CN103585684A - Separate-type extracorporeal circulation system - Google Patents

Separate-type extracorporeal circulation system Download PDF

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Publication number
CN103585684A
CN103585684A CN201310617436.0A CN201310617436A CN103585684A CN 103585684 A CN103585684 A CN 103585684A CN 201310617436 A CN201310617436 A CN 201310617436A CN 103585684 A CN103585684 A CN 103585684A
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China
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extracorporeal circulation
computer system
blood
lower computer
pump
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CN201310617436.0A
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Chinese (zh)
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王洋
周晓明
苏友超
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University of Electronic Science and Technology of China
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University of Electronic Science and Technology of China
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Priority to CN201310617436.0A priority Critical patent/CN103585684A/en
Publication of CN103585684A publication Critical patent/CN103585684A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621Extra-corporeal blood circuits

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  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • External Artificial Organs (AREA)

Abstract

The invention discloses a separate-type extracorporeal circulation system which comprises an upper computer system, a lower computer system and an extracorporeal circulation device. The upper computer system can exist independently, the lower computer system and the extracorporeal circulation device can be integrated into a whole and can also exist mutually independently, the upper computer system is in wired or wireless data connection with the lower computer system, and the lower computer system is in wired or wireless data connection with the extracorporeal circulation device. Compared with a traditional extracorporeal circulation system, especially a hemodialysis machine, the separate-type extracorporeal circulation system enables the upper computer system to be independent, therefore, on one hand, the size of the extracorporeal circulation system is obviously reduced, the extracorporeal circulation system is made to be easy to carry, a patient can perform repeated short-time dialysis or night dialysis treatment at home, the medical care cost is reduced, and meanwhile the toxin tolerance of the dialysis patient during dialysis is reduced; on the other hand, the upper computer system can perform programming, networking and remote controlling conveniently, and therefore networking and intellectualization of the separate-type extracorporeal circulation system are achieved.

