CA2347707A1 - Foldable ophthalmic and otorhinolaryngological device materials - Google Patents

Foldable ophthalmic and otorhinolaryngological device materials Download PDF

Info

Publication number
CA2347707A1
CA2347707A1 CA002347707A CA2347707A CA2347707A1 CA 2347707 A1 CA2347707 A1 CA 2347707A1 CA 002347707 A CA002347707 A CA 002347707A CA 2347707 A CA2347707 A CA 2347707A CA 2347707 A1 CA2347707 A1 CA 2347707A1
Authority
CA
Canada
Prior art keywords
materials
device materials
ophthalmic
intraocular lens
otorhinolaryngological device
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002347707A
Other languages
French (fr)
Other versions
CA2347707C (en
Inventor
Charles Freeman
Douglas C. Schlueter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2347707A1 publication Critical patent/CA2347707A1/en
Application granted granted Critical
Publication of CA2347707C publication Critical patent/CA2347707C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
    • G02B1/04—Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/16—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10—Esters
    • C08F220/26—Esters containing oxygen in addition to the carboxy oxygen
    • C08F220/30—Esters containing oxygen in addition to the carboxy oxygen containing aromatic rings in the alcohol moiety
    • C08F220/301—Esters containing oxygen in addition to the carboxy oxygen containing aromatic rings in the alcohol moiety and one oxygen in the alcohol moiety
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10—Esters
    • C08F220/26—Esters containing oxygen in addition to the carboxy oxygen
    • C08F220/30—Esters containing oxygen in addition to the carboxy oxygen containing aromatic rings in the alcohol moiety
    • C08F220/302—Esters containing oxygen in addition to the carboxy oxygen containing aromatic rings in the alcohol moiety and two or more oxygen atoms in the alcohol moiety
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
    • G02B1/04—Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
    • G02B1/041—Lenses
    • G02B1/043—Contact lenses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/145—Corneal inlays, onlays, or lenses for refractive correction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16—Intraocular lenses

Abstract

Disclosed are soft, high refractive index, acrylic materials having an elongation of at least 150 %. These materials, especially useful as intraocular lens materials, contain an aryl acrylic hydrophobic monomer as the single principal device-forming monomer. In addition to their use as intraocular lens materials, the present materials are also suitable for use in other ophthalmic or otorhinolaryngological devices, such as contact lenses, keratoprostheses, corneal inlays or rings; otological ventilation tubes and nasal implants.
CA002347707A 1999-09-07 2000-08-23 Foldable ophthalmic and otorhinolaryngological device materials Expired - Fee Related CA2347707C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15262299P 1999-09-07 1999-09-07
US60/152,622 1999-09-07
PCT/US2000/023283 WO2001018078A1 (en) 1999-09-07 2000-08-23 Foldable ophthalmic and otorhinolaryngological device materials

Publications (2)

Publication Number Publication Date
CA2347707A1 true CA2347707A1 (en) 2001-03-15
CA2347707C CA2347707C (en) 2009-06-09

Family

ID=22543687

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002347707A Expired - Fee Related CA2347707C (en) 1999-09-07 2000-08-23 Foldable ophthalmic and otorhinolaryngological device materials

Country Status (14)

Country Link
US (2) US6528602B1 (en)
EP (1) EP1210380B1 (en)
JP (3) JP5459816B2 (en)
CN (1) CN1151186C (en)
AR (1) AR025571A1 (en)
AT (1) ATE291045T1 (en)
AU (1) AU766276B2 (en)
BR (1) BR0007069B1 (en)
CA (1) CA2347707C (en)
DE (1) DE60018766T2 (en)
DK (1) DK1210380T3 (en)
ES (1) ES2235935T3 (en)
PT (1) PT1210380E (en)
WO (1) WO2001018078A1 (en)

