CA2518013C - Pen-type injector with dose dial sleeve - Google Patents
Pen-type injector with dose dial sleeve Download PDFInfo
- Publication number
- CA2518013C CA2518013C CA2518013A CA2518013A CA2518013C CA 2518013 C CA2518013 C CA 2518013C CA 2518013 A CA2518013 A CA 2518013A CA 2518013 A CA2518013 A CA 2518013A CA 2518013 C CA2518013 C CA 2518013C
- Authority
- CA
- Canada
- Prior art keywords
- pen
- type injector
- dose dial
- sleeve
- housing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31525—Dosing
- A61M5/31528—Dosing by means of rotational movements, e.g. screw-thread mechanisms
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
- A61M5/31536—Blocking means to immobilize a selected dose, e.g. to administer equal doses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
- A61M5/31541—Means preventing setting of a dose beyond the amount remaining in the cartridge
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31546—Electrically operated dose setting, e.g. input via touch screen or plus/minus buttons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
- A61M5/31551—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe including axial movement of dose setting member
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/31563—Mechanically operated dose setting member interacting with a displaceable stop member
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31566—Means improving security or handling thereof
- A61M5/31568—Means keeping track of the total dose administered, e.g. since the cartridge was inserted
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31566—Means improving security or handling thereof
- A61M5/3157—Means providing feedback signals when administration is completed
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
- A61M5/31585—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod performed by axially moving actuator, e.g. an injection button
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/3159—Dose expelling manners
- A61M5/31593—Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M2005/2403—Ampoule inserted into the ampoule holder
- A61M2005/2407—Ampoule inserted into the ampoule holder from the rear
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M2005/3125—Details specific display means, e.g. to indicate dose setting
- A61M2005/3126—Specific display means related to dosing
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
- A61M2205/581—Means for facilitating use, e.g. by people with impaired vision by audible feedback
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
- A61M2205/582—Means for facilitating use, e.g. by people with impaired vision by tactile feedback
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/3156—Mechanically operated dose setting member using volume steps only adjustable in discrete intervals, i.e. individually distinct intervals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31566—Means improving security or handling thereof
- A61M5/31573—Accuracy improving means
- A61M5/31575—Accuracy improving means using scaling up or down transmissions, e.g. gearbox
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M5/31578—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
Abstract
The invention relates to a pen-type injector comprising a housing; a piston rod (20) adapted to operate through the housing; a dose dial sleeve (70) located between the housing and the piston rod (20), the dose dial sleeve (70) having a helical thread of first lead; a drive sleeve (30) located between the dose dial sleeve (70) and the piston rod (20), the drive sleeve (30) having a helical groove (38) of second lead. The first lead of the helical thread and the second lead of the helical groove (38) are the same.
Description
PEN-TYPE INJECTOR WITH DOSE DIAL SLEEVE
The present invention relates to pen-type injectors, that is to injectors of the kind that provide for administration by injection of medicinal products from a multidose cartridge.
In particular, the present invention relates to such injectors where a user may set the dose.
Such injectors have application where regular injection by persons without formal medical training occurs. This is increasingly common amongst those having diabetes where self-treatment enables such persons to conduct effective management of their diabetes.
These circumstances set a number of requirements for pen-type injectors of this kind.
The injector must be robust in construction, yet easy to use both in terms of the manipulation of the parts and understanding by a user of its operation. In the case of those with diabetes, many users will be physically infirm and may also have impaired vision. Where the injector is to be disposable rather than reusable, the injector should be cheap to manufacture and easy to dispose of (preferably being suitable for recycling).
It is an advantage of the present invention that an improved pen-type injector is provided.
According to a first aspect of the present invention, a pen-type injector comprises a housing;
a piston rod adapted to operate through the housing;
a dose dial sleeve located between the housing and the piston rod, the dose dial sleeve having a helical thread of first lead;
a drive sleeve located between the dose dial sleeve and the piston rod, the drive sleeve having a helical groove of second lead;
DCA62640PC 2, characterised in that the first lead of the helical thread and the second lead of the helical groove are the same.
Preferably, the piston rod has a first threaded portion at a first end and a second threaded portion at a second end;
an insert or radially inwardly extending flange is located in the housing and through which the first threaded portion of the piston rod may rotate;
the dose dial sleeve being rotatable with respect to the housing and the insert;
the drive sleeve being releasably connected to the dose dial sleeve and connected to the piston rod for rotation with respect thereto along the second threaded portion of the piston rod;
a button is located on the dose dial sleeve and rotatable with respect to the dose dial sleeve; and clutch means are provided which upon depression of the button permit rotation between the dose dial sleeve and the drive sleeve.
Preferably, the injector further comprises a nut which is rotatable with respect to the drive sleeve and axially displaceable but not rotatable with respect to the housing.
More preferably, the drive sleeve is provided at a first end with first and second flanges with an intermediate thread between the first and second flanges, the nut being disposed between the first and second flanges and keyed to the housing by spline means.
Additionally, a first radial stop may be provided on a second face of the nut and a second radial stop may be provided on a first face of the second flange.
Preferably, the first thread of the piston rod is oppositely disposed to the second thread of the piston rod.
Preferably, a second end of the clutch is provided with a plurality of dog teeth adapted to engage with a second end of the dose dial sleeve.
Preferably, the pen-type injector further includes clicker means disposed between the clutch means and spline means provided on the housing.
lore preferably, the clicker means comprises a sleeve provided at a first end with a helically extending arm, a free end of the arm having a toothed member, and at a second end with a plurality of circumferentially directed saw teeth adapted to engage a corresponding plurality of circumferentially saw teeth provided on the clutch means.
Alternatively, the clicker means comprises a sleeve provided at a first end with at least one helically extending arm and at least one spring member, a free end of the arm having a toothed member, and at a second end with a plurality of circumferentially directed saw teeth adapted to engage a corresponding plurality of circumferentially directed saw teeth provided on the clutch means.
Preferably, the main housing is provided with a plurality of maximum dose stops adapted to be abutted by a radial stop provided on the dose dial sleeve. More preferably, at least one of the maximum dose stops comprises a radial stop located between a helical rib and spline means provided at a second end of the housing. Alternatively, at least one of the maximum dose stops comprises a part of a raised window portion provided at a second end of the housing.
Preferably, the dose dial sleeve is provided with a plurality of radially extending members adapted to abut a corresponding plurality of radial stops provided at a second end of the housing.
The invention will now be described with reference to the accompanying drawings, in which:-Figure 1 shows a sectional view of a pen-type injector in accordance with the present invention in a first, cartridge full, position;
Figure 2 shows a sectional view of the pen-type injector of Figure 1 in a second, maximum first dose dialed, position;
Figure 3 shows a sectional view of the pen-type injector of Figure 1 in a third, first maximum first dose dispensed, position;
Figure 4 shows a sectional view of the pen-type injector of Figure 1 in a fourth, final dose dialed, position;
Figure 5 shows a sectional view of the pen-type injector of Figure 1 in a fifth, final dose dispensed, position;
Figure 6 shows a cut-away view of a first detail of the pen-type injector of Figure 1;
Figure 7 shows a partially cut-away view of a second detail of the pen-type injector of Figure 1;
Figure ~ shows a partially cut-away view of a third detail of the pen-type injector of Figure 1;
Figure 9 shows the relative movement of parts of the pen-type injector shown in Figure 1 during dialing up of a dose;
Figure 10 shows the relative movement of parts of the pen-type injector shown in Figure 1 during dialing down of a dose;
Figure 11 shows the relative movement of parts of the pen-type injector shown in Figure 1 during dispensing of a dose;
Figure 12 shows a partially cut-away view of the pen-type injector of Figure 1 in the second, maximum first dose dialed, position;
Figure 13 shows a partially cut-away view of the pen-type injector of Figure 1 in the fourth, final dose dialed, position;
Figure 14 shows a partially cut-away view of the pen-type injector of Figure 1 in one of the first, third or fifth positions;
Figure 15 shows a cut-away view of a first part of a main housing of the pen-type injector of Figure 1; and Figure 16 shows a cut-away view of a second part of the main housing of the pen-type injector of Figure 1.
Deferring first to Figures 1 to 5, there may be seen a pen-type injector in accordance with the present invention in a number of positions.
The pen-type injector comprises a housing having a first cartridge retaining part 2, and second main housing part 4~. A first end of the cartridge retaining means 2 and a second end of the main housing 4. are secured together by retaining features 6. In the illustrated embodiment, the cartridge retaining means 2 is secured within the second end of the main housing 4.
A cartridge ~ from which ~ number of doses of medicinal product may be dispensed is provided in the cartridge retaining part 2. A piston 10 is retained in a first end of the cartridge ~.
A removable cap 12 is releasably retained over a second end of the cartridge retaining part 2. In use the removable cap 12 can be replaced by a user with a suitable needle unit (not shown). A replacable cap 14 is used to cover the cartridge retaining part 2 extending from the main housing 4. Preferably, the outer dimensions of the replaceable cap 14 are similar or identical to the outer dimensions of the main housing 4 to provide the impression of a unitary whole when the replaceable cap 14 is in position covering the cartridge retaining part 2.
In the illustrated embodiment, an insert 16 is provided at a first end of the main housing 4. The insert 16 is secured against rotational or longitudinal motion. The insert 16 is provided with a threaded circular opening 18 extending therethrough.
Alternatively, the insert may be formed integrally with the main housing 4 the form of a radially inwardly directed flange having an internal thread.
A first thread 19 extends from a first end of a piston rod 20. The piston rod 20 is of generally circular section. The first end of the piston rod 20 extends through the threaded opening 1~ in the insert 16. A pressure foot 22 is located at the first end of the piston rod 20. The pressure foot 22 is disposed to abut a second end of the cartridge piston 10. A
second thread 24 extends from a second end of the piston rod 20. In the illustrated embodiment the second thread 24 comprises a series of part threads rather than a complete thread. The illustrated embodiment is easier to manufacture and helps reduce the overall force required for a user to cause medicinal product to be dispensed.
The first thread 19 and the second thread 24 are oppositely disposed. The second end of the piston rod 20 is provided with a receiving recess 26.
A drive sleeve 30 extends about the piston rod 20. The drive sleeve 30 is generally cylindrical. The drive sleeve 30 is provided at a first end with a first radially extending flange 32. A second radially extending flange 34 is provided spaced a distance along the drive sleeve 30 from the first flange 32. 1-~n intermediate thread 36 is provided on an outer part of the drive sleeve 30 extending between the first flange 32 and the second flange 34. A helical groove 38 extends along the internal surface of the drive sleeve 30.
The second thread 24 of the piston rod 20 is adapted to work within the helical groove 38.
A first end of the first flange 32 is adapted to conform to a second side of the insert 16.
A nut 40 is located between the drive sleeve 30 and the main housing 2, disposed between the first flange 32 and the second flange 34. In the illustrated embodiment the nut 40 is a half nut. This assists in the assembly of the injector. The nut 40 has an internal thread matching the intermediate thread 36. The outer surface of the nut 40 and an internal surface of the main housing 4 are keyed together by splines 42 (see Figures 10, 11, 15 and 16) to prevent relative rotation between the nut 40 and the main housing 4, while allowing relative longitudinal movement therebetween.
A shoulder 37 is formed between a second end of the drive sleeve 30 and an extension 38 provided at the second end of the drive sleeve 30. The extension 38 has reduced inner and outer diameters in comparison to the remainder of the drive sleeve 30. A
second end of the extension 38 is provided with a radially outwardly directed flange 39.
A clicker 50 and a clutch 60 are disposed about the drive sleeve 30, between the drive sleeve 30 and a dose dial sleeve 70 (to be described below).
The clicker 50 is located adjacent the second flange 34 of the drive sleeve 30. The clicker 50 is generally cylindrical and is provided at a first end with a flexible helically extending arm 52 (shown most clearly in Figure 6). A free end of the arm 52 is provided with a radially directed toothed member 54. A second end of the clicker 50 is provided with a series of circumferentially directed saw teeth 56 (cf Figure 7). Each saw tooth comprises a longitudinally directed surface and an inclined surface.
In an alternative embodiment (not shown) the clicker means further includes at least one spring member. The at least one spring member assists in the resetting of the clutch means 60 following dispense.
The clutch means 60 is located adj acent the second end of the drive sleeve 30. The clutch means 60 is generally cylindrical and is provided at a first end with a series of circumferentially directed saw teeth 66 (see Figure 7). Each saw tooth comprises a longitudinally directed surface and an inclined surface. Towards the second end 64 of the clutch means 60 there is located a radially inwardly directed flange 62. The flange 62 of the clutch means 60 is disposed between the shoulder 37 of the drive sleeve 30 and the radially outwardly directed flange 39 of the extension 38. The second end of the clutch means 60 is provided with a plurality of dog teeth 65 (Figure 8). The clutch 60 is keyed to the drive sleeve 30 by way of splines (not shown) to prevent relative rotation between the clutch 60 and the drive sleeve 30.
In the illustrated embodiment, the clicker 50 and the clutch 60 each extend approximately half the length of the drive sleeve 30. However, it will be understood that other arrangements regarding the relative lengths of these parts are possible.
The clicker 50 and the clutch means 60 are normally engaged, that is as shown in Figure 7.
A dose dial sleeve 70 is provided outside of the clicker 50 and clutch means 60 and radially inward of the main housing 4. A helical groove 74 is provided about an outer surface of the dose dial sleeve 70.
The main housing 4 is provided with a window 44 through which a part of the outer surface of the dose dial sleeve may be seen. The main housing 4 is further provided with a helical rib 4.6, adapted to be seated in the helical groove 74~ on the outer surface of the dose dial slee~ie 70. The helical rib 4~6 extends for a single sweep of the inner surface of the main housing 4. A first stop 100 is provided between the splines 42 and the helical rib 4.6 (Figure 15). A second stop 102, disposed at an angle of 180° to the first stop 100 is formed by a frame surrounding the window 44 in the main housing 4~ (Figure 16).
Conveniently, a visual indication of the dose that may be dialed, for example reference numerals (not shown), is provided on the outer surface of the dose dial sleeve 70. The window 44 conveniently only allows to be viewed a visual indication of the dose currently dialed.
A second end of the dose dial sleeve 70 is provided with an inwardly directed flange in the form of number of radially extending members 75. A dose dial grip 76 is disposed about an outer surface of the second end of the dose dial sleeve 70. An outer diameter of the dose dial grip 76 preferably corresponds to the outer diameter of the main housing 4.
The dose dial grip 76 is secured to the dose dial sleeve 70 to prevent relative movement therebetween. The dose dial grip 76 is provided with a central opening 78. An annular recess 80 located in the second end of the dose dial grip 76 extends around the opening 78.
A button 82 of generally 'T' section is provided at a second end of the pen-type injector.
A stem 84 of the button 82 may extend through the opening 78 in the dose dial grip 76, through the inner diameter of the extension 38 of the drive sleeve 30 and into the receiving recess 26 of the piston rod 20. The stem 84 is retained for limited axial movement in the drive sleeve 30 and against rotation with respect thereto. A
head 85 of the button 82 is generally circular. A skirt 86 depends from a periphery of the head 85.
The skirt 86 is adapted to be seated in the annular recess 80 of the dose dial grip 76.
~peration of the pen-type injector in accordance with the present invention will now be described. In Figures 9, 10 and 11 arrows A, S, C, D, E, F and G represent the respective movements of the button 82, the dose dial grip 76, the dose dial sleeve 70, the drive sleeve 30, the clutch means 60, the clicker 50 and the nut 40.
To dial a dose (Figure 9) a user rotates the dose dial grip 76 (arrow A). kith the clicker 50 and clutch means 60 engaged, the drive sleeve 30, the clicker 50, the clutch means 60 and the dose dial sleeve 70 rotate with the dose dial grip 76.
Audible and tactile feedback of the dose being dialed is provided by the clicker 50 and the clutch means 60. Torque is transmitted through the saw teeth 56,66 between the clicker 50 and the clutch means 60. The flexible arm 52 deforms and drags the toothed member 54 over the splines 42 to produce a click. Preferably, the splines 42 are disposed such that each click corresponds to a unit dose.
The helical groove 74 on the dose dial sleeve 70 and the helical groove 38 in the drive sleeve 30 have the same lead. This allows the dose dial sleeve 70 (arrow C) to extend from the main housing 4 and the drive sleeve 30 (arrow D) to climb the piston rod 20 at the same rate. At the limit of travel, a radial stop 104 on the dose dial sleeve 70 engages either the first stop 100 or the second stop 102 provided on the main housing 4 to prevent further movement. Rotation of the piston rod 20 is prevented due to the opposing directions of the overhauled and driven threads on the piston rod 20.
The nut 40, keyed to the main housing 4, is advanced along the intermediate thread 36 by the rotation of the drive sleeve 30 (arrow D). When the final dose dispensed position (Figures 4, 5 and 13) is reached, a radial stop 106 formed on a second surface of the nut 40 abuts a radial stop 108 on a first surface of the second flange 34 of the drive sleeve 30, preventing both the nut 40 and the drive sleeve 30 from rotating further.
In an alternative embodiment (not shown) a first surface of the nut 4.0 is provided with a radial stop for abutment with a radial stop provided on a second surface of the first flange 32. This aids location of the nut 40 at the cartridge full position during assembly of the pen-type injector.
Should a user inadvertently dial beyond the desired dosage, the pen-type injector allows the dosage to be dialed down without dispense of medicinal product from the cartridge (Figure 10). The dose dial grip 76 is counter rotated. This causes the system to act in reverse. The flexible arm 52 now acts as a ratchet preventing the clicker from rotating.
The torque transmitted through the clutch means 60 causes the saw teeth 56,66 to ride over one another to create the clicks corresponding to dialed dose reduction.
Preferably the saw teeth 56,66 are so disposed that the circumferential extent of each saw tooth corresponds to a unit dose.
then the desired dose has been dialed, the user may then dispense this dose by depressing the button 82 (Figure 11). This displaces the clutch means 60 axially with respect to the dose dial sleeve 70 causing the dog teeth 65 to disengage.
However the clutch means 60 remains keyed in rotation to the drive sleeve 30. The dose dial sleeve 70 and associated dose dial grip 76 are now free to rotate (guided by the helical rib 46 located in helical groove 74).
