CN103941032A - Automatic detector for biological samples - Google Patents
Automatic detector for biological samples Download PDFInfo
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- CN103941032A CN103941032A CN201410189692.9A CN201410189692A CN103941032A CN 103941032 A CN103941032 A CN 103941032A CN 201410189692 A CN201410189692 A CN 201410189692A CN 103941032 A CN103941032 A CN 103941032A
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- 239000012472 biological sample Substances 0.000 title claims abstract description 43
- 239000000523 sample Substances 0.000 claims abstract description 266
- 238000001514 detection method Methods 0.000 claims abstract description 241
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 187
- 238000004140 cleaning Methods 0.000 claims description 32
- 239000000376 reactant Substances 0.000 claims description 10
- 238000000034 method Methods 0.000 description 5
- 238000006243 chemical reaction Methods 0.000 description 4
- 239000003795 chemical substances by application Substances 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 230000005484 gravity Effects 0.000 description 2
- 210000002381 plasma Anatomy 0.000 description 2
- 239000000306 component Substances 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000004904 shortening Methods 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
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Abstract
The invention provides an automatic detector for biological samples. The automatic detector for the biological samples comprises a device base plate, a detection assembly with a testing cup, a sample adding needle, a reagent adding needle, and a detection assembly slide rail, wherein the sample adding needle can be used for sucking a sample and adding the sample into the testing cup and can move in X, Y and Z directions; the reagent adding needle can be used for sucking a reagent and adding the reagent into the testing cup and can move in the X, Y and Z directions; the detection assembly can be arranged on the detection assembly slide rail in a sliding manner and can move close to a sample area and a reagent area along the detection assembly slide rail. According to the automatic detector for the biologic samples, the detection assembly can carry out reciprocating motion along the detection assembly slide rail; the detection assembly can move towards the sample adding needle when the sample is added; the detection assembly can move towards the reagent adding needle when the reagent is added; therefore, the motion distance of the sample adding needle is shortened, the sample adding time and reagent adding time are shortened, the detection speed is improved, and the detection efficiency is improved.
Description
Technical field
The present invention relates to medical science and biological sample detection technique field, more particularly, relate to a kind of biological sample automatic detecting instrument.
Background technology
Along with the variation of society and environment, more and more health awareness problem of people on the one hand, on the other hand due to environmental change, the incidence of disease of disease is more and more higher, and the factor of this two aspect makes health check-up and the number of seeking medical advice significantly improves, and causes clinical detection quantity to increase.In order to meet the needs of clinical detection, medical personnel mainly detect samples such as full component blood or blood plasma by automatic detecting instrument, have saved human input.
At present, the sample pipetting volume pin that automatic detecting instrument has can be along X to, Y-direction, Z-direction moves and can be along X to, Y-direction, the reagent sample needle that moves of Z-direction, wherein, Z-direction is gravity direction, X is vertical between two with Z-direction to, Y-direction.When work, first make sample pipetting volume pin move to sample area along X to, Y-direction, then move and draw after sample along Z-direction, then move to detection components top sample is added in the test cup in detection components along X to, Y-direction; Then make reagent sample needle move to reagent area along X to, Y-direction, move and draw after reagent along Z-direction, move to again detection components top along X to, Y-direction reagent is added in the test cup in detection components, finally obtain the reaction result of the reactant of sample and reagent place generation in test cup by the photoeletric measuring system in detection components.
But, in the process of above-mentioned automatic detecting instrument work, only rely on two sample needles to move, when each application of sample or reagent adding, must move to detection components top by sample needle self and just can complete application of sample, mobile is distant, cause the time of application of sample and reagent adding longer, affected detection speed.
In sum, how shortening application of sample time and reagent adding time, to improve detection speed, and then improve detection efficiency, is current those skilled in the art technical matterss urgently to be resolved hurrily.
Summary of the invention
In view of this, the object of the present invention is to provide a kind of biological sample automatic detecting instrument, to shorten application of sample time and reagent adding time, improve detection speed, and then improve detection efficiency.
