CA2480019A1 - Bioprosthesis and method for suturelessly making same - Google Patents

Bioprosthesis and method for suturelessly making same Download PDF

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Publication number
CA2480019A1
CA2480019A1 CA002480019A CA2480019A CA2480019A1 CA 2480019 A1 CA2480019 A1 CA 2480019A1 CA 002480019 A CA002480019 A CA 002480019A CA 2480019 A CA2480019 A CA 2480019A CA 2480019 A1 CA2480019 A1 CA 2480019A1
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CA
Canada
Prior art keywords
valve
bonding
energy
biomaterial
irradiating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002480019A
Other languages
French (fr)
Other versions
CA2480019C (en
Inventor
Hua Xie
Lisa A. Buckley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Providence Health System Oregon
Original Assignee
Providence Health System-Oregon
Hua Xie
Lisa A. Buckley
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Providence Health System-Oregon, Hua Xie, Lisa A. Buckley filed Critical Providence Health System-Oregon
Publication of CA2480019A1 publication Critical patent/CA2480019A1/en
Application granted granted Critical
Publication of CA2480019C publication Critical patent/CA2480019C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
    • A61F2/2418—Scaffolds therefor, e.g. support stents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2475—Venous valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2220/0025—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
    • A61F2220/0075—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements sutured, ligatured or stitched, retained or tied with a rope, string, thread, wire or cable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
    • A61F2230/0017—Angular shapes
    • A61F2230/0026—Angular shapes trapezoidal

Abstract

A bioprosthetic valve graft (1) comprises a valve frame (10) and valve flaps (12), the latter acting to open or close a valve aperture (14) to directionally control fluid flow through the bioprosthesis (1). The bioprosthetic valve graft (1) comprises a biomaterial suturelessly bonded to the valve frame (10), avoiding sutures and substantially reducing medical complications in implantations.

Claims (45)

