CA2430917C - Drive mechanism for an injection device - Google Patents
Drive mechanism for an injection device Download PDFInfo
- Publication number
- CA2430917C CA2430917C CA002430917A CA2430917A CA2430917C CA 2430917 C CA2430917 C CA 2430917C CA 002430917 A CA002430917 A CA 002430917A CA 2430917 A CA2430917 A CA 2430917A CA 2430917 C CA2430917 C CA 2430917C
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- gear means
- gear
- drive mechanism
- drive
- housing
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
- A61M5/14566—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons with a replaceable reservoir for receiving a piston rod of the pump
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
- G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
- G16H20/17—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M2005/31588—Constructional features or modes of drive mechanisms for piston rods electrically driven
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/21—General characteristics of the apparatus insensitive to tilting or inclination, e.g. spill-over prevention
- A61M2205/215—Tilt detection, e.g. for warning or shut-off
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/50—General characteristics of the apparatus with microprocessors or computers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/60—General characteristics of the apparatus with identification means
- A61M2205/6018—General characteristics of the apparatus with identification means providing set-up signals for the apparatus configuration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/82—Internal energy supply devices
- A61M2205/8206—Internal energy supply devices battery-operated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31525—Dosing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31546—Electrically operated dose setting, e.g. input via touch screen or plus/minus buttons
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S128/00—Surgery
- Y10S128/01—Motorized syringe
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Medical Informatics (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Primary Health Care (AREA)
- Chemical & Material Sciences (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Fuel-Injection Apparatus (AREA)
- Read Only Memory (AREA)
- Knitting Machines (AREA)
- Electrical Control Of Air Or Fuel Supplied To Internal-Combustion Engine (AREA)
- External Artificial Organs (AREA)
- Apparatus For Radiation Diagnosis (AREA)
- Chemical Or Physical Treatment Of Fibers (AREA)
- Electrophonic Musical Instruments (AREA)
- Polarising Elements (AREA)
- Diaphragms For Electromechanical Transducers (AREA)
- Coating Apparatus (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Seal Device For Vehicle (AREA)
- Vehicle Body Suspensions (AREA)
- Valve Device For Special Equipments (AREA)
- Elimination Of Static Electricity (AREA)
- Loading And Unloading Of Fuel Tanks Or Ships (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
- Medicinal Preparation (AREA)
- Disintegrating Or Milling (AREA)
Abstract
A drive mechanism for an injection device is disclosed in which piston means are selectively driven to expel medicament from within a medicament cartridge.
The drive mechanism comprises a drive means (270), first means (278) associated with the drive means, second gear means (274) being moveable between a first position in wich only movement along its longitudinal axis is permitted and a second position in which the second gear means (274) is free to rotate about the longitudinal axis, the piston means (280) being associated with the second gear means (274), a housing (276) within which the first gear means (278) and the second gear means (274) are constrained for movement, and baissing means (282) located between the housing (276) and second gear means (274) to bias the second gear means (274) to the first position.
The drive mechanism comprises a drive means (270), first means (278) associated with the drive means, second gear means (274) being moveable between a first position in wich only movement along its longitudinal axis is permitted and a second position in which the second gear means (274) is free to rotate about the longitudinal axis, the piston means (280) being associated with the second gear means (274), a housing (276) within which the first gear means (278) and the second gear means (274) are constrained for movement, and baissing means (282) located between the housing (276) and second gear means (274) to bias the second gear means (274) to the first position.
Description
DRIVE MECHANISM FOR .AN INJECTION DEVICE
The present invention relates to improvements in an injection device, and in particular to improvements in a portable injection device for dispensing controlled quantities of a medicament.
Typically such injection devices are used by those suffering from diabetes to administer a dose of insulin or insulin-type medicine to themselves. It will be understood that such injection devices are suitable for the injection of other medicines.
1o At one time, such doses were administered by use of a disposable syringe; the syringe first being filled from a separate phial or other container and then used to inject the dose.
However, there were a number of difficulties in such an arrangement. In particular, such an arrangement was not suitable for the infirm. For others, the social stigma associated 15 with such syringes made their public use problematic.
To overcome these difficulties a number of so-called pen-type injectors have been developed. These devices are small, being capable of being carried in a jacket pocket or the like and allow a number of doses to be obtained from a cartridge or ampoule 2o contained within the injector. The present invention has particular application to such pen-type injectors.
While such pen-type injectors are a considerable improvement upon disposable hypodermic syringes, problems nevertheless remain.
In particular when considering the design of a drive system for a pen-type injector, there are a number of, sometimes, conflicting technical requirements. The drive system must be accurate and reliable, and at the same time compact and efficient. The drive system must be reliable and robust; being able to function for the life of the product. The drive 3o system must also be intrinsically fail-safe.
The present invention relates to improvements in an injection device, and in particular to improvements in a portable injection device for dispensing controlled quantities of a medicament.
Typically such injection devices are used by those suffering from diabetes to administer a dose of insulin or insulin-type medicine to themselves. It will be understood that such injection devices are suitable for the injection of other medicines.
1o At one time, such doses were administered by use of a disposable syringe; the syringe first being filled from a separate phial or other container and then used to inject the dose.
However, there were a number of difficulties in such an arrangement. In particular, such an arrangement was not suitable for the infirm. For others, the social stigma associated 15 with such syringes made their public use problematic.
To overcome these difficulties a number of so-called pen-type injectors have been developed. These devices are small, being capable of being carried in a jacket pocket or the like and allow a number of doses to be obtained from a cartridge or ampoule 2o contained within the injector. The present invention has particular application to such pen-type injectors.
While such pen-type injectors are a considerable improvement upon disposable hypodermic syringes, problems nevertheless remain.
In particular when considering the design of a drive system for a pen-type injector, there are a number of, sometimes, conflicting technical requirements. The drive system must be accurate and reliable, and at the same time compact and efficient. The drive system must be reliable and robust; being able to function for the life of the product. The drive 3o system must also be intrinsically fail-safe.
2 It is an advantage of the present invention that it eliminates, or at least substantially reduces such problems. The present invention also provides for improved ease of use and improved interaction with a user.
The invention will now be described, by way of example only, with reference to the accompanying drawings; in which:-Figure 1 shows a plan view of a pen-type injector in accordance with the present invention;
to Figure 2 shows a similar view to Figure 1 with an end cap of the injector omitted;
Figure 3 shows a cross-sectional view of the injector of Figures 1 and 2;
Figures 4 to 6 show in plan view a part of a still further drive mechanism through three stages of operation.
15 Refernng first to Figures 1 to 3, there can be seen a pen-type injector 2 in accordance with the present invention. The injector 2 comprises a main housing 4 to which is releasably secured an end cap or cover 6.
At a first end of the main housing 4 there is provided a control panel region 8. This 2o region includes a display panel 10, typically a LCD display, and a first dose button 12 and a second dose button 14, the first and second dose buttons being operated to increase or decrease a dose of medicament to be delivered. The control panel region 10 in the illustrated embodiment also includes an arm button 16.
25 At the first end of the main housing there is also provided a dispense button 18.
Preferably, when not depressed, the dispense button 18 is flush with the main housing 4.
Along a longitudinal axis of the injector 2, to each side of the control panel region 10 are provided a number of grooves or recesses 20. These aid in the gripping of the inj ector 2 30 by a user.
The invention will now be described, by way of example only, with reference to the accompanying drawings; in which:-Figure 1 shows a plan view of a pen-type injector in accordance with the present invention;
to Figure 2 shows a similar view to Figure 1 with an end cap of the injector omitted;
Figure 3 shows a cross-sectional view of the injector of Figures 1 and 2;
Figures 4 to 6 show in plan view a part of a still further drive mechanism through three stages of operation.
15 Refernng first to Figures 1 to 3, there can be seen a pen-type injector 2 in accordance with the present invention. The injector 2 comprises a main housing 4 to which is releasably secured an end cap or cover 6.
At a first end of the main housing 4 there is provided a control panel region 8. This 2o region includes a display panel 10, typically a LCD display, and a first dose button 12 and a second dose button 14, the first and second dose buttons being operated to increase or decrease a dose of medicament to be delivered. The control panel region 10 in the illustrated embodiment also includes an arm button 16.
25 At the first end of the main housing there is also provided a dispense button 18.
Preferably, when not depressed, the dispense button 18 is flush with the main housing 4.
Along a longitudinal axis of the injector 2, to each side of the control panel region 10 are provided a number of grooves or recesses 20. These aid in the gripping of the inj ector 2 30 by a user.
3 At a second end of the main housing 4 a needle unit 22 is releasably secured to the main housing. The second end of the main housing 4 is also provided with a shaped portion 24.
In use a cartridge 40 or ampoule of medicament is stored in the housing 4 behind the shaped portion 24. For preference, the shaped portion is transparent to permit the cartridge 40 to be seen by a user.
to A primer button 26 is also provided on the second end of the housing 4. It will be understood that when the end cap 6 is in place over the second end of the housing, it will not be possible inadvertently to depress the primer button 26 or to be pricked by the needle unit 22. A cover detection switch 28 may also be included at the second end of the main housing 4 to detect whether the end cap or cover 6 is in place or not.
In Figure 3, there can be seen a priming contact 30, an arm contact 32, a first dose contact 34 and a second dose contact 36 corresponding to the respective buttons. A
dispense contact 19 corresponding to the dispense button 18 is also shown.
2o With reference to Figure 3 it may be seen that there is provided a suitable location for a power source 38 such as a battery or batteries. There is also a suitable region in which a cartridge 40 or ampoule of medicament is to be located. This region may be accessed by way of the removable shaped portion 24 of the main housing 4 to allow for replacement of the cartridge 40 or ampoule as required by the user.
In a third region of the main housing 4 there is provided a drive mechanism 42 which operates from the power source 38 and acts upon the cartridge 40 or ampoule of medicament.
In use a cartridge 40 or ampoule of medicament is stored in the housing 4 behind the shaped portion 24. For preference, the shaped portion is transparent to permit the cartridge 40 to be seen by a user.
to A primer button 26 is also provided on the second end of the housing 4. It will be understood that when the end cap 6 is in place over the second end of the housing, it will not be possible inadvertently to depress the primer button 26 or to be pricked by the needle unit 22. A cover detection switch 28 may also be included at the second end of the main housing 4 to detect whether the end cap or cover 6 is in place or not.
In Figure 3, there can be seen a priming contact 30, an arm contact 32, a first dose contact 34 and a second dose contact 36 corresponding to the respective buttons. A
dispense contact 19 corresponding to the dispense button 18 is also shown.
2o With reference to Figure 3 it may be seen that there is provided a suitable location for a power source 38 such as a battery or batteries. There is also a suitable region in which a cartridge 40 or ampoule of medicament is to be located. This region may be accessed by way of the removable shaped portion 24 of the main housing 4 to allow for replacement of the cartridge 40 or ampoule as required by the user.
In a third region of the main housing 4 there is provided a drive mechanism 42 which operates from the power source 38 and acts upon the cartridge 40 or ampoule of medicament.
4 The cartridge 40 or ampoule comprises a container 44 or sleeve closed at one end by a cover 46 at a head end thereof, and sealed at the other by a movable bung 48 or stopper.
When in position, the needle unit 22 pierces the cover 46 and movement of the bung 48 towards the cover 46 will cause the medicament contained within the cartridge 40 or ampoule to be expelled. The cartridge may be a 3m1 cartridge in accordance with ISOIFDIS 11608 Part 3, or any other suitable cartridge to suit the injector.
Movement of the bung 48 or stopper is caused by movement of a piston or plunger 50 forming a part of the drive mechanism 42. The piston or plunger 50 is movable between to a first fully withdrawn position (not shown) which allows for the replacement of the cartridge 40 or ampoule and a second fully extended portion in which as much medicament as possible has been expelled from the cartridge 40 or ampoule. An end stop switch 52 may be provided in the main housing 4 to detect when the piston 50 is in the fully withdrawn position. Tripping of the switch end stop 52 may release a catch or other 15 fastening device to allow access to the main housing 4 for replacement of the cartridge 40.
The drive mechanism 42 is operated by a motor 54 under the control of an electronic control unit (not shown). The motor 54 should be reversible in order to allow the 2o piston 50 to be moved between the first and second positions. In Figure 3, the motor 54 can be seen to drive the piston 50 by way of a gear train 42, such that rotation of a third rotor 58 causes the piston SO to be moved in relation to the third rotor 58.
Preferably, the user can feel the vibration of the motor 54 and the associated drive 25 mechanism 42 and/or hear them in operation. In this way an added degree of confidence in the fact of the operation of the injector 2 is provided to the user.
The functionality of a pen-type injector in accordance with the present invention will now be described, in particular with reference to Figures 1, 2 and 3.
The inj ector 2 is provided with an electronic control unit. The electronic control unit is coupled both to the drive mechanism and a user interface. The user interface includes the display panel 10 as well as the user operable buttons (and associated contacts). The electronic control unit is microprocessor based. Either volatile or non-volatile memory may be used for storage of 'dose history' and patient specific information.
The electronic control unit is preferably powered from the inj ector power source 3 ~.
The inj ector 2 preferably also includes a port for communication between the electronic 1o control unit and an external apparatus such as a personal computer.
The injector 2 also has a priming detection facility, (such as a tilt switch or accelerometer) to identify when the injector 2 is inverted. On detection of an inverted position (needle up) the injector 2 will automatically change state to be ready for priming.
Priming may be initiated by depression of the primer button 26 to cause a fixed small dispense action. The electronic control unit may cause a speaker to sound when the primer button 26 is depressed.
The primer button 26 is inactive at all other times. When the primer button 26 is active, 2o all other buttons in the control panel region are inactive, that is those buttons which are to be used to set or dispense a dose.
The electronic control unit may cause a speaker to sound when the arm button 16 is depressed for a sufficient period of time to provide audible feedbaclc for the user.
The function of the arm button 16 is to make the dispense button I8 active.