In order to achieve the above object, the invention provides following technical scheme:
A kind of biological sample automatic detecting instrument, comprising:
Instrument base plate, has sample area for placing sample tube and for placing the reagent area of reagent bottle on described instrument base plate;
There is the detection components of test cup;
Can draw sample and sample is added in described test cup, and can be along X to, Y-direction, the sample pipetting volume pin that moves of Z-direction;
Can draw reagent and reagent is added in described test cup, and can be along X to, Y-direction, the reagent sample needle that moves of Z-direction;
Also comprise:
Detection components slide rail, described detection components is slidably disposed on described detection components slide rail, and described detection components can be to moving near the direction of described sample area and described reagent area along described detection components slide rail.
Preferably, above-mentioned biological sample automatic detecting instrument also comprises the actuator that can drive described detection components to move to the direction of close described sample area and described reagent area along described detection components slide rail, and described actuator is connected with described detection components.
Preferably, above-mentioned biological sample automatic detecting instrument also comprises for controlling described actuator and moves to control described detection components along described detection components slide rail to the controller moving near the direction of described sample area and described reagent area, and described controller is connected with described actuator.
Preferably, in above-mentioned biological sample automatic detecting instrument, described actuator is motor.
Preferably, above-mentioned biological sample automatic detecting instrument also comprises:
All, along X to the first slide rail and the second slide rail that arrange, described the first slide rail and the second slide rail are all arranged on described instrument base plate;
The sample pipetting volume arm arranging along Y-direction, one end of described sample pipetting volume arm is slidably disposed on described the first slide rail, and the other end of described sample pipetting volume arm is slidably disposed on described the second slide rail;
The reagent sample arm arranging along Y-direction, one end of described reagent sample arm is slidably disposed on described the first slide rail, and the other end of described reagent sample arm is slidably disposed on described the second slide rail;
Can be arranged on movably the sample pin guide holder on described sample pipetting volume arm along Y-direction, described sample pipetting volume pin can be arranged on described sample pin guide holder movably along Z-direction;
Can be arranged on movably the reagent needles guide holder on described reagent sample arm along Y-direction, described reagent sample needle can be arranged on described reagent needles guide holder movably along Z-direction.
Preferably, in above-mentioned biological sample automatic detecting instrument, described sample area and described reagent area are along X to being distributed on described instrument base plate, described sample area has many rows along X to the sample spacing hole of arranging, the described sample spacing hole of every row has multiple described sample spacing holes, described reagent area has many rows along X to the reagent spacing hole of arranging, the described reagent spacing hole of every row has multiple described reagent spacing holes; And described test cup is multiple.
Preferably, above-mentioned biological sample automatic detecting instrument also comprises the cleaning device that has completed the reactant after detection in described detection components for cleaning, described cleaning device is arranged on described instrument base plate and is positioned at the top of described detection components slide rail, and described detection components along described detection components slide rail can move to described cleaning device under.
Preferably, in above-mentioned biological sample automatic detecting instrument, described cleaning device is positioned at the side of described reagent area away from described sample area;
Described detection components slide rail is along X to arranging and extending to described cleaning device one end away from described reagent area by described sample area away from one end of described reagent area; Described in the time that described sample pipetting volume pin moves to described sample area, detection components can be along described detection components slide rail synchronizing moving under described sample pipetting volume arm, in the time that described reagent sample needle moves to described reagent area described in detection components can be along described detection components slide rail synchronizing moving to described reagent sample arm under.
Preferably, in above-mentioned biological sample automatic detecting instrument, described detection components slide rail comprises the first detection components slide rail, the second detection components slide rail and the 3rd detection components slide rail;
Described detection components comprises the first detection components, the second detection components and the 3rd detection components, described the first detection components is slidably disposed on described the first detection components slide rail, described the second detection components is slidably disposed on described the second detection components slide rail, and described the 3rd detection components is slidably disposed on described the 3rd detection components slide rail; And described sample pipetting volume pin can add sample to described the first detection components, described the second detection components and described the 3rd detection components successively, described reagent sample needle can carry out reagent adding to described the first detection components, described the second detection components and described the 3rd detection components successively, and described cleaning device can clean described the first detection components, described the second detection components and described the 3rd detection components successively.
