CA2452040A1 - Porous sponge matrix medical devices and methods - Google Patents

Porous sponge matrix medical devices and methods Download PDF

Info

Publication number
CA2452040A1
CA2452040A1 CA002452040A CA2452040A CA2452040A1 CA 2452040 A1 CA2452040 A1 CA 2452040A1 CA 002452040 A CA002452040 A CA 002452040A CA 2452040 A CA2452040 A CA 2452040A CA 2452040 A1 CA2452040 A1 CA 2452040A1
Authority
CA
Canada
Prior art keywords
sponge matrix
matrix
medical device
sponge
dry
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002452040A
Other languages
French (fr)
Other versions
CA2452040C (en
Inventor
F. Joseph Obermiller
Michael C. Hiles
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cook Biotech Inc
Original Assignee
Cook Biotech Incorporated
F. Joseph Obermiller
Michael C. Hiles
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cook Biotech Incorporated, F. Joseph Obermiller, Michael C. Hiles filed Critical Cook Biotech Incorporated
Publication of CA2452040A1 publication Critical patent/CA2452040A1/en
Application granted granted Critical
Publication of CA2452040C publication Critical patent/CA2452040C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/146—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/12181—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device formed by fluidized, gelatinous or cellular remodelable materials, e.g. embolic liquids, foams or extracellular matrices
    • A61B17/1219—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device formed by fluidized, gelatinous or cellular remodelable materials, e.g. embolic liquids, foams or extracellular matrices expandable in contact with liquids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0028—Polypeptides; Proteins; Degradation products thereof
    • A61L26/0033—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/0085—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/043—Proteins; Polypeptides; Degradation products thereof
    • A61L31/044—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02—Instruments for taking cell samples or for biopsy
    • A61B10/0233—Pointed or sharp biopsy instruments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00004—(bio)absorbable, (bio)resorbable, resorptive
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A61B2017/00637—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect for sealing trocar wounds through abdominal wall
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A61B2017/00646—Type of implements
    • A61B2017/00654—Type of implements entirely comprised between the two sides of the opening
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00831—Material properties
    • A61B2017/00898—Material properties expandable upon contact with fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/04—Materials for stopping bleeding

Abstract

Described are hemostasis devices useful for implantation in biopsy tracts, which devices comprise highly compact, dried hemostatic sponge elements.
Preferred devices also include compacted sponge matrices exhibiting high density and rigidity in combination with high volumetric expandability when wetted. Also described are methods for making and using such devices.

Claims (45)