The axial movement deforms the flexible arm 52 of the clicker 50 to ensure the saw teeth 56,66 cannot be overhauled during dispense. This prevents the drive sleeve 30 from rotating with respect to the main housing 4 though it is still free to move axially with respect thereto. This deformation is subsequently used to urge the clicker 50, and the clutch 60, back along the drive sleeve 30 to restore the connection between the clutch 60 and the dose dial sleeve 70 when pressure is removed from the button ~2.
The longitudinal axial movement of the drive sleeve 30 causes the piston rod 20 to rotate though the opening 1~ in the insert 16, thereby to advance the piston 10 in the cartridge 8.
~nce the dialed dose has been dispensed, the dose dial sleeve 70 is prevented from further rotation by contact of a plurality of members 110 (Figure 14) extending from the dose dial grip 76 with a corresponding plurality of stops 112 formed in the main housing 4 (Figures 15 and 16). In the illustrated embodiment, the members 110 extend axially from the dose dial grip 76 and have an inclined end surface. The zero dose position is determined by the abutment of one of the axially extending edges of the members 110 with a corresponding stop 112.
The present invention relates to pen-type injectors, that is to injectors of the kind that provide for administration by injection of medicinal products from a multidose cartridge.
In particular, the present invention relates to such injectors where a user may set the dose.
Such injectors have application where regular injection by persons without formal medical training occurs. This is increasingly common amongst those having diabetes where self-treatment enables such persons to conduct effective management of their diabetes.
These circumstances set a number of requirements for pen-type injectors of this kind.
The injector must be robust in construction, yet easy to use both in terms of the manipulation of the parts and understanding by a user of its operation. In the case of those with diabetes, many users will be physically infirm and may also have impaired vision. Where the injector is to be disposable rather than reusable, the injector should be cheap to manufacture and easy to dispose of (preferably being suitable for recycling).
It is an advantage of the present invention that an improved pen-type injector is provided.
According to a first aspect of the present invention, a pen-type injector comprises a housing;
a piston rod adapted to operate through the housing;
a dose dial sleeve located between the housing and the piston rod, the dose dial sleeve having a helical thread of first lead;
a drive sleeve located between the dose dial sleeve and the piston rod, the drive sleeve having a helical groove of second lead;
DCA62640PC 2, characterised in that the first lead of the helical thread and the second lead of the helical groove are the same.
Preferably, the piston rod has a first threaded portion at a first end and a second threaded portion at a second end;
an insert or radially inwardly extending flange is located in the housing and through which the first threaded portion of the piston rod may rotate;
the dose dial sleeve being rotatable with respect to the housing and the insert;
the drive sleeve being releasably connected to the dose dial sleeve and connected to the piston rod for rotation with respect thereto along the second threaded portion of the piston rod;
a button is located on the dose dial sleeve and rotatable with respect to the dose dial sleeve; and clutch means are provided which upon depression of the button permit rotation between the dose dial sleeve and the drive sleeve.
Preferably, the injector further comprises a nut which is rotatable with respect to the drive sleeve and axially displaceable but not rotatable with respect to the housing.
More preferably, the drive sleeve is provided at a first end with first and second flanges with an intermediate thread between the first and second flanges, the nut being disposed between the first and second flanges and keyed to the housing by spline means.
Additionally, a first radial stop may be provided on a second face of the nut and a second radial stop may be provided on a first face of the second flange.
Preferably, the first thread of the piston rod is oppositely disposed to the second thread of the piston rod.
Preferably, a second end of the clutch is provided with a plurality of dog teeth adapted to engage with a second end of the dose dial sleeve.
Preferably, the pen-type injector further includes clicker means disposed between the clutch means and spline means provided on the housing.
lore preferably, the clicker means comprises a sleeve provided at a first end with a helically extending arm, a free end of the arm having a toothed member, and at a second end with a plurality of circumferentially directed saw teeth adapted to engage a corresponding plurality of circumferentially saw teeth provided on the clutch means.
Alternatively, the clicker means comprises a sleeve provided at a first end with at least one helically extending arm and at least one spring member, a free end of the arm having a toothed member, and at a second end with a plurality of circumferentially directed saw teeth adapted to engage a corresponding plurality of circumferentially directed saw teeth provided on the clutch means.
Preferably, the main housing is provided with a plurality of maximum dose stops adapted to be abutted by a radial stop provided on the dose dial sleeve. More preferably, at least one of the maximum dose stops comprises a radial stop located between a helical rib and spline means provided at a second end of the housing. Alternatively, at least one of the maximum dose stops comprises a part of a raised window portion provided at a second end of the housing.
Preferably, the dose dial sleeve is provided with a plurality of radially extending members adapted to abut a corresponding plurality of radial stops provided at a second end of the housing.
The invention will now be described with reference to the accompanying drawings, in which:-Figure 1 shows a sectional view of a pen-type injector in accordance with the present invention in a first, cartridge full, position;
Figure 2 shows a sectional view of the pen-type injector of Figure 1 in a second, maximum first dose dialed, position;
Figure 3 shows a sectional view of the pen-type injector of Figure 1 in a third, first maximum first dose dispensed, position;
Figure 4 shows a sectional view of the pen-type injector of Figure 1 in a fourth, final dose dialed, position;
Figure 5 shows a sectional view of the pen-type injector of Figure 1 in a fifth, final dose dispensed, position;
Figure 6 shows a cut-away view of a first detail of the pen-type injector of Figure 1;
Figure 7 shows a partially cut-away view of a second detail of the pen-type injector of Figure 1;
Figure ~ shows a partially cut-away view of a third detail of the pen-type injector of Figure 1;
Figure 9 shows the relative movement of parts of the pen-type injector shown in Figure 1 during dialing up of a dose;
Figure 10 shows the relative movement of parts of the pen-type injector shown in Figure 1 during dialing down of a dose;
Figure 11 shows the relative movement of parts of the pen-type injector shown in Figure 1 during dispensing of a dose;
Figure 12 shows a partially cut-away view of the pen-type injector of Figure 1 in the second, maximum first dose dialed, position;
Figure 13 shows a partially cut-away view of the pen-type injector of Figure 1 in the fourth, final dose dialed, position;
Figure 14 shows a partially cut-away view of the pen-type injector of Figure 1 in one of the first, third or fifth positions;
Figure 15 shows a cut-away view of a first part of a main housing of the pen-type injector of Figure 1; and Figure 16 shows a cut-away view of a second part of the main housing of the pen-type injector of Figure 1.
Deferring first to Figures 1 to 5, there may be seen a pen-type injector in accordance with the present invention in a number of positions.
The pen-type injector comprises a housing having a first cartridge retaining part 2, and second main housing part 4~. A first end of the cartridge retaining means 2 and a second end of the main housing 4. are secured together by retaining features 6. In the illustrated embodiment, the cartridge retaining means 2 is secured within the second end of the main housing 4.
A cartridge ~ from which ~ number of doses of medicinal product may be dispensed is provided in the cartridge retaining part 2. A piston 10 is retained in a first end of the cartridge ~.
A removable cap 12 is releasably retained over a second end of the cartridge retaining part 2. In use the removable cap 12 can be replaced by a user with a suitable needle unit (not shown). A replacable cap 14 is used to cover the cartridge retaining part 2 extending from the main housing 4. Preferably, the outer dimensions of the replaceable cap 14 are similar or identical to the outer dimensions of the main housing 4 to provide the impression of a unitary whole when the replaceable cap 14 is in position covering the cartridge retaining part 2.
In the illustrated embodiment, an insert 16 is provided at a first end of the main housing 4. The insert 16 is secured against rotational or longitudinal motion. The insert 16 is provided with a threaded circular opening 18 extending therethrough.
Alternatively, the insert may be formed integrally with the main housing 4 the form of a radially inwardly directed flange having an internal thread.
A first thread 19 extends from a first end of a piston rod 20. The piston rod 20 is of generally circular section. The first end of the piston rod 20 extends through the threaded opening 1~ in the insert 16. A pressure foot 22 is located at the first end of the piston rod 20. The pressure foot 22 is disposed to abut a second end of the cartridge piston 10. A
second thread 24 extends from a second end of the piston rod 20. In the illustrated embodiment the second thread 24 comprises a series of part threads rather than a complete thread. The illustrated embodiment is easier to manufacture and helps reduce the overall force required for a user to cause medicinal product to be dispensed.
The first thread 19 and the second thread 24 are oppositely disposed. The second end of the piston rod 20 is provided with a receiving recess 26.
A drive sleeve 30 extends about the piston rod 20. The drive sleeve 30 is generally cylindrical. The drive sleeve 30 is provided at a first end with a first radially extending flange 32. A second radially extending flange 34 is provided spaced a distance along the drive sleeve 30 from the first flange 32. 1-~n intermediate thread 36 is provided on an outer part of the drive sleeve 30 extending between the first flange 32 and the second flange 34. A helical groove 38 extends along the internal surface of the drive sleeve 30.
The second thread 24 of the piston rod 20 is adapted to work within the helical groove 38.
A first end of the first flange 32 is adapted to conform to a second side of the insert 16.
A nut 40 is located between the drive sleeve 30 and the main housing 2, disposed between the first flange 32 and the second flange 34. In the illustrated embodiment the nut 40 is a half nut. This assists in the assembly of the injector. The nut 40 has an internal thread matching the intermediate thread 36. The outer surface of the nut 40 and an internal surface of the main housing 4 are keyed together by splines 42 (see Figures 10, 11, 15 and 16) to prevent relative rotation between the nut 40 and the main housing 4, while allowing relative longitudinal movement therebetween.
A shoulder 37 is formed between a second end of the drive sleeve 30 and an extension 38 provided at the second end of the drive sleeve 30. The extension 38 has reduced inner and outer diameters in comparison to the remainder of the drive sleeve 30. A
second end of the extension 38 is provided with a radially outwardly directed flange 39.
A clicker 50 and a clutch 60 are disposed about the drive sleeve 30, between the drive sleeve 30 and a dose dial sleeve 70 (to be described below).
The clicker 50 is located adjacent the second flange 34 of the drive sleeve 30. The clicker 50 is generally cylindrical and is provided at a first end with a flexible helically extending arm 52 (shown most clearly in Figure 6). A free end of the arm 52 is provided with a radially directed toothed member 54. A second end of the clicker 50 is provided with a series of circumferentially directed saw teeth 56 (cf Figure 7). Each saw tooth comprises a longitudinally directed surface and an inclined surface.
In an alternative embodiment (not shown) the clicker means further includes at least one spring member. The at least one spring member assists in the resetting of the clutch means 60 following dispense.
The clutch means 60 is located adj acent the second end of the drive sleeve 30. The clutch means 60 is generally cylindrical and is provided at a first end with a series of circumferentially directed saw teeth 66 (see Figure 7). Each saw tooth comprises a longitudinally directed surface and an inclined surface. Towards the second end 64 of the clutch means 60 there is located a radially inwardly directed flange 62. The flange 62 of the clutch means 60 is disposed between the shoulder 37 of the drive sleeve 30 and the radially outwardly directed flange 39 of the extension 38. The second end of the clutch means 60 is provided with a plurality of dog teeth 65 (Figure 8). The clutch 60 is keyed to the drive sleeve 30 by way of splines (not shown) to prevent relative rotation between the clutch 60 and the drive sleeve 30.
In the illustrated embodiment, the clicker 50 and the clutch 60 each extend approximately half the length of the drive sleeve 30. However, it will be understood that other arrangements regarding the relative lengths of these parts are possible.
The clicker 50 and the clutch means 60 are normally engaged, that is as shown in Figure 7.
A dose dial sleeve 70 is provided outside of the clicker 50 and clutch means 60 and radially inward of the main housing 4. A helical groove 74 is provided about an outer surface of the dose dial sleeve 70.
The main housing 4 is provided with a window 44 through which a part of the outer surface of the dose dial sleeve may be seen. The main housing 4 is further provided with a helical rib 4.6, adapted to be seated in the helical groove 74~ on the outer surface of the dose dial slee~ie 70. The helical rib 4~6 extends for a single sweep of the inner surface of the main housing 4. A first stop 100 is provided between the splines 42 and the helical rib 4.6 (Figure 15). A second stop 102, disposed at an angle of 180° to the first stop 100 is formed by a frame surrounding the window 44 in the main housing 4~ (Figure 16).
Conveniently, a visual indication of the dose that may be dialed, for example reference numerals (not shown), is provided on the outer surface of the dose dial sleeve 70. The window 44 conveniently only allows to be viewed a visual indication of the dose currently dialed.
A second end of the dose dial sleeve 70 is provided with an inwardly directed flange in the form of number of radially extending members 75. A dose dial grip 76 is disposed about an outer surface of the second end of the dose dial sleeve 70. An outer diameter of the dose dial grip 76 preferably corresponds to the outer diameter of the main housing 4.
The dose dial grip 76 is secured to the dose dial sleeve 70 to prevent relative movement therebetween. The dose dial grip 76 is provided with a central opening 78. An annular recess 80 located in the second end of the dose dial grip 76 extends around the opening 78.
A button 82 of generally 'T' section is provided at a second end of the pen-type injector.
A stem 84 of the button 82 may extend through the opening 78 in the dose dial grip 76, through the inner diameter of the extension 38 of the drive sleeve 30 and into the receiving recess 26 of the piston rod 20. The stem 84 is retained for limited axial movement in the drive sleeve 30 and against rotation with respect thereto. A
head 85 of the button 82 is generally circular. A skirt 86 depends from a periphery of the head 85.
The skirt 86 is adapted to be seated in the annular recess 80 of the dose dial grip 76.
~peration of the pen-type injector in accordance with the present invention will now be described. In Figures 9, 10 and 11 arrows A, S, C, D, E, F and G represent the respective movements of the button 82, the dose dial grip 76, the dose dial sleeve 70, the drive sleeve 30, the clutch means 60, the clicker 50 and the nut 40.
To dial a dose (Figure 9) a user rotates the dose dial grip 76 (arrow A). kith the clicker 50 and clutch means 60 engaged, the drive sleeve 30, the clicker 50, the clutch means 60 and the dose dial sleeve 70 rotate with the dose dial grip 76.
Audible and tactile feedback of the dose being dialed is provided by the clicker 50 and the clutch means 60. Torque is transmitted through the saw teeth 56,66 between the clicker 50 and the clutch means 60. The flexible arm 52 deforms and drags the toothed member 54 over the splines 42 to produce a click. Preferably, the splines 42 are disposed such that each click corresponds to a unit dose.
The helical groove 74 on the dose dial sleeve 70 and the helical groove 38 in the drive sleeve 30 have the same lead. This allows the dose dial sleeve 70 (arrow C) to extend from the main housing 4 and the drive sleeve 30 (arrow D) to climb the piston rod 20 at the same rate. At the limit of travel, a radial stop 104 on the dose dial sleeve 70 engages either the first stop 100 or the second stop 102 provided on the main housing 4 to prevent further movement. Rotation of the piston rod 20 is prevented due to the opposing directions of the overhauled and driven threads on the piston rod 20.
The nut 40, keyed to the main housing 4, is advanced along the intermediate thread 36 by the rotation of the drive sleeve 30 (arrow D). When the final dose dispensed position (Figures 4, 5 and 13) is reached, a radial stop 106 formed on a second surface of the nut 40 abuts a radial stop 108 on a first surface of the second flange 34 of the drive sleeve 30, preventing both the nut 40 and the drive sleeve 30 from rotating further.
In an alternative embodiment (not shown) a first surface of the nut 4.0 is provided with a radial stop for abutment with a radial stop provided on a second surface of the first flange 32. This aids location of the nut 40 at the cartridge full position during assembly of the pen-type injector.
Should a user inadvertently dial beyond the desired dosage, the pen-type injector allows the dosage to be dialed down without dispense of medicinal product from the cartridge (Figure 10). The dose dial grip 76 is counter rotated. This causes the system to act in reverse. The flexible arm 52 now acts as a ratchet preventing the clicker from rotating.
The torque transmitted through the clutch means 60 causes the saw teeth 56,66 to ride over one another to create the clicks corresponding to dialed dose reduction.
Preferably the saw teeth 56,66 are so disposed that the circumferential extent of each saw tooth corresponds to a unit dose.
then the desired dose has been dialed, the user may then dispense this dose by depressing the button 82 (Figure 11). This displaces the clutch means 60 axially with respect to the dose dial sleeve 70 causing the dog teeth 65 to disengage.
However the clutch means 60 remains keyed in rotation to the drive sleeve 30. The dose dial sleeve 70 and associated dose dial grip 76 are now free to rotate (guided by the helical rib 46 located in helical groove 74).
The axial movement deforms the flexible arm 52 of the clicker 50 to ensure the saw teeth 56,66 cannot be overhauled during dispense. This prevents the drive sleeve 30 from rotating with respect to the main housing 4 though it is still free to move axially with respect thereto. This deformation is subsequently used to urge the clicker 50, and the clutch 60, back along the drive sleeve 30 to restore the connection between the clutch 60 and the dose dial sleeve 70 when pressure is removed from the button ~2.
The longitudinal axial movement of the drive sleeve 30 causes the piston rod 20 to rotate though the opening 1~ in the insert 16, thereby to advance the piston 10 in the cartridge 8.
~nce the dialed dose has been dispensed, the dose dial sleeve 70 is prevented from further rotation by contact of a plurality of members 110 (Figure 14) extending from the dose dial grip 76 with a corresponding plurality of stops 112 formed in the main housing 4 (Figures 15 and 16). In the illustrated embodiment, the members 110 extend axially from the dose dial grip 76 and have an inclined end surface. The zero dose position is determined by the abutment of one of the axially extending edges of the members 110 with a corresponding stop 112.