Preferably, in above-mentioned biological sample automatic detecting instrument, described sample pipetting volume pin, described reagent sample needle, described sample pipetting volume arm and described reagent sample arm are multiple, and described sample pipetting volume pin is arranged on described sample pipetting volume arm correspondingly, and described reagent sample needle is arranged on described reagent sample arm correspondingly.
Can find out from above-mentioned technical scheme, biological sample automatic detecting instrument provided by the invention comprises instrument base plate, detection components, sample pipetting volume pin, reagent sample needle and detection components slide rail; Wherein, on instrument base plate, there is sample area for placing sample tube and for placing the reagent area of reagent bottle; Detection components has test cup; Sample pipetting volume pin can be drawn sample and sample is added in test cup, and can be along X to, Y-direction, Z-direction moves; Reagent sample needle can be drawn reagent and reagent is added in test cup, and can be along X to, Y-direction, Z-direction moves; Detection components is slidably disposed on detection components slide rail, and detection components can be to moving near the direction of sample area and reagent area along detection components slide rail.
When biological sample automatic detecting instrument work of the present invention, first make sample pipetting volume pin move to sample area, make detection components synchronously move to the direction near sample area along detection components slide rail simultaneously, after sample pipetting volume pin is drawn sample, then above moving to detection components, sample is added in the test cup in detection components; Then make reagent sample needle move to reagent area, make detection components synchronously move to the direction near reagent area along detection components slide rail simultaneously, candidate agent sample needle is drawn after reagent, then above moving to detection components, reagent is added in the test cup in detection components; Finally by the reaction result of the reactant that in the photoeletric measuring system acquisition test cup in detection components, sample and reagent place produce.
Detection components of the present invention can be along the to-and-fro movement of detection components slide rail, in the time need to adding sample, detection components can move to the direction near sample pipetting volume pin, in the time needing reagent adding, detection components can move to the direction near reagent sample needle, shorten the distance that sample needle self need to move, thereby application of sample time and reagent adding time are shortened, improve detection speed, and then improved detection efficiency.
Brief description of the drawings
In order to be illustrated more clearly in the embodiment of the present invention or technical scheme of the prior art, to the accompanying drawing of required use in embodiment or description of the Prior Art be briefly described below, apparently, accompanying drawing in the following describes is some embodiments of the present invention, for those of ordinary skill in the art, do not paying under the prerequisite of creative work, can also obtain according to these accompanying drawings other accompanying drawing.
Fig. 1 is the vertical view of the biological sample automatic detecting instrument that provides of the embodiment of the present invention;
Fig. 2 is the left view of the biological sample automatic detecting instrument that provides of the embodiment of the present invention.
Embodiment
The embodiment of the present invention provides a kind of biological sample automatic detecting instrument, has shortened application of sample time and reagent adding time, has improved detection speed, and then has improved detection efficiency.
For making object, technical scheme and the advantage of the embodiment of the present invention clearer, below in conjunction with the accompanying drawing in the embodiment of the present invention, technical scheme in the embodiment of the present invention is clearly and completely described, obviously, described embodiment is the present invention's part embodiment, instead of whole embodiment.Based on the embodiment in the present invention, those of ordinary skill in the art, not making the every other embodiment obtaining under creative work prerequisite, belong to the scope of protection of the invention.
Please refer to accompanying drawing, the biological sample automatic detecting instrument that the embodiment of the present invention provides comprises instrument base plate 14, detection components 2, sample pipetting volume pin 12, reagent sample needle 6 and detection components slide rail 5; Wherein, on instrument base plate 14, there is sample area 10 for placing sample tube and for placing the reagent area 9 of reagent bottle; Detection components 2 has test cup; Sample pipetting volume pin 12 can be drawn sample and sample is added in test cup, and can be along X to, Y-direction, Z-direction moves; Reagent sample needle 6 can be drawn reagent and reagent is added in test cup, and can be along X to, Y-direction, Z-direction moves; Detection components 2 is slidably disposed on detection components slide rail 5, and detection components 2 can be to moving near the direction of sample area 10 and reagent area 9 along detection components slide rail 5.
