CA2271800C - Intervertebral prosthetic device - Google Patents
Intervertebral prosthetic device Download PDFInfo
- Publication number
- CA2271800C CA2271800C CA002271800A CA2271800A CA2271800C CA 2271800 C CA2271800 C CA 2271800C CA 002271800 A CA002271800 A CA 002271800A CA 2271800 A CA2271800 A CA 2271800A CA 2271800 C CA2271800 C CA 2271800C
- Authority
- CA
- Canada
- Prior art keywords
- prosthetic device
- fixation
- plate
- compressible
- fixation member
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
- A61F2/442—Intervertebral or spinal discs, e.g. resilient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/02—Surgical instruments, devices or methods, e.g. tourniquets for holding wounds open; Tractors
- A61B17/025—Joint distractors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/02—Surgical instruments, devices or methods, e.g. tourniquets for holding wounds open; Tractors
- A61B17/025—Joint distractors
- A61B2017/0256—Joint distractors for the spine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30721—Accessories
- A61F2/30749—Fixation appliances for connecting prostheses to the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
- A61F2002/2835—Bone graft implants for filling a bony defect or an endoprosthesis cavity, e.g. by synthetic material or biological material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30108—Shapes
- A61F2002/3011—Cross-sections or two-dimensional shapes
- A61F2002/30112—Rounded shapes, e.g. with rounded corners
- A61F2002/30125—Rounded shapes, e.g. with rounded corners elliptical or oval
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30108—Shapes
- A61F2002/3011—Cross-sections or two-dimensional shapes
- A61F2002/30138—Convex polygonal shapes
- A61F2002/30158—Convex polygonal shapes trapezoidal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30108—Shapes
- A61F2002/30199—Three-dimensional shapes
- A61F2002/30224—Three-dimensional shapes cylindrical
- A61F2002/30225—Flat cylinders, i.e. discs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30108—Shapes
- A61F2002/30199—Three-dimensional shapes
- A61F2002/30224—Three-dimensional shapes cylindrical
- A61F2002/3023—Three-dimensional shapes cylindrical wedge-shaped cylinders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30317—The prosthesis having different structural features at different locations within the same prosthesis
- A61F2002/30324—The prosthesis having different structural features at different locations within the same prosthesis differing in thickness
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30317—The prosthesis having different structural features at different locations within the same prosthesis
- A61F2002/30327—The prosthesis having different structural features at different locations within the same prosthesis differing in diameter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30329—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30329—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
- A61F2002/30331—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements made by longitudinally pushing a protrusion into a complementarily-shaped recess, e.g. held by friction fit
- A61F2002/30354—Cylindrically-shaped protrusion and recess, e.g. cylinder of circular basis
-
- A—HUMAN NECESSITIES
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30329—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
- A61F2002/30331—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements made by longitudinally pushing a protrusion into a complementarily-shaped recess, e.g. held by friction fit
- A61F2002/30362—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements made by longitudinally pushing a protrusion into a complementarily-shaped recess, e.g. held by friction fit with possibility of relative movement between the protrusion and the recess
- A61F2002/3037—Translation along the common longitudinal axis, e.g. piston
- A61F2002/30373—Translation along the common longitudinal axis, e.g. piston with additional means for preventing said translation
-
- A—HUMAN NECESSITIES
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30329—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
- A61F2002/30433—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements using additional screws, bolts, dowels, rivets or washers e.g. connecting screws
-
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30329—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
- A61F2002/30476—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements locked by an additional locking mechanism
- A61F2002/30492—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements locked by an additional locking mechanism using a locking pin
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- A—HUMAN NECESSITIES
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
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- A61F2002/30329—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
- A61F2002/30476—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements locked by an additional locking mechanism
- A61F2002/30507—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements locked by an additional locking mechanism using a threaded locking member, e.g. a locking screw or a set screw
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
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- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30535—Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30537—Special structural features of bone or joint prostheses not otherwise provided for adjustable
- A61F2002/30546—Special structural features of bone or joint prostheses not otherwise provided for adjustable for adjusting elasticity, flexibility, spring rate or mechanical tension
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30535—Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30537—Special structural features of bone or joint prostheses not otherwise provided for adjustable
- A61F2002/3055—Special structural features of bone or joint prostheses not otherwise provided for adjustable for adjusting length
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- A—HUMAN NECESSITIES
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30535—Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30563—Special structural features of bone or joint prostheses not otherwise provided for having elastic means or damping means, different from springs, e.g. including an elastomeric core or shock absorbers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00179—Ceramics or ceramic-like structures
- A61F2310/00185—Ceramics or ceramic-like structures based on metal oxides
- A61F2310/00239—Ceramics or ceramic-like structures based on metal oxides containing zirconia or zirconium oxide ZrO2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00389—The prosthesis being coated or covered with a particular material
- A61F2310/00592—Coating or prosthesis-covering structure made of ceramics or of ceramic-like compounds
- A61F2310/00796—Coating or prosthesis-covering structure made of a phosphorus-containing compound, e.g. hydroxy(l)apatite
Abstract
An intervertebral prosthetic device (10, 76) for replacement of an intervertrebral disc includes a first fixation member (14, 78) for fixation within a first vertebral body (20) and a second fixation member (16, 80) for fixation within a second vertebral body (22) adjacent the first vertebral body (20).
The present prosthetic device (10, 76) also includes a compressible member (18, 82) for positioning between the first (14, 78) and second (16, 80) fixation members. The compressible member (18, 82) has an outer periphery less than or substantially equal to a diameter of a nucleus pulposus of the intervertebral disc. The compressible member (18, 82) thus essentially fits within the annulus fibrosis of the intervertebral disc. The compressible member (18, 82) also has at least one spring (40, 54, 58, 62) that can be pre-loaded to place the annulus fibrosis under tension and to reproduce the mechanical properties of a natural disc.
The present prosthetic device (10, 76) also includes a compressible member (18, 82) for positioning between the first (14, 78) and second (16, 80) fixation members. The compressible member (18, 82) has an outer periphery less than or substantially equal to a diameter of a nucleus pulposus of the intervertebral disc. The compressible member (18, 82) thus essentially fits within the annulus fibrosis of the intervertebral disc. The compressible member (18, 82) also has at least one spring (40, 54, 58, 62) that can be pre-loaded to place the annulus fibrosis under tension and to reproduce the mechanical properties of a natural disc.
Description
wo ~sr~e . reTi~s9~nme INTER~~ERTEBRAL PROST~IETIC DEVTCE
This invention relates to a novel intervertebral prosthetic device. More particularly, this invention relates to an intervertebral prosthetic device that can be implanted to replace a damaged intervertasbral disc.
The human spine is a flexible structure comprised of thirty-three vertebrae. Intervertebral discs separate and cushion adjacent vertebrae. Ths intervertebral discs act as shock absorbers and allow bending between the vertebrae.
An intervertebral disc comprises two major components: the nucleus pulposus and the annulus fibrosis. The nucleus pulposus is centrally located in the disc and occupies 25-40% of the disc's total cross sectional area. The nucleus pulposus usually contains 70-90% water by weight and mechanically functions like an incompressible hydrostatic material. The annulus fibrosis surrounds the nucleus pulposus and resists torsional and bending forces applied to the disc. The annulus fibrosis thus serves as the disc's main stabilizing structure. Vertebral end-plates separate the disc from the vertebral bodies on either side of the disc.
Individuals with damaged or degenerated discs often experience significant pain. They pain results in part from instability in the intervertebral joint due to a _ WO 98122050 PCTlU5S97119610 loss of hydrostatic pressure in the nucleus pulposus.
Loss of hydrostatic pressure leads to a loss of disc height.
A conventional treatment for degenerative disc disease is spinal fusion. In one such surgical procedure, a surgeon removes the damaged natural disc and then fuses the two adjacent vertebral bones into one piece. The surgeon fuses the vertebral bones by grafting bone between the adjacent vertebrae and sometimes uses metal rods, cages, or screws to hold the graft in place until the graft heals. Other fusion procedures do not require surgical removal of the disc.
Although spinal fusion may alleviate pain associated with degenerative disc disease, it also results in loss of motion at the fused vertebral joint. Lack of motion at the fused site puts additional pressure on the discs above and below the fusion, sometimes causing them to degenerate and produce pain. To remedy the problems associated with spinal fusion, prosthetic devices were developed to replace the damaged disc with a suitable biomechanical equivalent.
- Existing prosthetic devices have met with limited success in reproducing the biomechanics of a natural disc. For example, U.S. Patent No. 4,759,769 to Hedman et. 81. discloses a synthetic disc having upper and lower plates hinged together. Although the hinged disc allows forward bending between adjacent vertebras, the hinged disc does not allow axial compression or lateral flexion.
Nor does it allow axial rotation of the vertebral column at the site of the implant. Therefore, the Hedman et.
a1. device lacks the biomechanics of a natural disc.
Likewise, the prosthetic disc device disclosed in U.S. Patent No. 4,309,777 to Patil does not replicate natural motion between adjacent discs. The Patil device includes two cups, one overlapping the other and spaced from t:~e other by springs. The cups move only in a single axial dimension. The Patil device thus does not WA 98/220 PCT/U897/19610 . .
-3~
enable natural flexion of the spine in any direction.
In addition, the, highly constrained motion of the Patil device can lead to high deviceitissue interface stresses and implant loosening.
Many synthetic disc devices connect to the vertebral bodies by conventional mechanical attachments, such as pegs or screws, which are known to loosen under cyclic loading conditions. Other synthetic disc devices use plastic or elastomeric components which, over a lifetime, l0 produce debris from wear and possible unknown side ef facts .
The problems suggested in the preceding are not intended to be exhaustive but rather are among many which tend to reduce the effectiveness of known intervertebral prosthetic devices. Other noteworthy problems may also exist; however, those presented above should be sufficient to demonstrate that currently known devices are amenable to worthwhile improvement.
Accordingly, it is a general abject of the invention to provide an intervertebral disc prosthetic and method for implanting the same which will obviate or minimize difficulties of the type previously described.
More particularly, it is a specific object of the invention to provide an intervertebral prosthetic device which replicates the mechanical properties of a natural intervertebral disc.
It is another object of the invention to provide an intervertebral prosthetic device which restores disc height, defined as the axial distance between vertebrae adj scent the damaged disc, and which duplicates the range of motion of a natural intervertebral joint.
It is still another object of the invention to provide an intervertebral prosthetic device which may be implanted and maintained in stable relation to WO 9~/23A30 PCT/I1897/19610 .
-4~
adjacent vertebrae without conventional mechanical attachments.
It is a further object of the invention to provide an intervertebral disc prosthesis which suffers minimal degradation of the prosthetic material and which produces minimal wear debris under long-term cyclic loading conditions.
It is yet a further object of the invention to provide an intervertebral prosthetic device which axially compresses and thus dissipates energy, may be easily repaired or replaced, may be easily manufactured and utilized by a surgeon, and is durable and modular.
It is yet another object of the invention to provide a method of implanting an intervertebral prosthetic device which stabilizes an operative intervertebral joint and restores the mechanical properties of a degenerated disc.
These objectives are achieved by an intervertebral prosthetic device having a first fixation member, a second fixation member, and a compressible member disposed between them. The first fixation member is - implanted within a first vertebral body, and the second fixation member is implanted within a second vertebral body adjacent the first vertebral body.
The first fixation member generally comprises an adjustable member and a support member. The adjustable member preferably has a first plate, a second plate, and at least one adjustment element that extends between the two plates and enables adjustment of the height of the adjustable member along its longitudinal axis. The first plate is operably positioned against subchondral bone of a distant end-plate of the f first vertebral body, and the second plate is operably positioned against the support member.
The second fixation member may include both a support member and an adjustable member or, in an alternative embodiment, may include only a support w~ ~o rc~smii~sio -5~
member. In the first embodiment; the adjustable member is structurally similar to the adjuetabl~ member of the first fixation member and includes a first plate for positioning against subchondral bone of a distant end-s plate of the second vertebral body, a second plate for ' positioning against the support somber, and at least one adjustment element extending between the two plates.
In the second embodiment, the support member is operably positioned against a near end-plate of the second vertebral body.
One of skill in the art will recognize that, like the second fixation member, the first fixation member may comprise only a support member, depending on the patient's needs. Moreover, the support members are modular. The support members are generally wedge-shaped and may be made in difference sizes to accommodate the angle between adjacent vertebrae at a specific vertebral level. The angle between adjacent vertebrae typically ranges between 3-10 degrees, and, thus the angle created by opposing surfaces of the wedge-shaped support member falls within that same range.
' The compressible member has an outer periphery less than or substantially equal to the diameter of the nucleus pulposus of the operative intervertebral disc.
In other words, the compre~ssib3e member is sized to replace the nucleus pulposus of an intervertebral disc and essentially to fit within the annulus fibrosis of the intervertebral disc. The compressible member comprises at least one spring that can be pre-stressed or pre-loaded to place the annulus fibrosis under tension and to reproduce the mechanical properties of a natural disc: Maintaining the annulus fibrosis under tension results in an artificial intervertebral joint that is stable.
' 35 The fixation members include a porous surface suitable for bone ingrowth so that the fixation members i wo 9sn~.oso rcT~s~nri~zo -s=
fuse to the vertebrae without requiring conventional mechanical attachments.
Additional objects and advantages of the invention are set forth in the description which follows, and in part will be obvious from the de~cription, or may be learned by practice of the invention: The objects and ' advantages of the invention may be realized and obtained by means of the instrumentalities and combinations particularly pointed out in the specification and the appended claims.
The accompanying drawings, which are incorporated in and constitute a part of the specif ication, illustrate a presently preferred embodiment of the invention, and, together with the general description given above and the detailed description of the preferred embodiment given below, serve to explain the principles of the invention.
Figure 1 is a schematic, cut-away, side view of an - 20 intervertebral prosthetic device implanted in a spine in accordance with a preferred embodiment of the invention;
Figure 2 is a top perspective view of a compressible member of the subject intervertebral prosthetic device;
Figures 3A-3C are top perspective views of different embodiments of a spring of the compressible member of the subject intervertebral prosthetic device;
Figure 4 is a top perspective, partially exploded view of a fixation member of the subject intervertebral prosthetic device and shows an adjustable member and a support member;
Figure 5 is a top view of a second plate of the adjustable member;
Figure 6 is a side view, in cross-section; of the support member;
VSO 98122030 PCT1U89711961fl Figure ? is a sahamatic, cut-away, sidm view of an intervertebral prosthetic device implanted in a spine in accordance with another preferred embodi~tent of the invention;
Figure 8 is a schematic, cut-away, side view showing subchondral bones of a superior vertebral body after a partial vertebrectomy;
Figure 9 is a sectional view of a vertebrae after a partial vertebrectomy, as taken along line 9-9 of io Figure 8;
Figure to is a schematic, cut-away, side view of a vertebral joint area after a partial vertebrectomy and excision of a nucleus pulposus of a natural disc;
Figure 11 is a schematic, cut-away, side view of a vertebral j oint and shows a f fixation member, including an adjustable member and a support member, implanted in an inferior vertebral body;
Figure 12 is a schematic, cut-away, side view of a vertebral joint and shows a compressible member 2o implanted in an intervertebral joint;
Figure 13 is a schematic, cut-away, side view of a vertebral joint and shows a technique for adjusting the height of an adjustable member implanted in a superior vertebral body; and Figure 14 is a schematic, cut-away, side view of a vertebral joint and shows a technique for bone grafting an adjustable member in a superior vertebral body:
Referri~ now to the drawings, wherein like numerals indicate like parts, and initially to Figure 1, there will be seen an intervertebral prosthetic device, generally indicated 10, implanted in a spine 12 in accordance with a preferred embodiment of the present invention: The intervertebral prosthetic device 10 is designed to replace a damaged natural disc. The WO 98122050 PCTlt3S97/1961~
-8-_ intervertebral prosthetic device 10 has a first fixation member 14, a second fixation member 16, and a compressible member 18 that is positioned between the f first f fixation member 14 and the second f fixation member 16.
The first f fixation member 14 is positioned in a first vertebral body 20, and the second fixation member 16 is positioned within a second vertebral body 22 adjacent the first vertebral body 20. Each fixation member 14 and 16 has an adjustable member 28 and 30, respectively, and a support member 32 and 34, respectively. Each fixation member also has a bone-contacting surface, preferably porous, for positioning against subchondral bone of an associated vertebral body.
