害剤としてのその使用
|
BRPI0819719B8
(pt)
|
2007-12-21 |
2021-05-25 |
Lg Chemical Ltd |
compostos de inibição de dipeptidil peptidase-iv, métodos de preparação dos mesmos, e preparações farmacêuticas contendo os mesmos como agente ativo
|
CL2008003653A1
(es)
|
2008-01-17 |
2010-03-05 |
Mitsubishi Tanabe Pharma Corp |
Uso de un inhibidor de sglt derivado de glucopiranosilo y un inhibidor de dppiv seleccionado para tratar la diabetes; y composicion farmaceutica.
|
US8551524B2
(en)
*
|
2008-03-14 |
2013-10-08 |
Iycus, Llc |
Anti-diabetic combinations
|
PE20091730A1
(es)
|
2008-04-03 |
2009-12-10 |
Boehringer Ingelheim Int |
Formulaciones que comprenden un inhibidor de dpp4
|
EP2146210A1
(de)
|
2008-04-07 |
2010-01-20 |
Arena Pharmaceuticals, Inc. |
Verfahren zur Verwendung eines AG-Protein-gekoppelten Rezeptors zur Identifikation von Peptid-YY (PPY)-Sekretagogen sowie Verbindungen zur Behandlung durch PYY modulierter Leiden
|
PE20100156A1
(es)
*
|
2008-06-03 |
2010-02-23 |
Boehringer Ingelheim Int |
Tratamiento de nafld
|
WO2009155309A1
(en)
*
|
2008-06-19 |
2009-12-23 |
Concert Pharmaceuticals, Inc. |
Substituted cyanopyrrolidine derivatives
|
BRPI0916997A2
(pt)
|
2008-08-06 |
2020-12-15 |
Boehringer Ingelheim International Gmbh |
Inibidor de dpp-4 e seu uso
|
UY32030A
(es)
|
2008-08-06 |
2010-03-26 |
Boehringer Ingelheim Int |
"tratamiento para diabetes en pacientes inapropiados para terapia con metformina"
|
CA2732984A1
(en)
|
2008-08-07 |
2010-02-11 |
Kyorin Pharmaceutical Co., Ltd. |
Process for production of bicyclo[2.2.2]octylamine derivative
|
CN102186474A
(zh)
*
|
2008-08-14 |
2011-09-14 |
杏林制药株式会社 |
稳定的医药组合物
|
WO2010018217A2
(en)
|
2008-08-15 |
2010-02-18 |
Boehringer Ingelheim International Gmbh |
Organic compounds for wound healing
|
CZ2008512A3
(cs)
*
|
2008-08-26 |
2010-03-10 |
Zentiva, A. S |
Zpusob prípravy vysoce cistého vildagliptinu
|
US8513264B2
(en)
|
2008-09-10 |
2013-08-20 |
Boehringer Ingelheim International Gmbh |
Combination therapy for the treatment of diabetes and related conditions
|
CN102850330B
(zh)
*
|
2008-09-23 |
2014-10-15 |
成都地奥制药集团有限公司 |
经溴代的制备n取代的吡咯烷衍生物的方法
|
US20200155558A1
(en)
|
2018-11-20 |
2020-05-21 |
Boehringer Ingelheim International Gmbh |
Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug
|
JO2870B1
(en)
|
2008-11-13 |
2015-03-15 |
ميرك شارب اند دوهم كورب |
Amino Tetra Hydro Pirans as Inhibitors of Peptide Dipeptide IV for the Treatment or Prevention of Diabetes
|
CN107011345A
(zh)
|
2008-12-23 |
2017-08-04 |
勃林格殷格翰国际有限公司 |
有机化合物的盐形式
|
AR074990A1
(es)
|
2009-01-07 |
2011-03-02 |
Boehringer Ingelheim Int |
Tratamiento de diabetes en pacientes con un control glucemico inadecuado a pesar de la terapia con metformina
|
KR101750420B1
(ko)
|
2009-01-09 |
2017-06-26 |
오키드 파마 리미티드 |
디펩티딜 펩티다제 iv 억제제
|
TWI466672B
(zh)
|
2009-01-29 |
2015-01-01 |
Boehringer Ingelheim Int |
小兒科病人糖尿病之治療
|
EA029759B1
(ru)
|
2009-02-13 |
2018-05-31 |
Бёрингер Ингельхайм Интернациональ Гмбх |