It should be noted that, above-mentioned Z-direction is gravity direction, and X is vertical between two with Z-direction to, Y-direction.Above-mentioned sample is medical science or biological sample, for example full composition blood, blood plasma, urine etc.
When biological sample automatic detecting instrument work of the present invention, first make sample pipetting volume pin 12 move to sample area 10, make detection components 2 synchronously move to the direction near sample area 10 along detection components slide rail 5 simultaneously, draw after sample until sample pipetting volume pin 12, then move to detection components 2 tops sample is added in the test cup in detection components 2; Then make reagent sample needle 6 move to reagent area 9, make detection components 2 synchronously move to the direction near reagent area 9 along detection components slide rail 5 simultaneously, candidate agent sample needle 6 is drawn after reagent, then moves to detection components 2 tops reagent is added in the test cup in detection components 2; Finally by the reaction result of the reactant that in the photoeletric measuring system acquisition test cup in detection components 2, sample and reagent place produce, concrete by measuring the change of photoelectric signal of the interior reactant of test cup, obtain reaction result by colorimetric or than turbid method.
Detection components 2 of the present invention can be along 5 to-and-fro movements of detection components slide rail, in the time need to adding sample, detection components 2 can move to the direction near sample pipetting volume pin 12, in the time needing reagent adding, detection components 2 can move to the direction near reagent sample needle 6, shorten the distance that sample needle self need to move, thereby application of sample time and reagent adding time are shortened, improve detection speed, and then improve detection efficiency, be specially adapted to the detection to batch samples, for example, be applied to large-scale MEC.
Preferably, biological sample automatic detecting instrument also comprises the actuator that can drive detection components 2 to move to the direction of close sample area 10 and reagent area 9 along detection components slide rail 5, and actuator is connected with detection components 2.The present invention drives detection components 2 along 5 to-and-fro movements of detection components slide rail by actuator, has saved manpower.Certainly, also can promote detection components 2 by external force slides.
Further, biological sample automatic detecting instrument also comprises for controlling actuator and moves to control detection components 2 along detection components slide rail 5 to the controller moving near the direction of sample area 10 and reagent area 9, and controller is connected with actuator.In the time that sample pipetting volume pin 12 moves to sample area 10, controller is automatically controlled actuator and is synchronously opened, and utilizes actuator to order about detection components 2 and moves to the direction near sample area 10 along detection components slide rail 5; In the time that reagent sample needle 6 moves to reagent area 9, controller is automatically controlled actuator and is synchronously opened, utilize actuator that detection components 2 is synchronously moved to the direction near reagent area 9 along detection components slide rail 5, realize the automated movement of detection components 2, improve robotization, further saved manpower.
Above-mentioned actuator is preferably motor, and running and comparing is steady, and control accuracy is higher.Interchangeable, actuator can also be cylinder and electric pushrod.
As shown in Figure 1, in the present invention's one specific embodiment, biological sample automatic detecting instrument comprises the first slide rail 1, the second slide rail 8, sample pipetting volume arm 13, reagent sample arm 3, sample pin guide holder 11 and reagent needles guide holder 7; Wherein, the first slide rail 1 and the second slide rail 8 are all along X to setting, and both are all arranged on instrument base plate 14; Sample pipetting volume arm 13 is along Y-direction setting, and its one end is slidably disposed on the first slide rail 1, and the other end is slidably disposed on the second slide rail 8; Reagent sample arm 3 is along Y-direction setting, and its one end is slidably disposed on the first slide rail 1, and the other end is slidably disposed on the second slide rail 8; Sample pin guide holder 11 can be arranged on sample pipetting volume arm 13 movably along Y-direction, and sample pipetting volume pin 12 can be arranged on sample pin guide holder 11 movably along Z-direction; Reagent needles guide holder 7 can be arranged on reagent sample arm 3 movably along Y-direction, and reagent sample needle 6 can be arranged on reagent needles guide holder 7 movably along Z-direction.
