CN105213268A - A kind of moisturizing eye cream of microcapsule-type - Google Patents
A kind of moisturizing eye cream of microcapsule-type Download PDFInfo
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- CN105213268A CN105213268A CN201510721614.3A CN201510721614A CN105213268A CN 105213268 A CN105213268 A CN 105213268A CN 201510721614 A CN201510721614 A CN 201510721614A CN 105213268 A CN105213268 A CN 105213268A
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- ethanol extract
- microcapsule
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/11—Encapsulated compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/35—Ketones, e.g. benzophenone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/731—Cellulose; Quaternized cellulose derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/732—Starch; Amylose; Amylopectin; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/733—Alginic acid; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/925—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of animal origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/56—Compounds, absorbed onto or entrapped into a solid carrier, e.g. encapsulated perfumes, inclusion compounds, sustained release forms
Abstract
The invention discloses a kind of moisturizing eye cream of microcapsule-type, be a kind of microcapsule of nucleocapsid structure, cyst material comprises potassium alginate, sodium hydroxyethyl cellulose and hyaluronic acid; Core materials comprises mink oil, squalane, lecithin, Jojoba wax, glycerol, batilol, serine, Maninot esculenta crantz. porous-starch, bupleurumol extract, Semen Coicis ethanol extract, Radix Paeoniae Alba ethanol extract, Dendrobium nobile ethanol extract, coenzyme Q10 and surfactant.The present invention adopts Maninot esculenta crantz. porous-starch, lubricant component in core materials and active component are adsorbed, and then the moisturizing eye cream making microcapsule-type of the present invention in use, can make to be adsorbed on active component in Maninot esculenta crantz. porous-starch and oils and fats slowly evenly discharges, and can not discharge in a large number the short time and bring too much nutrition and oil content to skin, and then can not cause the generation of fat granule, and the present invention also has the feature of good penetrability.
Description
Technical field
The invention belongs to microcapsule technology field, be specifically related to a kind of moisturizing eye cream of microcapsule-type.
Background technology
Eye skin is the thinnest skin of human body, is again activity position the most frequently simultaneously, but also is pull the maximum place of skin number of times in making up, and is very easy to grow wrinkle.The FAQs of eye has following several: black eye, eye pouch, edema, microgroove, dry stricture of vagina, crows-feet, fat granule, eyes lack expression etc., and these eye problems, once occur, are easy to make people seem aged without god.Eye cream is one of skin type product, and it can moisten eye part skin, alleviates the generation of wrinkle, microgroove, effectively prevents the generation of black eye, eye pouch problem, totally plays the effect alleviating eye part skin aging.Based on above-mentioned effect of eye cream, the personage that more and more likes to be beautiful using eye cream as one of daily indispensable skin care item.
If but the eye cream used is improper, also can bring certain harmful effect to eye skin.As most higher containing lubricant component in existing eye cream, contained neutraceutical active ingredients discharges too fast and is not easily absorbed, these oils and fatss or nutritional labeling are deposited on eye part skin, be easy to the generation causing fat granule for a long time in the past, fat granule, once produce elimination in the very difficult short time, can not be despised on the impact that eye part skin causes; If but the eye cream using quality comparatively frivolous, the moist degree of eye cream can be made again to decline, do not reach good maintenance effect.Moreover; the active substance adopted in existing eye cream is most not through certain protection, and directly contacts with external environment, along with the prolongation of time; these active substances be easy to be oxidized by the external world, photodissociation and lose the activity that should possess, and then cause product failure.
Summary of the invention
For prior art above shortcomings, technical problem to be solved by this invention is: the moisturizing eye cream how providing a kind of microcapsule-type, neutraceutical active ingredients in this product evenly can be discharged in use and is easy to absorb, have nourish effective, can not cause that fat granule produces, active substance is not easily by feature that external environment is destroyed.
In order to solve the problems of the technologies described above, the present invention adopts following technical scheme: a kind of moisturizing eye cream of microcapsule-type, and be a kind of microcapsule of nucleocapsid structure, cyst material comprises potassium alginate, sodium hydroxyethyl cellulose and hyaluronic acid; Core materials comprises mink oil, squalane, lecithin, Jojoba wax, glycerol, batilol, serine, Maninot esculenta crantz. porous-starch, bupleurumol extract, Semen Coicis ethanol extract, Radix Paeoniae Alba ethanol extract, Dendrobium nobile ethanol extract, coenzyme Q10 and surfactant.