Антидиабетические лекарственные средства, содержащие ингибитор dpp-4 (линаглиптин) необязательно в комбинации с другими антидиабетическими средствами
|
AU2010212867B2
(en)
|
2009-02-13 |
2013-05-16 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical composition comprising a SGLT2 inhibitor, a DPP-IV inhibitor and optionally a further antidiabetic agent and uses thereof
|
RU2011142829A
(ru)
|
2009-03-27 |
2013-05-10 |
Киорин Фармасьютикал Ко., Лтд. |
Препарат матричного типа с пролонгированным высвобождением, содержащий базисную добавку
|
CN102574830A
(zh)
|
2009-05-07 |
2012-07-11 |
阿斯利康(瑞典)有限公司 |
取代的1-氰基乙基杂环基甲酰胺化合物750
|
KR20120036850A
(ko)
|
2009-05-15 |
2012-04-18 |
노파르티스 아게 |
알도스테론 신타제 억제제로서의 벤족사졸론 유도체
|
MA33358B1
(fr)
|
2009-05-15 |
2012-06-01 |
Novartis Ag |
Arylpyridine en tant qu'inhibiteurs de l'aldostérone synthase
|
KR101442897B1
(ko)
|
2009-05-28 |
2014-09-23 |
노파르티스 아게 |
네프릴리신 억제제로서의 치환된 아미노프로피온산 유도체
|
AR076706A1
(es)
|
2009-05-28 |
2011-06-29 |
Novartis Ag |
Derivados aminobutiricos sustituidos como inhibidores de neprilisina
|
GB2483614B
(en)
|
2009-06-18 |
2014-12-03 |
Lupin Ltd |
2-Amino-2- [8-(dimethyl carbamoyl)- 8-aza- bicyclo [3.2.1] oct-3-yl]-exo- ethanoyl derivatives as potent dpp-iv inhibitors
|
AR077642A1
(es)
|
2009-07-09 |
2011-09-14 |
Arena Pharm Inc |
Moduladores del metabolismo y el tratamiento de trastornos relacionados con el mismo
|
WO2011014520A2
(en)
|
2009-07-29 |
2011-02-03 |
Irm Llc |
Compounds and compositions as modulators of gpr119 activity
|
EA034049B1
(ru)
|
2009-07-31 |
2019-12-23 |
КРКА, д.д., НОВО МЕСТО |
Гранулят, включающий вилдаглиптин, способ его получения и фармацевтическая композиция
|
WO2011028455A1
(en)
|
2009-09-02 |
2011-03-10 |
Merck Sharp & Dohme Corp. |
Aminotetrahydropyrans as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
|
AU2010289397B2
(en)
|
2009-09-03 |
2016-05-26 |
Bioenergenix |
Heterocyclic compounds for the inhibition of PASK
|
EP2295083A1
(de)
|
2009-09-15 |
2011-03-16 |
Ratiopharm GmbH |
Pharmazeutische Zusammensetzung mit den Wirkstoffen Metformin und Sitagliptin oder Vildagliptin
|
EP2477985B1
(de)
|
2009-09-15 |
2018-11-07 |
BlueLink Pharmaceuticals, Inc. |
Crlx101 zur verwendung bei der krebsbehandlung
|
HUP0900638A2
(en)
|
2009-10-07 |
2011-05-30 |
Egyt Gyogyszervegyeszeti Gyar |
Adducts of inorganic salts basea on vildaelitpin applicable for preparation of pharmaceutical compositions
|
EP2308847B1
(de)
|
2009-10-09 |
2014-04-02 |
EMC microcollections GmbH |
Substituierte Pyridine als Inhibitoren der Dipeptidyl Peptidase IV und ihre Anwendung für die Behandlung von Diabetes und verwandten Krankheiten
|
US8575168B2
(en)
|
2009-10-09 |
2013-11-05 |
Irm Llc |
Compounds and compositions as modulators of GPR119 activity
|
JP5654608B2
(ja)
|
2009-11-17 |
2015-01-14 |
ノバルティス アーゲー |
アルドステロンシンターゼ阻害剤としてのアリール−ピリジン誘導体
|
JO2967B1
(en)
|
2009-11-20 |
2016-03-15 |
نوفارتس ايه جي |
Acetic acid derivatives of carbamoyl methyl amino are substituted as new NEP inhibitors
|
CN102781237A
(zh)
|
2009-11-23 |
2012-11-14 |
天蓝制药公司 |
用于传递治疗剂的基于环糊精的聚合物