The present invention is moved and then drives sample pipetting volume pin 12 along X to movement along two slide rails by sample pipetting volume arm 13, is moved and then drives sample pipetting volume pin 12 to move along Y-direction along sample pipetting volume arm 13 by sample pin guide holder 11; Move and then drive reagent sample needle 6 along X to movement along two slide rails by reagent sample arm 3 simultaneously, move and then drive reagent sample needle 6 to move along Y-direction along reagent sample arm 3 by reagent needles guide holder 7; Make again sample pipetting volume pin 12 carry out Z-direction on sample pin guide holder 11 and move, reagent sample needle 6 carries out Z-direction and moves on reagent needles guide holder 7; Thereby realized sample pipetting volume pin 12 and reagent sample needle 6 at X to the movement in, Y-direction, Z-direction.Said structure is fairly simple, is convenient to the movement of sample pipetting volume pin 12 and reagent sample needle 6.
It will be understood by those skilled in the art that, said structure can also be other implementations, as sample pipetting volume pin 12 is fixed on sample pin guide holder 11, reagent sample needle 6 is fixed on reagent needles guide holder 7, and sample pipetting volume arm 13 and reagent sample arm 3 all can be moved along Z-direction, to reach the same effect that sample needle is moved to, Y-direction, Z-direction at X, introduce no longer one by one at this.
For the ease of drawing sample and reagent, sample area 10 and reagent area 9 are along X to being distributed on instrument base plate 14, and so, the movement of detection components 2 between sample area 10 and reagent area 9, in the close together of Y-direction, is convenient in sample area 10 and reagent area 9.Above-mentioned sample area 10 and reagent area 9 also can be distributed on instrument base plate 14 along Y-direction.
Further, sample area 10 has many rows along X to the sample spacing hole of arranging, every stock layout product spacing hole has multiple sample spacing holes, and reagent area 9 has many rows along X to the reagent spacing hole of arranging, every row's reagent spacing hole has multiple reagent spacing holes; And the test cup in detection components 2 is multiple.An above-mentioned sample spacing hole can be placed a sample tube, and a reagent spacing hole can be placed a reagent bottle, and so, multiple sample tubes can be placed in sample area 10 simultaneously, and multiple reagent bottles can be placed in reagent area 9.When work, this biological sample automatic detecting instrument can carry out the detection of multiple samples simultaneously, simultaneously because spacing hole is along X to movement, in the time drawing same row's sample or reagent, only needs corresponding sample arm along X to movement, shorten displacement, improved detection speed.
Biological sample automatic detecting instrument also comprises the cleaning device 4 that has completed the reactant after detection in detection components 2 for cleaning, cleaning device 4 is arranged on instrument base plate 14 and is positioned at the top of detection components slide rail 5, and detection components 2 along detection components slide rail 5 can move to cleaning device 4 under.After detection completes, by controller automatically control detection components 2 along detection components slide rail 5 move to cleaning device 4 under, thereby utilize cleaning device 4 automatically the reactant in detection components 2 to be cleaned up; And then can reuse test cup, save cost.
Cleaning device 4 is positioned at the side of reagent area 9 away from sample area 10; As shown in Figure 1, sample area 10 is positioned at 9 left sides, reagent area, and cleaning device 4 is positioned at 9 right sides, reagent area; So, cleaning device 4, away from sample area 10 and reagent area 9, can be avoided cleaning fluid to be splashed into sample area 10 and reagent area 9, and then avoid contaminated samples and reagent.
In the present embodiment, detection components slide rail 5 is along X to arranging and extending to cleaning device 4 one end (being the right-hand member in Fig. 1) away from reagent area 9 by sample area 10 away from one end (being the left end in Fig. 1) of reagent area 9; So, detection components 2 can move back and forth along detection components slide rail 5 between the left end of sample area 10 and the right-hand member of cleaning device 4.
