CA2413806A1 - Electrokinetic delivery device - Google Patents

Electrokinetic delivery device Download PDF

Info

Publication number
CA2413806A1
CA2413806A1 CA002413806A CA2413806A CA2413806A1 CA 2413806 A1 CA2413806 A1 CA 2413806A1 CA 002413806 A CA002413806 A CA 002413806A CA 2413806 A CA2413806 A CA 2413806A CA 2413806 A1 CA2413806 A1 CA 2413806A1
Authority
CA
Canada
Prior art keywords
pad
electrode
medicament
contained
applicator
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002413806A
Other languages
French (fr)
Other versions
CA2413806C (en
Inventor
Julian L. Henley
Kuo Wei Chang
Joseph Potter
Dennis I. Goldberg
Christopher H. Porter
V. Lorenzo Porcelli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biophoretic Therapeutic Systems LLC
Original Assignee
Biophoretic Therapeutic Systems, Llc
Julian L. Henley
Kuo Wei Chang
Joseph Potter
Dennis I. Goldberg
Christopher H. Porter
V. Lorenzo Porcelli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biophoretic Therapeutic Systems, Llc, Julian L. Henley, Kuo Wei Chang, Joseph Potter, Dennis I. Goldberg, Christopher H. Porter, V. Lorenzo Porcelli filed Critical Biophoretic Therapeutic Systems, Llc
Publication of CA2413806A1 publication Critical patent/CA2413806A1/en
Application granted granted Critical
Publication of CA2413806C publication Critical patent/CA2413806C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0428Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/20Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0428Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432Anode and cathode
    • A61N1/0436Material of the electrode
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0428Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432Anode and cathode
    • A61N1/044Shape of the electrode
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0428Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0448Drug reservoir

Abstract

An electrokinetic delivery or diagnostic device (10) for self-administration of a medicament. The device includes a housing (12) containing a power supply (14), a first active electrode (24) and a ground tactile electrode (30). An applicator (40) includes a pad (44) for containing medicament for overlying the first electrode (24) of the device (10). The medicament may be applied by the user to the pad (44), contained within the pad (44) or contained in rupturable capsules (56) within the pad (44), together with a hydrogel if necessary for imparting electrical conductivity. In another form, the applicator (70) is self-contained, having a power supply (74), a first electrode (78) overlying a pad (44a) and a ground electrode (80) from the opposite side of the pad (44a) whereby an individual presses the pad (44a) against the treatment site to complete the electrical circuit and electrokinetically drive the medicament into the treatment site.
CA002413806A 2000-05-31 2001-05-21 Electrokinetic delivery device Expired - Fee Related CA2413806C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/584,138 US6477410B1 (en) 2000-05-31 2000-05-31 Electrokinetic delivery of medicaments
US09/584,138 2000-05-31
PCT/US2001/016069 WO2001091853A1 (en) 2000-05-31 2001-05-21 Electrokinetic delivery device

Publications (2)

Publication Number Publication Date
CA2413806A1 true CA2413806A1 (en) 2001-12-06
CA2413806C CA2413806C (en) 2006-09-19

Family

ID=24336071

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002413806A Expired - Fee Related CA2413806C (en) 2000-05-31 2001-05-21 Electrokinetic delivery device

Country Status (11)

Country Link
US (5) US6477410B1 (en)
EP (2) EP2277584A1 (en)
JP (1) JP4199457B2 (en)
CN (1) CN1287877C (en)
AU (5) AU2001274851B2 (en)
BR (1) BR0111288A (en)
CA (1) CA2413806C (en)
HK (1) HK1054338A1 (en)
MX (1) MXPA02011842A (en)
RU (1) RU2268075C2 (en)
WO (1) WO2001091853A1 (en)