1. A medical device, comprising:
a dry sponge matrix defining pores, said sponge matrix stabilized in a compressed configuration and expansible when wetted.
2. The medical device of claim 1, wherein said sponge matrix is formed from matrix-forming material including collagen.
3. The medical device of claim 1, wherein said device is configured for percutaneous delivery.
4. The medical device of claim 2, wherein said device is configured for percutaneous delivery.
5. The medical device of claim 1, wherein said dry sponge matrix is expansible at least about 100% by volume when saturated with deionized water.
6. The medical device of claim 2, wherein said dry sponge matrix is expansible at least about 100% by volume when saturated with deionized water.
7. The medical device of claim 6, wherein said dry sponge matrix has a density of least about 0.05g/cm3.
8. The medical device of claim 7, wherein said dry sponge matrix has a density in the range of about 0.05g/cm3 to about 0.2g/cm3.
9. The medical device of claim 8, wherein said dry sponge matrix has a density in the range of about 0.075g/cm3 to about 0.2g/cm3.
10. The medical device of claim 1, wherein said sponge matrix comprises at least one biotropic agent.
11. The medical device of claim 1, wherein said sponge matrix comprises collagen from an extracellular matrix.
12. The medical device of claim 12, wherein said sponge matrix comprises at least one active biotropic agent from said extracellular matrix.
13. The medical device of claim 12, wherein said extracellular matrix is submucosa or basement membrane.
14. The medical device of claim 12, wherein said extracellular matrix is submucosa or basement membrane.
15. The medical device of claim 2, wherein said sponge matrix is crosslinked.
16. The medical device of claim 15, wherein said sponge matrix is crosslinked with a chemical crosslinking agent providing polar groups in the matrix.
17. The medical device of claim 16, wherein said crosslinking agent is a polyepoxide compound.
18. The medical device of claim 17, wherein said polyexpoxide compound is a polyglycidyl ether compound.
19. The medical device of claim 18, wherein said polygylcidyl ether compound is a diglycidyl ether compound.
20. A method for preparing a compressed sponge matrix, comprising, comprising:
providing a wetted porous sponge matrix;
compressing said wetted sponge matrix; and drying said sponge matrix to form a dry, compressed sponge matrix.
21. The method of claim 20, wherein said sponge matrix is formed from matrix-forming material including collagen.
22. The method of claim 20, wherein said dry sponge matrix is expansible at least about 100% by volume when saturated with deionized water.
23. The method of claim 21, wherein said dry sponge matrix is expansible at least about 100% by volume when saturated with deionized water.
24. The method of claim 23, wherein said dry, compressed sponge matrix has a density of least about 0.05g/cm3.
25. The method of claim 24, wherein said dry, compressed sponge matrix has a density in the range of about 0.05g/cm3 to about 0.2g/cm3.
26. The method of claim 25, wherein said sponge matrix comprises at least one active biotropic agent.
27. The method of claim 20, wherein said sponge matrix comprises collagen from an extracellular matrix.
28. The method of claim 27, wherein said sponge matrix comprises at least one active biotropic agent from said extracellular matrix.
29. The method of claim 28, wherein said extracellular matrix is submucosa or basement membrane.
30. The method of claim 20, wherein said sponge matrix is crosslinked.
31. The method of claim 30, wherein said sponge matrix is crosslinked with a chemical crosslinking agent providing polar groups in the matrix.
32. The method of claim 31, wherein said crosslinking agent is a polyepoxide compound.
33. The method of claim 32, wherein said polyexpoxide compound is a polyglycidyl ether compound.
34. A device useful for providing hemostasis in a tissue biopsy site, comprising:
an element formed from a dry sponge matrix and configured for percutaneous delivery to the biopsy site, said sponge matrix stabilized in a compressed configuration and expansible when wetted.
35. The device of claim 34, wherein said sponge matrix comprises collagen and is crosslinked.
36. The device of claim 35, wherein said sponge matrix is crosslinked with a chemical crosslinking agent providing polar groups in the matrix.
37. The device of claim 36, wherein the chemical crosslinking agent is a polyepoxide compound.
38. The device of claim 37, wherein the polyepoxide compound is a polyglycidyl ether compound.
39. The device of claim 35, wherein said dry sponge matrix has a density of at least about 0.05 g/cm3 and is expansible at least 100% by volume when wetted.
40. A sponge device, comprising:
a dry, compressed sponge matrix defining pores, said sponge matrix having a density of at least about 0.05 g/cm3 and expansible at least about 100% by volume when saturated with deionized water.
41. A method for providing hemostasis in a biopsy site from which a biopsy tissue sample has been taken, comprising implanting in the biopsy tract a hemostatic element formed from a dry sponge matrix stabilized in a compressed configuration. and expansible when wetted.
42. The method of claim 41, wherein said implanting is conducted percutaneously.
43. The method of claim 42, wherein said percutaneously implanting comprises delivering said hemostatic element through a cannula used in obtaining the biopsy tissue sample.
44. A tissue biopsy method, comprising:
inserting a cannula to extend to a tissue site for biopsy, said cannula having an associated cutting member for cutting a sample of tissue from the tissue site;

cutting the sample of tissue with said cutting member;
extracting the sample of tissue through said cannula; and delivering to the tissue site through the cannula a hemostatic element formed from a dry sponge matrix stabilized in a compressed configuration and expansible when wetted.
45. The method of claim 44, wherein said cannula comprises a needle cannula.
CA2452040A 2001-06-29 2002-06-28 Porous sponge matrix medical devices and methods Expired - Fee Related CA2452040C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30224501P 2001-06-29 2001-06-29
US60/302,245 2001-06-29
PCT/US2002/020462 WO2003002168A1 (en) 2001-06-29 2002-06-28 Porous sponge matrix medical devices and methods

Publications (2)