Biological sample automatic detecting instrument is in the process of work, in the time that sample pipetting volume pin 12 moves to sample area 10, control detection components 2 along detection components slide rail 5 synchronizing movings under sample pipetting volume arm 13, draw after sample until sample pipetting volume pin 12, only make sample pipetting volume pin 12Y to moving or need to sample being added in the test cup in detection components 2 above mobile less distance is movable to detection components 2 at X; When reagent sample needle 6 is during to reagent area 9, control detection components 2 along detection components slide rail 5 synchronizing movings under reagent sample arm 3, candidate agent sample needle 6 is drawn after reagent, only makes reagent sample needle 6Y to moving or need to above mobile less distance is movable to detection components 2, reagent being added in the test cup in detection components 2 at X.
Because the present invention can make sample pipetting volume pin 12 and reagent sample needle 6 in the time carrying out application of sample, two sample arms on directions X, need hardly motion or move distance very little, greatly shorten the distance that two sample pins move to detection components 2 tops, therefore further saved detection time.
In the present invention's one preferred embodiment, detection components slide rail 5 comprises the first detection components slide rail, the second detection components slide rail and the 3rd detection components slide rail; Detection components 2 comprises the first detection components, the second detection components and the 3rd detection components, the first detection components is slidably disposed on the first detection components slide rail, the second detection components is slidably disposed on the second detection components slide rail, and the 3rd detection components is slidably disposed on the 3rd detection components slide rail; And sample pipetting volume pin 12 can add sample to the first detection components, the second detection components and the 3rd detection components successively, reagent sample needle 6 can carry out reagent adding to the first detection components, the second detection components and the 3rd detection components successively, and cleaning device 4 can clean the first detection components, the second detection components and the 3rd detection components successively.
In the present embodiment, detection components slide rail 5 is made up of three slide rails, is provided with a detection components 2 on each slide rail; This biological sample automatic detecting instrument is in the process of work, and by three detection components 2, moving back and forth on slide rail separately, makes detector can synchronously add respectively the operation of sample, reagent adding and cleaning test cup to three detection components 2; So, sample pipetting volume pin 12 can add sample to the detection components 2 after cleaning continuously, reagent sample needle 6 can be continuously to adding the detection components 2 of sample to add the related reagent of reagent area 9, and cleaning device 4 can clean up the reactant in the detection components 2 completing after detection continuously; Detection components 2 can be reused, and automatic cycle adds sample, reagent adding and cleaning operation.
In summary, sample pipetting volume pin 12 of the present invention, reagent sample needle 6 and cleaning device 4 can operate different detection components 2 simultaneously accordingly, make each detection components 2 in the time of work, mutually not at the same area, do not produce phase mutual interference, need to move to corresponding position by relevant separately, there is not the mutual conflict on the space of motion, save the time of mutual wait, can realize sample pipetting volume arm 13 and reagent sample arm 3 and carry out application of sample simultaneously; So, the reciprocating work in combination of three detection components 2 of utilizing the present embodiment can realize undelayed high speed and the continuous working of " adding sample → reagent adding detecting reactant result → test cup cleans ", make the present invention solve the slow problem of existing detecting instrument detection speed with the most efficient method of operation, be specially adapted to batch samples to carry out high speed detection processing.
Certainly, detection components 2 of the present invention can also be 1,2 or other numbers, and its quantity is selected according to the demand of detection speed.
In order to accelerate detection efficiency, in above-mentioned biological sample automatic detecting instrument, sample pipetting volume pin 12, reagent sample needle 6, sample pipetting volume arm 13 and reagent sample arm 3 are multiple, and sample pipetting volume pin 12 is arranged on sample pipetting volume arm 13 correspondingly, and reagent sample needle 6 is arranged on reagent sample arm 3 correspondingly.The present invention can make multiple sample pipetting volume pins 12 move to respectively different sample tube top, sample area 10, and utilizes sample pipetting volume pin 12 that sample is added in detection components 2 in multiple test cups; Make multiple reagent sample needles 6 move to respectively different reagent bottle top, reagent area 9 simultaneously, and utilize reagent sample needle 6 that related reagent is added and added in the test cup of sample accordingly; And then can utilize multiple test cups to test simultaneously, accelerate detection speed.
