CN102670186A - Venous pressure measuring probe as well as mounting method and use method thereof - Google Patents

Venous pressure measuring probe as well as mounting method and use method thereof Download PDF

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Publication number
CN102670186A
CN102670186A CN2012101605500A CN201210160550A CN102670186A CN 102670186 A CN102670186 A CN 102670186A CN 2012101605500 A CN2012101605500 A CN 2012101605500A CN 201210160550 A CN201210160550 A CN 201210160550A CN 102670186 A CN102670186 A CN 102670186A
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installation end
venous pressure
pressure measuring
measuring probe
optical fiber
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CN102670186B (en
Inventor
孔德润
许建明
吴艾久
何兵兵
张磊
孙斌
许晓勇
王进广
余芳芳
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Hefei Zhongna Medical Instrument Co ltd
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First Affiliated Hospital of Anhui Medical University
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Abstract

The invention discloses a venous pressure measuring probe as well as a mounting method and a use method thereof. The venous pressure measuring probe comprises a flexible liner, a rigid shell and a stress transfer medium, wherein the liner is filled with the stress transfer medium; the liner is mounted on the shell; the liner comprises a bracket, an optical fiber pressure sensor, an optical fiber lead and a cylindrical film cylinder; the film cylinder is sleeved on the bracket; a sealing cavity is formed by the film cylinder and the bracket; the optical fiber pressure sensor is in optical hot-melting connection with the optical fiber lead; the optical fiber pressure sensor is accommodated in the sealing cavity; and the optical fiber lead passes through the liner and extends out of the bracket. The venous pressure measuring probe has the advantages that the venous pressure measuring probe is small in size, so that a pressure measuring operation can be performed by inserting the venous pressure measuring probe into a detected part in human body by virtue of a medical endoscope and a biopsy tool channel; the venous pressure measuring probe can serve as a key part of a non-invasive venous pressure measuring device; and the venous pressure measuring probe is suitable for an effective non-invasive detecting device for measuring venous pressure in human body.

Description

A kind of venous pressure measuring probe and installation method thereof, method for using
Technical field
The present invention relates to the fluid pressure detection range, relate in particular to a kind of venous pressure measuring probe that clinical medicine is used that adapts to.
Background technology
During modern medicine is clinical human body being carried out the venous pressure monitoring, is a significant inspection technology.Usually the inspection technology that adopts is the initiative pressure measurement that imports; This pressure measurement mainly contains dual mode; A kind of is that the introducing conduit of pressure tester is inserted vein blood vessel through Minimally Invasive Surgery, through the blood pressure in the inflow catheter being adopted the contrast of cross over pipe hydraulic pressure, measuring and calculating mean blood pressure value; Another kind of mode is, with the micro pressure sensor that occurs in recent years, through directly measuring pressure value in the puncture intervention vein blood vessel.
The common defects of aforesaid way is; The pressure measurement operation must destroy the vein blood vessel tube wall and cause wound, though can not produce serious consequence generally speaking, carries out initiative venous pressure measurement for getting involved human internal organs and internal organs; Especially higher to venous pressure; Local when cirsoid situation occurring, initiative measurement possibly cause wound to heal voluntarily causing massive hemorrhage, and this is a taboo project in clinical practice usually.
Summary of the invention
In view of this, be necessary to provide a kind of venous pressure measuring probe, under based on present pressure sensor application technological accumulation and inheritance, through non-invasive pressure measurement mode, realize accurately gathering inside of human body venous pressure value, its key is the design of measuring probe.