Claims (14)
1. A pen-type injector comprising a housing;
a piston rod adapted to operate through the housing;
a dose dial sleeve located between the housing and the piston rod, the dose dial sleeve having a helical thread of first lead;
a drive sleeve located between the dose dial sleeve and the piston rod, the drive sleeve having a helical groove of second lead;
characterised in that the first lead of the helical thread and the second lead of the helical groove are the same, said dose dial sleeve and said drive sleeve not being mechanically engaged by means of said helical thread/helical groove and said drive sleeve being releasably connected to said dose dial sleeve.
a piston rod adapted to operate through the housing;
a dose dial sleeve located between the housing and the piston rod, the dose dial sleeve having a helical thread of first lead;
a drive sleeve located between the dose dial sleeve and the piston rod, the drive sleeve having a helical groove of second lead;
characterised in that the first lead of the helical thread and the second lead of the helical groove are the same, said dose dial sleeve and said drive sleeve not being mechanically engaged by means of said helical thread/helical groove and said drive sleeve being releasably connected to said dose dial sleeve.
2. A pen-type injector according to claim 1, characterised in that the piston rod has a first threaded portion at a first end and a second threaded portion at a second end;
an insert or radially inwardly extending flange is located in the housing and through which the first threaded portion of the piston rod may rotate;
the dose dial sleeve being rotatable with respect to the housing and the insert;
the drive sleeve being connected to the piston rod for rotation with respect thereto along the second threaded portion of the piston rod;
a button is located on the dose dial sleeve and rotatable with respect to the dose dial sleeve; and clutch means are provided which upon depression of the button permit rotation between the dose dial sleeve and the drive sleeve.
an insert or radially inwardly extending flange is located in the housing and through which the first threaded portion of the piston rod may rotate;
the dose dial sleeve being rotatable with respect to the housing and the insert;
the drive sleeve being connected to the piston rod for rotation with respect thereto along the second threaded portion of the piston rod;
a button is located on the dose dial sleeve and rotatable with respect to the dose dial sleeve; and clutch means are provided which upon depression of the button permit rotation between the dose dial sleeve and the drive sleeve.
3. A pen-type injector according to claim 1 or claim 2, in which the injector further comprises a nut which is rotatable with respect to the drive sleeve and axially displaceable but not rotatable with respect to the housing.
4. A pen-type injector according to claim 3, in which the drive sleeve is provided at a first end with first and second flanges with an intermediate thread between the first and second flanges, the nut being disposed between the first and second flanges and keyed to the housing by spline means.
5. A pen-type injector according to claim 4, in which a first radial stop is provided on a second face of the nut and a second radial stop is provided on a first face of the second flange.
6. A pen-type injector according to any one of claims 2 to 5, in which the first thread of the piston rod is oppositely disposed to the second thread of the piston rod.
7. A pen-type injector according to any one of claims 2 to 6, in which a second end of the clutch is provided with a plurality of dog teeth adapted to engage with a second end of the dose dial sleeve.
8. A pen-type injector according to any one of claims 2 to 7, in which the pen-type injector further includes clicker means disposed between the clutch means and spline means provided on the housing.
9. A pen-type injector according to claim 8, in which the clicker means comprises a sleeve provided at a first end with a helically extending arm, a free end of the arm having a toothed member, and at a second end with a plurality of circumferentially directed saw teeth adapted to engage a corresponding plurality of circumferentially saw teeth provided on the clutch means.
10. A pen-type injector according to claim 8, in which the clicker means comprises a sleeve provided at a first end with at least one helically extending arm and at least one spring member, a free end of the arm having a toothed member, and at a second end with a plurality of circumferentially directed saw teeth adapted to engage a corresponding plurality of circumferentially directed saw teeth provided on the clutch means.
11. A pen-type injector according to any one of claims 1 to 10, in which the main housing is provided with a plurality of maximum dose stops adapted to be abutted by a radial stop provided on the dose dial sleeve.
12. A pen-type injector according to claim 11, in which at least one of the maximum dose stops comprises a radial stop located between a helical rib and spline means provided at a second end of the housing.
13. A pen-type injector according to claim 11, in which at least one of the maximum dose stops comprises a part of a raised window portion provided at a second end of the housing.
14. A pen-type injector according to any one of claims 1 to 13, in which the dose dial sleeve is provided with a plurality of radially extending members adapted to abut a corresponding plurality of radial stops provided at a second end of the housing.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0304822.0A GB0304822D0 (en) | 2003-03-03 | 2003-03-03 | Improvements in and relating to a pen-type injector |
GB0304822.0 | 2003-03-03 | ||
PCT/EP2004/002119 WO2004078241A1 (en) | 2003-03-03 | 2004-03-03 | Pen-type injector with dose dial sleeve |
Publications (2)
Publication Number | Publication Date |
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CA2518013A1 CA2518013A1 (en) | 2004-09-16 |
CA2518013C true CA2518013C (en) | 2011-11-01 |
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Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2518013A Expired - Fee Related CA2518013C (en) | 2003-03-03 | 2004-03-03 | Pen-type injector with dose dial sleeve |
CA2517741A Expired - Fee Related CA2517741C (en) | 2003-03-03 | 2004-03-03 | Drive mechanism for drug delivery device |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2517741A Expired - Fee Related CA2517741C (en) | 2003-03-03 | 2004-03-03 | Drive mechanism for drug delivery device |
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US (30) | US20040267208A1 (en) |
EP (12) | EP2263724B1 (en) |
JP (2) | JP4741463B2 (en) |
KR (1) | KR101095289B1 (en) |
CN (1) | CN100443128C (en) |
AR (1) | AR043459A1 (en) |
AT (4) | ATE497398T1 (en) |
AU (3) | AU2004216830B2 (en) |
BR (1) | BRPI0408064B8 (en) |
CA (2) | CA2518013C (en) |
CY (9) | CY1108189T1 (en) |
DE (7) | DE602004019351D1 (en) |
DK (12) | DK2266648T3 (en) |
EA (1) | EA008566B1 (en) |
ES (11) | ES2413432T3 (en) |
GB (1) | GB0304822D0 (en) |
HK (1) | HK1092082A1 (en) |
HR (1) | HRP20050766B1 (en) |
HU (1) | HUE035666T2 (en) |
IL (1) | IL170480A (en) |
MX (2) | MXPA05009286A (en) |
PL (11) | PL1974761T3 (en) |
PT (10) | PT2263722E (en) |
SI (10) | SI1974761T1 (en) |
TW (2) | TWI340654B (en) |
WO (2) | WO2004078239A1 (en) |
ZA (1) | ZA200506711B (en) |
Families Citing this family (425)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2305634C (en) | 1998-01-30 | 2006-01-03 | Novo Nordisk A/S | An injection syringe |
TW453884B (en) | 1999-09-16 | 2001-09-11 | Novo Nordisk As | Dose setting limiter |
US6663602B2 (en) * | 2000-06-16 | 2003-12-16 | Novo Nordisk A/S | Injection device |
GB0304822D0 (en) | 2003-03-03 | 2003-04-09 | Dca Internat Ltd | Improvements in and relating to a pen-type injector |
GB0304823D0 (en) | 2003-03-03 | 2003-04-09 | Dca Internat Ltd | Improvements in and relating to a pen-type injector |
US9205197B2 (en) * | 2003-03-03 | 2015-12-08 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device dose setting mechanism |
GB0308267D0 (en) | 2003-04-10 | 2003-05-14 | Dca Design Int Ltd | Improvements in and relating to a pen-type injector |
CN100531813C (en) | 2003-08-12 | 2009-08-26 | 伊莱利利公司 | Medication dispensing apparatus with triple screw threads for mechanical advantage |
JP4874233B2 (en) | 2004-03-30 | 2012-02-15 | イーライ リリー アンド カンパニー | Drug delivery device with spring-driven fixation feature enabled by final dose administration |
DK1732628T3 (en) | 2004-03-30 | 2011-10-24 | Lilly Co Eli | Medication dispenser with gear set with opening for a drive element |
JP4922172B2 (en) | 2004-10-04 | 2012-04-25 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | Drive mechanism for drug delivery device |
EP1645301A1 (en) | 2004-10-11 | 2006-04-12 | Novo Nordisk A/S | Injection device |
ATE444090T1 (en) | 2004-10-21 | 2009-10-15 | Novo Nordisk As | SELECTION MECHANISM FOR A ROTARY PIN |
US10737028B2 (en) | 2004-11-22 | 2020-08-11 | Kaleo, Inc. | Devices, systems and methods for medicament delivery |
AU2004325202B2 (en) | 2004-11-22 | 2009-02-19 | Kaleo, Inc. | Devices, systems, and methods for medicament delivery |
US7648483B2 (en) | 2004-11-22 | 2010-01-19 | Intelliject, Inc. | Devices, systems and methods for medicament delivery |
US7947017B2 (en) | 2004-11-22 | 2011-05-24 | Intelliject, Inc. | Devices, systems and methods for medicament delivery |
US11590286B2 (en) | 2004-11-22 | 2023-02-28 | Kaleo, Inc. | Devices, systems and methods for medicament delivery |
DE602005026595D1 (en) | 2004-12-01 | 2011-04-07 | Novo Nordisk As | injection device |
DE102004063645A1 (en) | 2004-12-31 | 2006-07-20 | Tecpharma Licensing Ag | Device for metered administration of a fluid product with decoupling for a container change |
DE102005001159A1 (en) * | 2005-01-10 | 2006-07-20 | Tecpharma Licensing Ag | Dosing device for an injection device with translation |
JP4903160B2 (en) * | 2005-01-18 | 2012-03-28 | ウォックハート アメリカズ インコーポレイテッド | Pen-type drug injection device |
PL2058020T3 (en) | 2005-02-01 | 2013-03-29 | Kaleo Inc | Devices for medicament delivery |
US8231573B2 (en) | 2005-02-01 | 2012-07-31 | Intelliject, Inc. | Medicament delivery device having an electronic circuit system |
US8206360B2 (en) | 2005-02-01 | 2012-06-26 | Intelliject, Inc. | Devices, systems and methods for medicament delivery |
US9022980B2 (en) | 2005-02-01 | 2015-05-05 | Kaleo, Inc. | Medical injector simulation device |
US8257318B2 (en) | 2005-02-11 | 2012-09-04 | Novo Nordisk A/S | Injection device having a rotatable scale drum |
WO2006086983A1 (en) * | 2005-02-17 | 2006-08-24 | Novo Nordisk A/S | A dose setting element for an injection device and having a dose setting limiting mechanism |
DE102005008280B3 (en) † | 2005-02-23 | 2006-07-13 | Tecpharma Licensing Ag | Medicine administering device has medicine transporting elements and a dosing device that is used with a display drum and an activation element to permit the accurate administration of correct medicine amounts |
EP1855744A1 (en) * | 2005-02-28 | 2007-11-21 | Novo Nordisk A/S | A dose setting mechanism for an injection device |
EP1877121B1 (en) * | 2005-04-24 | 2015-09-23 | Novo Nordisk A/S | Injection device |
US20080221530A1 (en) * | 2005-04-24 | 2008-09-11 | Novo Nordisk A/S | Injection Device With A GearBox |
DE102005023824A1 (en) | 2005-05-24 | 2006-12-07 | Tecpharma Licensing Ag | Dosing device for an injection device |
DE102005023854B4 (en) † | 2005-05-24 | 2020-12-17 | Tecpharma Licensing Ag | Dosing device for an injection device |
EP1907031A2 (en) | 2005-05-31 | 2008-04-09 | Novo Nordisk A/S | Injection device with visual end-of-content indication |
JP4994370B2 (en) * | 2005-07-08 | 2012-08-08 | ノボ・ノルデイスク・エー/エス | Injection device |
DE602006020453D1 (en) * | 2005-07-27 | 2011-04-14 | Novo Nordisk As | DOSE MECHANISM FOR AN INJECTION DEVICE FOR LIMITING DOSE SETTING ACCORDING TO REMAINING MEDICINES |
DE602006010396D1 (en) * | 2005-07-27 | 2009-12-24 | Novo Nordisk As | SPRAY DEVICE WITH A DOSE-LIMITING MECHANISM AND AN ADDITIONAL SAFETY MECHANISM |
US7650181B2 (en) | 2005-09-14 | 2010-01-19 | Zoll Medical Corporation | Synchronization of repetitive therapeutic interventions |
GB0524604D0 (en) * | 2005-12-02 | 2006-01-11 | Owen Mumford Ltd | Injection method and apparatus |
DE102005060928A1 (en) * | 2005-12-20 | 2007-06-28 | Tecpharma Licensing Ag | Injection device with axially overlapping metering or display element |
CN101421002B (en) * | 2006-02-09 | 2012-09-26 | 阿德兰斯研究学院有限公司 | Apparatus and methods for delivering fluid and material to a subject |
JP5183499B2 (en) | 2006-03-10 | 2013-04-17 | ノボ・ノルデイスク・エー/エス | Injection device |
JP5062768B2 (en) | 2006-03-10 | 2012-10-31 | ノボ・ノルデイスク・エー/エス | INJECTION DEVICE AND METHOD FOR REPLACING CARTRIDGE OF THE DEVICE |
DE602007004972D1 (en) | 2006-05-16 | 2010-04-08 | Novo Nordisk As | GEARING MECHANISM FOR AN INJECTION DEVICE |
AU2007253481B2 (en) | 2006-05-18 | 2013-01-17 | Novo Nordisk A/S | An injection device with mode locking means |
EP3738626B1 (en) | 2006-09-15 | 2022-08-10 | Ypsomed AG | Injection device comprising an improved delivery element |
EP1923084A1 (en) * | 2006-11-17 | 2008-05-21 | Sanofi-Aventis Deutschland GmbH | Dosing and drive mechanism for drug delivery device |
EP1923085A1 (en) * | 2006-11-17 | 2008-05-21 | Sanofi-Aventis Deutschland GmbH | Dosing and drive mechanism for drug delivery device |
PL2109474T5 (en) | 2007-02-05 | 2019-07-31 | Novo Nordisk A/S | Injection button |
JP5230722B2 (en) | 2007-03-23 | 2013-07-10 | ノボ・ノルデイスク・エー/エス | Injection device with lock nut |
DE102007018696A1 (en) | 2007-04-18 | 2008-10-23 | Sanofi-Aventis Deutschland Gmbh | Injection device for dispensing a medicament |
DE102007019124A1 (en) | 2007-04-23 | 2008-11-06 | Tecpharma Licensing Ag | Reversible metering device for an injection device |
DE102007026083A1 (en) * | 2007-05-25 | 2008-11-27 | Haselmeier S.A.R.L. | injection device |
US8221358B2 (en) * | 2007-11-20 | 2012-07-17 | Warsaw Orthopedic, Inc. | Devices and methods for delivering drug depots to a site beneath the skin |
ES2416728T3 (en) | 2007-12-20 | 2013-08-02 | Novo Nordisk A/S | Injection device for administering a fixed dose of liquid drug |
EP2274029B1 (en) | 2008-05-02 | 2011-11-02 | Sanofi-Aventis Deutschland GmbH | Medication delivery device |
US8647309B2 (en) * | 2008-05-02 | 2014-02-11 | Sanofi-Aventis Deutschland Gmbh | Medication delivery device |
ES2394602T5 (en) * | 2008-05-02 | 2020-11-20 | Sanofi Aventis Deutschland | Medication delivery device |
US8267900B2 (en) | 2008-05-02 | 2012-09-18 | Sanofi-Aventis Deutschland Gmbh | Medication delivery device |
USD994111S1 (en) | 2008-05-12 | 2023-08-01 | Kaleo, Inc. | Medicament delivery device cover |
WO2009150028A1 (en) * | 2008-05-26 | 2009-12-17 | Novo Nordisk A/S | Improved injection device |
ES2398034T3 (en) | 2008-07-09 | 2013-03-13 | Sanofi-Aventis Deutschland Gmbh | Medication delivery device and a method of assembling a medication delivery device |
