CA2249235A1 - Apparatus and method for handling fluid samples of body materials - Google Patents

Apparatus and method for handling fluid samples of body materials

Info

Publication number
CA2249235A1
CA2249235A1 CA002249235A CA2249235A CA2249235A1 CA 2249235 A1 CA2249235 A1 CA 2249235A1 CA 002249235 A CA002249235 A CA 002249235A CA 2249235 A CA2249235 A CA 2249235A CA 2249235 A1 CA2249235 A1 CA 2249235A1
Authority
CA
Canada
Prior art keywords
viewing
staining solution
handling
chambers
fluid samples
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002249235A
Other languages
French (fr)
Other versions
CA2249235C (en
Inventor
Walter Greenfield
Mark J. Chiapetta
Todd M. Dematteo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Diasys Corp
Original Assignee
Diasys Corporation
Walter Greenfield
Mark J. Chiapetta
Todd M. Dematteo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Diasys Corporation, Walter Greenfield, Mark J. Chiapetta, Todd M. Dematteo filed Critical Diasys Corporation
Publication of CA2249235A1 publication Critical patent/CA2249235A1/en
Application granted granted Critical
Publication of CA2249235C publication Critical patent/CA2249235C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/34—Microscope slides, e.g. mounting specimens on microscope slides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31—Apparatus therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/493—Physical analysis of biological material of liquid biological material urine
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1095—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31—Apparatus therefor
    • G01N1/312—Apparatus therefor for samples mounted on planar substrates
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/11—Automated chemical analysis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/11—Automated chemical analysis
    • Y10T436/112499—Automated chemical analysis with sample on test slide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/11—Automated chemical analysis
    • Y10T436/117497—Automated chemical analysis with a continuously flowing sample or carrier stream

Abstract

A system for handling a body specimen is described for particular use in the handling of fecal specimens which are to be treated with a stain for enhancing its visibility. The system, as shown in the Figure, includes dual optical viewing chambers (30, 32) mounted alongside of each other on a frame with appropriate tubing connecting ports (36.1, 36.2) of the viewing chambers to liquid specimen container (22) and a staining solution container (68). The staining solution container is connected to one of the tubings (60) leading to a viewing chamber (32) so that the drawing action from a pump (50) connected to ports (36.3, 36.4) on the other side of the viewing chambers can force an automatic mixing of the staining solution with one of the liquid specimen being drawn into one of the viewing chambers. Controls and techniques for operating the system are described.
CA002249235A 1996-03-25 1997-03-06 Apparatus and method for handling fluid samples of body materials Expired - Fee Related CA2249235C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1409696P 1996-03-25 1996-03-25
US60/014,096 1996-03-25
PCT/US1997/004354 WO1997036166A1 (en) 1996-03-25 1997-03-06 Apparatus and method for handling fluid samples of body materials

Publications (2)

Publication Number Publication Date
CA2249235A1 true CA2249235A1 (en) 1997-10-02
CA2249235C CA2249235C (en) 2002-05-07

Family

ID=21763507

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002249235A Expired - Fee Related CA2249235C (en) 1996-03-25 1997-03-06 Apparatus and method for handling fluid samples of body materials

Country Status (7)

Country Link
US (1) US5895762A (en)
EP (1) EP0890106A4 (en)
JP (1) JP3316574B2 (en)
AU (1) AU719091B2 (en)
BR (1) BR9708250A (en)
CA (1) CA2249235C (en)
WO (1) WO1997036166A1 (en)

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US8852862B2 (en) 2004-05-03 2014-10-07 Handylab, Inc. Method for processing polynucleotide-containing samples
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WO2005111580A1 (en) * 2004-05-07 2005-11-24 Optiscan Biomedical Corporation Sample element with fringing-reduction capabilities
US20060030790A1 (en) * 2004-08-06 2006-02-09 Braig James R Sample element with barrier material and vacuum
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US8594768B2 (en) 2004-11-01 2013-11-26 Michael J. Phillips Surgical system with clips for identifying the orientation of a tissue sample
EP1762877B1 (en) * 2005-09-13 2010-11-17 Albert-Ludwigs-Universität Freiburg Microscopy method employing a spatially modulated illumination
US7998708B2 (en) 2006-03-24 2011-08-16 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
US11806718B2 (en) 2006-03-24 2023-11-07 Handylab, Inc. Fluorescence detector for microfluidic diagnostic system
JP5415253B2 (en) 2006-03-24 2014-02-12 ハンディラブ・インコーポレーテッド Integrated system for processing microfluidic samples and methods of use thereof
US10900066B2 (en) 2006-03-24 2021-01-26 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
US8088616B2 (en) 2006-03-24 2012-01-03 Handylab, Inc. Heater unit for microfluidic diagnostic system
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WO2008060604A2 (en) 2006-11-14 2008-05-22 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
WO2008061165A2 (en) 2006-11-14 2008-05-22 Handylab, Inc. Microfluidic cartridge and method of making same
US8105783B2 (en) 2007-07-13 2012-01-31 Handylab, Inc. Microfluidic cartridge
US8182763B2 (en) 2007-07-13 2012-05-22 Handylab, Inc. Rack for sample tubes and reagent holders
US8287820B2 (en) 2007-07-13 2012-10-16 Handylab, Inc. Automated pipetting apparatus having a combined liquid pump and pipette head system
US20090136385A1 (en) 2007-07-13 2009-05-28 Handylab, Inc. Reagent Tube
US9618139B2 (en) 2007-07-13 2017-04-11 Handylab, Inc. Integrated heater and magnetic separator
CA2693654C (en) 2007-07-13 2018-02-13 Handylab, Inc. Polynucleotide capture materials, and methods of using same
USD621060S1 (en) 2008-07-14 2010-08-03 Handylab, Inc. Microfluidic cartridge
US8133671B2 (en) 2007-07-13 2012-03-13 Handylab, Inc. Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples
US9186677B2 (en) 2007-07-13 2015-11-17 Handylab, Inc. Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples
US8381169B2 (en) * 2007-10-30 2013-02-19 International Business Machines Corporation Extending unified process and method content to include dynamic and collaborative content
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Also Published As

Publication number Publication date
WO1997036166A1 (en) 1997-10-02
AU2534097A (en) 1997-10-17
JP3316574B2 (en) 2002-08-19
AU719091B2 (en) 2000-05-04
CA2249235C (en) 2002-05-07
EP0890106A1 (en) 1999-01-13
JP2002504986A (en) 2002-02-12
EP0890106A4 (en) 2002-08-28
US5895762A (en) 1999-04-20
BR9708250A (en) 2000-01-04

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