The present invention is achieved in that a kind of venous pressure measuring probe, and it comprises:
Flexible inner bag, this inner bag comprises:
Support; It comprises first installation end, second installation end and the connecting rod that connects this first installation end and this second installation end; This first installation end and this second installation end are positioned at the same side of this connecting rod; This first installation end and this second installation end all are smooth hemisphere head, and the ball of this first installation end backs down and is provided with the transmitting medium entrance hole, and the ball of this second installation end backs down and is provided with the first optical fiber leadout hole;
Fibre optic compression sensor, it is between this first installation end and this second installation end;
Optic fibre wire, this fibre optic compression sensor are fixed on this optic fibre wire and make the optics hot melt with this optic fibre wire and be connected, and this optic fibre wire extends the ball top of this second installation end via this first optical fiber leadout hole;
Tubular thin film cylinder; It accommodates this support; The two ends of this thin film cylinder and this first installation end and this second installation end are fixed; This thin film cylinder, this first installation end and this second installation end form an annular seal space, and this fibre optic compression sensor is housed in the sealing intracavity, and this transmitting medium entrance hole communicates with the sealing chamber; And
Stiff case; This housing comprises end, package cover and connects this end and this package cover and the tubular accepting groove of opening; This end is smooth hemisphere head, and this package cover can be separated with this accepting groove engaging, and the top of this package cover vertically stretches out and becomes to be threaded post; The post that is threaded offers the second optical fiber leadout hole that communicates with this accepting groove; The cross section of this accepting groove is curved, and this inner bag is sticked in this accepting groove, be exposed to this accepting groove outer should in cholic outer surface form flexible test surface; This first optical fiber leadout hole is located along the same line and communicates with this second optical fiber leadout hole, and this optic fibre wire also extends the ball top of this package cover via this second optical fiber leadout hole; And
The stress transmitting medium, it is full of cholic sealing chamber in this.
As the further improvement of such scheme, this stress transmitting medium is a normal saline.
As the further improvement of such scheme, this connecting rod is strip.
As the further improvement of such scheme, the two ends of this connecting rod are tangent with this first installation end, this second installation end respectively.
As the further improvement of such scheme, it is material that this housing adopts titanium, aluminium alloy.
As the further improvement of such scheme, be provided with between this inner bag and this accepting groove this inner bag is stabilized in the viscose on this accepting groove.
As the further improvement of such scheme, this thin film cylinder is transparence.
As the further improvement of such scheme, this thin film cylinder is the polyurethane layer of thickness 0.03mm.
The present invention also provides the installation method of above-mentioned venous pressure measuring probe, and this installation method may further comprise the steps:
With fibre optic compression sensor and the optic fibre wire that is connected thereof; Inboard from second installation end of internal bladder support outwards passes; The joint portion of pick off and optic fibre wire is fixed on first optical fiber leadout hole inboard; Gap between the hermetic fiber lead and the first optical fiber leadout hole makes pick off support through its optic fibre wire that is connected and places on the axis of second installation end simultaneously;
Tubular thin film cylinder cover is rolled in the internal bladder support that comprises first installation end and second installation end, and leveling tubular thin film cylinder also keeps the pellicular front equalization of strain;
Two ports of tubular thin film cylinder are bonding with first installation end and second installation end of support respectively; Be axial symmetric ball shape after tubular thin film cylinder and support are bonding; Its first installation end place leaves the transmitting medium entrance hole, and optic fibre wire is drawn at the second installation end place;
The stress transmitting medium is injected inner bag through the transmitting medium entrance hole; Reach full state until it; Clog the transmitting medium entrance hole then, make it form the inner bag with annular seal space, the cylinder zone that the sealing chamber is filled the stress transmitting medium promptly can be used as test surface;
Inner bag inserted from the rear end of main casing installs, again package cover is connected on the main casing through patching groove from the inner bag second installation end place, in cholic second installation end optic fibre wire of drawing derive through the second optical fiber fairlead.