USRE47614E1 (en) | 2008-10-13 | 2019-09-24 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device and method of manufacturing a drug delivery device |
PT3228320T (en) | 2008-10-17 | 2020-03-26 | Sanofi Aventis Deutschland | Combination of an insulin and a glp-1 agonist |
US20100106132A1 (en) * | 2008-10-29 | 2010-04-29 | Warsaw Orthopedic, Inc. | Drug cartridge for delivering a drug depot comprising superior and inferior covers |
US20100106136A1 (en) * | 2008-10-29 | 2010-04-29 | Warsaw Orthopedic, Inc. | Drug delivery device with sliding cartridge |
US9352137B2 (en) * | 2008-10-29 | 2016-05-31 | Warsaw Orthopedic, Inc. | Drug cartridge for delivering a drug depot comprising a bulking agent and/or cover |
EP2193817A1 (en) * | 2008-12-02 | 2010-06-09 | Sanofi-Aventis Deutschland GmbH | Drive assembly suitable for use in a medication delivery device and medication delivery device |
EP2196232A1 (en) | 2008-12-12 | 2010-06-16 | Sanofi-Aventis Deutschland GmbH | Drive mechanism for a medication delivery device and medication delivery device |
EP2196233A1 (en) | 2008-12-12 | 2010-06-16 | Sanofi-Aventis Deutschland GmbH | Resettable drive mechanism for a medication delivery device and medication delivery device |
EP2201972A1 (en) | 2008-12-23 | 2010-06-30 | Sanofi-Aventis Deutschland GmbH | Fixed dose injection device with resettable drive mechanism |
EP2208503A1 (en) * | 2009-01-20 | 2010-07-21 | Sanofi-Aventis Deutschland GmbH | Drive assembly and medication delivery device |
EP2414006B1 (en) * | 2009-03-30 | 2020-01-08 | Sanofi-Aventis Deutschland GmbH | Drug delivery device with an improved piston rod |
US9555194B2 (en) * | 2009-03-31 | 2017-01-31 | Sanofi-Aventis Deutschalnd Gmbh | Drug delivery device |
CA2756966A1 (en) | 2009-03-31 | 2010-10-07 | Sanofi-Aventis Deutschland Gmbh | Dose button for a drug delivery device and method for manufacturing a dose button |
JP5748738B2 (en) * | 2009-03-31 | 2015-07-15 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | Drug delivery device |
JP5943834B2 (en) | 2009-03-31 | 2016-07-05 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | Attachment method and linkage assembly for a drug delivery device |
EP2415041B1 (en) | 2009-03-31 | 2018-11-21 | Sanofi-Aventis Deutschland GmbH | Method for manufacturing a drug delivery device body using an adhesive and drug delivery device body |
CA2756587A1 (en) * | 2009-03-31 | 2010-10-07 | Sanofi-Aventis Deutschland Gmbh | Medical device having a mechanism with a spring and use of a wave spring or wave washer within a medical device |
CN102448527B (en) | 2009-03-31 | 2015-10-21 | 赛诺菲-安万特德国有限公司 | The cap for brush |
NZ595940A (en) | 2009-04-30 | 2013-07-26 | Sanofi Aventis Deutschland | Axially adjustable connection of piston rod to piston for drive mechanism of a drug delivery device with an interlock means to lock the piston rod to the piston |
US9463283B2 (en) | 2009-06-01 | 2016-10-11 | Sanofi-Aventis Deutschland Gmbh | Dosing mechanism for a drug deliver device |
US8672896B2 (en) * | 2009-06-01 | 2014-03-18 | Sanofi-Aventis Deutschland Gmbh | Inner housing for a drug delivery device |
US9457150B2 (en) | 2009-06-01 | 2016-10-04 | Sanofi-Aventis Deutschland Gmbh | Biasing mechanism for a drug delivery device |
US8585656B2 (en) | 2009-06-01 | 2013-11-19 | Sanofi-Aventis Deutschland Gmbh | Dose setting mechanism for priming a drug delivery device |
US8257319B2 (en) | 2009-06-01 | 2012-09-04 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device inner housing having helical spline |
AU2014218406B2 (en) * | 2009-06-01 | 2016-06-30 | Sanofi-Aventis Deutschland Gmbh | A resettable dose setting mechanism for a drug delivery device |
US9238106B2 (en) | 2009-06-01 | 2016-01-19 | Sanofi-Aventis Deutschland Gmbh | Dose setting mechanism for priming a drug delivery device |
US9199040B2 (en) | 2009-06-01 | 2015-12-01 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device last dose lock-out mechanism |
US10034982B2 (en) * | 2009-06-01 | 2018-07-31 | Sanofi-Aventis Deutschland Gmbh | Spindle for a drug delivery device |
US9345840B2 (en) | 2009-06-01 | 2016-05-24 | Sanofi-Aventis Deutschland Gmbh | Drug delivery dose setting mechanism with variable maximum dose |
US9950116B2 (en) | 2009-06-01 | 2018-04-24 | Sanofi-Aventis Deutschland Gmbh | Dose setting mechanism for priming a drug delivery device |
US9623187B2 (en) | 2009-06-01 | 2017-04-18 | Sanofi-Aventis Deutschland Gmbh | Resettable drug delivery device |
US9125994B2 (en) | 2009-06-01 | 2015-09-08 | Sanofi—Aventis Deutschland GmbH | Drug delivery device with dose dial sleeve rotational stop |
US9108007B2 (en) | 2009-06-01 | 2015-08-18 | Sanofi-Aventis Deutschland Gmbh | Spindle and bearing combination and drug delivery device |
US8974423B2 (en) | 2009-06-01 | 2015-03-10 | Sanofi-Aventis Deutschland Gmbh | Resettable drug delivery device |
US8728043B2 (en) | 2009-06-01 | 2014-05-20 | Sanofi-Aventis Deutschland Gmbh | Drive mechanism for a drug delivery device |
AR076722A1 (en) | 2009-06-02 | 2011-06-29 | Sanofi Aventis Deutschland | SET FOR A DEVICE FOR THE DELIVERY OF PHARMACOS AND DEVICE FOR THE DELIVERY OF PHARMACOS |
PL2445551T3 (en) * | 2009-06-23 | 2020-05-18 | Tecpharma Licensing Ag | Injection device having a dosing mechanism for limiting a dose setting |
EP2266647A1 (en) * | 2009-06-25 | 2010-12-29 | Sanofi-Aventis Deutschland GmbH | Drive mechanism for drug delivery device |
EP2448620A1 (en) * | 2009-06-30 | 2012-05-09 | Sanofi-Aventis Deutschland GmbH | Drive mechanism and drug delivery device |
US10232122B2 (en) | 2009-09-07 | 2019-03-19 | Sanofi-Aventis Deutschland Gmbh | Drive mechanism for drug delivery device |
EP2292286A1 (en) * | 2009-09-07 | 2011-03-09 | Sanofi-Aventis Deutschland GmbH | Drive mechanism for a medication delivery device and medication delivery device |
CA2774587A1 (en) * | 2009-09-30 | 2011-04-07 | Sanofi-Aventis Deutschland Gmbh | Assembly for a drug delivery device |
AR078457A1 (en) * | 2009-09-30 | 2011-11-09 | Sanofi Aventis Deutschland | DRIVING MECHANISM FOR A DRUG DISCHARGE DEVICE |
WO2011039210A1 (en) * | 2009-09-30 | 2011-04-07 | Sanofi-Aventis Deutschland Gmbh | Assembly for a drug delivery device |
WO2011039202A1 (en) * | 2009-09-30 | 2011-04-07 | Sanofi-Aventis Deutschland Gmbh | Drive mechanism for a drug delivery device and reset member for a drive mechanism |
US8968259B2 (en) | 2009-09-30 | 2015-03-03 | Sanofi-Aventis Deutschland Gmbh | Resettable drive mechanism for a drug delivery device |
EP2482884B1 (en) * | 2009-09-30 | 2015-11-04 | Sanofi-Aventis Deutschland GmbH | Drug delivery device and drive member for a drug delivery device |
JP5756470B2 (en) * | 2009-09-30 | 2015-07-29 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | Reconfigurable drive assembly and drug delivery device |
CA2773928A1 (en) | 2009-09-30 | 2011-04-07 | Sanofi-Aventis Deutschland Gmbh | Injection device |
WO2011045385A1 (en) * | 2009-10-16 | 2011-04-21 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device |
GB0918145D0 (en) | 2009-10-16 | 2009-12-02 | Owen Mumford Ltd | Injector apparatus |
EP2493532B1 (en) | 2009-10-30 | 2019-07-10 | Sanofi-Aventis Deutschland GmbH | Drug delivery device |
AU2010314169B2 (en) * | 2009-11-03 | 2014-09-04 | Sanofi-Aventis Deutschland Gmbh | Assembly for a drug delivery device and drug delivery device |
TR201809460T4 (en) | 2009-11-13 | 2018-07-23 | Sanofi Aventis Deutschland | Pharmaceutical composition comprising a GLP-1-agonist, an insulin and methionine. |
JP5973918B2 (en) | 2009-11-13 | 2016-08-23 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | Pharmaceutical composition comprising a GLP-1 agonist and methionine |
WO2011060786A1 (en) * | 2009-11-20 | 2011-05-26 | Moeller Claus Schmidt | Spring actuated dose delivery device |
WO2011060785A1 (en) | 2009-11-20 | 2011-05-26 | Moeller Claus Schmidt | Injection device without a gearing |
US9320854B2 (en) | 2009-12-18 | 2016-04-26 | Sanofi-Aventis Deutschland Gmbh | Dose setting mechanism with maximum dose limited element |
US8939438B2 (en) | 2010-01-08 | 2015-01-27 | Lee Spring Company Llc | Plastic spring and method and apparatus for making the same |
JP5872490B2 (en) * | 2010-02-18 | 2016-03-01 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | Clutch mechanism |
WO2011101379A1 (en) | 2010-02-18 | 2011-08-25 | Sanofi-Aventis Deutschland Gmbh | Auto-injector |
CA2798173A1 (en) | 2010-05-04 | 2011-11-10 | Sanofi-Aventis Deutschland Gmbh | Drive mechanism with a low friction coating for a drug delivery device |
AU2011202239C1 (en) * | 2010-05-19 | 2017-03-16 | Sanofi | Long-acting formulations of insulins |
CA2801636A1 (en) | 2010-06-11 | 2011-12-15 | Sanofi-Aventis Deutschland Gmbh | Drive assembly, drive component and drug delivery device |
CA3195444A1 (en) * | 2010-06-18 | 2011-12-18 | Becton, Dickinson And Company | Adjustable plunger dose stop |
JP6165055B2 (en) * | 2010-06-28 | 2017-07-19 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | Automatic syringe |
EP2399635A1 (en) | 2010-06-28 | 2011-12-28 | Sanofi-Aventis Deutschland GmbH | Auto-injector |
EP2600922B2 (en) | 2010-08-06 | 2022-07-20 | Sanofi-Aventis Deutschland GmbH | Cartridge holder and method for assembling a cartridge unit for a drug delivery device |
JP6199186B2 (en) | 2010-08-30 | 2017-09-20 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | Use of AVE0010 for the manufacture of a medicament for the treatment of type 2 diabetes |
US8864721B2 (en) | 2010-09-24 | 2014-10-21 | Eli Lilly And Company | Gearing mechanism for a dose delivery device |
EP2438940A1 (en) * | 2010-10-08 | 2012-04-11 | Sanofi-Aventis Deutschland GmbH | Auto injector with a torsion spring |
EP2627379B1 (en) | 2010-10-13 | 2019-05-01 | Sanofi-Aventis Deutschland GmbH | Drug delivery device with a dose setting mechanism and method of using same |
WO2012049139A1 (en) * | 2010-10-13 | 2012-04-19 | Sanofi-Aventis Deutschland Gmbh | Dose setting mechanism and method of setting a dose |
WO2012049141A1 (en) | 2010-10-13 | 2012-04-19 | Sanofi-Aventis Deutschland Gmbh | Dose setting mechanism and method of using same |
CA2812754A1 (en) | 2010-10-13 | 2012-04-19 | Sanofi-Aventis Deutschland Gmbh | Dose setting mechanism and method of setting a dose |
CN103153372B (en) | 2010-10-13 | 2015-11-25 | 赛诺菲-安万特德国有限公司 | The dosing mechanism of setting dosage and method |
AR083380A1 (en) * | 2010-10-13 | 2013-02-21 | Sanofi Aventis Deutschland | MECHANISM OF DOSE ESTABLISHMENT AND METHOD TO USE THE SAME |
AU2011315628B2 (en) * | 2010-10-13 | 2015-05-07 | Sanofi-Aventis Deutschland Gmbh | Dose setting mechanism |
DK2654858T3 (en) * | 2010-12-21 | 2017-09-25 | Sanofi Aventis Deutschland | INJECTION DEVICE WITH DOSAGE SETTING MECHANISM WITH MAXIMUM DOSAGE STOP |
EP2468330A1 (en) | 2010-12-21 | 2012-06-27 | Sanofi-Aventis Deutschland GmbH | Auto-injector |
EP2468333A1 (en) | 2010-12-21 | 2012-06-27 | Sanofi-Aventis Deutschland GmbH | Auto-injector |
USRE48593E1 (en) | 2010-12-21 | 2021-06-15 | Sanofi-Aventis Deutschland Gmbh | Auto-injector |
US8627816B2 (en) | 2011-02-28 | 2014-01-14 | Intelliject, Inc. | Medicament delivery device for administration of opioid antagonists including formulations for naloxone |
US9173999B2 (en) | 2011-01-26 | 2015-11-03 | Kaleo, Inc. | Devices and methods for delivering medicaments from a multi-chamber container |
US8939943B2 (en) | 2011-01-26 | 2015-01-27 | Kaleo, Inc. | Medicament delivery device for administration of opioid antagonists including formulations for naloxone |
DK2673020T3 (en) * | 2011-02-09 | 2017-11-20 | Sanofi Aventis Deutschland | PEN INJECTION DEVICE FOR TWO PHARMACEUTICALS WITH MICROR RESERVES CONTAINING SECONDARY EMERGENCY MEDICINE |
EP4035712A1 (en) | 2011-03-16 | 2022-08-03 | Becton, Dickinson and Company | Multiple use disposable injection pen |
US11577029B2 (en) | 2012-03-15 | 2023-02-14 | Becton, Dickinson And Company | Multiple use disposable injection pen |
EP2689359B1 (en) | 2011-03-24 | 2020-11-25 | Sanofi-Aventis Deutschland GmbH | Device and method for detecting an actuation action performable with a medical device |
AR086257A1 (en) | 2011-05-06 | 2013-11-27 | Sanofi Aventis Deutschland | FARMACOS ADMINISTRATION DEVICE AND CARTRIDGE SUPPORT FOR A FARMACOS ADMINISTRATION DEVICE |
US9283325B2 (en) * | 2011-05-12 | 2016-03-15 | Shl Group Ab | Medicament delivery device with dose re-setting |
US9821032B2 (en) | 2011-05-13 | 2017-11-21 | Sanofi-Aventis Deutschland Gmbh | Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin |
EP2720738B1 (en) * | 2011-06-17 | 2016-01-20 | Sanofi-Aventis Deutschland GmbH | Cartridge holder assembly for drug delivery devices |
CN103702699B (en) | 2011-07-07 | 2016-08-17 | 诺沃—诺迪斯克有限公司 | There is additional dosage capture and the drug delivery injection pen of display module |
AR087693A1 (en) | 2011-08-29 | 2014-04-09 | Sanofi Aventis Deutschland | PHARMACEUTICAL COMBINATION FOR USE IN GLUCEMIC CONTROL IN PATIENTS WITH TYPE 2 DIABETES |
TWI559929B (en) | 2011-09-01 | 2016-12-01 | Sanofi Aventis Deutschland | Pharmaceutical composition for use in the treatment of a neurodegenerative disease |
EP2753387B1 (en) | 2011-09-08 | 2018-05-30 | Sanofi-Aventis Deutschland GmbH | Method and monitoring device for monitoring operation of a drug delivery device |
CA2848181A1 (en) | 2011-09-29 | 2013-04-04 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device and method for a drug delivery device |
US20130085452A1 (en) * | 2011-09-30 | 2013-04-04 | Becton Dickinson France, S.A.S. | Syringe Assembly Having a Rotatably Advanceable Plunger Rod |
KR20130058350A (en) * | 2011-11-25 | 2013-06-04 | 삼성전자주식회사 | Light emitting diode for automobile lamp |
JP6069351B2 (en) | 2011-12-29 | 2017-02-01 | ノボ・ノルデイスク・エー/エス | Torsion spring type automatic syringe with dial-up / dial-down administration mechanism |
US9751056B2 (en) | 2012-01-23 | 2017-09-05 | Merit Medical Systems, Inc. | Mixing syringe |
US8834449B2 (en) | 2012-01-23 | 2014-09-16 | Ikomed Technologies, Inc. | Mixing syringe |
EP3295979B1 (en) | 2012-02-13 | 2020-06-03 | Sanofi-Aventis Deutschland GmbH | Monitoring device for monitoring operation of a drug delivery device |
WO2013127876A1 (en) | 2012-02-29 | 2013-09-06 | Tecpharma Licensing Ag | Injection device with improved piston rod drive |
US9295782B2 (en) | 2012-03-15 | 2016-03-29 | Becton, Dickinson And Company | Multiple use disposable injection pen |
US9033912B2 (en) | 2012-03-28 | 2015-05-19 | Warsaw Orthopedic, Inc. | Drug delivery system |
AU2013245106B2 (en) | 2012-04-05 | 2017-07-27 | Sanofi-Aventis Deutschland Gmbh | Pen -type injector with window element |
EP2833946B1 (en) | 2012-04-05 | 2017-10-04 | Sanofi-Aventis Deutschland GmbH | Drive mechanism for a drug injection device comprising adhesive to block drive at end of device life to prevent reuse |
WO2013149769A1 (en) | 2012-04-05 | 2013-10-10 | Tecpharma Licensing Ag | Injection device with improved piston rod drive |
PL2836259T3 (en) | 2012-04-11 | 2016-11-30 | Cartridge holder and pen-type injector | |
CN104203316A (en) | 2012-04-19 | 2014-12-10 | 赛诺菲-安万特德国有限公司 | Assembly for a drug delivery device and drug delivery device |