The arm button is preferably held down for a predetermined period of time before the injector 2 becomes armed. The armed status may additionally be shown on the display panel 10.
The functionality of the arm button is preferably linked to the cover detection switch 28 such that the arm button 16 will only function to arm the inj ector 2 when the cover 6 is not present.
Additionally, in a preferred embodiment, a cloclc within the electronic control unit will detect whether the dispense button 18 has been pressed within a specified time interval following arming of the injector 2. If the dispense button 18 has not been depressed within the specified time interval the electronic control unit will disarm the injector 2.
Alternatively, if the arm button is depressed a second time within a predetermined time period by the user, the injector will be disabled.
In an alternative embodiment, the dispense button I8 may function as both a prime button and the dose button. When the priming detector is actuated, by the injector 2 being oriented needle up, the dispense button 18 would change function to that of the prime button of the previous embodiment.
The buttons of the injector 2 are preferably tactile in nature to provide sensory feedback to the user.
The display panel 10 is typically an LCD display and will provide alphanumeric and 2o graphical information relating to the operation of the device.
Due to the use of an electromechanical drive, the dispense action is initiated by the user operating a switch. This means that the force required to operate the dispense button can be optimised for the comfort and ergonomic requirement of users.
In Figures 4, 5 and 6, there is shown a drive mechanism in the form of a single indexing gear arrangement. A push pull solenoid 270 is shown having an output shaft 272. The output shaft is coupled to a driving gear 278. The driving gear 278 is driven longitudinally within a gear housing 276. A shaft 280 of ~a lead screw is coupled to a 3o driven gear 274. The lead screw will be understood to comprise piston means for the advancement of bung 48 within a medicament cartridge 40 within the context of this description. The driven gear is located for movement longitudinally within the gear housing 276. Spring biassing means, typically a helical spring 282, are located between a rear face of the driven gear 274 and the gear housing 276 to urge the driven gear 274 toward the driving gear 278. Each of the driven gear 274 and the driving gear 278 are provided with angularly disposed teeth such that the teeth of the driven gear 274 may mate with the teeth of the driving gear 278.
The rotation of the driven gear 274 is aided by the presence of keyways (not shown) on the outer diameter of the driven gear 274 which engage with a set of splines (not shown) provided on an internal face of the housing 276. The splines prevent the driven gear 274 from meshing completely with the driving gear 278. As the driving gear advances on a push stroke of the solenoid 270, the driven gear 274 is pushed,.against the spring biassing means 282, along the splines until a point is reached where the driven gear 274 may disengage from the splines. At this point, the driven gear 274 rotates under the combined action of the pushing force of the spring biassing means and that of the solenoid until the teeth of the driven gear 274 and the driving gear 278 mesh (Figure 5).
On a return stroke, the driven gear 274 is returned, under the action of the spring biassing 2o means 282. However, due to the rotation the keyways now pick up the next spline location allowing the driven gear 274 to return to a longitudinal position corresponding to a start position, but angularly offset from the previous start position.
This drive mechanism has a number of advantages. In particular, it has no indeterminate position which might lead to jamming of the drive mechanism. Also, the drive mechanism latches at the end of each stroke, malting accidental dispense unlikely.
When in position, the needle unit 22 pierces the cover 46 and movement of the bung 48 towards the cover 46 will cause the medicament contained within the cartridge 40 or ampoule to be expelled. The cartridge may be a 3m1 cartridge in accordance with ISOIFDIS 11608 Part 3, or any other suitable cartridge to suit the injector.
Movement of the bung 48 or stopper is caused by movement of a piston or plunger 50 forming a part of the drive mechanism 42. The piston or plunger 50 is movable between to a first fully withdrawn position (not shown) which allows for the replacement of the cartridge 40 or ampoule and a second fully extended portion in which as much medicament as possible has been expelled from the cartridge 40 or ampoule. An end stop switch 52 may be provided in the main housing 4 to detect when the piston 50 is in the fully withdrawn position. Tripping of the switch end stop 52 may release a catch or other 15 fastening device to allow access to the main housing 4 for replacement of the cartridge 40.
The drive mechanism 42 is operated by a motor 54 under the control of an electronic control unit (not shown). The motor 54 should be reversible in order to allow the 2o piston 50 to be moved between the first and second positions. In Figure 3, the motor 54 can be seen to drive the piston 50 by way of a gear train 42, such that rotation of a third rotor 58 causes the piston SO to be moved in relation to the third rotor 58.
Preferably, the user can feel the vibration of the motor 54 and the associated drive 25 mechanism 42 and/or hear them in operation. In this way an added degree of confidence in the fact of the operation of the injector 2 is provided to the user.
The functionality of a pen-type injector in accordance with the present invention will now be described, in particular with reference to Figures 1, 2 and 3.
The inj ector 2 is provided with an electronic control unit. The electronic control unit is coupled both to the drive mechanism and a user interface. The user interface includes the display panel 10 as well as the user operable buttons (and associated contacts). The electronic control unit is microprocessor based. Either volatile or non-volatile memory may be used for storage of 'dose history' and patient specific information.
The electronic control unit is preferably powered from the inj ector power source 3 ~.
The inj ector 2 preferably also includes a port for communication between the electronic 1o control unit and an external apparatus such as a personal computer.
The injector 2 also has a priming detection facility, (such as a tilt switch or accelerometer) to identify when the injector 2 is inverted. On detection of an inverted position (needle up) the injector 2 will automatically change state to be ready for priming.
Priming may be initiated by depression of the primer button 26 to cause a fixed small dispense action. The electronic control unit may cause a speaker to sound when the primer button 26 is depressed.
The primer button 26 is inactive at all other times. When the primer button 26 is active, 2o all other buttons in the control panel region are inactive, that is those buttons which are to be used to set or dispense a dose.
The electronic control unit may cause a speaker to sound when the arm button 16 is depressed for a sufficient period of time to provide audible feedbaclc for the user.
The function of the arm button 16 is to make the dispense button I8 active.
The arm button is preferably held down for a predetermined period of time before the injector 2 becomes armed. The armed status may additionally be shown on the display panel 10.
The functionality of the arm button is preferably linked to the cover detection switch 28 such that the arm button 16 will only function to arm the inj ector 2 when the cover 6 is not present.
Additionally, in a preferred embodiment, a cloclc within the electronic control unit will detect whether the dispense button 18 has been pressed within a specified time interval following arming of the injector 2. If the dispense button 18 has not been depressed within the specified time interval the electronic control unit will disarm the injector 2.
Alternatively, if the arm button is depressed a second time within a predetermined time period by the user, the injector will be disabled.
In an alternative embodiment, the dispense button I8 may function as both a prime button and the dose button. When the priming detector is actuated, by the injector 2 being oriented needle up, the dispense button 18 would change function to that of the prime button of the previous embodiment.
The buttons of the injector 2 are preferably tactile in nature to provide sensory feedback to the user.
The display panel 10 is typically an LCD display and will provide alphanumeric and 2o graphical information relating to the operation of the device.
Due to the use of an electromechanical drive, the dispense action is initiated by the user operating a switch. This means that the force required to operate the dispense button can be optimised for the comfort and ergonomic requirement of users.
In Figures 4, 5 and 6, there is shown a drive mechanism in the form of a single indexing gear arrangement. A push pull solenoid 270 is shown having an output shaft 272. The output shaft is coupled to a driving gear 278. The driving gear 278 is driven longitudinally within a gear housing 276. A shaft 280 of ~a lead screw is coupled to a 3o driven gear 274. The lead screw will be understood to comprise piston means for the advancement of bung 48 within a medicament cartridge 40 within the context of this description. The driven gear is located for movement longitudinally within the gear housing 276. Spring biassing means, typically a helical spring 282, are located between a rear face of the driven gear 274 and the gear housing 276 to urge the driven gear 274 toward the driving gear 278. Each of the driven gear 274 and the driving gear 278 are provided with angularly disposed teeth such that the teeth of the driven gear 274 may mate with the teeth of the driving gear 278.
The rotation of the driven gear 274 is aided by the presence of keyways (not shown) on the outer diameter of the driven gear 274 which engage with a set of splines (not shown) provided on an internal face of the housing 276. The splines prevent the driven gear 274 from meshing completely with the driving gear 278. As the driving gear advances on a push stroke of the solenoid 270, the driven gear 274 is pushed,.against the spring biassing means 282, along the splines until a point is reached where the driven gear 274 may disengage from the splines. At this point, the driven gear 274 rotates under the combined action of the pushing force of the spring biassing means and that of the solenoid until the teeth of the driven gear 274 and the driving gear 278 mesh (Figure 5).
On a return stroke, the driven gear 274 is returned, under the action of the spring biassing 2o means 282. However, due to the rotation the keyways now pick up the next spline location allowing the driven gear 274 to return to a longitudinal position corresponding to a start position, but angularly offset from the previous start position.
This drive mechanism has a number of advantages. In particular, it has no indeterminate position which might lead to jamming of the drive mechanism. Also, the drive mechanism latches at the end of each stroke, malting accidental dispense unlikely.
Claims (6)
1 A drive mechanism for an injection device in which piston means are selectively driven to expel medicament from within a medicament cartridge, the drive mechanism comprising drive means 270, first gear means 278 associated with the drive means, second gear means 274 being moveable between a first position in which only movement along its longitudinal axis is permitted and a second position in which the second gear means 274 is free to rotate about the longitudinal axis, the piston means 280 being associated with the second gear means 274, a housing 276 within which the first gear means 278 and the second gear means 274 are constrained for movement, and biassing means 282 located between the housing 276 and the second gear means 274 to bias the second gear means 274 to the first position.
2 A drive mechanism according to claim 1, characterised in that one of the second gear means 274 and the housing 276 is provided with a plurality of splines and the other of the second gear means 274 and the housing 276 is provided with keyways within which the splines are located when the second gear means 274 is in the first position.
3 A drive mechanism according to claim 1 or claim 2, characterised in that a first movement of the drive means 270 causes the first gear means 278 to advance from an initial position towards the second gear means 274 causing the second gear means 274 to be displaced from the first position to the second position and a second movement of the drive means 270 causes the first gear means 278 to return to the initial position thereby allowing the second drive means 274 to rotate and return to the first position under the action of the biassing means 282.
4 A drive mechanism according to any of claims 1 to 3, characterised in that the drive means 270 comprises a push pull solenoid.
A drive mechanism according to any of claims 1 to 4, characterised in that the biassing means 282 comprises a helical spring.
