The specific embodiment
Below, according to description of drawings embodiments of the invention 1 and embodiment 2.In addition, in the following description, the element with roughly the same function and structure is paid identical symbol, and only carry out repeat specification in the case of necessary.
(embodiment 1)
Fig. 1 represents the modular structure figure of the MR imaging apparatus 10 of present embodiment.The structure of this MR imaging apparatus 10 at first, is described with reference to Fig. 1.
This MR imaging apparatus 10 possess static field magnet 11, gradient magnetic field coil 13, whole body with high frequency (RF) coil 14, high frequency receiving coil 15, gradient magnetic field coil driving device 17, whole body with RF coil-driving apparatus of electronic 18, RF receiving-member 19, controller 20, accountant 21, display unit 23, input block 24, memory unit 25, be stored in ECG waveform collection device 31 in the ECG device 30, R ripple detection of stored device 32 constantly.
Static field magnet 11 is the Magnet that produces magnetostatic field, produces identical magnetostatic field.This static field magnet 11 is for example used permanent magnet, superconducting magnet etc., cools off by not shown cooling system.
Gradient magnetic field coil 13 is field coils of axial ratio static field magnet 11 weak points, is arranged on the inboard of static field magnet 11.Gradient magnetic field coil 13 forms the leaning magnetic field with linear tilt Distribution of Magnetic Field based on the pulse current of supplying with from gradient magnetic field coil driving device 17 on three directions of orthogonal X, Y, Z.By the leaning magnetic field that this gradient magnetic field coil 13 produces, determine signal generator position (position).
In addition, in the present embodiment, suppose that Z-direction is the direction (the axon direction of subject) identical with the magnetostatic field direction.In addition, in the present embodiment, gradient magnetic field coil 13 and static field magnet 11 have cylindrical shape.In addition, gradient magnetic field coil 13 also can dispose in a vacuum by the supporting structure of regulation.This be because: from the viewpoint of quietization, do not make since the vibration that applies the gradient magnetic field coil 13 that pulse current produces as sonic propagation to the outside.
Whole body is coils that camera watch region to subject applies the high-frequency impulse that is used to produce magnetic resonance signal with RF coil 14.For example under the situation of photography abdominal part etc., also use as receiving coil.
High frequency receiving coil (RF receiving coil) the 15th, the surface that can move (surface) coil that each position is had special-purpose shape.
Whole body has oscillating component, phase place alternative pack, frequency transform part, Modulation and Amplitude Modulation parts, high frequency filtration amplifier unit (all not having diagram) with RF coil-driving apparatus of electronic 18, and sends the high-frequency impulse corresponding with Larmor frequency to whole body with RF coil 14.The high frequency that produces with RF coil 14 from whole body owing to pass through this transmission, the nuclear magnetization of the regulation of subject becomes foment.
RF receiving-member 19 has amplifier unit, intermediate frequency transform component, phase detection parts, wave filter, A/D changer (all not having diagram), each magnetic resonance signal (high-frequency signal) that receives from each receptor is applied the signal processing of regulation respectively.That is, the magnetic resonance signal that discharged when foment relaxes for base state of 19 pairs of nuclear magnetization of receiving-member is implemented processing and amplifying, the intermediate frequency conversion process of having utilized transmission frequency, phase detection processing, Filtering Processing, A/D conversion process.
Controller 20 has not shown CPU, memorizer etc., and is as all control maincenters of system, static or dynamically control this MR imaging apparatus.Under the situation of (parallel) imaging that walks abreast, a plurality of RF receiving coils that controller 20 usefulness sensitivity profile are different are used to receive, handle the control of magnetic resonance signal concurrently especially.
In addition, controller 20 is according to the control sequence of regulation, and control gradient magnetic field coil driving device 17, whole body make to produce the pulse train that is used for memory photography described later with RF coil-driving apparatus of electronic 18.
21 pairs of accountants are collected by the digital signals of RF receiving-member 19 samplings, carry out the post processings such as reconstruct of Fourier transform etc., obtain the frequency spectrum data or the view data of the nuclear spin of tested intravital hope.In addition, accountant 21 is carried out the image generation of parallel imaging.At this, parallel imaging is meant following technology: use the different a plurality of RF receiving coils of sensitivity profile, the sequence that execution has been got between phase code has been carried out is returned and is removed de-artifact by matrix calculus and launch to handle, thereby shortens photography time.Under the situation of having carried out parallel imaging, respectively image is reconstructed according to magnetic resonance signal from each coil, use the sensitivity profile of each coil then, as the post processing of resulting many images, launch to handle, generate an image.