CH706567A2 (en) * | 2012-05-16 | 2013-11-29 | Tecpharma Licensing Ag | Improved device to set a dose a limiting mechanism for an apparatus for administering a product. |
US9522235B2 (en) | 2012-05-22 | 2016-12-20 | Kaleo, Inc. | Devices and methods for delivering medicaments from a multi-chamber container |
WO2013178600A1 (en) | 2012-05-30 | 2013-12-05 | Sanofi-Aventis Deutschland Gmbh | Bearing for a piston rod body for a drug delivery device, a piston rod arrangement and a piston rod body |
US20150165122A1 (en) | 2012-08-08 | 2015-06-18 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device with tamper-evident closure |
US20150209522A1 (en) | 2012-08-20 | 2015-07-30 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device and method for detecting contact between piston rod and cartridge bung via vibration excitation and monitoring |
JP6301334B2 (en) | 2012-08-20 | 2018-03-28 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | Drug delivery device and method for detecting contact |
US10272204B2 (en) | 2012-08-20 | 2019-04-30 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device and method for electrically detecting contact between piston rod and cartridge bung |
ES2941078T3 (en) | 2012-08-31 | 2023-05-16 | Sanofi Aventis Deutschland | drug delivery device |
KR102166894B1 (en) | 2012-08-31 | 2020-10-16 | 사노피-아벤티스 도이칠란트 게엠베하 | Drug delivery device |
WO2014040929A1 (en) | 2012-09-11 | 2014-03-20 | Sanofi-Aventis Deutschland Gmbh | Drive mechanism for a drug delivery device and drug delivery device |
CA2808738C (en) * | 2012-09-26 | 2014-03-18 | Gadlight, Inc | Portable medicine injection device and metering system |
EP2928526B1 (en) | 2012-12-10 | 2023-10-25 | Merck Sharp & Dohme LLC | Medication injector with near-empty alert |
TWI653069B (en) * | 2013-03-11 | 2019-03-11 | 德商賽諾菲阿凡提斯德意志有限公司 | "piston rod and drug delivery device comprising the piston rod" |
EP2968783B1 (en) | 2013-03-13 | 2021-04-21 | Sanofi-Aventis Deutschland GmbH | Assembly for a drug delivery device comprising a feedback feature |
DK2968786T3 (en) | 2013-03-13 | 2020-12-14 | Sanofi Aventis Deutschland | MEDICINE DELIVERY DEVICE WITH A FEEDBACK FUNCTION |
DK2983697T3 (en) | 2013-04-03 | 2019-02-25 | Sanofi Sa | TREATMENT OF DIABETES MELLITUS WITH LONG-EFFECTIVE FORMULATIONS OF INSULIN |
DK2983735T3 (en) * | 2013-04-10 | 2021-03-01 | Sanofi Sa | DRIVE MECHANISM FOR A MEDICINE ADMINISTRATIVE DEVICE |
JP6404323B2 (en) | 2013-04-10 | 2018-10-10 | サノフイSanofi | Injection device |
WO2014166924A1 (en) | 2013-04-10 | 2014-10-16 | Sanofi | Injection device |
DK2983743T3 (en) * | 2013-04-10 | 2019-08-05 | Sanofi Sa | DRIVE MECHANISM FOR A PHARMACEUTICAL ADMINISTRATION DEVICE |
CN105102019B (en) * | 2013-04-10 | 2019-08-16 | 赛诺菲 | The driving mechanism of medicine delivery device |
TW201511786A (en) | 2013-04-10 | 2015-04-01 | Sanofi Sa | Injection device |
MX2015014293A (en) | 2013-04-10 | 2015-12-08 | Sanofi Sa | Injection device. |
DK2983759T3 (en) | 2013-04-10 | 2018-02-12 | Sanofi Sa | INJECTION DEVICE |
CN105102044A (en) * | 2013-04-10 | 2015-11-25 | 赛诺菲 | Drive mechanism of a drug delivery device |
MX2015014296A (en) | 2013-04-10 | 2015-12-08 | Sanofi Sa | Injection device. |
BR112015023941A2 (en) | 2013-04-10 | 2017-07-18 | Sanofi Sa | injection device |
AR095800A1 (en) | 2013-04-10 | 2015-11-11 | Sanofi Sa | ASSEMBLY METHOD AND INJECTION DEVICE |
US10213560B2 (en) | 2013-04-10 | 2019-02-26 | Sanofi | Injection device |
BR112015024154A2 (en) | 2013-04-10 | 2017-07-18 | Sanofi Sa | dispensing speed control mechanism and injection device |
AR095813A1 (en) | 2013-04-10 | 2015-11-11 | Sanofi Sa | INJECTION DEVICE |
EP2983761B1 (en) | 2013-04-10 | 2017-11-15 | Sanofi | Drive assembly for a drug delivery device |
JP6722102B2 (en) * | 2013-04-10 | 2020-07-15 | サノフイSanofi | Medication rate control mechanism and injection device |
US10092705B2 (en) | 2013-04-10 | 2018-10-09 | Sanofi | Injection device |
US10376651B2 (en) | 2013-04-10 | 2019-08-13 | Sanofi | Injection device |
DK2983739T3 (en) | 2013-04-10 | 2020-06-29 | Sanofi Sa | DRIVE MECHANISM FOR A PHARMACEUTICAL ADMINISTRATION DEVICE |
US9700485B2 (en) | 2013-04-24 | 2017-07-11 | Corning Incorporated | Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients |
KR102296049B1 (en) | 2013-05-16 | 2021-08-30 | 사노피-아벤티스 도이칠란트 게엠베하 | Mechanism for a drug delivery device |
WO2014191190A1 (en) | 2013-05-27 | 2014-12-04 | Sanofi-Aventis Deutschland Gmbh | Drive assembly for a drug delivery device and drug delivery device |
EP2823841A1 (en) | 2013-07-09 | 2015-01-14 | Sanofi-Aventis Deutschland GmbH | Autoinjector |
USRE46814E1 (en) | 2013-07-16 | 2018-05-01 | Sanofi-Aventis Deutschland Gmbh | Medication delivery device |
DK3021913T3 (en) | 2013-07-17 | 2018-01-08 | Sanofi Sa | A drug |
WO2015007825A1 (en) | 2013-07-17 | 2015-01-22 | Sanofi | Drug delivery device |
DK3021909T3 (en) | 2013-07-17 | 2019-04-29 | Sanofi Sa | PHARMACEUTICAL MANAGEMENT DEVICE |
WO2015007820A1 (en) | 2013-07-17 | 2015-01-22 | Sanofi | Drug delivery device |
WO2015007823A1 (en) | 2013-07-17 | 2015-01-22 | Sanofi | Drug delivery device |
JP6426172B2 (en) | 2013-07-17 | 2018-11-21 | サノフイSanofi | Drug delivery device |
BR122021026856B1 (en) | 2013-08-02 | 2023-02-14 | Becton, Dickinson And Company | INJECTION PEN |
AU2014314290B2 (en) | 2013-08-29 | 2018-11-08 | Sanofi-Aventis Deutschland Gmbh | Housing and cap for an injection device made of an outer metal part and an inner plastic part |
HUE047773T2 (en) | 2013-08-29 | 2020-05-28 | Sanofi Aventis Deutschland | Cap for a drug delivery device |
US10220153B2 (en) | 2013-09-03 | 2019-03-05 | Sanofi | Pen type drug injection device with dose limiting nut to prevent setting of a dose higher than the amount of drug remaining |
EP3041538B1 (en) | 2013-09-03 | 2020-06-03 | Sanofi | Drive mechanism and injection device herewith |
JP6457529B2 (en) | 2013-09-03 | 2019-01-23 | サノフイSanofi | Drive mechanism and injection device having drive mechanism |
US10549046B2 (en) * | 2013-09-03 | 2020-02-04 | Sanofi | Drive mechanism for a drug delivery device |
EP2851821A1 (en) | 2013-09-20 | 2015-03-25 | Sanofi-Aventis Deutschland GmbH | Medical device and method operating same |
US9901684B2 (en) | 2013-10-17 | 2018-02-27 | Warsaw Orthopedic, Inc. | Drug delivery device with retaining member |
JP6525993B2 (en) * | 2013-11-15 | 2019-06-05 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | Use of members and assemblies for drug delivery devices, drug delivery devices, and members |
US10328209B2 (en) | 2013-11-15 | 2019-06-25 | Sanofi-Aventis Deutschland Gmbh | Assembly for a drug delivery device and drug delivery device |
WO2015071212A1 (en) | 2013-11-15 | 2015-05-21 | Sanofi-Aventis Deutschland Gmbh | Assembly for a drug delivery device and drug delivery device |
US10525204B2 (en) | 2013-11-22 | 2020-01-07 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device |
EP3071270B1 (en) * | 2013-11-22 | 2024-01-17 | Sanofi-Aventis Deutschland GmbH | Drug delivery device with dose knob clutch |
JP6815198B2 (en) * | 2013-11-22 | 2021-01-20 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | Drug delivery device with unidirectional coupling |
EP3077024B1 (en) | 2013-12-05 | 2018-01-31 | Novo Nordisk A/S | A housing for a medical injection device |
AR098642A1 (en) | 2013-12-09 | 2016-06-01 | Sanofi Aventis Deutschland | DRIVE AND MECHANISM ELEMENT FOR A DRUG SUPPLY DEVICE AND DRUG SUPPLY DEVICE |
TWI709569B (en) | 2014-01-17 | 2020-11-11 | 美商健臻公司 | Sterile chromatography resin and use thereof in manufacturing processes |
EP2923714A1 (en) | 2014-03-28 | 2015-09-30 | Sanofi-Aventis Deutschland GmbH | Autoinjector triggered by skin contact |
DK3125973T3 (en) | 2014-03-31 | 2018-06-18 | Sanofi Aventis Deutschland | PEN-TYPE DEVICE FOR INJECTION OF MEDICINAL PRODUCTS WITH SPECIFIC DOSAGE SCALE AND DOSAGE DISPLAY WINDOW INCLUDING AN OPTICAL FILTER FOR MEANING VIEW OF SET DOSAGE VALUE |
JP6703492B2 (en) | 2014-05-28 | 2020-06-03 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | Dose marking mechanism and drug delivery device for drug delivery device |
CN105214203B (en) * | 2014-06-13 | 2018-09-18 | 中国人民解放军第二军医大学 | A kind of portable intrabone infusion device |
USD770038S1 (en) | 2014-06-26 | 2016-10-25 | Eli Lilly And Company | Medication injection device |
CN105288790B (en) * | 2014-06-26 | 2018-07-03 | 群康生技股份有限公司 | Syringe |
TW201603851A (en) | 2014-07-01 | 2016-02-01 | 賽諾菲公司 | Drug delivery device |
TW201603852A (en) | 2014-07-01 | 2016-02-01 | 賽諾菲公司 | Spring arrangement and drug delivery device herewith |
USD809652S1 (en) | 2014-07-25 | 2018-02-06 | Warsaw Orthopedic, Inc. | Drug delivery device |
US9775978B2 (en) | 2014-07-25 | 2017-10-03 | Warsaw Orthopedic, Inc. | Drug delivery device and methods having a retaining member |
US10080877B2 (en) | 2014-07-25 | 2018-09-25 | Warsaw Orthopedic, Inc. | Drug delivery device and methods having a drug cartridge |
US20170173268A1 (en) * | 2014-07-25 | 2017-06-22 | Novo Nordisk A/S | Nut assembly for a medical device |
AR102189A1 (en) | 2014-10-09 | 2017-02-08 | Sanofi Sa | ACCOMMODATION AND DRUG ADMINISTRATION DEVICE WITH THE SAME AND METHOD TO PRODUCE AN ACCOMMODATION |
AR102191A1 (en) * | 2014-10-09 | 2017-02-08 | Sanofi Sa | METHOD FOR ASSEMBLING A DRIVING SPRING AND DRUG ADMINISTRATION DEVICE WITH A SPRING |
EP3006068B1 (en) * | 2014-10-09 | 2020-12-09 | Ypsomed AG | Medication dispensing apparatus with sub dose prevention |
WO2016091843A1 (en) | 2014-12-08 | 2016-06-16 | Sanofi | Clicker arrangement and drug delivery device herewith |
US10576212B2 (en) | 2014-12-08 | 2020-03-03 | Sanofi | Dose setting mechanism and drug delivery device herewith |
JP6734862B2 (en) | 2014-12-08 | 2020-08-05 | サノフイSanofi | Drive mechanism and drug delivery device having the same |
US11007324B2 (en) | 2014-12-08 | 2021-05-18 | Sanofi | Drug delivery device comprising a prism |
WO2016091869A1 (en) | 2014-12-08 | 2016-06-16 | Sanofi | Drive mechanism for use in a drug delivery device |
CN106999667B (en) | 2014-12-12 | 2019-12-03 | 艾斯曲尔医疗公司 | Dosing mechanism and medicament delivery device including the dosing mechanism |
CA2970200A1 (en) | 2014-12-12 | 2016-06-16 | Sanofi-Aventis Deutschland Gmbh | Insulin glargine/lixisenatide fixed ratio formulation |
US9474864B2 (en) | 2014-12-15 | 2016-10-25 | Brell Medical Innovations, LLC | Safety syringe and methods for administration of a medicament dose by subject weight |
EP3045193A1 (en) * | 2015-01-19 | 2016-07-20 | Sanofi-Aventis Deutschland GmbH | Assembly for a drug delivery device |
EP3058974A1 (en) | 2015-02-19 | 2016-08-24 | Sanofi-Aventis Deutschland GmbH | Injection device with supplementary device |
EP3132821B1 (en) | 2015-03-03 | 2018-12-19 | Innovative Precision Instruments Limited | Drug information detection apparatus and drug information detection type injection apparatus |
EP3265151B1 (en) | 2015-03-06 | 2021-11-24 | Sanofi-Aventis Deutschland GmbH | Sensor arrangement for an injection device |
TWI748945B (en) | 2015-03-13 | 2021-12-11 | 德商賽諾菲阿凡提斯德意志有限公司 | Treatment type 2 diabetes mellitus patients |
TW201705975A (en) | 2015-03-18 | 2017-02-16 | 賽諾菲阿凡提斯德意志有限公司 | Treatment of type 2 diabetes mellitus patients |
JP6758316B2 (en) | 2015-03-23 | 2020-09-23 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | Cartridge holder for injection device |
TWI711472B (en) * | 2015-03-23 | 2020-12-01 | 德商賽諾菲阿凡提斯德意志有限公司 | Housing for an injection device and interconnection of housing components |
WO2016150900A2 (en) | 2015-03-23 | 2016-09-29 | Sanofi-Aventis Deutschland Gmbh | Injection device |
CA2980004C (en) | 2015-03-24 | 2023-10-10 | Kaleo, Inc. | Devices and methods for delivering a lyophilized medicament |
JP6471029B2 (en) * | 2015-04-10 | 2019-02-13 | 株式会社ダイセル | Syringe |
EP3085404A1 (en) | 2015-04-21 | 2016-10-26 | Sanofi-Aventis Deutschland GmbH | Dosing mechanism and drug delivery device |
EP3285837B1 (en) | 2015-04-23 | 2019-06-05 | Sanofi-Aventis Deutschland GmbH | Drug delivery device and retaining member for a drug delivery device |
US10933201B2 (en) | 2015-04-23 | 2021-03-02 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device and predetermined breaking member for a drug delivery device |
ES2797687T3 (en) * | 2015-05-21 | 2020-12-03 | Lilly Co Eli | Injection device control with two gear patterns |
WO2016188983A1 (en) | 2015-05-27 | 2016-12-01 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device |
EP3302628A1 (en) | 2015-05-27 | 2018-04-11 | Sanofi-Aventis Deutschland GmbH | Drug delivery device |
WO2016189089A1 (en) * | 2015-05-28 | 2016-12-01 | Novo Nordisk A/S | Drug delivery device with multifunctional bias structure |
US10799644B2 (en) | 2015-06-01 | 2020-10-13 | Novo Nordisk A/S | Method for moulding a polymeric housing for a medical injection device |
US10426196B2 (en) * | 2015-06-09 | 2019-10-01 | Gofire, Inc. | Portable vaporizer for dosing concentrate material |
PL3307357T5 (en) | 2015-06-09 | 2023-09-18 | Sanofi-Aventis Deutschland Gmbh | Data collection apparatus for attachment to an injection device |
CA2990950A1 (en) | 2015-06-30 | 2017-01-05 | Kaleo, Inc. | Auto-injectors for administration of a medicament within a prefilled syringe |
JP6893509B2 (en) * | 2015-07-21 | 2021-06-23 | バイオコープ プロダクション エス.アー.Biocorp Production S.A. | Dosage control system and related uses for injectable drug delivery devices |
DE202015006841U1 (en) | 2015-09-30 | 2016-01-15 | Haselmeier Ag | injection device |
EP3355905A1 (en) | 2015-09-30 | 2018-08-08 | Rhythm Pharmaceuticals, Inc. | Method of treating melanocortin-4 receptor pathway-associated disorders |
DE202015006842U1 (en) | 2015-09-30 | 2016-01-15 | Haselmeier Ag | injection device |
DE202015006845U1 (en) * | 2015-09-30 | 2016-01-15 | Haselmeier Ag | injection device |
EP3359227B1 (en) | 2015-10-09 | 2020-08-05 | Novo Nordisk A/S | Drug delivery device with slim drive mechanism |
JP6824262B2 (en) * | 2015-10-30 | 2021-02-03 | ノボ・ノルデイスク・エー/エス | Manufacturing method of filled drug delivery device |
US10076650B2 (en) | 2015-11-23 | 2018-09-18 | Warsaw Orthopedic, Inc. | Enhanced stylet for drug depot injector |
PL227678B1 (en) | 2015-12-22 | 2018-01-31 | Copernicus Spolka Z Ograniczona Odpowiedzialnoscia | Control and drive system for the device intended for injection and the device for making injections equipped with such a system |
EA035398B1 (en) * | 2016-03-21 | 2020-06-08 | Эли Лилли Энд Компани | Medical delivery device with axially expandable drive member |
EP3241581A1 (en) | 2016-05-03 | 2017-11-08 | Sanofi-Aventis Deutschland GmbH | Non-releasable snap connection of cartridge holder to syringe |
EP3241580A1 (en) | 2016-05-03 | 2017-11-08 | Sanofi-Aventis Deutschland GmbH | Housing for an injection device |
CN105944186B (en) * | 2016-05-18 | 2019-08-02 | 苏州鹏烨医疗科技有限公司 | A kind of injection pen |
CN106039475B (en) * | 2016-05-18 | 2019-08-02 | 苏州鹏烨医疗科技有限公司 | A kind of injection pen |
US10350348B2 (en) | 2016-05-23 | 2019-07-16 | Lifescan Ip Holdings, Llc | Manually actuated infusion device with display |
JP6940525B2 (en) | 2016-05-30 | 2021-09-29 | ノボ・ノルデイスク・エー/エス | Drug delivery device with zero position adjustment feature |
JP6940526B2 (en) | 2016-05-30 | 2021-09-29 | ノボ・ノルデイスク・エー/エス | Mounting features for accessory devices |
