CA2530052A1 - System and method for analyte measurement using dose sufficiency electrodes - Google Patents
System and method for analyte measurement using dose sufficiency electrodes Download PDFInfo
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- CA2530052A1 CA2530052A1 CA002530052A CA2530052A CA2530052A1 CA 2530052 A1 CA2530052 A1 CA 2530052A1 CA 002530052 A CA002530052 A CA 002530052A CA 2530052 A CA2530052 A CA 2530052A CA 2530052 A1 CA2530052 A1 CA 2530052A1
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- terminus
- test strip
- dose sufficiency
- biological fluid
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
- G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
- G01N27/3274—Corrective measures, e.g. error detection, compensation for temperature or hematocrit, calibration
Abstract
A method of determining dose sufficiency related parameters in a test strip for performing a measurement on a biological fluid comprising: a capillary fill chamber extending a length along the test strip from an intake opening to a terminus, a reagent disposed in the capillary fill chamber between the opening and the terminus, the reagent defining a measurement zone, and at least two dose sufficiency electrodes defining a gap there between and in operative with the capillary fill, chamber, the electrodes located between t he measurement zone and the terminus; applying the biological fluid to the opening, whereby the fluid flows from the opening towards the terminus; applying an AC test signal to a first one of the electrodes; determining the presence or absence of a response above a predetermined threshold at the second one of the electrodes, the response indicating that the fluid has occupied substantially all of the measurement zone.
Claims (65)
1. A method of determining dose sufficiency in a test strip for performing a measurement on a biological fluid comprising:
providing a biological fluid test strip, comprising:
a capillary fill chamber extending a length along the test strip from an intake opening to a terminus, a reagent disposed in the capillary fill chamber between the opening and the terminus, the reagent defining a measurement zone, and at least two dose sufficiency electrodes defining a gap therebetween and in operative communication with the capillary fill chamber, the electrodes located between the measurement zone and the terminus;
applying the biological fluid to the opening, whereby the fluid flows from the opening toward the terminus, the flow including a flow front selected from one of a concave, a convex and a substantially flat flow front;
applying a test signal to a first one of the electrodes;
determining the presence or absence of a response above a predetermined threshold at the second one of the electrodes, the response indicating that the fluid has occupied substantially all of the measurement zone regardless of whether the flow front is concave, convex or substantially flat.
providing a biological fluid test strip, comprising:
a capillary fill chamber extending a length along the test strip from an intake opening to a terminus, a reagent disposed in the capillary fill chamber between the opening and the terminus, the reagent defining a measurement zone, and at least two dose sufficiency electrodes defining a gap therebetween and in operative communication with the capillary fill chamber, the electrodes located between the measurement zone and the terminus;
applying the biological fluid to the opening, whereby the fluid flows from the opening toward the terminus, the flow including a flow front selected from one of a concave, a convex and a substantially flat flow front;
applying a test signal to a first one of the electrodes;
determining the presence or absence of a response above a predetermined threshold at the second one of the electrodes, the response indicating that the fluid has occupied substantially all of the measurement zone regardless of whether the flow front is concave, convex or substantially flat.
2. The method of claim 1, wherein the test signal is an AC signal.
3. The method of claim 1, wherein the response comprises magnitude and phase angle information.
4. The method of claim 1, wherein the response comprises an admittance value.
5. A method of determining dose sufficiency in a test strip for performing a measurement on a biological fluid comprising:
providing a biological fluid test strip, comprising:
a fluid flow intake opening, a fluid flow terminus, a reagent disposed on the test strip between the opening and the terminus, the reagent defining a measurement zone, and at least two dose sufficiency electrodes defining a gap therebetween and located between the measurement zone and the terminus;
applying the biological fluid to the opening, whereby the fluid flows from the opening toward the terminus, the flow including a flow front selected from one of a concave, a convex and a substantially flat flow front;
applying a test signal to a first one of the electrodes;
determining the presence or absence of a response above a predetermined threshold at the second one of the electrodes, the response indicating that the fluid has occupied substantially all of the measurement zone regardless of whether the flow front is concave, convex or substantially flat.
providing a biological fluid test strip, comprising:
a fluid flow intake opening, a fluid flow terminus, a reagent disposed on the test strip between the opening and the terminus, the reagent defining a measurement zone, and at least two dose sufficiency electrodes defining a gap therebetween and located between the measurement zone and the terminus;
applying the biological fluid to the opening, whereby the fluid flows from the opening toward the terminus, the flow including a flow front selected from one of a concave, a convex and a substantially flat flow front;
applying a test signal to a first one of the electrodes;
determining the presence or absence of a response above a predetermined threshold at the second one of the electrodes, the response indicating that the fluid has occupied substantially all of the measurement zone regardless of whether the flow front is concave, convex or substantially flat.
6. The method of claim 5, wherein the test signal is an AC signal.
7. The method of claim 5, wherein the response comprises magnitude and phase angle information.
8. The method of claim 5, wherein the response comprises an admittance value.
9. The method of claim 5, further comprising:
a capillary fill chamber extending a length along the test strip from the opening to the terminus; and wherein the reagent is disposed in the capillary fill chamber.
a capillary fill chamber extending a length along the test strip from the opening to the terminus; and wherein the reagent is disposed in the capillary fill chamber.
10. A method of determining a dose sufficiency in a test strip for performing a measurement on a biological fluid, comprising:
providing a biological fluid test strip comprising:
a capillary fill chamber extending a length along the test strip, at least two measurement electrodes in operative communication with the chamber, and at least two dose sufficiency electrodes in operative communication with the chamber;
applying the biological fluid to the test strip;
applying a dose sufficiency test signal having an AC component to one of the dose sufficiency electrodes; and measuring a response to the dose sufficiency test signal at the other of the dose sufficiency electrodes.
providing a biological fluid test strip comprising:
a capillary fill chamber extending a length along the test strip, at least two measurement electrodes in operative communication with the chamber, and at least two dose sufficiency electrodes in operative communication with the chamber;
applying the biological fluid to the test strip;
applying a dose sufficiency test signal having an AC component to one of the dose sufficiency electrodes; and measuring a response to the dose sufficiency test signal at the other of the dose sufficiency electrodes.
11. The method of claim 10, wherein the test signal is an AC signal.
12. The method of claim 10, wherein the response comprises magnitude and phase angle information.
13. The method of claim 10, wherein the response comprises an admittance value.
14. The method of claim 10 wherein the applying a dose sufficiency test signal results in the dose sufficiency electrodes exhibiting an edge effect.
15. The method of claim 10 wherein the AC component has a frequency of about kHz.
16. A method of determining a fill sufficiency in test strip for performing a measurement on a biological fluid comprising:
providing a biological fluid test strip including a capillary fill chamber extending a length along the test strip from an intake opening to a terminus, a measurement zone in the chamber positioned intermediate the opening and the terminus, and at least two dose sufficiency electrodes in operative communication with the chamber the electrodes positioned intermediate the measurement zone and the terminus;
introducing the biological fluid to the opening effective to cause the fluid to flow toward the terminus whereby the chamber is filled;
applying a test signal having an AC component to one of the dose sufficiency electrodes; and detecting a response or an absence of the response to the test signal at the other of the dose sufficiency electrodes effective to indicate the fill sufficiency of the biological fluid.
providing a biological fluid test strip including a capillary fill chamber extending a length along the test strip from an intake opening to a terminus, a measurement zone in the chamber positioned intermediate the opening and the terminus, and at least two dose sufficiency electrodes in operative communication with the chamber the electrodes positioned intermediate the measurement zone and the terminus;
introducing the biological fluid to the opening effective to cause the fluid to flow toward the terminus whereby the chamber is filled;
applying a test signal having an AC component to one of the dose sufficiency electrodes; and detecting a response or an absence of the response to the test signal at the other of the dose sufficiency electrodes effective to indicate the fill sufficiency of the biological fluid.
17. The method of claim 16, wherein the test signal is an AC signal.
18. The method of claim 16, wherein the response comprises magnitude and phase angle information.
19. The method of claim 16, wherein the response comprises an admittance value.
20. A method of determining a dose sufficiency in a test strip for performing a measurement on a biological fluid, comprising:
providing a biological fluid test strip comprising:
a fluid flow intake opening;
a fluid flow terminus;
a reagent disposed on the test strip between the opening and the terminus, the reagent defining a measurement zone; and at least two dose sufficiency electrodes defining a gap therebetween and located between the measurement zone and the terminus;
applying the biological fluid to the test strip;
applying a dose sufficiency test signal having an AC component to one of the dose sufficiency electrodes; and measuring a response to the dose sufficiency test signal at the other of the dose sufficiency electrodes.
providing a biological fluid test strip comprising:
a fluid flow intake opening;
a fluid flow terminus;
a reagent disposed on the test strip between the opening and the terminus, the reagent defining a measurement zone; and at least two dose sufficiency electrodes defining a gap therebetween and located between the measurement zone and the terminus;
applying the biological fluid to the test strip;
applying a dose sufficiency test signal having an AC component to one of the dose sufficiency electrodes; and measuring a response to the dose sufficiency test signal at the other of the dose sufficiency electrodes.
21. The method of claim 20, further comprising:
a capillary fill chamber extending a length along the test strip from the opening to the terminus; and wherein the reagent is disposed in the capillary fill chamber.
a capillary fill chamber extending a length along the test strip from the opening to the terminus; and wherein the reagent is disposed in the capillary fill chamber.
22. The method of claim 20, wherein the test signal is an AC signal.
23. The method of claim 20, wherein the response comprises magnitude and phase angle information.
24. The method of claim 20, wherein the response comprises an admittance value.
25. The method of claim 20 wherein the applying a dose sufficiency test signal results in the dose sufficiency electrodes exhibiting an edge effect.
26. The method of claim 20 wherein the AC component has a frequency of about kHz.
27. A method of determining a fill sufficiency in test strip for performing a measurement on a biological fluid comprising:
providing a biological fluid test strip, comprising:
a fluid flow intake opening;
a fluid flow terminus;
a measurement zone positioned intermediate the opening and the terminus, and at least two dose sufficiency electrodes positioned intermediate the measurement zone and the terminus;
introducing the biological fluid to the opening effective to cause the fluid to flow toward the terminus;
applying a test signal having an AC component to one of the dose sufficiency electrodes; and detecting a response or an absence of the response to the test signal at the other of the dose sufficiency electrodes effective to indicate a volume sufficiency of the biological fluid.
providing a biological fluid test strip, comprising:
a fluid flow intake opening;
a fluid flow terminus;
a measurement zone positioned intermediate the opening and the terminus, and at least two dose sufficiency electrodes positioned intermediate the measurement zone and the terminus;
introducing the biological fluid to the opening effective to cause the fluid to flow toward the terminus;
applying a test signal having an AC component to one of the dose sufficiency electrodes; and detecting a response or an absence of the response to the test signal at the other of the dose sufficiency electrodes effective to indicate a volume sufficiency of the biological fluid.
28. The method of claim 27, further comprising:
a capillary fill chamber extending a length along the test strip from the opening to the terminus.
a capillary fill chamber extending a length along the test strip from the opening to the terminus.
29. The method of claim 27, wherein the test signal is an AC signal.
30. The method of claim 27, wherein the response comprises magnitude and phase angle information.
31. The method of claim 27, wherein the response comprises an admittance value.
32. A method of determining dosage fill level in a test strip for performing a measurement on a biological fluid comprising:
providing a biological fluid test strip including a capillary fill chamber extending a length along the test strip from an opening to a terminus, and at least two dose sufficiency electrodes in operative communication with the chamber the dose sufficiency electrodes positioned to define a gap between one another;
dosing the test strip with a biological fluid effective to cause the biological fluid to begin to fill the chamber;
applying a test signal having an AC component to one of the dose sufficiency electrodes;
measuring a response to the signal at the other of the dose sufficiency electrodes;
determining the dosage fill level based upon the response.
providing a biological fluid test strip including a capillary fill chamber extending a length along the test strip from an opening to a terminus, and at least two dose sufficiency electrodes in operative communication with the chamber the dose sufficiency electrodes positioned to define a gap between one another;
dosing the test strip with a biological fluid effective to cause the biological fluid to begin to fill the chamber;
applying a test signal having an AC component to one of the dose sufficiency electrodes;
measuring a response to the signal at the other of the dose sufficiency electrodes;
determining the dosage fill level based upon the response.
33. The method of claim 32, wherein the test signal is an AC signal.
34. The method of claim 32, wherein the response comprises magnitude and phase angle information.
35. The method of claim 32, wherein the response comprises an admittance value.
36. The method of claim 32, wherein the response varies in correlation with the degree to which the biological fluid bridges the gap.
37. A method of determining a fill level of a biological fluid in a test strip for performing a measurement on the fluid comprising:
providing a test strip including a capillary fill chamber extending a length along the test strip from an opening to a terminus, and at least two dose sufficiency electrodes in operative communication with the chamber the dose sufficiency electrodes positioned to define a gap between one another;
introducing the biological fluid to the opening effective to cause the fluid to flow toward the terminus whereby the chamber is filled;
applying a test signal having an AC component to one of the dose sufficiency electrodes; and measuring a response to the test signal at the other of the dose sufficiency electrodes;
determining the fill level of the biological fluid based upon the response wherein the response varies in relation to the fill level.
providing a test strip including a capillary fill chamber extending a length along the test strip from an opening to a terminus, and at least two dose sufficiency electrodes in operative communication with the chamber the dose sufficiency electrodes positioned to define a gap between one another;
introducing the biological fluid to the opening effective to cause the fluid to flow toward the terminus whereby the chamber is filled;
applying a test signal having an AC component to one of the dose sufficiency electrodes; and measuring a response to the test signal at the other of the dose sufficiency electrodes;
determining the fill level of the biological fluid based upon the response wherein the response varies in relation to the fill level.
38. The method of claim 37, wherein the test signal is an AC signal.
39. The method of claim 37, wherein the response comprises magnitude and phase angle information.
40. The method of claim 37, wherein the response comprises an admittance value.
41. A method of determining dosage fill level in a test strip for performing a measurement on a biological fluid comprising:
providing a biological fluid test strip, comprising:
a capillary fill chamber extending a length along the test strip from an opening to a terminus, and at least two pairs of dose sufficiency electrodes in operative communication with the chamber, each of the pairs of dose sufficiency electrodes positioned to define a respective gap between one another;
dosing the test strip with a biological fluid effective to cause the biological fluid to begin to fill the chamber;
applying a test signal to one electrode of each of the dose sufficiency electrode pairs;
measuring a respective response to the test signal at the respective other electrode of each of the dose sufficiency electrode pairs;
determining the dosage fill level based upon the responses.
providing a biological fluid test strip, comprising:
a capillary fill chamber extending a length along the test strip from an opening to a terminus, and at least two pairs of dose sufficiency electrodes in operative communication with the chamber, each of the pairs of dose sufficiency electrodes positioned to define a respective gap between one another;
dosing the test strip with a biological fluid effective to cause the biological fluid to begin to fill the chamber;
applying a test signal to one electrode of each of the dose sufficiency electrode pairs;
measuring a respective response to the test signal at the respective other electrode of each of the dose sufficiency electrode pairs;
determining the dosage fill level based upon the responses.
42. The method of claim 41, wherein the test signal is an AC signal.
43. The method of claim 41, wherein the response comprises magnitude and phase angle information.
44. The method of claim 41, wherein the response comprises an admittance value.
45. A method of determining a fill level of a biological fluid in a test strip for performing a measurement on the fluid comprising:
providing a test strip, comprising:
a fluid flow intake opening;
a fluid flow terminus;
a reagent disposed on the test strip between the opening to the terminus; and at least two pairs of dose sufficiency electrodes positioned between the reagent and the terminus, each of the pairs of dose sufficiency electrodes defining a respective gap between one another;
introducing the biological fluid to the opening effective to cause the fluid to flow toward the terminus;
applying a test signal to one electrode of each of the dose sufficiency electrode pairs; and measuring a respective response to the test signal at the respective other electrode of each of the dose sufficiency electrode pairs;
determining the fill level of the biological fluid based upon the responses.
providing a test strip, comprising:
a fluid flow intake opening;
a fluid flow terminus;
a reagent disposed on the test strip between the opening to the terminus; and at least two pairs of dose sufficiency electrodes positioned between the reagent and the terminus, each of the pairs of dose sufficiency electrodes defining a respective gap between one another;
introducing the biological fluid to the opening effective to cause the fluid to flow toward the terminus;
applying a test signal to one electrode of each of the dose sufficiency electrode pairs; and measuring a respective response to the test signal at the respective other electrode of each of the dose sufficiency electrode pairs;
determining the fill level of the biological fluid based upon the responses.