6 A drive mechanism according to any of claims 1 to 5, characterised in that the piston means comprises a lead screw.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0031466.6 | 2000-12-22 | ||
GBGB0031466.6A GB0031466D0 (en) | 2000-12-22 | 2000-12-22 | Improvements in and relating to an injection device |
PCT/GB2001/005704 WO2002051471A1 (en) | 2000-12-22 | 2001-12-21 | Drive mechanism for an injection device |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2430917A1 CA2430917A1 (en) | 2002-07-04 |
CA2430917C true CA2430917C (en) | 2009-02-17 |
Family
ID=9905751
Family Applications (13)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002430925A Abandoned CA2430925A1 (en) | 2000-12-22 | 2001-12-21 | Pen-type injector having an electronic control unit |
CA002430938A Expired - Fee Related CA2430938C (en) | 2000-12-22 | 2001-12-21 | Drive mechanism for an injection device |
CA002430917A Expired - Fee Related CA2430917C (en) | 2000-12-22 | 2001-12-21 | Drive mechanism for an injection device |
CA002430931A Expired - Fee Related CA2430931C (en) | 2000-12-22 | 2001-12-21 | Pen-type injector having an electronic control unit |
CA2430914A Expired - Fee Related CA2430914C (en) | 2000-12-22 | 2001-12-21 | Pen-type injector having an electronic control unit |
CA002430920A Expired - Fee Related CA2430920C (en) | 2000-12-22 | 2001-12-21 | Drive mechanism for an injection device |
CA002430922A Expired - Fee Related CA2430922C (en) | 2000-12-22 | 2001-12-21 | Pen-type injector having an electronic control unit |
CA002430788A Expired - Fee Related CA2430788C (en) | 2000-12-22 | 2001-12-21 | Pen-type injector having an electronic control unit |
CA002430942A Expired - Fee Related CA2430942C (en) | 2000-12-22 | 2001-12-21 | Pen-type injector having an electronic control unit |
CA002430940A Expired - Fee Related CA2430940C (en) | 2000-12-22 | 2001-12-21 | Injection device with replaceable cartridge |
CA002431135A Expired - Fee Related CA2431135C (en) | 2000-12-22 | 2001-12-21 | Dosing means for an injection device |
CA2430928A Expired - Fee Related CA2430928C (en) | 2000-12-22 | 2001-12-21 | Pen-type injector having an electronic control unit |
CA002430935A Expired - Fee Related CA2430935C (en) | 2000-12-22 | 2001-12-21 | Pen-type injector having holding mechanism for medicament cartridge |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002430925A Abandoned CA2430925A1 (en) | 2000-12-22 | 2001-12-21 | Pen-type injector having an electronic control unit |
CA002430938A Expired - Fee Related CA2430938C (en) | 2000-12-22 | 2001-12-21 | Drive mechanism for an injection device |
Family Applications After (10)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002430931A Expired - Fee Related CA2430931C (en) | 2000-12-22 | 2001-12-21 | Pen-type injector having an electronic control unit |
CA2430914A Expired - Fee Related CA2430914C (en) | 2000-12-22 | 2001-12-21 | Pen-type injector having an electronic control unit |
CA002430920A Expired - Fee Related CA2430920C (en) | 2000-12-22 | 2001-12-21 | Drive mechanism for an injection device |
CA002430922A Expired - Fee Related CA2430922C (en) | 2000-12-22 | 2001-12-21 | Pen-type injector having an electronic control unit |
CA002430788A Expired - Fee Related CA2430788C (en) | 2000-12-22 | 2001-12-21 | Pen-type injector having an electronic control unit |
CA002430942A Expired - Fee Related CA2430942C (en) | 2000-12-22 | 2001-12-21 | Pen-type injector having an electronic control unit |
CA002430940A Expired - Fee Related CA2430940C (en) | 2000-12-22 | 2001-12-21 | Injection device with replaceable cartridge |
CA002431135A Expired - Fee Related CA2431135C (en) | 2000-12-22 | 2001-12-21 | Dosing means for an injection device |
CA2430928A Expired - Fee Related CA2430928C (en) | 2000-12-22 | 2001-12-21 | Pen-type injector having an electronic control unit |
CA002430935A Expired - Fee Related CA2430935C (en) | 2000-12-22 | 2001-12-21 | Pen-type injector having holding mechanism for medicament cartridge |
Country Status (19)
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US (13) | US8128603B2 (en) |
EP (13) | EP1349593B2 (en) |
JP (16) | JP4150589B2 (en) |
KR (13) | KR100826218B1 (en) |
CN (13) | CN1292807C (en) |
AT (12) | ATE295749T1 (en) |
AU (12) | AU2002217288B2 (en) |
BR (13) | BR0116294A (en) |
CA (13) | CA2430925A1 (en) |
CY (3) | CY1106128T1 (en) |
DE (12) | DE60112472T3 (en) |
DK (12) | DK1349594T3 (en) |
ES (12) | ES2283375T3 (en) |
GB (1) | GB0031466D0 (en) |
HK (12) | HK1059585A1 (en) |
IL (22) | IL156245A0 (en) |
MX (13) | MXPA03005593A (en) |
PT (12) | PT1353713E (en) |
WO (13) | WO2002051475A1 (en) |
Families Citing this family (315)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7885697B2 (en) * | 2004-07-13 | 2011-02-08 | Dexcom, Inc. | Transcutaneous analyte sensor |
US6175752B1 (en) | 1998-04-30 | 2001-01-16 | Therasense, Inc. | Analyte monitoring device and methods of use |
US8974386B2 (en) | 1998-04-30 | 2015-03-10 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
US6949816B2 (en) | 2003-04-21 | 2005-09-27 | Motorola, Inc. | Semiconductor component having first surface area for electrically coupling to a semiconductor chip and second surface area for electrically coupling to a substrate, and method of manufacturing same |
US8688188B2 (en) | 1998-04-30 | 2014-04-01 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
US8480580B2 (en) | 1998-04-30 | 2013-07-09 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
US8346337B2 (en) | 1998-04-30 | 2013-01-01 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
US8465425B2 (en) | 1998-04-30 | 2013-06-18 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
US9066695B2 (en) | 1998-04-30 | 2015-06-30 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
US20010041869A1 (en) * | 2000-03-23 | 2001-11-15 | Causey James D. | Control tabs for infusion devices and methods of using the same |
IL156245A0 (en) * | 2000-12-22 | 2004-01-04 | Dca Design Int Ltd | Drive mechanism for an injection device |
US6560471B1 (en) | 2001-01-02 | 2003-05-06 | Therasense, Inc. | Analyte monitoring device and methods of use |
DE60323729D1 (en) | 2002-02-11 | 2008-11-06 | Antares Pharma Inc | INTRADERMAL INJECTION DEVICE |
US8010174B2 (en) | 2003-08-22 | 2011-08-30 | Dexcom, Inc. | Systems and methods for replacing signal artifacts in a glucose sensor data stream |
US8260393B2 (en) | 2003-07-25 | 2012-09-04 | Dexcom, Inc. | Systems and methods for replacing signal data artifacts in a glucose sensor data stream |
US9247901B2 (en) | 2003-08-22 | 2016-02-02 | Dexcom, Inc. | Systems and methods for replacing signal artifacts in a glucose sensor data stream |
US9282925B2 (en) | 2002-02-12 | 2016-03-15 | Dexcom, Inc. | Systems and methods for replacing signal artifacts in a glucose sensor data stream |
EP1391794A1 (en) * | 2002-07-23 | 2004-02-25 | Novo Nordisk A/S | Device with time indicating means |
JP4198435B2 (en) | 2002-10-15 | 2008-12-17 | 富士電機エフテック株式会社 | Electric syringe for dental anesthesia |
FR2846308B1 (en) * | 2002-10-28 | 2006-02-10 | Valois Sas | FLUID PRODUCT DISPENSING DEVICE WITH DOSE INDICATOR |
FR2846453B1 (en) * | 2002-10-28 | 2005-01-28 | Valois Sas | ELECTRONIC DISPLAY DEVICE AND FLUID PRODUCT DELIVERY DEVICE HAVING SUCH A DISPLAY DEVICE |
AU2002953483A0 (en) * | 2002-12-20 | 2003-01-09 | Acrux Dds Pty. Ltd. | Usage indicator |
US6814265B2 (en) * | 2003-03-06 | 2004-11-09 | Alcon, Inc. | Device for dispensing fluid medicine |
GB0311461D0 (en) | 2003-05-19 | 2003-06-25 | Glaxo Group Ltd | Display system |
CA2529378C (en) * | 2003-06-20 | 2014-04-15 | F.Hoffmann-La Roche Ag | Method and reagent for producing narrow, homogenous reagent strips |
US8423113B2 (en) | 2003-07-25 | 2013-04-16 | Dexcom, Inc. | Systems and methods for processing sensor data |
US20070208245A1 (en) * | 2003-08-01 | 2007-09-06 | Brauker James H | Transcutaneous analyte sensor |
US7591801B2 (en) * | 2004-02-26 | 2009-09-22 | Dexcom, Inc. | Integrated delivery device for continuous glucose sensor |
US7925321B2 (en) | 2003-08-01 | 2011-04-12 | Dexcom, Inc. | System and methods for processing analyte sensor data |
US8160669B2 (en) * | 2003-08-01 | 2012-04-17 | Dexcom, Inc. | Transcutaneous analyte sensor |
US8275437B2 (en) | 2003-08-01 | 2012-09-25 | Dexcom, Inc. | Transcutaneous analyte sensor |
US9135402B2 (en) | 2007-12-17 | 2015-09-15 | Dexcom, Inc. | Systems and methods for processing sensor data |
US20190357827A1 (en) | 2003-08-01 | 2019-11-28 | Dexcom, Inc. | Analyte sensor |
US8845536B2 (en) | 2003-08-01 | 2014-09-30 | Dexcom, Inc. | Transcutaneous analyte sensor |
US20100168657A1 (en) | 2003-08-01 | 2010-07-01 | Dexcom, Inc. | System and methods for processing analyte sensor data |
US8369919B2 (en) | 2003-08-01 | 2013-02-05 | Dexcom, Inc. | Systems and methods for processing sensor data |
US8761856B2 (en) | 2003-08-01 | 2014-06-24 | Dexcom, Inc. | System and methods for processing analyte sensor data |
US8886273B2 (en) | 2003-08-01 | 2014-11-11 | Dexcom, Inc. | Analyte sensor |
US6931327B2 (en) | 2003-08-01 | 2005-08-16 | Dexcom, Inc. | System and methods for processing analyte sensor data |
US7774145B2 (en) | 2003-08-01 | 2010-08-10 | Dexcom, Inc. | Transcutaneous analyte sensor |
US20140121989A1 (en) | 2003-08-22 | 2014-05-01 | Dexcom, Inc. | Systems and methods for processing analyte sensor data |
US7920906B2 (en) | 2005-03-10 | 2011-04-05 | Dexcom, Inc. | System and methods for processing analyte sensor data for sensor calibration |
JP4704351B2 (en) * | 2003-11-06 | 2011-06-15 | ライフスキャン・インコーポレイテッド | Drug introduction pen with event notification means |
US9247900B2 (en) | 2004-07-13 | 2016-02-02 | Dexcom, Inc. | Analyte sensor |
WO2005051170A2 (en) | 2003-11-19 | 2005-06-09 | Dexcom, Inc. | Integrated receiver for continuous analyte sensor |
EP2239566B1 (en) | 2003-12-05 | 2014-04-23 | DexCom, Inc. | Calibration techniques for a continuous analyte sensor |
US8287453B2 (en) | 2003-12-05 | 2012-10-16 | Dexcom, Inc. | Analyte sensor |
US8423114B2 (en) | 2006-10-04 | 2013-04-16 | Dexcom, Inc. | Dual electrode system for a continuous analyte sensor |
US8774886B2 (en) | 2006-10-04 | 2014-07-08 | Dexcom, Inc. | Analyte sensor |
US8364231B2 (en) | 2006-10-04 | 2013-01-29 | Dexcom, Inc. | Analyte sensor |
US11633133B2 (en) | 2003-12-05 | 2023-04-25 | Dexcom, Inc. | Dual electrode system for a continuous analyte sensor |
WO2005057175A2 (en) * | 2003-12-09 | 2005-06-23 | Dexcom, Inc. | Signal processing for continuous analyte sensor |
EP1543854A1 (en) * | 2003-12-16 | 2005-06-22 | Novo Nordisk A/S | Vibrating injection needle and method for detecting the presence of medicament therein |
SI1715904T1 (en) * | 2004-02-18 | 2016-01-29 | Ares Trading S.A. | Hand-held electronically controlled injection device for injecting liquid medications |
US8808228B2 (en) | 2004-02-26 | 2014-08-19 | Dexcom, Inc. | Integrated medicament delivery device for use with continuous analyte sensor |
WO2005084732A1 (en) * | 2004-03-03 | 2005-09-15 | Nemoto Kyorindo Co., Ltd. | Medical solution injection system |
JP4549079B2 (en) | 2004-03-05 | 2010-09-22 | パナソニック株式会社 | Medical dosing device |
DE102004013415B4 (en) * | 2004-03-18 | 2011-12-08 | Disetronic Licensing Ag | Rotatable display of a medical, pharmaceutical or cosmetic device |
US7927307B2 (en) * | 2004-06-09 | 2011-04-19 | Mark Anderson and Associates, Inc. | Hypodermic injection system |
WO2005124366A1 (en) * | 2004-06-14 | 2005-12-29 | Parker-Hannifin Corporation | Robotic handling system and method with independently operable detachable tools |
US7857760B2 (en) | 2004-07-13 | 2010-12-28 | Dexcom, Inc. | Analyte sensor |
US20060016700A1 (en) | 2004-07-13 | 2006-01-26 | Dexcom, Inc. | Transcutaneous analyte sensor |
US7783333B2 (en) | 2004-07-13 | 2010-08-24 | Dexcom, Inc. | Transcutaneous medical device with variable stiffness |
US8452368B2 (en) | 2004-07-13 | 2013-05-28 | Dexcom, Inc. | Transcutaneous analyte sensor |
US8565848B2 (en) | 2004-07-13 | 2013-10-22 | Dexcom, Inc. | Transcutaneous analyte sensor |