USD820439S1 (en) | 2016-06-13 | 2018-06-12 | Carebay Europe Ltd. | Medicament delivery device |
USD820438S1 (en) | 2016-06-13 | 2018-06-12 | Carebay Europe Ltd. | Medicament delivery device |
USD802755S1 (en) | 2016-06-23 | 2017-11-14 | Warsaw Orthopedic, Inc. | Drug pellet cartridge |
CN105909505B (en) * | 2016-06-29 | 2018-08-17 | 上海康德莱医疗器械股份有限公司 | A kind of dosing electronic pump |
DK3478343T3 (en) | 2016-07-01 | 2021-03-29 | Sanofi Sa | DRUG ADMINISTRATIVE DEVICE |
PL3108914T3 (en) | 2016-07-07 | 2019-08-30 | Copernicus Sp. Z O.O. | Injection device for delivering a defined number of equal doses of a liquid substance |
CN106110443B (en) * | 2016-07-20 | 2022-07-22 | 昆山翰尔西医疗器械有限公司 | Syringe |
US10709845B2 (en) | 2016-07-21 | 2020-07-14 | Amgen Inc. | Drug delivery device with a rotatable drive mechanism |
US9636464B1 (en) | 2016-08-01 | 2017-05-02 | Innovative Precision Instruments Limited | Drug delivery device and a drug information detection device |
CN106389123B (en) * | 2016-10-21 | 2019-01-15 | 浙江瑞邦智能装备股份有限公司 | A kind of novel injector |
JP7046939B2 (en) | 2016-11-01 | 2022-04-04 | サノフィ-アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | Auxiliary device for injection devices |
US10434261B2 (en) | 2016-11-08 | 2019-10-08 | Warsaw Orthopedic, Inc. | Drug pellet delivery system and method |
JP6935497B2 (en) | 2016-12-01 | 2021-09-15 | ノボ・ノルデイスク・エー/エス | Drug delivery device with clutch features |
WO2018104289A1 (en) | 2016-12-07 | 2018-06-14 | Sanofi | Data collection device for attachment to an injection device |
WO2018119218A1 (en) | 2016-12-23 | 2018-06-28 | Kaleo, Inc. | Medicament delivery device and methods for delivering drugs to infants and children |
EP3348298A1 (en) | 2017-01-16 | 2018-07-18 | Novo Nordisk A/S | Drug delivery device with rotationally geared piston rod driver |
CA3165224A1 (en) * | 2017-02-28 | 2018-09-07 | Eli Lilly And Company | Drug identification module for a medication delivery device |
DK3595753T3 (en) | 2017-03-14 | 2024-01-15 | Sanofi Sa | INJECTION DEVICE WITH DEVICE FOR ACOUSTIC FEEDBACK |
JP7389650B2 (en) * | 2017-04-07 | 2023-11-30 | ノボ・ノルデイスク・エー/エス | Content termination mechanism |
JP6670270B2 (en) * | 2017-06-05 | 2020-03-18 | 金井 秀樹 | Chemical liquid injector and chemical liquid discharge amount increase prevention device attached to the chemical liquid injector |
US10688247B2 (en) * | 2017-07-13 | 2020-06-23 | Haselmeier Ag | Injection device with flexible dose selection |
PL232651B1 (en) | 2017-07-18 | 2019-07-31 | Copernicus Spolka Z Ograniczona Odpowiedzialnoscia | Coupling with locking system for the medical injecting device |
CN111050750A (en) | 2017-08-24 | 2020-04-21 | 诺沃挪第克公司 | GLP-1 compositions and uses thereof |
CA3073835A1 (en) | 2017-08-30 | 2019-03-07 | Pirouette Medical LLC | Compact auto-injector |
PL3684447T3 (en) | 2017-09-22 | 2022-10-24 | Novo Nordisk A/S | Accessory device for drug delivery device |
WO2019071129A1 (en) | 2017-10-05 | 2019-04-11 | Pirouette Medical LLC | Protective case for an auto-injector |
WO2019091877A1 (en) | 2017-11-07 | 2019-05-16 | Sanofi-Aventis Deutschland Gmbh | Injection device with a dose limiter |
JP7268020B2 (en) | 2017-11-07 | 2023-05-02 | サノフィ-アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | injection device |
WO2019091881A1 (en) | 2017-11-07 | 2019-05-16 | Sanofi-Aventis Deutschland Gmbh | Injection device with a preselector |
US20210077741A1 (en) | 2017-11-07 | 2021-03-18 | Sanofi-Aventis Deutschland Gmbh | Injection Device with a Preselector |
CN111295214A (en) | 2017-11-07 | 2020-06-16 | 赛诺菲-安万特德国有限公司 | Injection device with pre-selector |
WO2019110494A1 (en) | 2017-12-04 | 2019-06-13 | Novo Nordisk A/S | Drug delivery system with multipolar magnet and sensor system |
EP3495008A1 (en) | 2017-12-06 | 2019-06-12 | Sanofi | Wind-up servo-actuator and drug delivery device |
JP7413262B2 (en) | 2017-12-18 | 2024-01-15 | サノフイ | Rotation sensor for injection devices |
CN111712280B (en) | 2017-12-21 | 2022-09-13 | 赛诺菲 | Transmission of data relating to use of an injection device using passive RF modulation |
WO2019121615A1 (en) | 2017-12-21 | 2019-06-27 | Sanofi | Rfid dose tracking mechanism for injection devices |
JP7286650B2 (en) | 2017-12-21 | 2023-06-05 | サノフイ | RFID dose tracking mechanism for injection devices |
RS64766B1 (en) | 2018-02-22 | 2023-11-30 | Lilly Co Eli | Dose detection system module for medication delivery device |
JP2021524299A (en) | 2018-05-17 | 2021-09-13 | サノフイSanofi | Touch-sensitive label for injection devices |
WO2019219824A1 (en) * | 2018-05-18 | 2019-11-21 | Novo Nordisk A/S | Sensor assembly with identifier determination |
EP3597233A1 (en) * | 2018-07-18 | 2020-01-22 | Sanofi | Drug delivery devices |
CN111084918A (en) * | 2018-10-24 | 2020-05-01 | 群康生技股份有限公司 | Syringe with injection dosage adjusting function |
EP3883626A1 (en) | 2018-11-23 | 2021-09-29 | Sanofi | Electronic-ink label for a drug delivery device |
WO2020114929A1 (en) | 2018-12-04 | 2020-06-11 | Sanofi | Assembly for a drug delivery device, drug delivery device, and method for producing a drug delivery device |
BR112021011680A2 (en) | 2018-12-18 | 2021-09-08 | Sanofi | INJECTION DEVICE |
JP2022550650A (en) | 2019-04-18 | 2022-12-05 | サノフイ | Apparatus for detecting the dose of drug delivered from an injection device |
JP2022531775A (en) | 2019-05-03 | 2022-07-11 | サノフイ | Rotation sensitive placement for injection devices |
CN113950346A (en) | 2019-06-13 | 2022-01-18 | 赛诺菲 | Device for detecting a dose of medicament delivered from an injection device |
WO2020260221A1 (en) | 2019-06-26 | 2020-12-30 | Sanofi | Injection device with a filling level indicator |
WO2021030210A1 (en) | 2019-08-09 | 2021-02-18 | Kaleo, Inc. | Devices and methods for delivery of substances within a prefilled syringe |
CN114641327A (en) | 2019-10-28 | 2022-06-17 | 赛诺菲 | Label for an injection device |
WO2021083834A1 (en) | 2019-10-28 | 2021-05-06 | Sanofi | Electronic label for a drug delivery device |
CN114761056A (en) * | 2019-11-26 | 2022-07-15 | 赛诺菲(中国)投资有限公司 | Dose recording device |
RU197124U1 (en) * | 2019-12-20 | 2020-04-02 | Общество с ограниченной ответственностью "Научно-производственный Инновационный внедренческий центр" | Disposable Inhaler Cartridge |
US20220409819A1 (en) | 2019-12-27 | 2022-12-29 | Sanofi | Apparatus for Detecting a Manipulation of an Injection Device |
EP4106727A1 (en) | 2020-02-18 | 2022-12-28 | Novo Nordisk A/S | Pharmaceutical formulations |
CN115461102A (en) | 2020-04-23 | 2022-12-09 | 赛诺菲 | Drug delivery device |
EP4138964A1 (en) | 2020-04-23 | 2023-03-01 | Sanofi | Injection device with an electronic detector |
CN115551576A (en) | 2020-05-18 | 2022-12-30 | 诺和诺德股份有限公司 | Drug delivery device with squeal during delivery |
EP4157550A1 (en) | 2020-05-29 | 2023-04-05 | Sanofi | Applicator device and applicator system for medicament containers |
CN115697442A (en) | 2020-06-19 | 2023-02-03 | 赛诺菲 | Wearable electronic device |
USD958834S1 (en) * | 2020-07-30 | 2022-07-26 | Sanofi | Display panel portion with an animated computer icon |
USD949195S1 (en) * | 2020-07-30 | 2022-04-19 | Sanofi | Display panel portion with an animated computer icon |
USD953368S1 (en) * | 2020-07-30 | 2022-05-31 | Sanofi | Display panel portion with an animated computer icon |
USD953367S1 (en) * | 2020-07-30 | 2022-05-31 | Sanofi | Display panel portion with an animated computer icon |
USD947889S1 (en) * | 2020-07-30 | 2022-04-05 | Sanofi | Display panel portion with an animated computer icon |
USD953366S1 (en) * | 2020-07-30 | 2022-05-31 | Sanofi | Display panel portion with an animated computer icon |
USD952675S1 (en) * | 2020-07-30 | 2022-05-24 | Sanofi | Display panel portion with an animated computer icon |
USD952674S1 (en) * | 2020-07-30 | 2022-05-24 | Sanofi | Display panel portion with an animated computer icon |
USD958183S1 (en) * | 2020-07-30 | 2022-07-19 | Sanofi | Display panel portion with an animated computer icon |
WO2022144454A1 (en) | 2021-01-04 | 2022-07-07 | Sanofi | Housing component of an injection device comprising a magnifier |
US20240100259A1 (en) | 2021-02-09 | 2024-03-28 | Sanofi | A Dose Counting System |
JP2024505592A (en) | 2021-02-09 | 2024-02-06 | サノフイ | dose counting system |
EP4070832A1 (en) | 2021-04-07 | 2022-10-12 | medmix Switzerland AG | Keyed connectors |
WO2022223748A1 (en) | 2021-04-23 | 2022-10-27 | Sanofi | Electronic encoder module and drug delivery device herewith |
CN117202952A (en) | 2021-05-03 | 2023-12-08 | 赛诺菲 | Housing part for an injection device |
EP4333938A1 (en) | 2021-05-03 | 2024-03-13 | Sanofi | Coded housing components for an injection device |
CN117177787A (en) | 2021-05-03 | 2023-12-05 | 赛诺菲 | Coded housing member for an injection device |
WO2022233751A1 (en) | 2021-05-03 | 2022-11-10 | Sanofi | Coded housing components for an injection device |
EP4333942A1 (en) | 2021-05-03 | 2024-03-13 | Sanofi | Housing components and medicament container for an injection device |
CN117177788A (en) | 2021-05-03 | 2023-12-05 | 赛诺菲 | Housing part for an injection device |
CN117222442A (en) | 2021-05-03 | 2023-12-12 | 赛诺菲 | Coded housing member for an injection device |
WO2023046791A1 (en) | 2021-09-24 | 2023-03-30 | Sanofi | Driving an optical sensor of a drug delivery device or of a drug delivery add-on device |
WO2023046788A1 (en) | 2021-09-24 | 2023-03-30 | Sanofi | Dosing operation speed detection with electronic system for a drug delivery device |
WO2023046795A1 (en) | 2021-09-24 | 2023-03-30 | Sanofi | Tuning of at least one threshold of a sensor of a drug delivery device or of a drug delivery add-on device |
WO2023046796A1 (en) | 2021-09-24 | 2023-03-30 | Sanofi | Controlling a sensor of a drug delivery device or of a drug delivery add-on device |
WO2023046799A1 (en) | 2021-09-24 | 2023-03-30 | Sanofi | Operating an electronic unit of a drug delivery device or a drug delivery add-on device |
WO2023046786A1 (en) | 2021-09-24 | 2023-03-30 | Sanofi | Electronic module, drug delivery device and method for operating an electronic module |
WO2023046803A1 (en) | 2021-09-24 | 2023-03-30 | Sanofi | Data storage on a drug delivery device or on a drug delivery add-on device |
WO2023046800A1 (en) | 2021-09-24 | 2023-03-30 | Sanofi | Information recording in a drug delivery device |
WO2023046794A1 (en) | 2021-09-24 | 2023-03-30 | Sanofi | Determining data related to the approach of end of life of a drug delivery device |
WO2023046793A1 (en) | 2021-09-24 | 2023-03-30 | Sanofi | User interface member for a drug delivery device and drug delivery device |
WO2023046801A1 (en) | 2021-09-24 | 2023-03-30 | Sanofi | Electronic system, user interface member, drug delivery device and method for detecting whether a drug delivery device is, or was, exposed to fluid |
WO2023046798A1 (en) | 2021-09-24 | 2023-03-30 | Sanofi | Electronic component for a drug delivery device |
WO2023046797A1 (en) | 2021-09-24 | 2023-03-30 | Sanofi | Electronic module, drug delivery device and method for operating an electronic module |
WO2023046790A1 (en) | 2021-09-24 | 2023-03-30 | Sanofi | Electronics device with battery life optimisation provided for a drug delivery device or a drug delivery add-on device |
WO2023046802A1 (en) | 2021-09-24 | 2023-03-30 | Sanofi | Checking a sensor of a drug delivery device or of a drug delivery add-on device |
WO2023046805A1 (en) | 2021-09-24 | 2023-03-30 | Sanofi | Component for a drug delivery device and drug delivery device |
WO2023078853A1 (en) | 2021-11-03 | 2023-05-11 | Sanofi | Injection device and method of unlocking operation of the injection device |
WO2023078958A1 (en) | 2021-11-03 | 2023-05-11 | Sanofi | User authentication for a drug delivery device |
WO2023078849A1 (en) | 2021-11-03 | 2023-05-11 | Sanofi | Injection device and method of unlocking operation of the injection device |
WO2023078857A1 (en) | 2021-11-03 | 2023-05-11 | Sanofi | Injection device and method of unlocking operation of the injection device |
WO2023078858A1 (en) | 2021-11-03 | 2023-05-11 | Sanofi | Drug delivery device and electronic unit |
WO2023078957A1 (en) | 2021-11-03 | 2023-05-11 | Sanofi | User authentication for a drug delivery device |
WO2023078861A1 (en) | 2021-11-03 | 2023-05-11 | Sanofi | Supplementary device with integrated locking mechanism |
WO2023078847A1 (en) | 2021-11-03 | 2023-05-11 | Sanofi | Drug delivery device and electronic unit |
WO2023078846A1 (en) | 2021-11-03 | 2023-05-11 | Sanofi | Electronic unit and mobile electronic device for a drug delivery device |
WO2023099513A1 (en) | 2021-12-01 | 2023-06-08 | Sanofi | Drug delivery device and dose recording system herewith |
WO2023099512A1 (en) | 2021-12-01 | 2023-06-08 | Sanofi | Drug delivery device and dose recording system herewith |
WO2023099514A1 (en) | 2021-12-01 | 2023-06-08 | Sanofi | Drug delivery device and dose recording system herewith |
WO2023099515A1 (en) | 2021-12-01 | 2023-06-08 | Sanofi | Drug delivery device and dose recording system herewith |
WO2023131691A1 (en) | 2022-01-10 | 2023-07-13 | Sanofi | Carry case for a drug delivery device and drug delivery device |
WO2023152215A1 (en) | 2022-02-11 | 2023-08-17 | Sanofi | Electrical system for a drug delivery device and drug delivery device |
WO2023213755A1 (en) | 2022-05-03 | 2023-11-09 | Sanofi | Sensor assembly for detecting or recognizing operation an injection device |
WO2023213756A1 (en) | 2022-05-03 | 2023-11-09 | Sanofi | Sensor assembly for an injection device |
WO2023238017A1 (en) * | 2022-06-08 | 2023-12-14 | Zydus Lifesciences Limited | Reusable multi-dose, variable dose, single pen injector for type 2 diabetes and weight management |
WO2023237584A1 (en) | 2022-06-09 | 2023-12-14 | Sanofi | Spacer for an add-on device |
WO2024046935A1 (en) | 2022-08-30 | 2024-03-07 | Sanofi | Add-on device for an injection device |
WO2024046934A1 (en) | 2022-08-30 | 2024-03-07 | Sanofi | Injection device with add-on device |
WO2024046932A1 (en) | 2022-08-30 | 2024-03-07 | Sanofi | Add-on device for an injection device |
WO2024046931A1 (en) | 2022-08-30 | 2024-03-07 | Sanofi | Injection device and add-on device |
WO2024046933A1 (en) | 2022-08-30 | 2024-03-07 | Sanofi | Injection device and add-on device |
WO2024074519A1 (en) | 2022-10-04 | 2024-04-11 | Sanofi | Injection device and method of preparing an injection device for injection |
Family Cites Families (258)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US533575A (en) | 1895-02-05 | wilkens | ||
US186463A (en) | 1877-01-23 | Improvement in flooring | ||
US2444570A (en) | 1948-07-06 | Drive for counter numeral wheels | ||
GB304822A (en) | 1927-10-26 | 1929-01-28 | Gramophone Co Ltd | Improvements in and relating to sound reproducing means |
US2454583A (en) | 1945-06-21 | 1948-11-23 | Wisely Robert | Grating structure |
US2722931A (en) | 1951-01-17 | 1955-11-08 | Becton Dickinson Co | Injection device |
GB735433A (en) | 1952-04-21 | 1955-08-24 | Atomic Energy Authority Uk | Improvements in or relating to columns for liquid-liquid extraction and like processes and packings for such columns |