Description

Separate type extracorporeal circulation system
Technical field
The invention belongs to field of medical device, be specifically related to a kind of for realizing the separate type extracorporeal circulation system of blood purification.
Background technology
Extracorporeal circulation (extracorporeal circulation) is that to utilize a series of special Prosthesises that blood in body is drained into external, through manual method, carries out gas or composition exchange, regulates after temperature the life support technology in defeated the Huis' body again.According to the difference of external exchange composition, extracorporeal circulation system can be divided into the multiclass such as artificial kidney, artificial liver and artificial heart, has clinically application very widely.Take artificial kidney system as example, and renal failure is very general critical illness all worldwide.According to U.S.'s kidney database displaying, the whole America in 2005, there is the end-stage renal failure patient who surpasses 450,000.In China, according to the incomplete statistics of Chinese nephropathy association, need at present the uremic patient for the treatment of nearly more than 1,000,000.It is to treat at present the applied main method of renal failure and uremia that using artificial kidney system is carried out extracorporeal circulation of blood purification, and corresponding extracorporeal circulation equipment is generally referred to as haemodialysis control unit.Device structure based on complicated and work process, hemodialysis function is removed the toxin in uremic patient body more effectively.But haemodialysis control unit and the pattern for the treatment of accordingly still have larger drawback at present, are mainly reflected in:
1) medical treatment cost is high
General haemodialysis control unit mainly comprises the parts such as dialysate supply unit, automatic monitoring system and extracorporeal blood circulation system.Dialysate supply unit comprises dynamical system and temperature-controlling system, and the former can automatic preparation electrolyte content approach the sterile dialysis liquid of human body, and the negative pressure of dialysis fluid circuit is provided; The main Maintenance dialysis liquid of the latter constant temperature is supplied with.Automatic monitoring device carries out safely arranging in order to guarantee the extracorporeal circulation of blood of dialysis procedure, generally by dialysis solution and blood flow rate regulator control system, dialysate concentration monitoring system, sound pulse pressure monitor system, leak blood monitor system etc. and partly form.Traditional haemodialysis control unit is by various executors, heat transmitter and the control system integration of realizing above function in one, and device structure is complicated, bulky, and hardware cost is high.In China and most of developing countries, generally only have medium-and-large-sized hospital just to there is the ability of buying and using haemodialysis control unit at present, popularize to treatment and brought many restrictions.
2) quality of life of patients is poor
Existing haemodialysis control unit build is huge, and need fixing using area, so current hemodialysis mode is main or so-called dialysis center hemodialysis (In-center hemodialysis), patient goes to hospital's dialysis center, dialyse weekly 2~3 times, dialyse several hours at every turn.Loaded down with trivial details so round treatment meeting severe jamming patient's routine work and life, reduction patient's quality of life, long-term treatment easily makes patient produce mental maladjustment.According to statistics, up to 27% hemodialysis patients, there is suicidal tendency.
In order to overcome the unfavorable factor of traditional hemodialysis pattern, academia and industrial quarters had once been launched a large amount of research, and had obtained a series of achievement, had proposed some advanced persons' treatment pattern, as " HHD " pattern, this mode allows patient to dialyse at home.Under HHD mode, the total dialysis time of patient increases, and more approaches people's physiological status; Because patient can carry out hemodialysis at night and time of having a rest, so greatly increase free time, patient can recover Job.Result of study shows, home dialysis all has larger advantage at aspects such as patient's life span, quality of lifes.But the popularization of advanced treatment pattern needs the support of therapeutic equipment, and current conventional hemodialysis (CHD) machine complex structure is bulky, and complex operation, patient grasp have great difficulty, the shortage of network function be also difficult to guarantee patient to emergency in time, correctly process.
Be applied to the alternative extracorporeal circulation equipment of liver and cardiac function and have equally Similar Problems, the portability of therapeutic equipment, intellectuality and networking are following inexorable trends, and need to meet low-cost requirement as far as possible.Industrial quarters and academia have successively proposed concept and the imagination of some equipment improvement, but mostly propose feasible technical method, do not support these to realize conceptually, can not tackle the problem at its root.
Summary of the invention
The object of the invention is to overcome the problems referred to above of the prior art, provide a kind of and can realize portability, networking and intelligentized separate type extracorporeal circulation system.
For overcoming the problems referred to above of the prior art, the present invention by the following technical solutions:
A kind of separate type extracorporeal circulation system, comprise master system, lower computer system and extracorporeal circulation apparatus, described master system is independent of lower computer system and extracorporeal circulation apparatus and exists, and between master system and lower computer system and between lower computer system and extracorporeal circulation apparatus, by wired or wireless data, is connected; Wherein, master system provides man machine operation interface, and formation processing program and instruction are also sent to slave computer; After slave computer is translated into control signal by received control instruction, direct control volume external circulating system moves; Extracorporeal circulation system returns to real-time status parameter by slave computer to host computer at run duration simultaneously; After host computer reception, in conjunction with the handling procedure judgement processing progress of setting or formation feedback command, change control instruction, important state parameter and information are sent to demonstration in real time on man machine operation interface simultaneously.