Families Citing this family (315)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6702949B2 (en) 1997-10-24 2004-03-09 Microdiffusion, Inc. Diffuser/emulsifier for aquaculture applications
US20110075507A1 (en) * 1997-10-24 2011-03-31 Revalesio Corporation Diffuser/emulsifier
US7127285B2 (en) * 1999-03-12 2006-10-24 Transport Pharmaceuticals Inc. Systems and methods for electrokinetic delivery of a substance
US6477410B1 (en) * 2000-05-31 2002-11-05 Biophoretic Therapeutic Systems, Llc Electrokinetic delivery of medicaments
US6792306B2 (en) * 2000-03-10 2004-09-14 Biophoretic Therapeutic Systems, Llc Finger-mounted electrokinetic delivery system for self-administration of medicaments and methods therefor
US6641591B1 (en) 1999-08-26 2003-11-04 John H. Shadduck Instruments and techniques for controlled removal of epidermal layers
US6565882B2 (en) * 2000-02-24 2003-05-20 Advancis Pharmaceutical Corp Antibiotic composition with inhibitor
US6544555B2 (en) 2000-02-24 2003-04-08 Advancis Pharmaceutical Corp. Antibiotic product, use and formulation thereof
US20040111050A1 (en) * 2000-04-14 2004-06-10 Gregory Smedley Implantable ocular pump to reduce intraocular pressure
US20050049578A1 (en) * 2000-04-14 2005-03-03 Hosheng Tu Implantable ocular pump to reduce intraocular pressure
US6541014B2 (en) * 2000-10-13 2003-04-01 Advancis Pharmaceutical Corp. Antiviral product, use and formulation thereof
US20020068078A1 (en) 2000-10-13 2002-06-06 Rudnic Edward M. Antifungal product, use and formulation thereof
US7431710B2 (en) 2002-04-08 2008-10-07 Glaukos Corporation Ocular implants with anchors and methods thereof
US7488303B1 (en) * 2002-09-21 2009-02-10 Glaukos Corporation Ocular implant with anchor and multiple openings
US20020189947A1 (en) 2001-06-13 2002-12-19 Eksigent Technologies Llp Electroosmotic flow controller
US7465382B2 (en) * 2001-06-13 2008-12-16 Eksigent Technologies Llc Precision flow control system
AU2002316724A1 (en) * 2001-07-20 2003-03-03 Iomed, Inc. Ophthalmic use of 5 fluorourcil
FR2830766B1 (en) * 2001-10-12 2004-03-12 Optis France Sa DEVICE   OF   ISSUE   OF   DRUGS   THROUGH   IONTOPHORESIS   TRANSPALPEBRALE
JP4394444B2 (en) * 2001-10-24 2010-01-06 パワー ペーパー リミティド Devices and methods for controlled intradermal delivery of active agents
US9084879B2 (en) 2002-01-22 2015-07-21 Encore Medical Asset Corporation Method and device for the iontophoretic delivery of a drug
US20030144625A1 (en) * 2002-01-28 2003-07-31 Garry Sherman Method and apparatus for the treatment of infections of the nail matrix and nail plate
AU2007203591B2 (en) * 2002-04-08 2010-07-29 Biophoretic Therapeutic Systems, Llc Finger-mounted electrokinetic delivery system for self-administration of medicaments
US7483736B2 (en) * 2002-04-24 2009-01-27 Rocky Mountain Biosystems, Inc. Feedback control device for transcutaneous drug delivery and uses therefor
US7517440B2 (en) 2002-07-17 2009-04-14 Eksigent Technologies Llc Electrokinetic delivery systems, devices and methods
US7235164B2 (en) * 2002-10-18 2007-06-26 Eksigent Technologies, Llc Electrokinetic pump having capacitive electrodes
FR2844719B1 (en) * 2002-09-24 2004-11-19 Francois Duret ELECTROCHEMICAL DEVICE FOR BLEACHING A BODY
US20040267240A1 (en) * 2003-01-29 2004-12-30 Yossi Gross Active drug delivery in the gastrointestinal tract
CA2514392A1 (en) * 2003-01-29 2004-08-12 E-Pill Pharma Ltd. Active drug delivery in the gastrointestinal tract
US7220597B2 (en) * 2003-01-30 2007-05-22 Zin Benedict L Assay test device and method of making same
US20040158194A1 (en) * 2003-02-06 2004-08-12 Wolff Andy And Beiski Ben Z. Oral devices and methods for controlled drug release
US20040199204A1 (en) * 2003-02-14 2004-10-07 Voegele James W. Multifunctional surgical instrument
US20040225217A1 (en) * 2003-02-14 2004-11-11 Voegele James W. Fingertip ultrasound medical instrument
US20040193211A1 (en) * 2003-02-14 2004-09-30 Voegele James W. Fingertip surgical instruments
US8118722B2 (en) 2003-03-07 2012-02-21 Neuronetics, Inc. Reducing discomfort caused by electrical stimulation
US7153256B2 (en) * 2003-03-07 2006-12-26 Neuronetics, Inc. Reducing discomfort caused by electrical stimulation
FR2855761B1 (en) * 2003-06-03 2006-02-24 Optis France Sa OCULAR DEVICE FOR VARIABLE DELIVERY OF ACTIVE PRINCIPLES BY IONTOPHORESIS
WO2004112689A2 (en) * 2003-06-23 2004-12-29 Transpharma Medical Ltd. Transdermal delivery system for cosmetic agents
US20040267283A1 (en) 2003-06-25 2004-12-30 Daniela Mavor Method, device and kit for body decoration
US7477940B2 (en) * 2003-06-30 2009-01-13 J&J Consumer Companies, Inc. Methods of administering an active agent to a human barrier membrane with galvanic generated electricity
US7486989B2 (en) * 2003-06-30 2009-02-03 Johnson & Johnson Consumer Companies, Inc. Device for delivery of oxidizing agents to barrier membranes
US20040265395A1 (en) * 2003-06-30 2004-12-30 Ying Sun Device for delivery of reducing agents to barrier membranes
US7507228B2 (en) * 2003-06-30 2009-03-24 Johnson & Johnson Consumer Companies, Inc. Device containing a light emitting diode for treatment of barrier membranes
US7480530B2 (en) * 2003-06-30 2009-01-20 Johnson & Johnson Consumer Companies, Inc. Device for treatment of barrier membranes
US7477941B2 (en) * 2003-06-30 2009-01-13 Johnson & Johnson Consumer Companies, Inc. Methods of exfoliating the skin with electricity
US7479133B2 (en) * 2003-06-30 2009-01-20 Johnson & Johnson Consumer Companies, Inc. Methods of treating acne and rosacea with galvanic generated electricity
US7477938B2 (en) * 2003-06-30 2009-01-13 Johnson & Johnson Cosumer Companies, Inc. Device for delivery of active agents to barrier membranes
US7476222B2 (en) * 2003-06-30 2009-01-13 Johnson & Johnson Consumer Companies, Inc. Methods of reducing the appearance of pigmentation with galvanic generated electricity
US8734421B2 (en) 2003-06-30 2014-05-27 Johnson & Johnson Consumer Companies, Inc. Methods of treating pores on the skin with electricity
US7477939B2 (en) * 2003-06-30 2009-01-13 Johnson & Johnson Consumer Companies, Inc. Methods of treating a wound with galvanic generated electricity
US7647100B2 (en) * 2003-07-14 2010-01-12 Power Paper Ltd. Method, apparatus, and kit for onychomycosis treatment
US8455228B2 (en) * 2003-07-16 2013-06-04 University Of South Florida Method to facilitate directed delivery and electroporation using a charged stream
CA2533292C (en) 2003-07-21 2013-12-31 Advancis Pharmaceutical Corporation Antibiotic product, use and formulation thereof
AU2004258949B2 (en) 2003-07-21 2011-02-10 Shionogi, Inc. Antibiotic product, use and formulation thereof
WO2005009364A2 (en) 2003-07-21 2005-02-03 Advancis Pharmaceutical Corporation Antibiotic product, use and formulation thereof
JP2007502296A (en) 2003-08-11 2007-02-08 アドバンシス ファーマスーティカル コーポレイション Robust pellet
EP1653924A4 (en) 2003-08-12 2009-09-09 Middlebrook Pharmaceuticals In Antibiotic product, use and formulation thereof
JP5686494B2 (en) 2003-08-29 2015-03-18 シオノギ インコーポレイテッド Antibiotic preparations, their use and preparation
US8460710B2 (en) 2003-09-15 2013-06-11 Shionogi, Inc. Antibiotic product, use and formulation thereof
US20050096550A1 (en) * 2003-10-31 2005-05-05 Medtronic, Inc. Techniques for transrectal delivery of a denervating agent to the prostate gland
US20050096549A1 (en) * 2003-10-31 2005-05-05 Medtronic, Inc. Techniques for transperineal delivery of a denervating agent to the prostate gland
US8048423B2 (en) * 2003-12-09 2011-11-01 Allergan, Inc. Botulinum toxin therapy for skin disorders
US20050142093A1 (en) * 2003-12-24 2005-06-30 Gregory Skover Treatment of skin with an apparatus and a benefit agent
EP1701705A4 (en) * 2003-12-24 2007-08-08 Advancis Pharmaceutical Corp Enhanced absorption of modified release dosage forms
US8048067B2 (en) * 2003-12-24 2011-11-01 The Regents Of The University Of California Tissue ablation with irreversible electroporation