Families Citing this family (78)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8247511B2 (en) 1999-04-12 2012-08-21 Advanced Vision Science, Inc. Water plasticized high refractive index polymer for ophthalmic applications
US6281319B1 (en) 1999-04-12 2001-08-28 Surgidev Corporation Water plasticized high refractive index polymer for ophthalmic applications
US6723815B2 (en) 1999-09-02 2004-04-20 Alcon, Inc. Covalently-bound, hydrophilic coating compositions for surgical implants
CA2347707C (en) * 1999-09-07 2009-06-09 Alcon Universal Ltd. Foldable ophthalmic and otorhinolaryngological device materials
US8048155B2 (en) 2002-02-02 2011-11-01 Powervision, Inc. Intraocular implant devices
EP1521786B1 (en) * 2002-07-16 2008-04-23 Alcon, Inc. Ophthalmic and otorhinolaryngological device materials
US8328869B2 (en) 2002-12-12 2012-12-11 Powervision, Inc. Accommodating intraocular lenses and methods of use
US10835373B2 (en) 2002-12-12 2020-11-17 Alcon Inc. Accommodating intraocular lenses and methods of use
US8361145B2 (en) 2002-12-12 2013-01-29 Powervision, Inc. Accommodating intraocular lens system having circumferential haptic support and method
US7354980B1 (en) 2004-03-12 2008-04-08 Key Medical Technologies, Inc. High refractive index polymers for ophthalmic applications
US8166299B2 (en) * 2004-07-06 2012-04-24 Andrew Christopher Kemshall Secure messaging
US7157538B2 (en) * 2004-08-13 2007-01-02 Alcon, Inc. Covalently-bound, hydrophilic coating compositions for surgical implants
US20060068207A1 (en) * 2004-09-28 2006-03-30 Brewer Science Inc., A Missouri Corporation Curable high refractive index resins for optoelectronic applications
US7446157B2 (en) 2004-12-07 2008-11-04 Key Medical Technologies, Inc. Nanohybrid polymers for ophthalmic applications
JP2009526894A (en) * 2006-02-14 2009-07-23 プロコルニア ホールディング ビー．ブイ． High refractive index monomer and (co) polymer prepared therefrom
EP1818690A1 (en) * 2006-02-14 2007-08-15 Procornea Holding B.V. Intraocular lenses essentially free from glistenings
US8058323B2 (en) * 2006-07-21 2011-11-15 Novartis Ag Low-tack ophthalmic and otorhinolaryngological device materials
TWI399228B (en) * 2006-07-21 2013-06-21 Alcon Inc Low-tack ophthalmic and otorhinolaryngological device materials
TW200816966A (en) * 2006-07-21 2008-04-16 Alcon Mfg Ltd Low-tack ophthalmic and otorhinolaryngological device materials
US7714039B2 (en) * 2006-07-21 2010-05-11 Alcon, Inc. Low-tack ophthalmic and otorhinolaryngological device materials
MX2009003813A (en) * 2006-10-13 2009-05-12 Alcon Inc Intraocular lenses with unique blue-violet cutoff and blue light transmission characteristics.
CA2683002C (en) * 2007-04-30 2014-05-20 Alcon, Inc. Uv-absorbers for ophthalmic lens materials
US20090001372A1 (en) * 2007-06-29 2009-01-01 Lumination Llc Efficient cooling of lasers, LEDs and photonics devices
US8968396B2 (en) 2007-07-23 2015-03-03 Powervision, Inc. Intraocular lens delivery systems and methods of use
JP5752415B2 (en) 2007-07-23 2015-07-22 パワーヴィジョン・インコーポレーテッド Correction of the refractive power of the lens after implantation
EP2671541B1 (en) 2007-07-23 2019-04-17 PowerVision, Inc. Accommodating intraocular lenses
US8668734B2 (en) 2010-07-09 2014-03-11 Powervision, Inc. Intraocular lens delivery devices and methods of use
ES2365290T3 (en) 2007-07-25 2011-09-28 Alcon, Inc. MATERIALS FOR HIGH INDOOR REFRACTION OPTIONAL DEVICE.
TWI435915B (en) * 2007-08-09 2014-05-01 Alcon Inc Ophthalmic lens materials containing chromophores that absorb both uv and short wavelength visible light
TW200916130A (en) 2007-10-02 2009-04-16 Alcon Inc Ophthalmic and otorhinolaryngological device materials containing an alkylphenol ethoxylate
US7858672B1 (en) 2007-10-02 2010-12-28 Alcon, Inc. Methacrylic materials suitable for ophthalmic and otorhinolaryngological devices
TW200920330A (en) * 2007-10-02 2009-05-16 Alcon Inc Ophthalmic and otorhinolaryngological device materials containing an alkyl ethoxylate
TWI426931B (en) * 2007-10-03 2014-02-21 Alcon Inc Ophthalmic and otorhinolaryngological device materials
TWI461186B (en) * 2007-10-05 2014-11-21 Alcon Inc Ophthalmic and otorhinolaryngological device materials
TWI426932B (en) * 2007-10-05 2014-02-21 Alcon Inc Ophthalmic and otorhinolaryngological device materials
WO2009102454A1 (en) * 2008-02-12 2009-08-20 Aaren Scientific Inc. Ophthalmic lens having a yellow dye light blocking component
TW201000155A (en) * 2008-05-06 2010-01-01 Alcon Inc High refractive index ophthalmic device materials
US7884228B1 (en) * 2008-05-06 2011-02-08 Alcon, Inc. UV-absorbers for ophthalmic lens materials