The present invention also provides the method for using of above-mentioned venous pressure measuring probe, and this method for using may further comprise the steps:
With the flexible test surface of this measuring probe, ride over measured vein blood vessel surface by post to parallel mode, and apply applied external force perpendicular to test surface, promptly measure external force, make the thin film of this flexibility test surface that concavo-convex deformation take place;
When venous pressure was higher than normal pressure, recessed deformation took place in this thin film;
The spatial volume of measuring probe generation deformation and the blood pressure pressure of internal blood vessel are the linear with joint efforts of three kinds of active forces of measurement external force of applying of vein pressure, blood vessel surface tension force and operation; Wherein measuring external force acquires a certain degree; When being the whole pressings of flexible test surface to blood vessel surface; The numerical value of making a concerted effort that measurement is read keeps relative stability, and the numerical value of making a concerted effort of above-mentioned three kinds of active forces is outputed to data analysis device, in data analysis device; Through the algorithm routine calculating acquisition internal blood vessel force value of operation by the empirical model design, i.e. venous pressure value.
Venous pressure measuring probe provided by the invention adapts to clinical medicine and uses; It has the liquid medium of identical internal stress; During through the relative pressing of compliant interface after encapsulating separately; Its zone that is in contact with one another overcomes surface tension generation deformation, and deformation causes the medium internal stress to be transmitted and tend to be balanced to low by height.Because volume of the present invention is small; Can and be deep into inside of human body by medical endoscope and survey position enforcement pressure measurement operation through its biopsy tool passage; Can be used as the critical component of non-invasive venous pressure measuring device, adapt to the inside of human body venous pressure is measured, effective no-invasive property sniffer.
Description of drawings
The schematic perspective view of the venous pressure measuring probe that Fig. 1 provides for preferred embodiments of the present invention.
Fig. 2 is the inner-tube structure sketch map of Fig. 1 medium-sized vein blood pressure measurement probe.
Fig. 3 be among Fig. 2 in cholic supporting structure sketch map.
Fig. 4 is the shell structure sketch map of Fig. 1 medium-sized vein blood pressure measurement probe.
Main symbol description
Figure BDA0000167119471
The specific embodiment
In order to make the object of the invention, technical scheme and advantage clearer,, the present invention is further elaborated below in conjunction with accompanying drawing and embodiment.Should be appreciated that specific embodiment described herein only in order to explanation the present invention, and be not used in qualification the present invention.
Please consult Fig. 1 and Fig. 2 in the lump, the structural representation of the venous pressure measuring probe that it provides for preferred embodiments of the present invention.The venous pressure measuring probe comprises flexible inner bag 1, stiff case 2 and stress transmitting medium (indicating), and wherein, the stress transmitting medium riddles in the inner bag 1, and inner bag 1 is installed on the housing 2.In this embodiment; The stress transmitting medium is liquid normal saline (concentration is 0.9% NaCl aqueous solution); Certainly can also be other liquid medium harmless in other embodiments, as select the methyl-silicone oil (Silicone Oil) etc. of the low coefficient of viscosity and higher resistance to compression for use human non-toxic.
Please combine Fig. 3 and Fig. 4, inner bag 1 comprises support 20, fibre optic compression sensor 4, optic fibre wire 3 and tubular thin film cylinder 26.
Support 20 comprises first installation end 11, second installation end 13 and the connecting rod 12 that connects first installation end 11 and second installation end 13.In this embodiment, connecting rod 12 is strip, and the two ends of connecting rod 12 are tangent with first installation end 11, second installation end 13 respectively, and first installation end 11 and second installation end 13 are positioned at the same side of connecting rod 12.First installation end 11 and second installation end 13 all are smooth hemisphere head, and the ball of first installation end 11 backs down the ball that is provided with transmitting medium entrance hole 14, the second installation ends 13 and backs down and be provided with the first optical fiber leadout hole 15.
Fibre optic compression sensor 4 is between first installation end 11 and second installation end 13; Fibre optic compression sensor 4 is fixed on the optic fibre wire 3 and with optic fibre wire 3 and electrically connects; Refer to that mainly making the optics hot melt connects, optic fibre wire 3 extends the ball top of second installation end 13 via the first optical fiber leadout hole 15.
Tubular thin film cylinder 26 is accommodated support 20; The two ends of thin film cylinder 26 and first installation end 11 and second installation end 13 are fixing; Thin film cylinder 26, first installation end 11 and second installation end 13 form an annular seal space 10; Fibre optic compression sensor 4 is housed in the annular seal space 10, and transmitting medium entrance hole 14 communicates with annular seal space 10.Preferably, thin film cylinder 26 is the polyurethane layer of thickness 0.03mm, is transparence.
It is material that housing 2 adopts titanium, aluminium alloy, and housing 2 comprises end 31, package cover 33 and connects end 31 and package cover 33 and the tubular accepting groove 32 of opening.End 31 is smooth hemisphere head.Package cover 33 can be separated with accepting groove 32 engagings, and it is a variety of that the mode of engaging has, and in this embodiment, adopts the mode of conventional inserting groove 36 engagings.The top of package cover 33 vertically stretches out and becomes to be threaded post 37, and the post 37 that is threaded offers the second optical fiber leadout hole 35 that communicates with accepting groove 32, and the cross section of accepting groove 32 is curved.
The venous pressure measuring probe encapsulates (being 20 ℃ of normal pressure and temperature environment 101325Pa) under normal conditions and gets final product when mounted, and its installation steps are following:
With fibre optic compression sensor 4 and the optic fibre wire 3 that is connected thereof; Inboard from second installation end 13 of internal bladder support 20 outwards passes; The joint portion of pick off 4 and optic fibre wire 3 is fixed on the first optical fiber leadout hole, 15 inboards (in this embodiment; Adopt hot melt material fixing as: high density polyethylene (HDPE)), the gap between hermetic fiber lead 3 and the first optical fiber leadout hole 15 makes pick off 4 place on the axis of second installation end 13 through its optic fibre wire that is connected 3 supports simultaneously;
Tubular thin film cylinder 26 covers are rolled in the internal bladder support 20 that comprises first installation end 11 and second installation end 13, and leveling tubular thin film cylinder 26 also keeps the pellicular front equalization of strain;
Two ports of tubular thin film cylinder 26 are bonding (in this embodiment with first installation end 11 and second installation end 13 of internal bladder support 20 respectively; Bonding medium adopt chemical material as: ECA); Be axial symmetric ball shape after tubular thin film cylinder 26 and internal bladder support 20 are bonding; Its first installation end, 11 places leave transmitting medium entrance hole 14, the second installation ends 13 places and draw optic fibre wire 3;
The stress transmitting medium is annotated 14 through the transmitting medium entrance hole go into inner bag; Reach full state until it; Clog transmitting medium entrance hole 14 then (in this embodiment; Adopt hot melt material as: high density polyethylene (HDPE) filling transmitting medium entrance hole 14), make it form the inner bag 1 with annular seal space 10, the cylinder zone that the annular seal space 10 of this inner bag 1 is filled the stress transmitting medium promptly can be used as test surface (in this embodiment, being the rectangle curved surface);
Inner bag 1 is mounted to correct position from the insertion of the rear end of main casing; Again package cover is connected on the housing 2 through patching groove (figure do not show) from the inner bag second installation end place, in cholic second installation end 13 optic fibre wire 3 of drawing derive through the second optical fiber fairlead 15.
At this moment, this venous pressure measuring probe installs.In this embodiment; For inner bag 1 can better be stabilized between accepting groove 32; Be provided with viscose between inner bag 1 and the accepting groove 32, certainly in other embodiments, this viscose can not adopt yet; Flexibility and accepting groove 32 self rigidity through inner bag 1 self combine; While can well be firm between inner bag 1 and the accepting groove 32 by end, package cover and accepting groove 32 cooperation each other, can not influence the normal use of this venous pressure measuring probe.
This venous pressure measuring probe in use; With the flexible test surface of this measuring probe, ride over measured vein blood vessel surface by post to parallel mode, and apply applied external force perpendicular to test surface; Promptly measure external force, make the thin film of this flexibility test surface that concavo-convex deformation take place;
When venous pressure was higher than normal pressure, recessed deformation took place in this thin film;
The spatial volume of measuring probe generation deformation and the blood pressure pressure of internal blood vessel are the linear with joint efforts of three kinds of active forces of measurement external force of applying of vein pressure, blood vessel surface tension force and operation; Wherein measuring external force acquires a certain degree; When being the whole pressings of flexible test surface to blood vessel surface; The numerical value of making a concerted effort that measurement is read keeps relative stability; The numerical value of making a concerted effort of above-mentioned three kinds of active forces is outputed to data analysis device (in this embodiment, referring to a kind of digital terminal equipment based on microprocessor control special in the industry), in data analysis device; Through the algorithm routine calculating acquisition internal blood vessel force value of operation by the empirical model design, i.e. venous pressure value.
This venous pressure measuring probe adapts to clinical medicine and uses; It has the liquid medium of identical internal stress; During through the relative pressing of compliant interface after the encapsulation separately, its zone that is in contact with one another overcomes surface tension generation deformation, and deformation causes the medium internal stress to be transmitted and tend to be balanced to low by height.Because volume of the present invention is small; Can and be deep into inside of human body by medical endoscope and survey position enforcement pressure measurement operation through its biopsy tool passage; Can be used as the critical component of non-invasive venous pressure measuring device, adapt to the inside of human body venous pressure is measured, effective no-invasive property sniffer.
The above is merely preferred embodiment of the present invention, not in order to restriction the present invention, all any modifications of within spirit of the present invention and principle, being done, is equal to and replaces and improvement etc., all should be included within protection scope of the present invention.

Claims (10)

1. venous pressure measuring probe is characterized in that it comprises:
Flexible inner bag, this inner bag comprises:
Support; It comprises first installation end, second installation end and the connecting rod that connects this first installation end and this second installation end; This first installation end and this second installation end are positioned at the same side of this connecting rod; This first installation end and this second installation end all are smooth hemisphere head, and the ball of this first installation end backs down and is provided with the transmitting medium entrance hole, and the ball of this second installation end backs down and is provided with the first optical fiber leadout hole;
Fibre optic compression sensor, it is between this first installation end and this second installation end;
Optic fibre wire, this fibre optic compression sensor are fixed on this optic fibre wire and make the optics hot melt with this optic fibre wire and be connected, and this optic fibre wire extends the ball top of this second installation end via this first optical fiber leadout hole;
Tubular thin film cylinder; It accommodates this support; The two ends of this thin film cylinder and this first installation end and this second installation end are fixed; This thin film cylinder, this first installation end and this second installation end form an annular seal space, and this fibre optic compression sensor is housed in the sealing intracavity, and this transmitting medium entrance hole communicates with the sealing chamber; And
Stiff case; This housing comprises end, package cover and connects this end and this package cover and the tubular accepting groove of opening; This end is smooth hemisphere head, and this package cover can be separated with this accepting groove engaging, and the top of this package cover vertically stretches out and becomes to be threaded post; The post that is threaded offers the second optical fiber leadout hole that communicates with this accepting groove; The cross section of this accepting groove is curved, and this inner bag is sticked in this accepting groove, be exposed to this accepting groove outer should in cholic outer surface form flexible test surface; This first optical fiber leadout hole is located along the same line and communicates with this second optical fiber leadout hole, and this optic fibre wire also extends the ball top of this package cover via this second optical fiber leadout hole; And
The stress transmitting medium, it is full of cholic sealing chamber in this.
2. a kind of venous pressure measuring probe as claimed in claim 1 is characterized in that this stress transmitting medium is a normal saline.
3. a kind of venous pressure measuring probe as claimed in claim 1 is characterized in that this connecting rod is strip.
4. like claim 1 or 3 described a kind of venous pressure measuring probes, it is characterized in that the two ends of this connecting rod are tangent with this first installation end, this second installation end respectively.
5. a kind of venous pressure measuring probe as claimed in claim 1 is characterized in that, it is material that this housing adopts titanium, aluminium alloy.
6. a kind of venous pressure measuring probe as claimed in claim 1 is characterized in that, is provided with between this inner bag and this accepting groove this inner bag is stabilized in the viscose on this accepting groove.
7. a kind of venous pressure measuring probe as claimed in claim 1 is characterized in that this thin film cylinder is transparence.
8. like claim 1 or 7 described a kind of venous pressure measuring probes, it is characterized in that this thin film cylinder is the polyurethane layer of thickness 0.03mm.
9. the installation method of a venous pressure measuring probe, it is applied to it is characterized in that like any described venous pressure measuring probe in the claim 1 to 8 this installation method may further comprise the steps:
With fibre optic compression sensor and the optic fibre wire that is connected thereof; Inboard from second installation end of internal bladder support outwards passes; The joint portion of pick off and optic fibre wire is fixed on first optical fiber leadout hole inboard; Gap between the hermetic fiber lead and the first optical fiber leadout hole makes pick off support through its optic fibre wire that is connected and places on the axis of second installation end simultaneously;
Tubular thin film cylinder cover is rolled in the internal bladder support that comprises first installation end and second installation end, and leveling tubular thin film cylinder also keeps the pellicular front equalization of strain;
Two ports of tubular thin film cylinder are bonding with first installation end and second installation end of support respectively; Be axial symmetric ball shape after tubular thin film cylinder and support are bonding; Its first installation end place leaves the transmitting medium entrance hole, and optic fibre wire is drawn at the second installation end place;
The stress transmitting medium is injected inner bag through the transmitting medium entrance hole; Reach full state until it; Clog the transmitting medium entrance hole then, make it form the inner bag with annular seal space, the cylinder zone that the sealing chamber is filled the stress transmitting medium promptly can be used as test surface;
Inner bag inserted from the rear end of main casing installs, again package cover is connected on the main casing through patching groove from the inner bag second installation end place, in cholic second installation end optic fibre wire of drawing derive through the second optical fiber fairlead.
10. the method for using of a venous pressure measuring probe, it is applied to it is characterized in that like any described venous pressure measuring probe in the claim 1 to 8 this method for using may further comprise the steps:
With the flexible test surface of this measuring probe, ride over measured vein blood vessel surface by post to parallel mode, and apply applied external force perpendicular to test surface, promptly measure external force, make the thin film of this flexibility test surface that concavo-convex deformation take place;
When venous pressure was higher than normal pressure, recessed deformation took place in this thin film;
The spatial volume of measuring probe generation deformation and the blood pressure pressure of internal blood vessel are the linear with joint efforts of three kinds of active forces of measurement external force of applying of vein pressure, blood vessel surface tension force and operation; Wherein measuring external force acquires a certain degree; When being the whole pressings of flexible test surface to blood vessel surface; The numerical value of making a concerted effort that measurement is read keeps relative stability, and the numerical value of making a concerted effort of above-mentioned three kinds of active forces is outputed to data analysis device, in data analysis device; Through the algorithm routine calculating acquisition internal blood vessel force value of operation by the empirical model design, i.e. venous pressure value.
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CN102908133A (en) * 2012-11-12 2013-02-06 合肥优尔电子科技有限公司 Esophagus vein blood pressure measuring instrument
CN105433929A (en) * 2015-12-31 2016-03-30 合肥优尔电子科技有限公司 Probing conduit for optical fiber pressure measuring device
CN105662386A (en) * 2015-12-31 2016-06-15 合肥优尔电子科技有限公司 Voltage detecting probe of optical fiber voltage detecting device
CN109069034A (en) * 2016-02-23 2018-12-21 波士顿科学国际有限公司 Pressure-sensing godet system including optical conenctor cable
CN110180763A (en) * 2019-05-29 2019-08-30 合肥中纳医学仪器有限公司 A kind of completion method film build method of probe and probe using film build method manufacture

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CN105433929A (en) * 2015-12-31 2016-03-30 合肥优尔电子科技有限公司 Probing conduit for optical fiber pressure measuring device
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CN110180763A (en) * 2019-05-29 2019-08-30 合肥中纳医学仪器有限公司 A kind of completion method film build method of probe and probe using film build method manufacture

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