1. A valve graft adapted to be implanted in a patient, comprising:
a valve frame defining a valve frame open area; and a sheet of biomaterial suturelessly attached to said valve frame and spanning said valve frame open area.
2. The valve graft of claim 1, wherein said sheet is small intestine submucosa.
3. The valve graft of claim 2, wherein said sheet is substantially comprised of collagen.
4. The valve graft of claim 1, wherein said sheet is constructed to a selected thickness.
5. The valve graft of claim 1, wherein said sheet has an aperture across a short axis of the valve frame open area.
6. The valve graft of claim 1, wherein said valve frame consists of shape memory material.
7. The valve graft of claim 1, wherein said valve is adapted to be vascularly implanted.
8. The valve graft of claim 1, wherein said valve is adapted to be intraluminally implanted.
9. The valve graft of claim 1, wherein said valve is adapted to be implanted in a heart.
10. A method for producing a sutureless valve graft suitable for physiological implantation, comprising:
positioning a flexible valve frame defining an open area on a first major surface of a biomaterial sheet having a peripheral edge, said positioning serving to approximate the valve frame and the peripheral edge of the biomaterial sheet to form an at least first bonding locus; and suturelessly bonding the biomaterial to the valve frame at the at least first bonding locus.
11. The method of claim 10, wherein positioning comprises:
positioning the valve frame on the first major surface of the biomaterial sheet; and folding the edge of the biomaterial sheet over the valve frame so that the edge of the biomaterial sheet is contacted with the first major surface of the biomaterial sheet.
12. The method of claim 10, wherein suturelessly bonding comprises suturelessly bonding the edge of the biomaterial sheet directly to the valve frame.
13. The method of claim 10, further comprising:
applying a distorting force to the valve frame to distort the valve frame into a flexed state prior to positioning the valve frame; and releasing the distorting force after suturelessly bonding.
14. The method of claim 10, wherein the biomaterial sheet consists essentially of small intestine submucosa.
15. The method of claim 10, wherein suturelessly bonding comprises irradiating the at least first bonding locus with energy sufficient to at least partially fuse the portion of the approximated biomaterial sheet to attach the biomaterial to the valve frame at the at least first bonding locus.
16. The method of claim 15, wherein irradiating the at least first bonding locus with energy comprises irradiating the at least first bonding locus with light.
17. The method of claim 16, wherein irradiating the at least first bonding locus with energy comprises irradiating the at least first bonding locus with light generated by a laser.
18. The method of claim 17, wherein irradiating the at least first bonding locus with energy comprises irradiating the at least first bonding locus with light having a wavelength of about 800 nm.
19. The method of claim 18, further comprising introducing a chromophore that is energy-absorptive at about 800 nm.
20. The method of claim 10, further comprising introducing a photo-chemical crosslinking agent.
21. The method of claim 20, wherein said photo-chemical crosslinking agent is methylene blue.
22. The method of claim 21, wherein irradiating the at least first bonding locus with energy comprises irradiating the at least first bonding locus with white light.
23. The method of claim 21, wherein irradiating the at least first bonding locus with energy comprises irradiating the at least first bonding locus with ultraviolet light.
24. The method of claim 15, wherein irradiating the at least first bonding locus with energy comprises irradiating the at least first bonding locus with radio-frequency energy.
25. The method of claim 15, wherein irradiating the at least first bonding locus with energy comprises irradiating the at least first bonding locus with ultrasound energy.
26. The method of claim 10, further comprising creating an aperture across a short axis of the biomaterial sheet.
27. The method of claim 10, further comprising dehydrating the biomaterial prior to suturelessly bonding; and rehydrating the biomaterial after suturelessly bonding.
28. The method of claim 10, further comprising securing the valve frame in the flexed state by attaching a diametric suture, wherein releasing the distorting force comprises removing the diametric suture.
29. A method for suturelessly attaching a collagen-rich biomaterial sheet to a prosthesis frame element, comprising:
approximating a portion of the biomaterial sheet to the prosthesis frame element to define an at least first bonding locus;
irradiating the at least first bonding locus with energy from an energy-generating source, said energy sufficient to at least partially fuse the portion of the approximated biomaterial sheet.
30. The method of claim 29, wherein irradiating the at least first bonding locus with energy from an energy-generating source comprises irradiating the at least first bonding locus with energy from a radio-frequency device.
31. The method of claim 29, wherein irradiating the at least first bonding locus with energy from an energy-generating source comprises irradiating the at least first bonding locus with energy from an ultrasound device.
32. The method of claim 29, wherein irradiating the at least first bonding locus with energy from an energy-generating source comprises irradiating the at least first bonding locus with light energy from a laser.
33. The method of claim 32, wherein said laser emits light having a wavelength of about 800 nm.
34. The method of claim 32, further comprising introducing a chromophore.~
35. The method of claim 34, wherein said chromophore is indocyanine green.
36. The method of claim 29, wherein irradiating the at least first bonding locus with energy from an energy-generating source comprises contacting the at least first bonding locus with a contact thermo-electric transducer.
37. The method of claim 29, further comprising dehydrating the biomaterial prior to bonding; and rehydrating the biomaterial after bonding.
38. The method of claim 29, wherein the prosthesis frame element comprises a synthetic material.
39. The method of claim 29, wherein the prosthesis frame element comprises a biomaterial.
40. The method of claim 29, wherein the biomaterial consists essentially of collagen.
41. The method of claim 29, wherein the biomaterial substantially comprises small intestine submucosa.
42. A method for implanting a sutureless valve graft in a patient, comprising:
providing a sutureless valve graft including a valve frame defining a valve frame open area and a biomaterial sheet being suturelessly attached to said valve frame and spanning said valve frame open area;
flexing the valve graft into a folded state;
introducing the folded valve graft to an implantation site in the patient;
unflexing the valve graft to at least partially unfold same at the implantation site.
43. The method of claim 42, wherein flexing the valve graft comprises folding the valve frame to compress the valve graft into an elongate shape having an aspect ratio greater than 1:1.
44. The method of claim 42, wherein said flexing is performed substantially perpendicular to an aperture in the biomaterial sheet.
45. The method of claim 42, wherein introducing the folded valve graft is via a catheter.
CA2480019A 2002-03-21 2003-03-21 Bioprosthesis and method for suturelessly making same Expired - Fee Related CA2480019C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/104,499 US7163556B2 (en) 2002-03-21 2002-03-21 Bioprosthesis and method for suturelessly making same
US10/104,499 2002-03-21
PCT/US2003/008903 WO2003079928A2 (en) 2002-03-21 2003-03-21 Bioprosthesis and method for suturelessly making same

Publications (2)

Publication Number Publication Date
CA2480019A1 true CA2480019A1 (en) 2003-10-02
CA2480019C CA2480019C (en) 2010-05-11

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CA2480019A Expired - Fee Related CA2480019C (en) 2002-03-21 2003-03-21 Bioprosthesis and method for suturelessly making same

Country Status (6)

Country Link
US (2) US7163556B2 (en)
EP (1) EP1494616A4 (en)
AU (1) AU2003218344A1 (en)
CA (1) CA2480019C (en)
MX (1) MXPA04009159A (en)
WO (1) WO2003079928A2 (en)

Families Citing this family (156)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7452371B2 (en) * 1999-06-02 2008-11-18 Cook Incorporated Implantable vascular device
US6254564B1 (en) 1998-09-10 2001-07-03 Percardia, Inc. Left ventricular conduit with blood vessel graft
US6440164B1 (en) * 1999-10-21 2002-08-27 Scimed Life Systems, Inc. Implantable prosthetic valve
AU2001238038B2 (en) * 2000-02-03 2005-08-25 Cook Biotech, Inc. Implantable vascular device
DE10010073B4 (en) * 2000-02-28 2005-12-22 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Anchoring for implantable heart valve prostheses
DE10010074B4 (en) 2000-02-28 2005-04-14 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Device for fastening and anchoring heart valve prostheses
AU2001270375A1 (en) * 2000-06-16 2001-12-24 Mcgill University Kefir extract as an anti-cancer agent
CA2419811A1 (en) 2000-08-18 2002-02-28 Atritech, Inc. Expandable implant devices for filtering blood flow from atrial appendages
WO2004030568A2 (en) * 2002-10-01 2004-04-15 Ample Medical, Inc. Device and method for repairing a native heart valve leaflet
US6602286B1 (en) 2000-10-26 2003-08-05 Ernst Peter Strecker Implantable valve system
FR2828263B1 (en) 2001-08-03 2007-05-11 Philipp Bonhoeffer DEVICE FOR IMPLANTATION OF AN IMPLANT AND METHOD FOR IMPLANTATION OF THE DEVICE
US7007698B2 (en) * 2002-04-03 2006-03-07 Boston Scientific Corporation Body lumen closure
US6752828B2 (en) * 2002-04-03 2004-06-22 Scimed Life Systems, Inc. Artificial valve
AU2003285943B2 (en) * 2002-10-24 2008-08-21 Boston Scientific Limited Venous valve apparatus and method
US6945957B2 (en) * 2002-12-30 2005-09-20 Scimed Life Systems, Inc. Valve treatment catheter and methods
JP2006515791A (en) * 2003-01-24 2006-06-08 アプライド メディカル リソーシーズ コーポレイション Internal tissue retractor
EP1603492B1 (en) * 2003-03-12 2009-12-23 Cook Incorporated Prosthetic valve that permits retrograde flow
US7175656B2 (en) * 2003-04-18 2007-02-13 Alexander Khairkhahan Percutaneous transcatheter heart valve replacement
US7320083B2 (en) * 2003-04-23 2008-01-15 Dot Hill Systems Corporation Apparatus and method for storage controller to deterministically kill one of redundant servers integrated within the storage controller chassis
EP1626681B1 (en) 2003-05-19 2009-07-01 Cook Incorporated Implantable medical device with constrained expansion
EP1653888B1 (en) * 2003-07-21 2009-09-09 The Trustees of The University of Pennsylvania Percutaneous heart valve
US7854761B2 (en) * 2003-12-19 2010-12-21 Boston Scientific Scimed, Inc. Methods for venous valve replacement with a catheter
US8128681B2 (en) 2003-12-19 2012-03-06 Boston Scientific Scimed, Inc. Venous valve apparatus, system, and method
US8182528B2 (en) 2003-12-23 2012-05-22 Sadra Medical, Inc. Locking heart valve anchor
US11278398B2 (en) 2003-12-23 2022-03-22 Boston Scientific Scimed, Inc. Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements
US7329279B2 (en) 2003-12-23 2008-02-12 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US8343213B2 (en) * 2003-12-23 2013-01-01 Sadra Medical, Inc. Leaflet engagement elements and methods for use thereof
US7445631B2 (en) 2003-12-23 2008-11-04 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US7780725B2 (en) 2004-06-16 2010-08-24 Sadra Medical, Inc. Everting heart valve