US7803359B1 (en) 2008-05-06 2010-09-28 Alcon, Inc. UV-absorbers for ophthalmic lens materials
US8043607B2 (en) 2008-07-15 2011-10-25 Novartis Ag UV-absorbers for ophthalmic lens materials
WO2010022108A2 (en) * 2008-08-18 2010-02-25 Envisionier Medical Technologies, Inc. Fluid delivery catheter apparatus
US8945142B2 (en) 2008-08-27 2015-02-03 Cook Medical Technologies Llc Delivery system for implanting nasal ventilation tube
EP2334361A4 (en) * 2008-08-27 2011-10-26 Patrick C Melder Nasal ventilation system and method of using same
US8236053B1 (en) 2008-10-08 2012-08-07 Novartis Ag 2-amino benzophenone UV-absorbers for ophthalmic lens materials
TWI453199B (en) * 2008-11-04 2014-09-21 Alcon Inc Uv/visible light absorbers for ophthalmic lens materials
US10299913B2 (en) 2009-01-09 2019-05-28 Powervision, Inc. Accommodating intraocular lenses and methods of use
US8293858B1 (en) 2009-01-14 2012-10-23 Novartis Ag Ophthalmic and otorhinolaryngological device materials containing a reactive NVP macromer
US8148445B1 (en) 2009-01-14 2012-04-03 Novartis Ag Ophthalmic and otorhinolaryngological device materials containing a multi-arm PEG macromer
TWI464151B (en) * 2009-07-06 2014-12-11 Alcon Inc Uv/visible light absorbers for ophthalmic lens materials
TWI487690B (en) 2009-07-06 2015-06-11 Alcon Inc Visible light absorbers for ophthalmic lens materials
AU2010289896B2 (en) * 2009-08-24 2013-08-29 Alcon Inc. Ophthalmic and otorhinolaryngological device materials
TWI473629B (en) 2010-01-18 2015-02-21 Alcon Inc Visible light absorbers for ophthalmic lens materials
US8900298B2 (en) 2010-02-23 2014-12-02 Powervision, Inc. Fluid for accommodating intraocular lenses
AU2011245400B2 (en) 2010-04-29 2015-01-29 Alcon Inc. Intraocular lenses with combinations of UV absorbers and blue light chromophores
US8362177B1 (en) 2010-05-05 2013-01-29 Novartis Ag High refractive index ophthalmic device materials with reduced tack
TWI473823B (en) 2010-06-21 2015-02-21 Novartis Ag High refractive index, acrylic ophthalmic device materials with reduced glistenings
WO2012004746A2 (en) 2010-07-05 2012-01-12 Polymer Technologies International (Eou) Refractive-diffractive ophthalmic device and compositions useful for producing same
TWI517861B (en) 2011-02-08 2016-01-21 諾華公司 Low-tack, hydrophobic ophthalmic device materials
TWI513768B (en) 2011-06-01 2015-12-21 Novartis Ag Hydrophobic acrylic intraocular lens materials
TWI551646B (en) 2011-06-03 2016-10-01 諾華公司 Hydrophobic acrylic intraocular lens materials
JP5799634B2 (en) 2011-07-22 2015-10-28 株式会社リコー Image processing apparatus and image processing system
TW201311621A (en) 2011-08-15 2013-03-16 Novartis Ag UV-absorbers for ophthalmic lens materials
BR112014006188B1 (en) 2011-09-16 2021-06-08 Benz Research And Development Corp. intraocular lens, composition and method for preparing a composition
US10433949B2 (en) 2011-11-08 2019-10-08 Powervision, Inc. Accommodating intraocular lenses
KR101729677B1 (en) 2012-02-15 2017-04-24 노바르티스 아게 Ophthalmic and otorhinolaryngological device materials containing a multi-arm peg macromer
US8585938B1 (en) 2012-03-30 2013-11-19 Novartis Ag UV-absorbers for ophthalmic lens materials
CN104395387A (en) 2012-06-26 2015-03-04 诺华股份有限公司 2-amino benzophenone UV-absorbers for ophthalmic lens materials
WO2014106866A1 (en) 2013-01-07 2014-07-10 Council Of Scientific & Industrial Research Flexible, high refractive index hydrophobic copolymer
EP2967842B1 (en) 2013-03-15 2020-11-04 Alcon Inc. Method of reconfiguring an intraocular lens for delivery to a delivery device
WO2015084788A1 (en) 2013-12-04 2015-06-11 Novartis Ag Soft acrylic materials with high refractive index and minimized glistening
EP2898920B1 (en) 2014-01-24 2018-06-06 Cook Medical Technologies LLC Articulating balloon catheter
CN106999628A (en) 2014-12-16 2017-08-01 诺华股份有限公司 Hydrophobic acrylic acid's ester acrylamide copolymer for Ophthalmoligic instrument
JP6371480B2 (en) 2014-12-16 2018-08-08 ノバルティス アーゲー Low water content acrylate-acrylamide copolymers for ophthalmic appliances
WO2016133656A1 (en) 2015-02-16 2016-08-25 Novartis Ag Wet-pack intraocular lens materials with high refractive index
EP3370647B8 (en) 2015-11-06 2021-06-30 Alcon Inc. Accommodating intraocular lenses and methods of manufacturing
RU2728693C1 (en) 2017-06-05 2020-07-31 Алькон Инк. Materials for intraocular lens with high refraction index and high abbe number
EP4041131A4 (en) 2019-10-04 2023-11-15 Alcon Inc. Adjustable intraocular lenses and methods of post-operatively adjusting intraocular lenses
CN111154028A (en) * 2020-01-06 2020-05-15 东南大学 High-refractive-index corneal contact lens material and application thereof