US7255684B2 (en) * | 2004-08-09 | 2007-08-14 | Boris Zubry | Medical injection system |
KR100620517B1 (en) * | 2004-08-27 | 2006-09-12 | (주)옥토메티칼어플라이언스 | Insulin Auto Feeder |
EP1640029A1 (en) * | 2004-09-24 | 2006-03-29 | Novo Nordisk A/S | Injection device with cap |
WO2006045524A1 (en) * | 2004-10-21 | 2006-05-04 | Novo Nordisk A/S | An injection device with means for signalling the time since the last injection |
US7648483B2 (en) | 2004-11-22 | 2010-01-19 | Intelliject, Inc. | Devices, systems and methods for medicament delivery |
US7947017B2 (en) | 2004-11-22 | 2011-05-24 | Intelliject, Inc. | Devices, systems and methods for medicament delivery |
US11590286B2 (en) | 2004-11-22 | 2023-02-28 | Kaleo, Inc. | Devices, systems and methods for medicament delivery |
US7648482B2 (en) | 2004-11-22 | 2010-01-19 | Intelliject, Inc. | Devices, systems, and methods for medicament delivery |
CA2891057C (en) | 2004-11-22 | 2018-11-13 | Kaleo, Inc. | Medicament delivery apparatus and movable indicator |
US10737028B2 (en) | 2004-11-22 | 2020-08-11 | Kaleo, Inc. | Devices, systems and methods for medicament delivery |
JP5216328B2 (en) | 2005-01-24 | 2013-06-19 | アンタレス ファーマ インコーポレイテッド | Pre-filled needle assist syringe jet injector |
US8057756B2 (en) * | 2005-01-28 | 2011-11-15 | Parker-Hannifin Corporation | Sampling probe, gripper and interface for laboratory sample management systems |
US8361026B2 (en) * | 2005-02-01 | 2013-01-29 | Intelliject, Inc. | Apparatus and methods for self-administration of vaccines and other medicaments |
US8206360B2 (en) | 2005-02-01 | 2012-06-26 | Intelliject, Inc. | Devices, systems and methods for medicament delivery |
US7731686B2 (en) * | 2005-02-01 | 2010-06-08 | Intelliject, Inc. | Devices, systems and methods for medicament delivery |
US8231573B2 (en) | 2005-02-01 | 2012-07-31 | Intelliject, Inc. | Medicament delivery device having an electronic circuit system |
JP4948422B2 (en) | 2005-02-01 | 2012-06-06 | インテリジェクト,インコーポレイテッド | Drug delivery apparatus, system and method |
US9022980B2 (en) | 2005-02-01 | 2015-05-05 | Kaleo, Inc. | Medical injector simulation device |
US7833189B2 (en) | 2005-02-11 | 2010-11-16 | Massachusetts Institute Of Technology | Controlled needle-free transport |
EP1690559A1 (en) | 2005-02-14 | 2006-08-16 | Ares Trading S.A. | Medication delivery device |
EP1690560A1 (en) * | 2005-02-14 | 2006-08-16 | Ares Trading S.A. | Medication delivery device |
US7993300B2 (en) * | 2005-02-21 | 2011-08-09 | Novo Nordisk As | Method for ensuring constant speed of a motor in an injection device |
DE202005010389U1 (en) * | 2005-07-01 | 2005-09-08 | Tecpharma Licensing Ag | Injection unit capable of accommodating an ampule incorporates a fixed magnet and a counter-magnet on the movable piston rod of the unit |
US20070060887A1 (en) * | 2005-08-22 | 2007-03-15 | Marsh David A | Ophthalmic injector |
EP1759727A1 (en) * | 2005-09-02 | 2007-03-07 | F.Hoffmann-La Roche Ag | Infusion device having a control unit |
EP1933901B1 (en) * | 2005-09-26 | 2014-12-31 | Asante Solutions, Inc. | Portable infusion pump having a flexible pushrod with hinged portions |
US20080314412A1 (en) * | 2005-12-05 | 2008-12-25 | Grippo Paul M | Self-Cleaning Injection Port for Analytical Applications |
US20090032065A1 (en) * | 2005-12-08 | 2009-02-05 | Bantz Daniel L | Syringe wash station for analytical applications |
GB2433032A (en) † | 2005-12-08 | 2007-06-13 | Owen Mumford Ltd | Syringe with dose adjustment means |
DE102005059508A1 (en) * | 2005-12-13 | 2007-06-14 | Tecpharma Licensing Ag | Electricity generating pen |
US8192698B2 (en) * | 2006-01-27 | 2012-06-05 | Parker-Hannifin Corporation | Sampling probe, gripper and interface for laboratory sample management systems |
US8147460B2 (en) * | 2006-01-31 | 2012-04-03 | Roche Diagnostics International Ag | Administering device with a multi-component injection-moulded housing |
US7931620B2 (en) * | 2006-02-01 | 2011-04-26 | Roche Diagnostics International Ag | Self-sealing connection for housing shells of an administering device |
KR100737441B1 (en) * | 2006-02-09 | 2007-07-09 | 단국대학교 산학협력단 | Electro-motion syringe |
US7959609B2 (en) * | 2006-02-14 | 2011-06-14 | Battelle Memorial Institute | Accurate metering system |
US20090005735A1 (en) * | 2006-03-03 | 2009-01-01 | Shl Group Ab | Medical Device with Orientation Sensitive Priming Mechanism |
EP1991110B1 (en) | 2006-03-09 | 2018-11-07 | DexCom, Inc. | Systems and methods for processing analyte sensor data |
WO2007107559A1 (en) * | 2006-03-20 | 2007-09-27 | Novo Nordisk A/S | Flat assembly for medication delivery device |
EP1998751B1 (en) * | 2006-03-29 | 2020-08-19 | Kaleo, Inc. | System for medicament delivery |
WO2007131025A1 (en) | 2006-05-03 | 2007-11-15 | Antares Pharma, Inc. | Injector with adjustable dosing |
US8251947B2 (en) | 2006-05-03 | 2012-08-28 | Antares Pharma, Inc. | Two-stage reconstituting injector |
US7811252B2 (en) * | 2006-05-17 | 2010-10-12 | Alcon Research, Ltd. | Dosage control device |
US7871399B2 (en) | 2006-05-17 | 2011-01-18 | Alcon Research, Ltd. | Disposable ophthalmic injection device |
US7887521B2 (en) * | 2006-05-17 | 2011-02-15 | Alcon Research, Ltd. | Ophthalmic injection system |
WO2007143225A2 (en) | 2006-06-07 | 2007-12-13 | Abbott Diabetes Care, Inc. | Analyte monitoring system and method |
NZ572765A (en) * | 2006-06-30 | 2012-08-31 | Abbott Biotech Ltd | Automatic injection device with rod driving syringe longitudinally split with radially compressible pair of wings along its length |
DE102006047613A1 (en) * | 2006-10-07 | 2008-04-10 | Sanofi-Aventis Deutschland Gmbh | Peristaltic micropump with exchangeable pump head |
EP1911479A1 (en) * | 2006-10-09 | 2008-04-16 | F.Hoffmann-La Roche Ag | Drug delivery device with magnetic connection between piston and piston rod |
DE102006048180A1 (en) * | 2006-10-10 | 2008-04-17 | Tecpharma Licensing Ag | Injection device with a trigger lock with not inserted product container |
AU2007347736A1 (en) * | 2006-10-16 | 2008-09-04 | Alcon Research, Ltd. | Universal rechargeable limited reuse assembly for ophthalmic hand piece |
AU2007348611A1 (en) * | 2006-10-16 | 2008-09-12 | Alcon Research, Ltd. | Method of operating ophthalmic hand piece with disposable end |
US20080281292A1 (en) * | 2006-10-16 | 2008-11-13 | Hickingbotham Dyson W | Retractable Injection Port |
AU2007347669A1 (en) * | 2006-10-16 | 2008-09-04 | Alcon Research, Ltd. | Ceramic chamber with integrated temperature control device for ophthalmic medical device |
US9022970B2 (en) * | 2006-10-16 | 2015-05-05 | Alcon Research, Ltd. | Ophthalmic injection device including dosage control device |
WO2008083875A1 (en) * | 2007-01-09 | 2008-07-17 | Shl Medical Ab | Information device |
WO2008091838A2 (en) | 2007-01-22 | 2008-07-31 | Intelliject, Inc. | Medical injector with compliance tracking and monitoring |
US7910392B2 (en) * | 2007-04-02 | 2011-03-22 | Solaria Corporation | Method and system for assembling a solar cell package |
US7817498B1 (en) * | 2007-05-11 | 2010-10-19 | Michael R. Schramm | Medical apparatus having elapsed time indicated and method of use |
CA2688184A1 (en) * | 2007-06-08 | 2008-12-18 | Dexcom, Inc. | Integrated medicament delivery device for use with continuous analyte sensor |
US9205193B2 (en) * | 2007-06-12 | 2015-12-08 | Peter V. Boesen | Self-contained medication injection system and method |
US9452258B2 (en) | 2007-10-09 | 2016-09-27 | Dexcom, Inc. | Integrated insulin delivery system with continuous glucose sensor |
US8417312B2 (en) | 2007-10-25 | 2013-04-09 | Dexcom, Inc. | Systems and methods for processing sensor data |
EP2219710B2 (en) | 2007-11-12 | 2020-08-05 | Medicom Innovation Partner a/s | Auto injector with automatic needle retraction |
US9839395B2 (en) | 2007-12-17 | 2017-12-12 | Dexcom, Inc. | Systems and methods for processing sensor data |
US8579866B2 (en) | 2008-01-11 | 2013-11-12 | Ucb Pharma, S.A. | Systems and methods for administering medication |
CA2715624A1 (en) * | 2008-02-20 | 2009-08-27 | Dexcom, Inc. | Continuous medicament sensor system for in vivo use |
CA2715628A1 (en) | 2008-02-21 | 2009-08-27 | Dexcom, Inc. | Systems and methods for processing, transmitting and displaying sensor data |
WO2009114542A1 (en) | 2008-03-10 | 2009-09-17 | Antares Pharma, Inc. | Injector safety device |
US8396528B2 (en) | 2008-03-25 | 2013-03-12 | Dexcom, Inc. | Analyte sensor |
JP5313236B2 (en) | 2008-04-10 | 2013-10-09 | パナソニック株式会社 | Drug administration device |
USD994111S1 (en) | 2008-05-12 | 2023-08-01 | Kaleo, Inc. | Medicament delivery device cover |
JP5653345B2 (en) * | 2008-05-12 | 2015-01-14 | カレオ,インコーポレイテッド | Drug delivery device with electronic circuit system |
US8021344B2 (en) | 2008-07-28 | 2011-09-20 | Intelliject, Inc. | Medicament delivery device configured to produce an audible output |
US7862534B2 (en) * | 2008-06-11 | 2011-01-04 | Bracco Diagnostics Inc. | Infusion circuit subassemblies |
US9597053B2 (en) * | 2008-06-11 | 2017-03-21 | Bracco Diagnostics Inc. | Infusion systems including computer-facilitated maintenance and/or operation and methods of use |
EP2300076B1 (en) * | 2008-06-11 | 2020-05-27 | Bracco Diagnostics Inc. | Shielding assemblies for infusion systems |
US8317674B2 (en) | 2008-06-11 | 2012-11-27 | Bracco Diagnostics Inc. | Shielding assemblies for infusion systems |
US8708352B2 (en) | 2008-06-11 | 2014-04-29 | Bracco Diagnostics Inc. | Cabinet structure configurations for infusion systems |
EP2303362B1 (en) * | 2008-07-18 | 2019-06-05 | Becton, Dickinson and Company | Dual chamber and gear pump assembly for a high pressure delivery system |
AU2009279719B2 (en) | 2008-08-05 | 2015-07-23 | Antares Pharma, Inc. | Multiple dosage injector |
JP5603335B2 (en) | 2008-08-29 | 2014-10-08 | ノボ・ノルデイスク・エー/エス | Medical syringe with time delay indicator |
WO2010033770A2 (en) | 2008-09-18 | 2010-03-25 | Becton, Dickinson And Company | Medical injector with ratcheting plunger |
US9801575B2 (en) | 2011-04-15 | 2017-10-31 | Dexcom, Inc. | Advanced analyte sensor calibration and error detection |
US8840591B2 (en) | 2008-12-12 | 2014-09-23 | Sanofi-Aventis Deutschland Gmbh | Drive mechanism for a medication delivery device and medication delivery device |
EP2196233A1 (en) | 2008-12-12 | 2010-06-16 | Sanofi-Aventis Deutschland GmbH | Resettable drive mechanism for a medication delivery device and medication delivery device |
EP2359881B1 (en) | 2008-12-16 | 2022-07-20 | PHC Holdings Corporation | Medication administering device |
DK2206529T4 (en) † | 2008-12-18 | 2020-08-10 | Sanofi Aventis Deutschland | Drug delivery device and method of making a drug delivery device |
WO2010073452A1 (en) * | 2008-12-22 | 2010-07-01 | パナソニック株式会社 | Medicament dispensing device |
EP2208503A1 (en) | 2009-01-20 | 2010-07-21 | Sanofi-Aventis Deutschland GmbH | Drive assembly and medication delivery device |
WO2010089310A1 (en) * | 2009-02-05 | 2010-08-12 | Sanofi-Aventis Deutschland Gmbh | Medicament delivery devices |
US8807169B2 (en) | 2009-02-12 | 2014-08-19 | Picolife Technologies, Llc | Flow control system for a micropump |
CN102413856B (en) * | 2009-02-27 | 2017-02-08 | 生命扫描有限公司 | Drug delivery system |
DE202009003009U1 (en) * | 2009-03-03 | 2009-06-25 | Dieter Hölzle Technik-Projekte GmbH | Injection device with injection volume adjustment |
JP5451741B2 (en) * | 2009-03-04 | 2014-03-26 | パナソニック株式会社 | Drug injection device |
AU2010226442A1 (en) | 2009-03-20 | 2011-10-13 | Antares Pharma, Inc. | Hazardous agent injection system |
US9446194B2 (en) | 2009-03-27 | 2016-09-20 | Dexcom, Inc. | Methods and systems for promoting glucose management |
US9227009B2 (en) | 2009-04-30 | 2016-01-05 | Sanofi-Aventis Deutschland Gmbh | Pen-type injector with ergonomic button arrangement |
WO2010125153A1 (en) * | 2009-04-30 | 2010-11-04 | Sanofi-Aventis Deutschland Gmbh | Pen-type injector with ergonomic button arrangement |
US20100286612A1 (en) * | 2009-05-06 | 2010-11-11 | William Cirillo | Medication injection supervisor device |