WO2005084748A1 (en) * 2004-03-04 2005-09-15 Hadasit Medical Research Services & Development Company Ltd. Safe device for iontophoretic delivery of drugs
US8454543B2 (en) * 2004-03-10 2013-06-04 Vision Quest Industries Incorporated Electrodes for orthotic device
US8936560B2 (en) * 2004-03-10 2015-01-20 Vision Quest Industries Incorporated Bracing and electrostimulation for arthritis
US20080234225A1 (en) * 2004-03-15 2008-09-25 John Lezdey Method of treatment
US7559356B2 (en) * 2004-04-19 2009-07-14 Eksident Technologies, Inc. Electrokinetic pump driven heat transfer system
US7521140B2 (en) * 2004-04-19 2009-04-21 Eksigent Technologies, Llc Fuel cell system with electrokinetic pump
EP1765150A2 (en) 2004-05-27 2007-03-28 Ben Beiski Intraoral apparatus and method for blood and saliva monitoring & sensing
US7826726B2 (en) * 2004-06-07 2010-11-02 Mccoy Mark S Intra-convertible thermal vapor extraction and delivery system
WO2006014427A1 (en) 2004-07-02 2006-02-09 Advancis Pharmaceutical Corporation Tablet for pulsed delivery
WO2006003659A2 (en) * 2004-07-06 2006-01-12 Transpharma Medical Ltd. Delivery system for transdermal immunization
TWI259091B (en) * 2004-07-09 2006-08-01 Nat Univ Chung Cheng Electrical energy assisting device for transdermal patch
US7794415B2 (en) * 2004-07-13 2010-09-14 S.C. Johnson & Son, Inc. Surface treatment device
US7857746B2 (en) 2004-10-29 2010-12-28 Nueronetics, Inc. System and method to reduce discomfort using nerve stimulation
US20060095001A1 (en) * 2004-10-29 2006-05-04 Transcutaneous Technologies Inc. Electrode and iontophoresis device
EP1827388A2 (en) * 2004-12-14 2007-09-05 E-Pill Pharma Ltd. Local delivery of drugs or substances using electronic permeability increase
US8349352B2 (en) * 2005-02-04 2013-01-08 Auburn University Therapeutic contact lenses with anti-fungal delivery
US8388995B1 (en) 2006-02-03 2013-03-05 Auburn University Controlled and extended delivery of hyaluronic acid and comfort molecules via a contact lens platform
US9238003B2 (en) 2005-02-04 2016-01-19 Auburn University Extended or continuous wear silicone hydrogel contact lenses for the extended release of comfort molecules
JP2008529606A (en) 2005-02-04 2008-08-07 オーバーン ユニバーシティ Contact drug delivery system
US8157807B2 (en) * 2005-06-02 2012-04-17 The Invention Science Fund I, Llc Skin treatment including patterned light
US20060276859A1 (en) * 2005-06-02 2006-12-07 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Photopatterning of skin
JP4360497B2 (en) * 2005-03-09 2009-11-11 国立大学法人 東京大学 Electric tactile presentation device and electric tactile presentation method
US20060264804A1 (en) * 2005-04-07 2006-11-23 Yoram Karmon Device and kit for delivery of encapsulated substances and methods of use thereof
US20060229524A1 (en) * 2005-04-08 2006-10-12 Alden Ozment Method for the accurate placement of EKG electrodes
US7856263B2 (en) 2005-04-22 2010-12-21 Travanti Pharma Inc. Transdermal systems for the delivery of therapeutic agents including granisetron using iontophoresis
US7300409B2 (en) * 2005-05-12 2007-11-27 S.C. Johnson & Son, Inc. Therapy patch
AU2006248571A1 (en) * 2005-05-19 2006-11-23 E-Pill Pharma, Ltd Ingestible device for nitric oxide production in tissue
US20070106138A1 (en) * 2005-05-26 2007-05-10 Beiski Ben Z Intraoral apparatus for non-invasive blood and saliva monitoring & sensing
US20070032846A1 (en) * 2005-08-05 2007-02-08 Bran Ferren Holographic tattoo
JP2006346368A (en) * 2005-06-20 2006-12-28 Transcutaneous Technologies Inc Iontophoresis apparatus and manufacturing method
US20070045337A1 (en) * 2005-06-24 2007-03-01 Hornsby James R Dispensing device
US20070038270A1 (en) * 2005-07-05 2007-02-15 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Multi step photopatterning of skin
US20070016277A1 (en) * 2005-07-05 2007-01-18 Carol Karat Lip augmentation device
US20070009542A1 (en) * 2005-07-05 2007-01-11 Galit Levin Method and device for transdermal immunization
WO2007010900A1 (en) * 2005-07-15 2007-01-25 Transcu Ltd. Percutaneous absorption patch with application position indicating function, and iontophoresis device
US7824324B2 (en) 2005-07-27 2010-11-02 Neuronetics, Inc. Magnetic core for medical procedures
US7793666B2 (en) * 2005-07-28 2010-09-14 Innovation Biomedical Devices, Inc. Apparatus and method for treatment of infected nail
JP2007037868A (en) * 2005-08-05 2007-02-15 Transcutaneous Technologies Inc Transdermal administration device and its controlling method
US8295922B2 (en) 2005-08-08 2012-10-23 Tti Ellebeau, Inc. Iontophoresis device
US8386030B2 (en) 2005-08-08 2013-02-26 Tti Ellebeau, Inc. Iontophoresis device
US9247802B2 (en) 2005-08-12 2016-02-02 Tcms Transparent Beauty Llc System and method for medical monitoring and treatment through cosmetic monitoring and treatment
US20070060860A1 (en) * 2005-08-18 2007-03-15 Transcutaneous Technologies Inc. Iontophoresis device
WO2007026671A1 (en) * 2005-08-29 2007-03-08 Transcu Ltd. Iontophoresis device for selecting medicine to be administrated according to information from sensor
US20070048340A1 (en) * 2005-08-31 2007-03-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Multi step patterning of a skin surface
WO2007029611A1 (en) * 2005-09-06 2007-03-15 Tti Ellebeau, Inc. Iontophoresis device
CN101252968A (en) 2005-09-15 2008-08-27 Tti优而美株式会社 Rod type iontophoresis device
BRPI0616166A2 (en) * 2005-09-16 2011-06-07 Tti Ellebeau Inc catheter type iontophoresis device
US20070185432A1 (en) * 2005-09-19 2007-08-09 Transport Pharmaceuticals, Inc. Electrokinetic system and method for delivering methotrexate
US20070066934A1 (en) * 2005-09-19 2007-03-22 Transport Pharmaceuticals, Inc. Electrokinetic delivery system and methods therefor
WO2007035941A2 (en) * 2005-09-23 2007-03-29 Alza Corporation Transdermal galantamine delivery system
US20070071807A1 (en) * 2005-09-28 2007-03-29 Hidero Akiyama Capsule-type drug-releasing device and capsule-type drug-releasing device system
WO2007037324A1 (en) * 2005-09-28 2007-04-05 Transcu Ltd. Dry electrode construct for iontophoresis
JP4902543B2 (en) * 2005-09-30 2012-03-21 Tti・エルビュー株式会社 Iontophoresis electrode structure having shape memory separator and iontophoresis device using the same
US20070078445A1 (en) * 2005-09-30 2007-04-05 Curt Malloy Synchronization apparatus and method for iontophoresis device to deliver active agents to biological interfaces
US20070232983A1 (en) * 2005-09-30 2007-10-04 Smith Gregory A Handheld apparatus to deliver active agents to biological interfaces
WO2007037476A1 (en) * 2005-09-30 2007-04-05 Tti Ellebeau, Inc. Iontophoresis apparatus capable of controlling dose and timing of administration of sleep inducer and analeptic agent
KR20080058438A (en) * 2005-09-30 2008-06-25 티티아이 엘뷰 가부시키가이샤 Iontophoresis device to deliver multiple active agents to biological interfaces
US20070197955A1 (en) * 2005-10-12 2007-08-23 Transcutaneous Technologies Inc. Mucous membrane adhesion-type iontophoresis device
EP1957794B1 (en) 2005-11-23 2014-07-02 Eksigent Technologies, LLC Electrokinetic pump designs and drug delivery systems
US8099162B2 (en) 2005-11-29 2012-01-17 Eyegate Pharma, S.A.S. Ocular iontophoresis device
FR2893852B1 (en) * 2005-11-29 2010-09-03 Eyegate Pharma Sa OCULAR IONTOPHORESIS DEVICE
EP1957153A1 (en) * 2005-11-30 2008-08-20 Transoral Pharmaceuticals, Inc. An applicator cartridge for an electrokinetic delivery system for self administration of medicaments
CN101304783A (en) * 2005-11-30 2008-11-12 传导医药制品公司 Combination cartridge and device for electrokinetic delivery of medicament to a treatment site
US8778924B2 (en) 2006-12-04 2014-07-15 Shionogi Inc. Modified release amoxicillin products
US8357394B2 (en) 2005-12-08 2013-01-22 Shionogi Inc. Compositions and methods for improved efficacy of penicillin-type antibiotics
JP4804904B2 (en) * 2005-12-09 2011-11-02 Tti・エルビュー株式会社 Iontophoresis device packaging