Family Cites Families (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3850892A (en) 1972-01-03 1974-11-26 Biocontacts Physiologically compatible plastic contact lenses and a method for their production
US4304895A (en) 1973-06-20 1981-12-08 Wesley-Jessen, Inc. Ultraviolet absorbing corneal contact lenses
AR207867A1 (en) 1974-07-04 1976-11-08 Smith & Nephew Res A LIGHTLY INTERLACED HYDROGEL COPOLYMER
US4260954A (en) 1979-01-26 1981-04-07 Barcus-Berry, Inc. Amplifier load correction system
US4267295A (en) 1979-02-09 1981-05-12 Syntex (U.S.A.) Inc. Polymeric compositions and hydrogels formed therefrom
US4452776A (en) 1979-08-20 1984-06-05 Eye Research Institute Of Retina Foundation Hydrogel implant article and method
JPS6017404B2 (en) 1980-12-15 1985-05-02 ホ−ヤ株式会社 Low dispersion high refractive index lens
US4405773A (en) 1982-02-05 1983-09-20 Schering Corporation Hydrophylic contact lenses and methods for making same
US5507805A (en) 1982-05-03 1996-04-16 American Cyanamid Company Intraocular lens and method of retaining in place
DE3376267D1 (en) 1982-11-11 1988-05-19 Showa Denko Kk POLYMERIZABLE COMPOSITIONS
JPS59195621A (en) 1983-04-22 1984-11-06 Toyo Contact Lens Co Ltd Soft contact lens
US4528311A (en) 1983-07-11 1985-07-09 Iolab Corporation Ultraviolet absorbing polymers comprising 2-hydroxy-5-acrylyloxyphenyl-2H-benzotriazoles
US4664666A (en) 1983-08-30 1987-05-12 Ezekiel Nominees Pty. Ltd. Intraocular lens implants
EP0391452B1 (en) 1983-08-30 1994-01-05 Ezekiel Nominees Pty.Ltd. Intraocular lens implants
CA1252249A (en) * 1983-09-24 1989-04-04 Teruo Sakagami Halogen-containing resin lens material
JPS60200011A (en) 1984-03-21 1985-10-09 Matsushita Electric Ind Co Ltd Liquid fuel burner
US4620954A (en) 1985-06-07 1986-11-04 Ciba Vision Care Corp. Hydrogel from ultraviolet-initiated copolymerization
JPS62111229A (en) 1985-11-11 1987-05-22 Hoya Corp Soft contact lens
US4676792A (en) 1986-08-26 1987-06-30 Donald Praeger Method and artificial intraocular lens device for the phakic treatment of myopia
JPH0622565B2 (en) 1986-10-28 1994-03-30 株式会社メニコン Intraocular lens material
DE3784152T3 (en) 1986-12-26 1997-03-20 Nippon Catalytic Chem Ind High refractive index resin, process for its production and optical materials made from this resin.
NL8701548A (en) 1987-07-01 1989-02-01 Tno POLYMER NETWORK, METHOD FOR THE PREPARATION THEREOF, THE USE THEREOF FOR CLADING AND / OR IMPREGNATING OR FOR MANUFACTURING EYE LENSES, AND FORMED PROPERTIES, WHOLLY OR FROM AN EXISTINGLY PROVEN POLISH.
US4834750A (en) 1987-09-17 1989-05-30 Ioptex Research, Inc. Deformable-elastic intraocular lens
US5269813A (en) 1990-06-12 1993-12-14 Menicon Co., Ltd. Material for one-piece intraocular lenses
JP2724931B2 (en) * 1990-11-07 1998-03-09 ネッスル エス エー Copolymer and intraocular lens using the copolymer
US5290892A (en) * 1990-11-07 1994-03-01 Nestle S.A. Flexible intraocular lenses made from high refractive index polymers
JPH05310A (en) 1991-06-26 1993-01-08 Kobe Steel Ltd Wiper device for hot rolling mill and method for controlling the same
US5341974A (en) 1992-06-19 1994-08-30 Mont-Bell Co., Ltd. Back bag