In this instructions, each embodiment adopts the mode of going forward one by one to describe, and what each embodiment stressed is and the difference of other embodiment, between each embodiment identical similar part mutually referring to.
To the above-mentioned explanation of the disclosed embodiments, make professional and technical personnel in the field can realize or use the present invention.To be apparent for those skilled in the art to the multiple amendment of these embodiment, General Principle as defined herein can, in the situation that not departing from the spirit or scope of the present invention, realize in other embodiments.Therefore, the present invention will can not be restricted to these embodiment shown in this article, but will meet the widest scope consistent with principle disclosed herein and features of novelty.
Claims (10)
1. a biological sample automatic detecting instrument, comprising:
Instrument base plate (14), has sample area (10) for placing sample tube and for placing the reagent area (9) of reagent bottle on described instrument base plate (14);
There is the detection components (2) of test cup;
Can draw sample and sample is added in described test cup, and can be along X to, Y-direction, the sample pipetting volume pin (12) that moves of Z-direction;
Can draw reagent and reagent is added in described test cup, and can be along X to, Y-direction, the reagent sample needle (6) that moves of Z-direction;
It is characterized in that, also comprise:
Detection components slide rail (5), it is upper that described detection components (2) is slidably disposed on described detection components slide rail (5), and described detection components (2) can be to moving near the direction of described sample area (10) and described reagent area (9) along described detection components slide rail (5).
2. biological sample automatic detecting instrument as claimed in claim 1, it is characterized in that, also comprise and can drive described detection components (2) along described detection components slide rail (5) to the actuator moving near the direction of described sample area (10) and described reagent area (9), described actuator is connected with described detection components (2).
3. biological sample automatic detecting instrument as claimed in claim 2, it is characterized in that, also comprise for controlling described actuator and move to control described detection components (2) along described detection components slide rail (5) to the controller moving near the direction of described sample area (10) and described reagent area (9), described controller is connected with described actuator.
4. biological sample automatic detecting instrument as claimed in claim 3, is characterized in that, described actuator is motor.
5. biological sample automatic detecting instrument as claimed in claim 3, is characterized in that, also comprises:
All, along X to the first slide rail (1) and the second slide rail (8) that arrange, described the first slide rail (1) and the second slide rail (8) are all arranged on described instrument base plate (14);
The sample pipetting volume arm (13) arranging along Y-direction, it is upper that one end of described sample pipetting volume arm (13) is slidably disposed on described the first slide rail (1), and the other end of described sample pipetting volume arm (13) is slidably disposed on described the second slide rail (8);
The reagent sample arm (3) arranging along Y-direction, it is upper that one end of described reagent sample arm (3) is slidably disposed on described the first slide rail (1), and the other end of described reagent sample arm (3) is slidably disposed on described the second slide rail (8);
Can be arranged on movably the sample pin guide holder (11) on described sample pipetting volume arm (13) along Y-direction, described sample pipetting volume pin (12) can be arranged on described sample pin guide holder (11) movably along Z-direction;
Can be arranged on movably the reagent needles guide holder (7) on described reagent sample arm (3) along Y-direction, described reagent sample needle (6) can be arranged on described reagent needles guide holder (7) movably along Z-direction.
6. biological sample automatic detecting instrument as claimed in claim 5, it is characterized in that, described sample area (10) and described reagent area (9) are along X to being distributed on described instrument base plate (14), described sample area (10) has many rows along X to the sample spacing hole of arranging, the described sample spacing hole of every row has multiple described sample spacing holes, described reagent area (9) has many rows along X to the reagent spacing hole of arranging, the described reagent spacing hole of every row has multiple described reagent spacing holes; And described test cup is multiple.