Publication Number Publication Date
CA2452040A1 true CA2452040A1 (en) 2003-01-09
CA2452040C CA2452040C (en) 2011-03-22

Family

ID=23166916

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2452040A Expired - Fee Related CA2452040C (en) 2001-06-29 2002-06-28 Porous sponge matrix medical devices and methods

Country Status (5)

Country Link
US (1) US8877233B2 (en)
EP (1) EP1404390B1 (en)
AU (1) AU2002320182B2 (en)
CA (1) CA2452040C (en)
WO (1) WO2003002168A1 (en)

Families Citing this family (107)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7597715B2 (en) 2005-04-21 2009-10-06 Biomet Manufacturing Corp. Method and apparatus for use of porous implants
US8123814B2 (en) 2001-02-23 2012-02-28 Biomet Manufacturing Corp. Method and appartus for acetabular reconstruction
US20030088240A1 (en) * 2001-11-02 2003-05-08 Vahid Saadat Methods and apparatus for cryo-therapy
US7550004B2 (en) * 2002-08-20 2009-06-23 Cook Biotech Incorporated Endoluminal device with extracellular matrix material and methods
US8709038B2 (en) * 2002-12-20 2014-04-29 Boston Scientific Scimed, Inc. Puncture hole sealing device
US20040122349A1 (en) 2002-12-20 2004-06-24 Lafontaine Daniel M. Closure device with textured surface
US7942897B2 (en) 2003-07-10 2011-05-17 Boston Scientific Scimed, Inc. System for closing an opening in a body cavity
US7537788B2 (en) 2003-07-25 2009-05-26 Rubicor Medical, Inc. Post-biopsy cavity treatment implants and methods
US20050020899A1 (en) 2003-07-25 2005-01-27 Rubicor Medical, Inc. Post-biopsy cavity treatmetn implants and methods
US7744852B2 (en) 2003-07-25 2010-06-29 Rubicor Medical, Llc Methods and systems for marking post biopsy cavity sites
US7645229B2 (en) * 2003-09-26 2010-01-12 Armstrong David N Instrument and method for endoscopic visualization and treatment of anorectal fistula
AU2004294990B2 (en) 2003-11-28 2010-11-11 Cook Biotech Incorporated Vascular occlusion methods, systems and devices
JP5080087B2 (en) * 2004-01-21 2012-11-21 クック メディカル テクノロジーズ エルエルシー Implantable graft to close the heel
AU2005212334B2 (en) 2004-02-09 2011-06-16 Cook Medical Technologies Llc Stent graft devices having collagen coating
US20080089933A1 (en) 2006-10-16 2008-04-17 Amir Alon Device and method for reducing calorie intake
GB2451785B (en) 2004-03-29 2009-03-25 Cook Biotech Inc Medical graft products with differing regions
WO2006026744A1 (en) * 2004-08-31 2006-03-09 Cook Incorporated Device for treating an aneurysm
WO2006062862A1 (en) * 2004-12-06 2006-06-15 Cook Incorporated Inflatable occlusion devices, methods, and systems
EP1833384B1 (en) * 2004-12-30 2017-08-16 Cook Medical Technologies LLC Inverting occlusion devices and systems
US9138445B2 (en) * 2005-03-09 2015-09-22 Cook Biotech Incorporated Medical graft materials with adherent extracellular matrix fibrous mass
US8292967B2 (en) * 2005-04-21 2012-10-23 Biomet Manufacturing Corp. Method and apparatus for use of porous implants
US8066778B2 (en) * 2005-04-21 2011-11-29 Biomet Manufacturing Corp. Porous metal cup with cobalt bearing surface
US8266780B2 (en) * 2005-04-21 2012-09-18 Biomet Manufacturing Corp. Method and apparatus for use of porous implants