46. The method of claim 45, wherein the test signal is an AC signal.
47. The method of claim 45, wherein the response comprises magnitude and phase angle information.
48. The method of claim 45, wherein the response comprises an admittance value.
49. A method of determining dosage fill rate in a biological fluid test strip comprising:
providing a biological fluid test strip, comprising:
a capillary fill chamber extending a length along the test strip from an opening to a terminus, and at least two dose sufficiency electrodes in operative communication with the chamber, the dose sufficiency electrodes positioned to define a gap between one another;
dosing the test strip with a biological fluid effective to cause the biological fluid to begin to fill the chamber;
applying a test signal having an AC component to one of the dose sufficiency electrodes;
measuring a first response to the test signal at the other of the dose sufficiency electrodes at a first time;
measuring a second response to the test signal at the other of the dose sufficiency electrodes at a second time; and determining a rate at which the biological fluid fills the chamber based at least in part upon the first response and the second response.
providing a biological fluid test strip, comprising:
a capillary fill chamber extending a length along the test strip from an opening to a terminus, and at least two dose sufficiency electrodes in operative communication with the chamber, the dose sufficiency electrodes positioned to define a gap between one another;
dosing the test strip with a biological fluid effective to cause the biological fluid to begin to fill the chamber;
applying a test signal having an AC component to one of the dose sufficiency electrodes;
measuring a first response to the test signal at the other of the dose sufficiency electrodes at a first time;
measuring a second response to the test signal at the other of the dose sufficiency electrodes at a second time; and determining a rate at which the biological fluid fills the chamber based at least in part upon the first response and the second response.
50. The method of claim 49, wherein the test signal is an AC signal.
51. The method of claim 49, wherein the response comprises magnitude and phase angle information.
52. The method of claim 49, wherein the response comprises an admittance value.
53. The method of claim 49 further comprising recording the first response and the second response.
54. A method of determining dosage fill rate in a biological fluid test strip comprising:
providing a biological fluid test strip, comprising:
a fluid flow intake opening;
a fluid flow terminus;
a measurement zone positioned between the opening and the terminus, and at least two dose sufficiency electrodes positioned between the measurement zone and the terminus, the dose sufficiency electrodes positioned to define a gap between one another;
dosing the test strip with a biological fluid effective to cause the biological fluid to begin to flow from the opening toward the terminus;
applying a test signal having an AC component to one of the dose sufficiency electrodes;
measuring a first response to the test signal at the other of the dose sufficiency electrodes at a first time;
measuring a second response to the test signal at the other of the dose sufficiency electrodes at a second time; and determining a rate at which the biological fluid fills the chamber based at least in part upon the first response and the second response.
providing a biological fluid test strip, comprising:
a fluid flow intake opening;
a fluid flow terminus;
a measurement zone positioned between the opening and the terminus, and at least two dose sufficiency electrodes positioned between the measurement zone and the terminus, the dose sufficiency electrodes positioned to define a gap between one another;
dosing the test strip with a biological fluid effective to cause the biological fluid to begin to flow from the opening toward the terminus;
applying a test signal having an AC component to one of the dose sufficiency electrodes;
measuring a first response to the test signal at the other of the dose sufficiency electrodes at a first time;
measuring a second response to the test signal at the other of the dose sufficiency electrodes at a second time; and determining a rate at which the biological fluid fills the chamber based at least in part upon the first response and the second response.
55. The method of claim 54, further comprising:
a capillary fill chamber extending a length along the test strip from the opening to the terminus.
a capillary fill chamber extending a length along the test strip from the opening to the terminus.
56. The method of claim 55, wherein the test signal is an AC signal.
57. The method of claim 55, wherein the response comprises magnitude and phase angle information.
58. The method of claim 55, wherein the response comprises an admittance value.
59. The method of claim 55 further comprising recording the first response and the second response.
60. A test strip for performing a measurement on a biological fluid comprising:
a capillary fill chamber extending a length along the test strip from an opening to a terminus;
at least two measurement electrodes in operative communication with the chamber; and at least two dose sufficiency electrodes in operative communication with the chamber;
wherein the dose sufficiency electrodes have first edges substantially parallel to the length of the capillary chamber and second edges substantially perpendicular to the length of the capillary fill chamber with the first edges being of greater length than the second edges.
a capillary fill chamber extending a length along the test strip from an opening to a terminus;
at least two measurement electrodes in operative communication with the chamber; and at least two dose sufficiency electrodes in operative communication with the chamber;
wherein the dose sufficiency electrodes have first edges substantially parallel to the length of the capillary chamber and second edges substantially perpendicular to the length of the capillary fill chamber with the first edges being of greater length than the second edges.
61. A test strip for performing a measurement on a biological fluid, comprising:
a capillary fill chamber extending a length along the test strip from an opening to a terminus;
a measurement zone in the chamber positioned intermediate the opening and the terminus, and at least two dose sufficiency electrodes in operative communication with the chamber the electrodes positioned intermediate the measurement zone and the terminus;
wherein the dose sufficiency electrodes have a first axis substantially parallel to the length of the capillary chamber and a second axis substantially perpendicular to the length of the capillary fill chamber with the first axis being of greater length than the second axis.
a capillary fill chamber extending a length along the test strip from an opening to a terminus;
a measurement zone in the chamber positioned intermediate the opening and the terminus, and at least two dose sufficiency electrodes in operative communication with the chamber the electrodes positioned intermediate the measurement zone and the terminus;
wherein the dose sufficiency electrodes have a first axis substantially parallel to the length of the capillary chamber and a second axis substantially perpendicular to the length of the capillary fill chamber with the first axis being of greater length than the second axis.
62. A test strip for performing a measurement on a biological fluid comprising:
a fluid flow path extending a length along the test strip from an opening to a terminus;
at least two measurement electrodes in operative communication with the fluid flow path; and at least two dose sufficiency electrodes in operative communication with the fluid flow path;
wherein the dose sufficiency electrodes have first edges substantially parallel to the length of the fluid flow path and second edges substantially perpendicular to the length of the fluid flow path with the first edges being of greater length than the second edges.
a fluid flow path extending a length along the test strip from an opening to a terminus;
at least two measurement electrodes in operative communication with the fluid flow path; and at least two dose sufficiency electrodes in operative communication with the fluid flow path;
wherein the dose sufficiency electrodes have first edges substantially parallel to the length of the fluid flow path and second edges substantially perpendicular to the length of the fluid flow path with the first edges being of greater length than the second edges.
63. The method of claim 62, further comprising:
a capillary fill chamber extending a length along the test strip from the opening to the terminus.
a capillary fill chamber extending a length along the test strip from the opening to the terminus.
64. A test strip for performing a measurement on a biological fluid, comprising:
a fluid flow path extending a length along the test strip from an opening to a terminus;
a measurement zone in the chamber positioned intermediate the opening and the terminus, and at least two dose sufficiency electrodes in operative communication with the fluid flow path, the electrodes positioned intermediate the measurement zone and the terminus;
wherein the dose sufficiency electrodes have a first axis substantially parallel to the length of the fluid flow path and a second axis substantially perpendicular to the length of the fluid flow path with the first axis being of greater length than the second axis.
a fluid flow path extending a length along the test strip from an opening to a terminus;
a measurement zone in the chamber positioned intermediate the opening and the terminus, and at least two dose sufficiency electrodes in operative communication with the fluid flow path, the electrodes positioned intermediate the measurement zone and the terminus;
wherein the dose sufficiency electrodes have a first axis substantially parallel to the length of the fluid flow path and a second axis substantially perpendicular to the length of the fluid flow path with the first axis being of greater length than the second axis.
65. The method of claim 64, further comprising:
a capillary fill chamber extending a length along the test strip from the opening to the terminus.
a capillary fill chamber extending a length along the test strip from the opening to the terminus.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CA2714309A CA2714309C (en) | 2003-06-20 | 2004-06-18 | System and method for analyte measurement using dose sufficiency electrodes |
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US48029803P | 2003-06-20 | 2003-06-20 | |
US60/480,298 | 2003-06-20 | ||
US10/687,958 | 2003-10-17 | ||
US10/687,958 US7452457B2 (en) | 2003-06-20 | 2003-10-17 | System and method for analyte measurement using dose sufficiency electrodes |
PCT/US2004/019721 WO2005008231A1 (en) | 2003-06-20 | 2004-06-18 | System and method for analyte measurement of biological fluids using dose sufficiency electrodes |
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CA2714309A Division CA2714309C (en) | 2003-06-20 | 2004-06-18 | System and method for analyte measurement using dose sufficiency electrodes |
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CA2530052A1 true CA2530052A1 (en) | 2005-01-27 |
CA2530052C CA2530052C (en) | 2010-11-30 |
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CA2530052A Active CA2530052C (en) | 2003-06-20 | 2004-06-18 | System and method for analyte measurement using dose sufficiency electrodes |
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Families Citing this family (136)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6036924A (en) | 1997-12-04 | 2000-03-14 | Hewlett-Packard Company | Cassette of lancet cartridges for sampling blood |
US6391005B1 (en) | 1998-03-30 | 2002-05-21 | Agilent Technologies, Inc. | Apparatus and method for penetration with shaft having a sensor for sensing penetration depth |
US8641644B2 (en) | 2000-11-21 | 2014-02-04 | Sanofi-Aventis Deutschland Gmbh | Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means |
US9795747B2 (en) | 2010-06-02 | 2017-10-24 | Sanofi-Aventis Deutschland Gmbh | Methods and apparatus for lancet actuation |
US7025774B2 (en) | 2001-06-12 | 2006-04-11 | Pelikan Technologies, Inc. | Tissue penetration device |
DE60238119D1 (en) | 2001-06-12 | 2010-12-09 | Pelikan Technologies Inc | ELECTRIC ACTUATOR ELEMENT FOR A LANZETTE |
US7316700B2 (en) | 2001-06-12 | 2008-01-08 | Pelikan Technologies, Inc. | Self optimizing lancing device with adaptation means to temporal variations in cutaneous properties |
US7981056B2 (en) | 2002-04-19 | 2011-07-19 | Pelikan Technologies, Inc. | Methods and apparatus for lancet actuation |
US9226699B2 (en) | 2002-04-19 | 2016-01-05 | Sanofi-Aventis Deutschland Gmbh | Body fluid sampling module with a continuous compression tissue interface surface |
US7699791B2 (en) | 2001-06-12 | 2010-04-20 | Pelikan Technologies, Inc. | Method and apparatus for improving success rate of blood yield from a fingerstick |
US9427532B2 (en) | 2001-06-12 | 2016-08-30 | Sanofi-Aventis Deutschland Gmbh | Tissue penetration device |
US8337419B2 (en) | 2002-04-19 | 2012-12-25 | Sanofi-Aventis Deutschland Gmbh | Tissue penetration device |
US7749174B2 (en) | 2001-06-12 | 2010-07-06 | Pelikan Technologies, Inc. | Method and apparatus for lancet launching device intergrated onto a blood-sampling cartridge |
EP1404232B1 (en) | 2001-06-12 | 2009-12-02 | Pelikan Technologies Inc. | Blood sampling apparatus and method |
US7717863B2 (en) | 2002-04-19 | 2010-05-18 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US9795334B2 (en) | 2002-04-19 | 2017-10-24 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for penetrating tissue |
US8702624B2 (en) | 2006-09-29 | 2014-04-22 | Sanofi-Aventis Deutschland Gmbh | Analyte measurement device with a single shot actuator |
US7297122B2 (en) | 2002-04-19 | 2007-11-20 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US7291117B2 (en) | 2002-04-19 | 2007-11-06 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US7229458B2 (en) | 2002-04-19 | 2007-06-12 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US7976476B2 (en) | 2002-04-19 | 2011-07-12 | Pelikan Technologies, Inc. | Device and method for variable speed lancet |
US7331931B2 (en) | 2002-04-19 | 2008-02-19 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US8221334B2 (en) | 2002-04-19 | 2012-07-17 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for penetrating tissue |
US7371247B2 (en) | 2002-04-19 | 2008-05-13 | Pelikan Technologies, Inc | Method and apparatus for penetrating tissue |
US8360992B2 (en) | 2002-04-19 | 2013-01-29 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for penetrating tissue |
US8579831B2 (en) | 2002-04-19 | 2013-11-12 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for penetrating tissue |
US7547287B2 (en) | 2002-04-19 | 2009-06-16 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US8267870B2 (en) | 2002-04-19 | 2012-09-18 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for body fluid sampling with hybrid actuation |