US7381219B2 (en) 2003-12-23 2008-06-03 Sadra Medical, Inc. Low profile heart valve and delivery system
US8603160B2 (en) 2003-12-23 2013-12-10 Sadra Medical, Inc. Method of using a retrievable heart valve anchor with a sheath
US7959666B2 (en) 2003-12-23 2011-06-14 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a heart valve
US7988724B2 (en) 2003-12-23 2011-08-02 Sadra Medical, Inc. Systems and methods for delivering a medical implant
US8052749B2 (en) 2003-12-23 2011-11-08 Sadra Medical, Inc. Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements
EP2526898B1 (en) 2003-12-23 2013-04-17 Sadra Medical, Inc. Repositionable heart valve
US8840663B2 (en) 2003-12-23 2014-09-23 Sadra Medical, Inc. Repositionable heart valve method
US20050137687A1 (en) 2003-12-23 2005-06-23 Sadra Medical Heart valve anchor and method
US9526609B2 (en) * 2003-12-23 2016-12-27 Boston Scientific Scimed, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US20120041550A1 (en) 2003-12-23 2012-02-16 Sadra Medical, Inc. Methods and Apparatus for Endovascular Heart Valve Replacement Comprising Tissue Grasping Elements
US8579962B2 (en) 2003-12-23 2013-11-12 Sadra Medical, Inc. Methods and apparatus for performing valvuloplasty
US9005273B2 (en) * 2003-12-23 2015-04-14 Sadra Medical, Inc. Assessing the location and performance of replacement heart valves
US20050137694A1 (en) 2003-12-23 2005-06-23 Haug Ulrich R. Methods and apparatus for endovascularly replacing a patient's heart valve
US7862610B2 (en) * 2004-01-23 2011-01-04 James Quintessenza Bicuspid vascular valve and methods for making and implanting same
US7320705B2 (en) * 2004-01-23 2008-01-22 James Quintessenza Bicuspid pulmonary heart valve and method for making same
EP1737390A1 (en) * 2004-04-08 2007-01-03 Cook Incorporated Implantable medical device with optimized shape
US7276078B2 (en) * 2004-06-30 2007-10-02 Edwards Lifesciences Pvt Paravalvular leak detection, sealing, and prevention
US7566343B2 (en) 2004-09-02 2009-07-28 Boston Scientific Scimed, Inc. Cardiac valve, system, and method
JP4589395B2 (en) * 2004-09-10 2010-12-01 クック インコーポレイテッド Prosthetic valve with holes
US7544207B2 (en) * 2004-10-06 2009-06-09 Cook Incorporated Medical device with bioactive agent
US7563276B2 (en) * 2004-10-29 2009-07-21 Cook Incorporated Intraluminal medical device with cannula for controlled retrograde flow
US20060161248A1 (en) * 2004-12-01 2006-07-20 Case Brian C Medical device with leak path
DE102005003632A1 (en) 2005-01-20 2006-08-17 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Catheter for the transvascular implantation of heart valve prostheses
US20060173490A1 (en) 2005-02-01 2006-08-03 Boston Scientific Scimed, Inc. Filter system and method
US7854755B2 (en) * 2005-02-01 2010-12-21 Boston Scientific Scimed, Inc. Vascular catheter, system, and method
US7878966B2 (en) 2005-02-04 2011-02-01 Boston Scientific Scimed, Inc. Ventricular assist and support device
US7670368B2 (en) * 2005-02-07 2010-03-02 Boston Scientific Scimed, Inc. Venous valve apparatus, system, and method
US7780722B2 (en) 2005-02-07 2010-08-24 Boston Scientific Scimed, Inc. Venous valve apparatus, system, and method
US7867274B2 (en) * 2005-02-23 2011-01-11 Boston Scientific Scimed, Inc. Valve apparatus, system and method
US8303647B2 (en) * 2005-03-03 2012-11-06 Cook Medical Technologies Llc Medical valve leaflet structures with peripheral region receptive to tissue ingrowth
US20060276882A1 (en) 2005-04-11 2006-12-07 Cook Incorporated Medical device including remodelable material attached to frame
US7722666B2 (en) * 2005-04-15 2010-05-25 Boston Scientific Scimed, Inc. Valve apparatus, system and method
US7962208B2 (en) 2005-04-25 2011-06-14 Cardiac Pacemakers, Inc. Method and apparatus for pacing during revascularization
US8012198B2 (en) 2005-06-10 2011-09-06 Boston Scientific Scimed, Inc. Venous valve, system, and method
EP1928512B1 (en) * 2005-09-01 2012-11-14 Cook Medical Technologies LLC Attachment of material to an implantable frame by cross-linking
US7569071B2 (en) 2005-09-21 2009-08-04 Boston Scientific Scimed, Inc. Venous valve, system, and method with sinus pocket
DE102005051849B4 (en) 2005-10-28 2010-01-21 JenaValve Technology Inc., Wilmington Device for implantation and attachment of heart valve prostheses
DE102005052628B4 (en) * 2005-11-04 2014-06-05 Jenavalve Technology Inc. Self-expanding, flexible wire mesh with integrated valvular prosthesis for the transvascular heart valve replacement and a system with such a device and a delivery catheter
US20070213813A1 (en) * 2005-12-22 2007-09-13 Symetis Sa Stent-valves for valve replacement and associated methods and systems for surgery
US7799038B2 (en) * 2006-01-20 2010-09-21 Boston Scientific Scimed, Inc. Translumenal apparatus, system, and method
US20070265584A1 (en) * 2006-02-15 2007-11-15 Hickman Robert O Venous prosthesis and vascular graft with access port
US7867283B2 (en) * 2006-05-30 2011-01-11 Boston Scientific Scimed, Inc. Anti-obesity diverter structure
WO2008091493A1 (en) 2007-01-08 2008-07-31 California Institute Of Technology In-situ formation of a valve
US8105375B2 (en) * 2007-01-19 2012-01-31 The Cleveland Clinic Foundation Method for implanting a cardiovascular valve
US7967853B2 (en) * 2007-02-05 2011-06-28 Boston Scientific Scimed, Inc. Percutaneous valve, system and method
WO2008097556A1 (en) * 2007-02-05 2008-08-14 Boston Scientific Limited Systems and methods for valve delivery
US9138315B2 (en) * 2007-04-13 2015-09-22 Jenavalve Technology Gmbh Medical device for treating a heart valve insufficiency or stenosis
US7896915B2 (en) * 2007-04-13 2011-03-01 Jenavalve Technology, Inc. Medical device for treating a heart valve insufficiency
AU2008250552B2 (en) * 2007-05-15 2012-03-08 Jenavalve Technology Inc. Handle for manipulating a catheter tip, catheter system and medical insertion system for inserting a self-expandable heart valve stent
US8828079B2 (en) * 2007-07-26 2014-09-09 Boston Scientific Scimed, Inc. Circulatory valve, system and method
US7892276B2 (en) * 2007-12-21 2011-02-22 Boston Scientific Scimed, Inc. Valve with delayed leaflet deployment
US20090171456A1 (en) * 2007-12-28 2009-07-02 Kveen Graig L Percutaneous heart valve, system, and method
US9044318B2 (en) 2008-02-26 2015-06-02 Jenavalve Technology Gmbh Stent for the positioning and anchoring of a valvular prosthesis
US8465540B2 (en) 2008-02-26 2013-06-18 Jenavalve Technology, Inc. Stent for the positioning and anchoring of a valvular prosthesis
US8317858B2 (en) 2008-02-26 2012-11-27 Jenavalve Technology, Inc. Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
ES2903231T3 (en) 2008-02-26 2022-03-31 Jenavalve Tech Inc Stent for positioning and anchoring a valve prosthesis at an implantation site in a patient's heart
US8398704B2 (en) 2008-02-26 2013-03-19 Jenavalve Technology, Inc. Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
US9168130B2 (en) * 2008-02-26 2015-10-27 Jenavalve Technology Gmbh Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient
EP2340075B1 (en) 2008-10-10 2013-03-06 Sadra Medical, Inc. Medical devices and delivery systems for delivering medical devices
GB2470083A (en) * 2009-05-08 2010-11-10 Nat Univ Ireland Closed loop stent
US20100292779A1 (en) * 2009-05-15 2010-11-18 Helmut Straubinger Device for compressing a stent and a system as well as a method for loading a stent into a medical delivery system
FR2951549B1 (en) 2009-10-15 2013-08-23 Olivier Schussler PROCESS FOR OBTAINING IMPLANTABLE MEDICAL BIOPROTHESES
US10856978B2 (en) 2010-05-20 2020-12-08 Jenavalve Technology, Inc. Catheter system
US11278406B2 (en) 2010-05-20 2022-03-22 Jenavalve Technology, Inc. Catheter system for introducing an expandable heart valve stent into the body of a patient, insertion system with a catheter system and medical device for treatment of a heart valve defect
CN103002833B (en) 2010-05-25 2016-05-11 耶拿阀门科技公司 Artificial heart valve and comprise artificial heart valve and support through conduit carry interior prosthese
CN103108611B (en) 2010-09-10 2016-08-31 西美蒂斯股份公司 Valve replacement device
EP2520251A1 (en) 2011-05-05 2012-11-07 Symetis SA Method and Apparatus for Compressing Stent-Valves
EP2731550B1 (en) 2011-07-12 2016-02-24 Boston Scientific Scimed, Inc. Coupling system for a replacement valve
US9668859B2 (en) 2011-08-05 2017-06-06 California Institute Of Technology Percutaneous heart valve delivery systems
CA2852369A1 (en) 2011-10-21 2013-04-25 Jenavalve Technology Inc. Catheter system for introducing an expandable heart valve stent into the body of a patient, insertion system with a catheter system and medical device for treatment of a heart valve defect
US8951243B2 (en) 2011-12-03 2015-02-10 Boston Scientific Scimed, Inc. Medical device handle
WO2013112547A1 (en) 2012-01-25 2013-08-01 Boston Scientific Scimed, Inc. Valve assembly with a bioabsorbable gasket and a replaceable valve implant
EP3281608B1 (en) 2012-02-10 2020-09-16 CVDevices, LLC Medical product comprising a frame and visceral pleura
EP2849678B1 (en) 2012-05-16 2022-08-10 JenaValve Technology, Inc. Catheter delivery system for introducing an expandable heart valve prosthesis and medical device for the treatment of a heart valve defect
US9883941B2 (en) 2012-06-19 2018-02-06 Boston Scientific Scimed, Inc. Replacement heart valve
US9283072B2 (en) 2012-07-25 2016-03-15 W. L. Gore & Associates, Inc. Everting transcatheter valve and methods
US10966820B2 (en) 2012-12-19 2021-04-06 W. L. Gore & Associates, Inc. Geometric control of bending character in prosthetic heart valve leaflets
US10039638B2 (en) 2012-12-19 2018-08-07 W. L. Gore & Associates, Inc. Geometric prosthetic heart valves
US9101469B2 (en) 2012-12-19 2015-08-11 W. L. Gore & Associates, Inc. Prosthetic heart valve with leaflet shelving
US9737398B2 (en) 2012-12-19 2017-08-22 W. L. Gore & Associates, Inc. Prosthetic valves, frames and leaflets and methods thereof
US9968443B2 (en) 2012-12-19 2018-05-15 W. L. Gore & Associates, Inc. Vertical coaptation zone in a planar portion of prosthetic heart valve leaflet
US9144492B2 (en) 2012-12-19 2015-09-29 W. L. Gore & Associates, Inc. Truncated leaflet for prosthetic heart valves, preformed valve
CA2900862C (en) 2013-02-11 2017-10-03 Cook Medical Technologies Llc Expandable support frame and medical device
US9744037B2 (en) 2013-03-15 2017-08-29 California Institute Of Technology Handle mechanism and functionality for repositioning and retrieval of transcatheter heart valves
US9867694B2 (en) 2013-08-30 2018-01-16 Jenavalve Technology Inc. Radially collapsible frame for a prosthetic valve and method for manufacturing such a frame
US10314697B2 (en) 2014-08-18 2019-06-11 W. L. Gore & Associates, Inc. Frame with integral sewing cuff for prosthetic valves
US9827094B2 (en) 2014-09-15 2017-11-28 W. L. Gore & Associates, Inc. Prosthetic heart valve with retention elements
US9901445B2 (en) 2014-11-21 2018-02-27 Boston Scientific Scimed, Inc. Valve locking mechanism
WO2016115375A1 (en) 2015-01-16 2016-07-21 Boston Scientific Scimed, Inc. Displacement based lock and release mechanism
US9861477B2 (en) 2015-01-26 2018-01-09 Boston Scientific Scimed Inc. Prosthetic heart valve square leaflet-leaflet stitch
US9788942B2 (en) 2015-02-03 2017-10-17 Boston Scientific Scimed Inc. Prosthetic heart valve having tubular seal
US10201417B2 (en) 2015-02-03 2019-02-12 Boston Scientific Scimed Inc. Prosthetic heart valve having tubular seal
US10285809B2 (en) 2015-03-06 2019-05-14 Boston Scientific Scimed Inc. TAVI anchoring assist device