US20080033338A1 (en) * 2005-12-28 2008-02-07 Smith Gregory A Electroosmotic pump apparatus and method to deliver active agents to biological interfaces
US20080033398A1 (en) * 2005-12-29 2008-02-07 Transcutaneous Technologies Inc. Device and method for enhancing immune response by electrical stimulation
US8048089B2 (en) 2005-12-30 2011-11-01 Edge Systems Corporation Apparatus and methods for treating the skin
US7848801B2 (en) 2005-12-30 2010-12-07 Tti Ellebeau, Inc. Iontophoretic systems, devices, and methods of delivery of active agents to biological interface
WO2007098058A2 (en) * 2006-02-16 2007-08-30 Biodel, Inc. Device for sublingual drug delivery using iontophoresis
US8036738B2 (en) * 2006-03-14 2011-10-11 New Jersey Institute Of Technology Iontophoretic transdermal drug delivery system based on conductive polyaniline membrane
JP2009530064A (en) * 2006-03-22 2009-08-27 エモーティブ システムズ ピーティーワイ リミテッド Electrode and electrode headset
WO2014151104A1 (en) 2013-03-15 2014-09-25 Edge Systems Llc Devices, systems and methods for treating the skin
US10172644B2 (en) 2006-03-29 2019-01-08 Edge Systems Llc Devices, systems and methods for treating the skin
US9566088B2 (en) 2006-03-29 2017-02-14 Edge Systems Llc Devices, systems and methods for treating the skin
US20080004564A1 (en) * 2006-03-30 2008-01-03 Transcutaneous Technologies Inc. Controlled release membrane and methods of use
WO2008007224A2 (en) 2006-03-31 2008-01-17 Stiefel Research Australia Pty Ltd Foamable suspension gel
FR2899487A1 (en) * 2006-04-10 2007-10-12 Galderma Res & Dev APPLICATION OF ULTRASOUNDS TO NAILS
EP2012706A4 (en) * 2006-04-20 2013-02-13 Transport Pharmaceuticals Inc Pharmaceutical formulations for iontophoretic methotrexate delivery
US20070248629A1 (en) * 2006-04-20 2007-10-25 Friden Phillip M Pharmaceutical formulations for iontophoretic drug delivery
US8299052B2 (en) 2006-05-05 2012-10-30 Shionogi Inc. Pharmaceutical compositions and methods for improved bacterial eradication
US20070276318A1 (en) * 2006-05-26 2007-11-29 Mit, Llp Iontosonic-microneedle applicator apparatus and methods
US20070282246A1 (en) * 2006-06-05 2007-12-06 Mit, Llp Iontosonic-microneedle biosensor apparatus and methods
NZ594136A (en) * 2006-06-15 2013-03-28 Seagull Ip Pty Ltd Delivery of bound material from body to surface using ultrasonic signal
WO2007147043A2 (en) * 2006-06-16 2007-12-21 Transport Pharmaceutical, Inc. Pharmaceutical formulations for iontophoretic tetracycline antibiotic delivery
US20080058701A1 (en) * 2006-07-05 2008-03-06 Transcutaneous Technologies Inc. Delivery device having self-assembling dendritic polymers and method of use thereof
US8184901B2 (en) 2007-02-12 2012-05-22 Tcms Transparent Beauty Llc System and method for applying a reflectance modifying agent to change a person's appearance based on a digital image
US20080077076A1 (en) * 2006-08-29 2008-03-27 Transcutaneous Technologies Inc. Iontophoresis device and method for operation with a usb (universal serial bus) power source
US20100191171A1 (en) * 2006-08-30 2010-07-29 Lg Household & Health Care Ltd. Iontophoresis device
CA2661879A1 (en) * 2006-09-05 2008-03-13 Tti Ellebeau, Inc. Transdermal drug delivery systems, devices, and methods using inductive power supplies
US8609148B2 (en) 2006-10-25 2013-12-17 Revalesio Corporation Methods of therapeutic treatment of eyes
EP2086668B1 (en) 2006-10-25 2016-11-16 Revalesio Corporation Mixing device and method
CA2667614A1 (en) 2006-10-25 2008-09-25 Revalesio Corporation Method of wound care and treatment
US8445546B2 (en) 2006-10-25 2013-05-21 Revalesio Corporation Electrokinetically-altered fluids comprising charge-stabilized gas-containing nanostructures
US8784897B2 (en) 2006-10-25 2014-07-22 Revalesio Corporation Methods of therapeutic treatment of eyes
US8784898B2 (en) 2006-10-25 2014-07-22 Revalesio Corporation Methods of wound care and treatment
US8591957B2 (en) 2006-10-25 2013-11-26 Revalesio Corporation Methods of therapeutic treatment of eyes and other human tissues using an oxygen-enriched solution
US20080193514A1 (en) * 2006-11-02 2008-08-14 Transcu Ltd. Compostions and methods for iontophoresis delivery of active ingredients through hair follicles
WO2008060575A2 (en) 2006-11-13 2008-05-22 Auburn University Drug delivery system and method
US20100076367A1 (en) * 2006-11-24 2010-03-25 Koninklijke Philips Electronics N. V. Iontophoretic device
AU2007329565A1 (en) * 2006-12-01 2008-06-12 Tti Ellebeau, Inc. Systems, devices, and methods for powering and/or controlling devices, for instance transdermal delivery devices
JPWO2008087803A1 (en) * 2007-01-16 2010-05-06 国立大学法人北海道大学 Liposome preparation for iontophoresis encapsulating antioxidant components
US7867592B2 (en) 2007-01-30 2011-01-11 Eksigent Technologies, Inc. Methods, compositions and devices, including electroosmotic pumps, comprising coated porous surfaces
US10486174B2 (en) 2007-02-12 2019-11-26 Tcms Transparent Beauty Llc System and method for applying a reflectance modifying agent electrostatically to improve the visual attractiveness of human skin
US8075482B2 (en) * 2007-02-22 2011-12-13 Ethicon Endo-Surgery, Inc. IRIS valve with control ring
US8070770B2 (en) * 2007-02-22 2011-12-06 Ethicon Endo-Surgery, Inc. Iris valve with novel locking mechanism
WO2008109694A1 (en) * 2007-03-06 2008-09-12 Emotiv Systems Pty Ltd Electrode and electrode headset
US20080261986A1 (en) * 2007-03-30 2008-10-23 Friden Phillip M Pharmaceutical formulations for iontophoretic delivery of an anti-fungal drug
WO2008131072A1 (en) * 2007-04-17 2008-10-30 Transport Pharmaceuticals, Inc. Current density detection and control system and method for an electrokinetic delivery of medicaments
WO2008131205A1 (en) * 2007-04-20 2008-10-30 Transport Pharmaceuticals, Inc. A single use applicator cartridge for an electrokinetic delivery system and method for self administration of medicaments
US10092082B2 (en) 2007-05-29 2018-10-09 Tcms Transparent Beauty Llc Apparatus and method for the precision application of cosmetics
US8197844B2 (en) 2007-06-08 2012-06-12 Activatek, Inc. Active electrode for transdermal medicament administration
JP2010187707A (en) * 2007-06-12 2010-09-02 Hokkaido Univ Liposome preparation for iontophoresis comprising insulin encapsulated therein
US20080312580A1 (en) * 2007-06-15 2008-12-18 Transport Pharmaceuticals, Inc. Current concentration system and method for electrokinetic delivery of medicaments
US20120143178A9 (en) * 2007-06-15 2012-06-07 Primaeva Medical, Inc. Devices and methods for percutaneous energy delivery
US8845630B2 (en) 2007-06-15 2014-09-30 Syneron Medical Ltd Devices and methods for percutaneous energy delivery
EP2162182A1 (en) * 2007-06-15 2010-03-17 Transport Pharmaceuticals, Inc. Method and system for mitigating current concentration in electrokinetic drug delivery
WO2008157683A1 (en) * 2007-06-19 2008-12-24 Transport Pharmaceuticals, Inc. Method and system for treating of onychomycosis with an applicator having a gel medicament layer
CN101820944A (en) * 2007-07-30 2010-09-01 西帖费有限公司 Medical device, in particular for electroporation treatment
EP2200666B1 (en) * 2007-10-09 2014-12-03 Syneron Medical Ltd. Magnetic patch coupling
US9745567B2 (en) 2008-04-28 2017-08-29 Revalesio Corporation Compositions and methods for treating multiple sclerosis
US9523090B2 (en) 2007-10-25 2016-12-20 Revalesio Corporation Compositions and methods for treating inflammation
US10125359B2 (en) 2007-10-25 2018-11-13 Revalesio Corporation Compositions and methods for treating inflammation
WO2009055620A1 (en) * 2007-10-25 2009-04-30 Revalesio Corporation Bacteriostatic or bacteriocidal compositions and methods
KR101304099B1 (en) 2007-12-05 2013-09-05 시네론 메디컬 리미티드 A disposable electromagnetic energy applicator and method of using it
WO2009076134A1 (en) 2007-12-11 2009-06-18 Eksigent Technologies, Llc Electrokinetic pump with fixed stroke volume