GB735443A (en) | 1952-09-02 | 1955-08-24 | English Numbering Machines | Improvements in or relating to counting devices |
US2717597A (en) | 1952-12-04 | 1955-09-13 | Jr George N Hein | Injection apparatus |
GB883769A (en) | 1959-09-24 | 1961-12-06 | British Drug Houses Ltd | 3ª-:16ª-:17ª--trihydroxy steroids |
CH499734A (en) | 1968-07-19 | 1970-11-30 | Kienzle Apparate Gmbh | Ratchet lock as one-way and overrunning clutch |
US3815785A (en) | 1972-12-04 | 1974-06-11 | Gilmont R Instr Inc | Micrometric dispenser with calibration means |
US4048960A (en) | 1976-05-05 | 1977-09-20 | Danforth Agri-Resources | Slotted surface flooring for use in animal husbandry |
AU510597B2 (en) | 1976-06-11 | 1980-07-03 | Yelverton Williams Patrick | Split nut |
US4231325A (en) | 1979-06-06 | 1980-11-04 | Parks Donald Merle | Modular, waste collecting and draining floor apparatus |
FR2467149A1 (en) | 1979-10-12 | 1981-04-17 | Lorscheidt Willy | DISPENSER-DOSER FOR PASTY AND LIQUID PRODUCTS |
IE52621B1 (en) * | 1981-02-12 | 1988-01-06 | Turner Robert Charles | Dose metering plunger devices for use with syringes |
US4568335A (en) | 1981-08-28 | 1986-02-04 | Markwell Medical Institute, Inc. | Device for the controlled infusion of medications |
DE3204178C2 (en) | 1982-02-06 | 1986-03-20 | Eppendorf Gerätebau Netheler + Hinz GmbH, 2000 Hamburg | Pipetting device |
GB2141799B (en) | 1983-06-03 | 1986-07-16 | Diehl Gmbh & Co | An adjusting ratchet mechanism for a time switch |
DE3468173D1 (en) | 1983-09-07 | 1988-02-04 | Disetronic Ag | Portable infusion apparatus |
US4592754A (en) | 1983-09-09 | 1986-06-03 | Gupte Pradeep M | Surgical prosthetic vessel graft and catheter combination and method |
US4592745A (en) * | 1984-02-29 | 1986-06-03 | Novo Industri A/S | Dispenser |
FR2583291A1 (en) | 1985-06-14 | 1986-12-19 | Hazon Bernard | Device for step-by-step advance of syringe plungers by means of a double coaxial screw with control of the injection rate. Application to repetitive intradermic medicinal injections |
DE3670768D1 (en) | 1985-11-08 | 1990-06-07 | Disetronic Ag | INJECTION DEVICE. |
DE3609555A1 (en) | 1986-03-21 | 1987-09-24 | Josef Porner | Blood-collecting syringe |
US5716990A (en) | 1987-03-09 | 1998-02-10 | Cancer Research Campaign Technology Limited | Drug delivery systems |
DK177187A (en) | 1987-04-07 | 1988-10-08 | Dcp Af 1988 As | DOSING UNIT FOR DOSING A NUMBER OF MEASURED QUANTITIES OF A FLUID, SUCH AS INSULIN, FROM A GLASS AMPULA |
DE3715258C2 (en) | 1987-05-08 | 1996-10-31 | Haselmeier Wilhelm Fa | Injection device |
DE3715340C2 (en) | 1987-05-08 | 1995-10-19 | Haselmeier Wilhelm Fa | Injection device |
GB8713810D0 (en) | 1987-06-12 | 1987-07-15 | Hypoguard Uk Ltd | Measured dose dispensing device |
US4863072A (en) * | 1987-08-18 | 1989-09-05 | Robert Perler | Single hand operable dental composite package |
US4919596A (en) | 1987-12-04 | 1990-04-24 | Pacesetter Infusion, Ltd. | Fluid delivery control and monitoring apparatus for a medication infusion system |
US4833379A (en) | 1988-01-13 | 1989-05-23 | Sherwood Medical Company | Motor control fail-safe circuit |
CH675078A5 (en) | 1988-01-22 | 1990-08-31 | Nosta Ag | |
US4973318A (en) * | 1988-02-10 | 1990-11-27 | D.C.P. Af 1988 A/S | Disposable syringe |
DK166948B1 (en) | 1988-02-10 | 1993-08-09 | Dcp Af 1988 As | DOSING UNIT FOR DOSING A NUMBER OF MEASURED QUANTITIES OF A FLUID, SUCH AS INSULIN, FROM A GLASS STUBLE |
DE3821969C1 (en) | 1988-06-29 | 1990-02-01 | Michael Dr. 8000 Muenchen De Spaeth | |
ES2069558T3 (en) | 1988-09-12 | 1995-05-16 | Graesslin Kg | DEVICE TO REGULATE THE TIME OF A SWITCH CLOCK. |
US5030209A (en) | 1988-11-09 | 1991-07-09 | Medical Safety Products, Inc. | Holder for double ended blood collection retractable needle |
DE68921856T2 (en) | 1988-12-20 | 1995-12-07 | Toshiba Kawasaki Kk | Soft magnetic Fe-based alloy. |
DK68789A (en) | 1989-02-14 | 1990-08-15 | Novo Nordisk As | injector |
US5000650A (en) | 1989-05-12 | 1991-03-19 | J.I. Case Company | Automatic return to travel |
US4994033A (en) | 1989-05-25 | 1991-02-19 | Schneider (Usa) Inc. | Intravascular drug delivery dilatation catheter |
US5226895A (en) | 1989-06-05 | 1993-07-13 | Eli Lilly And Company | Multiple dose injection pen |
DK17890A (en) | 1990-01-22 | 1991-07-23 | Novo Nordisk As | METHOD AND APPARATUS FOR MIXTURE AND INJECTION OF A MEDICINE |
GB9007113D0 (en) * | 1990-03-29 | 1990-05-30 | Sams Bernard | Dispensing device |
US5207752A (en) | 1990-03-30 | 1993-05-04 | Alza Corporation | Iontophoretic drug delivery system with two-stage delivery profile |
US5318540A (en) | 1990-04-02 | 1994-06-07 | Pharmetrix Corporation | Controlled release infusion device |
US5492534A (en) | 1990-04-02 | 1996-02-20 | Pharmetrix Corporation | Controlled release portable pump |
US5226896A (en) | 1990-04-04 | 1993-07-13 | Eli Lilly And Company | Dose indicating injection pen |
US5257987A (en) | 1990-05-21 | 1993-11-02 | Pharmetrix Corporation | Controlled release osmotic infusion system |
US5107190A (en) | 1990-06-22 | 1992-04-21 | Motorola, Inc. | Means and method for optimizing the switching performance of power amplifiers |
WO1992004926A1 (en) | 1990-09-21 | 1992-04-02 | Novo Nordisk A/S | Adaptor top |
US5284480A (en) | 1990-11-09 | 1994-02-08 | Medtronic, Inc. | Inflation/deflation syringe with threaded plunger |
GB9026191D0 (en) | 1990-12-01 | 1991-01-16 | Harris Pharma Ltd | Breath actuated dispensing device |
US5331954A (en) | 1990-12-21 | 1994-07-26 | Novo Nordisk A/S | Device for nasal delivery of liquid medications |
AU641206B2 (en) | 1991-01-22 | 1993-09-16 | Eli Lilly And Company | Multiple dose injection pen |
DE69203472T2 (en) | 1991-02-07 | 1996-01-04 | Terumo Corp | Dosing device for injector. |
IT221762Z2 (en) | 1991-03-25 | 1994-10-20 | Salvatore Sapienza | MATT SYRINGE |
DE4112259A1 (en) | 1991-04-15 | 1992-10-22 | Medico Dev Investment Co | INJECTION DEVICE |
DK68991D0 (en) | 1991-04-17 | 1991-04-17 | Novo Nordisk As | HEADER |
US5645052A (en) | 1991-04-26 | 1997-07-08 | The Boc Group Plc | Anaesthetic vaporizer with expandable/contractable reservoir for pumping liquid anaesthetic |
GB9109832D0 (en) | 1991-05-07 | 1991-06-26 | Ellis Glynn A | Saw blade machining system |
ES2074771T3 (en) | 1991-07-24 | 1995-09-16 | Medico Dev Investment Co | INJECTOR. |
DK175491D0 (en) * | 1991-10-18 | 1991-10-18 | Novo Nordisk As | APPARATUS |
US5328486A (en) * | 1991-11-19 | 1994-07-12 | American Cyanamid Company | Syringe for dispensing multiple dosages |
DK194291D0 (en) | 1991-11-29 | 1991-11-29 | Novo Nordisk As | SPRAY FOR AUTOMATIC INJECTION. |
US5611783A (en) | 1991-11-29 | 1997-03-18 | Novo Nordisk A/S | Pen-shaped syringe |
US5246417A (en) | 1991-12-11 | 1993-09-21 | Alza Corporation | Indicator for iontophoresis system |
US5279585A (en) | 1992-02-04 | 1994-01-18 | Becton, Dickinson And Company | Medication delivery pen having improved dose delivery features |
CH682806A5 (en) | 1992-02-21 | 1993-11-30 | Medimpex Ets | Injection device. |
WO1993018812A1 (en) | 1992-03-25 | 1993-09-30 | Tebro S.A. | Powder jet dispenser for medicament inhalation therapies |
US5271527A (en) | 1992-04-02 | 1993-12-21 | Habley Medical Technology Corporation | Reusable pharmaceutical dispenser with full stroke indicator |
US5281198A (en) | 1992-05-04 | 1994-01-25 | Habley Medical Technology Corporation | Pharmaceutical component-mixing delivery assembly |
US5300041A (en) | 1992-06-01 | 1994-04-05 | Habley Medical Technology Corporation | Dose setting and repeating syringe |
UA26190C2 (en) | 1992-07-28 | 1999-07-19 | Сейфтек Ай Лімітед | Syringe |
GB9219849D0 (en) | 1992-09-19 | 1992-10-28 | Hypoguard Uk Ltd | Device |
EP0649316B2 (en) | 1992-10-15 | 2013-08-28 | The General Hospital Corporation | An infusion pump with an electronically loadable drug library |
US5545147A (en) | 1992-10-20 | 1996-08-13 | Eli Lilly And Company | Anti-backup improvement for hypodermic syringes |
US5391157A (en) | 1992-10-20 | 1995-02-21 | Eli Lilly And Company | End of dose indicator |
US5378233A (en) | 1992-11-18 | 1995-01-03 | Habley Medical Technology Corporation | Selected dose pharmaceutical dispenser |
US5547131A (en) | 1992-12-04 | 1996-08-20 | Bespak Plc | Dispensing device with spray nozzle and driven piston |
US5320609A (en) * | 1992-12-07 | 1994-06-14 | Habley Medical Technology Corporation | Automatic pharmaceutical dispensing syringe |
GB9226423D0 (en) * | 1992-12-18 | 1993-02-10 | Sams Bernard | Incrementing mechanisms |
FR2701211B1 (en) | 1993-02-08 | 1995-05-24 | Aguettant Lab | DOSING INSTRUMENT, ESPECIALLY INJECTION |
US5478324A (en) | 1993-02-19 | 1995-12-26 | Medicorp Holding S.A. | Prefilled syringe for storing and for transfer of liquid and sterile medicinal substances |
US5383865A (en) | 1993-03-15 | 1995-01-24 | Eli Lilly And Company | Medication dispensing device |
US5584815A (en) | 1993-04-02 | 1996-12-17 | Eli Lilly And Company | Multi-cartridge medication injection device |
ZA941881B (en) | 1993-04-02 | 1995-09-18 | Lilly Co Eli | Manifold medication injection apparatus and method |
US5591135A (en) | 1993-04-12 | 1997-01-07 | Sullivan; James J. | Syringe stroke controller with elastically enabled single axis slide adjustment and finger-molded pistol grip |
SE9301494D0 (en) * | 1993-04-30 | 1993-04-30 | Kabi Pharmacia Ab | A DEVICE FOR DOSING LIQUID PREPARATION |
SE9303568D0 (en) | 1993-10-29 | 1993-10-29 | Kabi Pharmacia Ab | Improvements in injection devices |
US5478316A (en) | 1994-02-02 | 1995-12-26 | Becton, Dickinson And Company | Automatic self-injection device |
EP0667469A1 (en) | 1994-02-14 | 1995-08-16 | Akram Fado | Ratchet mechanism exploiting both strokes of the ratchet motion |
US5562623A (en) | 1994-02-14 | 1996-10-08 | Univec | Single-use syringe assembly including spring clip lock and plunger |
US5514097A (en) | 1994-02-14 | 1996-05-07 | Genentech, Inc. | Self administered injection pen apparatus and method |
US5536249A (en) | 1994-03-09 | 1996-07-16 | Visionary Medical Products, Inc. | Pen-type injector with a microprocessor and blood characteristic monitor |
US5634300A (en) | 1994-03-10 | 1997-06-03 | Plascore Inc. | Wall system employing grooved posts, connector blocks and T-bolt receiving battens |
AU1595395A (en) | 1994-06-15 | 1996-01-05 | Interventional Research Technologies, Inc. | Locking device for syringe or like instrument |
US5725508A (en) * | 1994-06-22 | 1998-03-10 | Becton Dickinson And Company | Quick connect medication delivery pen |
US5827232A (en) | 1994-06-22 | 1998-10-27 | Becton Dickinson And Company | Quick connect medication delivery pen |
US5440976A (en) | 1994-08-23 | 1995-08-15 | Fred Giuliano | Adjustable dispensing stirrer for soluble sweeteners |
CA2186869A1 (en) | 1994-08-24 | 1996-02-29 | Hideto Yamagata | Injection apparatus |
US5549574A (en) | 1994-08-30 | 1996-08-27 | Eli Lilly And Company | Cartridge assembly for use in a pen-type medicament injector |
US5549575A (en) | 1994-09-13 | 1996-08-27 | Becton Dickinson And Company | Cartridge retainer assembly for medication delivery pen |
US5582598A (en) | 1994-09-19 | 1996-12-10 | Becton Dickinson And Company | Medication delivery pen with variable increment dose scale |
JP3712130B2 (en) | 1994-09-20 | 2005-11-02 | ノボザイムス アクティーゼルスカブ | Method for treating aqueous protein solution to kill microorganisms therein without causing coagulation |
ZA958073B (en) | 1994-09-28 | 1996-04-23 | Anthony William Manicom | Method of and apparatus for administering a drug to a patient |
US5690618A (en) | 1995-02-22 | 1997-11-25 | Mark Timothy Smith | Electronic syringe |
GB9503969D0 (en) | 1995-02-28 | 1995-04-19 | Sams Bernard | Incrementing mechanism |
AU696439B2 (en) | 1995-03-07 | 1998-09-10 | Eli Lilly And Company | Recyclable medication dispensing device |
US5503628A (en) | 1995-03-15 | 1996-04-02 | Jettek, Inc. | Patient-fillable hypodermic jet injector |
US5562047A (en) | 1995-05-19 | 1996-10-08 | New Pig Corporation | Modular spill deck |
WO1996038190A1 (en) | 1995-06-02 | 1996-12-05 | Novo Nordisk A/S | Automatic withdrawal of piston rod |
US5882598A (en) * | 1995-06-09 | 1999-03-16 | Scp Global Technologies | Wafer gap conductivity cell for characterizing process vessels and semiconductor fabrication processes and method of use |
AU1860697A (en) | 1995-09-08 | 1997-07-28 | Visionary Medical Products Corporation | Pen-type injector drive mechanism |
US5674204A (en) * | 1995-09-19 | 1997-10-07 | Becton Dickinson And Company | Medication delivery pen cap actuated dose delivery clutch |
US5688251A (en) * | 1995-09-19 | 1997-11-18 | Becton Dickinson And Company | Cartridge loading and priming mechanism for a pen injector |
DK0802810T3 (en) | 1995-11-09 | 2001-11-26 | Disetronic Licensing Ag | Injection device for receiving a liquid drug |
US5692640A (en) | 1995-12-05 | 1997-12-02 | Caulfield; Patricia E. | Syringe content identification system |
US5899879A (en) * | 1995-12-19 | 1999-05-04 | Genesis Medical Technologies, Inc. | Spring-actuated needleless injector |
CN1138575C (en) | 1996-02-23 | 2004-02-18 | 诺沃挪第克公司 | Syringe with electronic representation of parameters |
UA35653C2 (en) | 1996-03-12 | 2001-04-16 | Ново Нордіск А/С | Device for injection |
WO1997036625A1 (en) | 1996-04-02 | 1997-10-09 | Disetronic Licensing Ag | Injection device |
EP0828527B1 (en) | 1996-04-02 | 2002-07-31 | Disetronic Licensing AG | Injection device |
AU724937B2 (en) | 1996-04-24 | 2000-10-05 | Novo Nordisk A/S | Injection needle |
CA2258491A1 (en) | 1996-07-05 | 1998-01-15 | Novo Nordisk A/S | Automatic needle insertion mechanism |
WO1998001173A1 (en) | 1996-07-05 | 1998-01-15 | Novo Nordisk A/S | Flexible piston rod |
CA2258308A1 (en) | 1996-07-05 | 1998-01-15 | Novo Nordisk A/S | Dose setting device |
US5709662A (en) | 1996-08-23 | 1998-01-20 | Becton Dickinson France, S.A. | Cartridge for an injection device |
US5843036A (en) | 1996-08-23 | 1998-12-01 | Becton Dickinson And Company | Non-dosing cartridge for an injection device |
US5947934A (en) | 1996-09-13 | 1999-09-07 | Novo Nordisk A/S | Dose display for an injection syringe |
US6379339B1 (en) | 1996-09-13 | 2002-04-30 | Nova Nordisk A/S | Syringe |
DK0927057T3 (en) | 1996-09-13 | 2003-09-01 | Novo Nordisk As | Dose display means for a syringe |
US6110149A (en) | 1996-09-13 | 2000-08-29 | Novo Nordisk A/S | Syringe |
JP2001501504A (en) | 1996-09-20 | 2001-02-06 | ノボ ノルディスク アクティーゼルスカブ | Working cylinder |
US6146361A (en) | 1996-09-26 | 2000-11-14 | Becton Dickinson And Company | Medication delivery pen having a 31 gauge needle |
US5851079A (en) | 1996-10-25 | 1998-12-22 | The Procter & Gamble Company | Simplified undirectional twist-up dispensing device with incremental dosing |
US5954689A (en) | 1996-12-20 | 1999-09-21 | Novo Nordisk A/S | Jet injector |
GB2321419B (en) | 1997-01-27 | 2001-02-07 | Medic Aid Ltd | Atomizer |
JP2001511033A (en) | 1997-02-04 | 2001-08-07 | ノボ ノルディスク アクティーゼルスカブ | Liquid drug suspension dosing device |
DE29703820U1 (en) | 1997-03-03 | 1998-07-02 | Medico Dev Investment Co | Injection device |
US5898028A (en) | 1997-03-20 | 1999-04-27 | Novo Nordisk A/S | Method for producing powder formulation comprising an insulin |
US6277097B1 (en) | 1997-03-25 | 2001-08-21 | Novo Nordisk A/S | Injection system |