US10426617B2 (en) 2015-03-06 2019-10-01 Boston Scientific Scimed, Inc. Low profile valve locking mechanism and commissure assembly
US10080652B2 (en) 2015-03-13 2018-09-25 Boston Scientific Scimed, Inc. Prosthetic heart valve having an improved tubular seal
CN107530168B (en) 2015-05-01 2020-06-09 耶拿阀门科技股份有限公司 Device and method with reduced pacemaker ratio in heart valve replacement
WO2017004377A1 (en) 2015-07-02 2017-01-05 Boston Scientific Scimed, Inc. Adjustable nosecone
US10195392B2 (en) 2015-07-02 2019-02-05 Boston Scientific Scimed, Inc. Clip-on catheter
US10179041B2 (en) 2015-08-12 2019-01-15 Boston Scientific Scimed Icn. Pinless release mechanism
US10136991B2 (en) 2015-08-12 2018-11-27 Boston Scientific Scimed Inc. Replacement heart valve implant
US10143554B2 (en) * 2015-12-03 2018-12-04 Medtronic Vascular, Inc. Venous valve prostheses
US10342660B2 (en) 2016-02-02 2019-07-09 Boston Scientific Inc. Tensioned sheathing aids
US10583005B2 (en) 2016-05-13 2020-03-10 Boston Scientific Scimed, Inc. Medical device handle
WO2017195125A1 (en) 2016-05-13 2017-11-16 Jenavalve Technology, Inc. Heart valve prosthesis delivery system and method for delivery of heart valve prosthesis with introducer sheath and loading system
US10201416B2 (en) 2016-05-16 2019-02-12 Boston Scientific Scimed, Inc. Replacement heart valve implant with invertible leaflets
CN110392557A (en) 2017-01-27 2019-10-29 耶拿阀门科技股份有限公司 Heart valve simulation
EP3634311A1 (en) 2017-06-08 2020-04-15 Boston Scientific Scimed, Inc. Heart valve implant commissure support structure
US10898325B2 (en) 2017-08-01 2021-01-26 Boston Scientific Scimed, Inc. Medical implant locking mechanism
WO2019035966A1 (en) 2017-08-16 2019-02-21 Boston Scientific Scimed, Inc. Replacement heart valve commissure assembly
CN111182856B (en) 2017-09-12 2022-04-29 W.L.戈尔及同仁股份有限公司 Leaflet frame attachment for prosthetic valves
CN115024861A (en) 2017-09-27 2022-09-09 W.L.戈尔及同仁股份有限公司 Prosthetic valve with mechanically coupled leaflets
CA3178271A1 (en) 2017-09-27 2019-04-04 W.L. Gore & Associates, Inc. Prosthetic valve with expandable frame and associated systems and methods
CA3078699C (en) 2017-10-13 2023-10-10 W.L. Gore & Associates, Inc. Telescoping prosthetic valve and delivery system
US11154397B2 (en) 2017-10-31 2021-10-26 W. L. Gore & Associates, Inc. Jacket for surgical heart valve
JP7227240B2 (en) 2017-10-31 2023-02-21 ダブリュ．エル．ゴア アンド アソシエイツ，インコーポレイティド artificial heart valve
WO2019089135A1 (en) 2017-10-31 2019-05-09 W. L. Gore & Associates, Inc. Transcatheter deployment systems and associated methods
AU2018362079B2 (en) 2017-10-31 2021-09-16 Edwards Lifesciences Corporation Medical valve and leaflet promoting tissue ingrowth
JP7047106B2 (en) 2018-01-19 2022-04-04 ボストン サイエンティフィック サイムド，インコーポレイテッド Medical device delivery system with feedback loop
EP3740160A2 (en) 2018-01-19 2020-11-25 Boston Scientific Scimed Inc. Inductance mode deployment sensors for transcatheter valve system
WO2019157156A1 (en) 2018-02-07 2019-08-15 Boston Scientific Scimed, Inc. Medical device delivery system with alignment feature
WO2019165394A1 (en) 2018-02-26 2019-08-29 Boston Scientific Scimed, Inc. Embedded radiopaque marker in adaptive seal
WO2019222367A1 (en) 2018-05-15 2019-11-21 Boston Scientific Scimed, Inc. Replacement heart valve commissure assembly
US11241310B2 (en) 2018-06-13 2022-02-08 Boston Scientific Scimed, Inc. Replacement heart valve delivery device
USD926322S1 (en) 2018-11-07 2021-07-27 W. L. Gore & Associates, Inc. Heart valve cover
US11241312B2 (en) 2018-12-10 2022-02-08 Boston Scientific Scimed, Inc. Medical device delivery system including a resistance member
US11497601B2 (en) 2019-03-01 2022-11-15 W. L. Gore & Associates, Inc. Telescoping prosthetic valve with retention element
US11439504B2 (en) 2019-05-10 2022-09-13 Boston Scientific Scimed, Inc. Replacement heart valve with improved cusp washout and reduced loading