|
EP3646859A1
(de)
|
2009-11-27 |
2020-05-06 |
Boehringer Ingelheim International GmbH |
Behandlung von genotypisierten diabetes-patienten mit dpp-iv-hemmern wie etwa linagliptin
|
WO2011064376A1
(en)
|
2009-11-30 |
2011-06-03 |
Novartis Ag |
Imidazole derivatives as aldosterone synthase inhibitors
|
US8394858B2
(en)
|
2009-12-03 |
2013-03-12 |
Novartis Ag |
Cyclohexane derivatives and uses thereof
|
EP2518051A4
(de)
|
2009-12-22 |
2013-10-16 |
Shionogi & Co |
Adamantanaminderivate
|
US20110178287A1
(en)
|
2010-01-19 |
2011-07-21 |
Cerulean Pharma Inc. |
Cyclodextrin-based polymers for therapeutic delivery
|
WO2011103256A1
(en)
|
2010-02-22 |
2011-08-25 |
Merck Sharp & Dohme Corp. |
Substituted aminotetrahydrothiopyrans and derivatives thereof as dipeptidyl peptidase-iv inhibitors for the treatment of diabetes
|
CN101798270B
(zh)
*
|
2010-02-25 |
2013-04-17 |
东华大学 |
一种3-氨基-1-金刚烷醇的制备方法
|
US20130109703A1
(en)
|
2010-03-18 |
2013-05-02 |
Boehringer Ingelheim International Gmbh |
Combination of a GPR119 Agonist and the DPP-IV Inhibitor Linagliptin for Use in the Treatment of Diabetes and Related Conditions
|
CN102918027A
(zh)
|
2010-04-06 |
2013-02-06 |
艾尼纳制药公司 |
Gpr119受体调节剂和对与所述受体有关的障碍的治疗
|
AU2011249722B2
(en)
|
2010-05-05 |
2015-09-17 |
Boehringer Ingelheim International Gmbh |
Combination therapy
|
EP2571876B1
(de)
|
2010-05-21 |
2016-09-07 |
Merck Sharp & Dohme Corp. |
Substituierte siebenteilige heterozyklische verbindungen als dipeptidyl-peptidase-iv-hemmer zur behandlung von diabetes
|
CN102260265B
(zh)
|
2010-05-24 |
2015-09-02 |
上海阳帆医药科技有限公司 |
六氢吡咯[3,4-b]吡咯衍生物、其制备方法及其用途
|
CN101870671B
(zh)
*
|
2010-06-11 |
2012-06-27 |
漆又毛 |
金刚烷基吡咯烷衍生物及制备和应用
|
BR112012032579B1
(pt)
|
2010-06-24 |
2021-05-11 |
Boehringer Ingelheim International Gmbh |
uso de linagliptina e composição farmacêutica compreendendo linagliptina e insulina basal de longa duração
|
IT1400714B1
(it)
|
2010-07-06 |
2013-06-28 |
Chemelectiva S R L |
Processo ed intermedi per la preparazione di un principio attivo.
|
US8697739B2
(en)
|
2010-07-29 |
2014-04-15 |
Novartis Ag |
Bicyclic acetyl-CoA carboxylase inhibitors and uses thereof
|
CN103209957A
(zh)
*
|
2010-08-09 |
2013-07-17 |
盐野义制药株式会社 |
氨基金刚烷氨基甲酸酯衍生物的制备方法
|
HU231050B1
(hu)
|
2010-08-19 |
2020-02-28 |
Egis Gyógyszergyár Nyrt. |
Eljárás gyógyszerhatóanyag előállítására
|
AU2011305525B2
(en)
|
2010-09-22 |
2016-08-18 |
Arena Pharmaceuticals, Inc. |
Modulators of the GPR119 receptor and the treatment of disorders related thereto
|
US9034883B2
(en)
|
2010-11-15 |
2015-05-19 |
Boehringer Ingelheim International Gmbh |
Vasoprotective and cardioprotective antidiabetic therapy
|
US8673974B2
(en)
|
2010-11-16 |
2014-03-18 |
Novartis Ag |
Substituted amino bisphenyl pentanoic acid derivatives as NEP inhibitors
|
US8877815B2
(en)
|
2010-11-16 |
2014-11-04 |
Novartis Ag |
Substituted carbamoylcycloalkyl acetic acid derivatives as NEP
|
TR201010683A1
(tr)
|
2010-12-21 |
2012-07-23 |
Sanovel İlaç San. Ve Ti̇c. A.Ş. |
Vildagliptin formülasyonları.