Further, described master system is portable computer or desk computer.
Further, described lower computer system is single-chip microcomputer or programmable logic controller (PLC).
Further, a kind of separate type extracorporeal circulation system of alternative renal function, comprise master system, lower computer system and extracorporeal circulation apparatus, described master system is independent of lower computer system and extracorporeal circulation apparatus exists, described extracorporeal circulation apparatus comprises dialyser, arterial blood interface, venous blood interface, displacement liquid interface, waste liquid interface, and connection arterial blood interface, venous blood interface, the arterial blood pipeline of waste liquid interface and dialyser, venous blood pipeline and waste liquid pipeline, on arterial blood pipeline, be provided with a threeway linker, between this threeway linker and displacement liquid interface, be provided with displacement liquid pipeline, displacement liquid seam is disposed with displacement liquid pump, attemperating unit and bubble trap, and arterial blood seam is disposed with tremulous pulse valve and blood pump, and venous blood seam is provided with venous valving, and waste liquid seam is provided with ultrafiltrate pump, described tremulous pulse valve, venous valving, blood pump, displacement liquid pump, ultrafiltrate pump, attemperating unit are all connected with lower computer system and are controlled by lower computer system, on waste liquid pipeline on arterial blood pipeline between described linker and dialyser, between ultrafiltrate pump and dialyser and be equipped with pressure transducer on the venous blood pipeline between venous valving and dialyser, on venous blood pipeline between described venous valving and dialyser, be also provided with temperature sensor and blood and leak sensor, described pressure transducer, temperature sensor and blood leak sensor and are connected with lower computer system and are controlled by lower computer system, described lower computer system is connected with master system and is controlled by master system.
Further, described blood pump, displacement liquid pump, ultrafiltrate pump are peristaltic pump, and described tremulous pulse valve, venous valving all adopt pinch valve, and described attemperating unit is silica gel heating device.
Compared with prior art, separate type extracorporeal circulation system of the present invention is realized the control unit of conventional bulk external circulating device with host computer and slave computer mode, and usings ripe microcomputer system as host computer, thereby makes system have following characteristic:
First, portability, relative conventional bulk outer circulation device, haemodialysis control unit particularly, separate type extracorporeal circulation system of the present invention will reduce the volume of equipment significantly, extracorporeal circulation equipment is easy to carry, is applicable to patient's repeatedly dialysis in short-term or nocturnal dialysis treatment at home, when reducing medical care cost, reduce dialysis patient in the dialysis toxin tolerance of interval;
Secondly, intellectuality can realize abundant application function on the platform of master system, is convenient to develop different control software, as artificial kidney, artificial liver or artificial heart etc. are controlled software; Interactive interface is friendly, and feedback data is timely, is conducive to improve man-machine interaction efficiency;
Again, networking, by the abundant ancillary equipment of master system and interface, as the network port, photographic head and other data communication port etc., can realize the networked control of therapeutic process, be convenient to realize expert's tele-medicine and instruct and assist, improve effect and the safety for the treatment of;
Finally, low cost, the host computer platform of producing in enormous quantities by application (as PC) realizes system and controls, and will avoid for the customized development of be pilot relatively and produce the too high problem of hardware and software cost causing.
Accompanying drawing explanation
Figure 1 shows that the structural representation of the separate type extracorporeal circulation system in the embodiment of the present invention.
The specific embodiment
In order to make object of the present invention, technical scheme and advantage clearer, below in conjunction with drawings and Examples, the present invention is further elaborated.Should be appreciated that specific embodiment described herein, only in order to explain the present invention, is not intended to limit the present invention.
As shown in Figure 1, the separate type extracorporeal circulation system of the alternative renal function in the present embodiment comprises extracorporeal circulation apparatus 1, master system 2 and lower computer system 3, wherein, extracorporeal circulation apparatus 1 becomes one with lower computer system 3, and master system 2 is independent to be existed.
Extracorporeal circulation apparatus 1 in the present embodiment comprises dialyser 11, arterial blood interface A, venous blood interface B, displacement liquid interface C, waste liquid interface D, and the arterial blood pipeline 12, venous blood pipeline 13 and the waste liquid pipeline 14 that are communicated with arterial blood interface A, venous blood interface B, waste liquid interface D and dialyser 11, on arterial blood pipeline 12, be provided with a threeway linker 4, between this threeway linker 4 and displacement liquid interface C, be provided with displacement liquid pipeline 15.Displacement liquid interface C place is disposed with displacement liquid pump C1, attemperating unit C2 and bubble trap C3, and arterial blood interface A place is disposed with tremulous pulse valve A1 and blood pump A2, and venous blood interface B place is provided with venous valving B1, and waste liquid interface D place is provided with ultrafiltrate pump D1, on arterial blood pipeline 12 between threeway linker 4 and dialyser 1, on venous blood pipeline 13 on waste liquid pipeline 14 between ultrafiltrate pump D1 and dialyser 1 and between venous valving B1 and dialyser 1, be respectively equipped with pressure transducer 5, 6, 7, on venous blood pipeline 13 between venous valving B1 and dialyser 1, be also provided with temperature sensor 8 and blood and leak sensor 9, tremulous pulse valve A1, venous valving B1, blood pump A2, displacement liquid pump C1, ultrafiltrate pump D1, attemperating unit C2, pressure transducer 5, 6, 7, temperature sensor 8 is leaked sensor 9 with blood and is all connected with lower computer system 3 and is controlled by lower computer system 3, lower computer system 3 is connected with master system 2 and is controlled by master system 2.
