CA2334269A1 - Diagnostic assay requiring a small sample of biological fluid - Google Patents
Diagnostic assay requiring a small sample of biological fluid Download PDFInfo
- Publication number
- CA2334269A1 CA2334269A1 CA002334269A CA2334269A CA2334269A1 CA 2334269 A1 CA2334269 A1 CA 2334269A1 CA 002334269 A CA002334269 A CA 002334269A CA 2334269 A CA2334269 A CA 2334269A CA 2334269 A1 CA2334269 A1 CA 2334269A1
- Authority
- CA
- Canada
- Prior art keywords
- sample
- optical reading
- opening
- reading chamber
- layer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5302—Apparatus specially adapted for immunological test procedures
- G01N33/5304—Reaction vessels, e.g. agglutination plates
Abstract
An article and a method for monitoring the concentration of glucose in blood. In one aspect, the invention involves an article comprising a multiple-layer element utilizing reagents capable of reacting with an analyte of interest. In a prefered embodiment, the element comprises: (a) a core layer having two major surfaces, an optical reading chamber extending from a first opening in one of said two major surfaces to a second opening in the other of said two major surfaces, said core layer further having a third opening therein and a flow channel, one end of which flow channel communicates with the third opening and the other end of which flow channel communicates with the optical reading chamber; and (b) a base layer in face-to-face contact with one major surface of said core layer; and (c) a cover layer in face-to-face contact with the other major surface of said core layer, said cover layer having an opening therein to vent the element. In this embodiment, the optical reading chamber extends completely through the core layer. The sample is introduced into the third opening and then flows through the flow channel into the optical reading chamber. The reagents with which the analyte in the sample reacts to form an optically detectable reaction product can be disposed in the optical reading chamber or can be added to the sample before the sample enters the optical reading chamber. In another aspect, the invention involves a method comprising the steps of:
(a) obtaining a sample of biological fluid, e.g., interstitial fluid, from the body of a patient; (b) introducing the sample to article comprising a multiple-layer element having an optical reading chamber, (c) allowing reagents to react with an analyte of interest in the sample; and (d) measuring the concentration of analyte in the sample by means of an optical instrument.
(a) obtaining a sample of biological fluid, e.g., interstitial fluid, from the body of a patient; (b) introducing the sample to article comprising a multiple-layer element having an optical reading chamber, (c) allowing reagents to react with an analyte of interest in the sample; and (d) measuring the concentration of analyte in the sample by means of an optical instrument.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/095,683 US6077660A (en) | 1998-06-10 | 1998-06-10 | Diagnostic assay requiring a small sample of biological fluid |
US09/095,683 | 1998-06-10 | ||
PCT/US1999/012294 WO1999064620A2 (en) | 1998-06-10 | 1999-06-03 | Diagnostic assay requiring a small sample of biological fluid |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2334269A1 true CA2334269A1 (en) | 1999-12-16 |
CA2334269C CA2334269C (en) | 2008-08-19 |
Family
ID=22253133
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002334269A Expired - Lifetime CA2334269C (en) | 1998-06-10 | 1999-06-03 | Diagnostic assay requiring a small sample of biological fluid |
Country Status (10)
Country | Link |
---|---|
US (1) | US6077660A (en) |
EP (1) | EP1102991B1 (en) |
JP (1) | JP2003534526A (en) |
AT (1) | ATE227848T1 (en) |
AU (1) | AU766762B2 (en) |
CA (1) | CA2334269C (en) |
DE (2) | DE69903954T2 (en) |
ES (1) | ES2187165T3 (en) |
IT (1) | ITMI20070307U1 (en) |
WO (1) | WO1999064620A2 (en) |
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US10022078B2 (en) | 2004-07-13 | 2018-07-17 | Dexcom, Inc. | Analyte sensor |
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US7727181B2 (en) * | 2002-10-09 | 2010-06-01 | Abbott Diabetes Care Inc. | Fluid delivery device with autocalibration |
DE60336834D1 (en) | 2002-10-09 | 2011-06-01 | Abbott Diabetes Care Inc | FUEL FEEDING DEVICE, SYSTEM AND METHOD |
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US7645421B2 (en) | 2003-06-20 | 2010-01-12 | Roche Diagnostics Operations, Inc. | System and method for coding information on a biosensor test strip |
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US7645373B2 (en) | 2003-06-20 | 2010-01-12 | Roche Diagnostic Operations, Inc. | System and method for coding information on a biosensor test strip |