|
EP2468268B1
(de)
|
2010-12-21 |
2017-12-13 |
Sanovel Ilaç Sanayi Ve Ticaret Anonim Sirketi |
Kombinationszusammensetzung aus Vildagliptin und Gliclazid
|
TR201101809A1
(tr)
|
2010-12-21 |
2012-07-23 |
Sanovel İlaç Sanayi̇ Ve Ti̇caret Anoni̇m Şi̇rketi̇ |
Vildagliptin ve glimepirid kombinasyonları.
|
TR201107482A1
(tr)
|
2010-12-21 |
2012-07-23 |
Sanovel İlaç San.Ve Ti̇c.A.Ş. |
Vildagliptin ve gliklazidin iki tabakalı kombinasyon kompozisyonu.
|
EP3009136A1
(de)
|
2011-01-31 |
2016-04-20 |
Cadila Healthcare Limited |
Behandlung von lipodystrophie
|
WO2012119046A2
(en)
|
2011-03-02 |
2012-09-07 |
Bioenergenix |
Heterocyclic compounds for the inhibition of pask
|
US20140018371A1
(en)
|
2011-04-01 |
2014-01-16 |
Arena Pharmaceuticals, Inc. |
Modulators Of The GPR119 Receptor And The Treatment Of Disorders Related Thereto
|
US20140066369A1
(en)
|
2011-04-19 |
2014-03-06 |
Arena Pharmaceuticals, Inc. |
Modulators Of The GPR119 Receptor And The Treatment Of Disorders Related Thereto
|
WO2012145604A1
(en)
|
2011-04-22 |
2012-10-26 |
Arena Pharmaceuticals, Inc. |
Modulators of the gpr119 receptor and the treatment of disorders related thereto
|
WO2012145603A1
(en)
|
2011-04-22 |
2012-10-26 |
Arena Pharmaceuticals, Inc. |
Modulators of the gpr119 receptor and the treatment of disorders related thereto
|
WO2012170702A1
(en)
|
2011-06-08 |
2012-12-13 |
Arena Pharmaceuticals, Inc. |
Modulators of the gpr119 receptor and the treatment of disorders related thereto
|
WO2013006526A2
(en)
|
2011-07-05 |
2013-01-10 |
Merck Sharp & Dohme Corp. |
Tricyclic heterocycles useful as dipeptidyl peptidase-iv inhibitors
|
HUE043540T2
(hu)
|
2011-07-15 |
2019-08-28 |
Boehringer Ingelheim Int |
Szubsztituált dimer kinazolin-származék, elõállítása, valamint alkalmazása 1-es és 2-es típusú cukorbetegség kezelésére szolgáló gyógyászati készítményekben
|
EA201490556A1
(ru)
|
2011-09-07 |
2014-08-29 |
Сановел Илач Санайи Ве Тиджарет Аноним Ширкети |
Составы ингибитора дпп-4
|
EP2572704A1
(de)
|
2011-09-22 |
2013-03-27 |
Sanovel Ilac Sanayi ve Ticaret A.S. |
Im Mund zerfallende Formulierungen mit Vildagliptin
|
PL2578208T3
(pl)
|
2011-10-06 |
2014-10-31 |
Sanovel Ilac Sanayi Ve Ticaret As |
Stałe formulacje dawkowane inhibitora DPP-IV
|
WO2013055910A1
(en)
|
2011-10-12 |
2013-04-18 |
Arena Pharmaceuticals, Inc. |
Modulators of the gpr119 receptor and the treatment of disorders related thereto
|
ITMI20112224A1
(it)
|
2011-12-06 |
2013-06-07 |
Chemelectiva S R L |
Nuovo processo ed intermedi per la sintesi di vildagliptin
|
CN102491928A
(zh)
*
|
2011-12-13 |
2012-06-13 |
临海天宇药业有限公司 |
一种制备(2s)-n-氯乙酰基-2-氰基四氢吡咯的方法
|
US9115082B2
(en)
|
2012-01-18 |
2015-08-25 |
Catherine Yang |