The separate type extracorporeal circulation system of the alternative renal function in the present embodiment is when work, by master system 2, send signal, signal transfers to lower computer system 3 and is given an order tremulous pulse valve A1 and blood pump A2 are opened by lower computer system 3, now, under the driving of blood pump A2, blood to be filtered enters arterial blood pipeline 12 in patient body, meanwhile, under the control of lower computer system 3, displacement liquid pump C1 opens, and drive displacement liquid to enter displacement liquid pipeline 15, enter the displacement liquid of displacement liquid pipeline 15 successively by changing liquid pump C1, attemperating unit C2, after bubble trap C3 and threeway linker 4 with enter arterial blood pipeline 12 and with its in blood to be filtered can and, the replaced liquid dilution of blood to be filtered, with the latter two, jointly enter in dialyser 11 and filter, effect due to ultrafiltrate pump D1, semipermeable membrane both sides mineralization pressure in dialyser 11 is poor, a part of blood plasma in blood to be filtered flows out semipermeable membrane under the driving of pressure differential, forming waste liquid discharges from waste liquid pipeline 14, cell in blood and albumen are retained in dialyser 11, and return in patient body by venous line 13.Along with the carrying out of circulation, the toxin in the blood to be filtered in patient body is discharged human body with waste liquid form gradually from waste liquid pipeline 14, reaches the object of blood purification.
In said process, the effect of pressure transducer 5,6,7 is to monitor in real time each ducted pressure, the effect of temperature sensor 8 is the temperature of the blood of monitoring in real time after dialyser 11 filters, the effect that blood leaks sensor 9 is the liquid flow in real-time monitoring tubular, while there is the situations such as bubble in monitored blood, gives the alarm.The testing result of each sensor is all fed back in master system 2 and in the man machine interface of master system 2 and is shown in real time by lower computer system 3, facilitate patient in conjunction with the handling procedure judgement processing progress of setting or make corresponding parameter adjustment according to data variation, guaranteeing that stable, the safety of filter process is carried out.
Master system 2 in the present embodiment can be portable computer or desk computer, and lower computer system 3 can be single-chip microcomputer or programmable logic controller (PLC).
For each performer contacts and pollutes with blood or displacement liquid, blood pump A2 in the present embodiment, displacement liquid pump C1, ultrafiltrate pump D1 all adopt peristaltic pump, tremulous pulse valve A1, venous valving B1 adopt pinch valve, and attemperating unit C2 adopts silica gel heating device, to guarantee that refusing liquid in pipeline directly contacts.
The separate type extracorporeal circulation system of the alternative renal function in the present embodiment, by master system 2 is independent, has reduced the volume of traditional extracorporeal circulation system significantly, makes extracorporeal circulation system realize portability; In addition, can also in master system 2, carry out corresponding programming for different blood purification demands, as artificial kidney, artificial liver or artificial heart-lung system operating software etc., or master system 2 is implemented to remote control, realize networking and the intellectuality of extracorporeal circulation system; Finally, the host computer platform of producing in enormous quantities by application realizes system and controls, to avoid conventional needle to the customized development of be pilot relatively and produce the too high problem of hardware and software cost causing, thereby reduce system cost, promoting the universal of external circulating therapy.
In practical application, only the dialyser of extracorporeal circulation apparatus 1 11 need be replaced with to oxygen-increasing device, the separate type extracorporeal circulation system of the alternative renal function in the present embodiment just becomes the separate type extracorporeal circulation system that substitutes cardio-pulmonary function, i.e. artificial heart-lung can be by the cardiopulmonary substituted device in operating; If the waste liquid interface D place of circulating device 1 is provided with an adsorbent equipment in vitro, and between waste liquid interface D and dialyser 11, be provided with a return duct, the waste liquid that makes to be derived by waste liquid interface D carries out harmful substance absorption through adsorbent equipment again leads and gets back in dialyser 11 by return duct, separate type extracorporeal circulation system in the present embodiment becomes the separate type extracorporeal circulation system that substitutes liver function, it is artificial liver, certainly, can also to the structure of extracorporeal circulation apparatus 1, improve to meet different blood filtration occasions as required.
As another embodiment, can select the lower computer system in the present embodiment 3 and extracorporeal circulation apparatus 1 independently, the effect of this embodiment is consistent with the effect of the separate type extracorporeal circulation system of alternative renal function in the present embodiment.
Those of ordinary skill in the art will appreciate that, embodiment described here is in order to help reader understanding's principle of the present invention, should be understood to that protection scope of the present invention is not limited to such special statement and embodiment.Those of ordinary skill in the art can make various other various concrete distortion and combinations that do not depart from essence of the present invention according to these technology enlightenments disclosed by the invention, and these distortion and combination are still in protection scope of the present invention.