US8632511B2 (en) * | 2009-05-06 | 2014-01-21 | Alcon Research, Ltd. | Multiple thermal sensors in a multiple processor environment for temperature control in a drug delivery device |
EP2432525A1 (en) * | 2009-05-20 | 2012-03-28 | Sanofi-Aventis Deutschland GmbH | Drug delivery device |
KR101036543B1 (en) * | 2009-05-28 | 2011-05-24 | 린나이코리아 주식회사 | Over floe cover of dish washer |
US9623187B2 (en) | 2009-06-01 | 2017-04-18 | Sanofi-Aventis Deutschland Gmbh | Resettable drug delivery device |
CN102458514B (en) * | 2009-06-03 | 2014-09-03 | 诺沃—诺迪斯克有限公司 | Electronically monitored injection device |
ES2558768T3 (en) * | 2009-06-24 | 2016-02-08 | Tecpharma Licensing Ag | Administration device with priming function |
CN101987220B (en) * | 2009-07-30 | 2013-11-13 | 德昌电机(深圳)有限公司 | Needle driving assembly for medical instrument |
US8758271B2 (en) | 2009-09-01 | 2014-06-24 | Massachusetts Institute Of Technology | Nonlinear system identification techniques and devices for discovering dynamic and static tissue properties |
US8642088B2 (en) | 2009-09-04 | 2014-02-04 | Wisconsin Alumni Research Foundation | Tannin-chitosan composites |
JP5726194B2 (en) * | 2009-09-18 | 2015-05-27 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | Latching and control device for integration in medical devices |
JP4873061B2 (en) * | 2009-10-09 | 2012-02-08 | パナソニック株式会社 | Medical dosing device |
DE102009053154A1 (en) | 2009-11-06 | 2011-05-12 | Tecpharma Licensing Ag | Administration device e.g. autoinjector for administrating insulin, has actuating element releasing blocking element, and driven element movable around priming stroke to discharge condition by storage unit when block element is released |
EP2335755A1 (en) | 2009-12-17 | 2011-06-22 | Sanofi-Aventis Deutschland GmbH | Device and method for delivery of two or more drug agents |
US8177747B2 (en) * | 2009-12-22 | 2012-05-15 | Alcon Research, Ltd. | Method and apparatus for drug delivery |
JP5598903B2 (en) | 2010-01-29 | 2014-10-01 | 富士電機エフテック株式会社 | Electric syringe for chemicals |
CN102812469A (en) * | 2010-04-09 | 2012-12-05 | 诺沃—诺迪斯克有限公司 | Reminder programming device and method |
US8740838B2 (en) * | 2010-10-07 | 2014-06-03 | Massachusetts Institute Of Technology | Injection methods using a servo-controlled needle-free injector |
EP2667918B1 (en) | 2011-01-24 | 2017-03-01 | AbbVie Biotechnology Ltd | Automatic injection devices having overmolded gripping surfaces |
US9084849B2 (en) | 2011-01-26 | 2015-07-21 | Kaleo, Inc. | Medicament delivery devices for administration of a medicament within a prefilled syringe |
US8939943B2 (en) | 2011-01-26 | 2015-01-27 | Kaleo, Inc. | Medicament delivery device for administration of opioid antagonists including formulations for naloxone |
US8627816B2 (en) | 2011-02-28 | 2014-01-14 | Intelliject, Inc. | Medicament delivery device for administration of opioid antagonists including formulations for naloxone |
US20120239020A1 (en) * | 2011-03-15 | 2012-09-20 | Tyco Healthcare Group Lp | Geo-Location Addition to Electrosurgical Generator |
CN105498049B (en) * | 2011-03-17 | 2018-09-21 | 贝克顿·迪金森公司 | Medical injector with ratchet-type plunger |
EP2689359B1 (en) * | 2011-03-24 | 2020-11-25 | Sanofi-Aventis Deutschland GmbH | Device and method for detecting an actuation action performable with a medical device |
WO2012153295A2 (en) * | 2011-05-10 | 2012-11-15 | Insuline Medical Ltd | Device, system and method for facilitating syringe based drug delivery and management thereof |
JP3181663U (en) | 2011-05-12 | 2013-02-21 | メドラッド、インク. | Syringes for use in fluid delivery systems |
US9492618B2 (en) * | 2011-05-25 | 2016-11-15 | Sanofi-Aventis Deutschland Gmbh | Medicament injection device and priming operation |
CN103688332A (en) * | 2011-05-25 | 2014-03-26 | 赛诺菲-安万特德国有限公司 | Handheld medicament delivery device with dose button |
DK2714135T3 (en) | 2011-05-25 | 2023-02-06 | Sanofi Aventis Deutschland | MEDICATION ADMINISTRATION DEVICE AND METHOD OF CONTROLLING THE DEVICE |
US9878092B2 (en) | 2011-06-02 | 2018-01-30 | Ucb Biopharma Sprl | Auto-injector |
US8496619B2 (en) | 2011-07-15 | 2013-07-30 | Antares Pharma, Inc. | Injection device with cammed ram assembly |
US9220660B2 (en) | 2011-07-15 | 2015-12-29 | Antares Pharma, Inc. | Liquid-transfer adapter beveled spike |
WO2013010893A1 (en) | 2011-07-15 | 2013-01-24 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device with electro-mechanic drive mechanism |
EP2756858B1 (en) | 2011-09-12 | 2017-06-14 | Panasonic Healthcare Co., Ltd. | Drug injection device |
US9192722B2 (en) * | 2011-09-12 | 2015-11-24 | Panasonic Healthcare Holdings Co., Ltd. | Pharmaceutical injection device |
EP2574357B1 (en) * | 2011-09-28 | 2013-11-13 | Q-Med AB | Electronic injector |
JP5974016B2 (en) | 2011-11-10 | 2016-08-23 | パナソニックヘルスケアホールディングス株式会社 | Drug injection device |
US8790307B2 (en) | 2011-12-01 | 2014-07-29 | Picolife Technologies, Llc | Drug delivery device and methods therefor |
US8771229B2 (en) | 2011-12-01 | 2014-07-08 | Picolife Technologies, Llc | Cartridge system for delivery of medicament |
US8834449B2 (en) | 2012-01-23 | 2014-09-16 | Ikomed Technologies, Inc. | Mixing syringe |
US9751056B2 (en) | 2012-01-23 | 2017-09-05 | Merit Medical Systems, Inc. | Mixing syringe |
JP2013150672A (en) * | 2012-01-24 | 2013-08-08 | Terumo Corp | Sterile joining device |
JP6305939B2 (en) * | 2012-02-13 | 2018-04-04 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | Auxiliary device attached to injection device |
DK2822618T3 (en) | 2012-03-06 | 2024-01-22 | Antares Pharma Inc | Pre-filled needle with breaking force function |
US10130759B2 (en) | 2012-03-09 | 2018-11-20 | Picolife Technologies, Llc | Multi-ported drug delivery device having multi-reservoir cartridge system |
US10283014B2 (en) * | 2012-04-04 | 2019-05-07 | Jbcb Holdings, Llc | Smart packaging and display system |
US10748449B2 (en) | 2012-04-04 | 2020-08-18 | Noble International, Inc. | Medicament delivery training device |
EP2833944A4 (en) | 2012-04-06 | 2016-05-25 | Antares Pharma Inc | Needle assisted jet injection administration of testosterone compositions |
US9883834B2 (en) | 2012-04-16 | 2018-02-06 | Farid Amirouche | Medication delivery device with multi-reservoir cartridge system and related methods of use |
WO2013169800A1 (en) | 2012-05-07 | 2013-11-14 | Antares Pharma, Inc. | Injection device with cammed ram assembly |
US9522235B2 (en) | 2012-05-22 | 2016-12-20 | Kaleo, Inc. | Devices and methods for delivering medicaments from a multi-chamber container |
US8784372B1 (en) | 2012-06-12 | 2014-07-22 | Johnathan D. Hoggatt | First aid pen having separate compartments |
US10245420B2 (en) | 2012-06-26 | 2019-04-02 | PicoLife Technologies | Medicament distribution systems and related methods of use |
EP2879738B1 (en) | 2012-07-30 | 2019-09-11 | UCB Biopharma SPRL | Auto-injector |
EP2879735B1 (en) | 2012-07-30 | 2019-11-20 | UCB Biopharma SPRL | Auto-injector |
EP2879737B1 (en) | 2012-07-30 | 2018-09-12 | UCB Biopharma SPRL | Auto-injector |
USD726901S1 (en) | 2012-07-30 | 2015-04-14 | Ucb Pharma S.A. | Drive device for administering medication |
US9757521B2 (en) | 2012-07-30 | 2017-09-12 | Ucb Biopharma Sprl | Auto-injector |
DK2885031T3 (en) | 2012-08-20 | 2018-01-08 | Sanofi Aventis Deutschland | PHARMACEUTICAL DISPENSER DEVICE AND PROCEDURE FOR ELECTRIC DETECTION OF CONTACT BETWEEN Piston Rod and Cartridge Plug |
CN104602736B (en) | 2012-09-05 | 2018-04-20 | E3D农业合作协会有限公司 | Electronics automatic injection device |
CN103656782B (en) * | 2012-09-21 | 2016-04-13 | 上海微创生命科技有限公司 | For monitoring the method and apparatus of the infusion of novopen |
EP2716317A1 (en) * | 2012-10-04 | 2014-04-09 | Sanofi-Aventis Deutschland GmbH | Medicament delivery device with trigger button |
GB2508588A (en) * | 2012-11-30 | 2014-06-11 | Owen Mumford Ltd | Medical delivery device comprising mechanical-electrical transducer |
EP3178505B1 (en) | 2012-12-13 | 2018-05-02 | Panasonic Healthcare Holdings Co., Ltd. | Medicament injection device |
CN103007391B (en) * | 2012-12-19 | 2014-12-03 | 四川大学 | Predictive adaptive control system for liquid medicament push-injecting |
CA2896708A1 (en) | 2012-12-27 | 2014-07-03 | Kaleo, Inc. | Devices, systems and methods for locating and interacting with medicament delivery systems |
DK2945668T3 (en) | 2013-01-15 | 2018-09-03 | Sanofi Aventis Deutschland | ASSEMBLY ASSEMBLY FOR A MEDICAL INJECTION DEVICE FOR GENERATION OF USE REPORTS ON THE USE OF THE DIGITAL IMAGE INJECTION DEVICE |
JP6348514B2 (en) * | 2013-01-29 | 2018-06-27 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | Electronically controlled drug delivery device with touch screen |
DK2950855T3 (en) * | 2013-01-29 | 2017-02-20 | Sanofi Aventis Deutschland | Drug delivery device |
EP2953667B1 (en) | 2013-02-11 | 2019-10-23 | Antares Pharma, Inc. | Needle assisted jet injection device having reduced trigger force |
US9707354B2 (en) | 2013-03-11 | 2017-07-18 | Antares Pharma, Inc. | Multiple dosage injector with rack and pinion dosage system |
WO2014165136A1 (en) | 2013-03-12 | 2014-10-09 | Antares Pharma, Inc. | Constant volume prefilled syringes and kits thereof |
US20140276413A1 (en) * | 2013-03-15 | 2014-09-18 | Jeff Baker | Medicament delivery and simulation system with a removable disposable container for medicament and a rotatable actuation component |
PL2981312T3 (en) * | 2013-04-05 | 2018-06-29 | Novo Nordisk A/S | Logging device adapted to combine doses |
JP6756806B2 (en) * | 2013-04-05 | 2020-09-16 | ノボ・ノルデイスク・エー/エス | Logging device that combines multiple doses |
CN103285490A (en) * | 2013-05-29 | 2013-09-11 | 毕良佳 | Syringe for painless oral local anesthesia |
JP6525991B2 (en) | 2013-07-17 | 2019-06-05 | サノフイSanofi | Assembly for a drug delivery device and method of operation thereof |
US10441724B2 (en) | 2013-07-17 | 2019-10-15 | Sanofi | Drive mechanism for a delivery device |
DK3021902T3 (en) * | 2013-07-17 | 2018-12-17 | Sanofi Sa | MEDICATION DELIVERY DEVICE |
US9849221B2 (en) * | 2013-10-04 | 2017-12-26 | Flex Fluidics, Llc | Inline pump with rear attachable syringe |
USD755372S1 (en) * | 2013-12-12 | 2016-05-03 | Daicel Corporation | Needleless syringe |
WO2015110532A1 (en) | 2014-01-27 | 2015-07-30 | Ucb Biopharma Sprl | Auto-injector |
WO2015110533A2 (en) | 2014-01-27 | 2015-07-30 | Ucb Biopharma Sprl | Auto-injector |
EP3099350B1 (en) | 2014-01-27 | 2019-06-12 | UCB Biopharma SPRL | Auto-injector |
CN105979983A (en) * | 2014-02-11 | 2016-09-28 | 史密斯医疗Asd公司 | Pump startup algorithms and related systems and methods |
EP3117240A1 (en) | 2014-03-13 | 2017-01-18 | Bracco Diagnostics Inc. | Real time nuclear isotope detection |
US10773032B2 (en) * | 2014-03-14 | 2020-09-15 | Shl Medical Ag | Monitoring device |
JP6261725B2 (en) * | 2014-04-25 | 2018-01-17 | パナソニックヘルスケアホールディングス株式会社 | Drug injection device |
US9517307B2 (en) | 2014-07-18 | 2016-12-13 | Kaleo, Inc. | Devices and methods for delivering opioid antagonists including formulations for naloxone |
US10971260B2 (en) | 2014-09-14 | 2021-04-06 | Becton, Dickinson And Company | System and method for capturing dose information |
US10704944B2 (en) | 2014-09-14 | 2020-07-07 | Becton, Dickinson And Company | System and method for capturing dose information |
EP3058970A1 (en) | 2015-02-19 | 2016-08-24 | Sanofi-Aventis Deutschland GmbH | Data collection device for attachment to an injection device |
CA2980004C (en) | 2015-03-24 | 2023-10-10 | Kaleo, Inc. | Devices and methods for delivering a lyophilized medicament |
CN104888315A (en) * | 2015-04-29 | 2015-09-09 | 安徽养和医疗器械设备有限公司 | Automatic injection syringe pusher |
EP3656423B1 (en) | 2015-06-09 | 2024-03-13 | Sanofi-Aventis Deutschland GmbH | Data collection apparatus for attachment to an injection device |
GB2556479B (en) | 2015-06-30 | 2022-09-07 | Kaleo Inc | Auto-injectors for administration of a medicament within a prefilled syringe |
JP6584172B2 (en) * | 2015-07-03 | 2019-10-02 | 株式会社アイカムス・ラボ | Discharge device |
US20170043139A1 (en) * | 2015-08-11 | 2017-02-16 | Vascular Solutions, Inc. | Fluid delivery or removal system |
US10279123B2 (en) | 2015-10-01 | 2019-05-07 | Noble International, Inc. | Microcartridge |
WO2017060899A2 (en) | 2015-10-05 | 2017-04-13 | E3D Agricultural Cooperative Association Ltd. | Infusion pump device and method for use thereof |
JP2016035597A (en) * | 2015-12-01 | 2016-03-17 | イーエイチエス レンズ フィリピン インク | Method for manufacturing polarizing plastic lens for spectacle |
AU2016383027B2 (en) | 2015-12-30 | 2021-04-15 | Ascendis Pharma A/S | Auto injector with charger safety |
JP6914962B2 (en) | 2015-12-30 | 2021-08-04 | アセンディス ファーマ エー/エス | Muzzle-loading automatic syringe for administering drugs |
AU2016383026B2 (en) | 2015-12-30 | 2021-06-17 | Ascendis Pharma A/S | Auto injector with detection of used cartridge and associated method |
PL3397324T3 (en) | 2015-12-30 | 2022-10-24 | Ascendis Pharma A/S | Auto injector with cartridge retention system |
WO2017114910A1 (en) * | 2015-12-30 | 2017-07-06 | Ascendis Pharma A/S | Auto injector with adaptable air-shot mechanism |
US20180092770A1 (en) * | 2016-03-14 | 2018-04-05 | Virchow Biotech Pvt. Ltd. | Sterile protective cover comprising a device for opthalmic delivery |
US20170258633A1 (en) * | 2016-03-14 | 2017-09-14 | Virchow Biotech Pvt. Ltd. | Novel device for ophthalmic delivery |
CN106080739A (en) * | 2016-06-20 | 2016-11-09 | 山东理工大学 | The controller that a kind of diabetes patient of auxiliary drives |
CN106004976A (en) * | 2016-06-30 | 2016-10-12 | 青岛大学附属医院 | Control device assisting in driving of diabetic patient |
US10709845B2 (en) | 2016-07-21 | 2020-07-14 | Amgen Inc. | Drug delivery device with a rotatable drive mechanism |
US11752254B2 (en) | 2016-09-20 | 2023-09-12 | Bracco Diagnostics Inc. | Radioisotope delivery system with multiple detectors to detect gamma and beta emissions |
JP6764319B2 (en) * | 2016-11-16 | 2020-09-30 | Phcホールディングス株式会社 | Drug injection device |
EP3558420A4 (en) | 2016-12-23 | 2020-05-27 | Kaleo, Inc. | Medicament delivery device and methods for delivering drugs to infants and children |
KR101958067B1 (en) | 2016-12-27 | 2019-07-04 | 최규동 | Monotoring and Magement System for Pen Type Injection Appartus |
WO2018136413A2 (en) | 2017-01-17 | 2018-07-26 | Kaleo, Inc. | Medicament delivery devices with wireless connectivity and event detection |
EP3348293A1 (en) * | 2017-01-17 | 2018-07-18 | Carebay Europe Ltd. | Medicament delivery device |
WO2018160425A1 (en) | 2017-02-28 | 2018-09-07 | Eli Lilly And Company | Dose detection and drug identification for a medication delivery device |
JP2020509872A (en) * | 2017-03-16 | 2020-04-02 | ノバルティス アーゲー | Puncture mechanism and cartridge puncture system |
JP6990234B2 (en) * | 2017-03-30 | 2022-01-12 | テルモ株式会社 | Chemical administration device and its operation method |
BR112019024511A2 (en) | 2017-05-23 | 2020-06-23 | Ascendis Pharma A/S | AUTOINJECTOR FOR THE ADMINISTRATION OF A MEDICINE, SYSTEM, AND METHOD TO CONTROL AN AUTOINJECTOR. |
US9789260B1 (en) * | 2017-05-25 | 2017-10-17 | Innovative Precision Instruments Limited | Device and system for drug information detection |
CN107412910A (en) * | 2017-06-26 | 2017-12-01 | 江苏德尔福医疗器械有限公司 | Syringe pump |
AU2018294519B2 (en) | 2017-06-29 | 2023-10-12 | Ascendis Pharma A/S | Auto injector with reconstitution handling support |
KR20190005572A (en) | 2017-07-07 | 2019-01-16 | 최규동 | Monotoring and Magement System for Pen Type Injection Appartus |
KR20190042830A (en) | 2017-10-17 | 2019-04-25 | 최규동 | Monotoring and Magement System for Pen Type Injection Appartus |
US11331022B2 (en) | 2017-10-24 | 2022-05-17 | Dexcom, Inc. | Pre-connected analyte sensors |
US20190120785A1 (en) | 2017-10-24 | 2019-04-25 | Dexcom, Inc. | Pre-connected analyte sensors |
WO2019121447A1 (en) * | 2017-12-18 | 2019-06-27 | Sanofi | Injection device with a remote control |
KR102510636B1 (en) | 2018-02-22 | 2023-03-17 | 일라이 릴리 앤드 캄파니 | Dose detection system module for medication delivery device |
US11810685B2 (en) | 2018-03-28 | 2023-11-07 | Bracco Diagnostics Inc. | Early detection of radioisotope generator end life |
US11850395B2 (en) * | 2018-05-17 | 2023-12-26 | Carefusion 303, Inc. | Syringe driver for infusion |
CN108969840A (en) * | 2018-06-11 | 2018-12-11 | 杭州光启医疗科技发展有限公司 | With the drug delivery system for weakening medicinal liquid flow fluctuation and pressure oscillation function |
CN108888826A (en) * | 2018-06-11 | 2018-11-27 | 杭州光启医疗科技发展有限公司 | Administration pump with successive administration function |
WO2020018433A1 (en) | 2018-07-16 | 2020-01-23 | Kaleo, Inc. | Medicament delivery devices with wireless connectivity and compliance detection |
TR201815876A2 (en) * | 2018-10-24 | 2018-11-21 | Hasan Kalyoncu Ueniversitesi | SPEAKING DIGITAL INSULIN PEN |
CN113226406B (en) * | 2018-12-27 | 2023-11-03 | 株式会社大赛璐 | Needleless injector |
KR102194269B1 (en) * | 2018-12-31 | 2020-12-22 | 권기만 | Portable refrigerated storage case for Pen Type Injection Appartus |
CN113301930B (en) * | 2019-01-16 | 2024-02-23 | 株式会社大赛璐 | Needleless injector |
CN111514412A (en) * | 2019-02-03 | 2020-08-11 | 杜建涛 | Painless anesthesia multifunctional automatic injection gun |
JP2022543523A (en) | 2019-08-09 | 2022-10-13 | カレオ,インコーポレイテッド | Device and method for delivery of substances in pre-filled syringes |
CN110507881B (en) * | 2019-09-04 | 2021-07-16 | 四川大学华西医院 | Multifunctional insulin injection pen |
EP4035710A4 (en) * | 2019-09-25 | 2022-09-14 | Shenzhen Mindray Scientific Co., Ltd. | Syringe pump, syringe pump system, syringe pump control method, and storage medium |
CN114845756A (en) * | 2019-10-28 | 2022-08-02 | 赛诺菲 | Haptic feedback for electronic medical devices |
KR102251405B1 (en) * | 2020-04-09 | 2021-05-12 | (주)풍림파마텍 | Automatic injector |
WO2021251965A1 (en) * | 2020-06-11 | 2021-12-16 | Bioworld Technology, Inc | Automated injection device for administering antigens to animals |
WO2022004876A1 (en) * | 2020-07-02 | 2022-01-06 | ヤーマン株式会社 | Liquid injection device, and system and cartridge unit therefor |
EP4226356A1 (en) * | 2020-10-05 | 2023-08-16 | Noble International, LLC | Medicament training device and system |
AU2021376242A1 (en) * | 2020-11-05 | 2023-06-22 | Dexcom, Inc. | Medicament injection pen for distinguishing between priming pen events and therapeutic pen events |
DE102021100818A1 (en) | 2021-01-15 | 2022-07-21 | B. Braun Melsungen Aktiengesellschaft | Devices for administering medicinal liquids and corresponding methods |
KR102600940B1 (en) * | 2022-01-13 | 2023-11-09 | 인제대학교 산학협력단 | Chamber unit for subcutaneous injection with drug storage and discharge function |
Family Cites Families (153)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US604257A (en) * | 1898-05-17 | Carl hermann | ||
US435173A (en) * | 1890-08-26 | Attachment for shelves | ||
AT65129B (en) | 1911-08-21 | 1914-06-10 | Wirth Beck & Knauss | Electrical device for starting and stopping a number of machines or other facilities from a remote point. |
AT115417B (en) | 1927-10-18 | 1929-12-27 | Aeg | X-ray tube, especially for very low voltages. |
US2866910A (en) * | 1954-11-09 | 1958-12-30 | Northrop Aircraft Inc | Pawl type incremental motor |
US3858581A (en) | 1973-07-02 | 1975-01-07 | Dean Kamen | Medication injection device |
NL172403C (en) | 1974-04-08 | 1983-09-01 | Duphar Int Res | SYRINGE WITH A CARTRIDGE AND A CARTRIDGE, WITH THE CARTRIDGE CONTAINING PATTERN LOCKERS, AND THE CARTRIDGE CONTAINER FOR AN INJECTION SYRINGE. |
US3964139A (en) * | 1975-06-16 | 1976-06-22 | Harvard Apparatus Company, Inc. | Syringe holder |
GB1601471A (en) * | 1975-12-10 | 1981-10-28 | Nat Res Dev | Dispensing apparatus |
DE2937066A1 (en) † | 1979-09-13 | 1981-03-26 | Clinicon International Gmbh, 6800 Mannheim | DOSING DEVICE |
GB2094628A (en) | 1981-03-10 | 1982-09-22 | Ealing The Corp | Infusion apparatus |
US4529401A (en) * | 1982-01-11 | 1985-07-16 | Cardiac Pacemakers, Inc. | Ambulatory infusion pump having programmable parameters |
US4435173A (en) | 1982-03-05 | 1984-03-06 | Delta Medical Industries | Variable rate syringe pump for insulin delivery |
DE8213933U1 (en) | 1982-05-13 | 1982-10-14 | Berlemann, Klaus, 4440 Rheine | SLIDING GATE |
SE432054B (en) | 1982-09-10 | 1984-03-19 | Anders Tamsen | PROGRAMMABLE INJECTION AND INFUSION DEVICE |
JPS59126608A (en) * | 1983-01-07 | 1984-07-21 | Aisin Seiki Co Ltd | Solenoid apparatus |
ATE65129T1 (en) | 1983-11-15 | 1991-07-15 | Dean L Kamen | VOLUMETRIC PUMP WITH REPLACEABLE TANK. |
EP0398394B1 (en) | 1983-11-15 | 1993-10-06 | KAMEN, Dean L. | Reservoir assembly for removable engagement with a motor drive |
US4749109A (en) * | 1983-11-15 | 1988-06-07 | Kamen Dean L | Volumetric pump with replaceable reservoir assembly |
US4648872A (en) | 1983-11-15 | 1987-03-10 | Kamen Dean L | Volumetric pump with replaceable reservoir assembly |
US4563175A (en) * | 1983-12-19 | 1986-01-07 | Lafond Margaret | Multiple syringe pump |
ES277095Y (en) | 1984-01-25 | 1985-02-16 | Fernandez-Tresguerres Hernandez Jesus A. | SUPPLIER-DISPENSER OF INJECTABLE PRODUCTS |
US4613327A (en) * | 1984-01-26 | 1986-09-23 | Tegrarian Haig V | Apparatus for infusing blood and other related fluids into a patient's body |
DK159526C (en) | 1984-11-01 | 1991-04-08 | Novo Nordisk As | DRIVE MECHANISM FOR AXIAL PROMOTION OF A Piston Rod, Especially For An Injection Spray |
US4812724A (en) † | 1984-11-13 | 1989-03-14 | Liebel-Flarsheim Corporation | Injector control |
US4681566A (en) * | 1984-11-30 | 1987-07-21 | Strato Medical Corporation | Infusion device |
US4627835A (en) | 1985-03-11 | 1986-12-09 | Strato Medical Corporation | Tubing assembly for infusion device |
US4652260A (en) † | 1985-03-11 | 1987-03-24 | Strato Medical Corporation | Infusion device |
JPH0645295B2 (en) | 1985-09-18 | 1994-06-15 | 日本電装株式会社 | Operating device for automobile air conditioner |
CH665955A5 (en) * | 1985-11-19 | 1988-06-30 | Universo Sa | Manually programmable injector - has interchangeable drug cartridge, and data input setting the valves which can be manually selected |
US5180371A (en) | 1986-05-30 | 1993-01-19 | Spintech, Inc. | Hypodermic anesthetic injection apparatus and method |
NL8701091A (en) * | 1987-05-08 | 1988-12-01 | Spruyt Hillen Bv | INJECTION PEN. |
GB2205460B (en) * | 1987-06-02 | 1991-09-04 | Multitone Electronics Plc | Local oscillators for radio receivers |
WO1988010383A1 (en) | 1987-06-19 | 1988-12-29 | The University Of Melbourne | Infusion pump and drive systems therefore |
US5207642A (en) | 1987-08-07 | 1993-05-04 | Baxter International Inc. | Closed multi-fluid delivery system and method |
US4925444A (en) * | 1987-08-07 | 1990-05-15 | Baxter Travenol Laboratories, Inc. | Closed multi-fluid delivery system and method |
US4976696A (en) | 1987-08-10 | 1990-12-11 | Becton, Dickinson And Company | Syringe pump and the like for delivering medication |
US4976686A (en) * | 1987-09-18 | 1990-12-11 | Schering Agrochemicals Limited | Implant gun |
US5041086A (en) | 1987-12-04 | 1991-08-20 | Pacesetter Infusion, Ltd. | Clinical configuration of multimode medication infusion system |
US5060658A (en) * | 1988-02-23 | 1991-10-29 | Vance Products Incorporated | Fine-needle aspiration cell sampling apparatus |
GB8809410D0 (en) | 1988-04-21 | 1988-05-25 | Welmed Ltd | Syringe pump |
US4921487A (en) * | 1988-09-21 | 1990-05-01 | Compagnie Financiere Saint. Nicolas | External device for injecting medicine |
DE3833821A1 (en) * | 1988-10-05 | 1990-04-12 | Braun Melsungen Ag | INJECTION DEVICE |
JPH0649069Y2 (en) | 1988-11-25 | 1994-12-12 | 株式会社竹中工務店 | Floor duct |
US4955868A (en) | 1988-11-28 | 1990-09-11 | Edward Klein | Disposable safety medical syringe |
DK68789A (en) | 1989-02-14 | 1990-08-15 | Novo Nordisk As | injector |
GB2229497B (en) | 1989-03-10 | 1992-06-03 | Graseby Medical Ltd | Infusion pump |
JP2739233B2 (en) * | 1989-04-19 | 1998-04-15 | 東レ・ダウコーニング・シリコーン株式会社 | Silicone granules containing mineral oil |
AU635262B2 (en) * | 1989-05-11 | 1993-03-18 | Bespak Plc | Pump apparatus for biomedical use |
