CA2353486A1 - Glucose monitor calibration methods - Google Patents

Glucose monitor calibration methods Download PDF

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Publication number
CA2353486A1
CA2353486A1 CA002353486A CA2353486A CA2353486A1 CA 2353486 A1 CA2353486 A1 CA 2353486A1 CA 002353486 A CA002353486 A CA 002353486A CA 2353486 A CA2353486 A CA 2353486A CA 2353486 A1 CA2353486 A1 CA 2353486A1
Authority
CA
Canada
Prior art keywords
glucose monitor
monitor data
glucose
calibration characteristics
linear regression
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002353486A
Other languages
French (fr)
Other versions
CA2353486C (en
Inventor
John J. Mastrototaro
Todd M. Gross
John J. Shin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medtronic Minimed Inc
Original Assignee
Minimed, Inc.
John J. Mastrototaro
Todd M. Gross
John J. Shin
Medtronic Minimed, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Minimed, Inc., John J. Mastrototaro, Todd M. Gross, John J. Shin, Medtronic Minimed, Inc. filed Critical Minimed, Inc.
Priority to CA002484583A priority Critical patent/CA2484583C/en
Publication of CA2353486A1 publication Critical patent/CA2353486A1/en
Application granted granted Critical
Publication of CA2353486C publication Critical patent/CA2353486C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
    • A61M5/1723—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure
    • A61M2005/1726—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure the body parameters being measured at, or proximate to, the infusion site

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Molecular Biology (AREA)
  • Optics & Photonics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Indication And Recording Devices For Special Purposes And Tariff Metering Devices (AREA)

Abstract

A method of calibrating glucose monitor data includes collecting the glucose monitor data over a period of time at predetermined intervals. It also includes obtaining at least two reference glucose values from a reference source that temporally correspond with the glucose monitor data obtained at the predetermined intervals. Also included is calculating the calibration characteristics using the reference glucose values and the corresponding glucose monitor data to regress the obtained glucose monitor data. And calibrating the obtained glucose monitor data using the calibration characteristics is included. In preferred embodiments, the reference source is a blood glucose meter (10, 100), and the at least two reference glucose values are obtained from blood tests. In additional embodiments, the calculation of the calibration characteristics is obtained using linear regression and in particular embodiments, least squares linear regression. Alternatively, the calculation of the calibration characteristics is obtained using non-linear regression.
CA002353486A 1999-02-25 2000-02-24 Glucose monitor calibration methods Expired - Fee Related CA2353486C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA002484583A CA2484583C (en) 1999-02-25 2000-02-24 Glucose monitor calibration methods

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US12158499P 1999-02-25 1999-02-25
US09/511,580 US6424847B1 (en) 1999-02-25 2000-02-23 Glucose monitor calibration methods
US60/121,584 2000-02-23
US09/511,580 2000-02-23
PCT/US2000/004666 WO2000049941A1 (en) 1999-02-25 2000-02-24 Glucose monitor calibration methods

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA002484583A Division CA2484583C (en) 1999-02-25 2000-02-24 Glucose monitor calibration methods

Publications (2)

Publication Number Publication Date
CA2353486A1 true CA2353486A1 (en) 2000-08-31
CA2353486C CA2353486C (en) 2005-02-15

Family

ID=26819627

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002353486A Expired - Fee Related CA2353486C (en) 1999-02-25 2000-02-24 Glucose monitor calibration methods

Country Status (8)

Country Link
US (1) US6424847B1 (en)
EP (1) EP1154718B1 (en)
JP (1) JP2002541883A (en)
AT (1) ATE363228T1 (en)
AU (1) AU3243500A (en)
CA (1) CA2353486C (en)
DE (1) DE60035025T2 (en)
WO (1) WO2000049941A1 (en)

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EP1154718A1 (en) 2001-11-21
EP1154718B1 (en) 2007-05-30
DE60035025T2 (en) 2008-01-24
CA2353486C (en) 2005-02-15
US6424847B1 (en) 2002-07-23
ATE363228T1 (en) 2007-06-15
AU3243500A (en) 2000-09-14
WO2000049941A1 (en) 2000-08-31
DE60035025D1 (en) 2007-07-12
JP2002541883A (en) 2002-12-10
WO2000049941A8 (en) 2000-10-26

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