Display unit 23 is the output devices that show from the frequency spectrum data of accountant 22 input or view data etc. via controller 20.In addition, display unit 23 also can make topography relevant with the diagnosis position that is collected by miniature coils 15a and the wide area image of being collected by wide area coil 15b its mutual alignment relation synthesize (overlapping) accordingly or line up and side by side show.
Input block 24 is in order to obtain various indications from the operator, instruction, information and have input equipment (mouse, tracking ball, mode selector switch, keyboard etc.).
Magnetic resonance image data after magnetic resonance signal data before the reconstruct that memory unit 25 obtains via receiving-member 19 at each patient storage, the reconstruct that obtains via accountant 21 etc.
The ECG waveform that the time of the electrical phenomena of the heart of 31 pairs of expressions of ECG waveform collection device subject P changes is collected.
Detection of stored device 32 detections constantly of R ripple are produced constantly and are stored by the R ripple of each ECG waveform that ECG waveform collection device 31 is collected.
In addition, ECG waveform collection device 31 and R ripple detection of stored device 32 constantly all are arranged in the ECG device 30, but its structure has more than and be limited to this, for example also can be with the R ripple constantly detection of stored device 32 be arranged on the structure of the main body side of MR imaging apparatus 10.
(memory camera function)
Then, the memory camera function that this MR imaging apparatus 10 is had is described.This function can be divided into the function and the function in post processing (particularly image reconstruction) stage of sweep phase.At first, in sweep phase, the special time phase place (being the R ripple generation time phase place in the ECG waveform) of a heart beating as triggering, is carried out repeatedly scanning according to identical coding mode under present situation.In post-processing stages, to carry out the identical special time phase place of a heart beating that produces after the scanning as benchmark, begin from here to recall, use the necessary data of image reconstruction (for example data of an image) in the data that obtain by above-mentioned scanning to carry out image reconstruction.
Fig. 2 is the figure that is used to illustrate the memory camera function that MR imaging apparatus had of present embodiment, is that R ripple in the expression ECG waveform produces constantly and the figure of the periodic relation of scanning.The oblique line that the zero hour in each scan period and the finish time are coupled together among the figure is symbolically expressed the scanning consistent with the coding mode of stipulating.In addition, this oblique line rises interimly and (for example scans B
1, scanning B
2Oblique line compare scan A
1, scan A
2A high stage of oblique line) express the coding mode step-length of having advanced.
At this, scanning is meant a series of action till the leaning magnetic field that is used to select the leaning magnetic field of specific fault plane (section) to apply, carries out according to specific phase place and frequency coding pattern applies, applies by these magnetic fields the reception of the magnetic resonance signal of reading.
As shown in Figure 2, at first, will be at moment T
0The R ripple that produces is as triggering, from this T constantly
0Certain ECG of beginning implements scan A after time delay
1Follow this scan A
1Afterwards, circulate at least once and carry out and this A
1The scanning of identical coding mode, and collect data.In addition, in the example of Fig. 2, for the purpose of simplifying the description, represented that circulation carries out once and A
1Scanning (the scan A of identical coding mode
2) example.
Then, will be at moment T
0The next R ripple of the R ripple that produces is (that is, at moment T
1The R ripple that produces) as triggering, after certain time delay, carries out scanning B
1With with this scanning B
1The scanning B of identical coding mode
2This scans B
1With scanning B
2Be from scan A with coding mode
1And A
2The scanning of the regulation step-length of having advanced.
Make a video recording till necessary whole 3 dimension data to collect coronary artery by number of times that all circulations are put rules into practice, carry out these scanning sequences.The MR data that obtain like this and pairing each R ripple and data collection time information are stored in the memory unit 25 explicitly at any time.In addition, must not be associated, for example can constitute according to the TR in this scanning, TE, sampling time, afterwards calculating data collection time information yet with the data collection time information in this moment.
Then, based on the moment of data collection time information and R ripple, the phase of adjustment of clipping between T
AjProduce from next R ripple and to begin the time of carrying out constantly and recall as the R ripple that triggers, from the MR data of collecting, cut the picture needed data number of reconstruct (the data number of an image) of publishing picture, generation be used for to produce the data set that relevant heart movement is photographed as the expansion latter stage behind the R ripple that triggers, carry out image reconstruction.
That is, for example to will be at moment T
0The R ripple that produces is as triggering collected scan-data (with scan A
1And A
2Corresponding data), detect the moment T of next R ripple
1The coding step-length.In Fig. 2, in scan A
2Data ways in, produced next R ripple (T constantly
1The R ripple).Therefore, T between the phase of adjustment of at first clipping
AjGround is from this moment T
1Beginning the time of carrying out recalls, and cuts and is fetched into scan A
2Initial coding mode till data.