Claims (6)

1. a separate type extracorporeal circulation system, comprise master system, lower computer system and extracorporeal circulation apparatus, it is characterized in that: described master system is independent of lower computer system and extracorporeal circulation apparatus and exists, between master system and lower computer system and between lower computer system and extracorporeal circulation apparatus, by wired or wireless data, be connected; Wherein, master system provides man machine operation interface, and formation processing program and instruction are also sent to slave computer; After slave computer is translated into control signal by received control instruction, direct control volume external circulating system moves; Extracorporeal circulation system returns to real-time status parameter by slave computer to host computer at run duration simultaneously; After host computer reception, in conjunction with the handling procedure judgement processing progress of setting or formation feedback command, change control instruction, important state parameter and information are sent to demonstration in real time on man machine operation interface simultaneously.
2. separate type extracorporeal circulation system according to claim 1, is characterized in that: described master system is portable computer or desk computer.
3. separate type extracorporeal circulation system according to claim 1 and 2, is characterized in that: described lower computer system is single-chip microcomputer or programmable logic controller (PLC).
4. the separate type extracorporeal circulation system of the alternative renal function of the separate type extracorporeal circulation system based on described in claim 1~3 any one claim, it is characterized in that: comprise master system, lower computer system and extracorporeal circulation apparatus, described master system is independent of lower computer system and extracorporeal circulation apparatus exists, described extracorporeal circulation apparatus comprises dialyser, arterial blood interface, venous blood interface, displacement liquid interface, waste liquid interface, and connection arterial blood interface, venous blood interface, the arterial blood pipeline of waste liquid interface and dialyser, venous blood pipeline and waste liquid pipeline, on arterial blood pipeline, be provided with a threeway linker, between this threeway linker and displacement liquid interface, be provided with displacement liquid pipeline, displacement liquid seam is disposed with displacement liquid pump, attemperating unit and bubble trap, and arterial blood seam is disposed with tremulous pulse valve and blood pump, and venous blood seam is provided with venous valving, and waste liquid seam is provided with ultrafiltrate pump, described tremulous pulse valve, venous valving, blood pump, displacement liquid pump, ultrafiltrate pump, attemperating unit are all connected with lower computer system and are controlled by lower computer system, on waste liquid pipeline on arterial blood pipeline between described linker and dialyser, between ultrafiltrate pump and dialyser and be equipped with pressure transducer on the venous blood pipeline between venous valving and dialyser, on venous blood pipeline between described venous valving and dialyser, be also provided with temperature sensor and blood and leak sensor, described pressure transducer, temperature sensor and blood leak sensor and are connected with lower computer system and are controlled by lower computer system, described lower computer system is connected with master system and is controlled by master system.
5. the separate type extracorporeal circulation system of alternative renal function according to claim 4, is characterized in that: described blood pump, displacement liquid pump, ultrafiltrate pump are peristaltic pump.
6. separate type extracorporeal circulation system according to claim 4, is characterized in that: described attemperating unit is silica gel heating device.
CN201310617436.0A 2013-11-27 2013-11-27 Separate-type extracorporeal circulation system Pending CN103585684A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104983410A (en) * 2014-10-31 2015-10-21 中国科学院苏州生物医学工程技术研究所 Electronic sphygmomanometer used for extracorporeal circulation equipment
CN110312567A (en) * 2017-02-22 2019-10-08 费森尤斯医疗保健控股公司 For using the dialyzer pressure of measurement to estimate the system and method for dialyzer flow rate

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Publication number Priority date Publication date Assignee Title
US5658240A (en) * 1992-03-04 1997-08-19 Cobe Laboratories, Inc. Blood component collection system with optimizer
JP2009034543A (en) * 2008-10-21 2009-02-19 Teijin Ltd Home dialysis supporting system
CN101797404A (en) * 2009-12-29 2010-08-11 华南理工大学 Remote monitoring system of peritoneal dialysis machines and monitoring method thereof
CN201755338U (en) * 2010-02-02 2011-03-09 华南理工大学 Household peritoneal dialysis treatment device
WO2011080186A1 (en) * 2009-12-28 2011-07-07 Gambro Lundia Ab Controlling an apparatus for fluid transfer to and/or from a subject
CN102389594A (en) * 2011-08-04 2012-03-28 黄昱 Portable blood purifying system

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5658240A (en) * 1992-03-04 1997-08-19 Cobe Laboratories, Inc. Blood component collection system with optimizer
JP2009034543A (en) * 2008-10-21 2009-02-19 Teijin Ltd Home dialysis supporting system
WO2011080186A1 (en) * 2009-12-28 2011-07-07 Gambro Lundia Ab Controlling an apparatus for fluid transfer to and/or from a subject
CN101797404A (en) * 2009-12-29 2010-08-11 华南理工大学 Remote monitoring system of peritoneal dialysis machines and monitoring method thereof
CN201755338U (en) * 2010-02-02 2011-03-09 华南理工大学 Household peritoneal dialysis treatment device
CN102389594A (en) * 2011-08-04 2012-03-28 黄昱 Portable blood purifying system

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104983410A (en) * 2014-10-31 2015-10-21 中国科学院苏州生物医学工程技术研究所 Electronic sphygmomanometer used for extracorporeal circulation equipment
CN104983410B (en) * 2014-10-31 2018-05-29 中国科学院苏州生物医学工程技术研究所 A kind of electronic sphygmomanometer in extracorporeal circulation equipment
CN110312567A (en) * 2017-02-22 2019-10-08 费森尤斯医疗保健控股公司 For using the dialyzer pressure of measurement to estimate the system and method for dialyzer flow rate
CN110312567B (en) * 2017-02-22 2020-12-08 费森尤斯医疗保健控股公司 System and method for estimating dialyzer flow rate using measured dialyzer pressure

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