In Figure l, a bone-contacting surface 27 of the adjustable member 28 is positioned against the subchondral bone of an end-plate 36 of the superior vertebral body 20, and a bone-contacting surface 29 of the adjustable member 30 is positioned against the subchondral bone of an end-plate 38 of the inferior vertebral body 22. As will be described below, the - present intervertebral prosthetic device does not require conventional mechanical attachments, such as Begs or screws, to hold the prosthetic device in place. The intravertebral (i.e., within a vertebral body) positioning of the fixation members maintains the prosthetic device in stable relationship at the operative - intervertebral joint.
The adjustable member 28 of the first fixation member 14 has an imaginary first longitudinal axis, shown by dashed line A-A, and adjustment elements 24 that allow adjustment of the height of the adjustable member 28 substantially along its longitudinal axis A-A. In the embodiment shown in Figure 1, the second fixation member 16 is structurally similar to the first fixation member 14, but inverted. The adjustable member 30 of the second fixation member 16 has a second longitudinal axis, shown WO 90 PCT/U519"lA19610 -by dashd lin0 8-B, and adjustment elements ~6 that allow adjustment of the height of the adjustable member 30 substantially along its longitudinal axis B-8.
The eospressible member 18 comprises at least one spring and, in a preferred embodiment, comprises a plurality of springs 40. One skilled in the art, howe~rar, will recognize that the compressible member may comprise other suitable configurations. For example, the compressible member may comprise a monolithic body made of an biocompatible material compressible in an axial direction, that is, a direction substantially parallel to the spine.
The compressible member i8 is implanted in the region of an excavated nucleus pulposus of the operative intervertebral disc. The compressible member 18 is dimensioned so that the annulus fibrosis of the natural disc is maintained. The present intervertebral prosthetic device restores the mechanical properties of the nucleus pulposus without disrupting the annulus fibrosis. Retention of the annulus fibrosis maintains stability of the intervertebral joint at the implant - site. In addition, the annulus fibrosis serves as a boundary for the compressible member and minimizes accidental dislodgement of the prosthetic device.
Significantly, the intervertebral prosthetic device 10 permits at least four degrees of relative motion between the first vertebral body 20 and the second vertebral body 22. These degrees of relative motion include sagittal bending, coronal bending, axial rotation, and axial compression. Moreover, the compressible member permits small increments of translational movement between the vertebral bodies ( i . e. , fifth and sixth degrees of relative motion, namely anterior-posterior translation and side-to-side, or lateral, translation).
A pref0rred embodiment of the compressible member 18 is shown in Figure 2. The compressible member 18 has prp 9gn2psp PCT!(JS97119610 a top plate 42, a bottom plate 44, and a plurality of coil springs 40 extending between the top plate 42 and the bottom plate 44. The top plate 42 has a first surface 46, which is connectable to the first fixation member 14, and a second surface 48. The bottom plate 44 also has a first surface 50, which is connectable to the second fixation member 16, and a second surface 52.
The springs 40 extend between the second surfaces 48 and 52.
When pre-loaded, as will be explained in more detail below, the compressible member 18 preferably has an axial height of approximately 1.5 cm, greatest at the L45 vertebral level and slightly less at the upper lumbar vertebrae. The coil springs 40 are preferably designed to have non-linear stiffness so that they become stiffer at higher applied loads. The nonlinear stiffness simulates physiological intervertebral stiffness.
One skilled in the art will recognize other embodiments contemplated by the present invention. For example, the comprsssible member 18 may comprise a plurality of springs extending between, and directly - connected to, support members 32 and 34. Alternatively, the compressible member 18 may comprise a single spring with a relatively large coil diameter (not shown) extending between, and directly connected to, the support members 32 and 34. Any spring arrangement may be utilized that achieves sufficient axial compressive force to replicate the biomechanics of the natural disc.
In each embodiment, the compressible member includes an imaginary longitudinal axis, shown by the dashed line C-C in Figure 2, and an outer periphery in a plane transverse to the longitudinal axis C-C. A largest dimension of the compressible members outer periphery is less than or substantially egual to the diameter of a nucleus pulposus of the natural intervertebral disc.
Put another way, the annulus fibrosis of the natural disc, which is substantially preserved in the WO X50 PCTfUS9?fI~6i8 .
-lI=
implantation procedure, circumscribes the compressible member i8. For example, where the compressible member comprises a plurality of springs, the outer periphery ' of the compressible member circumscribes the springs, and the largest dimension of that outer periphery may extend to, but does not extend beyond, the nucleus pulposus. In other embodiment, where the compressible member includes a top plate and a bottom plate, and where those plates fit within the annulus fibrosis and extend beyond the outermost portions of the springs, the outer periphery equals the larger of the two plate peripheries.
In quantitative terms, the outer periphery of the . compressible member preferably ranges between 2.0 cm to 3.0 cm, which approximates the diameter of the nucleus pulposus of a natural intervertebral disc.
Figures 3A-3C show three embodiments of a coil spring designed to possess non-linear stiffness. In the embodiment of Figure 3A, the coil spring 54 has a variable, or non-uniform, cross-sectional diameter 56.
Figure 3B shows another embodiment in which a coil spring 58 has a variable pitch 60, where the pitch is defined ' as the distance between successive coils of the spring 58. Figure 3C shows a third embodiment of a coil spring 62 in which at least two of the spring coils have different radii 64 measured from an imaginary axis D-D
extending along the central axis of the spring 62.
Figure 4 shows a preferred embodiment of the first fixation member 14. In the embodiment shown in Figure 1, the second fixation member 1~ is structurally similar to the first fixation member 14, but inverted. The following discussion thus also applies to the second fixation member 16.
The fixation member Z4 comprises an adjustable member , genera l ly indicated 2 8 , and a support member 3 2 .
The adjustable member 28 is adjustable in an axial direction by adjustment elements 24. The adjustment elements 24 preferably comprise telescopic struts a WO 901Z?,05(1 PCTlU897Ii9610 _ extending between a first plate 31 and a second plate 33. In a preferred embodiment, the first plate 31 has a bone-contacting surface, such as 27 shown in an operative context in Figure 1, and the second plate has a surface 35 for positioning against the support member 32. Although the illustrative embodiment shows flat ' plates 31 and 33, it will be understood by those skilled in the art that these structures need not be flat and may, for example, have undulating surfaces. In fact, in one embodiment, the bone-contacting surface 27 of the first plate 31 is concave to match the contour of the subchondral bone of the associated vertebral body.
The adjustment elements 24 adjust the distance between the f first bone-contacting plate 31 and the second plate 33, thus adjusting the height of the adjustable member 28. A surgeon may adjust the telescopic struts to increase the height of the adjustable member and thus pre-load the compressible member to mechanically reproduce the axial compression absorbed by a nucleus pulposus of a natural disc. Pre-loading the compressible member restores the intervertebral height at the - operative joint and restores the function of the annulus fibrosis. The annulus fibrosis load shares with the compressible member which reduces implant/tissue interface stresses.
Each telescopic strut is provided with a lock screw 63 to adjust the length of the strut 24 and hence control the height of the adjustable member. The lock screw 63 may comprise, for example, a pin (not shown) that extends through both the telescoping portion 65 and the housing portion 67 of the strut 24. Each strut 24 is independently adjustable. Figure 5 shows a top view of the second plate 33 of the adjustable member 28. The -ad justment elements 24 preferably are spaced equidistant from each other to enable specific height adjustment of various regions of the adjustable member.
wo ~sn~so rc°r.~s~rro A key feature of the present invention is that controlling the height of the adjustable membe~cs 28 and 30, along with :electing an appropriately-sized support member, controls the "disc" height. The diec height is defined as the axial distance between the vertebrae above and below the operative disc. In addition to restoring the disc height, the compressible member 18 acts as a shock absorber to minimize impact loading and, thus, minimize device failure or vertebral fracture.
In a preferred embodiment, the first and second fixation members 14 and 16 have porous portions, such as the bone-contacting surface 27, to permit bone ingrowth. In another embodiment, a biocompatible fabric or suitable material may be wrapped around the f fixation members to enable bone ingrowth. The pre8ent prosthetic device does not require conventional mechanical attachments, such as pegs or screws, to hold the prosthesis permanently in place. The present prosthetic device, however, may include mechanical or other attachments to supplement the porous portions of the fixation members and to temporarily fix the prosthetic device in place until bone ingrowth has occurred.
To further promote bone ingrowth, the adjustment elements 24 may include fins 66 extending outward from an exterior surface of the element 24, as shown in Figure 4 . The f ins 66 increase the surface area of the fixation member 14 to which bone may attach. Preferably, these fins 66 ate located on the adjustment elements that are positioned on the anterior side of the adjustable member 28. The present prosthetic device also may include protuberances (not shown) on the bone-contacting surface of the adjustable members to increase the surface area of the porous portion of the fixation members and, thus, encourage bone ingrowth.
Figure 6 shows a cross-section of support member 32. The support member 32 has a first surface 72 that operably faces away from the compressible member 18 and W0 9A8/~030 PCT/I199'1/196H1 -ly-a second surface 74 that operably faces towards the compressible member 18. The first and second surfaces 72 and 74 are oblique so that a circumferential surface 77 around the support member 32 varies in width, as shown in Figure 4. The support member 32 thus is wedge-shaped.
In other words , the support member 3 2 preferably tapers from a maximum thickness at one side 73 to a minimum thickness at an opposite side 75. Generally, the support member 32 is thicker on the side of the fixation member 14 placed anteriorly in a patient ~ s spine to account for the spines natural curvature.
The support members are constructed with various thicknesses and with various angled surfaces, depending upon the vertebral level of the operative intervertebral joint. An angle a shown in Figure 6 ranges between 3-l0 degrees. The support members are shaped to maintain sagittal alignment. Maintaining sagittal alignment avoids nonuniform loading of the compressible member and avoids early fatigue failure of that member.
Figure 7 shows another embodiment of the present intervertebral prosthetic device, generally indicated 7 6 , which comprises a f first fixation member 78 , a second fixation member 80, and a compressible member 82. The compressible member 82 is positioned between the first and second fixation members 78 and 80. The second fixation member comprises a wedge-shaped support member with an upper surface 84 that attaches to the compressible member 82 and a lower surface 86 that rests upon subchondral bone of a near end-plate 88 of an inferior vertebral body. In this embodiment, adjustment of the first fixation member 78 pre-loads the compressible member 82 to an appropriate extent. This embodiment is particularly suited for young patients.
Also, in this embodiment, a lower surface 86 of the support member 80 has a slightly convex shape to match the natural contour of the near end-plate of the inferior W0 X22030 PCT/US97l1lb~A ..
vertebral body. The surface 86 is preferably composed of a porous material.
As evident from the embodiments of Figures 1 and 7, the present intervertebral prosthetic device has a modular design so that the prosthesis may be sized to the patient's anatomy and designed for the patient's condition. The modular design also enables replacement of individual comgonents of the prosthesis (i.e., an adjustable member, a support member, or a compressible member), rather than replacement of the entire prosthesis should one component fail. The compressible member is preferably attached to the fixation members by mechanical attachments, such screws, rather than bone cement so that a surgeon may easily replace damaged or worn components.
25 Moreover, because the present prosthetic device has no ball bearings, rollers, or hinges, it produces little wear debris. And, because the present prosthetic device need not include plastic polymers or elastomeric components, the present prosthetic device does not degrade under long-term cyclic loading conditions.
The present prosthetic device comprises biocompatible metallic materials, preferably a titanium alloy having, for example, 4% vanadium and 6% aluminum.
. Persons of skill in the art will recognize other suitable materials, for example, a cobalt-chromium alloy, such as alloy number 301. Alternatively, the present prosthetic device, with the exception of the springs of the compressible member, may comprise a ceramic material, such as aluminium oxide and zirconium oxide. The porous surfaces of the bone-contacting member and support member may be coated with hydroxyapatite or bioactive proteins (e. g., bone morphcx~enic protein) to encourage bone ingrowth.
A method of intervert~bral disc replaceaent now will be described in connection with Figures 8-14. Figure 8 shows a pathological intervertebral disc 90 located between a superior vertebral body 92 and an inferior vertebral body 94. Prior to implantation, a surgeon performs a partial vertebrectomy to excise bone matter from the superior vertebral body 92 for receipt of a fixation member. The partial vertebrectomy creates a cavity bounded by subchondral bone of a distant end-plate 96 and subchondral bone of a near end-plate 98 of the superior vertebral body 92. Figure 9 shows a cross sectional view of the superior vertebral body 92 after the partial vertabrectony, as taken along line 9-9 in Figure 8.
The surgeon next excises the nucleus pulposus of the damaged disc to create a cavity 100, as shown in Figure 10, for receipt of the compressible member. The annulus fibrosis 102, seen in Figure 11, is maintained.
The surgeon may perform a partial vertebrectomy on the inferior vertebral body or may excise cartilage matter only to the near end-plate, depending upon whether the surgeon implants the embodiment shown in Figure 1 or the embodiment shown in Figure 7, respectively. The 2o following description details implantation of the prosthesis .shown in Figure 1; however, one of skill in ' the art would understand how to modify the procedure described below to implant the prosthesis of Figure 7.
Upon completion of the partial vertebrectomies, the surgeon implants a fixation member 104 into the inferior vertebral body 94, as shown in Figure 11. The surgeon selects a support member with an appropriate thickness to accommodate the angulation at the operative intervertebral levels. The surgeon then inserts a compressible member 106 into the cavity formerly containing the nucleus pulposus of the damaged disc and connects it to the fixation member 104, as shown in Figure 12 . The compressible member 106 and the f fixation member 104 nay be connected by conventional attachment members, such as screws, or by biocompatible cement or a suitable adhesive composition. Finally, the surgeon i~aplants another fixation member, similar to the one wo 9sn~oso rc~rn~rs9~i:mo _ -17~
implanted in the inferior vertebral body 94, yet inverted, in the superior vertebral body 92. Connection of that fixation member to the compressible member 106 forms an intervertebral prosthetic device like the one shown in Figure 1.
once the fixation menbsrs are in plat~, the surgeon expands each adjustable member, one at a tile, by placing a spreader device with a calibrated tensiometer between the first and second plates of the adjustable member.
The surgeon applies distraction until the adjustable member is seated against the subchondral bone of the vertebral body and until the desired compression has been applied to the compressible member. The adjustment elements of the adjustable member are then secured.
Figure 13 shows rotation of the lock screws 112 of individual telescopic struts 108 to secure the struts at an appropriate height.
The surgeon next packs cancellous bone grafts 118 around the struts of each adjustable member, as shown in Figure 14. The growth of bone around the fixation member and into its porous surfaces secures the intervertebrai prosthetic device in place, absent mechanical attachments typically used in conventional disc prostheses. The surgeon then replaces the cortical bone from the partial vertebrectomy procedure and secures it with a bone screw or bone cement.
Additional advantages and modifications will readily occur to those skilled in the art. Therefore, the invention in ita broader aspects is not limited to the specific details, and representative devices, shown and described herein. Accordingly, various modifications may be made without departing from the spirit or scope of the general inventive concept as defined by the appended claims and their equivalents.
This invention relates to a novel intervertebral prosthetic device. More particularly, this invention relates to an intervertebral prosthetic device that can be implanted to replace a damaged intervertasbral disc.
The human spine is a flexible structure comprised of thirty-three vertebrae. Intervertebral discs separate and cushion adjacent vertebrae. Ths intervertebral discs act as shock absorbers and allow bending between the vertebrae.
An intervertebral disc comprises two major components: the nucleus pulposus and the annulus fibrosis. The nucleus pulposus is centrally located in the disc and occupies 25-40% of the disc's total cross sectional area. The nucleus pulposus usually contains 70-90% water by weight and mechanically functions like an incompressible hydrostatic material. The annulus fibrosis surrounds the nucleus pulposus and resists torsional and bending forces applied to the disc. The annulus fibrosis thus serves as the disc's main stabilizing structure. Vertebral end-plates separate the disc from the vertebral bodies on either side of the disc.
Individuals with damaged or degenerated discs often experience significant pain. They pain results in part from instability in the intervertebral joint due to a _ WO 98122050 PCTlU5S97119610 loss of hydrostatic pressure in the nucleus pulposus.
Loss of hydrostatic pressure leads to a loss of disc height.
A conventional treatment for degenerative disc disease is spinal fusion. In one such surgical procedure, a surgeon removes the damaged natural disc and then fuses the two adjacent vertebral bones into one piece. The surgeon fuses the vertebral bones by grafting bone between the adjacent vertebrae and sometimes uses metal rods, cages, or screws to hold the graft in place until the graft heals. Other fusion procedures do not require surgical removal of the disc.