Dipeptidyl-peptidase-IV inhibitors for treatment of type 2 diabetes complex with hypertension
|
WO2013122920A1
(en)
|
2012-02-17 |
2013-08-22 |
Merck Sharp & Dohme Corp. |
Dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
|
US9555001B2
(en)
|
2012-03-07 |
2017-01-31 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical composition and uses thereof
|
CN102617434B
(zh)
*
|
2012-03-29 |
2014-07-23 |
中国科学院上海有机化学研究所 |
一锅法制备维达列汀
|
IN2012MU01383A
(de)
|
2012-05-04 |
2014-02-28 |
|
|
EP3685839A1
(de)
|
2012-05-14 |
2020-07-29 |
Boehringer Ingelheim International GmbH |
Linagliptin zur verwendung in der behandlung von albuminuria und nierenbedingten erkrankungen
|
WO2013174767A1
(en)
|
2012-05-24 |
2013-11-28 |
Boehringer Ingelheim International Gmbh |
A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference
|
WO2014018350A1
(en)
|
2012-07-23 |
2014-01-30 |
Merck Sharp & Dohme Corp. |
Treating diabetes with dipeptidyl peptidase-iv inhibitors
|
WO2014020462A1
(en)
*
|
2012-08-01 |
2014-02-06 |
Alembic Pharmaceuticals Limited |
Improved process for preparation of vildagliptin intermediate
|
WO2014052619A1
(en)
|
2012-09-27 |
2014-04-03 |
Irm Llc |
Piperidine derivatives and compositions as modulators of gpr119 activity
|
TWI500613B
(zh)
|
2012-10-17 |
2015-09-21 |
Cadila Healthcare Ltd |
新穎之雜環化合物
|
WO2014074668A1
(en)
|
2012-11-08 |
2014-05-15 |
Arena Pharmaceuticals, Inc. |
Modulators of gpr119 and the treatment of disorders related thereto
|
UY35144A
(es)
|
2012-11-20 |
2014-06-30 |
Novartis Ag |
Miméticos lineales sintéticos de apelina para el tratamiento de insuficiencia cardiaca
|
CN103922986B
(zh)
*
|
2013-01-16 |
2017-02-15 |
上海彩迩文生化科技有限公司 |
维大列汀及其类似物、中间体及其制备方法和应用
|
MX367525B
(es)
|
2013-02-14 |
2019-08-26 |
Novartis Ag |
Derivados de ácido bisfenil-butanoico fosfónico sustituido como inhibidores de la endopeptidasa neutra (nep).
|
UA114360C2
(uk)
|
2013-04-22 |
2017-05-25 |
Каділа Хелткере Лімітед |
Спосіб лікування та/або зменшення інтенсивності неалкогольної жирової хвороби печінки (нжхп)
|
US20160107989A1
(en)
|
2013-05-30 |
2016-04-21 |
Cadila Healthcare Limited |
A process for preparation of pyrroles having hypolipidemic hypocholesteremic activities
|
CN103304502B
(zh)
*
|
2013-06-02 |
2015-03-04 |
张远强 |
一类抗糖尿病化合物、其制备方法和用途
|
TW201636015A
(zh)
|
2013-07-05 |
2016-10-16 |
卡地拉保健有限公司 |
協同性組成物
|
BR112016001376A2
(pt)
|
2013-07-25 |
2017-10-24 |
Novartis Ag |
bioconjugados de polipeptídeos de apelin sintéticos
|
UY35670A
(es)
|
2013-07-25 |
2015-02-27 |
Novartis Ag |
Polipéptidos cíclicos para el tratamiento de insuficiencia cardíaca
|
IN2013MU02470A
(de)
|
2013-07-25 |
2015-06-26 |
Cadila Healthcare Ltd |
|
US10112898B2
(en)
|
2013-09-06 |
2018-10-30 |
Cadila Healthcare Limited |
