CA2440854A1 - Subcutaneous analyte sensor - Google Patents

Subcutaneous analyte sensor Download PDF

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Publication number
CA2440854A1
CA2440854A1 CA002440854A CA2440854A CA2440854A1 CA 2440854 A1 CA2440854 A1 CA 2440854A1 CA 002440854 A CA002440854 A CA 002440854A CA 2440854 A CA2440854 A CA 2440854A CA 2440854 A1 CA2440854 A1 CA 2440854A1
Authority
CA
Canada
Prior art keywords
light
cavity
analyte
membrane
intensities
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002440854A
Other languages
French (fr)
Other versions
CA2440854C (en
Inventor
Matthias Essenpreis
Martin Gerber
Wolfgang Petrich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F. Hoffmann-La Roche Ag
Matthias Essenpreis
Martin Gerber
Wolfgang Petrich
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F. Hoffmann-La Roche Ag, Matthias Essenpreis, Martin Gerber, Wolfgang Petrich filed Critical F. Hoffmann-La Roche Ag
Publication of CA2440854A1 publication Critical patent/CA2440854A1/en
Application granted granted Critical
Publication of CA2440854C publication Critical patent/CA2440854C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/1459—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters invasive, e.g. introduced into the body by a catheter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement

Abstract

Assembly and method for measuring the concentration of an analyte in a biological matrix. The assembly includes an implantable optical-sensing element that comprises a body, and a membrane mounted on the body in a manner such that the membrane and the body define a cavity. The membrane is permeable to the analyte, but is impermeable to background species in the biological matrix. A refractive element is positioned in the cavity. A light source transmits light of a first intensity onto the refractive element, and a light detector receives light of a second intensity that is reflected from the cavity. A controller device optically coupled to the detector compares the first and second light intensities, and relates the intensities to analyte concentration.
CA 2440854 2001-03-16 2002-03-18 Subcutaneous analyte sensor Expired - Fee Related CA2440854C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/810,635 2001-03-16
US09/810,635 US6952603B2 (en) 2001-03-16 2001-03-16 Subcutaneous analyte sensor
PCT/EP2002/002960 WO2002074161A2 (en) 2001-03-16 2002-03-18 Subcutaneous analyte sensor

Publications (2)

Publication Number Publication Date
CA2440854A1 true CA2440854A1 (en) 2002-09-26
CA2440854C CA2440854C (en) 2008-08-05

Family

ID=25204303

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2440854 Expired - Fee Related CA2440854C (en) 2001-03-16 2002-03-18 Subcutaneous analyte sensor

Country Status (6)

Country Link
US (3) US6952603B2 (en)
EP (1) EP1372466A2 (en)
JP (1) JP3692116B2 (en)
AU (1) AU2002237332A1 (en)
CA (1) CA2440854C (en)
WO (1) WO2002074161A2 (en)

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