RU2111019C1 (en) | 1997-05-22 | 1998-05-20 | Сергей Александрович Хворостов | General-purpose injector |
US6454746B1 (en) | 1997-06-04 | 2002-09-24 | Eli Lilly And Company | Medication delivery apparatus |
US6074372A (en) | 1997-06-09 | 2000-06-13 | Novo Nordisk A/S | Dose setting mechanism and an injection syringe having such a dose setting mechanism |
US6003736A (en) | 1997-06-09 | 1999-12-21 | Novo Nordisk A/S | Device for controlled dispensing of a dose of a liquid contained in a cartridge |
US6796970B1 (en) | 1997-06-17 | 2004-09-28 | Novo Nordisk A/S | Dose setting device |
US5961496A (en) | 1997-06-17 | 1999-10-05 | Novo Nordisk A/S | Syringe with tiltable nut for quick piston disengagement |
AU7331598A (en) | 1997-07-11 | 1999-02-08 | Novo Nordisk A/S | An apparatus for the registration of the setting of a medical device |
AU8333298A (en) | 1997-07-14 | 1999-02-10 | Novo Nordisk A/S | Cylinder ampoule |
AU8333398A (en) | 1997-07-14 | 1999-02-10 | Novo Nordisk A/S | Injection member |
DE19730999C1 (en) | 1997-07-18 | 1998-12-10 | Disetronic Licensing Ag | Injection pen dosing selected volume of fluid, especially insulin |
JPH1134710A (en) | 1997-07-24 | 1999-02-09 | Bridgestone Corp | Seat with seating sensor |
US5921966A (en) | 1997-08-11 | 1999-07-13 | Becton Dickinson And Company | Medication delivery pen having an improved clutch assembly |
FR2767479B1 (en) | 1997-08-22 | 1999-10-22 | Aguettant Lab | DRUG INJECTION DEVICE |
AU9202398A (en) | 1997-09-29 | 1999-04-23 | Becton Dickinson & Company | Injection device and drug cartridge for preventing cross-use of the device and drug cartridge |
US6312413B1 (en) | 1997-10-30 | 2001-11-06 | Novo Nordisk A/S | Cylinder ampoule |
CA2305634C (en) | 1998-01-30 | 2006-01-03 | Novo Nordisk A/S | An injection syringe |
US5961465A (en) | 1998-02-10 | 1999-10-05 | Hewlett-Packard Company | Ultrasound signal processing electronics with active cooling |
DE69931354T2 (en) | 1998-02-13 | 2007-02-01 | Bioniche Life Sciences Inc., Belleville | DEVICE FOR ADMINISTERING A MEDICAMENT |
US5961495A (en) | 1998-02-20 | 1999-10-05 | Becton, Dickinson And Company | Medication delivery pen having a priming mechanism |
US6221053B1 (en) * | 1998-02-20 | 2001-04-24 | Becton, Dickinson And Company | Multi-featured medication delivery pen |
US6248095B1 (en) * | 1998-02-23 | 2001-06-19 | Becton, Dickinson And Company | Low-cost medication delivery pen |
US6281225B1 (en) | 1998-06-11 | 2001-08-28 | Cerus Corporation | Inhibiting proliferation of arterial smooth muscle cells |
PL345336A1 (en) | 1998-07-08 | 2001-12-17 | Novo Nordisk As | A medical delivery device and a cartridge assembly for use in the same |
US6033376A (en) | 1998-09-30 | 2000-03-07 | Allergan Sales, Inc. | Wound shaper sleeve |
US6605067B1 (en) | 1998-11-20 | 2003-08-12 | Novo Nordisk A/S | Injection needle |
DE19900827C1 (en) | 1999-01-12 | 2000-08-17 | Disetronic Licensing Ag | Device for the dosed administration of an injectable product |
DE19900792C1 (en) | 1999-01-12 | 2000-06-15 | Disetronic Licensing Ag | Injection unit forming part of e.g. pen-type self-injection syringe has continuous dosing stop in spiral form with constant pitch ensuring close fine control and accuracy in use |
DE29900482U1 (en) | 1999-01-14 | 2000-08-31 | Medico Dev Investment Co | Injection device |
US6258062B1 (en) | 1999-02-25 | 2001-07-10 | Joseph M. Thielen | Enclosed container power supply for a needleless injector |
SE9901366D0 (en) | 1999-04-16 | 1999-04-16 | Pharmacia & Upjohn Ab | Injector device and method for its operation |
ATE318157T1 (en) | 1999-08-05 | 2006-03-15 | Becton Dickinson Co | PEN-SHAPED MEDICATION DELIVERY DEVICE |
US6277099B1 (en) | 1999-08-06 | 2001-08-21 | Becton, Dickinson And Company | Medication delivery pen |
US20020077582A1 (en) * | 1999-09-03 | 2002-06-20 | Baxter International Inc. | Blood processing systems and methods that assess and respond to real or potential vein occlusion conditions |
TW453884B (en) | 1999-09-16 | 2001-09-11 | Novo Nordisk As | Dose setting limiter |
US6514230B1 (en) | 1999-10-12 | 2003-02-04 | Novo Nordisk A/S | Air shot mechanism for electronic injection devices |
DE10052471B4 (en) * | 1999-11-08 | 2012-08-23 | Schaeffler Technologies Gmbh & Co. Kg | cone pulley |
TW450923B (en) | 2000-01-11 | 2001-08-21 | Procter & Gamble | Reversibly collapsible/erectable container and method of using |
US6379399B1 (en) | 2000-02-16 | 2002-04-30 | Bristol-Myers Squibb Company | Oxidation hair dyeing systems and process for providing more equalized coloration on new and old growth hair |
GB0007071D0 (en) * | 2000-03-24 | 2000-05-17 | Sams Bernard | One-way clutch mechanisms and injector devices |
US6692472B2 (en) | 2000-05-04 | 2004-02-17 | Novo Nordisk A/S | Injection device, a preassembled dose setting and injection mechanism for an injection device, and a method of assembling an injection device |
DE60137034D1 (en) | 2000-05-04 | 2009-01-29 | Novo Nordisk As | METHOD FOR COMPOSING AN INJECTION DEVICE WITH PRE-ASSEMBLED DOSAGE ADJUSTMENT AND INJECTION MECHANISM |
US6716198B2 (en) | 2000-05-18 | 2004-04-06 | Novo Nordisk A/S | Injection device |
US6547763B2 (en) | 2000-05-18 | 2003-04-15 | Novo Nordisk A/S | Dose display for injection device |
US6547764B2 (en) | 2000-05-31 | 2003-04-15 | Novo Nordisk A/S | Double pointed injection needle |
US6663602B2 (en) * | 2000-06-16 | 2003-12-16 | Novo Nordisk A/S | Injection device |
ATE386563T1 (en) | 2000-07-14 | 2008-03-15 | Novo Nordisk As | LIQUID DISPENSING DEVICE AND METHOD FOR REDUCING DRIPPING |
AU2001289589A1 (en) | 2000-09-22 | 2002-04-02 | Novo-Nordisk A/S | A medication delivery device |
IL154683A0 (en) | 2000-10-09 | 2003-09-17 | Lilly Co Eli | Pen device for administration of parathyroid hormone |
JP2002143001A (en) | 2000-11-08 | 2002-05-21 | Orugo Kk | Cap of container |
US6899699B2 (en) | 2001-01-05 | 2005-05-31 | Novo Nordisk A/S | Automatic injection device with reset feature |
WO2002064196A1 (en) | 2001-02-14 | 2002-08-22 | Novo Nordisk A/S | Electronically controlled injection or infusion device |
US20020165499A1 (en) | 2001-04-13 | 2002-11-07 | Slate John B. | Jet injector having a mechanism for creating air-in-tip |
ATE513570T1 (en) | 2001-05-16 | 2011-07-15 | Lilly Co Eli | SPRAY DEVICE WITH DRIVE DEVICE WHICH SIMPLIFIES RESETTING |
GB0113881D0 (en) | 2001-06-07 | 2001-08-01 | Innovate Biomed Ltd | Foil cutting system |
DE10163326A1 (en) | 2001-07-30 | 2003-02-27 | Disetronic Licensing Ag | Administration device with dosing device |
GB0200444D0 (en) | 2002-01-10 | 2002-02-27 | Owen Mumford Ltd | Improvements relating to medical injection devices |
GB2384431A (en) | 2002-01-25 | 2003-07-30 | Medical House Plc | Needleless injector having an audible dose indicator |
AU2003209475A1 (en) | 2002-03-07 | 2003-09-16 | Vectura Limited | Fast melt multiparticulate formulations for oral delivery |
GB0205485D0 (en) | 2002-03-08 | 2002-04-24 | Dca Design Int Ltd | Improvements in and relating to a medicament delivery service |
WO2003080160A1 (en) | 2002-03-18 | 2003-10-02 | Eli Lilly And Company | Medication dispensing apparatus with gear set for mechanical advantage |
JP4228586B2 (en) | 2002-05-21 | 2009-02-25 | 富士電機デバイステクノロジー株式会社 | Semiconductor device |
JP2005532129A (en) | 2002-07-10 | 2005-10-27 | ノボ・ノルデイスク・エー/エス | Syringe with dose setting limiter |
US6945961B2 (en) | 2002-07-10 | 2005-09-20 | Novo Nordisk A/S | Injection device |
DE10232412A1 (en) * | 2002-07-17 | 2004-02-05 | Disetronic Licensing Ag | Administration device with priming function |
EP1391794A1 (en) | 2002-07-23 | 2004-02-25 | Novo Nordisk A/S | Device with time indicating means |
DE10237258B4 (en) | 2002-08-14 | 2006-09-21 | Tecpharma Licensing Ag | injection device |
WO2004020026A1 (en) | 2002-08-29 | 2004-03-11 | Novo Nordisk A/S | Frontloaded injection device |
JP3906988B2 (en) | 2002-08-30 | 2007-04-18 | 日本電産サンキョー株式会社 | motor |
AU2003275353A1 (en) * | 2002-10-01 | 2004-04-23 | Becton, Dickinson And Company | Medication delivery pen |
US20050019400A1 (en) | 2003-01-27 | 2005-01-27 | Deveney Thomas William | Controlled-release drug delivery system |
GB0304822D0 (en) | 2003-03-03 | 2003-04-09 | Dca Internat Ltd | Improvements in and relating to a pen-type injector |
GB0304823D0 (en) | 2003-03-03 | 2003-04-09 | Dca Internat Ltd | Improvements in and relating to a pen-type injector |
US9205197B2 (en) | 2003-03-03 | 2015-12-08 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device dose setting mechanism |
GB0304824D0 (en) | 2003-03-03 | 2003-04-09 | Dca Internat Ltd | Improvements in and relating to a pen-type injector |
US6923145B2 (en) | 2003-03-20 | 2005-08-02 | Michael Wahl | Flume flush floor for livestock |
GB0306642D0 (en) | 2003-03-22 | 2003-04-30 | Dca Design Int Ltd | Improvements in and relating to an injector for a medical product |
US6932794B2 (en) * | 2003-04-03 | 2005-08-23 | Becton, Dickinson And Company | Medication delivery pen |
GB0308267D0 (en) | 2003-04-10 | 2003-05-14 | Dca Design Int Ltd | Improvements in and relating to a pen-type injector |
CN100531813C (en) * | 2003-08-12 | 2009-08-26 | 伊莱利利公司 | Medication dispensing apparatus with triple screw threads for mechanical advantage |
EP1541185A1 (en) | 2003-12-08 | 2005-06-15 | Novo Nordisk A/S | Automatic syringe with priming mechanism |
US7448385B2 (en) | 2004-06-07 | 2008-11-11 | Purepharm Inc. | Nasal adaptation of an oral inhaler device |
US7690160B2 (en) | 2004-07-23 | 2010-04-06 | Moller Jr Jorgen J | Modular floor tile system with transition edge |
EP1642607A1 (en) * | 2004-10-04 | 2006-04-05 | Sanofi-Aventis Deutschland GmbH | Dose display mechanism for a drug delivery device |
JP4922172B2 (en) * | 2004-10-04 | 2012-04-25 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | Drive mechanism for drug delivery device |
EP1645301A1 (en) | 2004-10-11 | 2006-04-12 | Novo Nordisk A/S | Injection device |
DE602005026595D1 (en) | 2004-12-01 | 2011-04-07 | Novo Nordisk As | injection device |
DE102004063645A1 (en) | 2004-12-31 | 2006-07-20 | Tecpharma Licensing Ag | Device for metered administration of a fluid product with decoupling for a container change |
US8257318B2 (en) | 2005-02-11 | 2012-09-04 | Novo Nordisk A/S | Injection device having a rotatable scale drum |
US9101722B2 (en) | 2005-02-28 | 2015-08-11 | Novo Nordisk A/S | Dose setting mechanism for an injection device capable of presetting a maximum dose |
EP1877121B1 (en) | 2005-04-24 | 2015-09-23 | Novo Nordisk A/S | Injection device |
US9011386B2 (en) * | 2005-06-01 | 2015-04-21 | Shl Group Ab | Device for delivering medicament |
JP4994370B2 (en) | 2005-07-08 | 2012-08-08 | ノボ・ノルデイスク・エー/エス | Injection device |
USD533575S1 (en) | 2006-01-03 | 2006-12-12 | Creative Technology Ltd | Camera |
US7490443B1 (en) | 2006-03-01 | 2009-02-17 | Bike Track, Inc. | Modular flooring system |
US20100042054A1 (en) | 2006-11-17 | 2010-02-18 | Novo Nordisk A/S | Medical Delivery System Comprising a Coding Mechanism Between Dosing Assembly and Medicament Container |
ES2488667T3 (en) | 2007-01-22 | 2014-08-28 | Teva Pharmaceutical Industries Ltd | Syringe that has a syringe label |
US8267900B2 (en) | 2008-05-02 | 2012-09-18 | Sanofi-Aventis Deutschland Gmbh | Medication delivery device |
US8647309B2 (en) * | 2008-05-02 | 2014-02-11 | Sanofi-Aventis Deutschland Gmbh | Medication delivery device |
US8205398B2 (en) | 2008-08-19 | 2012-06-26 | Building Materials Investment Corp. | Fascia vent |
CA2647230A1 (en) | 2008-12-17 | 2010-06-17 | David Robert Hundeby | Raised floor heating and cooling system for buildings |
WO2010097116A1 (en) | 2009-02-26 | 2010-09-02 | Tecpharma Licensing Ag | Product container holder for an injection device and for receiving a product container |
US8672896B2 (en) * | 2009-06-01 | 2014-03-18 | Sanofi-Aventis Deutschland Gmbh | Inner housing for a drug delivery device |
US8257319B2 (en) * | 2009-06-01 | 2012-09-04 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device inner housing having helical spline |
KR101027514B1 (en) | 2009-06-15 | 2011-04-06 | 삼성전기주식회사 | Input Device |
EP2451508B1 (en) * | 2009-07-08 | 2013-11-06 | Novo Nordisk A/S | Frost protected injection device |
EP2493532B1 (en) | 2009-10-30 | 2019-07-10 | Sanofi-Aventis Deutschland GmbH | Drug delivery device |
US8517729B2 (en) | 2010-03-04 | 2013-08-27 | The University of Western Ontario and Trudell Medical International | Oral mouthpiece and method for the use thereof |
US8505131B2 (en) | 2010-07-27 | 2013-08-13 | Perimedrain Systems, LLC | Trench drain system and method of installation on level floor surface, paticulary for shower rooms |
TWI464003B (en) * | 2010-11-18 | 2014-12-11 | Shl Group Ab | Medicament delivery device |
HUE025080T2 (en) * | 2011-03-25 | 2016-01-28 | Sanofi Aventis Deutschland | Dose setting mechanism and injection device |
ES2941078T3 (en) * | 2012-08-31 | 2023-05-16 | Sanofi Aventis Deutschland | drug delivery device |
RU2015122657A (en) | 2012-11-13 | 2017-01-10 | СЭЙФСПИЛЛ СИСТЕМЗ ЭлЭлСи | MODULAR FIRE-PROOF FLOOR |
DK2983735T3 (en) * | 2013-04-10 | 2021-03-01 | Sanofi Sa | DRIVE MECHANISM FOR A MEDICINE ADMINISTRATIVE DEVICE |
-
2003
- 2003-03-03 GB GBGB0304822.0A patent/GB0304822D0/en not_active Ceased
-
2004
- 2004-03-02 US US10/790,225 patent/US20040267208A1/en not_active Abandoned
- 2004-03-03 PL PL08012347T patent/PL1974761T3/en unknown
- 2004-03-03 DK DK10184400.9T patent/DK2266648T3/en active
- 2004-03-03 DK DK10184248.2T patent/DK2263723T3/en active
- 2004-03-03 ES ES10184248T patent/ES2413432T3/en not_active Expired - Lifetime
- 2004-03-03 DE DE602004019351T patent/DE602004019351D1/en not_active Expired - Lifetime
- 2004-03-03 SI SI200431650T patent/SI1974761T1/en unknown
- 2004-03-03 DK DK10184516.2T patent/DK2263724T3/en active
- 2004-03-03 PT PT101841633T patent/PT2263722E/en unknown
- 2004-03-03 SI SI200430952T patent/SI1603610T1/en unknown
- 2004-03-03 EP EP10184516.2A patent/EP2263724B1/en not_active Expired - Lifetime
- 2004-03-03 PL PL10184163T patent/PL2263722T3/en unknown
- 2004-03-03 SI SI200432043T patent/SI2281592T1/en unknown
- 2004-03-03 PL PL10184516T patent/PL2263724T3/en unknown
- 2004-03-03 TW TW093105523A patent/TWI340654B/en active
- 2004-03-03 PL PL10184248T patent/PL2263723T3/en unknown
- 2004-03-03 EP EP04716568A patent/EP1603610B1/en not_active Expired - Lifetime
- 2004-03-03 DE DE202004021469U patent/DE202004021469U1/en not_active Expired - Lifetime
- 2004-03-03 DE DE202004021470U patent/DE202004021470U1/en not_active Expired - Lifetime
- 2004-03-03 US US10/790,866 patent/US20050033244A1/en not_active Abandoned
- 2004-03-03 ES ES10184347T patent/ES2415854T3/en not_active Expired - Lifetime
- 2004-03-03 AR ARP040100665A patent/AR043459A1/en active IP Right Grant
- 2004-03-03 WO PCT/EP2004/002115 patent/WO2004078239A1/en active IP Right Grant
- 2004-03-03 CA CA2518013A patent/CA2518013C/en not_active Expired - Fee Related
- 2004-03-03 AT AT08012347T patent/ATE497398T1/en active
- 2004-03-03 SI SI200432041T patent/SI2263721T1/en unknown
- 2004-03-03 PL PL10184085T patent/PL2263721T3/en unknown
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