US9248267B2 (en) | 2002-04-19 | 2016-02-02 | Sanofi-Aventis Deustchland Gmbh | Tissue penetration device |
US7892183B2 (en) | 2002-04-19 | 2011-02-22 | Pelikan Technologies, Inc. | Method and apparatus for body fluid sampling and analyte sensing |
US7909778B2 (en) | 2002-04-19 | 2011-03-22 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US7713214B2 (en) | 2002-04-19 | 2010-05-11 | Pelikan Technologies, Inc. | Method and apparatus for a multi-use body fluid sampling device with optical analyte sensing |
US8784335B2 (en) | 2002-04-19 | 2014-07-22 | Sanofi-Aventis Deutschland Gmbh | Body fluid sampling device with a capacitive sensor |
US7491178B2 (en) | 2002-04-19 | 2009-02-17 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US9314194B2 (en) | 2002-04-19 | 2016-04-19 | Sanofi-Aventis Deutschland Gmbh | Tissue penetration device |
US7648468B2 (en) | 2002-04-19 | 2010-01-19 | Pelikon Technologies, Inc. | Method and apparatus for penetrating tissue |
US7901362B2 (en) | 2002-04-19 | 2011-03-08 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US7175642B2 (en) | 2002-04-19 | 2007-02-13 | Pelikan Technologies, Inc. | Methods and apparatus for lancet actuation |
US8372016B2 (en) | 2002-04-19 | 2013-02-12 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for body fluid sampling and analyte sensing |
US7674232B2 (en) | 2002-04-19 | 2010-03-09 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US7232451B2 (en) | 2002-04-19 | 2007-06-19 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US8574895B2 (en) | 2002-12-30 | 2013-11-05 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus using optical techniques to measure analyte levels |
US8262614B2 (en) | 2003-05-30 | 2012-09-11 | Pelikan Technologies, Inc. | Method and apparatus for fluid injection |
US7850621B2 (en) | 2003-06-06 | 2010-12-14 | Pelikan Technologies, Inc. | Method and apparatus for body fluid sampling and analyte sensing |
WO2006001797A1 (en) | 2004-06-14 | 2006-01-05 | Pelikan Technologies, Inc. | Low pain penetrating |
KR100785670B1 (en) | 2003-06-20 | 2007-12-14 | 에프. 호프만-라 로슈 아게 | Method and reagent for producing narrow, homogenous reagent strips |
US7452457B2 (en) * | 2003-06-20 | 2008-11-18 | Roche Diagnostics Operations, Inc. | System and method for analyte measurement using dose sufficiency electrodes |
US8148164B2 (en) | 2003-06-20 | 2012-04-03 | Roche Diagnostics Operations, Inc. | System and method for determining the concentration of an analyte in a sample fluid |
WO2004113910A1 (en) * | 2003-06-20 | 2004-12-29 | Roche Diagnostics Gmbh | Devices and methods relating to electrochemical biosensors |
US20070264721A1 (en) * | 2003-10-17 | 2007-11-15 | Buck Harvey B | System and method for analyte measurement using a nonlinear sample response |
WO2005033659A2 (en) | 2003-09-29 | 2005-04-14 | Pelikan Technologies, Inc. | Method and apparatus for an improved sample capture device |
EP1680014A4 (en) | 2003-10-14 | 2009-01-21 | Pelikan Technologies Inc | Method and apparatus for a variable user interface |
US8007656B2 (en) | 2003-10-24 | 2011-08-30 | Bayer Healthcare Llc | Enzymatic electrochemical biosensor |
US8668656B2 (en) | 2003-12-31 | 2014-03-11 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for improving fluidic flow and sample capture |
US7822454B1 (en) | 2005-01-03 | 2010-10-26 | Pelikan Technologies, Inc. | Fluid sampling device with improved analyte detecting member configuration |
CA2553632A1 (en) | 2004-02-06 | 2005-08-25 | Bayer Healthcare Llc | Oxidizable species as an internal reference for biosensors and method of use |
WO2006011062A2 (en) | 2004-05-20 | 2006-02-02 | Albatros Technologies Gmbh & Co. Kg | Printable hydrogel for biosensors |
EP1765194A4 (en) | 2004-06-03 | 2010-09-29 | Pelikan Technologies Inc | Method and apparatus for a fluid sampling device |
US9775553B2 (en) | 2004-06-03 | 2017-10-03 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for a fluid sampling device |
US7556723B2 (en) * | 2004-06-18 | 2009-07-07 | Roche Diagnostics Operations, Inc. | Electrode design for biosensor |
WO2006000505A2 (en) * | 2004-06-23 | 2006-01-05 | Tesa Ag | Medical biosensor by means of which biological liquids are analyzed |
US8652831B2 (en) | 2004-12-30 | 2014-02-18 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for analyte measurement test time |
BRPI0613592A2 (en) | 2005-07-20 | 2011-01-18 | Bayer Healthcare Llc | port-connected amperometry |
EP3483598A1 (en) | 2005-09-30 | 2019-05-15 | Ascensia Diabetes Care Holdings AG | Gated voltammetry |
DK1949101T3 (en) * | 2005-11-14 | 2013-06-10 | Bayer Healthcare Llc | Assay Sensor Reagent with Cellulose Polymers |
EP1813937A1 (en) * | 2006-01-25 | 2007-08-01 | Roche Diagnostics GmbH | Electrochemical biosensor analysis system |
RU2455925C2 (en) * | 2006-02-27 | 2012-07-20 | БАЙЕР ХЕЛТКЭА ЭлЭлСи | Determination of investigated substance with correction to temperature for systems of biosensors |
US7887682B2 (en) | 2006-03-29 | 2011-02-15 | Abbott Diabetes Care Inc. | Analyte sensors and methods of use |
US8529751B2 (en) | 2006-03-31 | 2013-09-10 | Lifescan, Inc. | Systems and methods for discriminating control solution from a physiological sample |
US8398443B2 (en) * | 2006-04-21 | 2013-03-19 | Roche Diagnostics Operations, Inc. | Biological testing system and connector therefor |
US7966859B2 (en) * | 2006-05-03 | 2011-06-28 | Bayer Healthcare Llc | Underfill detection system for a biosensor |
US7312042B1 (en) | 2006-10-24 | 2007-12-25 | Abbott Diabetes Care, Inc. | Embossed cell analyte sensor and methods of manufacture |
MX347099B (en) | 2006-10-24 | 2017-04-12 | Ascensia Diabetes Care Holdings Ag | Transient decay amperometry. |
US20100066356A1 (en) * | 2006-12-15 | 2010-03-18 | Koninklijke Philips Electronics N.V. | Sensor device comprising means for determining the sample covered area of the sensitive surface |
US8409424B2 (en) * | 2006-12-19 | 2013-04-02 | Apex Biotechnology Corp. | Electrochemical test strip, electrochemical test system, and measurement method using the same |
EP2535830B1 (en) | 2007-05-30 | 2018-11-21 | Ascensia Diabetes Care Holdings AG | Method and system for managing health data |
JP4856009B2 (en) * | 2007-05-31 | 2012-01-18 | グンゼ株式会社 | Biosensor |
JP4856011B2 (en) * | 2007-06-05 | 2012-01-18 | グンゼ株式会社 | Biosensor |
US8778168B2 (en) | 2007-09-28 | 2014-07-15 | Lifescan, Inc. | Systems and methods of discriminating control solution from a physiological sample |
CN101842696A (en) * | 2007-10-31 | 2010-09-22 | 爱科来株式会社 | Analysis tool, analyzer, sample shortage detection method, and sample analysis method |
WO2009076302A1 (en) | 2007-12-10 | 2009-06-18 | Bayer Healthcare Llc | Control markers for auto-detection of control solution and methods of use |
WO2009108239A2 (en) * | 2007-12-10 | 2009-09-03 | Bayer Healthcare Llc | Slope-based compensation |
AU2015203087B2 (en) * | 2008-01-17 | 2017-03-16 | Lifescan, Inc. | System and method for measuring an analyte in a sample |
AU2013202716B2 (en) * | 2008-01-17 | 2014-09-11 | Lifescan, Inc. | System and method for measuring an analyte in a sample |
US8603768B2 (en) * | 2008-01-17 | 2013-12-10 | Lifescan, Inc. | System and method for measuring an analyte in a sample |
US8431011B2 (en) * | 2008-01-31 | 2013-04-30 | Abbott Diabetes Care Inc. | Method for automatically and rapidly distinguishing between control and sample solutions in a biosensor strip |
JP2009250806A (en) | 2008-04-07 | 2009-10-29 | Panasonic Corp | Biosensor system, sensor chip and measuring method of concentration of analyte in blood sample |
EP2265324B1 (en) | 2008-04-11 | 2015-01-28 | Sanofi-Aventis Deutschland GmbH | Integrated analyte measurement system |
AU2012201915C1 (en) * | 2008-06-09 | 2014-09-25 | Lifescan, Inc. | System and method for measuring an analyte in a sample |
US8551320B2 (en) * | 2008-06-09 | 2013-10-08 | Lifescan, Inc. | System and method for measuring an analyte in a sample |
CN102227636A (en) * | 2008-09-30 | 2011-10-26 | 梅纳伊医疗科技有限公司 | Sample measurement system |
US8649997B2 (en) * | 2008-10-03 | 2014-02-11 | Bayer Healthcare Llc | Systems and methods for predicting ambient temperature in a fluid analyte meter |
MX2011005864A (en) | 2008-12-08 | 2011-06-20 | Bayer Healthcare Llc | Biosensor system with signal adjustment. |
US9375169B2 (en) | 2009-01-30 | 2016-06-28 | Sanofi-Aventis Deutschland Gmbh | Cam drive for managing disposable penetrating member actions with a single motor and motor and control system |
WO2010151592A1 (en) * | 2009-06-23 | 2010-12-29 | Bayer Healthcare Llc | System and apparatus for determining temperatures in a fluid analyte system |
US20110048972A1 (en) * | 2009-08-31 | 2011-03-03 | Lifescan Scotland Limited | Multi-analyte test strip with shared counter/reference electrode and inline electrode configuration |
CA2776332C (en) * | 2009-11-10 | 2018-05-01 | Bayer Healthcare Llc | Underfill recognition system for a biosensor |
US8877034B2 (en) | 2009-12-30 | 2014-11-04 | Lifescan, Inc. | Systems, devices, and methods for measuring whole blood hematocrit based on initial fill velocity |
US8101065B2 (en) * | 2009-12-30 | 2012-01-24 | Lifescan, Inc. | Systems, devices, and methods for improving accuracy of biosensors using fill time |
US20110168575A1 (en) * | 2010-01-08 | 2011-07-14 | Roche Diaagnostics Operations, Inc. | Sample characterization based on ac measurement methods |
US20110208435A1 (en) * | 2010-02-25 | 2011-08-25 | Lifescan Scotland Ltd. | Capacitance detection in electrochemical assays |
MX2012010860A (en) * | 2010-03-22 | 2013-03-05 | Bayer Healthcare Llc | Residual compensation for a biosensor. |
GB201005359D0 (en) | 2010-03-30 | 2010-05-12 | Menai Medical Technologies Ltd | Sampling plate |
GB201005357D0 (en) | 2010-03-30 | 2010-05-12 | Menai Medical Technologies Ltd | Sampling plate |
US8123572B2 (en) | 2010-04-02 | 2012-02-28 | Tyco Electronics Corporation | Electrical components having a contact configured to engage a via of a circuit board |
US8965476B2 (en) | 2010-04-16 | 2015-02-24 | Sanofi-Aventis Deutschland Gmbh | Tissue penetration device |
WO2011156152A1 (en) * | 2010-06-07 | 2011-12-15 | Bayer Healthcare Llc | Slope-based compensation including secondary output signals |
RU2566382C2 (en) | 2010-06-07 | 2015-10-27 | БАЙЕР ХЕЛТКЭА ЭлЭлСи | Control system of insufficient filling for biosensor |
US20130092536A1 (en) | 2010-07-23 | 2013-04-18 | Roche Diagnostics Operations, Inc. | Zwitterion buffer containing compositions and uses in electroanalytical methods |
US8603323B2 (en) * | 2010-09-20 | 2013-12-10 | Lifescan, Inc. | Apparatus and process for improved measurements of a monitoring device |
US8932445B2 (en) | 2010-09-30 | 2015-01-13 | Cilag Gmbh International | Systems and methods for improved stability of electrochemical sensors |
US8617370B2 (en) | 2010-09-30 | 2013-12-31 | Cilag Gmbh International | Systems and methods of discriminating between a control sample and a test fluid using capacitance |
JP5728568B2 (en) * | 2011-02-23 | 2015-06-03 | パナソニックヘルスケアホールディングス株式会社 | Biological sample measuring device |
ES2663097T3 (en) | 2011-09-21 | 2018-04-11 | Ascensia Diabetes Care Holdings Ag | Biosensor with error compensation |
US9903830B2 (en) | 2011-12-29 | 2018-02-27 | Lifescan Scotland Limited | Accurate analyte measurements for electrochemical test strip based on sensed physical characteristic(s) of the sample containing the analyte |
GB2551943B (en) * | 2012-04-13 | 2018-08-01 | Smartcare Tech Limited | Improvements in and relating to sample measurement |
KR101466222B1 (en) * | 2012-06-01 | 2014-12-01 | 주식회사 아이센스 | Electrochemical biosensor with improved accuracy |
TWI513978B (en) * | 2012-06-08 | 2015-12-21 | Hmd Biomedical Inc | Test strip, detecting device and detection method |
AU2012385950B2 (en) * | 2012-07-27 | 2017-04-06 | Ascensia Diabetes Care Holdings Ag | System and method for detecting used and dried sensors |
CN105164523B (en) * | 2013-03-15 | 2017-09-12 | 豪夫迈·罗氏有限公司 | Scale the method for the data for constructing biology sensor algorithm and merge the unit and system of methods described |
WO2014140177A2 (en) | 2013-03-15 | 2014-09-18 | Roche Diagnostics Gmbh | Methods of detecting high antioxidant levels during electrochemical measurements and failsafing an analyte concentration therefrom as well as devices, apparatuses and systems incorporting the same |
EP2972268B1 (en) | 2013-03-15 | 2017-05-24 | Roche Diabetes Care GmbH | Methods of failsafing electrochemical measurements of an analyte as well as devices, apparatuses and systems incorporating the same |
WO2014140164A1 (en) | 2013-03-15 | 2014-09-18 | Roche Diagnostics Gmbh | Methods of using information from recovery pulses in electrochemical analyte measurements as well as devices, apparatuses and systems incorporating the same |
JP6521948B2 (en) * | 2013-06-10 | 2019-05-29 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | Method and system for detecting an analyte in body fluid |
TWI576583B (en) * | 2013-08-02 | 2017-04-01 | 達爾生技股份有限公司 | Determination methods for biochemical detection strips |
US9459231B2 (en) | 2013-08-29 | 2016-10-04 | Lifescan Scotland Limited | Method and system to determine erroneous measurement signals during a test measurement sequence |
US9243276B2 (en) | 2013-08-29 | 2016-01-26 | Lifescan Scotland Limited | Method and system to determine hematocrit-insensitive glucose values in a fluid sample |
JP5702457B2 (en) * | 2013-12-06 | 2015-04-15 | パナソニックヘルスケアホールディングス株式会社 | Biosensor system, sensor chip and method for measuring analyte concentration in blood sample |
WO2016073395A1 (en) | 2014-11-03 | 2016-05-12 | Roche Diabetes Care, Inc. | Electrode arrangements for electrochemical test elements and methods of use thereof |
TWI531790B (en) | 2014-11-10 | 2016-05-01 | 五鼎生物技術股份有限公司 | Electrochemical test strip, measurement system and method for determining sample content in the reactive region of the electrochemical test strip |
CN107209174B (en) * | 2014-11-25 | 2020-01-21 | 聚合物技术系统公司 | System and method for determining electrochemical hematocrit by alternating current impedance phase angle detection |
WO2016097079A1 (en) * | 2014-12-19 | 2016-06-23 | Roche Diagnostics Gmbh | Test element for electrochemically detecting at least one analyte |
CN109804240A (en) | 2016-10-05 | 2019-05-24 | 豪夫迈·罗氏有限公司 | Detection reagent and electrode arrangement and its application method for multiple analyte diagnostic test element |
CA3061348C (en) | 2017-06-08 | 2023-02-14 | F. Hoffmann-La Roche Ag | Electrode break detection |
USD936855S1 (en) * | 2018-02-09 | 2021-11-23 | Euroimmun Medizinische Labordiagnostika Ag | Device or instrument for medical diagnostics |
JP2023513053A (en) * | 2020-01-30 | 2023-03-30 | エムエックススリー・ダイアグノスティクス・インコーポレイテッド | Evaluation of biological fluid samples |
Family Cites Families (621)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US286735A (en) | 1883-10-16 | Heineicii eossleb | ||
US672094A (en) | 1900-08-27 | 1901-04-16 | George Cliffton | Feed-cooker. |
US2526651A (en) | 1945-08-02 | 1950-10-24 | Hydrocarbon Research Inc | Separating powdered catalysts from exothermically reactive gases |
GB787123A (en) | 1954-03-18 | 1957-12-04 | Rheinpreussen Ag | Apparatus for the catalytic gas reactions in liquid media |
US2883169A (en) | 1955-04-29 | 1959-04-21 | Mining Process & Patent Co | Aerating apparatus for flotation pulps |