KR101836310B1 (en) 2008-01-04 2018-03-08 엣지 시스템즈 엘엘씨 Appratus and method for treating the skin
EP2561819B1 (en) 2008-01-17 2015-01-07 Syneron Medical Ltd. Hair removal apparatus for personal use
US8862223B2 (en) 2008-01-18 2014-10-14 Activatek, Inc. Active transdermal medicament patch and circuit board for same
MX2010007407A (en) 2008-01-24 2010-08-16 Syneron Medical Ltd A device, apparatus, and method of adipose tissue treatment.
WO2009097451A1 (en) 2008-01-29 2009-08-06 Edge Systems Corporation Apparatus and method for treating the skin
BRPI0911757A2 (en) 2008-05-01 2013-09-17 Revalesio Corp compositions and methods for treating digestive disorders.
WO2010011354A2 (en) * 2008-07-25 2010-01-28 Innovation Biomedical Devices, Inc. Enchanced trans-keratin drug delivery
US8150525B2 (en) * 2008-08-27 2012-04-03 Johnson & Johnson Consumer Companies, Inc. Treatment of hyperhydrosis
RU2375955C1 (en) * 2008-09-04 2009-12-20 ООО "Исследовательско-технологический центр "Аусферр" Device for determining acupuncture points parametres
TW201026347A (en) * 2008-09-10 2010-07-16 Transcu Ltd Apparatus and method to dispense HPC-based viscous liquids into porous substrates, e. g., continuous web-based process
BRPI0917921A2 (en) 2008-09-21 2015-11-10 Syneron Medical Ltd method and apparatus for personal skin care
US9675443B2 (en) 2009-09-10 2017-06-13 Johnson & Johnson Vision Care, Inc. Energized ophthalmic lens including stacked integrated components
CA2702604C (en) 2008-09-22 2013-12-03 Biochemics, Inc. Transdermal drug delivery using an osmolyte and vasoactive agent
US20110281834A1 (en) 2008-11-10 2011-11-17 Friden Phillip M Pharmaceutical Formulations for Iontophoretic Delivery of a Corticosteroid
BRPI0921959A2 (en) 2008-12-04 2017-05-30 Biochemics Inc Tattoo Removal Methods and Compositions
US8606366B2 (en) 2009-02-18 2013-12-10 Syneron Medical Ltd. Skin treatment apparatus for personal use and method for using same
KR20120090007A (en) * 2009-02-25 2012-08-16 프리마바 메디컬, 아이엔씨. Devices and methods for percutaneous energy delivery
US20120089232A1 (en) 2009-03-27 2012-04-12 Jennifer Hagyoung Kang Choi Medical devices with galvanic particulates
WO2010118153A1 (en) * 2009-04-07 2010-10-14 Nitric Biotherapeutics, Inc. Controlling drug transport and current in iontophoretic onychomycosis treatment
US8815292B2 (en) 2009-04-27 2014-08-26 Revalesio Corporation Compositions and methods for treating insulin resistance and diabetes mellitus
US8414559B2 (en) 2009-05-07 2013-04-09 Rainbow Medical Ltd. Gastroretentive duodenal pill
US20100286587A1 (en) * 2009-05-07 2010-11-11 Yossi Gross Sublingual electrical drug delivery
US10206813B2 (en) 2009-05-18 2019-02-19 Dose Medical Corporation Implants with controlled drug delivery features and methods of using same
WO2010144424A2 (en) * 2009-06-09 2010-12-16 Tti Ellebeau, Inc. Long life high capacity electrode, device, and method of manufacture
US20100331812A1 (en) * 2009-06-29 2010-12-30 Nitric Biotherapeutics, Inc. Pharmaceutical Formulations for Iontophoretic Delivery of an Immunomodulator
EP2451367B1 (en) 2009-07-08 2020-01-22 Edge Systems Corporation Devices for treating the skin using time-release substances
US9415203B2 (en) * 2009-08-28 2016-08-16 Caci Microlift Limited Electrostimulation devices
US9937343B2 (en) 2009-08-28 2018-04-10 Caci Microlift Limited Electrostimulation skin massage devices
US9017310B2 (en) * 2009-10-08 2015-04-28 Palo Alto Research Center Incorporated Transmucosal drug delivery device and method including microneedles
US8882748B2 (en) * 2009-10-08 2014-11-11 Palo Alto Research Center Incorporated Transmucosal drug delivery device and method including chemical permeation enhancers
US9014799B2 (en) * 2009-10-08 2015-04-21 Palo Alto Research Center Incorporated Transmucosal drug delivery device and method including electrically-actuated permeation enhancement
ES2617760T3 (en) * 2009-11-13 2017-06-19 Johnson & Johnson Consumer Inc. Galvanic device for skin treatment
JP5463136B2 (en) * 2009-12-22 2014-04-09 帝國製薬株式会社 Electrode device used for iontophoresis therapy
EP2520101B1 (en) 2009-12-31 2021-03-17 ZetrOZ Systems LLC Low-profile ultrasound transducer
SG184128A1 (en) * 2010-03-17 2012-10-30 Nanomed Devices Inc A built-in non-verbal instructional device integratable to applicators
CN101837163B (en) * 2010-04-12 2013-04-10 上海现代药物制剂工程研究中心有限公司 Heparin rectum iontophoretic drug delivery system
US9237961B2 (en) * 2010-04-23 2016-01-19 Medtronic Vascular, Inc. Stent delivery system for detecting wall apposition of the stent during deployment
EP2566460A4 (en) 2010-05-07 2015-12-23 Revalesio Corp Compositions and methods for enhancing physiological performance and recovery time
WO2012021856A1 (en) 2010-08-12 2012-02-16 Revalesio Corporation Compositions and methods for treatment of taupathy
TWI394587B (en) * 2011-01-07 2013-05-01 Iner Aec Executive Yuan A radiolabeled nucleoside analogue, a method for preparing the same and the use thereof
AU2011200394B2 (en) * 2011-01-31 2015-01-22 Palo Alto Research Center Incorporated Transmucosal drug delivery device and method including electrically-actuated permeation enhancement
US8950862B2 (en) 2011-02-28 2015-02-10 Johnson & Johnson Vision Care, Inc. Methods and apparatus for an ophthalmic lens with functional insert layers
US8970559B1 (en) * 2011-03-08 2015-03-03 Henry Lansing McVickar Fingernail stylus
US9110310B2 (en) 2011-03-18 2015-08-18 Johnson & Johnson Vision Care, Inc. Multiple energization elements in stacked integrated component devices
US9233513B2 (en) 2011-03-18 2016-01-12 Johnson & Johnson Vision Care, Inc. Apparatus for manufacturing stacked integrated component media inserts for ophthalmic devices
US9698129B2 (en) 2011-03-18 2017-07-04 Johnson & Johnson Vision Care, Inc. Stacked integrated component devices with energization
US10451897B2 (en) 2011-03-18 2019-10-22 Johnson & Johnson Vision Care, Inc. Components with multiple energization elements for biomedical devices
US9804418B2 (en) * 2011-03-21 2017-10-31 Johnson & Johnson Vision Care, Inc. Methods and apparatus for functional insert with power layer
EP2704759A4 (en) 2011-05-05 2015-06-03 Eksigent Technologies Llc Gel coupling for electrokinetic delivery systems
US10245178B1 (en) 2011-06-07 2019-04-02 Glaukos Corporation Anterior chamber drug-eluting ocular implant
US10004526B2 (en) * 2011-07-25 2018-06-26 Covidien Lp Ultrasonic dissection system
EP2736588A4 (en) 2011-07-27 2015-06-10 Vision Quest Ind Inc Dba Vq Orthocare Electrostimulation system
WO2013033782A1 (en) * 2011-09-09 2013-03-14 International Scientific Pty Ltd Method and device for transdermal delivery of substances
US8857983B2 (en) 2012-01-26 2014-10-14 Johnson & Johnson Vision Care, Inc. Ophthalmic lens assembly having an integrated antenna structure
US9980810B2 (en) * 2012-04-03 2018-05-29 Johnson & Johnson Vision Care, Inc. System controller for variable-optic electronic ophthalmic lens
US9351827B2 (en) * 2012-04-03 2016-05-31 Johnson & Johnson Vision Care, Inc. Lens driver for variable-optic electronic ophthalmic lens
RU2495628C1 (en) * 2012-04-18 2013-10-20 Государственное бюджетное учреждение здравоохранения Московской области "Московский областной научно-исследовательский клинический институт им. М.Ф. Владимирского" (ГБУЗ МО МОНИКИ им. М.Ф. Владимирского) Method of selecting tactics of treating actinic keratosis
WO2013190537A1 (en) * 2012-06-18 2013-12-27 Michael Tavger Method and system for delivering solution into the pores of recipient human skin
US9271783B2 (en) 2012-07-17 2016-03-01 Covidien Lp End-effector assembly including a pressure-sensitive layer disposed on an electrode
US20140088372A1 (en) * 2012-09-25 2014-03-27 Google Inc. Information processing method
US9005108B2 (en) 2012-09-27 2015-04-14 Palo Alto Research Center Incorporated Multiple reservoir drug delivery device and methods
US9999720B2 (en) 2012-09-27 2018-06-19 Palo Alto Research Center Incorporated Drug reconstitution and delivery device and methods
US9872812B2 (en) 2012-09-28 2018-01-23 Kpr U.S., Llc Residual pressure control in a compression device
US9744341B2 (en) 2013-01-15 2017-08-29 Palo Alto Research Center Incorporated Devices and methods for intraluminal retention and drug delivery
US9050053B2 (en) 2013-02-15 2015-06-09 Naimco, Inc. Ultrasound device with cavity for conductive medium
US20140257064A1 (en) * 2013-03-11 2014-09-11 Birchwood Laboratories, Inc. Sweat analyte testing components and methods
US10238812B2 (en) 2013-03-15 2019-03-26 Edge Systems Llc Skin treatment systems and methods using needles
US9592151B2 (en) 2013-03-15 2017-03-14 Glaukos Corporation Systems and methods for delivering an ocular implant to the suprachoroidal space within an eye
WO2014183764A1 (en) * 2013-05-15 2014-11-20 Stefan Margraf Skin applicator for applying highly volatile substances
US9320645B2 (en) * 2013-05-29 2016-04-26 Terry Glasser Approach to administering ocular medication
EP3441109A1 (en) 2013-05-30 2019-02-13 Graham H. Creasey Flexible dermal patch for a topical nerve stimulator system
US10010704B2 (en) 2013-08-23 2018-07-03 Elwha Llc Systems, methods, and devices for delivering treatment to a skin surface
US9811641B2 (en) 2013-08-23 2017-11-07 Elwha Llc Modifying a cosmetic product based on a microbe profile
US9526480B2 (en) 2013-11-27 2016-12-27 Elwha Llc Devices and methods for profiling microbiota of skin
WO2015027055A1 (en) * 2013-08-23 2015-02-26 Elwha Llc Systems, methods, and devices for delivering treatment to a skin surface
US9805171B2 (en) 2013-08-23 2017-10-31 Elwha Llc Modifying a cosmetic product based on a microbe profile
US9456777B2 (en) 2013-08-23 2016-10-04 Elwha Llc Systems, methods, and devices for assessing microbiota of skin
US9549703B2 (en) 2013-11-27 2017-01-24 Elwha Llc Devices and methods for sampling and profiling microbiota of skin
US10152529B2 (en) 2013-08-23 2018-12-11 Elwha Llc Systems and methods for generating a treatment map
US9557331B2 (en) 2013-08-23 2017-01-31 Elwha Llc Systems, methods, and devices for assessing microbiota of skin
US9390312B2 (en) 2013-08-23 2016-07-12 Elwha Llc Systems, methods, and devices for assessing microbiota of skin
US20150342661A1 (en) * 2013-10-09 2015-12-03 Venus Concept Ltd Integrated Treatment System
CN113384373B (en) * 2013-11-05 2022-10-21 辛纳吉勒公司 Device and method for continuous drug delivery via the oral cavity
US9186278B2 (en) 2013-11-27 2015-11-17 Elwha Llc Systems and devices for sampling and profiling microbiota of skin
US9610037B2 (en) 2013-11-27 2017-04-04 Elwha Llc Systems and devices for profiling microbiota of skin
US9526450B2 (en) 2013-11-27 2016-12-27 Elwha Llc Devices and methods for profiling microbiota of skin
US9297083B2 (en) 2013-12-16 2016-03-29 Palo Alto Research Center Incorporated Electrolytic gas generating devices, actuators, and methods
US20150265825A1 (en) 2014-03-21 2015-09-24 L'oreal Combined sonic and iontophoretic skin care device
CA2950187A1 (en) 2014-05-29 2015-12-03 Glaukos Corporation Implants with controlled drug delivery features and methods of using same
JP6444069B2 (en) * 2014-06-17 2018-12-26 マクセルホールディングス株式会社 Skin care equipment
US10278675B2 (en) 2014-07-31 2019-05-07 Palo Alto Research Center Incorporated Implantable estrus detection devices, systems, and methods
US9801660B2 (en) 2014-07-31 2017-10-31 Palo Alto Research Center Incorporated Implantable fluid delivery devices, systems, and methods
US9383593B2 (en) 2014-08-21 2016-07-05 Johnson & Johnson Vision Care, Inc. Methods to form biocompatible energization elements for biomedical devices comprising laminates and placed separators
US10361405B2 (en) 2014-08-21 2019-07-23 Johnson & Johnson Vision Care, Inc. Biomedical energization elements with polymer electrolytes
US9715130B2 (en) 2014-08-21 2017-07-25 Johnson & Johnson Vision Care, Inc. Methods and apparatus to form separators for biocompatible energization elements for biomedical devices
US9941547B2 (en) 2014-08-21 2018-04-10 Johnson & Johnson Vision Care, Inc. Biomedical energization elements with polymer electrolytes and cavity structures
US10361404B2 (en) 2014-08-21 2019-07-23 Johnson & Johnson Vision Care, Inc. Anodes for use in biocompatible energization elements
US9599842B2 (en) 2014-08-21 2017-03-21 Johnson & Johnson Vision Care, Inc. Device and methods for sealing and encapsulation for biocompatible energization elements
US10381687B2 (en) 2014-08-21 2019-08-13 Johnson & Johnson Vision Care, Inc. Methods of forming biocompatible rechargable energization elements for biomedical devices
US10627651B2 (en) 2014-08-21 2020-04-21 Johnson & Johnson Vision Care, Inc. Methods and apparatus to form biocompatible energization primary elements for biomedical devices with electroless sealing layers
US9793536B2 (en) 2014-08-21 2017-10-17 Johnson & Johnson Vision Care, Inc. Pellet form cathode for use in a biocompatible battery
CA2965187A1 (en) 2014-10-21 2016-04-28 Hexima Limited Plant defensin for treating fungal infections
US10179229B2 (en) 2014-12-23 2019-01-15 Edge Systems Llc Devices and methods for treating the skin using a porous member
EP3795204B1 (en) 2014-12-23 2023-10-25 HydraFacial LLC Device for treating the skin using a rollerball
US9861818B2 (en) * 2014-12-31 2018-01-09 Ziip, Llc Method and device for electrical current treatment
EP3291872A4 (en) 2015-05-06 2019-02-13 SynAgile Corporation Pharmaceutical suspensions containing drug particles, devices for their administration, and methods of their use
US11241357B2 (en) 2015-07-08 2022-02-08 Edge Systems Llc Devices, systems and methods for promoting hair growth
US10130578B2 (en) * 2015-07-23 2018-11-20 Johnson & Johnson Consumer Inc. Topical delivery of skin compositions having low pH
US11564833B2 (en) 2015-09-25 2023-01-31 Glaukos Corporation Punctal implants with controlled drug delivery features and methods of using same
WO2017080620A1 (en) * 2015-11-13 2017-05-18 Sca Hygiene Products Ab Wearable absorbent hygiene article comprising an electronics unit
JP6685395B2 (en) * 2015-11-13 2020-04-22 エシティ・ハイジーン・アンド・ヘルス・アクチエボラグ Wearable absorbent hygiene article with magnetic switch
US10345620B2 (en) 2016-02-18 2019-07-09 Johnson & Johnson Vision Care, Inc. Methods and apparatus to form biocompatible energization elements incorporating fuel cells for biomedical devices
WO2017168174A1 (en) 2016-04-02 2017-10-05 N4 Pharma Uk Limited New pharmaceutical forms of sildenafil
US11318043B2 (en) 2016-04-20 2022-05-03 Dose Medical Corporation Bioresorbable ocular drug delivery device
AU2017306078B2 (en) * 2016-08-01 2023-03-09 Drexel University Devices and methods for treatment of skin conditions
JP2018042886A (en) * 2016-09-16 2018-03-22 ロレアル Portable iontophoresis device
EP3597103B1 (en) * 2017-03-16 2022-05-04 Fukuda Denshi Co., Ltd. Bioelectrode sheet
US10406358B1 (en) * 2017-04-24 2019-09-10 Todd M. Bertoch Chronic pain treatment device
US20200061357A1 (en) * 2017-05-02 2020-02-27 Georgia Tech Research Corporation Targeted drug delivery methods using a microneedle
DE102017123809A1 (en) * 2017-10-12 2019-04-18 Swiss Spa System Ltd. In one hand durable device for electrically assisted skin treatment, additional part for this device and blister for this additional part
US11806163B2 (en) 2018-10-09 2023-11-07 Inter.mix, Inc. Hydration testing article
RU2709159C1 (en) * 2018-10-26 2019-12-16 Федеральное государственное бюджетное образовательное учреждение высшего образования "Владимирский Государственный Университет имени Александра Григорьевича и Николая Григорьевича Столетовых" (ВлГУ) Device for treating fungal infections of nails
CN116271113B (en) * 2023-05-24 2023-08-08 四川大学华西医院 Multifunctional photo-curing sound guide gel and preparation method and application thereof
CN117462836A (en) * 2023-12-26 2024-01-30 山东百多安医疗器械股份有限公司 Functionalized ultrasonic controlled-release puncture dressing patch and preparation method thereof