US5085643A (en) * | 1989-06-02 | 1992-02-04 | Abbott Laboratories | Syringe, adaptor, and check valve combination for parenteral infuser |
US5060058A (en) | 1989-06-07 | 1991-10-22 | U.S. Philips Corporation | Modulation system for projection display |
CN2065888U (en) | 1989-07-18 | 1990-11-21 | 刘吉勇 | Safety monitor for induced abortion |
CN2065461U (en) | 1989-07-19 | 1990-11-14 | 朱苏豫 | Detecting and treating instrument for boilogy electric information |
CN2066747U (en) * | 1989-12-14 | 1990-12-05 | 张克针 | Intravenous injection automatic propelling device |
US5003239A (en) | 1990-01-11 | 1991-03-26 | Baxter International Inc. | Peristaltic pump monitoring device |
US5176502A (en) * | 1990-04-25 | 1993-01-05 | Becton, Dickinson And Company | Syringe pump and the like for delivering medication |
CN2085668U (en) * | 1990-09-05 | 1991-10-02 | 中国人民解放军271医院 | Pulse controllable syringe system for insuline |
US5709668A (en) | 1991-01-16 | 1998-01-20 | Senetek Plc | Automatic medicament injector employing non-coring needle |
US5360410A (en) | 1991-01-16 | 1994-11-01 | Senetek Plc | Safety syringe for mixing two-component medicaments |
US5078698A (en) | 1991-02-19 | 1992-01-07 | Sterling Drug Inc. | Axial eject hypodermic syringe holder |
US5176646A (en) * | 1991-02-19 | 1993-01-05 | Takayuki Kuroda | Motorized syringe pump |
US5106375A (en) | 1991-05-23 | 1992-04-21 | Ivac Corporation | Dynamic lead screw engagement and indicator |
US5425716A (en) * | 1991-08-09 | 1995-06-20 | Atom Kabushiki Kaisha | Infusion apparatus |
US5219099A (en) | 1991-09-06 | 1993-06-15 | California Institute Of Technology | Coaxial lead screw drive syringe pump |
US5321392A (en) * | 1991-10-18 | 1994-06-14 | Baxter International Inc. | Infusion pump with battery back-up |
DK175491D0 (en) | 1991-10-18 | 1991-10-18 | Novo Nordisk As | APPARATUS |
US5271527A (en) | 1992-04-02 | 1993-12-21 | Habley Medical Technology Corporation | Reusable pharmaceutical dispenser with full stroke indicator |
US5423752A (en) | 1992-07-31 | 1995-06-13 | Habley Medical Technology Corporation | Variable proportion dispenser with cartridge replacement assembly |
JPH05277181A (en) | 1992-04-03 | 1993-10-26 | Sharp Corp | Infusion device |
JPH067445A (en) * | 1992-06-25 | 1994-01-18 | Matsushita Electric Works Ltd | Pen type injection device |
IL107038A (en) | 1992-10-05 | 1997-04-15 | Senetek Plc | Medicament injectors and methods for injection using same |
CA2125693C (en) | 1992-10-15 | 2005-05-03 | Alan D. Ford | An infusion pump with an electronically loadable drug library |
US5448117A (en) | 1993-02-25 | 1995-09-05 | Consulier Engineering, Inc. | Stepper motor |
DE4310808C2 (en) | 1993-04-02 | 1995-06-22 | Boehringer Mannheim Gmbh | Liquid dosing system |
CA2129284C (en) * | 1993-11-24 | 1999-03-09 | Kenneth J. Niehoff | Controlling plunger drives for fluid injection in animals |
US5442669A (en) * | 1993-12-27 | 1995-08-15 | Medin; David L. | Perishable good integrity indicator |
CA2181802C (en) | 1994-02-14 | 2006-10-10 | Peter Michael Knauer | Self administered injection pen apparatus and method |
US5514097A (en) | 1994-02-14 | 1996-05-07 | Genentech, Inc. | Self administered injection pen apparatus and method |
US5482446A (en) † | 1994-03-09 | 1996-01-09 | Baxter International Inc. | Ambulatory infusion pump |
US5536249A (en) * | 1994-03-09 | 1996-07-16 | Visionary Medical Products, Inc. | Pen-type injector with a microprocessor and blood characteristic monitor |
US5460490A (en) * | 1994-05-19 | 1995-10-24 | Linvatec Corporation | Multi-purpose irrigation/aspiration pump system |
WO1996005878A1 (en) | 1994-08-24 | 1996-02-29 | Eli Lilly Japan Kabushiki Kaisha | Injection apparatus |
US6397098B1 (en) * | 1994-09-21 | 2002-05-28 | Medrad, Inc. | Data communication and control for medical imaging systems |
US5533981A (en) * | 1994-10-06 | 1996-07-09 | Baxter International Inc. | Syringe infusion pump having a syringe plunger sensor |
SE510420C2 (en) | 1994-11-14 | 1999-05-25 | Cma Microdialysis Ab | Infusion and microdialysis pump |
CN2209532Y (en) * | 1994-12-31 | 1995-10-11 | 纪文龙 | Electric-driving fluid expeller for intravenous injection |
US5637093A (en) | 1995-03-06 | 1997-06-10 | Sabratek Corporation | Infusion pump with selective backlight |
US5843014A (en) * | 1995-03-24 | 1998-12-01 | Alza Corporation | Display for an electrotransport delivery device |
US6099502A (en) | 1995-04-20 | 2000-08-08 | Acist Medical Systems, Inc. | Dual port syringe |
US5722956A (en) * | 1995-08-24 | 1998-03-03 | The General Hospital Corporation | Multi-dose syringe driver |
AU1860697A (en) | 1995-09-08 | 1997-07-28 | Visionary Medical Products Corporation | Pen-type injector drive mechanism |
US5989221A (en) | 1995-10-20 | 1999-11-23 | Pharmacia & Upjohn Ab | Arrangement in electronically controlled injection devices |
SE9503685D0 (en) | 1995-10-20 | 1995-10-20 | Pharmacia Ab | Arrangement in electronically controlled injection devices |
US6159161A (en) | 1995-10-20 | 2000-12-12 | Hodosh; Milton | Microprocessor-controlled fluid dispensing apparatus |
AUPN707195A0 (en) * | 1995-12-12 | 1996-01-11 | University Of Melbourne, The | Field programmable intravenous infusion system |
US5671285A (en) * | 1995-12-13 | 1997-09-23 | Newman; Bruce D. | Secure communication system |
CA2241631C (en) | 1995-12-28 | 2002-10-15 | Bio-Plexus, Inc. | Needle holder for fluid collection and/or injection system |
US5966671A (en) * | 1996-01-03 | 1999-10-12 | Motorola, Inc. | Radiotelephone having an auxiliary actuator and method for operating said radiotelephone |
JP3892095B2 (en) | 1996-01-23 | 2007-03-14 | テルモ株式会社 | Syringe |
EP0787501B1 (en) | 1996-01-23 | 2003-04-09 | Terumo Kabushiki Kaisha | Injector |
ES2200155T3 (en) | 1996-02-23 | 2004-03-01 | Novo Nordisk A/S | SYRINGE WITH AN ELECTRONIC REPRESENTATION OF THE PARAMETERS. |
PL185605B1 (en) | 1996-03-12 | 2003-06-30 | Novo Nordisk As | Injection making instrument with electronic pre-setting of specific doses |
GB9606829D0 (en) | 1996-03-30 | 1996-06-05 | Jeffrey Peter | Supplying materials etc |
CN2273583Y (en) * | 1996-04-29 | 1998-02-04 | 刘世棣 | Full automatic and magnetic actuated piston machine for syringe |
IL127618A (en) | 1996-07-01 | 2006-09-05 | Pfizer Health Ab | Injection device and method for its operation |
CN1225023A (en) | 1996-07-05 | 1999-08-04 | 诺沃挪第克公司 | Dose setting device |
EP0910419B1 (en) | 1996-07-05 | 2004-05-26 | Novo Nordisk A/S | Dose setting device |
US6110149A (en) | 1996-09-13 | 2000-08-29 | Novo Nordisk A/S | Syringe |
US5868710A (en) | 1996-11-22 | 1999-02-09 | Liebel Flarsheim Company | Medical fluid injector |
JP3288943B2 (en) | 1996-12-06 | 2002-06-04 | スーガン株式会社 | Medical injector head |
US6558351B1 (en) * | 1999-06-03 | 2003-05-06 | Medtronic Minimed, Inc. | Closed loop system for controlling insulin infusion |
SE9702872D0 (en) | 1997-08-06 | 1997-08-06 | Pharmacia & Upjohn Ab | Automated delivery device and method for its operation |
US5957896A (en) | 1997-08-11 | 1999-09-28 | Becton, Dickinson And Company | Medication delivery pen |
AU9104498A (en) * | 1997-08-22 | 1999-03-16 | Deka Products Limited Partnership | System and method for intelligent admixture and delivery of medications |
US6636732B1 (en) * | 1998-03-19 | 2003-10-21 | Securealert, Inc. | Emergency phone with single-button activation |
US6200289B1 (en) | 1998-04-10 | 2001-03-13 | Milestone Scientific, Inc. | Pressure/force computer controlled drug delivery system and the like |
CZ290250B6 (en) | 1998-04-17 | 2002-06-12 | Josef Bure© | Force converter for internal combustion engines |
US6302855B1 (en) * | 1998-05-20 | 2001-10-16 | Novo Nordisk A/S | Medical apparatus for use by a patient for medical self treatment of diabetes |
KR100301657B1 (en) | 1998-08-14 | 2001-10-27 | 최수봉 | Control method of insulin syringe with pseudo mode |
US6554798B1 (en) | 1998-08-18 | 2003-04-29 | Medtronic Minimed, Inc. | External infusion device with remote programming, bolus estimator and/or vibration alarm capabilities |
DE69923858T2 (en) | 1998-10-29 | 2006-01-12 | Medtronic MiniMed, Inc., Northridge | COMPACT PUMP DRIVE SYSTEM |
US6248093B1 (en) | 1998-10-29 | 2001-06-19 | Minimed Inc. | Compact pump drive system |
US6379337B1 (en) | 1998-12-22 | 2002-04-30 | Owais Mohammad M. B. B. S. | Retractable safety needles for medical applications |
US6645177B1 (en) | 1999-02-09 | 2003-11-11 | Alaris Medical Systems, Inc. | Directly engaged syringe driver system |
US20040158193A1 (en) * | 1999-02-10 | 2004-08-12 | Baxter International Inc. | Medical apparatus using selective graphical interface |
SE9901736D0 (en) | 1999-05-12 | 1999-05-12 | Pharmacia & Upjohn Ab | Injectino device and method for ITS operation |
DE19925904C1 (en) | 1999-06-07 | 2001-02-01 | Disetronic Licensing Ag | Unit for subcutaneous application of an injectable product comprises a system which indicates whether the protection sleeve of the injection needle is in its fully retracted position |
US6752787B1 (en) | 1999-06-08 | 2004-06-22 | Medtronic Minimed, Inc., | Cost-sensitive application infusion device |
US6423035B1 (en) * | 1999-06-18 | 2002-07-23 | Animas Corporation | Infusion pump with a sealed drive mechanism and improved method of occlusion detection |
US6277099B1 (en) | 1999-08-06 | 2001-08-21 | Becton, Dickinson And Company | Medication delivery pen |
TW453884B (en) * | 1999-09-16 | 2001-09-11 | Novo Nordisk As | Dose setting limiter |
AU7839900A (en) | 1999-09-29 | 2001-04-30 | Sterling Medivations, Inc. | Reusable medication delivery device |
KR20020036860A (en) | 1999-10-12 | 2002-05-16 | 한센 핀 베네드, 안네 제헤르, 웨이콥 마리안느 | Air shot mechanism for electronic injection devices |
DE29918149U1 (en) * | 1999-10-15 | 1999-12-30 | Volmer Wolfgang | Insulin delivery device |
US6585698B1 (en) | 1999-11-01 | 2003-07-01 | Becton, Dickinson & Company | Electronic medical delivery pen having a multifunction actuator |
US6958053B1 (en) * | 1999-11-24 | 2005-10-25 | Medrad, Inc. | Injector providing drive member advancement and engagement with syringe plunger, and method of connecting a syringe to an injector |
WO2001037904A2 (en) | 1999-11-24 | 2001-05-31 | Medrad, Inc. | Injectors, injector systems and injector control |
US6873268B2 (en) * | 2000-01-21 | 2005-03-29 | Medtronic Minimed, Inc. | Microprocessor controlled ambulatory medical apparatus with hand held communication device |
US6485465B2 (en) | 2000-03-29 | 2002-11-26 | Medtronic Minimed, Inc. | Methods, apparatuses, and uses for infusion pump fluid pressure and force detection |
US6544229B1 (en) * | 2000-05-01 | 2003-04-08 | Baxter International Inc | Linearly motile infusion pump |
US6623459B1 (en) | 2000-05-05 | 2003-09-23 | Safety Syringes, Inc. | Passive needle guard for syringes |
US6716198B2 (en) * | 2000-05-18 | 2004-04-06 | Novo Nordisk A/S | Injection device |
DE10046279A1 (en) | 2000-09-19 | 2002-04-04 | Disetronic Licensing Ag | Device for the dosed administration of an injectable product |
US20050273079A1 (en) † | 2000-10-10 | 2005-12-08 | Hohlfelder Ingrid E | Fluid material dispensing syringe |
JP2002121404A (en) * | 2000-10-19 | 2002-04-23 | Polymatech Co Ltd | Heat-conductive polymer sheet |
IL156245A0 (en) | 2000-12-22 | 2004-01-04 | Dca Design Int Ltd | Drive mechanism for an injection device |
US6613280B2 (en) * | 2001-03-20 | 2003-09-02 | Therox, Inc. | Disposable cartridge for producing gas-enriched fluids |
US6723072B2 (en) | 2002-06-06 | 2004-04-20 | Insulet Corporation | Plunger assembly for patient infusion device |
CN1301184C (en) | 2003-12-16 | 2007-02-21 | 汪开庆 | Optical grinding machine and method for processing sapphire crystal substrate for semiconductor use |
DE102004058408B4 (en) | 2004-12-03 | 2013-10-31 | Byk Gardner Gmbh | Device for determining surface properties |
US7660628B2 (en) | 2005-03-23 | 2010-02-09 | Cardiac Pacemakers, Inc. | System to provide myocardial and neural stimulation |
US8778375B2 (en) | 2005-04-29 | 2014-07-15 | Advanced Cardiovascular Systems, Inc. | Amorphous poly(D,L-lactide) coating |
DE102005021371A1 (en) | 2005-05-04 | 2006-11-23 | Autoliv Development Ab | airbag |