US3526480A (en) | 1966-12-15 | 1970-09-01 | Xerox Corp | Automated chemical analyzer |
US3551295A (en) | 1967-11-29 | 1970-12-29 | Northrop Corp | Microbiological detection and identification system |
US3621381A (en) | 1968-10-16 | 1971-11-16 | Leeds & Northrup Co | Coulometric system having compensation for temperature induced viscosity changes |
BE754658A (en) * | 1969-08-12 | 1971-02-10 | Merck Patent Gmbh | INDICATOR SHEET, CONSISTING OF AN IMPREGNATED, ABSORBENT, SHEATHED HAIR MATERIAL |
US3644824A (en) | 1970-02-09 | 1972-02-22 | Atomic Energy Authority Uk | Polarograph apparatus |
US3661748A (en) | 1970-04-07 | 1972-05-09 | Instrumentation Labor Inc | Fault sensing instrumentation |
US3770607A (en) | 1970-04-07 | 1973-11-06 | Secretary | Glucose determination apparatus |
US3656543A (en) | 1970-05-25 | 1972-04-18 | Foster Wheeler Corp | Liquid metal heat exchanger |
US3919627A (en) | 1970-08-06 | 1975-11-11 | Gerald F Allen | Conductivity measuring method and apparatus utilizing coaxial electrode cells |
US3776832A (en) | 1970-11-10 | 1973-12-04 | Energetics Science | Electrochemical detection cell |
US3720093A (en) * | 1970-12-03 | 1973-03-13 | Us Navy | Carbon dioxide indicating meter |
US3718568A (en) * | 1971-05-21 | 1973-02-27 | Instrumentation Labor Inc | Electrochemical sensor instrumentation |
CH559912A5 (en) | 1971-09-09 | 1975-03-14 | Hoffmann La Roche | |
US3763422A (en) | 1971-10-21 | 1973-10-02 | Corning Glass Works | Method and apparatus for electrochemical analysis of small samples of blood |
US3870099A (en) * | 1972-05-19 | 1975-03-11 | Atomic Energy Commission | Seal assembly |
US3925183A (en) | 1972-06-16 | 1975-12-09 | Energetics Science | Gas detecting and quantitative measuring device |
US3902970A (en) | 1973-07-30 | 1975-09-02 | Leeds & Northrup Co | Flow-through amperometric measuring system and method |
CH585907A5 (en) * | 1973-08-06 | 1977-03-15 | Hoffmann La Roche | |
US3993947A (en) * | 1974-09-19 | 1976-11-23 | Drexelbrook Controls, Inc. | Admittance measuring system for monitoring the condition of materials |
US3937615A (en) * | 1974-12-17 | 1976-02-10 | Leeds & Northrup Company | Auto-ranging glucose measuring system |
FR2295419A1 (en) | 1974-12-21 | 1976-07-16 | Kyoto Daiichi Kagaku Kk | REFLECTANCE MEASURING DEVICE AND COMPOSITE TEST PAPER STRUCTURE SUBJECT TO SUCH MEASUREMENT |
US4052596A (en) | 1974-12-23 | 1977-10-04 | Hycel, Inc. | Automatic hematology analyzer |
US4060127A (en) | 1975-04-15 | 1977-11-29 | Nikolai Ivanovich Savin | Shell-and-tube heat exchanger |
US4008448A (en) * | 1975-10-03 | 1977-02-15 | Polaroid Corporation | Solenoid with selectively arrestible plunger movement |
US4230537A (en) | 1975-12-18 | 1980-10-28 | Monsanto Company | Discrete biochemical electrode system |
US4040908A (en) | 1976-03-12 | 1977-08-09 | Children's Hospital Medical Center | Polarographic analysis of cholesterol and other macromolecular substances |
US4065263A (en) | 1976-04-02 | 1977-12-27 | Woodbridge Iii Richard G | Analytical test strip apparatus |
US4053381A (en) | 1976-05-19 | 1977-10-11 | Eastman Kodak Company | Device for determining ionic activity of components of liquid drops |
US4123701A (en) | 1976-07-01 | 1978-10-31 | United States Surgical Corporation | Disposable sample card having a well with electrodes for testing a liquid sample |
US4092635A (en) | 1976-09-20 | 1978-05-30 | Baxter Travenol Laboratories, Inc. | Humidity sensor alarm unit |
US4127448A (en) | 1977-02-28 | 1978-11-28 | Schick Karl G | Amperometric-non-enzymatic method of determining sugars and other polyhydroxy compounds |
US4214203A (en) | 1977-06-17 | 1980-07-22 | Unisearch Limited | Location and effect of adsorbed chemicals on the dielectric substructure of membranes by ultra low frequency spectrometry |
JPS5912135B2 (en) | 1977-09-28 | 1984-03-21 | 松下電器産業株式会社 | enzyme electrode |
JPS5460996A (en) | 1977-10-22 | 1979-05-16 | Mitsubishi Chem Ind | Method of measuring amount of sugar |
US4214968A (en) | 1978-04-05 | 1980-07-29 | Eastman Kodak Company | Ion-selective electrode |
DE2817363C2 (en) | 1978-04-20 | 1984-01-26 | Siemens AG, 1000 Berlin und 8000 München | Method for determining the concentration of sugar and a suitable electrocatalytic sugar sensor |
DE2823485C2 (en) | 1978-05-30 | 1986-03-27 | Albert Prof. Dr. 3550 Marburg Huch | Trough electrode |
US4184936A (en) * | 1978-07-24 | 1980-01-22 | Eastman Kodak Company | Device for determining ionic activity |
CA1129498A (en) | 1978-10-25 | 1982-08-10 | Richard L. Columbus | Structural configuration and method for transport of a liquid drop through an ingress aperture |
US4233029A (en) | 1978-10-25 | 1980-11-11 | Eastman Kodak Company | Liquid transport device and method |
US4225410A (en) | 1978-12-04 | 1980-09-30 | Technicon Instruments Corporation | Integrated array of electrochemical sensors |
US4329642A (en) | 1979-03-09 | 1982-05-11 | Siliconix, Incorporated | Carrier and test socket for leadless integrated circuit |
US4273134A (en) | 1979-05-22 | 1981-06-16 | Biochem International Inc. | Fixation ring assembly and method of assembling a sensor head |
US4273639A (en) | 1979-06-20 | 1981-06-16 | Eastman Kodak Company | Capillary bridge in apparatus for determining ionic activity |
US4297569A (en) | 1979-06-28 | 1981-10-27 | Datakey, Inc. | Microelectronic memory key with receptacle and systems therefor |
US4265250A (en) | 1979-07-23 | 1981-05-05 | Battle Research And Development Associates | Electrode |
US4263343A (en) | 1979-08-13 | 1981-04-21 | Eastman Kodak Company | Reference elements for ion-selective membrane electrodes |
US4303887A (en) | 1979-10-29 | 1981-12-01 | United States Surgical Corporation | Electrical liquid conductivity measuring system |
US4301412A (en) | 1979-10-29 | 1981-11-17 | United States Surgical Corporation | Liquid conductivity measuring system and sample cards therefor |
US4628193A (en) | 1980-01-30 | 1986-12-09 | Blum Alvin S | Code reading operations supervisor |
US4323536A (en) | 1980-02-06 | 1982-04-06 | Eastman Kodak Company | Multi-analyte test device |
US4413407A (en) | 1980-03-10 | 1983-11-08 | Eastman Kodak Company | Method for forming an electrode-containing device with capillary transport between electrodes |
DE3029579C2 (en) | 1980-08-05 | 1985-12-12 | Boehringer Mannheim Gmbh, 6800 Mannheim | Method and means for separating plasma or serum from whole blood |
US4816224A (en) * | 1980-08-05 | 1989-03-28 | Boehringer Mannheim Gmbh | Device for separating plasma or serum from whole blood and analyzing the same |
US4407959A (en) | 1980-10-29 | 1983-10-04 | Fuji Electric Co., Ltd. | Blood sugar analyzing apparatus |
US4413628A (en) | 1980-11-19 | 1983-11-08 | Tamulis Walter G | pH Monitor electrode electrolyte cartridge |
US4420564A (en) | 1980-11-21 | 1983-12-13 | Fuji Electric Company, Ltd. | Blood sugar analyzer having fixed enzyme membrane sensor |
DE3047782A1 (en) * | 1980-12-18 | 1982-07-08 | Drägerwerk AG, 2400 Lübeck | CIRCUIT FOR THE CORRECTION OF THE SENSOR OUTPUT SIZE |
US4426451A (en) | 1981-01-28 | 1984-01-17 | Eastman Kodak Company | Multi-zoned reaction vessel having pressure-actuatable control means between zones |
US4436094A (en) * | 1981-03-09 | 1984-03-13 | Evreka, Inc. | Monitor for continuous in vivo measurement of glucose concentration |
US4407290A (en) | 1981-04-01 | 1983-10-04 | Biox Technology, Inc. | Blood constituent measuring device and method |
AT369254B (en) | 1981-05-07 | 1982-12-27 | Otto Dipl Ing Dr Tech Prohaska | MEDICAL PROBE |
US4440175A (en) | 1981-08-10 | 1984-04-03 | University Patents, Inc. | Membrane electrode for non-ionic species |
DE3133826A1 (en) | 1981-08-27 | 1983-03-10 | Boehringer Mannheim Gmbh, 6800 Mannheim | ANALYSIS TEST STRIP AND METHOD FOR THE PRODUCTION THEREOF |
DE3137174A1 (en) | 1981-09-18 | 1983-04-07 | Boehringer Mannheim Gmbh, 6800 Mannheim | DEVICE FOR THE OPTICAL DETECTION OF A CODING ON A DIAGNOSTIC TEST STRIP |
EP0078636B2 (en) | 1981-10-23 | 1997-04-02 | MediSense, Inc. | Sensor for components of a liquid mixture |
US4431004A (en) * | 1981-10-27 | 1984-02-14 | Bessman Samuel P | Implantable glucose sensor |
NZ199380A (en) * | 1981-12-23 | 1986-08-08 | J R Baker | Determination of serum glucose levels in blood samples |
DE3202067C2 (en) | 1982-01-23 | 1984-06-20 | Holger Dr. 5100 Aachen Kiesewetter | Device for determining the hematocrit value |
DE3228551A1 (en) | 1982-07-30 | 1984-02-02 | Siemens AG, 1000 Berlin und 8000 München | METHOD FOR DETERMINING SUGAR CONCENTRATION |
DE3228542A1 (en) | 1982-07-30 | 1984-02-02 | Siemens AG, 1000 Berlin und 8000 München | METHOD FOR DETERMINING THE CONCENTRATION OF ELECTROCHEMICALLY IMPLEMENTABLE SUBSTANCES |
US4571292A (en) * | 1982-08-12 | 1986-02-18 | Case Western Reserve University | Apparatus for electrochemical measurements |
US4467386A (en) | 1982-11-17 | 1984-08-21 | Rca Corporation | Fail-safe sensor circuit |
DE3245318C3 (en) | 1982-12-08 | 1996-06-20 | Bayer Ag | Process for carrying out pressure reactions with suspended catalysts |
US4679562A (en) | 1983-02-16 | 1987-07-14 | Cardiac Pacemakers, Inc. | Glucose sensor |
US5509410A (en) | 1983-06-06 | 1996-04-23 | Medisense, Inc. | Strip electrode including screen printing of a single layer |
CA1226036A (en) | 1983-05-05 | 1987-08-25 | Irving J. Higgins | Analytical equipment and sensor electrodes therefor |
US5682884A (en) | 1983-05-05 | 1997-11-04 | Medisense, Inc. | Strip electrode with screen printing |
CA1219040A (en) | 1983-05-05 | 1987-03-10 | Elliot V. Plotkin | Measurement of enzyme-catalysed reactions |
DE3326689A1 (en) | 1983-07-23 | 1985-01-31 | Boehringer Mannheim Gmbh, 6800 Mannheim | METHOD AND DEVICE FOR PRODUCING A TEST STRIP |
US4517291A (en) | 1983-08-15 | 1985-05-14 | E. I. Du Pont De Nemours And Company | Biological detection process using polymer-coated electrodes |
US4552458A (en) | 1983-10-11 | 1985-11-12 | Eastman Kodak Company | Compact reflectometer |
SE8305704D0 (en) * | 1983-10-18 | 1983-10-18 | Leo Ab | Cuvette |
US4703017C1 (en) | 1984-02-14 | 2001-12-04 | Becton Dickinson Co | Solid phase assay with visual readout |
DE3407754A1 (en) | 1984-03-02 | 1985-09-12 | Boehringer Mannheim Gmbh, 6800 Mannheim | DEVICE FOR DETERMINING THE DIFFUSION REFLECTIVITY OF A SAMPLE AREA OF SMALL DIMENSIONS |
GB8406752D0 (en) | 1984-03-15 | 1984-04-18 | Unilever Plc | Chemical and clinical tests |
US4849330A (en) | 1984-04-27 | 1989-07-18 | Molecular Devices Corporation | Photoresponsive redox detection and discrimination |
US5141868A (en) | 1984-06-13 | 1992-08-25 | Internationale Octrooi Maatschappij "Octropa" Bv | Device for use in chemical test procedures |
AU583040B2 (en) | 1984-06-13 | 1989-04-20 | Applied Research Systems Ars Holding N.V. | Devices for use in chemical test procedures |
JPS6134031A (en) | 1984-07-26 | 1986-02-18 | Nippon Paint Co Ltd | Surface treatment apparatus |
US4820399A (en) | 1984-08-31 | 1989-04-11 | Shimadzu Corporation | Enzyme electrodes |
US4648665A (en) * | 1984-10-16 | 1987-03-10 | Amp Incorporated | Electronic key assemblies |
AU581701B2 (en) | 1984-10-31 | 1989-03-02 | Inverness Medical Switzerland Gmbh | Apparatus for use in electrical, e.g. electrochemical, measurement procedures, and its production and use, and composite assemblies incorporating the apparatus |
US4713347A (en) | 1985-01-14 | 1987-12-15 | Sensor Diagnostics, Inc. | Measurement of ligand/anti-ligand interactions using bulk conductance |
GB8504521D0 (en) | 1985-02-21 | 1985-03-27 | Genetics Int Inc | Electrochemical assay |
US5279294A (en) * | 1985-04-08 | 1994-01-18 | Cascade Medical, Inc. | Medical diagnostic system |
US4652830A (en) * | 1985-04-18 | 1987-03-24 | Eg&G Ocean Products, Inc. | Analyzer for comparative measurements of bulk conductivity |
US4671288A (en) | 1985-06-13 | 1987-06-09 | The Regents Of The University Of California | Electrochemical cell sensor for continuous short-term use in tissues and blood |
WO1986007632A1 (en) | 1985-06-21 | 1986-12-31 | Matsushita Electric Industrial Co., Ltd. | Biosensor and method of manufacturing same |
US4938860A (en) | 1985-06-28 | 1990-07-03 | Miles Inc. | Electrode for electrochemical sensors |
DE3525986A1 (en) * | 1985-07-20 | 1987-01-29 | Hochtemperatur Kernkraftwerk | LIQUID SUPPLY AS A RBER PRESSURE VALVE |
US4686479A (en) | 1985-07-22 | 1987-08-11 | Young Chung C | Apparatus and control kit for analyzing blood sample values including hematocrit |
US4806311A (en) * | 1985-08-28 | 1989-02-21 | Miles Inc. | Multizone analytical element having labeled reagent concentration zone |
US4806312A (en) * | 1985-08-28 | 1989-02-21 | Miles Inc. | Multizone analytical element having detectable signal concentrating zone |
US4734184A (en) * | 1985-08-29 | 1988-03-29 | Diamond Sensor Systems, Inc. | Self-activating hydratable solid-state electrode apparatus |
US4805624A (en) * | 1985-09-09 | 1989-02-21 | The Montefiore Hospital Association Of Western Pa | Low-potential electrochemical redox sensors |
EP0215669A3 (en) | 1985-09-17 | 1989-08-30 | Seiko Instruments Inc. | Analytical device and method for analysis of biochemicals, microbes and cells |
US5500350A (en) * | 1985-10-30 | 1996-03-19 | Celltech Limited | Binding assay device |
US4714874A (en) | 1985-11-12 | 1987-12-22 | Miles Inc. | Test strip identification and instrument calibration |
US4935106A (en) | 1985-11-15 | 1990-06-19 | Smithkline Diagnostics, Inc. | Ion selective/enzymatic electrode medical analyzer device and method of use |
GB8608700D0 (en) | 1986-04-10 | 1986-05-14 | Genetics Int Inc | Measurement of electroactive species in solution |
US4795542A (en) * | 1986-04-24 | 1989-01-03 | St. Jude Medical, Inc. | Electrochemical concentration detector device |
FR2598227B1 (en) | 1986-04-30 | 1989-07-28 | Bio Merieux | METHOD FOR DETECTION AND / OR IDENTIFICATION OF A BIOLOGICAL SUBSTANCE IN A LIQUID MEDIUM USING ELECTRICAL MEASUREMENTS, AND DEVICE FOR CARRYING OUT SAID METHOD |
US5066372A (en) | 1986-05-02 | 1991-11-19 | Ciba Corning Diagnostics Corp. | Unitary multiple electrode sensor |
US4703756A (en) | 1986-05-06 | 1987-11-03 | The Regents Of The University Of California | Complete glucose monitoring system with an implantable, telemetered sensor module |
US5324335A (en) | 1986-05-08 | 1994-06-28 | Rentech, Inc. | Process for the production of hydrocarbons |
US4731726A (en) * | 1986-05-19 | 1988-03-15 | Healthware Corporation | Patient-operated glucose monitor and diabetes management system |
GB8612861D0 (en) | 1986-05-27 | 1986-07-02 | Cambridge Life Sciences | Immobilised enzyme biosensors |
US4750496A (en) | 1987-01-28 | 1988-06-14 | Xienta, Inc. | Method and apparatus for measuring blood glucose concentration |
JPS636451A (en) | 1986-06-27 | 1988-01-12 | Terumo Corp | Enzyme sensor |
GB8618022D0 (en) | 1986-07-23 | 1986-08-28 | Unilever Plc | Electrochemical measurements |
US5059394A (en) | 1986-08-13 | 1991-10-22 | Lifescan, Inc. | Analytical device for the automated determination of analytes in fluids |
US4935346A (en) | 1986-08-13 | 1990-06-19 | Lifescan, Inc. | Minimum procedure system for the determination of analytes |
US5049487A (en) | 1986-08-13 | 1991-09-17 | Lifescan, Inc. | Automated initiation of timing of reflectance readings |
US4865873A (en) | 1986-09-15 | 1989-09-12 | General Electric Company | Electroless deposition employing laser-patterned masking layer |