US8021432B2 (en) 2005-12-05 2011-09-20 Biomet Manufacturing Corp. Apparatus for use of porous implants
JP4995811B2 (en) 2005-04-29 2012-08-08 クック・バイオテック・インコーポレーテッド Acupuncture positive displacement implants and related methods and systems
US9788821B2 (en) * 2005-04-29 2017-10-17 Cook Biotech Incorporated Physically modified extracellular matrix materials and uses thereof
AU2006270499B2 (en) * 2005-04-29 2011-10-06 Cook Biotech Incorporated Fistula graft with deformable sheet-form material
US7897167B2 (en) * 2005-06-21 2011-03-01 Cook Incorporated Implantable graft to close a fistula
CN1903144A (en) * 2005-07-29 2007-01-31 广东冠昊生物科技有限公司 Biological artificial ligamentum and method for preparing same
CN1903143A (en) * 2005-07-29 2007-01-31 广东冠昊生物科技有限公司 Biological type artificial blood vessel and method for preparing the same
CN100482178C (en) * 2005-08-04 2009-04-29 广东冠昊生物科技有限公司 Blood vessel tumor clip with biological film
US8057495B2 (en) * 2005-09-13 2011-11-15 Cook Medical Technologies Llc Aneurysm occlusion device
WO2007064819A2 (en) * 2005-12-02 2007-06-07 Cook Incorporated Devices, systems, and methods for occluding a defect
CN1986007B (en) * 2005-12-20 2011-09-14 广东冠昊生物科技股份有限公司 Biological surgical patch
CN1985778B (en) * 2005-12-20 2010-10-13 广东冠昊生物科技股份有限公司 Artificial biological cornea
CN1986006A (en) * 2005-12-20 2007-06-27 广州知光生物科技有限公司 Biological nerve duct
CN1986001B (en) * 2005-12-20 2011-09-14 广东冠昊生物科技股份有限公司 Biological wound-protecting film
GB2479480B (en) * 2006-01-31 2012-03-14 Cook Biotech Inc Fistula grafts and related methods and systems for treating fistulae
US7635447B2 (en) * 2006-02-17 2009-12-22 Biomet Manufacturing Corp. Method and apparatus for forming porous metal implants
US9307995B2 (en) * 2006-06-15 2016-04-12 Cook Medical Technologies Llc Methods, systems and devices for the delivery of endoluminal prostheses
AU2007260914B2 (en) * 2006-06-21 2012-11-29 Cook Biotech Incorporated Fistula grafts and related methods and systems useful for treating gastrointestinal fistulae
CN101332314B (en) * 2008-07-22 2012-11-14 广东冠昊生物科技股份有限公司 Biotype articular cartilage repair piece
CN101332316B (en) * 2008-07-22 2012-12-26 广东冠昊生物科技股份有限公司 Biotype nose bridge implantation body
US20100023129A1 (en) * 2008-07-22 2010-01-28 Guo-Feng Xu Jawbone prosthesis and method of manufacture
CA2661527C (en) * 2006-08-24 2011-11-01 Wilson-Cook Medical Inc. Devices and methods for occluding a fistula
US8343536B2 (en) 2007-01-25 2013-01-01 Cook Biotech Incorporated Biofilm-inhibiting medical products
WO2008124361A2 (en) * 2007-04-06 2008-10-16 Cook Biotech Incorporated Fistula plugs having increased column strength and fistula plug delivery apparatuses and methods
US20080279833A1 (en) * 2007-05-10 2008-11-13 Matheny Robert G Laminate sheet articles for tissue regeneration
US8932619B2 (en) 2007-06-27 2015-01-13 Sofradim Production Dural repair material
US20090004455A1 (en) * 2007-06-27 2009-01-01 Philippe Gravagna Reinforced composite implant
US8535349B2 (en) * 2007-07-02 2013-09-17 Cook Biotech Incorporated Fistula grafts having a deflectable graft body portion
DE102007037053A1 (en) * 2007-07-24 2009-01-29 Aesculap Ag Hemostatic for minimally invasive surgery