Compared to existing technology, the present invention has following beneficial effect:
1, the present invention adopts Maninot esculenta crantz. porous-starch, lubricant component in core materials and active component are adsorbed, and then the moisturizing eye cream making microcapsule-type of the present invention in use, can make to be adsorbed on active component in Maninot esculenta crantz. porous-starch and oils and fats slowly evenly discharges, and can not discharge in a large number the short time and bring too much nutrition and oil content to skin, and then the generation of fat granule can not be caused.
2, in order to strengthen the moisturizing eye cream permeability of microcapsule-type of the present invention, the present invention is special by a large amount of experimental studies, choose mink oil, squalane, Jojoba wax, batilol is as core materials, and the collaborative compatibility relationship that further study between a few person, final discovery is when using " 16 ~ 22 parts of mink oils, 6 ~ 14 parts of squalanes, 6 ~ 8 parts of Jojoba waxes and 6 ~ 10 parts of batilols " time, the moist degree of this product can either be ensured, again can not be too greasy, and what is more important is when this several material plays collaborative compatibility effect with this ratio, the permeability of this product can be strengthened, and then enable skin fully absorb nutritional labeling, import respond well.
3, the present invention adopts microcapsule technology, neutraceutical active ingredients embedding is got up, makes this product in use, can not the impact that in external environment, light, heat, oxygen etc. are too much be subject to, effectively ensure that the activity of active substance is not destroyed, the effect extending product keeps the phase.
4, the present invention adopts active skull cap components as nutrient, and this several natural materials is carried out composite, them are made farthest to play collaborative compatibility effect, the moisturizing eye cream giving microcapsule-type of the present invention with moisturizing, eliminate bubble eye, alleviate black-eyed associating effect, and Dendrobium nobile ethanol extract also has good antioxidation, effectively stop light, ultraviolet to the damage of skin.
5, cyst wall hydrogel material of the present invention brings certain water moisture feeling to this product, and hyaluronic interpolation further increases the performance of keeping humidity of product, make this product in use, it is easier that eye part skin is pushed open, only need massage gently with finger and get final product uniform application, use convenient, the overnutrition at this position will be made to cause fat granule because product is deposited in a certain position of eye part skin.
6, shape of product of the present invention is regular, cyst wall has uniform thickness, and has uniform intensity, can retain the perfect shape of microcapsule and not be destroyed, the problem that capsule-core is revealed can not be caused, can not be damaged during effectively ensureing product stock, transport, shelf life.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is described in further detail, in the present embodiment if no special instructions, raw materials used be commercially available.
Described bupleurumol extract, Semen Coicis ethanol extract, Radix Paeoniae Alba ethanol extract, Dendrobium nobile ethanol extract are after the ethanol water of employing 60% carries out alcohol extraction to Radix Bupleuri, Semen Coicis, the Radix Paeoniae Alba and Dendrobium nobile respectively, successively the extract that obtains of decompression recycling ethanol, lyophilization.
In following embodiment, the moisturizing eye cream of microcapsule-type is adopted and is prepared with the following method:
(1) take potassium alginate, sodium hydroxyethyl cellulose and hyaluronic acid, add deionized water Ultrasonic Heating at 60 ~ 75 DEG C and dissolve 3 ~ 5min, obtain capsule wall solution A; Wherein, the deionized water volume added is 45 ~ 50 times of potassium alginate, sodium hydroxyethyl cellulose and hyaluronic acid gross mass; Ultrasonic power is 350 ~ 400W;
(2) mink oil, squalane, lecithin, Jojoba wax, glycerol, batilol, serine, Maninot esculenta crantz. porous-starch, bupleurumol extract, Semen Coicis ethanol extract, Radix Paeoniae Alba ethanol extract, Dendrobium nobile ethanol extract, coenzyme Q10 and surfactant mix homogeneously is taken, under 60 ~ 80 DEG C of water bath condition, stir 0.5 ~ 1h, obtain capsule-core mixture B; The mixing speed of wherein said stirring is 200 ~ 250r/min;
(3) mixed by capsule wall solution A and capsule-core mixture B, after blender dispersion 15 ~ 20min, homogenizing 3 ~ 8min, obtains homogenizing fluid C; Wherein, the rotating speed of described blender is 250 ~ 320r/min, and the homogenization pressure of described homogenizing is 40 ~ 50MPa;
(4) homogenizing fluid C is heated to 80 ~ 85 DEG C, using glue head dropper homogenizing fluid C to be slowly added dropwise to mass concentration is in the calcium chloride solution of 3% ~ 6%;
(5) calcium chloride solution after step (4) instillation homogenizing fluid C is filtered, discard filtrate, collect oversize;
(6) the oversize deionized water wash collected step (5) 2 ~ 3 times, obtains the moisturizing eye cream of described microcapsule-type.