US5331073A (en) 1992-11-09 1994-07-19 Allergan, Inc. Polymeric compositions and intraocular lenses made from same
JP3108550B2 (en) 1992-11-11 2000-11-13 株式会社メニコン Soft ophthalmic lens material
US5470932A (en) 1993-10-18 1995-11-28 Alcon Laboratories, Inc. Polymerizable yellow dyes and their use in opthalmic lenses
US5451651A (en) 1993-12-17 1995-09-19 Bausch & Lomb Incorporated Urea and urethane monomers for contact lens materials
SE9403392D0 (en) 1994-10-06 1994-10-06 Pharmacia Ab Intraocular lens materials
WO1996040303A1 (en) * 1995-06-07 1996-12-19 Alcon Laboratories, Inc. Improved high refractive index ophthalmic lens materials
US5654350A (en) 1995-06-07 1997-08-05 Johnson & Johnson Vision Products, Inc. Contact lenses with hydrophilic crosslinkers
SE9600006D0 (en) 1996-01-02 1996-01-02 Pharmacia Ab Foldable intraocular lens materials
US5922821A (en) * 1996-08-09 1999-07-13 Alcon Laboratories, Inc. Ophthalmic lens polymers
JP2000516520A (en) * 1997-05-29 2000-12-12 アルコン ラボラトリーズ，インコーポレイテッド Materials used in glaucoma filtration devices
US5891931A (en) 1997-08-07 1999-04-06 Alcon Laboratories, Inc. Method of preparing foldable high refractive index acrylic ophthalmic device materials
JP2001512754A (en) * 1997-08-12 2001-08-28 アルコン ラボラトリーズ インコーポレイテッド Ophthalmic lens polymer
JP3641110B2 (en) 1997-08-20 2005-04-20 株式会社メニコン Materials for soft intraocular lenses
JP4144920B2 (en) 1997-08-20 2008-09-03 興和株式会社 Soft intraocular lens material
DE19738345C1 (en) 1997-09-02 1999-05-06 Mdp Medical Device Polymers Gm intraocular lens
CN1213671A (en) 1997-10-07 1999-04-14 参天制药株式会社 Four-component copolymer and eye lens formed by same
JP2002511597A (en) * 1998-04-15 2002-04-16 アルコン ラボラトリーズ， インコーポレイテッド High refractive index ophthalmic device materials
BR9909618A (en) * 1998-04-15 2000-12-12 Alcon Lab Inc High refractive index ophthalmic device materials prepared using a post-polymerization crosslinking process
EP1079870B1 (en) * 1998-04-15 2001-11-14 Alcon Laboratories, Inc. Bicomposite intraocular lens and method for its preparation
AU760960B2 (en) 1998-10-29 2003-05-22 Advanced Medical Optics, Inc. Intraocular lenses made from polymeric compositions
US6245106B1 (en) 1998-10-29 2001-06-12 Allergan Sales, Inc. Intraocular lenses made from polymeric compositions and monomers useful in said compositions
US6329485B1 (en) 1998-12-11 2001-12-11 Bausch & Lomb Incorporated High refractive index hydrogel compositions for ophthalmic implants
US6281319B1 (en) 1999-04-12 2001-08-28 Surgidev Corporation Water plasticized high refractive index polymer for ophthalmic applications
WO2000079312A1 (en) 1999-06-17 2000-12-28 Bausch & Lomb Surgical, Inc. High refractive index compositions for ophthalmic implants
US6271281B1 (en) 1999-08-26 2001-08-07 Medennium, Inc. Homopolymers containing stable elasticity inducing crosslinkers and ocular implants made therefrom
CA2347707C (en) * 1999-09-07 2009-06-09 Alcon Universal Ltd. Foldable ophthalmic and otorhinolaryngological device materials
CA2381177A1 (en) * 1999-09-07 2001-03-15 Charles Freeman Ophthalmic and otorhinolaryngological device materials