Although spinal fusion may alleviate pain associated with degenerative disc disease, it also results in loss of motion at the fused vertebral joint. Lack of motion at the fused site puts additional pressure on the discs above and below the fusion, sometimes causing them to degenerate and produce pain. To remedy the problems associated with spinal fusion, prosthetic devices were developed to replace the damaged disc with a suitable biomechanical equivalent.
- Existing prosthetic devices have met with limited success in reproducing the biomechanics of a natural disc. For example, U.S. Patent No. 4,759,769 to Hedman et. 81. discloses a synthetic disc having upper and lower plates hinged together. Although the hinged disc allows forward bending between adjacent vertebras, the hinged disc does not allow axial compression or lateral flexion.
Nor does it allow axial rotation of the vertebral column at the site of the implant. Therefore, the Hedman et.
a1. device lacks the biomechanics of a natural disc.
Likewise, the prosthetic disc device disclosed in U.S. Patent No. 4,309,777 to Patil does not replicate natural motion between adjacent discs. The Patil device includes two cups, one overlapping the other and spaced from t:~e other by springs. The cups move only in a single axial dimension. The Patil device thus does not WA 98/220 PCT/U897/19610 . .
-3~
enable natural flexion of the spine in any direction.
In addition, the, highly constrained motion of the Patil device can lead to high deviceitissue interface stresses and implant loosening.
Many synthetic disc devices connect to the vertebral bodies by conventional mechanical attachments, such as pegs or screws, which are known to loosen under cyclic loading conditions. Other synthetic disc devices use plastic or elastomeric components which, over a lifetime, l0 produce debris from wear and possible unknown side ef facts .
The problems suggested in the preceding are not intended to be exhaustive but rather are among many which tend to reduce the effectiveness of known intervertebral prosthetic devices. Other noteworthy problems may also exist; however, those presented above should be sufficient to demonstrate that currently known devices are amenable to worthwhile improvement.
Accordingly, it is a general abject of the invention to provide an intervertebral disc prosthetic and method for implanting the same which will obviate or minimize difficulties of the type previously described.
More particularly, it is a specific object of the invention to provide an intervertebral prosthetic device which replicates the mechanical properties of a natural intervertebral disc.
It is another object of the invention to provide an intervertebral prosthetic device which restores disc height, defined as the axial distance between vertebrae adj scent the damaged disc, and which duplicates the range of motion of a natural intervertebral joint.
It is still another object of the invention to provide an intervertebral prosthetic device which may be implanted and maintained in stable relation to WO 9~/23A30 PCT/I1897/19610 .
-4~
adjacent vertebrae without conventional mechanical attachments.
It is a further object of the invention to provide an intervertebral disc prosthesis which suffers minimal degradation of the prosthetic material and which produces minimal wear debris under long-term cyclic loading conditions.
It is yet a further object of the invention to provide an intervertebral prosthetic device which axially compresses and thus dissipates energy, may be easily repaired or replaced, may be easily manufactured and utilized by a surgeon, and is durable and modular.
It is yet another object of the invention to provide a method of implanting an intervertebral prosthetic device which stabilizes an operative intervertebral joint and restores the mechanical properties of a degenerated disc.
These objectives are achieved by an intervertebral prosthetic device having a first fixation member, a second fixation member, and a compressible member disposed between them. The first fixation member is - implanted within a first vertebral body, and the second fixation member is implanted within a second vertebral body adjacent the first vertebral body.
The first fixation member generally comprises an adjustable member and a support member. The adjustable member preferably has a first plate, a second plate, and at least one adjustment element that extends between the two plates and enables adjustment of the height of the adjustable member along its longitudinal axis. The first plate is operably positioned against subchondral bone of a distant end-plate of the f first vertebral body, and the second plate is operably positioned against the support member.
The second fixation member may include both a support member and an adjustable member or, in an alternative embodiment, may include only a support w~ ~o rc~smii~sio -5~
member. In the first embodiment; the adjustable member is structurally similar to the adjuetabl~ member of the first fixation member and includes a first plate for positioning against subchondral bone of a distant end-s plate of the second vertebral body, a second plate for ' positioning against the support somber, and at least one adjustment element extending between the two plates.
In the second embodiment, the support member is operably positioned against a near end-plate of the second vertebral body.
One of skill in the art will recognize that, like the second fixation member, the first fixation member may comprise only a support member, depending on the patient's needs. Moreover, the support members are modular. The support members are generally wedge-shaped and may be made in difference sizes to accommodate the angle between adjacent vertebrae at a specific vertebral level. The angle between adjacent vertebrae typically ranges between 3-10 degrees, and, thus the angle created by opposing surfaces of the wedge-shaped support member falls within that same range.
' The compressible member has an outer periphery less than or substantially equal to the diameter of the nucleus pulposus of the operative intervertebral disc.
In other words, the compre~ssib3e member is sized to replace the nucleus pulposus of an intervertebral disc and essentially to fit within the annulus fibrosis of the intervertebral disc. The compressible member comprises at least one spring that can be pre-stressed or pre-loaded to place the annulus fibrosis under tension and to reproduce the mechanical properties of a natural disc: Maintaining the annulus fibrosis under tension results in an artificial intervertebral joint that is stable.
' 35 The fixation members include a porous surface suitable for bone ingrowth so that the fixation members i wo 9sn~.oso rcT~s~nri~zo -s=
fuse to the vertebrae without requiring conventional mechanical attachments.
Additional objects and advantages of the invention are set forth in the description which follows, and in part will be obvious from the de~cription, or may be learned by practice of the invention: The objects and ' advantages of the invention may be realized and obtained by means of the instrumentalities and combinations particularly pointed out in the specification and the appended claims.
The accompanying drawings, which are incorporated in and constitute a part of the specif ication, illustrate a presently preferred embodiment of the invention, and, together with the general description given above and the detailed description of the preferred embodiment given below, serve to explain the principles of the invention.
Figure 1 is a schematic, cut-away, side view of an - 20 intervertebral prosthetic device implanted in a spine in accordance with a preferred embodiment of the invention;
Figure 2 is a top perspective view of a compressible member of the subject intervertebral prosthetic device;
Figures 3A-3C are top perspective views of different embodiments of a spring of the compressible member of the subject intervertebral prosthetic device;
Figure 4 is a top perspective, partially exploded view of a fixation member of the subject intervertebral prosthetic device and shows an adjustable member and a support member;
Figure 5 is a top view of a second plate of the adjustable member;
Figure 6 is a side view, in cross-section; of the support member;
VSO 98122030 PCT1U89711961fl Figure ? is a sahamatic, cut-away, sidm view of an intervertebral prosthetic device implanted in a spine in accordance with another preferred embodi~tent of the invention;
Figure 8 is a schematic, cut-away, side view showing subchondral bones of a superior vertebral body after a partial vertebrectomy;
Figure 9 is a sectional view of a vertebrae after a partial vertebrectomy, as taken along line 9-9 of io Figure 8;
Figure to is a schematic, cut-away, side view of a vertebral joint area after a partial vertebrectomy and excision of a nucleus pulposus of a natural disc;
Figure 11 is a schematic, cut-away, side view of a vertebral j oint and shows a f fixation member, including an adjustable member and a support member, implanted in an inferior vertebral body;
Figure 12 is a schematic, cut-away, side view of a vertebral joint and shows a compressible member 2o implanted in an intervertebral joint;
Figure 13 is a schematic, cut-away, side view of a vertebral joint and shows a technique for adjusting the height of an adjustable member implanted in a superior vertebral body; and Figure 14 is a schematic, cut-away, side view of a vertebral joint and shows a technique for bone grafting an adjustable member in a superior vertebral body:
Referri~ now to the drawings, wherein like numerals indicate like parts, and initially to Figure 1, there will be seen an intervertebral prosthetic device, generally indicated 10, implanted in a spine 12 in accordance with a preferred embodiment of the present invention: The intervertebral prosthetic device 10 is designed to replace a damaged natural disc. The WO 98122050 PCTlt3S97/1961~
-8-_ intervertebral prosthetic device 10 has a first fixation member 14, a second fixation member 16, and a compressible member 18 that is positioned between the f first f fixation member 14 and the second f fixation member 16.
The first f fixation member 14 is positioned in a first vertebral body 20, and the second fixation member 16 is positioned within a second vertebral body 22 adjacent the first vertebral body 20. Each fixation member 14 and 16 has an adjustable member 28 and 30, respectively, and a support member 32 and 34, respectively. Each fixation member also has a bone-contacting surface, preferably porous, for positioning against subchondral bone of an associated vertebral body.
In Figure l, a bone-contacting surface 27 of the adjustable member 28 is positioned against the subchondral bone of an end-plate 36 of the superior vertebral body 20, and a bone-contacting surface 29 of the adjustable member 30 is positioned against the subchondral bone of an end-plate 38 of the inferior vertebral body 22. As will be described below, the - present intervertebral prosthetic device does not require conventional mechanical attachments, such as Begs or screws, to hold the prosthetic device in place. The intravertebral (i.e., within a vertebral body) positioning of the fixation members maintains the prosthetic device in stable relationship at the operative - intervertebral joint.
The adjustable member 28 of the first fixation member 14 has an imaginary first longitudinal axis, shown by dashed line A-A, and adjustment elements 24 that allow adjustment of the height of the adjustable member 28 substantially along its longitudinal axis A-A. In the embodiment shown in Figure 1, the second fixation member 16 is structurally similar to the first fixation member 14, but inverted. The adjustable member 30 of the second fixation member 16 has a second longitudinal axis, shown WO 90 PCT/U519"lA19610 -by dashd lin0 8-B, and adjustment elements ~6 that allow adjustment of the height of the adjustable member 30 substantially along its longitudinal axis B-8.
The eospressible member 18 comprises at least one spring and, in a preferred embodiment, comprises a plurality of springs 40. One skilled in the art, howe~rar, will recognize that the compressible member may comprise other suitable configurations. For example, the compressible member may comprise a monolithic body made of an biocompatible material compressible in an axial direction, that is, a direction substantially parallel to the spine.
The compressible member i8 is implanted in the region of an excavated nucleus pulposus of the operative intervertebral disc. The compressible member 18 is dimensioned so that the annulus fibrosis of the natural disc is maintained. The present intervertebral prosthetic device restores the mechanical properties of the nucleus pulposus without disrupting the annulus fibrosis. Retention of the annulus fibrosis maintains stability of the intervertebral joint at the implant - site. In addition, the annulus fibrosis serves as a boundary for the compressible member and minimizes accidental dislodgement of the prosthetic device.
Significantly, the intervertebral prosthetic device 10 permits at least four degrees of relative motion between the first vertebral body 20 and the second vertebral body 22. These degrees of relative motion include sagittal bending, coronal bending, axial rotation, and axial compression. Moreover, the compressible member permits small increments of translational movement between the vertebral bodies ( i . e. , fifth and sixth degrees of relative motion, namely anterior-posterior translation and side-to-side, or lateral, translation).
A pref0rred embodiment of the compressible member 18 is shown in Figure 2. The compressible member 18 has prp 9gn2psp PCT!(JS97119610 a top plate 42, a bottom plate 44, and a plurality of coil springs 40 extending between the top plate 42 and the bottom plate 44. The top plate 42 has a first surface 46, which is connectable to the first fixation member 14, and a second surface 48. The bottom plate 44 also has a first surface 50, which is connectable to the second fixation member 16, and a second surface 52.
The springs 40 extend between the second surfaces 48 and 52.
When pre-loaded, as will be explained in more detail below, the compressible member 18 preferably has an axial height of approximately 1.5 cm, greatest at the L45 vertebral level and slightly less at the upper lumbar vertebrae. The coil springs 40 are preferably designed to have non-linear stiffness so that they become stiffer at higher applied loads. The nonlinear stiffness simulates physiological intervertebral stiffness.
One skilled in the art will recognize other embodiments contemplated by the present invention. For example, the comprsssible member 18 may comprise a plurality of springs extending between, and directly - connected to, support members 32 and 34. Alternatively, the compressible member 18 may comprise a single spring with a relatively large coil diameter (not shown) extending between, and directly connected to, the support members 32 and 34. Any spring arrangement may be utilized that achieves sufficient axial compressive force to replicate the biomechanics of the natural disc.
In each embodiment, the compressible member includes an imaginary longitudinal axis, shown by the dashed line C-C in Figure 2, and an outer periphery in a plane transverse to the longitudinal axis C-C. A largest dimension of the compressible members outer periphery is less than or substantially egual to the diameter of a nucleus pulposus of the natural intervertebral disc.
Put another way, the annulus fibrosis of the natural disc, which is substantially preserved in the WO X50 PCTfUS9?fI~6i8 .
-lI=
implantation procedure, circumscribes the compressible member i8. For example, where the compressible member comprises a plurality of springs, the outer periphery ' of the compressible member circumscribes the springs, and the largest dimension of that outer periphery may extend to, but does not extend beyond, the nucleus pulposus. In other embodiment, where the compressible member includes a top plate and a bottom plate, and where those plates fit within the annulus fibrosis and extend beyond the outermost portions of the springs, the outer periphery equals the larger of the two plate peripheries.
In quantitative terms, the outer periphery of the . compressible member preferably ranges between 2.0 cm to 3.0 cm, which approximates the diameter of the nucleus pulposus of a natural intervertebral disc.
Figures 3A-3C show three embodiments of a coil spring designed to possess non-linear stiffness. In the embodiment of Figure 3A, the coil spring 54 has a variable, or non-uniform, cross-sectional diameter 56.
Figure 3B shows another embodiment in which a coil spring 58 has a variable pitch 60, where the pitch is defined ' as the distance between successive coils of the spring 58. Figure 3C shows a third embodiment of a coil spring 62 in which at least two of the spring coils have different radii 64 measured from an imaginary axis D-D
extending along the central axis of the spring 62.
Figure 4 shows a preferred embodiment of the first fixation member 14. In the embodiment shown in Figure 1, the second fixation member 1~ is structurally similar to the first fixation member 14, but inverted. The following discussion thus also applies to the second fixation member 16.
The fixation member Z4 comprises an adjustable member , genera l ly indicated 2 8 , and a support member 3 2 .
The adjustable member 28 is adjustable in an axial direction by adjustment elements 24. The adjustment elements 24 preferably comprise telescopic struts a WO 901Z?,05(1 PCTlU897Ii9610 _ extending between a first plate 31 and a second plate 33. In a preferred embodiment, the first plate 31 has a bone-contacting surface, such as 27 shown in an operative context in Figure 1, and the second plate has a surface 35 for positioning against the support member 32. Although the illustrative embodiment shows flat ' plates 31 and 33, it will be understood by those skilled in the art that these structures need not be flat and may, for example, have undulating surfaces. In fact, in one embodiment, the bone-contacting surface 27 of the first plate 31 is concave to match the contour of the subchondral bone of the associated vertebral body.
The adjustment elements 24 adjust the distance between the f first bone-contacting plate 31 and the second plate 33, thus adjusting the height of the adjustable member 28. A surgeon may adjust the telescopic struts to increase the height of the adjustable member and thus pre-load the compressible member to mechanically reproduce the axial compression absorbed by a nucleus pulposus of a natural disc. Pre-loading the compressible member restores the intervertebral height at the - operative joint and restores the function of the annulus fibrosis. The annulus fibrosis load shares with the compressible member which reduces implant/tissue interface stresses.
Each telescopic strut is provided with a lock screw 63 to adjust the length of the strut 24 and hence control the height of the adjustable member. The lock screw 63 may comprise, for example, a pin (not shown) that extends through both the telescoping portion 65 and the housing portion 67 of the strut 24. Each strut 24 is independently adjustable. Figure 5 shows a top view of the second plate 33 of the adjustable member 28. The -ad justment elements 24 preferably are spaced equidistant from each other to enable specific height adjustment of various regions of the adjustable member.
wo ~sn~so rc°r.~s~rro A key feature of the present invention is that controlling the height of the adjustable membe~cs 28 and 30, along with :electing an appropriately-sized support member, controls the "disc" height. The diec height is defined as the axial distance between the vertebrae above and below the operative disc. In addition to restoring the disc height, the compressible member 18 acts as a shock absorber to minimize impact loading and, thus, minimize device failure or vertebral fracture.