But, can not obtain the data of complete coding mode like this.Therefore, as shown in Figure 2, from scan A
1In cut out the data suitable with insufficient coding mode.In addition, under the scan condition of carrying out the same coding mode more than 3 times or 3 times, the data suitable with insufficient coding mode also can be and scan corresponding data arbitrarily.But,, it is desirable to use and try one's best and moment T from reducing because of the moving viewpoint that waits the pseudomorphism that produces of patient's body
1Approaching data.
Then, according to the scan A that cuts out
1Corresponding data and scan A
2Corresponding data generate the data set corresponding with complete coding mode.That is, to cut out and scan A
1Corresponding data and and scan A
2Corresponding data sort and make coding mode continuous, and become one group data set (in the example of Fig. 2, with from scan A
1To scan A
2Order sort, generate data set).
To produce cutting and sorting of the data constantly recalled as the next R ripple of the R ripple that triggers with such, be applicable to the data corresponding (scanning B with next R ripple as benchmark
1, scanning B
2) and successive thereafter and whole corresponding data of coding of step-lengths, generate and be used for total data group that the heart movement relevant with the expansion latter stage behind the R ripple that produces regulation photographed.
In addition, among Fig. 2 the phase of adjustment between T
AjCan be set to be worth arbitrarily (time).For example, when cutting out the data necessary amount beginning to recall from next R ripple as the R ripple that triggers, under the situation that hope just in time strictly begins to carry out from the generation of next R ripple constantly, can be set to T by switch of being arranged on the regulation in the input block 24 etc. is operated
Aj=0.
All exist each patient under the discrete situation of painstaking effort flowable state, such to adjusting time T
AjPositive adjustment useful especially.Thus, can realize that the data that are more suitable in coronary artery is described cut.
In addition, in the present embodiment, as Fig. 2, shown in Figure 3, each scanning in the phase of adjustment between T
AjBe set to the same (certain value).But,, each scanning is adjusted energetically so for example also can constitute because the situation that the cycle because of heart beatings such as holding one's breath of when photography changes is also arranged.
(photography action)
Then, the photography action coronarius of having used above-mentioned memory camera function is described.
Fig. 4 is the respectively flow chart of the flow process of processing that expression this MR imaging apparatus 10 is implemented when carrying out the coronary artery photography.
At first, for the regulation zone that comprises heart, from RF receiving coil 15 receiving magnetic resonance signals on one side position with photography (pilot scan) (step S1) on one side.In accountant 21,, and implement to launch to handle respectively to being reconstructed with each magnetic resonance signal of obtaining of photography by this location, as positioning image with a pictorial display on display unit 23, store into simultaneously in the memory unit 25.
Then, with reference to the positioning image that show on one side grasp coronarius position as diagnosis object on one side, RF receiving coil 15 is adjusted on the suitable position position (step S2) of decision photography section.
Then, execution is to the scanning (step S3) of this photography section.At this moment, shown in Fig. 2 (or Fig. 3), like that, carry out the scanning that generation more than 2 times or 2 times and each R ripple is regularly carried out accordingly at least according to same coding mode.
Then, according to the moment of the R ripple of storing with performed pulse train in time relatedly, recall in time, from collected data, cut the necessary data number of picture reconstruct of publishing picture, arrange, generate the data that are equivalent to complete coding mode (step S4) corresponding with this R ripple.
Then, use resulting 3 dimension data groups, carries out image reconstruct (step S5) is with resulting MR pictorial display (step S6) on display unit 23.
According to above-described structure, can access following effect.
According to this MR imaging apparatus, to produce constantly as the ripple of R arbitrarily of the R ripple back of triggering as benchmark, recall from this moment, employing is gone up the data that up-to-date scanning obtains by the time, in addition for the insufficient data of these data, utilization generates 3 complete dimension data by the data that obtained by the new scanning of trying one's best on the time that the coding mode identical with this scanning obtains.Therefore, even patient's R-R interval variation also can be collected the data in expansion latter stage of heart phase place all the time, can stably obtain good coronary artery picture.
(embodiment 2)
Then, embodiments of the invention 2 are described.Present embodiment is not to adopt ECG to postpone as embodiment 1, but carries out successive scanning, carries out the photography based on above-mentioned memory function.
Fig. 5 is the figure that is used to illustrate the memory camera function of embodiment 2, is to express that the R ripple produces constantly and the figure of the periodic relation of scanning.
At first, obtain (owning) patient's the average R-R time, will than its calipers fix time during be set to base period.Then, in this base period, as shown in Figure 5, the scanning of identical coding mode is carried out in circulation continuously, and the line data of going forward side by side is collected.The MR data corresponding with each phase code pattern collected like this and corresponding each R ripple and data collection time information are stored in the memory unit 25 explicitly at any time.
Behind data collection, according to the generation moment of data collection time information and each R ripple, by the step identical with embodiment 1, to produce constantly as the ripple of R arbitrarily of the R ripple back of triggering as benchmark, carry out from this moment temporally recalling, from collected MR data, cutting the picture reconstruct necessary data number and arranging of publishing picture, generating thus and be used for data set that the heart movement relevant with the expansion latter stage after the R ripple of regulation produces photographed, and carrying out image reconstruction.
In addition, can with among Fig. 5 the phase of adjustment between T
AjBe set to be worth arbitrarily on (time) this point the same with embodiment 1.For example, by being set to T
Aj=0, can be as shown in Figure 6, just in time with the generation of next R ripple constantly as benchmark, begin from here to recall, cut out the necessary data of reconstruct.
(photography action)
Carry out the coronary artery photography of the device relevant by following steps: in the step S3 of Fig. 3, carry out the successive scanning of not adopting ECG to postpone, in step S4, use above-mentioned memory function to carry out data and cut, arrange with present embodiment.
According to aforesaid structure, can access the effect the same with embodiment 1.In addition, owing to do not interrupt the RF pulse,, can further improve the ability of describing coronarius so kept the steady statue of spin sequence.
In addition, the present invention has more than and is limited to the foregoing description, the implementation phase, in the scope that does not break away from its aim, can be out of shape and specialize element.In addition, by a plurality of elements that the foregoing description disclosed are carried out appropriate combination, can form various inventions.Specifically, following such distortion example is for example arranged.
(1) in the above-described embodiments, from data set before, cut out insufficient data.Relative therewith, under the scan condition of carrying out the same phase code more than 3 times or 3 times, also can from the data set of the same coding mode before, cut, or interpolation and obtaining.For example, at interval short terrifically at R-R, begin to recall from the R ripple and can not get under the situation such as data necessary number, also can constitute and from the data of nearest same coding mode, cut and use, perhaps carry out interpolation and use from adjacent data.
(2) in the above-described embodiments, will produce the moment as benchmark, carry out cutting of the necessary data of reconstruct as the R ripple after the R ripple that triggers.This is " scanning triggers reconstruction datum constantly " to be set to " R-R " at interval, the same time phase that the benchmark that the data in the reconstruct are cut is set to trigger heart beating afterwards constantly.
But, must " scanning trigger reconstruction datum constantly " not be set to " R-R " at interval, for example also can constitute with " scanning triggers reconstruction datum constantly " be set to " 2R-R " (data in the reconstruct are cut benchmark to be set to constantly from triggering the same time phase every one heart beating), " 3R-R " (data the reconstruct are cut benchmark to be set to constantly from the same time phase of the heart beating that triggers next but two), with and above interval.
(3) in the various embodiments described above, constitute the conduct information relevant and use the ECG waveform with heart beating, as triggering the benchmark moment and the benchmark moment that is used for post processing, utilize the R ripple to produce constantly.But, have more than as the information relevant and to be limited to the ECG waveform with heart beating, if can grasp the information of each heart movement (being heart beating) constantly, then information can arbitrarily.As other object lessons, the image that can enumerate pulse wave, blood flow information, obtain by other devices (for example diagnostic ultrasound equipment), the MR signal that obtains by this MR imaging apparatus.
Especially under the situation of utilizing the MR signal that obtains by MR imaging apparatus, also can be by applying the pulse train that constitutes by high frequency magnetic field and leaning magnetic field continuously, carrying out 0 coded data continuously collects, with these data or to its variation of having carried out the data behind the one dimensional fourier transform as triggering, carry out imaging with scanning.That is, also can constitute by this MR imaging apparatus and obtain the MR signal that produces because of heart movement continuously, and carry out above-mentioned memory function according to it.
(4) in the foregoing description 2, with specific heart time phase (for example R ripple generation time phase place in the ECG waveform) of a heart beating as triggering, begin to scan.But, must not be set to specific heart time phase of a heart beating, also can constitute with scanning begin be set to arbitrarily constantly.
In addition, also can from the whole elements shown in each embodiment, delete several elements.And then, also can carry out appropriate combination to the element among the different embodiment.