Also Published As

Publication number Publication date
CN1353726A (en) 2002-06-12
JP2011161261A (en) 2011-08-25
BR0007069A (en) 2001-07-31
DE60018766D1 (en) 2005-04-21
AR025571A1 (en) 2002-12-04
CN1151186C (en) 2004-05-26
US20030130460A1 (en) 2003-07-10
DK1210380T3 (en) 2005-05-30
JP2014042846A (en) 2014-03-13
EP1210380B1 (en) 2005-03-16
US6528602B1 (en) 2003-03-04
JP5459816B2 (en) 2014-04-02
CA2347707C (en) 2009-06-09
ES2235935T3 (en) 2005-07-16
US6653422B2 (en) 2003-11-25
WO2001018078A1 (en) 2001-03-15
AU766276B2 (en) 2003-10-16
JP2003508187A (en) 2003-03-04
DE60018766T2 (en) 2005-08-11
EP1210380A1 (en) 2002-06-05
BR0007069B1 (en) 2010-02-09
PT1210380E (en) 2005-05-31
ATE291045T1 (en) 2005-04-15
AU6934700A (en) 2001-04-10

Similar Documents

Publication Publication Date Title
CA2347707A1 (en) Foldable ophthalmic and otorhinolaryngological device materials
BR0013779A (en) Ophthalmological and otorhinolaryngological device materials
KR20050057384A (en) Elastomeric, expandable hydrogel compositions
CA2361827A1 (en) Multifocal ophthalmic lens with reduced halo size
DE69002386T2 (en) Optical component, for example an intraocular implant or contact lens for the correction of an individual's vision.
US7281794B2 (en) Disposable ophthalmic lens
TW374771B (en) Copolymers and an ophthalmic/intraocular lens comprising the same improved soft, high refractive index, acrylic materials having an elongation of at least 150%
ATE332155T1 (en) CROSSLINKERS CONTAINING HOMOPOLYMERS AND EYECULAR IMPLANT MADE THEREFROM
CY1106419T1 (en) LENS CONVERSION SYSTEM FOR TELEOPTIC OR REFRACTOR ARRANGEMENTS
BR0110514A (en) Binocular Lens Systems
FI935486A0 (en) The ophthalmic lens is styrofoam from the pupil
ATE202706T1 (en) USE OF 9-DEOXYPROSTAGLAND INDERIVATIVES FOR THE TREATMENT OF GLAUCOMA
AR030674A1 (en) METHOD FOR DETERMINING THE PRESCRIPTION OF A PATIENT'S VISION
ATE444501T1 (en) OPHTHALMIC LENS SYSTEMS
ATE418560T1 (en) AROMATIC BASED SILYL MONOMERS WITH HIGH REFRACTIVE INDEX
WO2004054469A3 (en) Intraocular implants
WO2004055113A8 (en) High refractive index polysiloxane prepolymers
WO2003022174A3 (en) Intraocular lens extracting device
WO2005057252A3 (en) Interactive refractor incorporating wavefront sensing and adaptive optics
WO2006013579A8 (en) A retinal or fundus camera
AU2002240463A1 (en) Use of endostatin in the treatment of ocular neovascularization
EP2062872A3 (en) Use of bis-amines to enhance the antimicrobial activity of aqueous compositions
WO2004054630A8 (en) Quaternary ammonium esters for disinfection and preservation
DE68919244T2 (en) Wettable, hard, gas-permeable, non-swelling contact lens.
EP1127575A3 (en) Ocular tissue regeneration inducer

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20180823