In a preferred embodiment, the first and second fixation members 14 and 16 have porous portions, such as the bone-contacting surface 27, to permit bone ingrowth. In another embodiment, a biocompatible fabric or suitable material may be wrapped around the f fixation members to enable bone ingrowth. The pre8ent prosthetic device does not require conventional mechanical attachments, such as pegs or screws, to hold the prosthesis permanently in place. The present prosthetic device, however, may include mechanical or other attachments to supplement the porous portions of the fixation members and to temporarily fix the prosthetic device in place until bone ingrowth has occurred.
To further promote bone ingrowth, the adjustment elements 24 may include fins 66 extending outward from an exterior surface of the element 24, as shown in Figure 4 . The f ins 66 increase the surface area of the fixation member 14 to which bone may attach. Preferably, these fins 66 ate located on the adjustment elements that are positioned on the anterior side of the adjustable member 28. The present prosthetic device also may include protuberances (not shown) on the bone-contacting surface of the adjustable members to increase the surface area of the porous portion of the fixation members and, thus, encourage bone ingrowth.
Figure 6 shows a cross-section of support member 32. The support member 32 has a first surface 72 that operably faces away from the compressible member 18 and W0 9A8/~030 PCT/I199'1/196H1 -ly-a second surface 74 that operably faces towards the compressible member 18. The first and second surfaces 72 and 74 are oblique so that a circumferential surface 77 around the support member 32 varies in width, as shown in Figure 4. The support member 32 thus is wedge-shaped.
In other words , the support member 3 2 preferably tapers from a maximum thickness at one side 73 to a minimum thickness at an opposite side 75. Generally, the support member 32 is thicker on the side of the fixation member 14 placed anteriorly in a patient ~ s spine to account for the spines natural curvature.
The support members are constructed with various thicknesses and with various angled surfaces, depending upon the vertebral level of the operative intervertebral joint. An angle a shown in Figure 6 ranges between 3-l0 degrees. The support members are shaped to maintain sagittal alignment. Maintaining sagittal alignment avoids nonuniform loading of the compressible member and avoids early fatigue failure of that member.
Figure 7 shows another embodiment of the present intervertebral prosthetic device, generally indicated 7 6 , which comprises a f first fixation member 78 , a second fixation member 80, and a compressible member 82. The compressible member 82 is positioned between the first and second fixation members 78 and 80. The second fixation member comprises a wedge-shaped support member with an upper surface 84 that attaches to the compressible member 82 and a lower surface 86 that rests upon subchondral bone of a near end-plate 88 of an inferior vertebral body. In this embodiment, adjustment of the first fixation member 78 pre-loads the compressible member 82 to an appropriate extent. This embodiment is particularly suited for young patients.
Also, in this embodiment, a lower surface 86 of the support member 80 has a slightly convex shape to match the natural contour of the near end-plate of the inferior W0 X22030 PCT/US97l1lb~A ..
vertebral body. The surface 86 is preferably composed of a porous material.
As evident from the embodiments of Figures 1 and 7, the present intervertebral prosthetic device has a modular design so that the prosthesis may be sized to the patient's anatomy and designed for the patient's condition. The modular design also enables replacement of individual comgonents of the prosthesis (i.e., an adjustable member, a support member, or a compressible member), rather than replacement of the entire prosthesis should one component fail. The compressible member is preferably attached to the fixation members by mechanical attachments, such screws, rather than bone cement so that a surgeon may easily replace damaged or worn components.
25 Moreover, because the present prosthetic device has no ball bearings, rollers, or hinges, it produces little wear debris. And, because the present prosthetic device need not include plastic polymers or elastomeric components, the present prosthetic device does not degrade under long-term cyclic loading conditions.
The present prosthetic device comprises biocompatible metallic materials, preferably a titanium alloy having, for example, 4% vanadium and 6% aluminum.
. Persons of skill in the art will recognize other suitable materials, for example, a cobalt-chromium alloy, such as alloy number 301. Alternatively, the present prosthetic device, with the exception of the springs of the compressible member, may comprise a ceramic material, such as aluminium oxide and zirconium oxide. The porous surfaces of the bone-contacting member and support member may be coated with hydroxyapatite or bioactive proteins (e. g., bone morphcx~enic protein) to encourage bone ingrowth.
A method of intervert~bral disc replaceaent now will be described in connection with Figures 8-14. Figure 8 shows a pathological intervertebral disc 90 located between a superior vertebral body 92 and an inferior vertebral body 94. Prior to implantation, a surgeon performs a partial vertebrectomy to excise bone matter from the superior vertebral body 92 for receipt of a fixation member. The partial vertebrectomy creates a cavity bounded by subchondral bone of a distant end-plate 96 and subchondral bone of a near end-plate 98 of the superior vertebral body 92. Figure 9 shows a cross sectional view of the superior vertebral body 92 after the partial vertabrectony, as taken along line 9-9 in Figure 8.
The surgeon next excises the nucleus pulposus of the damaged disc to create a cavity 100, as shown in Figure 10, for receipt of the compressible member. The annulus fibrosis 102, seen in Figure 11, is maintained.
The surgeon may perform a partial vertebrectomy on the inferior vertebral body or may excise cartilage matter only to the near end-plate, depending upon whether the surgeon implants the embodiment shown in Figure 1 or the embodiment shown in Figure 7, respectively. The 2o following description details implantation of the prosthesis .shown in Figure 1; however, one of skill in ' the art would understand how to modify the procedure described below to implant the prosthesis of Figure 7.
Upon completion of the partial vertebrectomies, the surgeon implants a fixation member 104 into the inferior vertebral body 94, as shown in Figure 11. The surgeon selects a support member with an appropriate thickness to accommodate the angulation at the operative intervertebral levels. The surgeon then inserts a compressible member 106 into the cavity formerly containing the nucleus pulposus of the damaged disc and connects it to the fixation member 104, as shown in Figure 12 . The compressible member 106 and the f fixation member 104 nay be connected by conventional attachment members, such as screws, or by biocompatible cement or a suitable adhesive composition. Finally, the surgeon i~aplants another fixation member, similar to the one wo 9sn~oso rc~rn~rs9~i:mo _ -17~
implanted in the inferior vertebral body 94, yet inverted, in the superior vertebral body 92. Connection of that fixation member to the compressible member 106 forms an intervertebral prosthetic device like the one shown in Figure 1.
once the fixation menbsrs are in plat~, the surgeon expands each adjustable member, one at a tile, by placing a spreader device with a calibrated tensiometer between the first and second plates of the adjustable member.
The surgeon applies distraction until the adjustable member is seated against the subchondral bone of the vertebral body and until the desired compression has been applied to the compressible member. The adjustment elements of the adjustable member are then secured.
Figure 13 shows rotation of the lock screws 112 of individual telescopic struts 108 to secure the struts at an appropriate height.
The surgeon next packs cancellous bone grafts 118 around the struts of each adjustable member, as shown in Figure 14. The growth of bone around the fixation member and into its porous surfaces secures the intervertebrai prosthetic device in place, absent mechanical attachments typically used in conventional disc prostheses. The surgeon then replaces the cortical bone from the partial vertebrectomy procedure and secures it with a bone screw or bone cement.
Additional advantages and modifications will readily occur to those skilled in the art. Therefore, the invention in ita broader aspects is not limited to the specific details, and representative devices, shown and described herein. Accordingly, various modifications may be made without departing from the spirit or scope of the general inventive concept as defined by the appended claims and their equivalents.
Claims (83)
1. An intervertebral prosthetic device for replacement of a nucleus pulposus of an intervertebral disc, comprising:
a first intravertebral fixation member for fixation within a cavity of a first vertebral body, said first fixation member having a bone-contacting surface for positioning against subchondral bone of the first vertebral body; said first fixation member having at least one adjustable member for adjusting a length of said first fixation member;
a second intravertebral fixation member for fixation within a cavity of a second vertebral body adjacent the first vertebral body, said second fixation member having a bone-contacting surface for positioning against subchondral bone of the second vertebral body;
and a compressible member for positioning between said first fixation member and said second fixation member, said compressible member having a top plate connected to said first fixation member, a bottom plate connected to said second fixation member, and at least one compressible element therebetween that remains compressible after implantation, said compressible member further having an outer periphery less than or substantially equal to a diameter of the nucleus pulposus of the intervertebral disc.
a first intravertebral fixation member for fixation within a cavity of a first vertebral body, said first fixation member having a bone-contacting surface for positioning against subchondral bone of the first vertebral body; said first fixation member having at least one adjustable member for adjusting a length of said first fixation member;
a second intravertebral fixation member for fixation within a cavity of a second vertebral body adjacent the first vertebral body, said second fixation member having a bone-contacting surface for positioning against subchondral bone of the second vertebral body;
and a compressible member for positioning between said first fixation member and said second fixation member, said compressible member having a top plate connected to said first fixation member, a bottom plate connected to said second fixation member, and at least one compressible element therebetween that remains compressible after implantation, said compressible member further having an outer periphery less than or substantially equal to a diameter of the nucleus pulposus of the intervertebral disc.
2. A prosthetic device according to claim 1 wherein said first fixation member comprises a first support member and a first adjustable member that is positioned against said first support member and that adjusts along a longitudinal axis of said first adjustable member.
3. A prosthetic device according to claim 2 wherein said second fixation member comprises a second support member and a second adjustable member that is positioned against said first support member and that adjusts along a longitudinal axis of said second adjustable member.
4. A prosthetic device according to claim 3 wherein said first adjustable member and said second adjustable member each have at least one adjustment element that adjusts a length of a respective one of said first adjustable member and said second adjustable member.
5. A prosthetic device according to claim 4 wherein:
each of said first adjustable member and said second adjustable member has a first plate and a second plate;
said at least one adjustment element of said first adjustable member comprises a telescopic strut extending between said first plate and said second plate of said first adjustable member, and said at least one adjustment element of said second adjustable member comprises a telescopic strut extending between said first plate and said second plate of said second adjustable member.
each of said first adjustable member and said second adjustable member has a first plate and a second plate;
said at least one adjustment element of said first adjustable member comprises a telescopic strut extending between said first plate and said second plate of said first adjustable member, and said at least one adjustment element of said second adjustable member comprises a telescopic strut extending between said first plate and said second plate of said second adjustable member.
6. A prosthetic device according to claim 4 wherein said at least one adjustment element has an exterior surface and a fin extending outward from said exterior surface.
7. A prosthetic device according to claim 1 wherein said compressible member comprises at least one spring.
8. A prosthetic device according to claim 1 wherein each said bone-contacting surface is porous.
9. An intervertebral prosthetic device for replacement of a nucleus pulposus of an intervertebral disc, comprising:
a first intravertebral fixation member for fixation within a cavity of a first vertebral body, said first fixation member having an adjustable member and a support member, said adjustable member having a bone-contacting portion, an other portion for positioning against said support member, and at least one adjustment element extending between said bone-contacting portion and said other portion for adjusting a distance between said bone-contacting portion and said other portion;
a second intravertebral fixation member for fixation within a cavity of a second vertebral body adjacent the first vertebral body; and a compressible member positioned between said first fixation member and said second fixation member, said compressible member remaining compressible after implantation and being dimensioned to operably replace the nucleus pulposus of the intervertebral disc.
a first intravertebral fixation member for fixation within a cavity of a first vertebral body, said first fixation member having an adjustable member and a support member, said adjustable member having a bone-contacting portion, an other portion for positioning against said support member, and at least one adjustment element extending between said bone-contacting portion and said other portion for adjusting a distance between said bone-contacting portion and said other portion;
a second intravertebral fixation member for fixation within a cavity of a second vertebral body adjacent the first vertebral body; and a compressible member positioned between said first fixation member and said second fixation member, said compressible member remaining compressible after implantation and being dimensioned to operably replace the nucleus pulposus of the intervertebral disc.
10. An intervertebral prosthetic device according to claim 9 wherein said second fixation member has an adjustable member and a support member, said adjustable member of said second fixation member having a bone-contacting portion, an other portion for positioning against said support member of said second fixation member, and at least one adjustment element for adjusting a distance between said bone-contacting portion of said second adjustable member and said other portion of said second adjustable member.
11. An intervertebral prosthetic device according to claim 9 wherein said second fixation member comprises a support member.
12. An intervertebral prosthetic device according to claim 9 wherein said device enables at least four degrees of relative motion between the first vertebral body and the second vertebral body.
13. An intervertebral prosthetic device for replacement of a nucleus pulposus of an intervertebral disc, comprising:
a first intravertebral fixation member for fixation within a cavity of a first vertebral body and having a first longitudinal axis and at least one adjustment element that adjusts a length dimension of said first fixation member along said first longitudinal axis;
a second intravertebral fixation member for fixation within a cavity of a second vertebral body adjacent the first vertebral body; and a compressible member positioned between said first fixation member and said second fixation member and that remains compressible after implantation at the site of the replaced nucleus pulposus of the intervertebral disc.
a first intravertebral fixation member for fixation within a cavity of a first vertebral body and having a first longitudinal axis and at least one adjustment element that adjusts a length dimension of said first fixation member along said first longitudinal axis;
a second intravertebral fixation member for fixation within a cavity of a second vertebral body adjacent the first vertebral body; and a compressible member positioned between said first fixation member and said second fixation member and that remains compressible after implantation at the site of the replaced nucleus pulposus of the intervertebral disc.
14. A prosthetic device according to claim 13 wherein said first fixation member comprises an adjustable member and a support member, said adjustable member comprising a first bone-contacting plate, a second plate, and said at least one adjustment element, said at least one adjustment element extending between said first bone-contacting plate and said second plate.
15. A prosthetic device according to claim 13 wherein said second fixation member has a second longitudinal axis and at least one adjustment element that adjusts a height of said second fixation member along said second longitudinal axis.
16. A prosthetic device according to claim 15 wherein each said at least one adjustment element has an exterior surface and at least one fin extending outward from said exterior surface.
17. A prosthetic device according to claim 15 wherein each said at least one adjustment element comprises a telescopic strut, and adjustment of each said telescopic strut pre-loads said compressible member.
18. A prosthetic device according to claim 14 wherein said second fixation member comprises an adjustable member and a support member, said adjustable member having a first bone-contacting plate and a second plate, said at least one adjustment element of said second fixation member extending between said first bone-contacting plate of said second fixation member and said second plate of said second fixation member.
19. A prosthetic device according to claim 18 wherein each said first bone-contacting plate has a concave, bone-contacting surface.
20. A prosthetic device according to claim 13 wherein said first fixation member has a first support member for placement between said at least one adjustment element and said compressible member, and said second fixation member comprises a second support member.
21. A prosthetic device according to claim 20 wherein at least one of said first support member and said second support member has a first surface facing away from said compressible member and a second surface facing toward said compressible member, and said first surface and said second surface are oblique.
22. An prosthetic device according to claim 20 wherein at least one of said first support member and said second support member has a circumference that varies in width.
23. A prosthetic device according to claim 13 wherein said compressible member comprises a top plate, a bottom plate, and at least one compressible element extending between said top plate and said bottom plate.
24. A prosthetic device according to claim 23 wherein:
said top plate has a first surface and a second surface, said first surface of said top plate being connectable to said first fixation member, and said bottom plate has a first surface and a second surface, said first surface of said bottom plate being connectable to said second fixation member.
said top plate has a first surface and a second surface, said first surface of said top plate being connectable to said first fixation member, and said bottom plate has a first surface and a second surface, said first surface of said bottom plate being connectable to said second fixation member.
25. A prosthetic device according to claim 23 wherein said at least one compressible element comprises at least one spring.
26. A prosthetic device according to claim 25 wherein said at least one spring comprises a coil spring having a non-uniform cross-sectional diameter.
27. A prosthetic device according to claim 25 wherein said at least one spring has a non-uniform pitch.
28. A prosthetic device according to claim 25 wherein said at least one spring comprises a plurality of coils each having a cross-section, and at least two of said plurality of coils have different cross-sections.
29. A prosthetic device according to claim 18 wherein:
said at least one adjustment element of said first fixation member comprises a plurality of adjustment elements, said plurality of adjustment elements extending between said first bone-contacting plate of said first fixation member and said second plate of said first fixation member, said at least one adjustment element of said second fixation member comprises a plurality of adjustment elements, said plurality of adjustment elements extending between said first bone-contacting plate of said second fixation member and said second plate of said second fixation member, said plurality of adjustment elements being spaced equidistant from each other.
said at least one adjustment element of said first fixation member comprises a plurality of adjustment elements, said plurality of adjustment elements extending between said first bone-contacting plate of said first fixation member and said second plate of said first fixation member, said at least one adjustment element of said second fixation member comprises a plurality of adjustment elements, said plurality of adjustment elements extending between said first bone-contacting plate of said second fixation member and said second plate of said second fixation member, said plurality of adjustment elements being spaced equidistant from each other.