Process for the preparation of saroglitazar pharmaceutical salts
|
JP6657101B2
(ja)
|
2013-11-05 |
2020-03-04 |
ベン グリオン ユニバーシティ オブ ザ ネガフ リサーチ アンド ディベロップメント オーソリティ |
糖尿病及びそれから生じる疾患合併症の治療のための化合物
|
CN103641761A
(zh)
*
|
2013-11-22 |
2014-03-19 |
沈阳化工大学 |
一种维格利汀的制备方法
|
ES2950384T3
(es)
|
2014-02-28 |
2023-10-09 |
Boehringer Ingelheim Int |
Uso médico de un inhibidor de DPP-4
|
US20170014380A1
(en)
|
2014-03-06 |
2017-01-19 |
Sanovell IIac Sanayi Ve Ticaret Anonim Sirketi |
Vildagliptin Formulation Process Under Inert Gas Atmosphere
|
CN103992257B
(zh)
*
|
2014-05-16 |
2016-03-30 |
苏州天马精细化学品股份有限公司 |
一种维格列汀粗品的纯化方法
|
CN105439873A
(zh)
*
|
2014-08-20 |
2016-03-30 |
天津药物研究院 |
3-羟基-1-金刚烷胺的制备方法
|
GB201415598D0
(en)
|
2014-09-03 |
2014-10-15 |
Univ Birmingham |
Elavated Itercranial Pressure Treatment
|
CN105884669B
(zh)
*
|
2014-09-15 |
2020-05-15 |
深圳翰宇药业股份有限公司 |
制备取代的(s)-吡咯烷-2-甲腈及维格列汀的方法
|
CN116850181A
(zh)
|
2015-01-06 |
2023-10-10 |
艾尼纳制药公司 |
治疗与s1p1受体有关的病症的方法
|
CN104529857B
(zh)
*
|
2015-01-13 |
2016-03-30 |
佛山市赛维斯医药科技有限公司 |
卤代金刚烷酰胺类衍生物、其制备方法和用途
|
MX2017009534A
(es)
|
2015-01-23 |
2018-04-10 |
Novartis Ag |
Conjugados de acidos grasos y apelina sintetica con mayor vida media.
|
CA2979033A1
(en)
|
2015-03-09 |
2016-09-15 |
Intekrin Therapeutics, Inc. |
Methods for the treatment of nonalcoholic fatty liver disease and/or lipodystrophy
|
CN104761456B
(zh)
*
|
2015-03-10 |
2020-04-10 |
上海威智医药科技有限公司 |
3-氨基-1-金刚烷醇的制备方法
|
CN104817482B
(zh)
*
|
2015-03-17 |
2017-05-10 |
宁波百思佳医药科技有限公司 |
2‑取代吡咯烷类化合物、制备方法及其在制备维格列汀中的应用
|
ES2929526T3
(es)
|
2015-06-22 |
2022-11-29 |
Arena Pharm Inc |
Sal cristalina de L-arginina del ácido (R)-2-(7-(4-ciclopentil-3-(trifluorometil)benciloxi)-1,2,3,4-tetrahidrociclo-penta[b]indol-3-il)acético para su uso en trastornos asociados al receptor S1P1
|
WO2017064635A2
(en)
|
2015-10-14 |
2017-04-20 |
Cadila Healthcare Limited |
Pyrrole compound, compositions and process for preparation thereof
|
RU2628573C2
(ru)
*
|
2015-11-27 |
2017-08-21 |
Общество с ограниченной ответственностью "Аллель Центр Инновационных Биотехнологий" |
Ингибитор дипептидилпептидазы-4 для лечения сахарного диабета 2-го типа
|
BR112018013195A2
(pt)
|
2015-12-28 |
2018-12-11 |
Wockhardt Ltd |
composição farmacêutica osmótica oral de vildagliptina
|
BR112018072401A2
(pt)
|
2016-06-10 |
2019-02-19 |
Boehringer Ingelheim International Gmbh |
combinações de linagliptina e metformina
|
DE102016116130A1
(de)
|
2016-08-30 |
2018-03-01 |
Universität Bielefeld |
Verfahren zur Herstellung chiraler Aminonitrile
|
WO2018050892A1
(en)
|
2016-09-16 |
2018-03-22 |
Galenicum Health S.L. |
Vildagliptin pharmaceutical compositions
|
JOP20190086A1
(ar)
|
2016-10-21 |
2019-04-18 |
Novartis Ag |
مشتقات نافثيريدينون جديدة واستخدامها في معالجة عدم انتظام ضربات القلب