US4897162A (en) * | 1986-11-14 | 1990-01-30 | The Cleveland Clinic Foundation | Pulse voltammetry |
DE3643263A1 (en) | 1986-12-18 | 1988-07-07 | Horst Dipl Ing Hommel | Method and device for identifying metabolic disturbances by examination of the urine, in particular for early identification of a tendency to lithogenesis in the urine donor |
JPH039267Y2 (en) * | 1986-12-27 | 1991-03-07 | ||
GB2201248B (en) | 1987-02-24 | 1991-04-17 | Ici Plc | Enzyme electrode sensors |
US4759828A (en) | 1987-04-09 | 1988-07-26 | Nova Biomedical Corporation | Glucose electrode and method of determining glucose |
CA1315181C (en) | 1987-04-13 | 1993-03-30 | Joel M. Blatt | Test strip device with volume metering capillary gap |
US4956275A (en) | 1987-04-14 | 1990-09-11 | Molecular Devices Corporation | Migratory detection immunoassay |
EP0290683A3 (en) | 1987-05-01 | 1988-12-14 | Diva Medical Systems B.V. | Diabetes management system and apparatus |
DE3715938A1 (en) | 1987-05-13 | 1988-11-24 | Boehringer Mannheim Gmbh | CONTAINER FOR TEST STRIP |
US4975647A (en) | 1987-06-01 | 1990-12-04 | Nova Biomedical Corporation | Controlling machine operation with respect to consumable accessory units |
US4797256A (en) * | 1987-06-05 | 1989-01-10 | Boehringer Mannheim Corporation | Registration device for blood test strips |
US5447837A (en) | 1987-08-05 | 1995-09-05 | Calypte, Inc. | Multi-immunoassay diagnostic system for antigens or antibodies or both |
US4812210A (en) | 1987-10-16 | 1989-03-14 | The United States Department Of Energy | Measuring surfactant concentration in plating solutions |
US4929426A (en) | 1987-11-02 | 1990-05-29 | Biologix, Inc. | Portable blood chemistry measuring apparatus |
US4940945A (en) | 1987-11-02 | 1990-07-10 | Biologix Inc. | Interface circuit for use in a portable blood chemistry measuring apparatus |
DE3742786A1 (en) | 1987-12-17 | 1989-06-29 | Boehringer Mannheim Gmbh | ANALYSIS SYSTEM FOR DETERMINING A COMPONENT OF A LIQUID |
US4832814A (en) | 1987-12-28 | 1989-05-23 | E. I. Du Pont De Nemours And Company | Electrofusion cell and method of making the same |
US4877580A (en) | 1988-02-09 | 1989-10-31 | Technimed Corporation | Assay kit including an analyte test strip and a color comparator |
JP2641236B2 (en) | 1988-03-09 | 1997-08-13 | 雪印乳業株式会社 | Sterilization method of immobilized biocatalyst and reactor with fluidized tank |
US5128015A (en) | 1988-03-15 | 1992-07-07 | Tall Oak Ventures | Method and apparatus for amperometric diagnostic analysis |
US5108564A (en) | 1988-03-15 | 1992-04-28 | Tall Oak Ventures | Method and apparatus for amperometric diagnostic analysis |
DE68924026T3 (en) | 1988-03-31 | 2008-01-10 | Matsushita Electric Industrial Co., Ltd., Kadoma | BIOSENSOR AND ITS MANUFACTURE. |
US4954087A (en) | 1988-04-27 | 1990-09-04 | I-Stat Corporation | Static-free interrogating connector for electric components |
US5112758A (en) | 1988-05-09 | 1992-05-12 | Epitope, Inc. | Treating body fluids for diagnostic testing |
US5075077A (en) | 1988-08-02 | 1991-12-24 | Abbott Laboratories | Test card for performing assays |
ATE134040T1 (en) | 1988-08-02 | 1996-02-15 | Abbott Lab | METHOD AND DEVICE FOR GENERATING CALIBRATION DATA FOR ANALYSIS |
US5096669A (en) * | 1988-09-15 | 1992-03-17 | I-Stat Corporation | Disposable sensing device for real time fluid analysis |
US5439826A (en) | 1988-12-02 | 1995-08-08 | Bio-Tek Instruments, Inc. | Method of distinguishing among strips for different assays in an automated instrument |
US5039618A (en) | 1989-02-02 | 1991-08-13 | Hybrivet Systems, Inc. | Test swab cartridge type device and method for detecting lead and cadmium |
US5118183A (en) | 1989-02-10 | 1992-06-02 | X-Rite, Incorporated | Automated strip reader densitometer |
JP2654682B2 (en) | 1989-02-17 | 1997-09-17 | 富士写真フイルム株式会社 | Biochemical analyzer, biochemical analysis correction method and correction value recording medium |
US5053199A (en) | 1989-02-21 | 1991-10-01 | Boehringer Mannheim Corporation | Electronically readable information carrier |
US5269891A (en) | 1989-03-09 | 1993-12-14 | Novo Nordisk A/S | Method and apparatus for determination of a constituent in a fluid |
US5312762A (en) | 1989-03-13 | 1994-05-17 | Guiseppi Elie Anthony | Method of measuring an analyte by measuring electrical resistance of a polymer film reacting with the analyte |
DE3910262C1 (en) | 1989-03-30 | 1990-11-08 | Deutsche Gesellschaft Fuer Wiederaufarbeitung Von Kernbrennstoffen Mbh, 3000 Hannover, De | |
DE3911539A1 (en) | 1989-04-08 | 1990-10-11 | Boehringer Mannheim Gmbh | TEST CARRIER ANALYSIS SYSTEM |
US4960546B1 (en) | 1989-04-19 | 1996-04-09 | Environmental Dynamics Inc | Diffuser mounting arrangement for waste water aeration systems |
US5234813A (en) | 1989-05-17 | 1993-08-10 | Actimed Laboratories, Inc. | Method and device for metering of fluid samples and detection of analytes therein |
DD301250A7 (en) | 1989-05-24 | 1992-11-05 | Akad Wissenschaften Ddr | Measuring apparatus and method for automatically determining the concentration of biocatalyst substrates |
CH677149A5 (en) | 1989-07-07 | 1991-04-15 | Disetronic Ag | |
US4976724A (en) | 1989-08-25 | 1990-12-11 | Lifescan, Inc. | Lancet ejector mechanism |
US5306623A (en) | 1989-08-28 | 1994-04-26 | Lifescan, Inc. | Visual blood glucose concentration test strip |
US6395227B1 (en) | 1989-08-28 | 2002-05-28 | Lifescan, Inc. | Test strip for measuring analyte concentration over a broad range of sample volume |
US5620863A (en) | 1989-08-28 | 1997-04-15 | Lifescan, Inc. | Blood glucose strip having reduced side reactions |
AU640162B2 (en) | 1989-08-28 | 1993-08-19 | Lifescan, Inc. | Blood separation and analyte detection techniques |
US5018164A (en) | 1989-09-12 | 1991-05-21 | Hughes Aircraft Company | Excimer laser ablation method and apparatus for microcircuit fabrication |
JP2665806B2 (en) | 1989-09-13 | 1997-10-22 | 株式会社豊田中央研究所 | Hematocrit measuring device |
US5639671A (en) | 1989-09-18 | 1997-06-17 | Biostar, Inc. | Methods for optimizing of an optical assay device |
DE3940152A1 (en) | 1989-12-05 | 1991-06-06 | Boehringer Mannheim Gmbh | TEST STRIP EVALUATOR FOR MULTIPLE TEST STRIPS |
US5243516A (en) | 1989-12-15 | 1993-09-07 | Boehringer Mannheim Corporation | Biosensing instrument and method |
US4999582A (en) * | 1989-12-15 | 1991-03-12 | Boehringer Mannheim Corp. | Biosensor electrode excitation circuit |
WO1991009139A1 (en) * | 1989-12-15 | 1991-06-27 | Boehringer Mannheim Corporation | Redox mediator reagent and biosensor |
US4999632A (en) * | 1989-12-15 | 1991-03-12 | Boehringer Mannheim Corporation | Analog to digital conversion with noise reduction |
US5508171A (en) | 1989-12-15 | 1996-04-16 | Boehringer Mannheim Corporation | Assay method with enzyme electrode system |
US4963814A (en) | 1989-12-15 | 1990-10-16 | Boehringer Mannheim Corporation | Regulated bifurcated power supply |
US5286362A (en) * | 1990-02-03 | 1994-02-15 | Boehringer Mannheim Gmbh | Method and sensor electrode system for the electrochemical determination of an analyte or an oxidoreductase as well as the use of suitable compounds therefor |
DE4003194A1 (en) | 1990-02-03 | 1991-08-08 | Boehringer Mannheim Gmbh | Electrochemical determn. of analytes - using oxido-reductase and substance of being reduced, which is re-oxidised on the electrode |
US5141850A (en) | 1990-02-07 | 1992-08-25 | Hygeia Sciences, Inc. | Porous strip form assay device method |
US5187100A (en) * | 1990-05-29 | 1993-02-16 | Lifescan, Inc. | Dispersion to limit penetration of aqueous solutions into a membrane |
US5250439A (en) | 1990-07-19 | 1993-10-05 | Miles Inc. | Use of conductive sensors in diagnostic assays |
JPH0820412B2 (en) * | 1990-07-20 | 1996-03-04 | 松下電器産業株式会社 | Quantitative analysis method and device using disposable sensor |
US5112455A (en) | 1990-07-20 | 1992-05-12 | I Stat Corporation | Method for analytically utilizing microfabricated sensors during wet-up |
US5182707A (en) * | 1990-07-23 | 1993-01-26 | Healthdyne, Inc. | Apparatus for recording reagent test strip data by comparison to color lights on a reference panel |
US5124661A (en) | 1990-07-23 | 1992-06-23 | I-Stat Corporation | Reusable test unit for simulating electrochemical sensor signals for quality assurance of portable blood analyzer instruments |
US5569591A (en) | 1990-08-03 | 1996-10-29 | University College Of Wales Aberystwyth | Analytical or monitoring apparatus and method |
US5120421A (en) | 1990-08-31 | 1992-06-09 | The United States Of America As Represented By The United States Department Of Energy | Electrochemical sensor/detector system and method |
US5526808A (en) | 1990-10-04 | 1996-06-18 | Microcor, Inc. | Method and apparatus for noninvasively determining hematocrit |
US5642734A (en) | 1990-10-04 | 1997-07-01 | Microcor, Inc. | Method and apparatus for noninvasively determining hematocrit |
DE4041905A1 (en) * | 1990-12-27 | 1992-07-02 | Boehringer Mannheim Gmbh | TEST CARRIER ANALYSIS SYSTEM |
US5126952A (en) | 1991-01-22 | 1992-06-30 | Eastman Kodak Company | Bar coding calibration |
US5246858A (en) | 1991-02-27 | 1993-09-21 | Boehringer Mannheim Corporation | Apparatus and method for analyzing a body fluid |
ES2210231T3 (en) * | 1991-02-27 | 2004-07-01 | Roche Diagnostics Corporation | APPARATUS AND METHOD FOR ANALYSIS OF BODY FLUIDS. |
WO1992015950A1 (en) * | 1991-02-27 | 1992-09-17 | Boehringer Mannheim Corporation | Method of communicating with microcomputer controlled instruments |
US5232668A (en) | 1991-02-27 | 1993-08-03 | Boehringer Mannheim Corporation | Test strip holding and reading mechanism for a meter |
US5192415A (en) * | 1991-03-04 | 1993-03-09 | Matsushita Electric Industrial Co., Ltd. | Biosensor utilizing enzyme and a method for producing the same |
US5593852A (en) * | 1993-12-02 | 1997-01-14 | Heller; Adam | Subcutaneous glucose electrode |
DE4117847A1 (en) | 1991-05-31 | 1992-12-03 | Lre Relais & Elektronik Gmbh | Evaluating bar coded optical information - subjecting output from sensor to peak and min. valve generation with comparison process |
US5232516A (en) | 1991-06-04 | 1993-08-03 | Implemed, Inc. | Thermoelectric device with recuperative heat exchangers |
GB9113211D0 (en) * | 1991-06-19 | 1991-08-07 | Hypoguard Uk Ltd | Support membrane |
DE4123348A1 (en) * | 1991-07-15 | 1993-01-21 | Boehringer Mannheim Gmbh | ELECTROCHEMICAL ANALYSIS SYSTEM |
US5179288A (en) * | 1991-09-30 | 1993-01-12 | Ortho Pharmaceutical Corporation | Apparatus and method for measuring a bodily constituent |
US5264103A (en) | 1991-10-18 | 1993-11-23 | Matsushita Electric Industrial Co., Ltd. | Biosensor and a method for measuring a concentration of a substrate in a sample |
JP2960265B2 (en) * | 1991-10-18 | 1999-10-06 | 松下電器産業株式会社 | Biosensor and measurement method using the same |
US5605662A (en) * | 1993-11-01 | 1997-02-25 | Nanogen, Inc. | Active programmable electronic devices for molecular biological analysis and diagnostics |
US5220920A (en) | 1991-11-08 | 1993-06-22 | Via Medical Corporation | Electrochemical measurement system having interference reduction circuit |
IL103674A0 (en) | 1991-11-19 | 1993-04-04 | Houston Advanced Res Center | Method and apparatus for molecule detection |
JP3135959B2 (en) | 1991-12-12 | 2001-02-19 | アークレイ株式会社 | Biosensor and separation and quantification method using the same |
US5217594A (en) | 1992-01-15 | 1993-06-08 | Enzyme Technology Research Group, Inc. | Convenient determination of trace lead in whole blood and other fluids |
JP3342077B2 (en) | 1992-02-03 | 2002-11-05 | ライフスキヤン・インコーポレーテツド | Improved oxidative coupling dyes for spectrophotometric determination of analytes |
US5635364A (en) | 1992-03-27 | 1997-06-03 | Abbott Laboratories | Assay verification control for an automated analytical system |
US5296192A (en) * | 1992-04-03 | 1994-03-22 | Home Diagnostics, Inc. | Diagnostic test strip |
US5353351A (en) | 1992-06-09 | 1994-10-04 | At&T Bell Laboratories | Secure teleconferencing |
GB9215733D0 (en) | 1992-07-24 | 1992-09-09 | British Tech Group | Method of and apparatus for determining a property of a sample |
CA2105940C (en) | 1992-10-05 | 2001-12-25 | Robert M. Koros | Bubble column, tube side slurry process and apparatus |
US5508200A (en) | 1992-10-19 | 1996-04-16 | Tiffany; Thomas | Method and apparatus for conducting multiple chemical assays |
US5387327A (en) | 1992-10-19 | 1995-02-07 | Duquesne University Of The Holy Ghost | Implantable non-enzymatic electrochemical glucose sensor |
US5342790A (en) | 1992-10-30 | 1994-08-30 | Becton Dickinson And Company | Apparatus for indirect fluorescent assay of blood samples |
US5389215A (en) * | 1992-11-05 | 1995-02-14 | Nippon Telegraph And Telephone Corporation | Electrochemical detection method and apparatus therefor |
JP2954436B2 (en) | 1992-11-11 | 1999-09-27 | 株式会社日立製作所 | Test piece supply device and analyzer using the same |
US6168563B1 (en) * | 1992-11-17 | 2001-01-02 | Health Hero Network, Inc. | Remote health monitoring and maintenance system |
US5371687A (en) * | 1992-11-20 | 1994-12-06 | Boehringer Mannheim Corporation | Glucose test data acquisition and management system |
ZA938555B (en) | 1992-11-23 | 1994-08-02 | Lilly Co Eli | Technique to improve the performance of electrochemical sensors |
US5344754A (en) | 1993-01-13 | 1994-09-06 | Avocet Medical, Inc. | Assay timed by electrical resistance change and test strip |
US5599849A (en) | 1993-01-27 | 1997-02-04 | Sasol Chemical Industries (Proprietary) Limited | Process for producing liquid and, optionally, gaseous products from gaseous reactants |
US5515847A (en) | 1993-01-28 | 1996-05-14 | Optiscan, Inc. | Self-emission noninvasive infrared spectrophotometer |
FR2701117B1 (en) * | 1993-02-04 | 1995-03-10 | Asulab Sa | Electrochemical measurement system with multizone sensor, and its application to glucose measurement. |
IL109159A (en) | 1993-03-29 | 2003-11-23 | Isk Biotech Corp | Immunoassays for tetrachloroiso-phthalonitrile and its metabolites and antibodies for use therein |
DE4310583A1 (en) | 1993-03-31 | 1994-10-06 | Boehringer Mannheim Gmbh | Test strip analysis system |
DE4313253A1 (en) | 1993-04-23 | 1994-10-27 | Boehringer Mannheim Gmbh | System for analyzing the contents of liquid samples |
DK0622119T3 (en) * | 1993-04-23 | 2000-04-10 | Roche Diagnostics Gmbh | Test element storage system |
US5376254A (en) | 1993-05-14 | 1994-12-27 | Fisher; Arkady V. | Potentiometric electrochemical device for qualitative and quantitative analysis |
US5843691A (en) | 1993-05-15 | 1998-12-01 | Lifescan, Inc. | Visually-readable reagent test strip |
ES2107833T3 (en) | 1993-05-29 | 1997-12-01 | Cambridge Life Sciences | SENSORS BASED ON TRANSFORMATION OF POLYMERS. |
US5385846A (en) * | 1993-06-03 | 1995-01-31 | Boehringer Mannheim Corporation | Biosensor and method for hematocrit determination |
DE4318519C2 (en) | 1993-06-03 | 1996-11-28 | Fraunhofer Ges Forschung | Electrochemical sensor |
US5405511A (en) | 1993-06-08 | 1995-04-11 | Boehringer Mannheim Corporation | Biosensing meter with ambient temperature estimation method and system |
US5352351A (en) * | 1993-06-08 | 1994-10-04 | Boehringer Mannheim Corporation | Biosensing meter with fail/safe procedures to prevent erroneous indications |
US5366609A (en) | 1993-06-08 | 1994-11-22 | Boehringer Mannheim Corporation | Biosensing meter with pluggable memory key |