Family Cites Families (187)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US600290A (en) 1898-03-08 Therapeutic electrode
US206474A (en) 1878-07-30 Improvement in glove-electrodes
US484522A (en) 1892-10-18 Edward h
US279524A (en) 1883-06-19 Thimble
DE603705C (en) 1931-06-18 1934-10-08 Desider Deutsch Dr Electrode for introducing medicines into the body by means of iontophoresis
US2126070A (en) 1932-04-29 1938-08-09 Wappler Frederick Charles Electrotherapy
US2047308A (en) 1934-05-05 1936-07-14 T M Chapman S Sons Co Electrical therapeutic pad
US2123980A (en) 1934-07-21 1938-07-19 G M Basford Company Therapeutic treatment
US2834344A (en) 1954-07-22 1958-05-13 Lion Brush K K Device for penetrating teeth with fluoride
US3107672A (en) 1958-05-27 1963-10-22 Ewald Rose Electrical apparatus for cosmetic treatment of the skin
US3019787A (en) 1960-10-05 1962-02-06 Joe J Simmons Apparatus for electrolytic dental desensitization
US3048170A (en) 1960-11-08 1962-08-07 Lemos Albano Electrical devices for the application of fluid to the gums
US3163166A (en) 1961-04-28 1964-12-29 Colgate Palmolive Co Iontophoresis apparatus
US3298368A (en) 1964-04-24 1967-01-17 Charos Peter Heated cream applicator gloves
FR1445703A (en) 1965-06-03 1966-07-15 Advanced ionization apparatus
US3520297A (en) 1967-01-31 1970-07-14 Chemway Corp Iontophoretic toothbrush
US3556105A (en) 1968-05-24 1971-01-19 Lillian B Shepard Electrical stimulator and mitten
US3645260A (en) 1970-07-17 1972-02-29 Health Systems Inc Dental desensitizer
US3716054A (en) 1970-08-11 1973-02-13 W Porter Apparatus for applying medication to teeth and body tissue
US3848600A (en) 1972-02-03 1974-11-19 Ndm Corp Indifferent electrode in electrosurgical procedures and method of use
US3831598A (en) 1972-09-28 1974-08-27 I Tice Sterile anesthetic instruments
US4116238A (en) 1976-08-18 1978-09-26 Midgard Electronics Company, Inc. High voltage constant current source for iontophoresis
US4211222A (en) 1976-08-25 1980-07-08 Robert Tapper Iontophoretic burn-protection method
SU654254A2 (en) 1977-02-07 1979-03-30 В. Н. Серов Device for treating eyes
US4325367A (en) 1977-06-13 1982-04-20 Robert Tapper Iontophoretic treatment apparatus
US4301794A (en) 1978-10-18 1981-11-24 Robert Tapper Method for iontophoretic treatment
US4838273A (en) 1979-04-30 1989-06-13 Baxter International Inc. Medical electrode
US4292968A (en) 1979-11-26 1981-10-06 Sybron Corporation Electric supply for ion therapy
SU931191A1 (en) 1980-01-18 1982-05-30 Предприятие П/Я А-3852 Device for treating middle and internal ear
SU1003853A1 (en) 1980-03-17 1983-03-15 Белорусский Научно-Исследовательский Институт Неврологии,Нейрохирургии И Физиотерапии Device for electrophonoresis
US4383529A (en) 1980-11-03 1983-05-17 Wescor, Inc. Iontophoretic electrode device, method and gel insert
US4416274A (en) 1981-02-23 1983-11-22 Motion Control, Inc. Ion mobility limiting iontophoretic bioelectrode
US4406658A (en) 1981-03-06 1983-09-27 Medtronic, Inc. Iontophoretic device with reversible polarity
US4820263A (en) 1981-03-06 1989-04-11 Medtronic, Inc. Apparatus and method for iontophoretic drug delivery
JPS5810066A (en) 1981-07-10 1983-01-20 株式会社アドバンス Plaster structure for ion tofuorese
FR2513129A1 (en) 1981-09-24 1983-03-25 Moreau Lavaud Reine Portable skin cosmetic treatment device - has current generator circuit breaker and holder for interchangeable electrodes incorporated into body
US4393884A (en) 1981-09-25 1983-07-19 Jacobs Allen W Demand inhaler for oral administration of tobacco, tobacco-like, or other substances
US4429703A (en) 1982-02-22 1984-02-07 William Haber Cigarette substitute
US4510939A (en) 1982-12-22 1985-04-16 Biosonics, Inc. Means for transferring electrical energy to and from living tissue
US4639244A (en) 1983-05-03 1987-01-27 Nabil I. Rizk Implantable electrophoretic pump for ionic drugs and associated methods
US4808152A (en) 1983-08-18 1989-02-28 Drug Delivery Systems Inc. System and method for controlling rate of electrokinetic delivery of a drug
US4919648A (en) 1983-08-18 1990-04-24 Drug Delivery Systems Inc. High tack drug patch
US5865786A (en) 1983-08-18 1999-02-02 Drug Delivery Systems, Inc. Programmable control and mounting system for transdermal drug applicator
US4708716A (en) 1983-08-18 1987-11-24 Drug Delivery Systems Inc. Transdermal drug applicator
US5135479A (en) 1983-08-18 1992-08-04 Drug Delivery Systems, Inc. Programmable control and mounting system for transdermal drug applicator
CA1262564A (en) 1983-09-01 1989-10-31 Minoru Sasaki Iontophoresis device
US4813437A (en) 1984-01-09 1989-03-21 Ray J Philip Nicotine dispensing device and method for the manufacture thereof
US4655229A (en) 1984-01-30 1987-04-07 R. J. Reynolds Tobacco Company Flavor delivery system
US4665921A (en) 1984-05-28 1987-05-19 Teranishi Electric Works, Ltd. High potential generating toothbrush
US5135477A (en) 1984-10-29 1992-08-04 Medtronic, Inc. Iontophoretic drug delivery
US4747819A (en) 1984-10-29 1988-05-31 Medtronic, Inc. Iontophoretic drug delivery
SE8405479D0 (en) 1984-11-01 1984-11-01 Nilsson Sven Erik WANT TO ADMINISTER VOCABULARY, PHYSIOLOGY, ACTIVE SUBJECTS AND DEVICE FOR THIS
US4702732A (en) 1984-12-24 1987-10-27 Trustees Of Boston University Electrodes, electrode assemblies, methods, and systems for tissue stimulation and transdermal delivery of pharmacologically active ligands
US4800903A (en) 1985-05-24 1989-01-31 Ray Jon P Nicotine dispenser with polymeric reservoir of nicotine
JPS6222662A (en) 1985-07-19 1987-01-30 林原 健 Ion introducing electronic treatment device
AT385664B (en) 1985-07-31 1988-05-10 Hepax Ltd ELECTROMEDICAL THERAPY DEVICE
US4756318A (en) 1985-10-28 1988-07-12 R. J. Reynolds Tobacco Company Smoking article with tobacco jacket
US4793366A (en) 1985-11-12 1988-12-27 Hill Ira D Nicotine dispensing device and methods of making the same
US4763660A (en) 1985-12-10 1988-08-16 Cherne Industries, Inc. Flexible and disposable electrode belt device
JPS62139672A (en) 1985-12-14 1987-06-23 林原 健 Remedy device for positive and negative iontophoresis
US4767402A (en) 1986-07-08 1988-08-30 Massachusetts Institute Of Technology Ultrasound enhancement of transdermal drug delivery
US5042975A (en) 1986-07-25 1991-08-27 Rutgers, The State University Of New Jersey Iontotherapeutic device and process and iontotherapeutic unit dose
US5961482A (en) 1986-07-25 1999-10-05 Rutgers, The State University Of New Jersey Iontotherapeutic device and process and iontotherapeutic unit dose
US5250022A (en) 1990-09-25 1993-10-05 Rutgers, The State University Of New Jersey Iontotherapeutic devices, reservoir electrode devices therefore, process and unit dose
US4735217A (en) 1986-08-21 1988-04-05 The Procter & Gamble Company Dosing device to provide vaporized medicament to the lungs as a fine aerosol
JPS63135179A (en) 1986-11-26 1988-06-07 立花 俊郎 Subcataneous drug administration set
US4771796A (en) 1987-01-07 1988-09-20 Fritz Myer Electrically operated simulated cigarette
US4931046A (en) 1987-05-15 1990-06-05 Newman Martin H Iontophoresis drug delivery system
US4787888A (en) 1987-06-01 1988-11-29 University Of Connecticut Disposable piezoelectric polymer bandage for percutaneous delivery of drugs and method for such percutaneous delivery (a)
US4865582A (en) 1987-06-05 1989-09-12 Drug Delivery Systems Inc. Disposable transdermal drug applicators
FR2619308B1 (en) 1987-08-12 1993-12-17 Oreal MASSAGE APPARATUS
JPS6456060A (en) 1987-08-27 1989-03-02 Hayashibara Takeshi Low frequency medical treatment device
US4942883A (en) 1987-09-29 1990-07-24 Newman Martin H Drug delivery device
WO1989006555A1 (en) 1988-01-21 1989-07-27 Massachusetts Institute Of Technology Transport of molecules across tissue using electroporation
US5362307A (en) 1989-01-24 1994-11-08 The Regents Of The University Of California Method for the iontophoretic non-invasive-determination of the in vivo concentration level of an inorganic or organic substance
WO1989006989A1 (en) 1988-01-29 1989-08-10 The Regents Of The University Of California Iontophoretic non-invasive sampling or delivery device
US4957480A (en) 1988-02-02 1990-09-18 Universal Health Products, Inc. Method of facial toning
IL86076A (en) 1988-04-14 1992-12-01 Inventor S Funding Corp Ltd Transdermal drug delivery device
US4997418A (en) 1988-04-21 1991-03-05 C. P. Chambers Epidermal iontophoresis device
US5162042A (en) 1988-07-05 1992-11-10 Alza Corporation Electrotransport transdermal system
IL87004A (en) * 1988-07-06 1992-08-18 Technion Res & Dev Foundation Method and apparatus for bioaffinity separation
US4922901A (en) 1988-09-08 1990-05-08 R. J. Reynolds Tobacco Company Drug delivery articles utilizing electrical energy
CA2001444C (en) 1988-10-28 2000-07-25 Darrel F. Untereker Iontophoresis electrode
US5501705A (en) 1988-10-31 1996-03-26 Fakhri; Omar Method for the treatment of psoriasis with electric current
US5006108A (en) 1988-11-16 1991-04-09 Noven Pharmaceuticals, Inc. Apparatus for iontophoretic drug delivery
US4917119A (en) 1988-11-30 1990-04-17 R. J. Reynolds Tobacco Company Drug delivery article
US5135478A (en) 1989-05-10 1992-08-04 Drug Delivery Systems Inc. Multi-signal electrical transdermal drug applicator
US4979938A (en) 1989-05-11 1990-12-25 Iomed, Inc. Method of iontophoretically treating acne, furuncles and like skin disorders
US5374241A (en) 1989-07-21 1994-12-20 Iomed, Inc. Electrodes for iontophoresis
US4950229A (en) 1989-09-25 1990-08-21 Becton, Dickinson And Company Apparatus for an electrode used for iontophoresis
US5060671A (en) 1989-12-01 1991-10-29 Philip Morris Incorporated Flavor generating article
US5047007A (en) 1989-12-22 1991-09-10 Medtronic, Inc. Method and apparatus for pulsed iontophoretic drug delivery
US5115805A (en) 1990-02-23 1992-05-26 Cygnus Therapeutic Systems Ultrasound-enhanced delivery of materials into and through the skin
JP2816886B2 (en) 1990-03-05 1998-10-27 興和株式会社 Bioelectric device
US6004309A (en) 1990-03-30 1999-12-21 Alza Corporation Method and apparatus for controlled environment electrotransport
ATE251929T1 (en) 1990-03-30 2003-11-15 Alza Corp IONTOPHORETIC ADMINISTRATION DEVICE
US5133352A (en) 1990-04-12 1992-07-28 Kent, Lathrop And Johnston Method for treating herpes simplex
US5167242A (en) 1990-06-08 1992-12-01 Kabi Pharmacia Aktiebolaq Nicotine-impermeable container and method of fabricating the same
US5147291A (en) 1990-06-11 1992-09-15 Cukier A David Sound transmission apparatus for uniformly administering chemical composition through the skin