30. A prosthetic device according to claim 29 wherein each of said plurality of adjustment elements is independently adjustable.
31. A prosthetic device according to claim 13 wherein said compressible member has a longitudinal axis and an outer periphery in a plane transverse to said longitudinal axis, a largest dimension of said outer periphery being less than or substantially equal to a diameter of a nucleus pulposus of an intervertebral disc.
32. A prosthetic device according to claim 23 wherein said compressible member has a longitudinal axis and an outer periphery in a plane transverse to said longitudinal axis, said outer periphery comprising a larger one of said periphery around said top plate and said periphery of said bottom plate.
33. A prosthetic device according to claim 13 wherein said compressible member has a longitudinal axis and an outer periphery in a plane transverse to said longitudinal axis, a largest dimension of said outer periphery being less than or substantially equal to 3.0 cm.
34. A prosthetic device according to claim 33 wherein said compressible member comprises a plurality of springs and said outer periphery circumscribes said plurality of springs.
35. A prosthetic device according to claim 13 wherein said first fixation member and said second fixation member each have a porous portion.
36. A prosthetic device according to claim 13 wherein said prosthetic device comprises a biocompatible metallic material.
37. A prosthetic device according to claim 36 wherein said metallic material comprises at least one of a titanium alloy and a cobalt-chromium alloy.
38. A prosthetic device according to claim 18 wherein each said adjustable member and each said support member comprise a ceramic material.
39. A prosthetic device according to claim 38 wherein said ceramic material is at least one of an aluminum oxide and a zirconium oxide.
40. A prosthetic device according to claim 13 wherein said compressible member has a height of approximately 1.5 cm and a diameter of approximately 2.0 to 3.0 cm.
41. An intervertebral prosthetic device for replacement of a nucleus pulposus of an intervertebral disc, comprising:
a first fixation member having a first portion for positioning against subchondral bone within a cavity of a first vertebral body, a second portion opposite said first portion, and a telescopic element extending between said first portion and said second portion to adjust a length dimension of said first fixation member;
a second fixation member having a bone-contacting portion for positioning against subchondral bone of a second vertebral body that is adjacent the first vertebral body; and a compressible member positioned between said second portion of said first fixation member and said second fixation member, said compressible member having at least one compressible element that compresses and expands in response to adjustment of said first fixation member.
a first fixation member having a first portion for positioning against subchondral bone within a cavity of a first vertebral body, a second portion opposite said first portion, and a telescopic element extending between said first portion and said second portion to adjust a length dimension of said first fixation member;
a second fixation member having a bone-contacting portion for positioning against subchondral bone of a second vertebral body that is adjacent the first vertebral body; and a compressible member positioned between said second portion of said first fixation member and said second fixation member, said compressible member having at least one compressible element that compresses and expands in response to adjustment of said first fixation member.
42. A prosthetic device according to claim 29 wherein:
said plurality of adjustment elements of said first fixation member and said second fixation member are spaced between respective ones of said first bone-contacting plate and said second plate equidistant from each other.
said plurality of adjustment elements of said first fixation member and said second fixation member are spaced between respective ones of said first bone-contacting plate and said second plate equidistant from each other.
43. An intervertebral prosthetic device for implantation in a spine, comprising:
a first fixation member for fixation within a cavity of a first vertebral body and having a first longitudinal axis and at least one adjustment element for adjusting a length dimension of said first fixation member along the first longitudinal axis;
a second fixation member configured to be positioned against bone of a second vertebral body adjacent the first vertebral body; and a compressible member positionable between said first fixation member and said second fixation member, said compressible member remaining compressible after implantation.
a first fixation member for fixation within a cavity of a first vertebral body and having a first longitudinal axis and at least one adjustment element for adjusting a length dimension of said first fixation member along the first longitudinal axis;
a second fixation member configured to be positioned against bone of a second vertebral body adjacent the first vertebral body; and a compressible member positionable between said first fixation member and said second fixation member, said compressible member remaining compressible after implantation.
44. A prosthetic device according to claim 43, wherein said first fixation member has a first portion for positioning against bone within the cavity of the first vertebral body and a second portion opposite said first portion, and wherein said compressible member is positionable between said second portion and said second fixation member.
45. A prosthetic device according to claim 43, wherein said compressible member has at least one compressible element operable to compress and expand in response to adjustment of said first fixation member.
46. A prosthetic device according to claim 43, wherein said compressible member has an outer periphery less than or substantially equal to a diameter of the nucleus pulposus of the intervertebral disc.
47. A prosthetic device according to claim 43, wherein said first fixation member comprises a first support member and a first adjustable member that is adjustable along a longitudinal axis of said first adjustable member.
48. A prosthetic device according to claim 47, wherein said first adjustable member has a first plate and a second plate, and said at least one adjustment element is arranged to extend between said first plate and said second plate.
49. A prosthetic device according to claim 48, wherein said at least one adjustment element of said first adjustable member has an exterior surface and a fin extending outward from said exterior surface.
50. A prosthetic device according to claim 48, wherein said at least one adjustment element comprises a plurality of adjustment elements extending between said first plate and said second plate, and said plurality of adjustment elements are spaced equidistant from each other.
51. A prosthetic device according to claim 50, wherein each of said plurality of adjustment elements is independently adjustable.
52. A prosthetic device according to claim 43, wherein said second fixation member is configured to be positioned proximate a near end-plate of the second vertebral body.
53. A prosthetic device according to claim 52, wherein said second fixation member includes a first surface that faces toward said compressible member and a second surface that faces away from said compressible member.
54. A prosthetic device according to claim 53, wherein said second surface is convex.
55. A prosthetic device according to claim 53, wherein said first surface and said second surface are oblique.
56. A prosthetic device according to claim 43, wherein said second fixation member has a circumference that varies in width.
57. A prosthetic device according to claim 43, wherein said second fixation member comprises a support member.
58. A prosthetic device according to claim 57, wherein said support member is wedge-shaped.
59. A prosthetic device according to claim 57, wherein said support member has an upper surface that is attachable to said compressible member and a lower surface configured to rest upon bone of a near end-plate of the second vertebral body.
60. A prosthetic device according to claim 47, wherein said second fixation member is configured for fixation within a cavity of the second vertebral body.
61. A prosthetic device according to claim 60, wherein said second fixation member comprises a second support member and a second adjustable member that is adjustable along a longitudinal axis of said second adjustable member.
62. A prosthetic device according to claim 61, wherein:
said first adjustable member includes said at least one adjustment element for adjusting a height of said first adjustable member, and said second adjustable member includes at least one adjustment element for adjusting a height of said second adjustable member.
said first adjustable member includes said at least one adjustment element for adjusting a height of said first adjustable member, and said second adjustable member includes at least one adjustment element for adjusting a height of said second adjustable member.
63. A prosthetic device according to claim 62, wherein said second adjustable member has a first plate and a second plate, and said at least one adjustment element of said second adjustable member is arranged to extend between said first plate and said second plate.
64. A prosthetic device according to claim 62, wherein:
each of said first adjustable member and said second adjustable member has a first plate and a second plate, said at least one adjustment element of said first adjustable member comprises a telescopic strut extending between said first plate and said second plate of said first adjustable member, and said at least one adjustment element of said second adjustable member comprises a telescopic strut extending between said first plate and said second plate of said second adjustable member.
each of said first adjustable member and said second adjustable member has a first plate and a second plate, said at least one adjustment element of said first adjustable member comprises a telescopic strut extending between said first plate and said second plate of said first adjustable member, and said at least one adjustment element of said second adjustable member comprises a telescopic strut extending between said first plate and said second plate of said second adjustable member.
65. A prosthetic device according to claim 60, wherein said second fixation member has a second longitudinal axis and at least one adjustment element that adjusts a height of said second fixation member along said second longitudinal axis.
66. A prosthetic device according to claim 65, wherein each said at least one adjustment element of said first and second fixation members comprises a telescopic strut, and wherein adjustment of each said telescopic strut pre-loads said compressible member.
67. A prosthetic device according to claim 43, wherein said compressible member comprises at least one spring.
68. A prosthetic device according to claim 43, wherein said device enables at least four degrees of relative motion between the first vertebral body and the second vertebral body.
69. A prosthetic device according to claim 43, wherein said compressible member comprises a top plate, a bottom plate, and at least one compressible element extending between said top plate and said bottom plate.
70. A prosthetic device according to claim 69, wherein said compressible member has a longitudinal axis and an outer periphery in a plane transverse to said longitudinal axis, said outer periphery comprising a larger one of said periphery around said top plate and said periphery of said bottom plate, and a largest dimension of said outer periphery being less than or substantially equal to a diameter of a nucleus pulposus of an invertebral disc.
71. A prosthetic device according to claim 45, wherein said at least one compressible element comprises at least one spring.
72. A prosthetic device according to claim 71, wherein said at least one spring comprises a coil spring having a non-uniform cross-sectional diameter.
73. A prosthetic device according to claim 71, wherein said at least one spring has a non-uniform pitch.
74. A prosthetic device according to claim 71, wherein said at least one spring comprises a plurality of coils each having a cross-section, and at least two of said plurality of coils have different cross-sections.
75. A prosthetic device according to claim 43, wherein said compressible member has a longitudinal axis and an outer periphery in a plane transverse to said longitudinal axis, a largest dimension of said outer periphery being less than or substantially equal to a diameter of a nucleus pulposus of an intervertebral disc.
76. A prosthetic device according to claim 75, wherein said compressible member comprises a plurality of springs and said outer periphery circumscribes said plurality of springs.
77. A prosthetic device according to claim 43, wherein said compressible member has a longitudinal axis and an outer periphery in a plane transverse to said longitudinal axis, a largest dimension of said outer periphery being less than or substantially equal to 3.0 cm.
78. A prosthetic device according to claim 43, wherein said first fixation member and said second fixation member each has a porous portion.
79. A prosthetic device according to claim 43, wherein said prosthetic device comprises a biocompatible metallic material.
80. A prosthetic device according to claim 79, wherein said metallic material comprises at least one of a titanium alloy and a cobalt-chromium alloy.
81. A prosthetic device according to claim 61, wherein each said adjustable member and each said support member comprise a ceramic material.
82. A prosthetic according to claim 81, wherein said ceramic material is at least one of an aluminum oxide and a zirconium oxide.
83. A prosthetic device according to claim 43, wherein said at least one adjustment element comprises at least one telescopic element for adjusting a length dimension of said first fixation member along said first longitudinal axis.
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US08/753,334 | 1996-11-22 | ||
PCT/US1997/019610 WO1998022050A1 (en) | 1996-11-22 | 1997-11-06 | Intervertebral prosthetic device |
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CA2271800A1 CA2271800A1 (en) | 1998-05-28 |
CA2271800C true CA2271800C (en) | 2005-01-18 |
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EP (2) | EP1342456B1 (en) |
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DE (2) | DE69722244T2 (en) |
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WO (1) | WO1998022050A1 (en) |