7. biological sample automatic detecting instrument as claimed in claim 6, it is characterized in that, also comprise the cleaning device (4) that has completed the reactant after detection in described detection components (2) for cleaning, described cleaning device (4) is arranged on described instrument base plate (14) goes up and is positioned at the top of described detection components slide rail (5), and described detection components (2) along described detection components slide rail (5) can move to described cleaning device (4) under.
8. biological sample automatic detecting instrument as claimed in claim 7, is characterized in that, described cleaning device (4) is positioned at the side of described reagent area (9) away from described sample area (10);
Described detection components slide rail (5) is along X to arranging and extending to described cleaning device (4) one end away from described reagent area (9) by described sample area (10) away from the one end of described reagent area (9); Described in the time that described sample pipetting volume pin (12) moves to described sample area (10), detection components (2) can be along described detection components slide rail (5) synchronizing moving under described sample pipetting volume arm (13), in the time that described reagent sample needle (6) moves to described reagent area (9) described in detection components (2) can be along described detection components slide rail (5) synchronizing moving to described reagent sample arm (3) under.
9. biological sample automatic detecting instrument as claimed in claim 7, is characterized in that, described detection components slide rail (5) comprises the first detection components slide rail, the second detection components slide rail and the 3rd detection components slide rail;
Described detection components (2) comprises the first detection components, the second detection components and the 3rd detection components, described the first detection components is slidably disposed on described the first detection components slide rail, described the second detection components is slidably disposed on described the second detection components slide rail, and described the 3rd detection components is slidably disposed on described the 3rd detection components slide rail; And described sample pipetting volume pin (12) can add sample to described the first detection components, described the second detection components and described the 3rd detection components successively, described reagent sample needle (6) can carry out reagent adding to described the first detection components, described the second detection components and described the 3rd detection components successively, and described cleaning device (4) can clean described the first detection components, described the second detection components and described the 3rd detection components successively.
10. the biological sample automatic detecting instrument as described in claim 5-9 any one, it is characterized in that, described sample pipetting volume pin (12), described reagent sample needle (6), described sample pipetting volume arm (13) and described reagent sample arm (3) are multiple, and it is upper that described sample pipetting volume pin (12) is arranged on described sample pipetting volume arm (13) correspondingly, and described reagent sample needle (6) is arranged on described reagent sample arm (3) correspondingly.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410189692.9A CN103941032B (en) | 2014-05-06 | 2014-05-06 | A kind of biological sample automatic detecting instrument |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410189692.9A CN103941032B (en) | 2014-05-06 | 2014-05-06 | A kind of biological sample automatic detecting instrument |
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| CN105675591A (en) * | 2016-01-05 | 2016-06-15 | 李作水 | Automatic chemiluminescence immunoassay apparatus |
| CN109060987A (en) * | 2018-08-28 | 2018-12-21 | 兰州大学 | Seed integrated treatment unit before dogstail kind band endogenetic fungus microscopy |
| CN112229979A (en) * | 2020-10-11 | 2021-01-15 | 中建路桥集团有限公司 | High-efficiency geotechnical test saturation cylinder using magnetic force |
| WO2021238109A1 (en) * | 2020-05-25 | 2021-12-02 | 北京中勤世帝生物技术有限公司 | Fixed-rate test method for blood coagulation routine test |
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| CN103941032B (en) | 2016-09-07 |
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Effective date of registration: 20170412 Address after: 215500 Jiangsu economic and Technological Development Zone, Changshou City hi tech Industrial Park, Jianye Road, No. 4, building 2 Patentee after: ZIRCON BIOTECH Co.,Ltd. Address before: 102200 Changping District science and Technology Park, Beijing, ultra Road, No. 4, No. 5 B302 Patentee before: BEIJING STEELLEX BIOLOGICAL TECHNOLOGY Co.,Ltd. |
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Denomination of invention: An automated detection instrument for biological samples Granted publication date: 20160907 Pledgee: Bank of Jiangsu Co.,Ltd. Suzhou Branch Pledgor: ZIRCON BIOTECH Co.,Ltd. Registration number: Y2024980011037 |