Embodiment 1:
A moisturizing eye cream for microcapsule-type, be a kind of microcapsule of nucleocapsid structure, cyst material is: 55 parts of potassium alginates, 12 parts of sodium hydroxyethyl cellulose and 4 parts of hyaluronic acids; Core materials is: 16 parts of mink oils, 6 parts of squalanes, 4 parts of lecithin, 6 parts of Jojoba waxes, 10 parts of glycerol, 6 parts of batilols, 2 parts of serines, 8 parts of Maninot esculenta crantz. porous-starchs, 2 parts of bupleurumol extracts, 3 parts of Semen Coicis ethanol extract, 2 parts of Radix Paeoniae Alba ethanol extract, 1.5 parts of Dendrobium nobile ethanol extract, 1 part of coenzyme Q10 and 3 parts of polysorbate60s.
Embodiment 2:
A moisturizing eye cream for microcapsule-type, be a kind of microcapsule of nucleocapsid structure, cyst material is: 60 parts of potassium alginates, 18 parts of sodium hydroxyethyl cellulose and 8 parts of hyaluronic acids; Core materials is: 22 parts of mink oils, 14 parts of squalanes, 8 parts of lecithin, 8 parts of Jojoba waxes, 12 parts of glycerol, 10 parts of batilols, 4 parts of serines, 10 parts of Maninot esculenta crantz. porous-starchs, 4 parts of bupleurumol extracts, 4 parts of Semen Coicis ethanol extract, 3 parts of Radix Paeoniae Alba ethanol extract, 2 parts of Dendrobium nobile ethanol extract, 4 parts of coenzyme Q10s and 8 parts of polysorbate60s.
Embodiment 3:
A moisturizing eye cream for microcapsule-type, be a kind of microcapsule of nucleocapsid structure, cyst material is: 58 parts of potassium alginates, 16 parts of sodium hydroxyethyl cellulose and 6 parts of hyaluronic acids; Core materials is: 20 parts of mink oils, 10 parts of squalanes, 6 parts of lecithin, 8 parts of Jojoba waxes, 12 parts of glycerol, 8 parts of batilols, 4 parts of serines, 10 parts of Maninot esculenta crantz. porous-starchs, 4 parts of bupleurumol extracts, 4 parts of Semen Coicis ethanol extract, 2 parts of Radix Paeoniae Alba ethanol extract, 1.5 parts of Dendrobium nobile ethanol extract, 3 parts of coenzyme Q10s and 6 parts of polysorbate60s.
The present invention adopts Maninot esculenta crantz. porous-starch, lubricant component in core materials and active component are adsorbed, and then the moisturizing eye cream making microcapsule-type of the present invention in use, can make to be adsorbed on active component in Maninot esculenta crantz. porous-starch and oils and fats slowly evenly discharges, and can not discharge in a large number the short time and bring too much nutrition and oil content to skin, and then the generation of fat granule can not be caused.
In order to strengthen the moisturizing eye cream permeability of microcapsule-type of the present invention, the present invention is special by a large amount of experimental studies, choose mink oil, squalane, Jojoba wax, batilol is as core materials, and the collaborative compatibility relationship that further study between three, final discovery is when using " 16 ~ 22 parts of mink oils, 6 ~ 14 parts of squalanes, 6 ~ 8 parts of Jojoba waxes and 6 ~ 10 parts of batilols " time, the moist degree of this product can either be ensured, again can not be too greasy, and what is more important is when this several material plays collaborative compatibility effect with this ratio, the permeability of this product can be strengthened, and then enable skin fully absorb nutritional labeling, import respond well.
What finally illustrate is, above embodiment is only in order to illustrate technical scheme of the present invention and unrestricted, although applicant's reference preferred embodiment is to invention has been detailed description, those of ordinary skill in the art is to be understood that, technical scheme of the present invention is modified or equivalent replacement, and do not depart from the aim of technical solution of the present invention and scope, all should be encompassed in the middle of right of the present invention.