US9113851B2 (en) 2007-08-23 2015-08-25 Cook Biotech Incorporated Fistula plugs and apparatuses and methods for fistula plug delivery
US20090068250A1 (en) 2007-09-07 2009-03-12 Philippe Gravagna Bioresorbable and biocompatible compounds for surgical use
US20090069843A1 (en) * 2007-09-10 2009-03-12 Agnew Charles W Fistula plugs including a hydration resistant component
WO2009036250A1 (en) 2007-09-12 2009-03-19 Cook Incorporated Enhanced remodelable materials for occluding bodily vessels and related methods and systems
JP5205462B2 (en) * 2007-09-25 2013-06-05 バイオメット・マニュファクチャリング・コーポレイション Cementless tibial tray
US9308068B2 (en) * 2007-12-03 2016-04-12 Sofradim Production Implant for parastomal hernia
US8956378B2 (en) * 2008-02-29 2015-02-17 Cook Biotech Incorporated Coated embolization device
GB2471632B (en) 2008-05-02 2012-04-18 Cook Biotech Inc Self deploying SIS in needle
DE112009001300T5 (en) * 2008-05-29 2011-04-14 Cook Biotech, Inc., West Lafayette Devices and methods for the treatment of rectovaginal and other fistulas
US9295757B2 (en) 2008-06-10 2016-03-29 Cook Biotech Incorporated Quilted implantable graft
CN102056634B (en) * 2008-06-10 2015-11-25 库克生物科技公司 Quilted implantable graft
CN102112162B (en) * 2008-06-20 2014-12-24 库克生物科技公司 Composite extracellular matrix materials and medical products formed therefrom
US9242026B2 (en) 2008-06-27 2016-01-26 Sofradim Production Biosynthetic implant for soft tissue repair
EP2427157B1 (en) * 2009-05-04 2019-03-13 Oregon Biomedical Engineering Institute, Inc. Hemorrhage control devices and methods
US8652500B2 (en) 2009-07-22 2014-02-18 Acell, Inc. Particulate tissue graft with components of differing density and methods of making and using the same
FR2949688B1 (en) 2009-09-04 2012-08-24 Sofradim Production FABRIC WITH PICOTS COATED WITH A BIORESORBABLE MICROPOROUS LAYER
WO2012050836A1 (en) 2010-09-28 2012-04-19 Cook Biotech Incorporated Devices and methods for treating fistulae and other bodily openings and passageways
FR2972626B1 (en) 2011-03-16 2014-04-11 Sofradim Production PROSTHETIC COMPRISING A THREE-DIMENSIONAL KNIT AND ADJUSTED
WO2012170538A2 (en) 2011-06-06 2012-12-13 Cook Medical Technologies Llc Vascular occlusion devices and methods
WO2012174234A2 (en) 2011-06-14 2012-12-20 Cook Medical Technologies Llc Fistula closure devices and methods
FR2977790B1 (en) 2011-07-13 2013-07-19 Sofradim Production PROSTHETIC FOR UMBILIC HERNIA
FR2977789B1 (en) 2011-07-13 2013-07-19 Sofradim Production PROSTHETIC FOR UMBILIC HERNIA
WO2013046058A2 (en) 2011-09-30 2013-04-04 Sofradim Production Reversible stiffening of light weight mesh
EP2760431A1 (en) 2011-09-30 2014-08-06 Sofradim Production Multilayer implants for delivery of therapeutic agents
FR2985271B1 (en) 2011-12-29 2014-01-24 Sofradim Production KNITTED PICOTS
FR2985170B1 (en) 2011-12-29 2014-01-24 Sofradim Production PROSTHESIS FOR INGUINAL HERNIA
US10130346B2 (en) * 2012-07-24 2018-11-20 Omrix Biopharmaceuticals Ltd. Device and method for the application of a curable fluid composition to a bodily organ
FR2994185B1 (en) 2012-08-02 2015-07-31 Sofradim Production PROCESS FOR THE PREPARATION OF A POROUS CHITOSAN LAYER
FR2995788B1 (en) 2012-09-25 2014-09-26 Sofradim Production HEMOSTATIC PATCH AND PREPARATION METHOD