ES2153335T3 (en) * | 1993-06-08 | 2006-09-01 | Roche Diagnostics Operations, Inc. | BIOSENSOR METER THAT DETECTS THE PROPER ADJUSTMENT OF THE ELECTRODES AND DISTINGUISHES SAMPLING STRIPS AND CHECKING STRIPS. |
US5527473A (en) | 1993-07-15 | 1996-06-18 | Ackerman; Carl D. | Process for performing reactions in a liquid-solid catalyst slurry |
DE4323672A1 (en) | 1993-07-15 | 1995-01-19 | Boehringer Mannheim Gmbh | Device for the simultaneous determination of analytes |
US5658443A (en) | 1993-07-23 | 1997-08-19 | Matsushita Electric Industrial Co., Ltd. | Biosensor and method for producing the same |
US5413690A (en) | 1993-07-23 | 1995-05-09 | Boehringer Mannheim Corporation | Potentiometric biosensor and the method of its use |
US5748002A (en) | 1996-01-26 | 1998-05-05 | Phase Dynamics Inc. | RF probe for montoring composition of substances |
US5792668A (en) | 1993-08-06 | 1998-08-11 | Solid State Farms, Inc. | Radio frequency spectral analysis for in-vitro or in-vivo environments |
US5508203A (en) | 1993-08-06 | 1996-04-16 | Fuller; Milton E. | Apparatus and method for radio frequency spectroscopy using spectral analysis |
US5837546A (en) | 1993-08-24 | 1998-11-17 | Metrika, Inc. | Electronic assay device and method |
JP3035352B2 (en) | 1993-08-24 | 2000-04-24 | メトリカ・インコーポレーテッド | New disposable electronic test device |
US5494831A (en) | 1993-08-30 | 1996-02-27 | Hughes Aircraft Company | Electrochemical immunosensor system and methods |
ES2180588T3 (en) | 1993-08-31 | 2003-02-16 | Roche Diagnostics Corp | ANALOG HEATER CONTROL FOR MEDICAL INSTRUMENT. |
US5522255A (en) * | 1993-08-31 | 1996-06-04 | Boehringer Mannheim Corporation | Fluid dose, flow and coagulation sensor for medical instrument |
US5526111A (en) | 1993-08-31 | 1996-06-11 | Boehringer Mannheim Corporation | Method and apparatus for calculating a coagulation characteristic of a sample of blood a blood fraction or a control |
US5437772A (en) | 1993-11-01 | 1995-08-01 | The Electrosynthesis Co., Inc. | Portable lead detector |
JPH07128338A (en) | 1993-11-02 | 1995-05-19 | Kyoto Daiichi Kagaku:Kk | Convenient blood sugar meter and data managing method therefor |
US5421189A (en) | 1994-01-21 | 1995-06-06 | Ciba Corning Diagnostics Corp. | Electrical connection system for electrochemical sensors |
US5762770A (en) | 1994-02-21 | 1998-06-09 | Boehringer Mannheim Corporation | Electrochemical biosensor test strip |
US5437999A (en) | 1994-02-22 | 1995-08-01 | Boehringer Mannheim Corporation | Electrochemical sensor |
US5536249A (en) | 1994-03-09 | 1996-07-16 | Visionary Medical Products, Inc. | Pen-type injector with a microprocessor and blood characteristic monitor |
US5583432A (en) | 1994-04-11 | 1996-12-10 | Sci-Nostics Limited | Electrical method and apparatus for non-contact determination of physical and/or chemical properties of a sample, particularly of blood |
DE4417245A1 (en) | 1994-04-23 | 1995-10-26 | Lpkf Cad Cam Systeme Gmbh | High resolution structured metallisation prodn. |
JP3331253B2 (en) | 1994-05-10 | 2002-10-07 | バイエルコーポレーション | Test strip removal device for automatic analyzer |
JP3027306B2 (en) | 1994-06-02 | 2000-04-04 | 松下電器産業株式会社 | Biosensor and manufacturing method thereof |
US5477326A (en) | 1994-06-30 | 1995-12-19 | Bayer Corporation | Spectrophotometer arrangement with multi-detector readhead |
US5700695A (en) | 1994-06-30 | 1997-12-23 | Zia Yassinzadeh | Sample collection and manipulation method |
GB9415499D0 (en) | 1994-08-01 | 1994-09-21 | Bartlett Philip N | Electrodes and their use in analysis |
US5922530A (en) | 1994-09-08 | 1999-07-13 | Lifescan, Inc. | Stable coupling dye for photometric determination of analytes |
US5515170A (en) | 1994-09-08 | 1996-05-07 | Lifescan, Inc. | Analyte detection device having a serpentine passageway for indicator strips |
US5526120A (en) | 1994-09-08 | 1996-06-11 | Lifescan, Inc. | Test strip with an asymmetrical end insuring correct insertion for measuring |
US5563031A (en) | 1994-09-08 | 1996-10-08 | Lifescan, Inc. | Highly stable oxidative coupling dye for spectrophotometric determination of analytes |
US6335203B1 (en) | 1994-09-08 | 2002-01-01 | Lifescan, Inc. | Optically readable strip for analyte detection having on-strip orientation index |
ES2168389T3 (en) | 1994-09-08 | 2002-06-16 | Lifescan Inc | STRIP OF OPTICAL READING AND INCORPORATED PATTERN FOR THE DETECTION OF AN ANALYTE. |
GB9419882D0 (en) | 1994-10-03 | 1994-11-16 | Mcnaughtan Arthur | Electrochemical detection system |
US5597532A (en) * | 1994-10-20 | 1997-01-28 | Connolly; James | Apparatus for determining substances contained in a body fluid |
US5504011A (en) | 1994-10-21 | 1996-04-02 | International Technidyne Corporation | Portable test apparatus and associated method of performing a blood coagulation test |
IE72524B1 (en) | 1994-11-04 | 1997-04-23 | Elan Med Tech | Analyte-controlled liquid delivery device and analyte monitor |
US5572159A (en) | 1994-11-14 | 1996-11-05 | Nexgen, Inc. | Voltage-controlled delay element with programmable delay |
KR0151203B1 (en) | 1994-12-08 | 1998-12-01 | 이헌조 | Multi-electrode type biosensor |
US5630986A (en) | 1995-01-13 | 1997-05-20 | Bayer Corporation | Dispensing instrument for fluid monitoring sensors |
US5569608A (en) | 1995-01-30 | 1996-10-29 | Bayer Corporation | Quantitative detection of analytes on immunochromatographic strips |
US6153069A (en) | 1995-02-09 | 2000-11-28 | Tall Oak Ventures | Apparatus for amperometric Diagnostic analysis |
EP0727925A1 (en) * | 1995-02-14 | 1996-08-21 | Lpkf Cad/Cam Systeme Gmbh | Process for structured metallizing of the surface of substrates |
US5567301A (en) | 1995-03-01 | 1996-10-22 | Illinois Institute Of Technology | Antibody covalently bound film immunobiosensor |
US5650062A (en) | 1995-03-17 | 1997-07-22 | Matsushita Electric Industrial Co., Ltd. | Biosensor, and a method and a device for quantifying a substrate in a sample liquid using the same |
US5582697A (en) | 1995-03-17 | 1996-12-10 | Matsushita Electric Industrial Co., Ltd. | Biosensor, and a method and a device for quantifying a substrate in a sample liquid using the same |
US6170318B1 (en) * | 1995-03-27 | 2001-01-09 | California Institute Of Technology | Methods of use for sensor based fluid detection devices |
US5788833A (en) | 1995-03-27 | 1998-08-04 | California Institute Of Technology | Sensors for detecting analytes in fluids |
JP3498105B2 (en) * | 1995-04-07 | 2004-02-16 | アークレイ株式会社 | Sensor, method for manufacturing the same, and measuring method using the sensor |
US5620579A (en) | 1995-05-05 | 1997-04-15 | Bayer Corporation | Apparatus for reduction of bias in amperometric sensors |
US5656502A (en) | 1995-06-07 | 1997-08-12 | Diagnostic Chemicals Limited | Test strip holder and method of use |
AUPN363995A0 (en) | 1995-06-19 | 1995-07-13 | Memtec Limited | Electrochemical cell |
US6413410B1 (en) | 1996-06-19 | 2002-07-02 | Lifescan, Inc. | Electrochemical cell |
US5856174A (en) | 1995-06-29 | 1999-01-05 | Affymetrix, Inc. | Integrated nucleic acid diagnostic device |
US5611900A (en) | 1995-07-20 | 1997-03-18 | Michigan State University | Microbiosensor used in-situ |
US5698083A (en) | 1995-08-18 | 1997-12-16 | Regents Of The University Of California | Chemiresistor urea sensor |
WO1997008544A1 (en) * | 1995-08-22 | 1997-03-06 | Andcare, Inc. | Handheld electromonitor device |
US5786584A (en) | 1995-09-06 | 1998-07-28 | Eli Lilly And Company | Vial and cartridge reading device providing audio feedback for a blood glucose monitoring system |
US5658802A (en) | 1995-09-07 | 1997-08-19 | Microfab Technologies, Inc. | Method and apparatus for making miniaturized diagnostic arrays |
US5650061A (en) | 1995-09-18 | 1997-07-22 | The Regents Of The University Of California | Large amplitude sinusoidal voltammetry |
US5665215A (en) | 1995-09-25 | 1997-09-09 | Bayer Corporation | Method and apparatus for making predetermined events with a biosensor |
US5628890A (en) | 1995-09-27 | 1997-05-13 | Medisense, Inc. | Electrochemical sensor |
US6689265B2 (en) | 1995-10-11 | 2004-02-10 | Therasense, Inc. | Electrochemical analyte sensors using thermostable soybean peroxidase |
AU722471B2 (en) | 1995-10-17 | 2000-08-03 | Lifescan, Inc. | Blood glucose strip having reduced sensitivity to hematocrit |
US6777243B2 (en) | 1995-10-30 | 2004-08-17 | Arkray Inc. | Method for measuring substance and testing piece |
US6863801B2 (en) | 1995-11-16 | 2005-03-08 | Lifescan, Inc. | Electrochemical cell |
US6174420B1 (en) * | 1996-11-15 | 2001-01-16 | Usf Filtration And Separations Group, Inc. | Electrochemical cell |
US6638415B1 (en) | 1995-11-16 | 2003-10-28 | Lifescan, Inc. | Antioxidant sensor |
AUPN661995A0 (en) * | 1995-11-16 | 1995-12-07 | Memtec America Corporation | Electrochemical cell 2 |
US6521110B1 (en) * | 1995-11-16 | 2003-02-18 | Lifescan, Inc. | Electrochemical cell |
JPH09207343A (en) | 1995-11-29 | 1997-08-12 | Matsushita Electric Ind Co Ltd | Laser machining method |
US5755953A (en) | 1995-12-18 | 1998-05-26 | Abbott Laboratories | Interference free biosensor |
JP3365184B2 (en) | 1996-01-10 | 2003-01-08 | 松下電器産業株式会社 | Biosensor |
CA2245664A1 (en) * | 1996-02-08 | 1997-08-14 | Australian Membrane And Biotechnology Research Institute | Enzyme detection biosensors |
US5989917A (en) | 1996-02-13 | 1999-11-23 | Selfcare, Inc. | Glucose monitor and test strip containers for use in same |
US5708247A (en) * | 1996-02-14 | 1998-01-13 | Selfcare, Inc. | Disposable glucose test strips, and methods and compositions for making same |
US5605837A (en) * | 1996-02-14 | 1997-02-25 | Lifescan, Inc. | Control solution for a blood glucose monitor |
US6241862B1 (en) | 1996-02-14 | 2001-06-05 | Inverness Medical Technology, Inc. | Disposable test strips with integrated reagent/blood separation layer |
DE19605583A1 (en) | 1996-02-15 | 1997-08-21 | Bayer Ag | Electrochemical sensors with improved selectivity and increased sensitivity |
US5801057A (en) | 1996-03-22 | 1998-09-01 | Smart; Wilson H. | Microsampling device and method of construction |
DE19612680C2 (en) | 1996-03-29 | 2000-02-03 | Inst Chemo Biosensorik | Cation selective sensor |
US5723284A (en) | 1996-04-01 | 1998-03-03 | Bayer Corporation | Control solution and method for testing the performance of an electrochemical device for determining the concentration of an analyte in blood |
US5962215A (en) | 1996-04-05 | 1999-10-05 | Mercury Diagnostics, Inc. | Methods for testing the concentration of an analyte in a body fluid |
US5890489A (en) | 1996-04-23 | 1999-04-06 | Dermal Therapy (Barbados) Inc. | Method for non-invasive determination of glucose in body fluids |
US6001307A (en) * | 1996-04-26 | 1999-12-14 | Kyoto Daiichi Kagaku Co., Ltd. | Device for analyzing a sample |
DE19621241C2 (en) * | 1996-05-25 | 2000-03-16 | Manfred Kessler | Membrane electrode for measuring the glucose concentration in liquids |
US5781024A (en) | 1996-07-26 | 1998-07-14 | Diametrics Medical, Inc. | Instrument performance verification system |
US5719667A (en) * | 1996-07-30 | 1998-02-17 | Bayer Corporation | Apparatus for filtering a laser beam in an analytical instrument |
US5883378A (en) | 1996-07-30 | 1999-03-16 | Bayer Corporation | Apparatus and methods for transmitting electrical signals indicative of optical interactions between a light beam and a flowing suspension of particles |
US5745308A (en) | 1996-07-30 | 1998-04-28 | Bayer Corporation | Methods and apparatus for an optical illuminator assembly and its alignment |
US5691486A (en) | 1996-07-30 | 1997-11-25 | Bayer Corporation | Apparatus and methods for selecting a variable number of test sample aliquots to mix with respective reagents |
US5753101A (en) | 1996-08-01 | 1998-05-19 | Ludwig; Frank A. | Method of monitoring constituents in conversion coating baths |
US5958791A (en) | 1996-09-27 | 1999-09-28 | Innovative Biotechnologies, Inc. | Interdigitated electrode arrays for liposome-enhanced immunoassay and test device |
US6358752B1 (en) | 1996-09-27 | 2002-03-19 | Cornell Research Foundation, Inc. | Liposome-enhanced test device and method |
US5925293A (en) | 1996-10-04 | 1999-07-20 | General Signal Corporation | Mixer sparging apparatus |
US5945341A (en) | 1996-10-21 | 1999-08-31 | Bayer Corporation | System for the optical identification of coding on a diagnostic test strip |
GB9622304D0 (en) | 1996-10-26 | 1996-12-18 | Univ Manchester | Sensor |
US5856195A (en) * | 1996-10-30 | 1999-01-05 | Bayer Corporation | Method and apparatus for calibrating a sensor element |
US7381525B1 (en) | 1997-03-07 | 2008-06-03 | Clinical Micro Sensors, Inc. | AC/DC voltage apparatus for detection of nucleic acids |
US6632349B1 (en) | 1996-11-15 | 2003-10-14 | Lifescan, Inc. | Hemoglobin sensor |
WO1998028623A1 (en) | 1996-12-20 | 1998-07-02 | Gamera Bioscience Corporation | An affinity binding-based system for detecting particulates in a fluid |
JP3460183B2 (en) | 1996-12-24 | 2003-10-27 | 松下電器産業株式会社 | Biosensor |
JP3394262B2 (en) | 1997-02-06 | 2003-04-07 | セラセンス、インク. | Small volume in vitro analyte sensor |
EP0859230A1 (en) | 1997-02-10 | 1998-08-19 | Cranfield University | Detection of analytes using electrochemistry |
US6391558B1 (en) | 1997-03-18 | 2002-05-21 | Andcare, Inc. | Electrochemical detection of nucleic acid sequences |
AUPO581397A0 (en) | 1997-03-21 | 1997-04-17 | Memtec America Corporation | Sensor connection means |
US6226081B1 (en) | 1997-03-24 | 2001-05-01 | Optikos Corporation | Optical height of fill detection system and associated methods |
AUPO585797A0 (en) | 1997-03-25 | 1997-04-24 | Memtec America Corporation | Improved electrochemical cell |
DE19714674A1 (en) | 1997-04-09 | 1998-10-15 | Lre Technology Partner Gmbh | Test strip pack and measuring device for using one |
US5885839A (en) | 1997-04-15 | 1999-03-23 | Lxn Corporation | Methods of determining initiation and variable end points for measuring a chemical reaction |
TW344029B (en) | 1997-05-02 | 1998-11-01 | Nat Science Council | Electrochemical sensor for measuring the concentration of hydrogen peroxide and precursor of hydrogen peroxide in liquid and method therefor |
US6103536A (en) | 1997-05-02 | 2000-08-15 | Silver Lake Research Corporation | Internally referenced competitive assays |
US5798031A (en) | 1997-05-12 | 1998-08-25 | Bayer Corporation | Electrochemical biosensor |
US6391645B1 (en) | 1997-05-12 | 2002-05-21 | Bayer Corporation | Method and apparatus for correcting ambient temperature effect in biosensors |
US5921925A (en) | 1997-05-30 | 1999-07-13 | Ndm, Inc. | Biomedical electrode having a disposable electrode and a reusable leadwire adapter that interfaces with a standard leadwire connector |
GB9824627D0 (en) | 1998-11-11 | 1999-01-06 | Cambridge Sensors Ltd | Test strips for small volumes |
US6040195A (en) | 1997-06-10 | 2000-03-21 | Home Diagnostics, Inc. | Diagnostic sanitary test strip |
US6013459A (en) | 1997-06-12 | 2000-01-11 | Clinical Micro Sensors, Inc. | Detection of analytes using reorganization energy |
US6168957B1 (en) * | 1997-06-25 | 2001-01-02 | Lifescan, Inc. | Diagnostic test strip having on-strip calibration |
US6309526B1 (en) | 1997-07-10 | 2001-10-30 | Matsushita Electric Industrial Co., Ltd. | Biosensor |
BR9810794B1 (en) | 1997-07-22 | 2014-10-14 | Arkray Inc | CONCENTRATION MEASURING APPLIANCE. |
JP3297630B2 (en) | 1997-07-28 | 2002-07-02 | 松下電器産業株式会社 | Biosensor |