-
2000
- 2000-12-21 IL IL15624500A patent/IL156245A0/en active IP Right Grant
- 2000-12-22 GB GBGB0031466.6A patent/GB0031466D0/en not_active Ceased
-
2001
- 2001-12-21 US US10/433,643 patent/US8128603B2/en active Active
- 2001-12-21 ES ES01272097T patent/ES2283375T3/en not_active Expired - Lifetime
- 2001-12-21 AT AT01272107T patent/ATE295749T1/en active
- 2001-12-21 ES ES01273459T patent/ES2240348T3/en not_active Expired - Lifetime
- 2001-12-21 PT PT01272101T patent/PT1353713E/en unknown
- 2001-12-21 JP JP2002552614A patent/JP4150589B2/en not_active Expired - Lifetime
- 2001-12-21 DE DE60112472.3T patent/DE60112472T3/en not_active Expired - Lifetime
- 2001-12-21 US US10/433,646 patent/US8469922B2/en active Active
- 2001-12-21 BR BR0116294-2A patent/BR0116294A/en not_active IP Right Cessation
- 2001-12-21 AT AT01272106T patent/ATE294002T1/en active
- 2001-12-21 CA CA002430925A patent/CA2430925A1/en not_active Abandoned
- 2001-12-21 PT PT01272093T patent/PT1353712E/en unknown
- 2001-12-21 DE DE60119164T patent/DE60119164T2/en not_active Expired - Lifetime
- 2001-12-21 BR BRPI0116273-0A patent/BR0116273B1/en not_active IP Right Cessation
- 2001-12-21 MX MXPA03005593A patent/MXPA03005593A/en active IP Right Grant
- 2001-12-21 PT PT01272098T patent/PT1353715E/en unknown
- 2001-12-21 EP EP01272097.5A patent/EP1349593B2/en not_active Expired - Lifetime
- 2001-12-21 KR KR1020037008254A patent/KR100826218B1/en not_active IP Right Cessation
- 2001-12-21 BR BRPI0116279-9A patent/BR0116279B1/en not_active IP Right Cessation
- 2001-12-21 CA CA002430938A patent/CA2430938C/en not_active Expired - Fee Related
- 2001-12-21 CA CA002430917A patent/CA2430917C/en not_active Expired - Fee Related
- 2001-12-21 AT AT01273458T patent/ATE300324T1/en active
- 2001-12-21 ES ES01272092T patent/ES2240340T3/en not_active Expired - Lifetime
- 2001-12-21 IL IL15624001A patent/IL156240A0/en active IP Right Grant
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- 2001-12-21 WO PCT/GB2001/005743 patent/WO2002051475A1/en active IP Right Grant
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- 2001-12-21 MX MXPA03005590A patent/MXPA03005590A/en active IP Right Grant
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- 2001-12-21 IL IL15624601A patent/IL156246A0/en unknown
- 2001-12-21 US US10/433,645 patent/US20040054328A1/en not_active Abandoned
- 2001-12-21 DK DK01273459T patent/DK1349596T3/en active
- 2001-12-21 US US10/433,648 patent/US20040097873A1/en not_active Abandoned
- 2001-12-21 AT AT01273459T patent/ATE294602T1/en active
- 2001-12-21 PT PT01272097T patent/PT1349593E/en unknown
- 2001-12-21 WO PCT/GB2001/005710 patent/WO2002051478A1/en not_active Application Discontinuation
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- 2001-12-21 MX MXPA03005584A patent/MXPA03005584A/en active IP Right Grant
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- 2001-12-21 PT PT01272095T patent/PT1349592E/en unknown
- 2001-12-21 PT PT01272092T patent/PT1349587E/en unknown
- 2001-12-21 KR KR1020037008405A patent/KR100788319B1/en not_active IP Right Cessation
- 2001-12-21 EP EP01272101A patent/EP1353713B1/en not_active Expired - Lifetime
- 2001-12-21 AT AT01272093T patent/ATE342076T1/en active
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- 2001-12-21 ES ES01273458T patent/ES2246289T3/en not_active Expired - Lifetime
- 2001-12-21 WO PCT/GB2001/005721 patent/WO2002051473A1/en active IP Right Grant
- 2001-12-21 DK DK01272101T patent/DK1353713T3/en active
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- 2001-12-21 KR KR1020037008401A patent/KR100826221B1/en not_active IP Right Cessation
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- 2001-12-21 DK DK01273458T patent/DK1349595T3/en active
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- 2001-12-21 CN CNA01821164XA patent/CN1482933A/en active Pending
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- 2001-12-21 MX MXPA03005592A patent/MXPA03005592A/en active IP Right Grant
- 2001-12-21 DE DE60112326T patent/DE60112326T2/en not_active Expired - Lifetime
- 2001-12-21 MX MXPA03005591A patent/MXPA03005591A/en active IP Right Grant
- 2001-12-21 DK DK01272106T patent/DK1351728T3/en active
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- 2001-12-21 MX MXPA03005576A patent/MXPA03005576A/en active IP Right Grant
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- 2001-12-21 WO PCT/GB2001/005712 patent/WO2002051480A1/en active IP Right Grant
- 2001-12-21 BR BRPI0116275-6A patent/BR0116275B1/en not_active IP Right Cessation
- 2001-12-21 KR KR1020037008255A patent/KR100788316B1/en not_active IP Right Cessation
- 2001-12-21 AT AT01272097T patent/ATE356644T1/en active
- 2001-12-21 ES ES01272095T patent/ES2240341T3/en not_active Expired - Lifetime
- 2001-12-21 EP EP01272095A patent/EP1349592B1/en not_active Expired - Lifetime
- 2001-12-21 IL IL15625101A patent/IL156251A0/en active IP Right Grant
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- 2001-12-21 US US10/433,782 patent/US7699815B2/en not_active Expired - Lifetime
- 2001-12-21 ES ES01272094.2T patent/ES2247008T5/en not_active Expired - Lifetime
- 2001-12-21 BR BRPI0116276-4A patent/BR0116276B1/en not_active IP Right Cessation
- 2001-12-21 AU AU2002216254A patent/AU2002216254B2/en not_active Ceased
- 2001-12-21 KR KR1020037008407A patent/KR100788323B1/en not_active IP Right Cessation
- 2001-12-21 PT PT01273459T patent/PT1349596E/en unknown
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- 2001-12-21 AT AT01272092T patent/ATE294599T1/en active
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- 2001-12-21 DK DK01272107T patent/DK1349588T3/en active
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- 2001-12-21 WO PCT/GB2001/005709 patent/WO2002051477A1/en active IP Right Grant
- 2001-12-21 US US10/433,647 patent/US6969370B2/en not_active Expired - Lifetime
- 2001-12-21 KR KR1020037008403A patent/KR100826222B1/en not_active IP Right Cessation
- 2001-12-21 CA CA002430922A patent/CA2430922C/en not_active Expired - Fee Related
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- 2001-12-21 MX MXPA03005577A patent/MXPA03005577A/en active IP Right Grant
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- 2001-12-21 EP EP01272092A patent/EP1349587B1/en not_active Expired - Lifetime
- 2001-12-21 CN CNB018210961A patent/CN1290587C/en not_active Expired - Lifetime
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- 2001-12-21 CN CNB018210821A patent/CN1325127C/en not_active Expired - Lifetime
- 2001-12-21 WO PCT/GB2001/005726 patent/WO2002051481A1/en active IP Right Grant
- 2001-12-21 US US10/433,650 patent/US7052484B2/en not_active Expired - Lifetime
- 2001-12-21 DE DE60110638T patent/DE60110638T2/en not_active Expired - Lifetime
- 2001-12-21 KR KR1020037008402A patent/KR100788318B1/en not_active IP Right Cessation
- 2001-12-21 MX MXPA03005578A patent/MXPA03005578A/en active IP Right Grant
- 2001-12-21 PT PT01272104T patent/PT1349594E/en unknown
- 2001-12-21 WO PCT/GB2001/005704 patent/WO2002051471A1/en active IP Right Grant
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- 2001-12-21 WO PCT/GB2001/005741 patent/WO2002051474A1/en active IP Right Grant
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- 2001-12-21 AT AT01272101T patent/ATE324131T1/en active
- 2001-12-21 EP EP01273458A patent/EP1349595B1/en not_active Expired - Lifetime
- 2001-12-21 WO PCT/GB2001/005747 patent/WO2002058767A1/en active IP Right Grant
- 2001-12-21 IL IL15623801A patent/IL156238A0/en active IP Right Grant
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- 2001-12-21 IL IL15623901A patent/IL156239A0/en active IP Right Grant
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- 2001-12-21 DK DK01272098T patent/DK1353715T3/en active
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- 2001-12-21 BR BRPI0116277-2A patent/BR0116277B1/en not_active IP Right Cessation
- 2001-12-21 DK DK01272092T patent/DK1349587T3/en active
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- 2001-12-21 AT AT01272098T patent/ATE294603T1/en active
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- 2001-12-21 WO PCT/GB2001/005693 patent/WO2002058766A1/en active IP Right Grant
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- 2001-12-21 KR KR1020037008257A patent/KR100788317B1/en not_active IP Right Cessation
- 2001-12-21 DK DK01272094.2T patent/DK1349591T4/en active
- 2001-12-21 US US10/433,649 patent/US6942646B2/en not_active Expired - Lifetime
- 2001-12-21 WO PCT/GB2001/005705 patent/WO2002051472A1/en active IP Right Grant
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- 2001-12-21 AT AT01272094T patent/ATE300967T1/en active
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- 2001-12-21 KR KR1020037008404A patent/KR100826227B1/en not_active IP Right Cessation
- 2001-12-21 AT AT01272104T patent/ATE294601T1/en active
- 2001-12-21 DK DK01272097.5T patent/DK1349593T4/en active
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- 2001-12-21 MX MXPA03005575A patent/MXPA03005575A/en active IP Right Grant
- 2001-12-21 EP EP01272094.2A patent/EP1349591B2/en not_active Expired - Lifetime
- 2001-12-21 IL IL15624301A patent/IL156243A0/en unknown
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- 2001-12-21 IL IL15624201A patent/IL156242A0/en active IP Right Grant
- 2001-12-21 AT AT01272095T patent/ATE294600T1/en active
- 2001-12-21 JP JP2002552616A patent/JP4614621B2/en not_active Expired - Lifetime
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2003
- 2003-06-01 IL IL156240A patent/IL156240A/en not_active IP Right Cessation
- 2003-06-01 IL IL156242A patent/IL156242A/en not_active IP Right Cessation
- 2003-06-01 IL IL156245A patent/IL156245A/en not_active IP Right Cessation
- 2003-06-01 IL IL156251A patent/IL156251A/en not_active IP Right Cessation
- 2003-06-01 IL IL156243A patent/IL156243A/en not_active IP Right Cessation
- 2003-06-01 IL IL156238A patent/IL156238A/en not_active IP Right Cessation
- 2003-06-01 IL IL156244A patent/IL156244A/en not_active IP Right Cessation
- 2003-06-01 IL IL156239A patent/IL156239A/en not_active IP Right Cessation
- 2003-06-02 IL IL156270A patent/IL156270A/en not_active IP Right Cessation
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2004
- 2004-04-08 HK HK04102499A patent/HK1059585A1/en not_active IP Right Cessation
- 2004-04-08 HK HK04102497A patent/HK1059583A1/en not_active IP Right Cessation
- 2004-04-08 HK HK04102494A patent/HK1059580A1/en not_active IP Right Cessation
- 2004-04-08 HK HK04102495A patent/HK1059581A1/en not_active IP Right Cessation
- 2004-04-08 HK HK04102493A patent/HK1059579A1/en not_active IP Right Cessation
- 2004-04-08 HK HK04102498A patent/HK1059584A1/en not_active IP Right Cessation
- 2004-04-08 HK HK04102520A patent/HK1059586A1/en not_active IP Right Cessation
- 2004-04-08 HK HK04102496A patent/HK1059582A1/en not_active IP Right Cessation
- 2004-04-14 HK HK04102605A patent/HK1059747A1/en not_active IP Right Cessation
- 2004-04-21 HK HK04102786A patent/HK1059903A1/en not_active IP Right Cessation
- 2004-04-21 HK HK04102785A patent/HK1059902A1/en not_active IP Right Cessation
- 2004-04-22 HK HK04102831A patent/HK1059904A1/en not_active IP Right Cessation
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2006
- 2006-07-26 CY CY20061101037T patent/CY1106128T1/en unknown
- 2006-12-20 CY CY20061101821T patent/CY1106295T1/en unknown
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2007
- 2007-04-26 AU AU2007201951A patent/AU2007201951B2/en not_active Ceased
- 2007-05-01 AU AU2007202032A patent/AU2007202032B2/en not_active Ceased
- 2007-06-11 CY CY20071100777T patent/CY1106652T1/en unknown
-
2008
- 2008-10-01 JP JP2008256767A patent/JP4955637B2/en not_active Expired - Lifetime
-
2009
- 2009-08-14 JP JP2009188006A patent/JP5054739B2/en not_active Expired - Lifetime
-
2010
- 2010-11-19 JP JP2010258513A patent/JP5461368B2/en not_active Expired - Lifetime
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