FR2995779B1 (en) 2012-09-25 2015-09-25 Sofradim Production PROSTHETIC COMPRISING A TREILLIS AND A MEANS OF CONSOLIDATION
FR2995778B1 (en) 2012-09-25 2015-06-26 Sofradim Production ABDOMINAL WALL REINFORCING PROSTHESIS AND METHOD FOR MANUFACTURING THE SAME
US10159555B2 (en) 2012-09-28 2018-12-25 Sofradim Production Packaging for a hernia repair device
USD754325S1 (en) 2013-06-06 2016-04-19 Omrix Biopharmaceuticals Ltd. Device of a curable fluid composition to a bodily organ
FR3006578B1 (en) 2013-06-07 2015-05-29 Sofradim Production PROSTHESIS BASED ON TEXTILE FOR LAPAROSCOPIC PATHWAY
FR3006581B1 (en) 2013-06-07 2016-07-22 Sofradim Production PROSTHESIS BASED ON TEXTILE FOR LAPAROSCOPIC PATHWAY
EP3169248B1 (en) 2014-07-20 2021-03-31 Riina, Howard, Anthony Device for surgical suturing
EP3000489B1 (en) 2014-09-24 2017-04-05 Sofradim Production Method for preparing an anti-adhesion barrier film
EP3000433B1 (en) 2014-09-29 2022-09-21 Sofradim Production Device for introducing a prosthesis for hernia treatment into an incision and flexible textile based prosthesis
EP3000432B1 (en) 2014-09-29 2022-05-04 Sofradim Production Textile-based prosthesis for treatment of inguinal hernia
EP3029189B1 (en) 2014-12-05 2021-08-11 Sofradim Production Prosthetic porous knit, method of making same and hernia prosthesis
US9238090B1 (en) 2014-12-24 2016-01-19 Fettech, Llc Tissue-based compositions
EP3059255B1 (en) 2015-02-17 2020-05-13 Sofradim Production Method for preparing a chitosan-based matrix comprising a fiber reinforcement member
JP6527244B2 (en) * 2015-03-26 2019-06-05 ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． Biobased Expandable Occlusion Device, Assembly, and Kit
EP3085337B1 (en) 2015-04-24 2022-09-14 Sofradim Production Prosthesis for supporting a breast structure
ES2676072T3 (en) 2015-06-19 2018-07-16 Sofradim Production Synthetic prosthesis comprising a knitted fabric and a non-porous film and method of forming it
EP3195830B1 (en) 2016-01-25 2020-11-18 Sofradim Production Prosthesis for hernia repair
US20170245570A1 (en) * 2016-02-25 2017-08-31 William Yuen Smart garment
WO2018051205A1 (en) * 2016-09-16 2018-03-22 Universidad De Los Andes Extracellular-matrix haemostatic plug for percutaneous biopsies and device for the production thereof
EP3312325B1 (en) 2016-10-21 2021-09-22 Sofradim Production Method for forming a mesh having a barbed suture attached thereto and the mesh thus obtained
US20180214846A1 (en) * 2017-01-30 2018-08-02 Slendine Ag Matrix materials having mechanically-shaped sponge architecture and methods of preparing thereof
EP3398554A1 (en) 2017-05-02 2018-11-07 Sofradim Production Prosthesis for inguinal hernia repair
CN108714241A (en) * 2018-06-22 2018-10-30 中国人民解放军陆军军医大学第附属医院 Application of the SIS epoxy resins in preparing hemostatic material
EP3653171A1 (en) 2018-11-16 2020-05-20 Sofradim Production Implants suitable for soft tissue repair
CN110975010B (en) * 2019-11-25 2022-02-15 银丰低温医学科技有限公司 Placenta tissue matrix material and preparation method thereof
CN113289063A (en) * 2021-05-27 2021-08-24 江阴市人民医院 Biological material for soft tissue repair and preparation method thereof