|
US20180243263A1
(en)
|
2016-12-09 |
2018-08-30 |
Cadila Healthcare Ltd. |
Treatment for primary biliary cholangitis
|
WO2018162722A1
(en)
|
2017-03-09 |
2018-09-13 |
Deutsches Institut Für Ernährungsforschung Potsdam-Rehbrücke |
Dpp-4 inhibitors for use in treating bone fractures
|
CN110996951A
(zh)
|
2017-04-03 |
2020-04-10 |
科赫罗斯生物科学股份有限公司 |
治疗进行性核上性麻痹的PPARγ激动剂
|
GR1009406B
(el)
|
2017-10-03 |
2018-11-26 |
Φαρματεν Αβεε |
Φαρμακευτικο σκευασμα που περιλαμβανει βιλνταγλιπτινη και μεθοδος για την παρασκευη αυτου
|
UY38072A
(es)
|
2018-02-07 |
2019-10-01 |
Novartis Ag |
Compuestos derivados de éster butanoico sustituido con bisfenilo como inhibidores de nep, composiciones y combinaciones de los mismos
|
KR102622198B1
(ko)
|
2018-03-30 |
2024-01-09 |
한미약품 주식회사 |
빌다글립틴을 함유하는 경구용 고형제제 및 그의 제조 방법
|
GR1009644B
(el)
|
2018-09-25 |
2019-11-12 |
Φαρματεν Α.Β.Ε.Ε. |
Φαρμακευτικο σκευασμα που περιλαμβανει βιλνταγλιπτινη και μετφορμινη και μεθοδος για την παρασκευη αυτου
|
US20220024981A1
(en)
|
2018-11-27 |
2022-01-27 |
Novartis Ag |
Cyclic peptides as proprotein convertase subtilisin/kexin type 9 (pcsk9) inhibitors for the treatment of metabolic disorders
|
CN113166101A
(zh)
|
2018-11-27 |
2021-07-23 |
诺华股份有限公司 |
作为治疗代谢障碍的蛋白质原转换酶枯草杆菌蛋白酶/kexin 9型(PCSK9)抑制剂的环状五聚体化合物
|
UY38485A
(es)
|
2018-11-27 |
2020-06-30 |
Novartis Ag |
Compuestos tetrámeros cíclicos como inhibidores de proproteína convertasa subtilisina/kexina tipo 9 (pcsk9), método de tratamiento, uso y su preparación
|
JP7461735B2
(ja)
*
|
2019-12-02 |
2024-04-04 |
日本ジェネリック株式会社 |
ビルダグリプチン含有錠剤
|
CN113527167B
(zh)
*
|
2020-04-14 |
2024-01-19 |
威智医药股份有限公司 |
一种维格列汀的生产方法
|
WO2021234430A1
(en)
|
2020-05-17 |
2021-11-25 |
Lotus International Pte. Ltd. |
Modified release dosage form comprising vildagliptin and process for manufacturing the same
|
WO2022003405A1
(en)
|
2020-07-03 |
2022-01-06 |
Savoi Guilherme |
One-pot process to obtain a pyrrolidine-2-carbonitrile intermediate compound and industrial scale telescopic process to prepare (2s)-1-[n-(3-hydroxyadamantan-1-yl)glycyl]-2-pyrrolidinecarbonitrile (vildagliptin) using same
|
EP4192509A1
(de)
|
2020-08-05 |
2023-06-14 |
Ellipses Pharma Ltd |
Behandlung von krebs mit einem cyclodextrinhaltigen polymer-topoisomerase-inhibitor-konjugat und einem parp-inhibitor
|
CA3209219A1
(en)
*
|
2021-01-21 |
2022-07-28 |
The Scripps Research Institute |
Small molecule regulators of alveolar type 2 cell proliferation for the treatment of pulmonary diseases
|
TW202333563A
(zh)
|
2021-11-12 |
2023-09-01 |
瑞士商諾華公司 |
用於治療疾病或障礙之二胺基環戊基吡啶衍生物
|
AR127698A1
(es)
|
2021-11-23 |
2024-02-21 |
Novartis Ag |
Derivados de naftiridinona para el tratamiento de una enfermedad o un trastorno
|