US8058077B2 (en) | 2003-06-20 | 2011-11-15 | Roche Diagnostics Operations, Inc. | Method for coding information on a biosensor test strip |
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US9247900B2 (en) | 2004-07-13 | 2016-02-02 | Dexcom, Inc. | Analyte sensor |
US7569126B2 (en) | 2004-06-18 | 2009-08-04 | Roche Diagnostics Operations, Inc. | System and method for quality assurance of a biosensor test strip |
CN101180093B (en) | 2005-03-21 | 2012-07-18 | 雅培糖尿病护理公司 | Method and system for providing integrated medication infusion and analyte monitoring system |
US7768408B2 (en) | 2005-05-17 | 2010-08-03 | Abbott Diabetes Care Inc. | Method and system for providing data management in data monitoring system |
US7620437B2 (en) | 2005-06-03 | 2009-11-17 | Abbott Diabetes Care Inc. | Method and apparatus for providing rechargeable power in data monitoring and management systems |
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EP1937832A4 (en) * | 2005-09-13 | 2008-09-10 | Home Diagnostics Inc | Method of manufacturing a diagnostic test strip |
US7756561B2 (en) | 2005-09-30 | 2010-07-13 | Abbott Diabetes Care Inc. | Method and apparatus for providing rechargeable power in data monitoring and management systems |
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US8801631B2 (en) | 2005-09-30 | 2014-08-12 | Intuity Medical, Inc. | Devices and methods for facilitating fluid transport |
US7583190B2 (en) | 2005-10-31 | 2009-09-01 | Abbott Diabetes Care Inc. | Method and apparatus for providing data communication in data monitoring and management systems |
US8344966B2 (en) | 2006-01-31 | 2013-01-01 | Abbott Diabetes Care Inc. | Method and system for providing a fault tolerant display unit in an electronic device |
US8579853B2 (en) | 2006-10-31 | 2013-11-12 | Abbott Diabetes Care Inc. | Infusion devices and methods |
CA2715628A1 (en) | 2008-02-21 | 2009-08-27 | Dexcom, Inc. | Systems and methods for processing, transmitting and displaying sensor data |
US8262874B2 (en) * | 2008-04-14 | 2012-09-11 | Abbott Diabetes Care Inc. | Biosensor coating composition and methods thereof |
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US8467972B2 (en) | 2009-04-28 | 2013-06-18 | Abbott Diabetes Care Inc. | Closed loop blood glucose control algorithm analysis |
AU2010257118B2 (en) | 2009-06-04 | 2014-08-28 | Lockheed Martin Corporation | Multiple-sample microfluidic chip for DNA analysis |
DK3173014T3 (en) | 2009-07-23 | 2021-09-13 | Abbott Diabetes Care Inc | Real-time control of data on physiological control of glucose levels |
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US9322054B2 (en) | 2012-02-22 | 2016-04-26 | Lockheed Martin Corporation | Microfluidic cartridge |
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US9121050B2 (en) | 2013-03-15 | 2015-09-01 | American Sterilizer Company | Non-enzyme based detection method for electronic monitoring of biological indicator |
CA2912283A1 (en) | 2013-06-21 | 2014-12-21 | Intuity Medical, Inc. | Analyte monitoring system with audible feedback |
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JPWO2021192952A1 (en) * | 2020-03-23 | 2021-09-30 |
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-
1998
- 1998-06-10 US US09/095,683 patent/US6077660A/en not_active Expired - Lifetime
-
1999
- 1999-06-03 DE DE69903954T patent/DE69903954T2/en not_active Revoked
- 1999-06-03 WO PCT/US1999/012294 patent/WO1999064620A2/en not_active Application Discontinuation
- 1999-06-03 CA CA002334269A patent/CA2334269C/en not_active Expired - Lifetime
- 1999-06-03 AU AU44145/99A patent/AU766762B2/en not_active Expired
- 1999-06-03 ES ES99927176T patent/ES2187165T3/en not_active Expired - Lifetime
- 1999-06-03 DE DE29924971U patent/DE29924971U1/en not_active Expired - Lifetime
- 1999-06-03 EP EP99927176A patent/EP1102991B1/en not_active Revoked
- 1999-06-03 AT AT99927176T patent/ATE227848T1/en not_active IP Right Cessation
- 1999-06-03 JP JP2000553610A patent/JP2003534526A/en active Pending
-
2007
- 2007-09-14 IT IT000307U patent/ITMI20070307U1/en unknown
Also Published As
Publication number | Publication date |
---|---|
DE69903954T2 (en) | 2003-09-04 |
AU766762B2 (en) | 2003-10-23 |
ATE227848T1 (en) | 2002-11-15 |
EP1102991B1 (en) | 2002-11-13 |
DE69903954D1 (en) | 2002-12-19 |
AU4414599A (en) | 1999-12-30 |
ITMI20070307U1 (en) | 2008-12-11 |
CA2334269C (en) | 2008-08-19 |
JP2003534526A (en) | 2003-11-18 |
US6077660A (en) | 2000-06-20 |
ES2187165T3 (en) | 2003-05-16 |
WO1999064620A3 (en) | 2001-01-18 |
DE29924971U1 (en) | 2007-07-19 |
WO1999064620A2 (en) | 1999-12-16 |
EP1102991A2 (en) | 2001-05-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKEX | Expiry |
Effective date: 20190603 |