CA2248862A1 - Calculation of radiation therapy dose using all particle monte carlo transport - Google Patents

Calculation of radiation therapy dose using all particle monte carlo transport

Info

Publication number
CA2248862A1
CA2248862A1 CA002248862A CA2248862A CA2248862A1 CA 2248862 A1 CA2248862 A1 CA 2248862A1 CA 002248862 A CA002248862 A CA 002248862A CA 2248862 A CA2248862 A CA 2248862A CA 2248862 A1 CA2248862 A1 CA 2248862A1
Authority
CA
Canada
Prior art keywords
monte carlo
biological
dose distributions
calculation
dose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002248862A
Other languages
French (fr)
Other versions
CA2248862C (en
Inventor
William P. Chandler
Christine L. Hartmann Siantar
James A. Rathkopf
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California
Original Assignee
The Regents Of The University Of California
William P. Chandler
Christine L. Hartmann Siantar
James A. Rathkopf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Regents Of The University Of California, William P. Chandler, Christine L. Hartmann Siantar, James A. Rathkopf filed Critical The Regents Of The University Of California
Publication of CA2248862A1 publication Critical patent/CA2248862A1/en
Application granted granted Critical
Publication of CA2248862C publication Critical patent/CA2248862C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/103—Treatment planning systems
    • A61N5/1031—Treatment planning systems using a specific method of dose optimization
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/103—Treatment planning systems
    • A61N5/1031—Treatment planning systems using a specific method of dose optimization
    • A61N2005/1034—Monte Carlo type methods; particle tracking
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1042—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy with spatial modulation of the radiation beam within the treatment head
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S378/00—X-ray or gamma ray systems or devices
    • Y10S378/901—Computer tomography program or processor

Abstract

The actual radiation dose absorbed in the body is calculated using three-dimensional Monte Carlo transport (19). Neutrons, protons, deuterons, tritons, helium-3, alpha particles, photons, electrons, and positrons are transported in a completely coupled manner, using this Monte Carlo All-Particle Method (MCAPM) (18). The major elements of the invention include: computer hardware , user description of the patient, description of the radiation source, physical databases, Monte Carlo transport, and output of dose distributions (15). This facilitated the estimation of dose distributions on a Cartesian grid for neutrons, photons, electrons, positrons, and heavy charged-particles incident on any biological target, with resolutions ranging from microns to centimeters. Calculations can be extended to estimate dose distributions on general-geometry (non-Cartesian) grids for biological and/or non-biological media.
CA002248862A 1996-03-05 1997-02-28 Calculation of radiation therapy dose using all particle monte carlo transport Expired - Fee Related CA2248862C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/610,917 1996-03-05
US08/610,917 US5870697A (en) 1996-03-05 1996-03-05 Calculation of radiation therapy dose using all particle Monte Carlo transport
PCT/US1997/003328 WO1997032630A1 (en) 1996-03-05 1997-02-28 Calculation of radiation therapy dose using all particle monte carlo transport

Publications (2)

Publication Number Publication Date
CA2248862A1 true CA2248862A1 (en) 1997-09-12
CA2248862C CA2248862C (en) 2005-01-04

Family

ID=24446922

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002248862A Expired - Fee Related CA2248862C (en) 1996-03-05 1997-02-28 Calculation of radiation therapy dose using all particle monte carlo transport

Country Status (6)

Country Link
US (1) US5870697A (en)
EP (1) EP0956099A4 (en)
JP (1) JP2000507848A (en)
AU (1) AU2317897A (en)
CA (1) CA2248862C (en)
WO (1) WO1997032630A1 (en)

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Also Published As

Publication number Publication date
EP0956099A4 (en) 2000-04-26
WO1997032630A1 (en) 1997-09-12
EP0956099A1 (en) 1999-11-17
US5870697A (en) 1999-02-09
CA2248862C (en) 2005-01-04
JP2000507848A (en) 2000-06-27
AU2317897A (en) 1997-09-22

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