Family Cites Families (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB887844A (en) 1958-11-13 1962-01-24 John Straythorn Robins Surgical dressing
US3566871A (en) * 1968-06-11 1971-03-02 American Cyanamid Co Hydrophilic medical sponge and method of using same
US3823212A (en) * 1968-11-27 1974-07-09 Freudenberg C Fa Process for the production of collagen fiber fabrics in the form of felt-like membranes or sponge-like layers
US3810473A (en) * 1972-12-04 1974-05-14 Avicon Inc Liquid-laid, non-woven, fibrous collagen derived surgical web having hemostatic and wound sealing properties
US4193813A (en) * 1976-09-07 1980-03-18 Medi-Coll, Inc. Method for making collagen sponge
US4271835A (en) * 1978-05-17 1981-06-09 Kcdp Corporation Fluid-expansible contraceptive tampon and applicator
FR2516927B1 (en) 1981-11-26 1986-05-23 Merieux Fond PROCESS FOR THE INDUSTRIAL PREPARATION OF COLLAGENIC MATERIALS FROM HUMAN PLACENTARY TISSUES, HUMAN COLLAGENIC MATERIALS OBTAINED, THEIR APPLICATION AS BIOMATERIALS
US4578067A (en) * 1982-04-12 1986-03-25 Alcon (Puerto Rico) Inc. Hemostatic-adhesive, collagen dressing for severed biological surfaces
CA1295796C (en) * 1984-03-27 1992-02-18 Conrad Whyne Biodegradable matrix and methods for producing same
US4852568A (en) * 1987-02-17 1989-08-01 Kensey Nash Corporation Method and apparatus for sealing an opening in tissue of a living being
US4846793A (en) * 1987-03-18 1989-07-11 Endocon, Inc. Injector for implanting multiple pellet medicaments
US5219576A (en) * 1988-06-30 1993-06-15 Collagen Corporation Collagen wound healing matrices and process for their production
US4956178A (en) * 1988-07-11 1990-09-11 Purdue Research Foundation Tissue graft composition
US4902508A (en) 1988-07-11 1990-02-20 Purdue Research Foundation Tissue graft composition
US5391183A (en) * 1990-09-21 1995-02-21 Datascope Investment Corp Device and method sealing puncture wounds
US5108421A (en) * 1990-10-01 1992-04-28 Quinton Instrument Company Insertion assembly and method of inserting a vessel plug into the body of a patient
US5206028A (en) * 1991-02-11 1993-04-27 Li Shu Tung Dense collagen membrane matrices for medical uses
GR920100122A (en) * 1991-04-05 1993-03-16 Ethicon Inc Ionically crosslinked carboxyl-containing polysaccharides for adhension prevention.
US5326350A (en) * 1992-05-11 1994-07-05 Li Shu Tung Soft tissue closure systems
US5279555A (en) * 1992-08-24 1994-01-18 Merck & Co., Inc. Device for injecting implants
WO1994006460A1 (en) * 1992-09-21 1994-03-31 Vitaphore Corporation Embolization plugs for blood vessels
US5334216A (en) * 1992-12-10 1994-08-02 Howmedica Inc. Hemostatic plug
US5388588A (en) * 1993-05-04 1995-02-14 Nabai; Hossein Biopsy wound closure device and method
US5325857A (en) * 1993-07-09 1994-07-05 Hossein Nabai Skin biopsy device and method
US5394886A (en) * 1993-09-20 1995-03-07 Nabai; Hossein Skin biopsy plug and method
US6130264A (en) * 1994-10-06 2000-10-10 Xomed Surgical Products, Inc. Synthetic sponge and surgical spear comprising synthetic sponge
US5674298A (en) * 1994-10-21 1997-10-07 The Board Of Regents Of The University Of Michigan Calcification-resistant bioprosthetic tissue and methods of making same
US5554389A (en) * 1995-04-07 1996-09-10 Purdue Research Foundation Urinary bladder submucosa derived tissue graft
US6071301A (en) * 1998-05-01 2000-06-06 Sub Q., Inc. Device and method for facilitating hemostasis of a biopsy tract
US6183497B1 (en) * 1998-05-01 2001-02-06 Sub-Q, Inc. Absorbable sponge with contrasting agent
DE69725592T2 (en) * 1996-08-23 2004-08-05 Cook Biotech, Inc., West Lafayette METHOD FOR OBTAINING A SUITABLE COLLAGEN-BASED MATRIX FROM SUBMUKOSA TISSUE
ES2208761T3 (en) * 1996-09-07 2004-06-16 Gunther Beisel PRODUCT WITH DELAYING EFFECT.
US5782914A (en) * 1996-11-29 1998-07-21 Bio-Vascular, Inc. Method for preparing heterogeneous tissue grafts
CA2274033C (en) 1996-12-10 2010-05-11 Purdue Research Foundation Biomaterial derived from vertebrate liver tissue
DE69720252T2 (en) * 1996-12-10 2003-12-04 Purdue Research Foundation West Lafayette TISSUE TRANSPLANT FROM THE MAGIC SUBMUCOSA
DE19739031A1 (en) * 1997-09-05 1999-03-11 Suwelack Nachf Dr Otto Oral administration agent, its preparation and use
US6270464B1 (en) * 1998-06-22 2001-08-07 Artemis Medical, Inc. Biopsy localization method and device
US6008292A (en) * 1997-12-02 1999-12-28 Baxter International Inc. Method for inhibiting calcification of aldehyde-fixed bioprosthetic materials
NZ525373A (en) * 1997-12-29 2004-12-24 Alza Corp Implanter device for subcutaneous implants with retractable cannula to release implant
US20010045575A1 (en) 1998-05-01 2001-11-29 Mark Ashby Device and method for facilitating hemostasis of a biopsy tract
US6056970A (en) * 1998-05-07 2000-05-02 Genzyme Corporation Compositions comprising hemostatic compounds and bioabsorbable polymers
US6183496B1 (en) * 1998-11-02 2001-02-06 Datascope Investment Corp. Collapsible hemostatic plug
AU4316399A (en) 1998-12-01 2000-06-19 Cook Biotech, Inc. A multi-formed collagenous biomaterial medical device
US6371904B1 (en) * 1998-12-24 2002-04-16 Vivant Medical, Inc. Subcutaneous cavity marking device and method
US6977231B1 (en) 1999-01-21 2005-12-20 Nipro Corporation Suturable adhesion-preventing membrane
DE20105763U1 (en) * 2001-04-02 2001-07-19 Roehm Gmbh Drill chuck with a quick coupling
US6605047B2 (en) * 2001-09-10 2003-08-12 Vivant Medical, Inc. Biopsy marker delivery system