JP3375040B2 (en) | 1997-07-29 | 2003-02-10 | 松下電器産業株式会社 | Substrate quantification method |
CA2244332C (en) | 1997-07-30 | 2002-04-02 | Becton, Dickinson And Company | Bonding agent and method of bonding electrode to printed conductive trace |
AUPO855897A0 (en) | 1997-08-13 | 1997-09-04 | Usf Filtration And Separations Group Inc. | Automatic analysing apparatus II |
US6121050A (en) | 1997-08-29 | 2000-09-19 | Han; Chi-Neng Arthur | Analyte detection systems |
US6061128A (en) | 1997-09-04 | 2000-05-09 | Avocet Medical, Inc. | Verification device for optical clinical assay systems |
US6129823A (en) | 1997-09-05 | 2000-10-10 | Abbott Laboratories | Low volume electrochemical sensor |
US6071391A (en) | 1997-09-12 | 2000-06-06 | Nok Corporation | Enzyme electrode structure |
US6259937B1 (en) | 1997-09-12 | 2001-07-10 | Alfred E. Mann Foundation | Implantable substrate sensor |
US6007775A (en) | 1997-09-26 | 1999-12-28 | University Of Washington | Multiple analyte diffusion based chemical sensor |
JP2001518622A (en) | 1997-09-30 | 2001-10-16 | アミラ メディカル | Analyzer using capillary reagent carrier |
US6088608A (en) | 1997-10-20 | 2000-07-11 | Alfred E. Mann Foundation | Electrochemical sensor and integrity tests therefor |
FI107080B (en) | 1997-10-27 | 2001-05-31 | Nokia Mobile Phones Ltd | measuring device |
AU1449699A (en) | 1997-10-31 | 1999-05-24 | Technical Chemicals & Products, Inc. | Reflectometer |
US6102872A (en) | 1997-11-03 | 2000-08-15 | Pacific Biometrics, Inc. | Glucose detector and method |
ES2281143T3 (en) | 1997-11-12 | 2007-09-16 | Lightouch Medical, Inc. | METHOD FOR THE NON-INVASIVE MEASUREMENT OF AN ANALYTE. |
DK1034039T3 (en) | 1997-11-28 | 2003-06-02 | Provalis Diagnostics Ltd | Apparatus and system for conducting an analysis |
NZ504879A (en) | 1997-12-04 | 2003-05-30 | Roche Diagnostics Corp | Instrument for engaging a power cell |
US6579690B1 (en) | 1997-12-05 | 2003-06-17 | Therasense, Inc. | Blood analyte monitoring through subcutaneous measurement |
US5997817A (en) * | 1997-12-05 | 1999-12-07 | Roche Diagnostics Corporation | Electrochemical biosensor test strip |
US6162639A (en) | 1997-12-19 | 2000-12-19 | Amira Medical | Embossed test strip system |
US7407811B2 (en) | 1997-12-22 | 2008-08-05 | Roche Diagnostics Operations, Inc. | System and method for analyte measurement using AC excitation |
US6645368B1 (en) * | 1997-12-22 | 2003-11-11 | Roche Diagnostics Corporation | Meter and method of using the meter for determining the concentration of a component of a fluid |
US5971923A (en) | 1997-12-31 | 1999-10-26 | Acuson Corporation | Ultrasound system and method for interfacing with peripherals |
US6262749B1 (en) | 1997-12-31 | 2001-07-17 | Acuson Corporation | Ultrasonic system and method for data transfer, storage and/or processing |
JP3848993B2 (en) | 1998-01-06 | 2006-11-22 | アークレイ株式会社 | Method and apparatus for measuring the amount of components in the presence of coexisting substances |
US6485905B2 (en) | 1998-02-02 | 2002-11-26 | Signature Bioscience, Inc. | Bio-assay device |
US6394952B1 (en) | 1998-02-03 | 2002-05-28 | Adeza Biomedical Corporation | Point of care diagnostic systems |
JP3978489B2 (en) * | 1998-02-26 | 2007-09-19 | アークレイ株式会社 | Blood measuring device |
US6206282B1 (en) | 1998-03-03 | 2001-03-27 | Pyper Products Corporation | RF embedded identification device |
US6103033A (en) | 1998-03-04 | 2000-08-15 | Therasense, Inc. | Process for producing an electrochemical biosensor |
US6134461A (en) | 1998-03-04 | 2000-10-17 | E. Heller & Company | Electrochemical analyte |
US6475360B1 (en) | 1998-03-12 | 2002-11-05 | Lifescan, Inc. | Heated electrochemical cell |
US6878251B2 (en) | 1998-03-12 | 2005-04-12 | Lifescan, Inc. | Heated electrochemical cell |
CA2265119C (en) | 1998-03-13 | 2002-12-03 | Cygnus, Inc. | Biosensor, iontophoretic sampling system, and methods of use thereof |
US5939609A (en) | 1998-03-23 | 1999-08-17 | Conception Technology Incorporated | Multi-use sensor having a controllable number of measurement cycles |
US6091975A (en) | 1998-04-01 | 2000-07-18 | Alza Corporation | Minimally invasive detecting device |
WO1999051974A1 (en) | 1998-04-02 | 1999-10-14 | Matsushita Electric Industrial Co., Ltd. | Substrate determining method |
US6246966B1 (en) | 1998-04-06 | 2001-06-12 | Bayer Corporation | Method and apparatus for data management authentication in a clinical analyzer |
US5995236A (en) | 1998-04-13 | 1999-11-30 | Mit Development Corporation | Blood fluid characteristics analysis instrument |
US6175752B1 (en) | 1998-04-30 | 2001-01-16 | Therasense, Inc. | Analyte monitoring device and methods of use |
US6271044B1 (en) | 1998-05-06 | 2001-08-07 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Method and kit for detecting an analyte |
GB2337122B (en) | 1998-05-08 | 2002-11-13 | Medisense Inc | Test strip |
US6272364B1 (en) | 1998-05-13 | 2001-08-07 | Cygnus, Inc. | Method and device for predicting physiological values |
PT1077634E (en) | 1998-05-13 | 2003-12-31 | Cygnus Therapeutic Systems | MONITORING OF PHYSIOLOGICAL SUBSTANCES TO BE ANALYZED |
US6526298B1 (en) * | 1998-05-18 | 2003-02-25 | Abbott Laboratories | Method for the non-invasive determination of analytes in a selected volume of tissue |
DE29809191U1 (en) | 1998-05-20 | 1998-08-13 | Lre Technology Partner Gmbh | Test strip measuring system |
DE69920006T2 (en) | 1998-05-20 | 2005-09-15 | Arkray, Inc. | METHOD AND DEVICE FOR ELECTROCHEMICAL MEASUREMENTS USING STATISTICAL METHODS |
US6246330B1 (en) | 1998-05-29 | 2001-06-12 | Wyn Y. Nielsen | Elimination-absorber monitoring system |
US6287595B1 (en) | 1998-06-10 | 2001-09-11 | Delsys Pharmaceuticals Corporation | Biomedical assay device |
US6077660A (en) | 1998-06-10 | 2000-06-20 | Abbott Laboratories | Diagnostic assay requiring a small sample of biological fluid |
JP3874321B2 (en) | 1998-06-11 | 2007-01-31 | 松下電器産業株式会社 | Biosensor |
JP3389106B2 (en) * | 1998-06-11 | 2003-03-24 | 松下電器産業株式会社 | Electrochemical analysis element |
US6022366A (en) | 1998-06-11 | 2000-02-08 | Stat Medical Devices Inc. | Lancet having adjustable penetration depth |
US6294281B1 (en) | 1998-06-17 | 2001-09-25 | Therasense, Inc. | Biological fuel cell and method |
WO1999067019A1 (en) * | 1998-06-24 | 1999-12-29 | Therasense, Inc. | Combinatorial electrochemical syntheses |
AU4833899A (en) | 1998-06-24 | 2000-01-10 | Therasense, Inc. | Multi-sensor array for electrochemical recognition of nucleotide sequences and methods |
JP2000019147A (en) | 1998-07-01 | 2000-01-21 | Nok Corp | Reaction product measuring device |
US6656702B1 (en) | 1998-07-03 | 2003-12-02 | Matsushita Electric Industrial Co., Ltd. | Biosensor containing glucose dehydrogenase |
GB2339615B (en) | 1998-07-14 | 2001-02-07 | Cozart Bioscience Ltd | Screening device and method of screening an immunoassay test |
US6521182B1 (en) * | 1998-07-20 | 2003-02-18 | Lifescan, Inc. | Fluidic device for medical diagnostics |
US6261519B1 (en) | 1998-07-20 | 2001-07-17 | Lifescan, Inc. | Medical diagnostic device with enough-sample indicator |
US6162397A (en) | 1998-08-13 | 2000-12-19 | Lifescan, Inc. | Visual blood glucose test strip |
US6096186A (en) | 1998-08-18 | 2000-08-01 | Industrial Scientific Corporation | Method for determining exhaustion of an electrochemical gas sensor |
DE29814997U1 (en) | 1998-08-20 | 1998-12-03 | Lre Technology Partner Gmbh | Test strip measuring system |
US6638716B2 (en) | 1998-08-24 | 2003-10-28 | Therasense, Inc. | Rapid amperometric verification of PCR amplification of DNA |
US6281006B1 (en) | 1998-08-24 | 2001-08-28 | Therasense, Inc. | Electrochemical affinity assay |
US6251260B1 (en) | 1998-08-24 | 2001-06-26 | Therasense, Inc. | Potentiometric sensors for analytic determination |
AU770909B2 (en) | 1998-08-26 | 2004-03-04 | Sensors For Medicine And Science, Inc. | Optical-based sensing devices |
US6087182A (en) | 1998-08-27 | 2000-07-11 | Abbott Laboratories | Reagentless analysis of biological samples |
US5902731A (en) | 1998-09-28 | 1999-05-11 | Lifescan, Inc. | Diagnostics based on tetrazolium compounds |
US6180416B1 (en) * | 1998-09-30 | 2001-01-30 | Cygnus, Inc. | Method and device for predicting physiological values |
JP3537136B2 (en) | 1998-09-30 | 2004-06-14 | シグナス, インコーポレイテッド | Method and apparatus for predicting physiological values |
US6338790B1 (en) | 1998-10-08 | 2002-01-15 | Therasense, Inc. | Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator |
US6591125B1 (en) | 2000-06-27 | 2003-07-08 | Therasense, Inc. | Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator |
US6136610A (en) | 1998-11-23 | 2000-10-24 | Praxsys Biosystems, Inc. | Method and apparatus for performing a lateral flow assay |
US6126609A (en) | 1998-11-23 | 2000-10-03 | Keith & Rumph Inventors, Inc. | Apparatus for taking blood samples from a patient |
GB9825992D0 (en) | 1998-11-28 | 1999-01-20 | Moorlodge Biotech Ventures Lim | Electrochemical sensor |
US6377894B1 (en) | 1998-11-30 | 2002-04-23 | Abbott Laboratories | Analyte test instrument having improved calibration and communication processes |
US6128519A (en) | 1998-12-16 | 2000-10-03 | Pepex Biomedical, Llc | System and method for measuring a bioanalyte such as lactate |
EP1010894B1 (en) | 1998-12-19 | 2004-03-03 | GARDENA Kress + Kastner GmbH | Pond insert with pump |
US6203952B1 (en) | 1999-01-14 | 2001-03-20 | 3M Innovative Properties Company | Imaged article on polymeric substrate |
US6344490B1 (en) * | 1999-01-22 | 2002-02-05 | Exxon Research And Engineering Company | Removable filter for slurry hydrocarbon synthesis process |
DE59900131D1 (en) | 1999-01-23 | 2001-07-26 | Ident Gmbh X | RFID transponder with printable surface |
US6565738B1 (en) | 1999-01-28 | 2003-05-20 | Abbott Laboratories | Diagnostic test for the measurement of analyte in abiological fluid |
US6475372B1 (en) | 2000-02-02 | 2002-11-05 | Lifescan, Inc. | Electrochemical methods and devices for use in the determination of hematocrit corrected analyte concentrations |
US6197040B1 (en) | 1999-02-23 | 2001-03-06 | Lifescan, Inc. | Lancing device having a releasable connector |
US6045567A (en) | 1999-02-23 | 2000-04-04 | Lifescan Inc. | Lancing device causing reduced pain |
GB2347746A (en) | 1999-03-05 | 2000-09-13 | Azur Env Ltd | Detecting analytes, particularly nucleic acids, in a sample |
US6333019B1 (en) | 1999-04-29 | 2001-12-25 | Marc-Olivier Coppens | Method for operating a chemical and/or physical process by means of a hierarchical fluid injection system |
US6150124A (en) | 1999-05-20 | 2000-11-21 | Umm Electronics, Inc. | Method for passively determining the application of a sample fluid on an analyte strip |
US6258229B1 (en) | 1999-06-02 | 2001-07-10 | Handani Winarta | Disposable sub-microliter volume sensor and method of making |
US6287451B1 (en) | 1999-06-02 | 2001-09-11 | Handani Winarta | Disposable sensor and method of making |
US6193873B1 (en) * | 1999-06-15 | 2001-02-27 | Lifescan, Inc. | Sample detection to initiate timing of an electrochemical assay |
EP2322645A1 (en) | 1999-06-18 | 2011-05-18 | Abbott Diabetes Care Inc. | Mass transport limited in vivo analyte sensor |
US6514769B2 (en) * | 1999-07-29 | 2003-02-04 | Jin Po Lee | Multiple analyte assay device with sample integrity monitoring system |
CA2305922C (en) | 1999-08-02 | 2005-09-20 | Bayer Corporation | Improved electrochemical sensor design |
DE19936693A1 (en) | 1999-08-04 | 2001-02-08 | Lre Technology Partner Gmbh | Instrument for the measurement of blood sugar concentrations has a test field with electrodes for the test strip and a circuit for measurement/evaluation of the current strength for display |
US6352633B1 (en) | 1999-08-31 | 2002-03-05 | Spectrumedix Corporation | Automated parallel capillary electrophoresis system with hydrodynamic sample injection |
EP1130390A1 (en) | 1999-09-13 | 2001-09-05 | Matsushita Electric Industrial Co., Ltd. | Process for producing lipid-modified enzyme and biosensor |
US6662439B1 (en) | 1999-10-04 | 2003-12-16 | Roche Diagnostics Corporation | Laser defined features for patterned laminates and electrodes |
US7276146B2 (en) | 2001-11-16 | 2007-10-02 | Roche Diagnostics Operations, Inc. | Electrodes, methods, apparatuses comprising micro-electrode arrays |
US6645359B1 (en) | 2000-10-06 | 2003-11-11 | Roche Diagnostics Corporation | Biosensor |
ATE313790T1 (en) | 1999-10-05 | 2006-01-15 | Matsushita Electric Ind Co Ltd | GLUCOSE SENSOR |
US6136549A (en) | 1999-10-15 | 2000-10-24 | Feistel; Christopher C. | systems and methods for performing magnetic chromatography assays |
US6283982B1 (en) | 1999-10-19 | 2001-09-04 | Facet Technologies, Inc. | Lancing device and method of sample collection |
US6218571B1 (en) | 1999-10-27 | 2001-04-17 | Lifescan, Inc. | 8-(anilino)-1-naphthalenesulfonate analogs |
US6616819B1 (en) | 1999-11-04 | 2003-09-09 | Therasense, Inc. | Small volume in vitro analyte sensor and methods |
US6923894B2 (en) | 1999-11-11 | 2005-08-02 | Apex Biotechnology Corporation | Biosensor with multiple sampling ways |
CN100347537C (en) | 1999-11-15 | 2007-11-07 | 松下电器产业株式会社 | Biosensor, method of forming thin-film electrode, and method and apparatus for quantitative determination |
WO2001036660A2 (en) | 1999-11-15 | 2001-05-25 | Therasense, Inc. | Transition metal complexes attached to a polymer via a flexible chain |
EP1235068B1 (en) | 1999-11-15 | 2006-01-25 | ARKRAY, Inc. | Biosensor |
CN1162699C (en) | 1999-11-16 | 2004-08-18 | 松下电器产业株式会社 | Biosensor |
CA2356364C (en) * | 1999-11-22 | 2003-12-09 | Matsushita Electric Industrial Co., Ltd. | Cholesterol sensor and method for determining cholesterol |
JP4050434B2 (en) | 1999-11-29 | 2008-02-20 | 松下電器産業株式会社 | Sample discrimination method |
JP2001159618A (en) * | 1999-12-03 | 2001-06-12 | Matsushita Electric Ind Co Ltd | Biosensor |
US6413395B1 (en) | 1999-12-16 | 2002-07-02 | Roche Diagnostics Corporation | Biosensor apparatus |
US6316264B1 (en) | 1999-12-17 | 2001-11-13 | Bayer Corporation | Test strip for the assay of an analyte in a liquid sample |
US6541216B1 (en) | 1999-12-22 | 2003-04-01 | Roche Diagnostics Corporation | Amperometric biosensor test strip |
US6627057B1 (en) | 1999-12-23 | 2003-09-30 | Roche Diagnostic Corporation | Microsphere containing sensor |
ES2238254T3 (en) | 1999-12-27 | 2005-09-01 | Matsushita Electric Industrial Co., Ltd. | BIOSENSOR |
JP2001183330A (en) | 1999-12-27 | 2001-07-06 | Matsushita Electric Ind Co Ltd | Biosensor |
JP3982133B2 (en) | 2000-01-25 | 2007-09-26 | 松下電器産業株式会社 | Measuring device using biosensor and biosensor and dedicated standard solution used therefor |
US6716577B1 (en) | 2000-02-02 | 2004-04-06 | Lifescan, Inc. | Electrochemical test strip for use in analyte determination |
US6485923B1 (en) | 2000-02-02 | 2002-11-26 | Lifescan, Inc. | Reagent test strip for analyte determination having hemolyzing agent |
US7147825B2 (en) | 2000-02-18 | 2006-12-12 | Matsushita Electric Industrial Co., Ltd. | Measuring system |
CN1164946C (en) | 2000-02-18 | 2004-09-01 | 松下电器产业株式会社 | Measuring system |
EP1172653A4 (en) | 2000-02-18 | 2003-07-16 | Matsushita Electric Ind Co Ltd | Inspection chip for sensor measuring instrument |
US6538735B1 (en) | 2000-02-25 | 2003-03-25 | Packard Instrument Company | Method and apparatus for producing and measuring light and for determining the amounts of analytes in microplate wells |
