CA2282007A1 - Neural transplantation delivery system - Google Patents

Neural transplantation delivery system Download PDF

Info

Publication number
CA2282007A1
CA2282007A1 CA002282007A CA2282007A CA2282007A1 CA 2282007 A1 CA2282007 A1 CA 2282007A1 CA 002282007 A CA002282007 A CA 002282007A CA 2282007 A CA2282007 A CA 2282007A CA 2282007 A1 CA2282007 A1 CA 2282007A1
Authority
CA
Canada
Prior art keywords
cannula
transplantation
microinjector
syringe barrel
delivery system
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002282007A
Other languages
French (fr)
Other versions
CA2282007C (en
Inventor
Ivar Mendez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Queen Elizabeth II Health Sciences Centre
Original Assignee
Queen Elizabeth II Health Sciences Centre
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Queen Elizabeth II Health Sciences Centre filed Critical Queen Elizabeth II Health Sciences Centre
Priority to CA002282007A priority Critical patent/CA2282007C/en
Priority to US10/088,047 priority patent/US7137969B1/en
Priority to PCT/CA2000/000614 priority patent/WO2001017585A1/en
Priority to AU49057/00A priority patent/AU4905700A/en
Publication of CA2282007A1 publication Critical patent/CA2282007A1/en
Application granted granted Critical
Publication of CA2282007C publication Critical patent/CA2282007C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34—Trocars; Puncturing needles
    • A61B17/3403—Needle locating or guiding means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34—Trocars; Puncturing needles
    • A61B17/3478—Endoscopic needles, e.g. for infusion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/10—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges for stereotaxic surgery, e.g. frame-based stereotaxis
    • A61B90/11—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges for stereotaxic surgery, e.g. frame-based stereotaxis with guides for needles or instruments, e.g. arcuate slides or ball joints
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/06—Head
    • A61M2210/0693—Brain, cerebrum

Abstract

A device and method for neural transplantation in the human brain comprising a microinjector (1), transplantation cannula (2) and bullet guide (16) is disclosed. The microinjector (1) is designed to connect to the proximal end of a syringe barrel (7) and plunger (12) while the transplantation cannula (2) interfaces with the distal end of the syringe barrel (7). In combination, the microinjector (1) and transplantation cannula (2) permit the delivery of multiple cell grafts in a three-dimensional array using a unique spiral technique. The bullet guide (16), which is attachable to a commercially available stereotactic frame, is a multiple channel adapter that functions as a mechanical guiding system for the transplantation cannula (2) and permits plural, spaced deployment of the cannula (2) without adjusting or disturbing the frame.
CA002282007A 1999-09-09 1999-09-09 Neural transplantation delivery system Expired - Lifetime CA2282007C (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA002282007A CA2282007C (en) 1999-09-09 1999-09-09 Neural transplantation delivery system
US10/088,047 US7137969B1 (en) 1999-09-09 2000-05-26 Neural transplantation delivery system
PCT/CA2000/000614 WO2001017585A1 (en) 1999-09-09 2000-05-26 Neural transplantation delivery system
AU49057/00A AU4905700A (en) 1999-09-09 2000-05-26 Neural transplantation delivery system

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA002282007A CA2282007C (en) 1999-09-09 1999-09-09 Neural transplantation delivery system

Publications (2)

Publication Number Publication Date
CA2282007A1 true CA2282007A1 (en) 2001-01-16
CA2282007C CA2282007C (en) 2002-05-28

Family

ID=4164108

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002282007A Expired - Lifetime CA2282007C (en) 1999-09-09 1999-09-09 Neural transplantation delivery system

Country Status (4)

Country Link
US (1) US7137969B1 (en)
AU (1) AU4905700A (en)
CA (1) CA2282007C (en)
WO (1) WO2001017585A1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009100527A1 (en) * 2008-02-11 2009-08-20 Ivar Mendez Injection delivery system
CN115590588A (en) * 2022-09-26 2023-01-13 中国人民解放军总医院第七医学中心（Cn） A intra-abdominal cavity strutting arrangement for among neonate's laparoscopic surgery