Families Citing this family (305)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7879095B2 (en) * | 1994-03-18 | 2011-02-01 | Madhavan Pisharodi | Method of inserting, rotating and releasing a spring-loaded artificial disk |
ATE220564T1 (en) | 1997-08-14 | 2002-08-15 | Sulzer Innotec Ag | COMPOSITION AND DEVICE FOR REPAIRING CARTILAGE TISSUE IN VIVO CONSISTING OF NANOCAPSULES WITH OSTEOINDUCTIVE AND/OR CHONDROINDUCTIVE FACTORS |
US6113637A (en) | 1998-10-22 | 2000-09-05 | Sofamor Danek Holdings, Inc. | Artificial intervertebral joint permitting translational and rotational motion |
US6929662B1 (en) | 1999-02-04 | 2005-08-16 | Synthes (Usa) | End member for a bone fusion implant |
US6342074B1 (en) | 1999-04-30 | 2002-01-29 | Nathan S. Simpson | Anterior lumbar interbody fusion implant and method for fusing adjacent vertebrae |
US7331994B2 (en) * | 1999-05-17 | 2008-02-19 | Vanderbilt University | Intervertebral disc replacement prosthesis |
US6964686B2 (en) | 1999-05-17 | 2005-11-15 | Vanderbilt University | Intervertebral disc replacement prosthesis |
US20060247665A1 (en) | 1999-05-28 | 2006-11-02 | Ferree Bret A | Methods and apparatus for treating disc herniation and preventing the extrusion of interbody bone graft |
US7273497B2 (en) | 1999-05-28 | 2007-09-25 | Anova Corp. | Methods for treating a defect in the annulus fibrosis |
US20070038231A1 (en) | 1999-05-28 | 2007-02-15 | Ferree Bret A | Methods and apparatus for treating disc herniation and preventing the extrusion of interbody bone graft |
US6969404B2 (en) * | 1999-10-08 | 2005-11-29 | Ferree Bret A | Annulus fibrosis augmentation methods and apparatus |
US6245107B1 (en) | 1999-05-28 | 2001-06-12 | Bret A. Ferree | Methods and apparatus for treating disc herniation |
US6520996B1 (en) * | 1999-06-04 | 2003-02-18 | Depuy Acromed, Incorporated | Orthopedic implant |
JP3282076B2 (en) * | 1999-09-02 | 2002-05-13 | 桂一 花田 | Human lumbar spine model structure and its utilization device |
US6783546B2 (en) | 1999-09-13 | 2004-08-31 | Keraplast Technologies, Ltd. | Implantable prosthetic or tissue expanding device |
US20030040796A1 (en) * | 1999-10-08 | 2003-02-27 | Ferree Bret A. | Devices used to treat disc herniation and attachment mechanisms therefore |
US7060100B2 (en) * | 1999-10-08 | 2006-06-13 | Ferree Bret A | Artificial disc and joint replacements with modular cushioning components |
US8679180B2 (en) * | 1999-10-08 | 2014-03-25 | Anova Corporation | Devices used to treat disc herniation and attachment mechanisms therefore |
US7615076B2 (en) | 1999-10-20 | 2009-11-10 | Anulex Technologies, Inc. | Method and apparatus for the treatment of the intervertebral disc annulus |
US7935147B2 (en) | 1999-10-20 | 2011-05-03 | Anulex Technologies, Inc. | Method and apparatus for enhanced delivery of treatment device to the intervertebral disc annulus |
US7052516B2 (en) | 1999-10-20 | 2006-05-30 | Anulex Technologies, Inc. | Spinal disc annulus reconstruction method and deformable spinal disc annulus stent |
US6592625B2 (en) | 1999-10-20 | 2003-07-15 | Anulex Technologies, Inc. | Spinal disc annulus reconstruction method and spinal disc annulus stent |
US20030153976A1 (en) | 1999-10-20 | 2003-08-14 | Cauthen Joseph C. | Spinal disc annulus reconstruction method and spinal disc annulus stent |
US8128698B2 (en) | 1999-10-20 | 2012-03-06 | Anulex Technologies, Inc. | Method and apparatus for the treatment of the intervertebral disc annulus |
US7004970B2 (en) | 1999-10-20 | 2006-02-28 | Anulex Technologies, Inc. | Methods and devices for spinal disc annulus reconstruction and repair |
US8632590B2 (en) | 1999-10-20 | 2014-01-21 | Anulex Technologies, Inc. | Apparatus and methods for the treatment of the intervertebral disc |
US7951201B2 (en) | 1999-10-20 | 2011-05-31 | Anulex Technologies, Inc. | Method and apparatus for the treatment of the intervertebral disc annulus |
US7641657B2 (en) | 2003-06-10 | 2010-01-05 | Trans1, Inc. | Method and apparatus for providing posterior or anterior trans-sacral access to spinal vertebrae |
US6500205B1 (en) * | 2000-04-19 | 2002-12-31 | Gary K. Michelson | Expandable threaded arcuate interbody spinal fusion implant with cylindrical configuration during insertion |
US6814756B1 (en) | 2000-02-04 | 2004-11-09 | Gary K. Michelson | Expandable threaded arcuate interbody spinal fusion implant with lordotic configuration during insertion |
EP1645248B8 (en) | 2000-02-04 | 2010-06-16 | Warsaw Orthopedic, Inc. | Expandable interbody spinal fusion implant having pivotally attached blocker |
US6575979B1 (en) | 2000-02-16 | 2003-06-10 | Axiamed, Inc. | Method and apparatus for providing posterior or anterior trans-sacral access to spinal vertebrae |
US6558390B2 (en) | 2000-02-16 | 2003-05-06 | Axiamed, Inc. | Methods and apparatus for performing therapeutic procedures in the spine |
US7547324B2 (en) * | 2000-02-16 | 2009-06-16 | Trans1, Inc. | Spinal mobility preservation apparatus having an expandable membrane |
US7727263B2 (en) | 2000-02-16 | 2010-06-01 | Trans1, Inc. | Articulating spinal implant |
ES2308014T5 (en) | 2000-02-16 | 2012-03-16 | Trans1, Inc. | Apparatus for distraction and spinal fusion |
US6899716B2 (en) | 2000-02-16 | 2005-05-31 | Trans1, Inc. | Method and apparatus for spinal augmentation |
US6558386B1 (en) | 2000-02-16 | 2003-05-06 | Trans1 Inc. | Axial spinal implant and method and apparatus for implanting an axial spinal implant within the vertebrae of the spine |
US6790210B1 (en) | 2000-02-16 | 2004-09-14 | Trans1, Inc. | Methods and apparatus for forming curved axial bores through spinal vertebrae |
US6740093B2 (en) | 2000-02-28 | 2004-05-25 | Stephen Hochschuler | Method and apparatus for treating a vertebral body |
AR027685A1 (en) * | 2000-03-22 | 2003-04-09 | Synthes Ag | METHOD AND METHOD FOR CARRYING OUT |
US6805695B2 (en) | 2000-04-04 | 2004-10-19 | Spinalabs, Llc | Devices and methods for annular repair of intervertebral discs |
US6723335B1 (en) | 2000-04-07 | 2004-04-20 | Jeffrey William Moehlenbruck | Methods and compositions for treating intervertebral disc degeneration |
US6395033B1 (en) * | 2000-04-10 | 2002-05-28 | Tyco Healthcare Group Lp | Dynamic fusion mechanostat devices |
WO2002002022A1 (en) | 2000-06-30 | 2002-01-10 | Stephen Ritland | Polyaxial connection device and method |
US6808537B2 (en) * | 2000-07-07 | 2004-10-26 | Gary Karlin Michelson | Expandable implant with interlocking walls |
US7114501B2 (en) * | 2000-08-14 | 2006-10-03 | Spine Wave, Inc. | Transverse cavity device and method |
US20050154463A1 (en) * | 2000-08-30 | 2005-07-14 | Trieu Hal H. | Spinal nucleus replacement implants and methods |
US7503936B2 (en) | 2000-08-30 | 2009-03-17 | Warsaw Orthopedic, Inc. | Methods for forming and retaining intervertebral disc implants |
CA2549361A1 (en) | 2000-08-30 | 2002-03-07 | Sdgi Holdings, Inc. | Intervertebral disc nucleus implants and methods |
US20020026244A1 (en) | 2000-08-30 | 2002-02-28 | Trieu Hai H. | Intervertebral disc nucleus implants and methods |
US7204851B2 (en) | 2000-08-30 | 2007-04-17 | Sdgi Holdings, Inc. | Method and apparatus for delivering an intervertebral disc implant |
US7166073B2 (en) | 2000-09-29 | 2007-01-23 | Stephen Ritland | Method and device for microsurgical intermuscular spinal surgery |
US6692434B2 (en) | 2000-09-29 | 2004-02-17 | Stephen Ritland | Method and device for retractor for microsurgical intermuscular lumbar arthrodesis |
US6733531B1 (en) * | 2000-10-20 | 2004-05-11 | Sdgi Holdings, Inc. | Anchoring devices and implants for intervertebral disc augmentation |
AU1538702A (en) * | 2000-10-24 | 2002-05-06 | Cryolife Inc | In situ bioprosthetic filler and methods, particularly for the in situ formationof vertebral disc bioprosthetics |
CA2425935C (en) | 2000-11-07 | 2011-03-29 | Cryolife, Inc. | Expandable foam-like biomaterials and methods |
EP1272130B1 (en) | 2001-02-04 | 2004-11-17 | MICHELSON, Gary Karlin | Instrumentation for inserting and deploying an expandable interbody spinal fusion implant |
US7169182B2 (en) | 2001-07-16 | 2007-01-30 | Spinecore, Inc. | Implanting an artificial intervertebral disc |
US6669730B2 (en) | 2001-02-15 | 2003-12-30 | Spinecore, Inc. | Intervertebral spacer device utilizing a spirally slotted belleville washer having radially extending grooves |
US6887274B2 (en) | 2001-02-15 | 2005-05-03 | Spinecore, Inc. | Intervertebral spacer device utilizing a belleville washer having radially spaced concentric grooves |
US7235081B2 (en) | 2001-07-16 | 2007-06-26 | Spinecore, Inc. | Wedge plate inserter/impactor and related methods for use in implanting an artificial intervertebral disc |
US6863688B2 (en) | 2001-02-15 | 2005-03-08 | Spinecore, Inc. | Intervertebral spacer device utilizing a spirally slotted belleville washer having radially spaced concentric grooves |
US7563285B2 (en) | 2001-07-16 | 2009-07-21 | Spinecore, Inc. | Artificial intervertebral disc utilizing a ball joint coupling |
US6764515B2 (en) | 2001-02-15 | 2004-07-20 | Spinecore, Inc. | Intervertebral spacer device utilizing a spirally slotted belleville washer and a rotational mounting |
US6989032B2 (en) | 2001-07-16 | 2006-01-24 | Spinecore, Inc. | Artificial intervertebral disc |
US20050125064A1 (en) * | 2001-02-15 | 2005-06-09 | Spinecore, Inc. | Intervertebral spacer device |
US7604664B2 (en) | 2001-07-16 | 2009-10-20 | Spinecore, Inc. | Spinal baseplates with ball joint coupling and a retaining member |
US8940047B2 (en) | 2001-02-15 | 2015-01-27 | Spinecore, Inc. | Intervertebral spacer device having recessed notch pairs for manipulation using a surgical tool |
US6740117B2 (en) * | 2001-02-15 | 2004-05-25 | Spinecore, Inc. | Intervertebral spacer device having a radially thinning slotted belleville spring |
US6673113B2 (en) | 2001-10-18 | 2004-01-06 | Spinecore, Inc. | Intervertebral spacer device having arch shaped spring elements |
US20030078579A1 (en) * | 2001-04-19 | 2003-04-24 | Ferree Bret A. | Annular repair devices and methods |
FR2824261B1 (en) | 2001-05-04 | 2004-05-28 | Ldr Medical | INTERVERTEBRAL DISC PROSTHESIS AND IMPLEMENTATION METHOD AND TOOLS |
DE10132588C2 (en) * | 2001-07-05 | 2003-05-22 | Fehling Instr Gmbh | Disc prosthesis |
US6527806B2 (en) | 2001-07-16 | 2003-03-04 | Third Millennium Engineering, Llc | Intervertebral spacer device having a spiral wave washer force restoring element |
US7160327B2 (en) * | 2001-07-16 | 2007-01-09 | Spinecore, Inc. | Axially compressible artificial intervertebral disc having limited rotation using a captured ball and socket joint with a solid ball and compression locking post |
DE60231718D1 (en) * | 2001-07-16 | 2009-05-07 | Spinecore Inc | ARTIFICIAL BELT WASH WITH A FORCE RESTORING ELEMENT IN THE FORM OF A WAVE WASHER |
US7118599B2 (en) | 2001-07-16 | 2006-10-10 | Spinecore, Inc. | Artificial intervertebral disc |
US6468310B1 (en) * | 2001-07-16 | 2002-10-22 | Third Millennium Engineering, Llc | Intervertebral spacer device having a wave washer force restoring element |
JP4249021B2 (en) | 2001-09-28 | 2009-04-02 | リットランド、ステファン | Connecting rod for screw or hook multi-axis system and method of use |
US6991632B2 (en) | 2001-09-28 | 2006-01-31 | Stephen Ritland | Adjustable rod and connector device and method of use |
US7713302B2 (en) | 2001-10-01 | 2010-05-11 | Spinecore, Inc. | Intervertebral spacer device utilizing a spirally slotted belleville washer having radially spaced concentric grooves |
US7208014B2 (en) * | 2001-10-01 | 2007-04-24 | Spinecore, Inc. | Intervertebral spacer device utilizing a belleville washer having radially extending grooves |
US7771477B2 (en) * | 2001-10-01 | 2010-08-10 | Spinecore, Inc. | Intervertebral spacer device utilizing a belleville washer having radially spaced concentric grooves |
US20090177283A9 (en) * | 2001-10-01 | 2009-07-09 | Ralph James D | Intervertebral spacer device utilizing a spirally slotted belleville washer and a rotational mounting |
US7179295B2 (en) * | 2001-10-05 | 2007-02-20 | Nebojsa Kovacevic | Prosthetic shock absorber |
WO2003032801A2 (en) * | 2001-10-18 | 2003-04-24 | Third Millennium Engineering Llc | Artificial intervertebral disc having a spider spring force restoring element |
US6572653B1 (en) * | 2001-12-07 | 2003-06-03 | Rush E. Simonson | Vertebral implant adapted for posterior insertion |
US7232802B2 (en) | 2001-12-21 | 2007-06-19 | Zimmer Orthobiologics, Inc. | Compositions and methods for promoting myocardial and peripheral angiogenesis |
US6736850B2 (en) * | 2001-12-28 | 2004-05-18 | Spinal Concepts, Inc. | Vertebral pseudo arthrosis device and method |
US6761723B2 (en) * | 2002-01-14 | 2004-07-13 | Dynamic Spine, Inc. | Apparatus and method for performing spinal surgery |
US7708776B1 (en) | 2002-01-16 | 2010-05-04 | Nuvasive, Inc. | Intervertebral disk replacement system and methods |
ATE476930T1 (en) | 2002-02-20 | 2010-08-15 | Stephen Ritland | DEVICE FOR CONNECTING HAND SCREWS |
AU2003212914A1 (en) * | 2002-02-25 | 2003-09-09 | Dinh, Dzung H | Methods and apparatuses for promoting fusion of vertebrae |
US6783547B2 (en) | 2002-04-05 | 2004-08-31 | Howmedica Corp. | Apparatus for fusing adjacent bone structures |
US6966910B2 (en) | 2002-04-05 | 2005-11-22 | Stephen Ritland | Dynamic fixation device and method of use |
US20080027548A9 (en) | 2002-04-12 | 2008-01-31 | Ferree Bret A | Spacerless artificial disc replacements |
US8038713B2 (en) | 2002-04-23 | 2011-10-18 | Spinecore, Inc. | Two-component artificial disc replacements |
WO2003094699A2 (en) | 2002-05-08 | 2003-11-20 | Stephen Ritland | Dynamic fixation device and method of use |
US7041309B2 (en) | 2002-06-13 | 2006-05-09 | Neuropro Technologies, Inc. | Spinal fusion using an HMG-CoA reductase inhibitor |
US7622562B2 (en) | 2002-06-26 | 2009-11-24 | Zimmer Orthobiologics, Inc. | Rapid isolation of osteoinductive protein mixtures from mammalian bone tissue |
US6793678B2 (en) * | 2002-06-27 | 2004-09-21 | Depuy Acromed, Inc. | Prosthetic intervertebral motion disc having dampening |
WO2004016205A2 (en) | 2002-08-15 | 2004-02-26 | Coppes Justin K | Intervertebral disc implant |
EP1542626B1 (en) | 2002-08-15 | 2012-09-26 | Synthes GmbH | Controlled artificial intervertebral disc implant |
US7101400B2 (en) * | 2002-08-19 | 2006-09-05 | Jeffery Thramann | Shaped memory artificial disc and methods of engrafting the same |
US20060293753A1 (en) * | 2002-08-19 | 2006-12-28 | Lanx, Llc | Corrective artificial disc |
DE10242331B4 (en) * | 2002-09-12 | 2005-10-20 | Biedermann Motech Gmbh | Placeholder for vertebral bodies or intervertebral discs |
DE10242329B4 (en) * | 2002-09-12 | 2005-03-17 | Biedermann Motech Gmbh | Disc prosthesis |
US8679179B2 (en) * | 2002-10-03 | 2014-03-25 | Anova Corp. | Annular repair devices and methods |
US20040106998A1 (en) * | 2002-10-04 | 2004-06-03 | Ferree Bret A. | Multiaxial artificial disc replacements |
US7273496B2 (en) * | 2002-10-29 | 2007-09-25 | St. Francis Medical Technologies, Inc. | Artificial vertebral disk replacement implant with crossbar spacer and method |