US6706159B2 (en) | 2000-03-02 | 2004-03-16 | Diabetes Diagnostics | Combined lancet and electrochemical analyte-testing apparatus |
US6733655B1 (en) | 2000-03-08 | 2004-05-11 | Oliver W. H. Davies | Measurement of substances in liquids |
JP3985417B2 (en) | 2000-03-08 | 2007-10-03 | 松下電器産業株式会社 | Biosensor and manufacturing method thereof |
CA2403579A1 (en) | 2000-03-22 | 2001-09-27 | All Medicus Co., Ltd. | Electrochemical biosensor test strip with recognition electrode and readout meter using this test strip |
KR100340173B1 (en) | 2000-03-22 | 2002-06-12 | 이동준 | Electrochemical Biosensor Readout Meter |
DE10014724A1 (en) | 2000-03-24 | 2001-09-27 | Endress Hauser Gmbh Co | Liquid level and density monitoring method employed in food, chemical industry, involves evaluating vibration of vibrating rods arranged immersed in liquid at two different modes and recognizing mass change in rods |
US6612111B1 (en) | 2000-03-27 | 2003-09-02 | Lifescan, Inc. | Method and device for sampling and analyzing interstitial fluid and whole blood samples |
US6571651B1 (en) | 2000-03-27 | 2003-06-03 | Lifescan, Inc. | Method of preventing short sampling of a capillary or wicking fill device |
US20020092612A1 (en) | 2000-03-28 | 2002-07-18 | Davies Oliver William Hardwicke | Rapid response glucose sensor |
ATE311472T1 (en) | 2000-03-28 | 2005-12-15 | Diabetes Diagnostics Inc | CONTINUOUS PROCESS FOR PRODUCING DISPOSABLE ELECTROCHEMICAL SENSORS |
IL151262A0 (en) | 2000-03-28 | 2003-04-10 | Lifescan Inc | Reagents and methods for detecting a reduced cofactor |
KR20030014375A (en) | 2000-03-28 | 2003-02-17 | 다이어베티스 다이어그노스틱스, 인크. | Rapid response glucose sensor |
US6911131B2 (en) | 2000-03-29 | 2005-06-28 | Matsushita Electric Industrial Co., Ltd. | Biosensor |
JP2001281197A (en) | 2000-03-30 | 2001-10-10 | Matsushita Electric Ind Co Ltd | Biosensor measuring apparatus |
US6488827B1 (en) | 2000-03-31 | 2002-12-03 | Lifescan, Inc. | Capillary flow control in a medical diagnostic device |
CN1191475C (en) | 2000-03-31 | 2005-03-02 | 生命扫描有限公司 | Electrically-conductive patterns monitoring filling of medical devices |
US6858433B1 (en) | 2000-04-03 | 2005-02-22 | Roche Diagnostics Operations, Inc. | Biosensor electromagnetic noise cancellation |
US6623501B2 (en) | 2000-04-05 | 2003-09-23 | Therasense, Inc. | Reusable ceramic skin-piercing device |
AU2001252973A1 (en) | 2000-04-17 | 2001-10-30 | Purdue Research Foundation | Biosensor and related method |
US6413213B1 (en) | 2000-04-18 | 2002-07-02 | Roche Diagnostics Corporation | Subscription based monitoring system and method |
JP4061816B2 (en) | 2000-04-27 | 2008-03-19 | 松下電器産業株式会社 | Biosensor |
JP4562854B2 (en) | 2000-05-08 | 2010-10-13 | パナソニック株式会社 | Chromatographic measurement method |
IT1314759B1 (en) | 2000-05-08 | 2003-01-03 | Menarini Farma Ind | INSTRUMENTATION FOR MEASUREMENT AND CONTROL OF THE CONTENT OF GLUCOSIOLACTATE OR OTHER METABOLITES IN BIOLOGICAL FLUIDS |
WO2001088524A1 (en) | 2000-05-12 | 2001-11-22 | Therasense, Inc. | Electrodes with multilayer membranes and methods of using and making the electrodes |
EP1156302B1 (en) | 2000-05-15 | 2004-09-29 | Krohne Messtechnik Gmbh & Co. Kg | Level measuring device |
US6557427B2 (en) * | 2000-05-24 | 2003-05-06 | Micronics, Inc. | Capillaries for fluid movement within microfluidic channels |
KR100505803B1 (en) | 2000-05-26 | 2005-08-04 | 마츠시타 덴끼 산교 가부시키가이샤 | Biosensor |
EP1202060B1 (en) | 2000-05-29 | 2005-07-13 | Matsushita Electric Industrial Co., Ltd. | Biosensor and method for its preparation |
WO2001092886A1 (en) | 2000-06-01 | 2001-12-06 | Matsushita Electric Industrial Co., Ltd. | Biosensor and blood component analyzing method |
TW548095B (en) * | 2000-06-01 | 2003-08-21 | Chih-Hui Lee | Electrochemical electrode test piece and method for producing the same |
WO2002000112A2 (en) | 2000-06-26 | 2002-01-03 | Boston Medical Technologies, Inc. | Glucose metering system |
KR100513216B1 (en) | 2000-06-28 | 2005-09-07 | 마츠시타 덴끼 산교 가부시키가이샤 | Biosensor |
DE10032775B4 (en) * | 2000-07-06 | 2007-06-14 | Endress + Hauser Gmbh + Co. Kg | Device for determining and / or monitoring the fill level of a product in a container |
US6561989B2 (en) * | 2000-07-10 | 2003-05-13 | Bayer Healthcare, Llc | Thin lance and test sensor having same |
US6444115B1 (en) | 2000-07-14 | 2002-09-03 | Lifescan, Inc. | Electrochemical method for measuring chemical reaction rates |
GB0017737D0 (en) | 2000-07-20 | 2000-09-06 | Hypoguard Limited | Test device |
GB2365123A (en) | 2000-07-20 | 2002-02-13 | Hypoguard Ltd | Test strip |
US6833110B2 (en) | 2000-07-20 | 2004-12-21 | Hypoguard Limited | Test member |
US6885196B2 (en) * | 2000-07-24 | 2005-04-26 | Matsushita Electric Industrial Co., Ltd. | Biosensor |
AU7197501A (en) | 2000-07-31 | 2002-02-13 | Lifescan Inc | Method and apparatus for detecting the presence of a fluid on a test strip |
DE60119133T2 (en) | 2000-07-31 | 2007-01-25 | Matsushita Electric Industrial Co., Ltd., Kadoma | BIOSENSOR |
CN1180259C (en) | 2000-07-31 | 2004-12-15 | 松下电器产业株式会社 | Biosensor |
GB0019694D0 (en) | 2000-08-11 | 2000-09-27 | Cambridge Sensors Ltd | Electrochemical strip test for small volumes |
JP3913454B2 (en) | 2000-08-29 | 2007-05-09 | 株式会社リガク | Measuring method of surface leakage current of sample |
US6420128B1 (en) | 2000-09-12 | 2002-07-16 | Lifescan, Inc. | Test strips for detecting the presence of a reduced cofactor in a sample and method for using the same |
US6555061B1 (en) | 2000-10-05 | 2003-04-29 | Lifescan, Inc. | Multi-layer reagent test strip |
US6540890B1 (en) | 2000-11-01 | 2003-04-01 | Roche Diagnostics Corporation | Biosensor |
EP2096437B1 (en) | 2000-11-30 | 2014-11-19 | Panasonic Healthcare Co., Ltd. | Biosensor for quantifying substrate |
US6967105B2 (en) | 2000-12-02 | 2005-11-22 | Queststar Medical, Inc. | Surface-modified wick for diagnostic test strip |
US6447657B1 (en) | 2000-12-04 | 2002-09-10 | Roche Diagnostics Corporation | Biosensor |
AU783464B2 (en) * | 2000-12-04 | 2005-10-27 | Kubota Corporation | Air diffuser and flushing method thereof |
US6800488B2 (en) | 2000-12-13 | 2004-10-05 | Lifescan, Inc. | Methods of manufacturing reagent test strips |
GB0030929D0 (en) | 2000-12-19 | 2001-01-31 | Inverness Medical Ltd | Analyte measurement |
US6558528B1 (en) | 2000-12-20 | 2003-05-06 | Lifescan, Inc. | Electrochemical test strip cards that include an integral dessicant |
JP4183902B2 (en) | 2000-12-27 | 2008-11-19 | 松下電器産業株式会社 | Biosensor |
US6512986B1 (en) * | 2000-12-30 | 2003-01-28 | Lifescan, Inc. | Method for automated exception-based quality control compliance for point-of-care devices |
US6560471B1 (en) | 2001-01-02 | 2003-05-06 | Therasense, Inc. | Analyte monitoring device and methods of use |
RU2180514C1 (en) | 2001-01-15 | 2002-03-20 | ШМЕЛЕВ Владимир Михайлович | Method for determining glucose concentration in noninvasive way |
CN102012389B (en) * | 2001-01-17 | 2013-04-10 | 爱科来株式会社 | Quantitative analyzing method and quantitative analyzer using sensor |
US6841389B2 (en) | 2001-02-05 | 2005-01-11 | Glucosens, Inc. | Method of determining concentration of glucose in blood |
US6525330B2 (en) * | 2001-02-28 | 2003-02-25 | Home Diagnostics, Inc. | Method of strip insertion detection |
US6562625B2 (en) | 2001-02-28 | 2003-05-13 | Home Diagnostics, Inc. | Distinguishing test types through spectral analysis |
US6541266B2 (en) | 2001-02-28 | 2003-04-01 | Home Diagnostics, Inc. | Method for determining concentration of an analyte in a test strip |
US20020133064A1 (en) | 2001-03-14 | 2002-09-19 | Matsushita Electric Industrial Co., Ltd. | Blood sugar lever measuring device and semiconductor integrated circuit |
US6576102B1 (en) | 2001-03-23 | 2003-06-10 | Virotek, L.L.C. | Electrochemical sensor and method thereof |
US7124095B2 (en) | 2001-03-26 | 2006-10-17 | International Business Machines Corporation | Third party merchandise return method, storage medium and implementing system |
CA2410812C (en) | 2001-03-29 | 2013-01-15 | Inverness Medical Limited | Integrated sample testing meter |
WO2002078512A2 (en) | 2001-04-02 | 2002-10-10 | Therasense, Inc. | Blood glucose tracking apparatus and methods |
EP1281955B1 (en) * | 2001-04-16 | 2013-06-05 | Panasonic Corporation | Biosensor |
DE10123259A1 (en) | 2001-05-12 | 2002-11-21 | Eppendorf Ag | Microfluidic storage and / or dosing component |
JP3621084B2 (en) | 2001-05-15 | 2005-02-16 | 松下電器産業株式会社 | Biosensor |
US6932894B2 (en) | 2001-05-15 | 2005-08-23 | Therasense, Inc. | Biosensor membranes composed of polymers containing heterocyclic nitrogens |
US6491803B1 (en) | 2001-05-18 | 2002-12-10 | Apex Biotechnology Corporation | Test strip and biosensor incorporating with nanometer metal particles |
AU784254B2 (en) * | 2001-05-21 | 2006-03-02 | Bayer Corporation | Improved electrochemical sensor |
JP4213361B2 (en) | 2001-05-22 | 2009-01-21 | パナソニック株式会社 | Biosensor |
US6549796B2 (en) | 2001-05-25 | 2003-04-15 | Lifescan, Inc. | Monitoring analyte concentration using minimally invasive devices |
DE60229476D1 (en) | 2001-05-29 | 2008-12-04 | Matsushita Electric Ind Co Ltd | Biosensor |
US6960287B2 (en) * | 2001-06-11 | 2005-11-01 | Bayer Corporation | Underfill detection system for a test sensor |
US6501976B1 (en) | 2001-06-12 | 2002-12-31 | Lifescan, Inc. | Percutaneous biological fluid sampling and analyte measurement devices and methods |
WO2002103343A1 (en) | 2001-06-14 | 2002-12-27 | Matsushita Electric Industrial Co., Ltd. | Biosensor |
US6576416B2 (en) | 2001-06-19 | 2003-06-10 | Lifescan, Inc. | Analyte measurement device and method of use |
KR100426638B1 (en) * | 2001-07-07 | 2004-04-08 | 주식회사 인포피아 | Glucose strip sensor and glucose measurement method by the strip sensor |
WO2003006404A1 (en) | 2001-07-13 | 2003-01-23 | Exxonmobil Research And Engineering Company | Direct production of high purity fischer-tropsch wax |
US6767441B1 (en) | 2001-07-31 | 2004-07-27 | Nova Biomedical Corporation | Biosensor with peroxidase enzyme |
US20030036202A1 (en) * | 2001-08-01 | 2003-02-20 | Maria Teodorcyzk | Methods and devices for use in analyte concentration determination assays |
JP4283669B2 (en) | 2001-08-01 | 2009-06-24 | アークレイ株式会社 | Analysis tool, analysis device, and method of manufacturing analysis tool |
DE60218695T2 (en) | 2001-08-09 | 2007-11-15 | Matsushita Electric Industrial Co., Ltd., Kadoma | BIOSENSORS AND MEASURING PROCEDURES |
JP3813150B2 (en) | 2001-08-10 | 2006-08-23 | 松下電器産業株式会社 | Biosensor and blood component analysis method using the same |
US6814844B2 (en) | 2001-08-29 | 2004-11-09 | Roche Diagnostics Corporation | Biosensor with code pattern |
US7052591B2 (en) | 2001-09-21 | 2006-05-30 | Therasense, Inc. | Electrodeposition of redox polymers and co-electrodeposition of enzymes by coordinative crosslinking |
JP4264478B2 (en) | 2001-09-28 | 2009-05-20 | アークレイ株式会社 | Measuring tool and concentration measuring device |
US20030108976A1 (en) | 2001-10-09 | 2003-06-12 | Braig James R. | Method and apparatus for improving clinical accuracy of analyte measurements |
US6797150B2 (en) | 2001-10-10 | 2004-09-28 | Lifescan, Inc. | Determination of sample volume adequacy in biosensor devices |
KR100955587B1 (en) | 2001-10-10 | 2010-04-30 | 라이프스캔, 인코포레이티드 | Electrochemical cell |
US7048262B2 (en) | 2001-11-01 | 2006-05-23 | Praxair Technology, Inc. | Method and apparatus for injecting oxygen into fermentation processes |
US6717024B2 (en) | 2001-11-06 | 2004-04-06 | Exxonmobil Research And Engineering Company | Slurry hydrocarbon synthesis with liquid hydroisomerization in the synthesis reactor |
JPWO2003042679A1 (en) | 2001-11-14 | 2005-03-10 | 松下電器産業株式会社 | Biosensor |
EP1452857A4 (en) | 2001-11-14 | 2006-05-24 | Matsushita Electric Ind Co Ltd | Biosensor |
US6872298B2 (en) | 2001-11-20 | 2005-03-29 | Lifescan, Inc. | Determination of sample volume adequacy in biosensor devices |
AU2002346486A1 (en) | 2001-11-21 | 2003-06-10 | James R. Braig | Method for adjusting a blood analyte measurement |
US6749887B1 (en) | 2001-11-28 | 2004-06-15 | Lifescan, Inc. | Solution drying system |
US6689411B2 (en) * | 2001-11-28 | 2004-02-10 | Lifescan, Inc. | Solution striping system |
US6872299B2 (en) | 2001-12-10 | 2005-03-29 | Lifescan, Inc. | Passive sample detection to initiate timing of an assay |
US6856125B2 (en) | 2001-12-12 | 2005-02-15 | Lifescan, Inc. | Biosensor apparatus and method with sample type and volume detection |
WO2003060154A2 (en) | 2002-01-15 | 2003-07-24 | Agamatrix, Inc. | Method and apparatus for processing electrochemical signals |
US6863800B2 (en) | 2002-02-01 | 2005-03-08 | Abbott Laboratories | Electrochemical biosensor strip for analysis of liquid samples |
ES2581779T3 (en) | 2002-02-10 | 2016-09-07 | Agamatrix, Inc | Method for testing electrochemical properties |
DE10206824B4 (en) | 2002-02-18 | 2005-04-28 | Kautex Textron Gmbh & Co Kg | Method for optical level determination in liquid-filled containers |
CA2422206C (en) | 2002-03-15 | 2011-06-14 | Tyco Telecommunications (Us) Inc. | Hybrid raman/erbium-doped fiber amplifier and transmission system with dispersion map |
GB2390602A (en) | 2002-04-02 | 2004-01-14 | Inverness Medical Ltd | Test strip dispenser vial and cassette |
GB2388898B (en) | 2002-04-02 | 2005-10-05 | Inverness Medical Ltd | Integrated sample testing meter |
US6909791B2 (en) | 2002-04-03 | 2005-06-21 | General Phosphorix, Llc | Method of measuring a line edge roughness of micro objects in scanning microscopes |
US7713214B2 (en) | 2002-04-19 | 2010-05-11 | Pelikan Technologies, Inc. | Method and apparatus for a multi-use body fluid sampling device with optical analyte sensing |
US6946299B2 (en) * | 2002-04-25 | 2005-09-20 | Home Diagnostics, Inc. | Systems and methods for blood glucose sensing |
US6743635B2 (en) * | 2002-04-25 | 2004-06-01 | Home Diagnostics, Inc. | System and methods for blood glucose sensing |
US20030143113A2 (en) | 2002-05-09 | 2003-07-31 | Lifescan, Inc. | Physiological sample collection devices and methods of using the same |
CN1467496A (en) * | 2002-06-03 | 2004-01-14 | 松下电器产业株式会社 | Biosensor |
DE20321781U1 (en) | 2002-07-02 | 2009-12-31 | Panasonic Corp., Kadoma | Biosensor, biosensor chip and biosensor device |
US7244264B2 (en) | 2002-12-03 | 2007-07-17 | Roche Diagnostics Operations, Inc. | Dual blade lancing test strip |
US6797039B2 (en) | 2002-12-27 | 2004-09-28 | Dwain F. Spencer | Methods and systems for selectively separating CO2 from a multicomponent gaseous stream |
US7452457B2 (en) * | 2003-06-20 | 2008-11-18 | Roche Diagnostics Operations, Inc. | System and method for analyte measurement using dose sufficiency electrodes |
US7488601B2 (en) * | 2003-06-20 | 2009-02-10 | Roche Diagnostic Operations, Inc. | System and method for determining an abused sensor during analyte measurement |
US7429865B2 (en) | 2005-10-05 | 2008-09-30 | Roche Diagnostics Operations, Inc. | Method and system for error checking an electrochemical sensor |
-
2003
- 2003-10-17 US US10/687,958 patent/US7452457B2/en active Active
-
2004
- 2004-06-18 WO PCT/US2004/019721 patent/WO2005008231A1/en active Search and Examination
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CA2714309A1 (en) | 2005-01-27 |
WO2005008231A1 (en) | 2005-01-27 |
EP1639355A1 (en) | 2006-03-29 |
JP2007524826A (en) | 2007-08-30 |
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