Claims (4)
1. a moisturizing eye cream for microcapsule-type, be a kind of microcapsule of nucleocapsid structure, it is characterized in that, cyst material comprises potassium alginate, sodium hydroxyethyl cellulose and hyaluronic acid; Core materials comprises mink oil, squalane, lecithin, Jojoba wax, glycerol, batilol, serine, Maninot esculenta crantz. porous-starch, bupleurumol extract, Semen Coicis ethanol extract, Radix Paeoniae Alba ethanol extract, Dendrobium nobile ethanol extract, coenzyme Q10 and surfactant.
2. the moisturizing eye cream of microcapsule-type according to claim 1, it is characterized in that, described surfactant is polysorbate60.
3. the moisturizing eye cream of microcapsule-type according to claim 2, it is characterized in that, the parts by weight of described cyst material are: 55 ~ 60 parts of potassium alginates, 12 ~ 18 parts of sodium hydroxyethyl cellulose and 4 ~ 8 parts of hyaluronic acids; The parts by weight of described core materials are: 16 ~ 22 parts of mink oils, 6 ~ 14 parts of squalanes, 4 ~ 8 parts of lecithin, 6 ~ 8 parts of Jojoba waxes, 10 ~ 12 parts of glycerol, 6 ~ 10 parts of batilols, 2 ~ 4 parts of serines, 8 ~ 10 parts of Maninot esculenta crantz. porous-starchs, 2 ~ 4 parts of bupleurumol extracts, 3 ~ 4 parts of Semen Coicis ethanol extract, 2 ~ 3 parts of Radix Paeoniae Alba ethanol extract, 1.5 ~ 2 parts of Dendrobium nobile ethanol extract, 1 ~ 4 part of coenzyme Q10 and 3 ~ 8 parts of polysorbate60s.
4. the moisturizing eye cream of microcapsule-type according to claim 2, it is characterized in that, the parts by weight of described cyst material are: 58 parts of potassium alginates, 16 parts of sodium hydroxyethyl cellulose and 6 parts of hyaluronic acids; The parts by weight of described core materials are: 20 parts of mink oils, 10 parts of squalanes, 6 parts of lecithin, 8 parts of Jojoba waxes, 12 parts of glycerol, 8 parts of batilols, 4 parts of serines, 10 parts of Maninot esculenta crantz. porous-starchs, 4 parts of bupleurumol extracts, 4 parts of Semen Coicis ethanol extract, 2 parts of Radix Paeoniae Alba ethanol extract, 1.5 parts of Dendrobium nobile ethanol extract, 3 parts of coenzyme Q10s and 6 parts of polysorbate60s.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510721614.3A CN105213268A (en) | 2015-10-30 | 2015-10-30 | A kind of moisturizing eye cream of microcapsule-type |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510721614.3A CN105213268A (en) | 2015-10-30 | 2015-10-30 | A kind of moisturizing eye cream of microcapsule-type |
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| CN105213268A true CN105213268A (en) | 2016-01-06 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2620608A (en) * | 2022-07-13 | 2024-01-17 | Landa Labs 2012 Ltd | Compositions comprising surface modified globular nano-particles |
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| US6391288B1 (en) * | 1999-07-27 | 2002-05-21 | Shiseido Co., Ltd. | Microcapsule and method of making the same |
| CN103202469A (en) * | 2013-03-28 | 2013-07-17 | 吉林大学 | Egg yolk lecithin microcapsules and preparation method thereof |
| CN104398392A (en) * | 2014-12-01 | 2015-03-11 | 重庆小丸科贸有限公司 | Hydrogel microcapsule and application thereof in anti-ageing cosmetic |
-
2015
- 2015-10-30 CN CN201510721614.3A patent/CN105213268A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6391288B1 (en) * | 1999-07-27 | 2002-05-21 | Shiseido Co., Ltd. | Microcapsule and method of making the same |
| CN103202469A (en) * | 2013-03-28 | 2013-07-17 | 吉林大学 | Egg yolk lecithin microcapsules and preparation method thereof |
| CN104398392A (en) * | 2014-12-01 | 2015-03-11 | 重庆小丸科贸有限公司 | Hydrogel microcapsule and application thereof in anti-ageing cosmetic |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2620608A (en) * | 2022-07-13 | 2024-01-17 | Landa Labs 2012 Ltd | Compositions comprising surface modified globular nano-particles |
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Application publication date: 20160106 |