US7083649B2 (en) * | 2002-10-29 | 2006-08-01 | St. Francis Medical Technologies, Inc. | Artificial vertebral disk replacement implant with translating pivot point |
AR037168A1 (en) * | 2002-10-30 | 2004-10-27 | Carrasco Mauricio Rodolfo | IMPLANT FOR VERTEBRAL REPLACEMENT AND RESTORATION OF THE NORMAL SPINAL CURVATURE. |
US20040133278A1 (en) * | 2002-10-31 | 2004-07-08 | Marino James F. | Spinal disc implant |
FR2846550B1 (en) | 2002-11-05 | 2006-01-13 | Ldr Medical | INTERVERTEBRAL DISC PROSTHESIS |
US7320708B1 (en) * | 2002-11-13 | 2008-01-22 | Sdgi Holdings, Inc. | Cervical interbody device |
US6974479B2 (en) * | 2002-12-10 | 2005-12-13 | Sdgi Holdings, Inc. | System and method for blocking and/or retaining a prosthetic spinal implant |
US20040210310A1 (en) * | 2002-12-10 | 2004-10-21 | Trieu Hai H. | Implant system and method for intervertebral disc augmentation |
US7101398B2 (en) * | 2002-12-31 | 2006-09-05 | Depuy Acromed, Inc. | Prosthetic facet joint ligament |
US20050055096A1 (en) * | 2002-12-31 | 2005-03-10 | Depuy Spine, Inc. | Functional spinal unit prosthetic |
US7235101B2 (en) * | 2003-09-15 | 2007-06-26 | Warsaw Orthopedic, Inc. | Revisable prosthetic device |
US6908484B2 (en) | 2003-03-06 | 2005-06-21 | Spinecore, Inc. | Cervical disc replacement |
AU2003209911A1 (en) * | 2003-03-24 | 2004-10-18 | Synthes Gmbh | Vertebral disc or intervertebral disc prosthesis |
WO2004089240A2 (en) | 2003-04-04 | 2004-10-21 | Theken Disc, Llc | Artificial disc prosthesis |
US7419505B2 (en) * | 2003-04-22 | 2008-09-02 | Fleischmann Lewis W | Collapsible, rotatable, and tiltable hydraulic spinal disc prosthesis system with selectable modular components |
US7105024B2 (en) | 2003-05-06 | 2006-09-12 | Aesculap Ii, Inc. | Artificial intervertebral disc |
US7291173B2 (en) | 2003-05-06 | 2007-11-06 | Aesculap Ii, Inc. | Artificial intervertebral disc |
DE20308171U1 (en) * | 2003-05-21 | 2003-07-31 | Aesculap Ag & Co Kg | Vertebral body replacement implant |
US8262571B2 (en) | 2003-05-22 | 2012-09-11 | Stephen Ritland | Intermuscular guide for retractor insertion and method of use |
AU2003288494A1 (en) * | 2003-06-02 | 2005-01-21 | Impliant Ltd. | Spinal disc prosthesis |
US7537612B2 (en) * | 2003-06-20 | 2009-05-26 | Warsaw Orthopedic, Inc. | Lumbar composite nucleus |
DE20310433U1 (en) | 2003-07-08 | 2003-09-04 | Aesculap Ag & Co Kg | Surgical device for inserting dual component implant into appropriate space at spine, comprising particularly shaped holding area |
DE10330698B4 (en) | 2003-07-08 | 2005-05-25 | Aesculap Ag & Co. Kg | Intervertebral implant |
US7153325B2 (en) * | 2003-08-01 | 2006-12-26 | Ultra-Kinetics, Inc. | Prosthetic intervertebral disc and methods for using the same |
US7753958B2 (en) | 2003-08-05 | 2010-07-13 | Gordon Charles R | Expandable intervertebral implant |
US7909869B2 (en) | 2003-08-05 | 2011-03-22 | Flexuspine, Inc. | Artificial spinal unit assemblies |
US7799082B2 (en) * | 2003-08-05 | 2010-09-21 | Flexuspine, Inc. | Artificial functional spinal unit system and method for use |
EP1651150B1 (en) * | 2003-08-07 | 2021-03-24 | Dynamic Spine, Inc. | Intervertebral prosthetic device and associated devices and methods for implanting the intervertebral prosthetic device |
DE20313183U1 (en) | 2003-08-22 | 2003-10-16 | Aesculap Ag & Co Kg | Intervertebral implant |
US7513900B2 (en) * | 2003-09-29 | 2009-04-07 | Boston Scientific Scimed, Inc. | Apparatus and methods for reducing compression bone fractures using high strength ribbed members |
ES2325989T3 (en) * | 2003-09-29 | 2009-09-28 | Synthes Gmbh | DEVICE FOR THE ELASTIC STABILIZATION OF THE VERTEBRAL BODIES. |
US7655012B2 (en) | 2003-10-02 | 2010-02-02 | Zimmer Spine, Inc. | Methods and apparatuses for minimally invasive replacement of intervertebral discs |
DE20315613U1 (en) * | 2003-10-08 | 2003-12-11 | Aesculap Ag & Co. Kg | Intervertebral implant |
US7819922B2 (en) * | 2003-10-16 | 2010-10-26 | Spinal Generations, Llc | Vertebral prosthesis |
AU2004283727A1 (en) | 2003-10-23 | 2005-05-06 | Trans1 Inc. | Tools and tool kits for performing minimally invasive procedures on the spine |
US7670377B2 (en) | 2003-11-21 | 2010-03-02 | Kyphon Sarl | Laterally insertable artifical vertebral disk replacement implant with curved spacer |
US7217291B2 (en) | 2003-12-08 | 2007-05-15 | St. Francis Medical Technologies, Inc. | System and method for replacing degenerated spinal disks |
US20050165487A1 (en) | 2004-01-28 | 2005-07-28 | Muhanna Nabil L. | Artificial intervertebral disc |
FR2865629B1 (en) | 2004-02-04 | 2007-01-26 | Ldr Medical | INTERVERTEBRAL DISC PROSTHESIS |
ES2363154T3 (en) | 2004-02-04 | 2011-07-22 | Ldr Medical | INTERVERTEBRAL DISK PROSTHESIS. |
US7393361B2 (en) | 2004-02-20 | 2008-07-01 | Spinecore, Inc. | Artificial intervertebral disc having a bored semispherical bearing with a compression locking post and retaining caps |
WO2005081884A2 (en) | 2004-02-20 | 2005-09-09 | Spinecore, Inc. | Artificial intervertebral disc having a universal joint |
US7806933B2 (en) * | 2004-03-15 | 2010-10-05 | Warsaw Orthopedic, Inc. | System and method for stabilizing a prosthetic device |
US20070032873A1 (en) * | 2005-08-02 | 2007-02-08 | Perumala Corporation | Total artificial intervertebral disc |
US8480742B2 (en) * | 2005-08-02 | 2013-07-09 | Perumala Corporation | Total artificial disc |
US7637927B2 (en) * | 2004-03-25 | 2009-12-29 | Hyde Jr Edward R | Transosseous spine core approach method implant and instrumentation |
US8070816B2 (en) * | 2004-03-29 | 2011-12-06 | 3Hbfm, Llc | Arthroplasty spinal prosthesis and insertion device |
FR2869528B1 (en) | 2004-04-28 | 2007-02-02 | Ldr Medical | INTERVERTEBRAL DISC PROSTHESIS |
WO2005112833A1 (en) * | 2004-05-20 | 2005-12-01 | Pearsalls Limited | Improvements in and relating to surgical implants |
DE102004028967B4 (en) | 2004-06-16 | 2006-05-24 | Aesculap Ag & Co. Kg | Intervertebral implant |
US7604638B2 (en) * | 2004-06-21 | 2009-10-20 | Depuy Spine, Inc. | Instruments and methods for holding a bone plate |
CA2570192C (en) | 2004-06-30 | 2011-08-16 | Synergy Disc Replacement, Inc. | Artificial spinal disc |
US8172904B2 (en) | 2004-06-30 | 2012-05-08 | Synergy Disc Replacement, Inc. | Artificial spinal disc |
US9237958B2 (en) | 2004-06-30 | 2016-01-19 | Synergy Disc Replacement Inc. | Joint prostheses |
FR2874350B1 (en) * | 2004-08-18 | 2007-12-21 | Faurecia Interieur Ind Snc | MOLD FOR INJECTION MOLDING OF A PLASTIC PIECE AND MOLDING METHOD |
US7303074B2 (en) * | 2004-09-22 | 2007-12-04 | Dombrowski Trudy M | Foldable organizer device |
EP1639968A1 (en) * | 2004-09-23 | 2006-03-29 | Cervitech, Inc. | Implant with a part to be inserted and anchored in a bone cavity |
US20060089719A1 (en) * | 2004-10-21 | 2006-04-27 | Trieu Hai H | In situ formation of intervertebral disc implants |
US8597360B2 (en) | 2004-11-03 | 2013-12-03 | Neuropro Technologies, Inc. | Bone fusion device |
FR2879436B1 (en) | 2004-12-22 | 2007-03-09 | Ldr Medical | INTERVERTEBRAL DISC PROSTHESIS |
US7309357B2 (en) | 2004-12-30 | 2007-12-18 | Infinesse, Corporation | Prosthetic spinal discs |
US7585324B2 (en) * | 2005-03-03 | 2009-09-08 | Cervical Xpand, Llc | Cervical intervertebral stabilizer |
US7799080B2 (en) * | 2005-04-22 | 2010-09-21 | Doty Keith L | Spinal disc prosthesis and methods of use |
US7361192B2 (en) | 2005-04-22 | 2008-04-22 | Doty Keith L | Spinal disc prosthesis and methods of use |
US20060293752A1 (en) * | 2005-06-27 | 2006-12-28 | Missoum Moumene | Intervertebral disc prosthesis and associated methods |
FR2887762B1 (en) | 2005-06-29 | 2007-10-12 | Ldr Medical Soc Par Actions Si | INTERVERTEBRAL DISC PROSTHESIS INSERTION INSTRUMENTATION BETWEEN VERTEBRATES |
US20070010848A1 (en) * | 2005-07-11 | 2007-01-11 | Andrea Leung | Systems and methods for providing cavities in interior body regions |
US20070016190A1 (en) * | 2005-07-14 | 2007-01-18 | Medical Device Concepts Llc | Dynamic spinal stabilization system |
US20070016301A1 (en) * | 2005-07-14 | 2007-01-18 | Medical Device Concepts Llc. | Multi-axial interbody spacer device |
EP1906885B2 (en) | 2005-07-19 | 2019-01-16 | Warsaw Orthopedic, Inc. | Rod extension for extending fusion construct |
EP1912578B1 (en) | 2005-07-28 | 2018-02-07 | NuVasive, Inc. | Total disc replacement system |
US20070050032A1 (en) * | 2005-09-01 | 2007-03-01 | Spinal Kinetics, Inc. | Prosthetic intervertebral discs |
US7731753B2 (en) * | 2005-09-01 | 2010-06-08 | Spinal Kinetics, Inc. | Prosthetic intervertebral discs |
FR2891135B1 (en) | 2005-09-23 | 2008-09-12 | Ldr Medical Sarl | INTERVERTEBRAL DISC PROSTHESIS |
US20070083200A1 (en) * | 2005-09-23 | 2007-04-12 | Gittings Darin C | Spinal stabilization systems and methods |
US8070813B2 (en) * | 2005-09-26 | 2011-12-06 | Coalign Innovations, Inc. | Selectively expanding spine cage, hydraulically controllable in three dimensions for vertebral body replacement |
US9028550B2 (en) | 2005-09-26 | 2015-05-12 | Coalign Innovations, Inc. | Selectively expanding spine cage with enhanced bone graft infusion |
US20080243194A1 (en) * | 2005-09-26 | 2008-10-02 | The Regents Of The University Of California | Articulating instrumentation for dynamic spinal stabilization |
US7985256B2 (en) * | 2005-09-26 | 2011-07-26 | Coalign Innovations, Inc. | Selectively expanding spine cage, hydraulically controllable in three dimensions for enhanced spinal fusion |
US20070088439A1 (en) * | 2005-10-13 | 2007-04-19 | Jeffery Thramann | Artificial disc with endplates having cages to promote bone fusion |
US8357181B2 (en) | 2005-10-27 | 2013-01-22 | Warsaw Orthopedic, Inc. | Intervertebral prosthetic device for spinal stabilization and method of implanting same |
FR2893838B1 (en) | 2005-11-30 | 2008-08-08 | Ldr Medical Soc Par Actions Si | PROSTHESIS OF INTERVERTEBRAL DISC AND INSTRUMENTATION OF INSERTION OF THE PROSTHESIS BETWEEN VERTEBRATES |
WO2007075878A2 (en) * | 2005-12-22 | 2007-07-05 | Endius, Inc. | Methods and devices for replacement of intervertebral discs |
US8083795B2 (en) | 2006-01-18 | 2011-12-27 | Warsaw Orthopedic, Inc. | Intervertebral prosthetic device for spinal stabilization and method of manufacturing same |
US8118869B2 (en) | 2006-03-08 | 2012-02-21 | Flexuspine, Inc. | Dynamic interbody device |
US20070270952A1 (en) * | 2006-04-19 | 2007-11-22 | Spinal Kinetics, Inc. | Prosthetic intervertebral discs implantable by minimally invasive surgical techniques |
US7854765B2 (en) * | 2006-04-20 | 2010-12-21 | Moskowitz Mosheh T | Electronically controlled artificial intervertebral disc with motor assisted actuation systems |
WO2010062971A1 (en) | 2008-11-26 | 2010-06-03 | Anova Corporation | Methods and apparatus for anulus repair |
US9232938B2 (en) | 2006-06-13 | 2016-01-12 | Anova Corp. | Method and apparatus for closing fissures in the annulus fibrosus |
US8834496B2 (en) | 2006-06-13 | 2014-09-16 | Bret A. Ferree | Soft tissue repair methods and apparatus |
US8764835B2 (en) | 2006-06-13 | 2014-07-01 | Bret A. Ferree | Intervertebral disc treatment methods and apparatus |
US7666211B2 (en) | 2006-12-28 | 2010-02-23 | Mi4Spine, Llc | Vertebral disc annular fibrosis tensioning and lengthening device |
US20080009876A1 (en) | 2006-07-07 | 2008-01-10 | Meera Sankaran | Medical device with expansion mechanism |
US7959564B2 (en) | 2006-07-08 | 2011-06-14 | Stephen Ritland | Pedicle seeker and retractor, and methods of use |
US20080033322A1 (en) * | 2006-07-31 | 2008-02-07 | Femsuite, Llc | Systems and methods for measuring cervical dilation |
US9526525B2 (en) | 2006-08-22 | 2016-12-27 | Neuropro Technologies, Inc. | Percutaneous system for dynamic spinal stabilization |
US8173551B2 (en) * | 2006-09-07 | 2012-05-08 | Taiwan Semiconductor Manufacturing Co., Ltd. | Defect reduction using aspect ratio trapping |
US9278007B2 (en) * | 2006-09-26 | 2016-03-08 | Spinal Kinetics, Inc. | Prosthetic intervertebral discs having cast end plates and methods for making and using them |
US8403987B2 (en) * | 2006-09-27 | 2013-03-26 | Spinal Kinetics Inc. | Prosthetic intervertebral discs having compressible core elements bounded by fiber-containing membranes |
US9381098B2 (en) * | 2006-09-28 | 2016-07-05 | Spinal Kinetics, Inc. | Tool systems for implanting prosthetic intervertebral discs |
US8066750B2 (en) | 2006-10-06 | 2011-11-29 | Warsaw Orthopedic, Inc | Port structures for non-rigid bone plates |
US8092534B2 (en) * | 2006-11-16 | 2012-01-10 | Warsaw Orthopedic, Inc. | Revision device |
US8715352B2 (en) | 2006-12-14 | 2014-05-06 | Depuy Spine, Inc. | Buckling disc replacement |
US7905922B2 (en) | 2006-12-20 | 2011-03-15 | Zimmer Spine, Inc. | Surgical implant suitable for replacement of an intervertebral disc |
US20080177389A1 (en) * | 2006-12-21 | 2008-07-24 | Rob Gene Parrish | Intervertebral disc spacer |
US9066811B2 (en) * | 2007-01-19 | 2015-06-30 | Flexuspine, Inc. | Artificial functional spinal unit system and method for use |
US8465546B2 (en) | 2007-02-16 | 2013-06-18 | Ldr Medical | Intervertebral disc prosthesis insertion assemblies |
WO2008106912A1 (en) * | 2007-03-07 | 2008-09-12 | Ulrich Gmbh & Co. Kg | Intervertebral implant having an elastic component |
US20100076559A1 (en) * | 2007-05-04 | 2010-03-25 | Titan Spine, Llc | Composite telescoping anterior interbody spinal implant |
FR2916956B1 (en) | 2007-06-08 | 2012-12-14 | Ldr Medical | INTERSOMATIC CAGE, INTERVERTEBRAL PROSTHESIS, ANCHORING DEVICE AND IMPLANTATION INSTRUMENTATION |
US8298287B2 (en) * | 2007-06-26 | 2012-10-30 | Depuy Spine, Inc. | Intervertebral motion disc with helical shock absorber |
EP2018832B1 (en) * | 2007-07-26 | 2011-09-21 | BIEDERMANN MOTECH GmbH | Intervertebral disc prosthesis |
US8282681B2 (en) | 2007-08-13 | 2012-10-09 | Nuvasive, Inc. | Bioresorbable spinal implant and related methods |
US8267965B2 (en) * | 2007-10-22 | 2012-09-18 | Flexuspine, Inc. | Spinal stabilization systems with dynamic interbody devices |
US8523912B2 (en) * | 2007-10-22 | 2013-09-03 | Flexuspine, Inc. | Posterior stabilization systems with shared, dual dampener systems |
US8157844B2 (en) | 2007-10-22 | 2012-04-17 | Flexuspine, Inc. | Dampener system for a posterior stabilization system with a variable length elongated member |
US8162994B2 (en) * | 2007-10-22 | 2012-04-24 | Flexuspine, Inc. | Posterior stabilization system with isolated, dual dampener systems |
US8182514B2 (en) * | 2007-10-22 | 2012-05-22 | Flexuspine, Inc. | Dampener system for a posterior stabilization system with a fixed length elongated member |
US8187330B2 (en) | 2007-10-22 | 2012-05-29 | Flexuspine, Inc. | Dampener system for a posterior stabilization system with a variable length elongated member |
AU2008316600B2 (en) | 2007-10-25 | 2014-09-18 | Jeffery D. Arnett | Systems and methods for vertebral disc replacement |
US20090157185A1 (en) * | 2007-12-18 | 2009-06-18 | Chong Chol Kim | Prosthetic Monolithic Spinal Discs and Method of Customizing and Constructing Discs |