US5037381A (en) 1990-07-27 1991-08-06 Bock C Randolph Electrically assisted transdermal transport device and method for renewing the device
US5160316A (en) 1990-09-10 1992-11-03 Henley Julian L Iontophoretic drug delivery apparatus
US5362308A (en) 1990-09-25 1994-11-08 Rutgers, The State University Of New Jersey Disposable dosage unit for iontophoresis-facilitated transdermal delivery, related devices and processes
DE4114677A1 (en) 1990-10-10 1992-02-27 Mario Bergner APPLICATION ARRANGEMENT OF DIFFERENT ELECTRICALLY CONNECTED METALS ON THE HUMAN BODY TO A BIOELECTRIC SYSTEM IN THE MEANING OF THE ELECTROCHEMICAL VOLTAGE RANGE WITH VOLTAGE INCREASING WITH POSSIBLE USE OF COMMERCIAL ECG FLASHER ELEMENTS
US6238381B1 (en) * 1990-11-01 2001-05-29 Robert Tapper Iontophoretic treatment system
US5254081A (en) 1991-02-01 1993-10-19 Empi, Inc. Multiple site drug iontophoresis electronic device and method
NL9100662A (en) 1991-04-17 1992-11-16 Optische Ind De Oude Delft Nv DEVICE FOR PERFORMING AN ITHOPHORESIS TREATMENT ON A PATIENT.
DE4120517A1 (en) 1991-06-18 1992-12-24 Kleditsch Bernhard Dr Med Dent DC GENERATOR FOR THE TREATMENT OF THE INITIAL STAGE HERPES LABIALIS AND OTHER INITIAL INFLAMMATION OF THE HAUTAREAL
GB2257632B (en) 1991-07-17 1995-03-22 Innovative Medical Devices Skin treatment device
US5203768A (en) 1991-07-24 1993-04-20 Alza Corporation Transdermal delivery device
US5464387A (en) 1991-07-24 1995-11-07 Alza Corporation Transdermal delivery device
US5169384A (en) 1991-08-16 1992-12-08 Bosniak Stephen L Apparatus for facilitating post-traumatic, post-surgical, and/or post-inflammatory healing of tissue
US5171215A (en) 1991-08-22 1992-12-15 Flanagan Dennis F Endermic method and apparatus
ATE143279T1 (en) 1991-12-03 1996-10-15 Alza Corp IONTOPHORETIC DISTRIBUTION DEVICE AND SUPPLY NETWORK THEREOF
CA2087087C (en) 1992-01-22 2000-07-18 Burton H. Sage, Jr. Molecules for iontophoretic delivery
US5360440A (en) 1992-03-09 1994-11-01 Boston Scientific Corporation In situ apparatus for generating an electrical current in a biological environment
US5589563A (en) 1992-04-24 1996-12-31 The Polymer Technology Group Surface-modifying endgroups for biomedical polymers
US5310404A (en) 1992-06-01 1994-05-10 Alza Corporation Iontophoretic delivery device and method of hydrating same
CA2183875C (en) 1992-06-02 2003-10-14 Robert M. Myers Electrotransport drug delivery device
US5312326A (en) 1992-06-02 1994-05-17 Alza Corporation Iontophoretic drug delivery apparatus
US5607691A (en) 1992-06-12 1997-03-04 Affymax Technologies N.V. Compositions and methods for enhanced drug delivery
US5331979A (en) 1992-07-27 1994-07-26 Henley Julian L Iontophoretic cigarette substitute
US5688233A (en) 1992-08-17 1997-11-18 Genetronics, Inc. Electronincorporation enhanced transdermal delivery of molecules
US5421816A (en) 1992-10-14 1995-06-06 Endodermic Medical Technologies Company Ultrasonic transdermal drug delivery system
US5322520A (en) 1992-11-12 1994-06-21 Implemed, Inc. Iontophoretic structure for medical devices
US5298017A (en) 1992-12-29 1994-03-29 Alza Corporation Layered electrotransport drug delivery system
EP0776677B1 (en) 1992-12-31 2000-03-08 Alza Corporation Electrotransport system
US5443441A (en) 1993-03-05 1995-08-22 De Claviere; Anne Marie Apparatus and method for transdermal delivery of cosmetic compositions
US6004547A (en) 1997-09-29 1999-12-21 Focal, Inc. Apparatus and method for local application of polymeric material to tissue
US5667487A (en) 1993-04-07 1997-09-16 Henley; Julian L. Ionosonic drug delivery apparatus
US5458569A (en) 1993-06-08 1995-10-17 Becton Dickinson And Company Wearable iontophoresis system
FR2709670B1 (en) 1993-09-10 1995-10-20 Asulab Sa Device in three modules for transdermal administration of drugs by electrophoresis or iontophoresis.
US5415629A (en) 1993-09-15 1995-05-16 Henley; Julian L. Programmable apparatus for the transdermal delivery of drugs and method
US5540669A (en) 1993-09-30 1996-07-30 Becton, Dickinson And Company Iontophoretic drug delivery system and method for using same
CA2172991A1 (en) 1993-09-30 1995-04-06 Burton H. Sage, Jr. Iontophoretic drug delivery system and method
US5458140A (en) 1993-11-15 1995-10-17 Non-Invasive Monitoring Company (Nimco) Enhancement of transdermal monitoring applications with ultrasound and chemical enhancers
US5441936A (en) 1993-12-07 1995-08-15 Houghten Pharmaceuticals, Inc. Antiviral peptides
US5554361A (en) 1994-01-21 1996-09-10 Dixon; Gary W. Processed product for skin and hair treatment
WO1995035132A1 (en) 1994-06-17 1995-12-28 Hisamitsu Pharmaceutical Co., Inc. Electrode for iontophoresis and device using the same
US6048545A (en) 1994-06-24 2000-04-11 Biozone Laboratories, Inc. Liposomal delivery by iontophoresis
JP4090072B2 (en) 1994-07-13 2008-05-28 アルザ・コーポレーション Compositions and methods for facilitating transdermal electrotransport agent administration
US5795321A (en) 1994-09-30 1998-08-18 Becton Dickinson And Company Iontophoretic drug delivery system, including removable controller
US5514167A (en) 1994-10-24 1996-05-07 Mgb Technologies Corporation Hand holdable human skin treatment apparatus
US5551953A (en) 1994-10-31 1996-09-03 Alza Corporation Electrotransport system with remote telemetry link
US5736580A (en) 1994-11-14 1998-04-07 Alza Croporation Composition, device, and method for electrotransport agent delivery
FR2726770B1 (en) 1994-11-16 1997-01-31 Lhd Lab Hygiene Dietetique TRANSDERMAL DRUG DELIVERY DEVICE FOR THE TREATMENT OF MALE ERECTILE IMPOTENCE
JP3170172B2 (en) 1995-03-30 2001-05-28 ティーディーケイ株式会社 Chip component supply device and chip component supply case used for the device
US5697896A (en) 1994-12-08 1997-12-16 Alza Corporation Electrotransport delivery device
US5562607A (en) 1995-01-18 1996-10-08 Alza Corporation Electrotransport device having reusable controller power saver
BR9506937A (en) 1995-01-27 1997-09-09 Aloisi Alessandro Iontophoresis physiotherapy device with frozen medicine crystals
US6032073A (en) 1995-04-07 2000-02-29 Novartis Ag Iontophoretic transdermal system for the administration of at least two substances
US5882676A (en) 1995-05-26 1999-03-16 Alza Corporation Skin permeation enhancer compositions using acyl lactylates
US6041252A (en) 1995-06-07 2000-03-21 Ichor Medical Systems Inc. Drug delivery system and method
US5983130A (en) 1995-06-07 1999-11-09 Alza Corporation Electrotransport agent delivery method and apparatus
US5788666A (en) 1995-06-15 1998-08-04 Empi, Inc. Iontophoresis electrode
US6041253A (en) 1995-12-18 2000-03-21 Massachusetts Institute Of Technology Effect of electric field and ultrasound for transdermal drug delivery
US5674546A (en) * 1995-08-10 1997-10-07 Nabisco Technology Company Package for storing and cooking an omelet
AU720742B2 (en) 1995-09-28 2000-06-08 Vyteris, Inc. Iontophoretic drug delivery system, including disposable patch
WO1997014473A1 (en) 1995-10-18 1997-04-24 Novartis Ag Thermopile powered transdermal drug delivery device
US5607461A (en) 1995-10-20 1997-03-04 Nexmed, Inc. Apparatus and method for delivering electrical stimulus to tissue
US5618275A (en) 1995-10-27 1997-04-08 Sonex International Corporation Ultrasonic method and apparatus for cosmetic and dermatological applications
US5755750A (en) 1995-11-13 1998-05-26 University Of Florida Method and apparatus for selectively inhibiting activity in nerve fibers
US5678273A (en) * 1996-03-20 1997-10-21 Porcelli; V. Lorenzo Disposable oral hygiene applicator
FR2747313B1 (en) 1996-04-16 1998-06-05 Lhd Lab Hygiene Dietetique TRANSDERMAL MEDICINE DELIVERY DEVICE BY IONOPHORESIS
US5908401A (en) 1996-05-08 1999-06-01 The Aps Organization, Llp Method for iontophoretic delivery of antiviral agents
US6385487B1 (en) * 1996-05-08 2002-05-07 Biophoretic Therapeutic Systems, Llc Methods for electrokinetic delivery of medicaments
US5676648A (en) * 1996-05-08 1997-10-14 The Aps Organization, Llp Iontophoretic drug delivery apparatus and method for use
WO1997048444A1 (en) 1996-06-19 1997-12-24 Becton Dickinson And Company Iontophoretic delivery of cell adhesion inhibitors
US5797867A (en) 1996-09-27 1998-08-25 Becton Dickinson And Company Iontophoretic drug delivery system, including method for activating same for attachment to patient
US5713846A (en) 1996-09-27 1998-02-03 Becton Dickinson And Company Iontophoretic drug delivery system, including method for activating same for attachment to patient
ATE274972T1 (en) * 1996-12-26 2004-09-15 Elan Internat Services Ltd ELECTRODE UNIT FOR A DEVICE FOR ADMINISTRATION OF MEDICATION
US6018679A (en) 1997-01-29 2000-01-25 Novartis Finance Corp. Iontophoretic transdermal delivery and control of adverse side-effects
US5794774A (en) * 1997-05-12 1998-08-18 Porcelli; V. Lorenzo Disposable oral hygiene applicator
US5911319A (en) * 1997-05-12 1999-06-15 John J. Stoltzfus Blister package for oral hygiene applicators
US5904712A (en) 1997-06-12 1999-05-18 Axelgaard Manufacturing Co., Ltd. Current-controlling electrode
US5846217A (en) 1997-07-29 1998-12-08 Iomed, Inc. Iontophoretic bioelectrode and method of using same
US5899876A (en) 1997-08-27 1999-05-04 Becton, Dickinson And Company Multiple site drug delivery system
TW368420B (en) 1997-11-04 1999-09-01 Genetronics Inc Apparatus and method for transdermal molecular delivery by applying sufficient amplitude of electric field to induce migration of molecules through pores in the stratum corneum
US5968005A (en) 1998-01-07 1999-10-19 Tu; Hosheng Devices and means for treating canker sores
IL122875A0 (en) * 1998-01-08 1998-08-16 S L P Ltd An integrated sleep apnea screening system
US6023639A (en) 1998-05-01 2000-02-08 Hakky; Said Non-invasive bodily fluid withdrawal and monitoring system
JP4297401B2 (en) * 1998-09-15 2009-07-15 トランスポート・ファーマシューティカルズ・インコーポレイテッド Drug delivery electrode by ion osmosis therapy
US6148231A (en) 1998-09-15 2000-11-14 Biophoretic Therapeutic Systems, Llc Iontophoretic drug delivery electrodes and method
US6101411A (en) 1998-09-24 2000-08-08 Newsome; David A. Dilation enhancer
US5931859A (en) 1998-09-30 1999-08-03 Burke; Robert E. Facial toning system
US6148232A (en) 1998-11-09 2000-11-14 Elecsys Ltd. Transdermal drug delivery and analyte extraction
US6477410B1 (en) 2000-05-31 2002-11-05 Biophoretic Therapeutic Systems, Llc Electrokinetic delivery of medicaments
US6553253B1 (en) * 1999-03-12 2003-04-22 Biophoretic Therapeutic Systems, Llc Method and system for electrokinetic delivery of a substance

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