CA2252024A1 - Method and apparatus for the measurement of components of exhaled breath in humans - Google Patents

Method and apparatus for the measurement of components of exhaled breath in humans

Info

Publication number
CA2252024A1
CA2252024A1 CA002252024A CA2252024A CA2252024A1 CA 2252024 A1 CA2252024 A1 CA 2252024A1 CA 002252024 A CA002252024 A CA 002252024A CA 2252024 A CA2252024 A CA 2252024A CA 2252024 A1 CA2252024 A1 CA 2252024A1
Authority
CA
Canada
Prior art keywords
exhaled breath
components
subject
humans
measurement
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002252024A
Other languages
French (fr)
Other versions
CA2252024C (en
Inventor
Philip E. Silkoff
Patricia A. Mcclean
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Circassia AB
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27360752&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2252024(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US08/629,594 external-priority patent/US5795787A/en
Application filed by Individual filed Critical Individual
Publication of CA2252024A1 publication Critical patent/CA2252024A1/en
Application granted granted Critical
Publication of CA2252024C publication Critical patent/CA2252024C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
    • A61B5/097—Devices for facilitating collection of breath or for directing breath into or through measuring devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/497—Physical analysis of biological material of gaseous biological material, e.g. breath
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
    • A61B5/083—Measuring rate of metabolism by using breath test, e.g. measuring rate of oxygen consumption
    • A61B5/0836—Measuring rate of CO2 production

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medical Informatics (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

Methods and related equipment for measuring components of exhaled breath of a subject are provided which involve causing the subject to exhale into an appropriate apparatus for receiving exhaled breath;
increasing the pressure in the mouth of the subject to a level sufficient to close the vellum and isolate the nasopharynx during exhalation;
a means of monitoring nasal CO2 to confine vellum closure;
and measuring the level of one or more components of the collected exhaled breath. Endogenous nitric oxide is a preferred component of exhaled breath for monitoring and analysis.
CA002252024A 1996-04-09 1997-04-09 Method and apparatus for the measurement of components of exhaled breath in humans Expired - Lifetime CA2252024C (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US08/629,594 US5795787A (en) 1996-04-09 1996-04-09 Method and apparatus for the measurement of exhaled nitric oxide in humans
US1725196P 1996-05-10 1996-05-10
US08/827,703 1997-04-09
US08/629,594 1997-04-09
PCT/IB1997/000525 WO1997038307A1 (en) 1996-04-09 1997-04-09 Method and apparatus for the measurement of components of exhaled breath in humans
US08/827,703 US6010459A (en) 1996-04-09 1997-04-09 Method and apparatus for the measurement of components of exhaled breath in humans
US60/017,251 1997-04-09

Publications (2)

Publication Number Publication Date
CA2252024A1 true CA2252024A1 (en) 1997-10-16
CA2252024C CA2252024C (en) 2006-09-19

Family

ID=27360752

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002252024A Expired - Lifetime CA2252024C (en) 1996-04-09 1997-04-09 Method and apparatus for the measurement of components of exhaled breath in humans

Country Status (8)

Country Link
US (1) US6010459A (en)
EP (1) EP0892926B2 (en)
JP (1) JP2000506601A (en)
AT (1) ATE219836T1 (en)
AU (1) AU719940B2 (en)
CA (1) CA2252024C (en)
DE (2) DE892926T1 (en)
WO (1) WO1997038307A1 (en)

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US6010459A (en) 2000-01-04
EP0892926A1 (en) 1999-01-27
AU2400797A (en) 1997-10-29
AU719940B2 (en) 2000-05-18
DE69713581D1 (en) 2002-08-01
WO1997038307A1 (en) 1997-10-16
EP0892926B2 (en) 2006-12-06
DE69713581T3 (en) 2007-09-13
CA2252024C (en) 2006-09-19
EP0892926B1 (en) 2002-06-26
DE892926T1 (en) 1999-12-09
JP2000506601A (en) 2000-05-30
ATE219836T1 (en) 2002-07-15
DE69713581T2 (en) 2003-02-27

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