US8241294B2 (en) | 2007-12-19 | 2012-08-14 | Depuy Spine, Inc. | Instruments for expandable corpectomy spinal fusion cage |
US8241363B2 (en) | 2007-12-19 | 2012-08-14 | Depuy Spine, Inc. | Expandable corpectomy spinal fusion cage |
WO2009094477A1 (en) * | 2008-01-25 | 2009-07-30 | Spinalmotion, Inc. | Compliant implantable prosthetic joint with preloaded spring |
US8167949B2 (en) | 2008-01-25 | 2012-05-01 | Aesculap Implant Systems, Llc | Hydrostatic interbody |
US8932355B2 (en) * | 2008-02-22 | 2015-01-13 | Coalign Innovations, Inc. | Spinal implant with expandable fixation |
US20100145455A1 (en) * | 2008-12-10 | 2010-06-10 | Innvotec Surgical, Inc. | Lockable spinal implant |
US8696751B2 (en) * | 2008-12-10 | 2014-04-15 | Coalign Innovations, Inc. | Adjustable distraction cage with linked locking mechanisms |
US8992620B2 (en) | 2008-12-10 | 2015-03-31 | Coalign Innovations, Inc. | Adjustable distraction cage with linked locking mechanisms |
US8377135B1 (en) | 2008-03-31 | 2013-02-19 | Nuvasive, Inc. | Textile-based surgical implant and related methods |
DE102008028589A1 (en) * | 2008-06-18 | 2009-12-24 | Rüger, Florian | Implant for insertion between vertebral bodies of the spine |
US7927375B2 (en) | 2008-09-12 | 2011-04-19 | Doty Keith L | Dynamic six-degrees-of-freedom intervertebral spinal disc prosthesis |
US8163022B2 (en) | 2008-10-14 | 2012-04-24 | Anulex Technologies, Inc. | Method and apparatus for the treatment of the intervertebral disc annulus |
US8182539B2 (en) * | 2008-10-23 | 2012-05-22 | Aesculap Implant Systems, Llc | Dynamic interbody with motion control mechanisms |
CN102341066B (en) * | 2008-12-31 | 2014-07-02 | 奥马尔·F·希门尼斯 | Methods and apparatus for vertebral body distraction and fusion employing flexure members |
JP2012514703A (en) | 2008-12-31 | 2012-06-28 | エフ. ヒメネス、オマール | Flexible joint configuration incorporating flexure members |
US8628577B1 (en) | 2009-03-19 | 2014-01-14 | Ex Technology, Llc | Stable device for intervertebral distraction and fusion |
US8123808B2 (en) * | 2009-04-16 | 2012-02-28 | Warsaw Orthopedic, Inc. | Vertebral endplate connection implant and method |
US8876905B2 (en) | 2009-04-29 | 2014-11-04 | DePuy Synthes Products, LLC | Minimally invasive corpectomy cage and instrument |
US8211178B2 (en) * | 2009-06-18 | 2012-07-03 | Warsaw Orthopedic | Intervertebral implant with a pivoting end cap |
US8226724B2 (en) | 2009-06-18 | 2012-07-24 | Doty Keith L | Intervertebral spinal disc prosthesis |
US8303663B2 (en) | 2009-07-22 | 2012-11-06 | Spinex Tec, Llc | Methods and apparatuses for vertebral body distraction and fusion employing a coaxial screw gear sleeve mechanism |
US8636746B2 (en) | 2009-12-31 | 2014-01-28 | Spinex Tec, Llc | Methods and apparatus for insertion of vertebral body distraction and fusion devices |
US8652153B2 (en) | 2010-01-11 | 2014-02-18 | Anulex Technologies, Inc. | Intervertebral disc annulus repair system and bone anchor delivery tool |
KR20120121396A (en) * | 2010-02-22 | 2012-11-05 | 신세스 게엠바하 | Total disc replacement with w-shaped spring elements |
US8647369B2 (en) * | 2010-05-19 | 2014-02-11 | Josef E. Gorek | Minimal profile anterior bracket for spinal fixation |
US8353964B2 (en) | 2010-11-04 | 2013-01-15 | Carpenter Clyde T | Anatomic total disc replacement |
US8377140B2 (en) | 2011-01-12 | 2013-02-19 | Ebi, Llc | Expandable spinal implant device |
US8740980B2 (en) | 2011-01-27 | 2014-06-03 | Warsaw Orthopedic, Inc. | Expandable medical implant |
US8388687B2 (en) | 2011-03-25 | 2013-03-05 | Flexuspine, Inc. | Interbody device insertion systems and methods |
US8277505B1 (en) | 2011-06-10 | 2012-10-02 | Doty Keith L | Devices for providing up to six-degrees of motion having kinematically-linked components and methods of use |
US10420654B2 (en) | 2011-08-09 | 2019-09-24 | Neuropro Technologies, Inc. | Bone fusion device, system and method |
US9358123B2 (en) | 2011-08-09 | 2016-06-07 | Neuropro Spinal Jaxx, Inc. | Bone fusion device, apparatus and method |
WO2013023096A1 (en) | 2011-08-09 | 2013-02-14 | Neuropro Technologies, Inc. | Bone fusion device, system and method |
US9526627B2 (en) | 2011-11-17 | 2016-12-27 | Exactech, Inc. | Expandable interbody device system and method |
US8287598B1 (en) | 2011-12-05 | 2012-10-16 | TrueMotion Spine, Inc. | True spinal motion preserving, shock absorbing, intervertebral spinal disc prosthesis |
US9532883B2 (en) | 2012-04-13 | 2017-01-03 | Neuropro Technologies, Inc. | Bone fusion device |
US10159583B2 (en) | 2012-04-13 | 2018-12-25 | Neuropro Technologies, Inc. | Bone fusion device |
US9433404B2 (en) | 2012-10-31 | 2016-09-06 | Suture Concepts Inc. | Method and apparatus for closing fissures in the annulus fibrosus |
US10786235B2 (en) | 2012-10-31 | 2020-09-29 | Anchor Innovation Medical, Inc. | Method and apparatus for closing a fissure in the annulus of an intervertebral disc, and/or for effecting other anatomical repairs and/or fixations |
US8945228B2 (en) | 2012-11-15 | 2015-02-03 | DePuy Synthes Products, LLC | Endplate for a vertebral implant |
CN103006356B (en) * | 2013-01-07 | 2018-03-16 | 刘小勇 | A kind of bionic type hydraulic movable artificial vertebral body |
WO2014117107A1 (en) | 2013-01-28 | 2014-07-31 | Cartiva, Inc. | Systems and methods for orthopedic repair |
US9737294B2 (en) | 2013-01-28 | 2017-08-22 | Cartiva, Inc. | Method and system for orthopedic repair |
US9492288B2 (en) | 2013-02-20 | 2016-11-15 | Flexuspine, Inc. | Expandable fusion device for positioning between adjacent vertebral bodies |
WO2014159225A2 (en) | 2013-03-14 | 2014-10-02 | Baxano Surgical, Inc. | Spinal implants and implantation system |
US9968460B2 (en) | 2013-03-15 | 2018-05-15 | Medsmart Innovation Inc. | Dynamic spinal segment replacement |
WO2014151934A1 (en) | 2013-03-15 | 2014-09-25 | Neuropro Technologies, Inc. | Bodiless bone fusion device, apparatus and method |
AU2014306454B2 (en) | 2013-08-16 | 2019-06-13 | Suture Concepts Inc. | Method and apparatus for closing a fissure in the annulus of an intervertebral disc, and/or for effecting other anatomical repairs and/or fixations |
US9615935B2 (en) * | 2014-01-30 | 2017-04-11 | Titan Spine, Llc | Thermally activated shape memory spring assemblies for implant expansion |
US8940049B1 (en) | 2014-04-01 | 2015-01-27 | Ex Technology, Llc | Expandable intervertebral cage |
US9486328B2 (en) | 2014-04-01 | 2016-11-08 | Ex Technology, Llc | Expandable intervertebral cage |
US9517144B2 (en) | 2014-04-24 | 2016-12-13 | Exactech, Inc. | Limited profile intervertebral implant with incorporated fastening mechanism |
US10398565B2 (en) | 2014-04-24 | 2019-09-03 | Choice Spine, Llc | Limited profile intervertebral implant with incorporated fastening and locking mechanism |
US10390959B2 (en) * | 2015-11-24 | 2019-08-27 | Agada Medical Ltd. | Intervertebral disc replacement |
US11298931B2 (en) | 2015-11-24 | 2022-04-12 | Agada Medical Ltd. | Intervertebral disc replacement |
AU2017202311B2 (en) | 2016-04-07 | 2022-03-03 | Howmedica Osteonics Corp. | Expandable interbody implant |
AU2017203369B2 (en) | 2016-05-20 | 2022-04-28 | Howmedica Osteonics Corp. | Expandable interbody implant with lordosis correction |
EP3292841B8 (en) | 2016-09-12 | 2023-05-31 | Howmedica Osteonics Corp. | Interbody implant with independent control of expansion at multiple locations |
US10314718B2 (en) | 2016-09-22 | 2019-06-11 | Loubert S. Suddaby | Expandable intervertebral fusion implant |
AU2017251734B2 (en) | 2016-10-26 | 2022-10-20 | Howmedica Osteonics Corp. | Expandable interbody implant with lateral articulation |
US10111760B2 (en) | 2017-01-18 | 2018-10-30 | Neuropro Technologies, Inc. | Bone fusion system, device and method including a measuring mechanism |
US10973657B2 (en) | 2017-01-18 | 2021-04-13 | Neuropro Technologies, Inc. | Bone fusion surgical system and method |
US10213321B2 (en) | 2017-01-18 | 2019-02-26 | Neuropro Technologies, Inc. | Bone fusion system, device and method including delivery apparatus |
US10729560B2 (en) | 2017-01-18 | 2020-08-04 | Neuropro Technologies, Inc. | Bone fusion system, device and method including an insertion instrument |
US11207192B2 (en) | 2017-01-26 | 2021-12-28 | Loubert S. Suddaby | Stand-alone expandable interbody spinal fusion device with integrated fixation mechanism |
US11701239B2 (en) | 2017-01-26 | 2023-07-18 | Loubert S. Suddaby | Stand-alone expandable interbody spinal fusion device with integrated fixation mechanism |
CN107485470B (en) * | 2017-09-12 | 2019-07-12 | 张坤 | A kind of cervical vertebra space dynamic stabilizing implanting apparatus for medical use in orthopedics department |
EP3456294A1 (en) | 2017-09-15 | 2019-03-20 | Stryker European Holdings I, LLC | Intervertebral body fusion device expanded with hardening material |
US10596010B2 (en) | 2017-09-18 | 2020-03-24 | Loubert S. Suddaby | Stand-alone expandable interbody spinal fusion device with locking mechanism |
US11219532B2 (en) | 2017-09-18 | 2022-01-11 | Loubert S. Suddaby | Stand-alone expandable interbody spinal fusion device with locking mechanism |
US10893951B2 (en) * | 2018-08-07 | 2021-01-19 | Minimally Invasive Spinal Technology, LLC | Device and method for correcting spinal deformities in patients |
US11234835B2 (en) | 2019-03-05 | 2022-02-01 | Octagon Spine Llc | Transversely expandable minimally invasive intervertebral cage |
US11497622B2 (en) | 2019-03-05 | 2022-11-15 | Ex Technology, Llc | Transversely expandable minimally invasive intervertebral cage and insertion and extraction device |
CN110141402B (en) * | 2019-05-17 | 2021-06-25 | 四川大学华西医院 | Intervertebral disc prosthesis |
Family Cites Families (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3426364A (en) * | 1966-08-25 | 1969-02-11 | Colorado State Univ Research F | Prosthetic appliance for replacing one or more natural vertebrae |
US4309777A (en) * | 1980-11-13 | 1982-01-12 | Patil Arun A | Artificial intervertebral disc |
US4553273A (en) * | 1983-11-23 | 1985-11-19 | Henry Ford Hospital | Vertebral body prosthesis and spine stabilizing method |
CA1283501C (en) * | 1987-02-12 | 1991-04-30 | Thomas P. Hedman | Artificial spinal disc |
DE8714635U1 (en) * | 1987-11-03 | 1987-12-17 | Waldemar Link Gmbh & Co, 2000 Hamburg, De | |
US4911718A (en) * | 1988-06-10 | 1990-03-27 | University Of Medicine & Dentistry Of N.J. | Functional and biocompatible intervertebral disc spacer |
CA2007210C (en) * | 1989-05-10 | 1996-07-09 | Stephen D. Kuslich | Intervertebral reamer |
US5062845A (en) * | 1989-05-10 | 1991-11-05 | Spine-Tech, Inc. | Method of making an intervertebral reamer |
US5458638A (en) * | 1989-07-06 | 1995-10-17 | Spine-Tech, Inc. | Non-threaded spinal implant |
US4932975A (en) * | 1989-10-16 | 1990-06-12 | Vanderbilt University | Vertebral prosthesis |
US5055104A (en) * | 1989-11-06 | 1991-10-08 | Surgical Dynamics, Inc. | Surgically implanting threaded fusion cages between adjacent low-back vertebrae by an anterior approach |
US5059193A (en) * | 1989-11-20 | 1991-10-22 | Spine-Tech, Inc. | Expandable spinal implant and surgical method |
DE9000094U1 (en) * | 1990-01-04 | 1991-01-31 | Mecron Medizinische Produkte Gmbh, 1000 Berlin, De | |
FR2659226B1 (en) * | 1990-03-07 | 1992-05-29 | Jbs Sa | PROSTHESIS FOR INTERVERTEBRAL DISCS AND ITS IMPLEMENTATION INSTRUMENTS. |
US5171278A (en) * | 1991-02-22 | 1992-12-15 | Madhavan Pisharodi | Middle expandable intervertebral disk implants |
US5390683A (en) * | 1991-02-22 | 1995-02-21 | Pisharodi; Madhavan | Spinal implantation methods utilizing a middle expandable implant |
US5123926A (en) * | 1991-02-22 | 1992-06-23 | Madhavan Pisharodi | Artificial spinal prosthesis |
EP0526682B1 (en) * | 1991-08-07 | 1997-03-05 | Oscobal Ag | Endoprosthesis with a metal wire mesh |
US5290312A (en) * | 1991-09-03 | 1994-03-01 | Alphatec | Artificial vertebral body |
DE4220218C2 (en) * | 1992-06-20 | 1994-09-22 | S & G Implants Gmbh | Implant with an open-cell or open-pore metal structure |
FR2692952B1 (en) * | 1992-06-25 | 1996-04-05 | Psi | IMPROVED SHOCK ABSORBER WITH MOVEMENT LIMIT. |
US5246458A (en) * | 1992-10-07 | 1993-09-21 | Graham Donald V | Artificial disk |
US5336223A (en) * | 1993-02-04 | 1994-08-09 | Rogers Charles L | Telescoping spinal fixator |
ES2141217T3 (en) * | 1993-02-10 | 2000-03-16 | Sulzer Spine Tech Inc | SURGICAL TOOL SET FOR STABILIZATION OF THE SPINE. |
US5405391A (en) * | 1993-02-16 | 1995-04-11 | Hednerson; Fraser C. | Fusion stabilization chamber |
FR2701650B1 (en) * | 1993-02-17 | 1995-05-24 | Psi | Double shock absorber for intervertebral stabilization. |
DE4417629B4 (en) * | 1993-06-24 | 2006-03-16 | SDGI Holdings, Inc., Wilmington | Implant for the replacement of vertebral bodies |
US5360430A (en) * | 1993-07-29 | 1994-11-01 | Lin Chih I | Intervertebral locking device |
US5458642A (en) * | 1994-01-18 | 1995-10-17 | Beer; John C. | Synthetic intervertebral disc |
US5571189A (en) * | 1994-05-20 | 1996-11-05 | Kuslich; Stephen D. | Expandable fabric implant for stabilizing the spinal motion segment |
DE9413778U1 (en) * | 1994-08-26 | 1996-01-04 | Schaefer Micomed Gmbh | Intervertebral implant |
US5591235A (en) * | 1995-03-15 | 1997-01-07 | Kuslich; Stephen D. | Spinal fixation device |
-
1996
- 1996-11-22 US US08/753,334 patent/US5827328A/en not_active Expired - Lifetime
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1997
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- 1997-11-06 EP EP03076508A patent/EP1342456B1/en not_active Expired - Lifetime
- 1997-11-06 DK DK97946354T patent/DK0948299T3/en active
- 1997-11-06 WO PCT/US1997/019610 patent/WO1998022050A1/en active IP Right Grant
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- 1997-11-06 CA CA002271800A patent/CA2271800C/en not_active Expired - Fee Related
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- 1997-11-06 JP JP52366698A patent/JP3677050B2/en not_active Expired - Fee Related
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- 1997-11-06 AT AT97946354T patent/ATE240702T1/en not_active IP Right Cessation
- 1997-11-06 AU AU51542/98A patent/AU719735B2/en not_active Ceased
- 1997-11-06 KR KR10-1999-7004529A patent/KR100394937B1/en not_active IP Right Cessation
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DE69733850T2 (en) | 2006-05-24 |
EP0948299B1 (en) | 2003-05-21 |
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JP2001504369A (en) | 2001-04-03 |
KR100394937B1 (en) | 2003-08-19 |
CA2271800A1 (en) | 1998-05-28 |
JP3677050B2 (en) | 2005-07-27 |
WO1998022050A1 (en) | 1998-05-28 |
ATE300257T1 (en) | 2005-08-15 |
EP0948299A1 (en) | 1999-10-13 |
DE69733850D1 (en) | 2005-09-01 |
DE69722244T2 (en) | 2003-12-11 |
DK0948299T3 (en) | 2003-06-23 |
EP1342456B1 (en) | 2005-07-27 |
US5827328A (en) | 1998-10-27 |
AU719735B2 (en) | 2000-05-18 |
DE69722244D1 (en) | 2003-06-26 |
KR20000069084A (en) | 2000-11-25 |
AU5154298A (en) | 1998-06-10 |
EP1342456A1 (en) | 2003-09-10 |
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