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7740593B2 (en) 2005-12-09 2010-06-22 Senorx, Inc Guide block for biopsy or surgical devices
WO2008067183A1 (en) * 2006-11-30 2008-06-05 University Of Pittsburgh - Of The Commonwealth System Of Higher Education A device for cell delivery into the brain or body
US20080255582A1 (en) * 2007-04-11 2008-10-16 Harris John F Methods and Template Assembly for Implanting an Electrode Array in a Patient
CN101342085B (en) * 2007-07-09 2012-10-10 王迎峰 Apparatus for implantation of tissue sticking patch
US20090171168A1 (en) 2007-12-28 2009-07-02 Leyde Kent W Systems and Method for Recording Clinical Manifestations of a Seizure
US9259591B2 (en) 2007-12-28 2016-02-16 Cyberonics, Inc. Housing for an implantable medical device
US8551074B2 (en) * 2008-09-08 2013-10-08 Bayer Pharma AG Connector system having a compressible sealing element and a flared fluid path element
CN102215760A (en) * 2008-11-12 2011-10-12 皇家飞利浦电子股份有限公司 Neurosurgical guiding tool
CN102657548B (en) * 2012-04-25 2014-04-02 天津大学 Reversing nuclear magnetic compatible puncture needle clamp
EP3419715B1 (en) * 2016-02-26 2021-09-15 Neuronano AB Method of implantation of cell aggregates and tissue fragments
WO2018044933A1 (en) 2016-08-30 2018-03-08 The Regents Of The University Of California Methods for biomedical targeting and delivery and devices and systems for practicing the same
WO2018125829A1 (en) 2016-12-28 2018-07-05 Sanbio, Inc. Cell delivery system and methods of operation thereof
CN111132626B (en) 2017-07-17 2024-01-30 沃雅戈治疗公司 Track array guidance system
US20220233767A1 (en) * 2019-05-31 2022-07-28 Rainbow Inc. Puncture needle, puncture needle kit, and stereotactic brain surgery device

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4415101A (en) * 1982-01-22 1983-11-15 Shapiro Justin J Incremental liquid dispensing device
US4518387A (en) * 1982-12-27 1985-05-21 Frank Murphy Syringe injection apparatus with adjustable dosage indicator
US4710180A (en) * 1986-10-06 1987-12-01 Johnson Gerald W Lipoject needle
US6231591B1 (en) 1991-10-18 2001-05-15 2000 Injectx, Inc. Method of localized fluid therapy
US6461296B1 (en) * 1998-06-26 2002-10-08 2000 Injectx, Inc. Method and apparatus for delivery of genes, enzymes and biological agents to tissue cells
SE9601974L (en) * 1996-05-23 1997-10-13 Elekta Ab Device for injecting a substance into a body, especially human or animal
US5792110A (en) * 1996-06-26 1998-08-11 Cunningham; Miles G. Systems and methods for delivering therapeutic agents to selected sites in a subject

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009100527A1 (en) * 2008-02-11 2009-08-20 Ivar Mendez Injection delivery system
US8753314B2 (en) 2008-02-11 2014-06-17 Ivar Mendez Injection delivery system
US9067028B2 (en) 2008-02-11 2015-06-30 Ivar Mendez Injection delivery system
CN115590588A (en) * 2022-09-26 2023-01-13 中国人民解放军总医院第七医学中心（Cn） A intra-abdominal cavity strutting arrangement for among neonate's laparoscopic surgery
CN115590588B (en) * 2022-09-26 2024-01-12 中国人民解放军总医院第七医学中心 Intraperitoneal supporting device used in laparoscopic surgery of newborn

Also Published As

Publication number Publication date
WO2001017585A1 (en) 2001-03-15
AU4905700A (en) 2001-04-10
CA2282007C (en) 2002-05-28
US7137969B1 (en) 2006-11-21

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Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry

Effective date: 20190909