CA2408997A1 - Poly-tri-fluoro-ethoxypolyphosphazene coverings and films for medical devices - Google Patents

Poly-tri-fluoro-ethoxypolyphosphazene coverings and films for medical devices Download PDF

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Publication number
CA2408997A1
CA2408997A1 CA002408997A CA2408997A CA2408997A1 CA 2408997 A1 CA2408997 A1 CA 2408997A1 CA 002408997 A CA002408997 A CA 002408997A CA 2408997 A CA2408997 A CA 2408997A CA 2408997 A1 CA2408997 A1 CA 2408997A1
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CA
Canada
Prior art keywords
medical devices
films
ethoxypolyphosphazene
coverings
fluoro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002408997A
Other languages
French (fr)
Other versions
CA2408997C (en
Inventor
Michael Grunze
Claudia Gries
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Celonova Bioscience Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10019982A external-priority patent/DE10019982A1/en
Application filed by Individual filed Critical Individual
Publication of CA2408997A1 publication Critical patent/CA2408997A1/en
Application granted granted Critical
Publication of CA2408997C publication Critical patent/CA2408997C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G79/00—Macromolecular compounds obtained by reactions forming a linkage containing atoms other than silicon, sulfur, nitrogen, oxygen, and carbon with or without the latter elements in the main chain of the macromolecule
    • C08G79/02—Macromolecular compounds obtained by reactions forming a linkage containing atoms other than silicon, sulfur, nitrogen, oxygen, and carbon with or without the latter elements in the main chain of the macromolecule a linkage containing phosphorus
    • C08G79/025—Polyphosphazenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/08—Materials for coatings
    • A61L29/085—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Vascular Medicine (AREA)
  • Transplantation (AREA)
  • Materials For Medical Uses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Prostheses (AREA)

Abstract

The present invention relates to an anti-thrombogenic, physically well-tolerated polymer and its use for manufacturing sheaths and films as a component of therapeutic devices for preventing excessive cell proliferation. Furthermore, it relates to films made from the polymer as well as wrappings for medical devices such as stents. It also relates to medical devices that are enclosed by a film or wrapping according to the invention.
CA 2408997 2000-04-11 2001-04-10 Poly-tri-fluoro-ethoxypolyphosphazene coverings and films for medical devices Expired - Lifetime CA2408997C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US19608300P 2000-04-11 2000-04-11
US60/196,083 2000-04-11
DE10019982.8 2000-04-22
DE10019982A DE10019982A1 (en) 2000-04-22 2000-04-22 Use of antithrombogenic phosphazene polymer films or coverings on stents, catheters or other implants to reduce cell proliferation and hence to limit restenosis
PCT/DE2001/001398 WO2001080919A2 (en) 2000-04-11 2001-04-10 Poly-tri-fluoro-ethoxypolyphosphazene coverings and films

Publications (2)

Publication Number Publication Date
CA2408997A1 true CA2408997A1 (en) 2002-11-14
CA2408997C CA2408997C (en) 2008-08-05

Family

ID=26005436

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2408997 Expired - Lifetime CA2408997C (en) 2000-04-11 2001-04-10 Poly-tri-fluoro-ethoxypolyphosphazene coverings and films for medical devices

Country Status (10)

Country Link
US (1) US7265199B2 (en)
EP (1) EP1274471B1 (en)
JP (1) JP2004500918A (en)
AT (1) ATE350077T1 (en)
AU (1) AU2001263760A1 (en)
CA (1) CA2408997C (en)
DE (2) DE10191512D2 (en)
DK (1) DK1274471T3 (en)
ES (1) ES2278747T3 (en)
WO (1) WO2001080919A2 (en)

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US20050136093A1 (en) * 2002-07-05 2005-06-23 Polyzenix Gmbh Implant for transport and release for pharmacologically active agents as well as a process for producing the same
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US20210299056A9 (en) 2004-10-25 2021-09-30 Varian Medical Systems, Inc. Color-Coded Polymeric Particles of Predetermined Size for Therapeutic and/or Diagnostic Applications and Related Methods
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US20070255284A1 (en) * 2006-04-28 2007-11-01 Sdgi Holdings, Inc. Orthopedic implant apparatus
JP2010505597A (en) 2006-10-10 2010-02-25 セロノバ バイオサイエンシーズ， インコーポレイテッド Bioprosthetic heart valve using polyphosphazene
CN101646468A (en) * 2006-10-10 2010-02-10 西洛诺瓦生物科学公司 Compositions and devices comrising silicone and specific polyphosphazenes
JP2010526625A (en) * 2007-05-15 2010-08-05 カメレオン バイオサーフェセズ リミテッド Polymer coating on medical devices
CN102176868A (en) * 2008-02-11 2011-09-07 西洛诺瓦生物科学公司 Tissue-fastening articles and devices, and related methods
US20100159195A1 (en) * 2008-12-24 2010-06-24 Quincy Iii Roger B High repellency materials via nanotopography and post treatment

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Also Published As

Publication number Publication date
DE10191512D2 (en) 2003-03-13
WO2001080919A2 (en) 2001-11-01
US7265199B2 (en) 2007-09-04
ES2278747T3 (en) 2007-08-16
JP2004500918A (en) 2004-01-15
CA2408997C (en) 2008-08-05
EP1274471B1 (en) 2007-01-03
EP1274471A2 (en) 2003-01-15
ATE350077T1 (en) 2007-01-15
DE50111797D1 (en) 2007-02-15
WO2001080919A3 (en) 2002-05-23
AU2001263760A1 (en) 2001-11-07
DK1274471T3 (en) 2007-04-02
US20040014936A1 (en) 2004-01-22

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Effective date: 20210412