Also Published As

Publication number Publication date
EP1404390B1 (en) 2012-08-01
EP1404390A1 (en) 2004-04-07
WO2003002168A1 (en) 2003-01-09
CA2452040C (en) 2011-03-22
AU2002320182B2 (en) 2008-02-21
US20030013989A1 (en) 2003-01-16
US8877233B2 (en) 2014-11-04

Similar Documents

Publication Publication Date Title
CA2452040A1 (en) Porous sponge matrix medical devices and methods
AU2002320182A1 (en) Porous sponge matrix medical devices and methods
EP2175389A3 (en) Method of non-targeted complex sample analysis
JP5898399B2 (en) Absorption-replacement type artificial bone and manufacturing method thereof
CN105561375B (en) A kind of gelatin liquid-absorbent hemostatic sponge and preparation method thereof of dopamine crosslinking
JP2010158516A (en) Artificial bone capable of being absorbed and replaced by autogenous bone and production method for producing the same
EP0624074A1 (en) Electrode
WO2007070681A3 (en) Pliable medical device and method of use
CN110841112A (en) Method for producing decellularized tissue product, and graft having decellularized tissue product
DE60038315T2 (en) NEW MATERIAL ON Collagen BASE WITH IMPROVED PROPERTIES FOR USE IN HUMAN AND VETERINARY MEDICINE AND A MANUFACTURING PROCESS
CN103234797A (en) Dehydrating and embedding improvement method of human body or animal tissues
CN107596438B (en) A kind of natural polysaccharide self-healing hydrogel of injectable and the preparation method and application thereof
CN108478877A (en) Bionical chitosan/oxidized graphene compound osseous tissue engineering timbering material of orientation and preparation method thereof
Rahm Jr et al. LXXIII The Effects of Topical Anesthetics upon the Ear
KR101004781B1 (en) Method and device for wetting a medical implant or transplant
EP2198895A3 (en) Porous structures of microbial-derived cellulose for in vivo implantation
CN101530402A (en) Silk fibroin multicoat membrane and preparation method thereof
US9724075B2 (en) Biopsy method and apparatus
US20230132953A1 (en) Plug for lung tissue tract sealing
KR20220018481A (en) Tissue-derived porous matrix and method of making and using the same
CN203898797U (en) Hydrophilic and hydrophobic agarose collagen dressing
WO1991019480A1 (en) Pharmaceutical preparation
CN101765935B (en) Fuel cell and fuel cell system
CN208710260U (en) A kind of unidirectional osmosis dehydrated hydrogel film
CN214209030U (en) Nasal cavity hemostatic cotton with pore diameter gradient distribution

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed