CA2535452A1 - Vascular wound closure device - Google Patents

Vascular wound closure device Download PDF

Info

Publication number
CA2535452A1
CA2535452A1 CA002535452A CA2535452A CA2535452A1 CA 2535452 A1 CA2535452 A1 CA 2535452A1 CA 002535452 A CA002535452 A CA 002535452A CA 2535452 A CA2535452 A CA 2535452A CA 2535452 A1 CA2535452 A1 CA 2535452A1
Authority
CA
Canada
Prior art keywords
delivery tube
locking member
pusher member
tube
protuberance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002535452A
Other languages
French (fr)
Other versions
CA2535452C (en
Inventor
Yong Hua Zhu
Wolff M. Kirsch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Loma Linda University
Original Assignee
Loma Linda University Medical Center
Yong Hua Zhu
Wolff M. Kirsch
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Loma Linda University Medical Center, Yong Hua Zhu, Wolff M. Kirsch filed Critical Loma Linda University Medical Center
Priority to CA2801969A priority Critical patent/CA2801969C/en
Publication of CA2535452A1 publication Critical patent/CA2535452A1/en
Application granted granted Critical
Publication of CA2535452C publication Critical patent/CA2535452C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00491—Surgical glue applicators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/02—Surgical instruments, devices or methods, e.g. tourniquets for holding wounds open; Tractors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A61B2017/00637—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect for sealing trocar wounds through abdominal wall
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A61B2017/00646—Type of implements
    • A61B2017/00654—Type of implements entirely comprised between the two sides of the opening

Abstract

An apparatus (430) for closing a vascular wound includes an apparatus that can be threaded over a guidewire(458) into place at or adjacent the wound. The apparatus includes a chamber(520) that encloses a hemostatic material (270) therein. When the apparatus is positioned adjacent the wound as desired, the hemostatic material is deployed from the chamber. Blood contacts the hemostatic material, and blood clotting preferably is facilitated by a hemostatic agent within the material. Thus, the vascular puncture wound is sealed by blood clot formation.

Claims (34)

1. An apparatus for subcutaneously delivering a material, comprising:
an elongate delivery tube having a chamber configured to accommodate a material therewithin;
an elongate pusher member having a distal portion configured to slidably extend through at least a portion of the delivery tube so as to push at least a portion of the material out of the delivery tube, the pusher member having at least one protuberance;
a flexible locking member configured to fit at least partially around the pusher member and adapted to expand in a transverse direction when subjected to generally longitudinal compression;
wherein the flexible locking member is disposed adjacent the pusher member protuberance so that when the locking member is subjected to generally longitudinal compression, the locking member expands transversely to engage the pusher member protuberance to increase friction between the pusher member and the locking member so that the pusher member is restrained from moving relative to the locking member.
2. The apparatus of Claim 1, wherein the flexible locking member is configured to engage a proximal end of the delivery tube.
3. The apparatus of Claim 2 additionally comprising a locking cap configured to selectively compress the flexible locking member between the cap and the proximal end of the delivery tube.
4. The apparatus of Claim 3, wherein the locking cap is selectively engageable with the delivery tube.
5. The apparatus of Claim 1, wherein the locking member is substantially ring-shaped.
6. The apparatus of Claim 1, wherein the protuberance comprises an annular ring projecting from a surface of the pusher member.
7. The apparatus of Claim 1, wherein the protuberance comprises at least one bump projecting from a surface of the pusher member.
8. The apparatus of Claim 1, wherein a surface of the pusher member comprises a pit formed therein, and the protuberance projects from the pit.
9. The apparatus of Claim 1, wherein the protuberance extends outwardly between about 0.05-0.3 mm.
10. The apparatus of Claim 1, wherein the protuberance extends outwardly between about 0.1-0.2 mm.
11. The apparatus of Claim 1, wherein the material comprises a hemostatic material.
12. The apparatus of Claim 11, wherein the material is hydrophilic.
13. The apparatus of Claim 12, wherein the material is fibrous.
14. The apparatus of Claim 13, wherein the material comprises a chitosan fleece.
15. The apparatus of Claim 14, wherein the material comprises a chitosan fleece and a starch.
16. The apparatus of Claim 12, wherein the material comprises chitosan.
17. The apparatus of Claim 1, wherein the delivery tube comprises a plurality of elongate tube members configured to move between an engaged closed position and an open position
18. The apparatus of Claim 17, wherein the tube members axe flexible, and additionally comprising a flexible collar disposed about the tube members, the collar being biased to hold the tube members in the closed position.
19. The apparatus of Claim 17, wherein the collar is slidable over the delivery tube.
20. The apparatus of Claim 17 additionally comprising an elongate catheter, and the delivery tube chamber is configured to accept the catheter extending therethrough and also to accommodate material therein.
21. The apparatus of Claim 20, wherein the catheter comprises a hole formed through a side wall of the catheter, arid the delivery tube is arranged on the catheter so that a distal end of the tube is proximal the side hole.
22. The apparatus of Claim 21, wherein the distal end of the delivery tube is between about 5-1.5mm from the catheter side hole.
23. The apparatus of Claim 21, wherein the distal end of the delivery tube is arranged a distance from the side hole at least three times the thickness of the blood vessel wall.
24. A system for subcutaneously delivering a material, comprising:

an elongate delivery tube having a chamber configured to accommodate a material therewithin, a distal portion of the delivery tube having a smaller diameter than a proximal portion of the delivery tube;
an elongate pusher member having a distal portion configured to slidably extend through at least a portion of the delivery tube so as to push at least a portion of the material out of the delivery tube, a portion of the pusher member having a diameter less than the proximal portion of the delivery tube but greater than the distal portion of the delivery tube so that when the pusher is moved distally relative to the delivery tube, the pusher engages an inner surface of the distal portion of the delivery tube and deforms the delivery tube;
a flexible locking member configured to fit at least partially around the pusher member and adapted to expand in a transverse direction when subjected to generally longitudinal compression;
wherein the flexible locking member is disposed adjacent the pusher member so that when the locking member is subjected to generally longitudinal compression, the locking member expands transversely to engage the pusher member to increase friction between the pusher member and the locking member
25. The system of Claim 24, wherein the delivery tube comprises a plurality of segments coupled together.
26. The system of Claim 25, wherein the inner surface of the delivery tube tapers toward a distal end of the delivery tube.
27. The system of Claim 26, wherein when the pusher member is advanced distally relative o the tube, a distal end of the pusher member engages the tapered delivery tube inner surface so as to at least partially open the tube.
28. The system of Claim 25 additionally comprising a flexible collar disposed about the delivery tube segments distal of the proximal end of the delivery tube, wherein the collar is biased to hold the tube segments coupled together.
29. The system of Claim 28, wherein the collar is slidable over the delivery tube.
30. The system of Claim 25, wherein a distal portion of the pusher member is configured to contact a segment of the delivery tube at a location between about 2/3 and 3/4 of the distance from the proximal end to the distal end of the segment.
31. The system of Claim 24, wherein the pusher member has at least one protuberance, and the flexible locking member is disposed adjacent the protuberance so that when the locking member is subjected to longitudinal compression, the locking member expands transversely to engage the pusher member protuberance so that the pusher member is restrained from moving relative to the locking member.
32. The system of Claim 31, wherein the flexible locking member is configured to engage a proximal end of the delivery tube.
33. The system of Claim 32 additionally comprising a locking cap configured to selectively compress the flexible locking member between the cap and the proximal end of the delivery tube.
34. The system of Claim 33, wherein the locking cap is selectively engageable with the delivery tube.
CA2535452A 2003-08-14 2004-08-16 Vascular wound closure device Expired - Fee Related CA2535452C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA2801969A CA2801969C (en) 2003-08-14 2004-08-16 Vascular wound closure device

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US49542403P 2003-08-14 2003-08-14
US60/495,424 2003-08-14
US54715404P 2004-02-23 2004-02-23
US60/547,154 2004-02-23
PCT/US2004/026609 WO2005016152A2 (en) 2003-08-14 2004-08-16 Vascular wound closure device

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA2801969A Division CA2801969C (en) 2003-08-14 2004-08-16 Vascular wound closure device

Publications (2)

Publication Number Publication Date
CA2535452A1 true CA2535452A1 (en) 2005-02-24
CA2535452C CA2535452C (en) 2013-04-02

Family

ID=34198043

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2535452A Expired - Fee Related CA2535452C (en) 2003-08-14 2004-08-16 Vascular wound closure device

Country Status (8)

Country Link
US (2) US8012167B2 (en)
EP (2) EP2345371B1 (en)
JP (2) JP4722044B2 (en)
AT (1) ATE502580T1 (en)
AU (1) AU2004264981B2 (en)
CA (1) CA2535452C (en)
DE (1) DE602004031953D1 (en)
WO (1) WO2005016152A2 (en)

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US20050107826A1 (en) 2005-05-19
US8012167B2 (en) 2011-09-06
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CA2535452C (en) 2013-04-02
JP4722044B2 (en) 2011-07-13
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AU2004264981A1 (en) 2005-02-24
JP5127941B2 (en) 2013-01-23

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