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2749447B2 (en) 1991-03-25 1998-05-13 ミードックス メディカルズ インコーポレイテッド Artificial blood vessel
US5370685A (en) * 1991-07-16 1994-12-06 Stanford Surgical Technologies, Inc. Endovascular aortic valve replacement
US5258023A (en) * 1992-02-12 1993-11-02 Reger Medical Development, Inc. Prosthetic heart valve
US5571216A (en) 1994-01-19 1996-11-05 The General Hospital Corporation Methods and apparatus for joining collagen-containing materials
US5693085A (en) 1994-04-29 1997-12-02 Scimed Life Systems, Inc. Stent with collagen
US6087552A (en) 1994-11-15 2000-07-11 Sisters Of Providence Of Oregon Method of producing fused biomaterials and tissue
DK0925077T3 (en) 1996-08-23 2003-12-08 Cook Biotech Inc Process for obtaining a purified collagen-based matrix from submucosal tissue
AU743779B2 (en) 1996-12-10 2002-02-07 Cook Biotech, Inc. Tubular grafts from purified submucosa
JP2001505807A (en) * 1996-12-10 2001-05-08 パーデュー・リサーチ・ファウンデーション Artificial vascular valve
US6494904B1 (en) * 1996-12-27 2002-12-17 Ramus Medical Technologies Method and apparatus for forming vascular prostheses
US6077296A (en) * 1998-03-04 2000-06-20 Endologix, Inc. Endoluminal vascular prosthesis
US7452371B2 (en) * 1999-06-02 2008-11-18 Cook Incorporated Implantable vascular device
US6936067B2 (en) * 2001-05-17 2005-08-30 St. Jude Medical Inc. Prosthetic heart valve with slit stent

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US7322932B2 (en) 2008-01-29
US20030181974A1 (en) 2003-09-25

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